1XM2A

Crystal structure of human prl-1
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
APVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine Phosphatase
total genus 41
structure length 149
sequence length 149
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2004-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1xm2A00
4OHLA 3F99A 3V0JA 4GFUA 2RF6A 4Y14A 3PS5A 2CNFA 3QCGA 2PSZA 3S3EA 1U25A 2QDPA 3RGQA 4YR8B 1V3AA 2QCJA 3I36A 5J8RA 1YZ4A 1C86A 4KI9A 4Z6BA 4WTYA 1C88A 4JMKA 1PTUA 2PQ5A 3BM8A 2I6JA 2CMCA 1PTYA 4ERCA 5K24A 1XM2A 4GRZA 5K9VA 3EU0A 2H04A 2E0TA 2FH7A 4H34A 2VEYA 1KAVA 1NNYA 2QBRA 3NMEA 1OESA 5KADA 3S4EA 4ZI4A 2I4EA 1JF7A 5I6VA 1LQFA 1YN9A 2CJZA 3EZZA 3D9CA 4MBBA 2BZLA 2HY3A 3V0IA 2F6WA 1EEOA 1OHDA 5KA1A 1PXHA 2I6IA 3QKPA 2C7SA 4QBWA 3I80A 2HNPA 5AWXA 5BX1A 2NZ6A 3S3FA 2PI7A 2B4PA 3QCEA 4QUMA 1RXDA 2VEVA 2BV5A 3SR9A 2Y2FA 3V0EA 5K22A 3F41A 2F6VA 5KA3A 3RZ2A 3O4UA 3QCHA 4OHIA 5KA2A 1L8KA 4HJQA 2FJNA 3U96A 3QCJA 3QCIA 2I75A 1I9SA 1NL9A 4H1OA 3GXHA 2A3KA 4NX8A 3ZM3A 2C46A 2J17A 1OEOX 5HDEA 5KA4A 3CWEA 2NT7A 5KACA 3QCCA 3MOWA 4J51A 1Q6PA 4WU2A 1YPTA 1ZCKA 1Q6SA 1X24A 3EMUA 2CFVA 1G7FA 1OEVA 4B04A 5BZZA 1G4WR 3D1QA 1LARA 5KA9A 2I6MA 3V0FA 3ZM2A 1OETA 1C85A 1L8GA 1A5YA 1U24A 3OLRA 2GP0A 1G1FA 3QCFA 3RGOA 2HCMA 2HB1A 3A5JA 1J4XA 4ZN5A 1C87A 4RH5A 5MMZB 2CNHA 1Q6JA 1PH0A 2YDUA 3S3HA 2H03A 3MOZA 2AZRA 1ZCLA 1FPRA 1PA9A 2I6OA 1GWZA 2I5XA 4RHGA 1C83A 3QCMA 1Q6MA 4RI4A 2P6XA 2QBSA 2CMAA 2CM7A 4D3PA 1Q6TA 2OUDA 5IBMA 3D44A 2R0BA 2OOQA 3F9AA 2F6FA 1C84A 1JLNA 3A5KA 5KAAA 1ECVA 5K9WA 2VEUA 1GFYA 1T4JA 3OMHA 1U26A 1G1GA 1ZZWA 3CM3A 2WGPA 4PYHA 2Q47A 2I4GA 2PT0A 2B49A 3BRHA 5EHPA 2F46A 4R30A 1EENA 2A8BA 3D1HA 3EB1A 2M3VA 4GWFA 2AHSA 2I42A 1I57A 2B3OA 2CMBA 2F70A 4D3RA 2Q05A 3N0AA 4GS0A 1WCHA 5BZXA 2PBNA 4NNDA 2HVLA 2J16B 1YFOA 4WU3A 1PYNA 1NZ7A 2BIJA 1OEUA 5KABA 4GE5A 3F9BA 5M43A 3ZM0A 4OHHA 4S0GA 2GJTA 2G59A 3O5XA 1PTVA 2I1YA 1PTTA 4RH9A 2QEPA 2F71A 1YTSA 4PVGA 2MBCA 2CNIA 2H02A 2NLKA 4JMJA 2ESBA 3BLUA 2NT2A 2F6TA 3ZMQA 1SUGA 1MKPA 4QAPA 1YTWA 2CNEA 2F6YA 1FPZA 4ICZA 1AAXA 1XXPA 1G7GA 2PA5A 2HC1A 4GRYA 3ZM1A 1RPMA 2FJMA 4GE6A 5K25A 4ZRTA 3QCLA 4RI5A 2ZMMA 4GFVA 2H4VA 1KAKA 1OEMX 1XBOA 2HXPA 2H4KA 3S3KA 1P15A 1YGRA 3QCNA 1ZC0A 4YAAA 1QXKA 2JJDA 2P4DA 1XRIA 2DXPA 2I6PA 3F81A 1NWEA 2NV5A 4DGXA 4WOHA 2OZ5A 4KYRA 1I9TA 2B4SA 4Y2EA 2QDCA 4DGPA 2B4UA 2Y96A 4NWFA 1LYVA 1YGUA 5BUGA 4QUNA 2QBPA 5KA0A 2CM2A 1VHRA 4NWGA 4R0SA 5LXQB 1OHEA 3O4TA 1M3GA 1QZ0A 1Q1MA 1T49A 3O4SA 5KA7A 5K23A 2HNQA 4OHEA 4R0TA 2I3RA 5EHRA 3O3LA 3V0HA 4D3QA 3QCKA 3RO1A 2CM3A 1ONYA 3AWEA 1WAXA 2BGDA 1G1HA 4OHDA 3MMJA 3QCDA 1WRMA 2B07A 1XXVA 3V0DA 3I7ZA 1PA1A 2QDMA 2HC2A 2VEWA 3ZV2A 1Q6NA 3LJ8A 4HRFA 1BZJA 4JNBA 1BZCA 3AWGA 3D42A 2CNGA 5KA8A 4BJOA 2GWOA 5IBSA 4IKCA 2H4GA 2J16A 2ZN7A 2CM8A 3M4UA 2I3UA 2VEXA 3H2XA 3GXGA 2B4OA 2F6ZA 1T48A 4KYQA 1ONZA 1YWFA 3QCBA 4NYHA 4TVVA 1YTNA 3V0GA 5GTJA 2IMGA 4RKKA 4QAHA 3SMEA 1FQ1A 2NTAA 4BPCA 3BLTA 3AWFA 4JBCA 3QKQA 3EAXA 1R6HA 4HJPA 4AZ1A 2G6ZA 2BGEA 1D5RA 3S4OA 2QCTA 3B7OA 2QBQA 1G4US 3D1OA 4GE2A 3ZMPA 2I4HA 1NWLA 4I8NA 1BZHA 4QBEA 1NO6A 2SHPA 4RDDA 1OHCA 2OC3A
chains in the Genus database with same CATH superfamily
4OHLA 3F99A 1P3DA 4GFUA 3V0JA 2RF6A 4Y14A 3PS5A 2CNFA 3QCGA 4UAGA 2PSZA 3S3EA 1U25A 2QDPA 3RGQA 4YR8B 1V3AA 2QCJA 3I36A 5J8RA 1YZ4A 1C86A 4KI9A 4Z6BA 4WTYA 1C88A 4JMKA 1PTUA 2PQ5A 3BM8A 2F00A 2I6JA 2CMCA 1PTYA 4ERCA 5K24A 1XM2A 4GRZA 2AM2A 5K9VA 3EU0A 3ZM6A 2H04A 2E0TA 2FH7A 4H34A 2VEYA 1KAVA 1NNYA 2QBRA 1W7KA 3NMEA 1OESA 2VOSA 5KADA 3S4EA 2AM1A 2UAGA 4ZI4A 2I4EA 1JF7A 5I6VA 1E0DA 1LQFA 1YN9A 2CJZA 3EZZA 3D9CA 4MBBA 2BZLA 2HY3A 3V0IA 2F6WA 1EEOA 1OHDA 5KA1A 1PXHA 2I6IA 3QKPA 1UAGA 2C7SA 4QBWA 3I80A 2HNPA 5AWXA 5BX1A 2NZ6A 3S3FA 2PI7A 2B4PA 2JFGA 3QCEA 4C12A 4QUMA 1RXDA 2VEVA 2Y1OA 2BV5A 3SR9A 2Y2FA 3V0EA 1O5ZA 5K22A 3F41A 2F6VA 3LK7A 5KA3A 3RZ2A 3O4UA 2WJPA 3QCHA 4OHIA 2GC6A 2VORA 5KA2A 1L8KA 4HJQA 2FJNA 3U96A 3QCJA 3QCIA 2I75A 1I9SA 1NL9A 4H1OA 3GXHA 2A3KA 2GCAA 2Y66A 4NX8A 3ZM3A 2C46A 2J17A 1OEOX 5HDEA 5KA4A 3CWEA 2NT7A 5KACA 3QCCA 3MOWA 4J51A 1Q6PA 4WU2A 1YPTA 1ZCKA 1Q6SA 1X24A 3EMUA 2CFVA 1G7FA 1OEVA 4B04A 5BZZA 1G4WR 3D1QA 1LARA 5KA9A 2I6MA 2VTDA 3V0FA 3ZM2A 1OETA 3MVNA 1C85A 1L8GA 1A5YA 1U24A 3OLRA 2GP0A 4BUCA 1G1FA 3QCFA 3RGOA 2X5OA 2HCMA 2HB1A 3A5JA 1J4XA 2GC5A 4ZN5A 1C87A 4RH5A 5MMZB 2CNHA 1Q6JA 1PH0A 2YDUA 3S3HA 2H03A 3MOZA 2AZRA 1ZCLA 1FPRA 1PA9A 2I6OA 1GWZA 1EEHA 2I5XA 4RHGA 1C83A 3NRSA 1Q6MA 3QCMA 4RI4A 2P6XA 2QBSA 2CMAA 5A5FA 2CM7A 2VTEA 3N2AA 4D3PA 1GQYA 1Q6TA 2OUDA 5IBMA 3D44A 2R0BA 2OOQA 3F9AA 2F6FA 1C84A 1JLNA 3A5KA 5KAAA 1ECVA 5K9WA 2VEUA 1GFYA 1T4JA 3OMHA 1U26A 1G1GA 1ZZWA 3CM3A 3HN7A 2WGPA 4PYHA 2Q47A 4CVKA 2I4GA 2PT0A 2B49A 3BRHA 5EHPA 2F46A 4R30A 1EENA 1P31A 2A8BA 3D1HA 3EB1A 3UAGA 2M3VA 4GWFA 2AHSA 2I42A 2GCBA 1I57A 2B3OA 2CMBA 2F70A 4D3RA 2Q05A 3N0AA 4GS0A 1WCHA 5BZXA 5A5EA 2PBNA 4NNDA 2HVLA 2J16B 1YFOA 4WU3A 1PYNA 1NZ7A 2BIJA 1OEUA 5KABA 4GE5A 3F9BA 5M43A 3ZM0A 4OHHA 4S0GA 2GJTA 2G59A 3O5XA 2UUOA 1PTVA 2I1YA 1PTTA 4RH9A 2QEPA 2F71A 4QDIA 1YTSA 4PVGA 2XJAA 2MBCA 2CNIA 4BUBA 2H02A 2NLKA 4JMJA 2ESBA 3BLUA 2NT2A 2F6TA 3ZMQA 1SUGA 3QCZA 1MKPA 2Y68A 4QAPA 1YTWA 2CNEA 2F6YA 1FPZA 4ICZA 1AAXA 1XXPA 1JBWA 1G7GA 2PA5A 3ZM5A 2HC1A 4GRYA 3ZM1A 1RPMA 2FJMA 4GE6A 5K25A 4ZRTA 3QCLA 4RI5A 2ZMMA 4GFVA 2H4VA 1KAKA 1OEMX 1XBOA 2HXPA 4CVMA 2H4KA 3S3KA 1P15A 1YGRA 3QCNA 3ZL8A 1E8CA 1ZC0A 4CVLA 1GG4A 4YAAA 1FGSA 1QXKA 2JJDA 1GQQA 2WTZA 2P4DA 1XRIA 2DXPA 2I6PA 3F81A 1NWEA 2NV5A 4DGXA 4WOHA 2OZ5A 4KYRA 2JFHA 1I9TA 2B4SA 4Y2EA 2QDCA 4DGPA 2B4UA 2Y96A 4NWFA 1LYVA 1YGUA 5BUGA 4QUNA 2QBPA 5KA0A 2CM2A 1VHRA 4NWGA 4R0SA 5LXQB 1OHEA 3O4TA 1M3GA 2JFFA 1QZ0A 4ZIYA 3PYZA 1Q1MA 1T49A 3O4SA 5KA7A 5K23A 2HNQA 4OHEA 4R0TA 2I3RA 1J6UA 5EHRA 3O3LA 3V0HA 4D3QA 2Y67A 3QCKA 3RO1A 2CM3A 1ONYA 3AWEA 1WAXA 2BGDA 1G1HA 4OHDA 3MMJA 3QCDA 4HV4A 1WRMA 2B07A 1XXVA 3V0DA 2XPCA 3I7ZA 4C13A 1PA1A 2QDMA 1W78A 2HC2A 2VEWA 3ZV2A 1Q6NA 3LJ8A 4HRFA 1BZJA 4JNBA 1BZCA 3AWGA 3D42A 2CNGA 5KA8A 4BJOA 2GWOA 5IBSA 4IKCA 2H4GA 2J16A 2ZN7A 2CM8A 3M4UA 2I3UA 2VEXA 3H2XA 3GXGA 2B4OA 2F6ZA 1T48A 2UUPA 4KYQA 1ONZA 1JBVA 1YWFA 3QCBA 4NYHA 4TVVA 1YTNA 3V0GA 5GTJA 2IMGA 4RKKA 4QAHA 3SMEA 1FQ1A 2NTAA 4BPCA 4QF5A 3BLTA 3AWFA 4JBCA 3QKQA 3EAXA 1R6HA 4HJPA 4AZ1A 2G6ZA 2BGEA 1D5RA 3S4OA 2QCTA 3B7OA 2QBQA 1G4US 3D1OA 4GE2A 3ZMPA 2I4HA 1NWLA 4I8NA 1BZHA 4QBEA 1NO6A 2SHPA 4RDDA 1OHCA 2OC3A
chains in the Genus database with same CATH topology
4OHLA 3F99A 3V0JA 4GFUA 2RF6A 4Y14A 3PS5A 2CNFA 3QCGA 2PSZA 3S3EA 1U25A 2QDPA 3RGQA 4YR8B 1V3AA 2QCJA 3I36A 5J8RA 1YZ4A 1C86A 4KI9A 4Z6BA 4WTYA 1C88A 4JMKA 1PTUA 2PQ5A 3BM8A 2I6JA 2CMCA 1PTYA 4ERCA 5K24A 1XM2A 4GRZA 5K9VA 3EU0A 2H04A 2E0TA 2FH7A 4H34A 2VEYA 1KAVA 1NNYA 2QBRA 3NMEA 1OESA 5KADA 3S4EA 4ZI4A 2I4EA 1JF7A 5I6VA 1LQFA 1YN9A 2CJZA 3EZZA 3D9CA 4MBBA 2BZLA 2HY3A 3V0IA 2F6WA 1EEOA 1OHDA 5KA1A 1PXHA 2I6IA 3QKPA 2C7SA 4QBWA 3I80A 2HNPA 5AWXA 5BX1A 2NZ6A 3S3FA 2PI7A 2B4PA 3QCEA 4QUMA 1RXDA 2VEVA 2BV5A 3SR9A 2Y2FA 3V0EA 5K22A 3F41A 2F6VA 5KA3A 3RZ2A 3O4UA 3QCHA 4OHIA 5KA2A 1L8KA 4HJQA 2FJNA 3U96A 3QCJA 3QCIA 2I75A 1I9SA 1NL9A 4H1OA 3GXHA 2A3KA 4NX8A 3ZM3A 2C46A 2J17A 1OEOX 5HDEA 5KA4A 3CWEA 2NT7A 5KACA 3QCCA 3MOWA 4J51A 1Q6PA 4WU2A 1YPTA 1ZCKA 1Q6SA 1X24A 3EMUA 2CFVA 1G7FA 1OEVA 4B04A 5BZZA 1G4WR 3D1QA 1LARA 5KA9A 2I6MA 3V0FA 3ZM2A 1OETA 1C85A 1L8GA 1A5YA 1U24A 3OLRA 2GP0A 1G1FA 3QCFA 3RGOA 2HCMA 2HB1A 3A5JA 1J4XA 4ZN5A 1C87A 4RH5A 5MMZB 2CNHA 1Q6JA 1PH0A 2YDUA 3S3HA 2H03A 3MOZA 2AZRA 1ZCLA 1FPRA 1PA9A 2I6OA 1GWZA 2I5XA 4RHGA 1C83A 3QCMA 1Q6MA 4RI4A 2P6XA 2QBSA 2CMAA 2CM7A 4D3PA 1Q6TA 2OUDA 5IBMA 3D44A 2R0BA 2OOQA 3F9AA 2F6FA 1C84A 1JLNA 3A5KA 5KAAA 1ECVA 5K9WA 2VEUA 1GFYA 1T4JA 3OMHA 1U26A 1G1GA 1ZZWA 3CM3A 2WGPA 4PYHA 2Q47A 2I4GA 2PT0A 2B49A 3BRHA 5EHPA 2F46A 4R30A 1EENA 2A8BA 3D1HA 3EB1A 2M3VA 4GWFA 2AHSA 2I42A 1I57A 2B3OA 2CMBA 2F70A 4D3RA 2Q05A 3N0AA 4GS0A 1WCHA 5BZXA 2PBNA 4NNDA 2HVLA 2J16B 1YFOA 4WU3A 1PYNA 1NZ7A 2BIJA 1OEUA 5KABA 4GE5A 3F9BA 5M43A 3ZM0A 4OHHA 4S0GA 2GJTA 2G59A 3O5XA 1PTVA 2I1YA 1PTTA 4RH9A 2QEPA 2F71A 1YTSA 4PVGA 2MBCA 2CNIA 2H02A 2NLKA 4JMJA 2ESBA 3BLUA 2NT2A 2F6TA 3ZMQA 1SUGA 1MKPA 4QAPA 1YTWA 2CNEA 2F6YA 1FPZA 4ICZA 1AAXA 1XXPA 1G7GA 2PA5A 2HC1A 4GRYA 3ZM1A 1RPMA 2FJMA 4GE6A 5K25A 4ZRTA 3QCLA 4RI5A 2ZMMA 4GFVA 2H4VA 1KAKA 1OEMX 1XBOA 2HXPA 2H4KA 3S3KA 1P15A 1YGRA 3QCNA 1ZC0A 4YAAA 1QXKA 2JJDA 2P4DA 1XRIA 2DXPA 2I6PA 3F81A 1NWEA 2NV5A 4DGXA 4WOHA 2OZ5A 4KYRA 1I9TA 2B4SA 4Y2EA 2QDCA 4DGPA 2B4UA 2Y96A 4NWFA 1LYVA 1YGUA 5BUGA 4QUNA 2QBPA 5KA0A 2CM2A 1VHRA 4NWGA 4R0SA 5LXQB 1OHEA 3O4TA 1M3GA 1QZ0A 1Q1MA 1T49A 3O4SA 5KA7A 5K23A 2HNQA 4OHEA 4R0TA 2I3RA 5EHRA 3O3LA 3V0HA 4D3QA 3QCKA 3RO1A 2CM3A 1ONYA 3AWEA 1WAXA 2BGDA 1G1HA 4OHDA 3MMJA 3QCDA 1WRMA 2B07A 1XXVA 3V0DA 3I7ZA 1PA1A 2QDMA 2HC2A 2VEWA 3ZV2A 1Q6NA 3LJ8A 4HRFA 1BZJA 4JNBA 1BZCA 3AWGA 3D42A 2CNGA 5KA8A 4BJOA 2GWOA 5IBSA 4IKCA 2H4GA 2J16A 2ZN7A 2CM8A 3M4UA 2I3UA 2VEXA 3H2XA 3GXGA 2B4OA 2F6ZA 1T48A 4KYQA 1ONZA 1YWFA 3QCBA 4NYHA 4TVVA 1YTNA 3V0GA 5GTJA 2IMGA 4RKKA 4QAHA 3SMEA 1FQ1A 2NTAA 4BPCA 3BLTA 3AWFA 4JBCA 3QKQA 3EAXA 1R6HA 4HJPA 4AZ1A 2G6ZA 2BGEA 1D5RA 3S4OA 2QCTA 3B7OA 2QBQA 1G4US 3D1OA 4GE2A 3ZMPA 2I4HA 1NWLA 4I8NA 1BZHA 4QBEA 1NO6A 2SHPA 4RDDA 1OHCA 2OC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OHL A;  3F99 A;  3V0J A;  4GFU A;  2RF6 A;  4Y14 A;  3PS5 A;  2CNF A;  3QCG A;  2PSZ A;  3S3E A;  1U25 A;  2QDP A;  3RGQ A;  4YR8 B;  1V3A A;  2QCJ A;  3I36 A;  5J8R A;  1YZ4 A;  1C86 A;  4KI9 A;  4Z6B A;  4WTY A;  1C88 A;  4JMK A;  1PTU A;  2PQ5 A;  3BM8 A;  2I6J A;  2CMC A;  1PTY A;  4ERC A;  5K24 A;  1XM2 A;  4GRZ A;  5K9V A;  3EU0 A;  2H04 A;  2E0T A;  2FH7 A;  4H34 A;  2VEY A;  1KAV A;  1NNY A;  2QBR A;  3NME A;  1OES A;  5KAD A;  3S4E A;  4ZI4 A;  2I4E A;  1JF7 A;  5I6V A;  1LQF A;  1YN9 A;  2CJZ A;  3EZZ A;  3D9C A;  4MBB A;  2BZL A;  2HY3 A;  3V0I A;  2F6W A;  1EEO A;  1OHD A;  5KA1 A;  1PXH A;  2I6I A;  3QKP A;  2C7S A;  4QBW A;  3I80 A;  2HNP A;  5AWX A;  5BX1 A;  2NZ6 A;  3S3F A;  2PI7 A;  2B4P A;  3QCE A;  4QUM A;  1RXD A;  2VEV A;  2BV5 A;  3SR9 A;  2Y2F A;  3V0E A;  5K22 A;  3F41 A;  2F6V A;  5KA3 A;  3RZ2 A;  3O4U A;  3QCH A;  4OHI A;  5KA2 A;  1L8K A;  4HJQ A;  2FJN A;  3U96 A;  3QCJ A;  3QCI A;  2I75 A;  1I9S A;  1NL9 A;  4H1O A;  3GXH A;  2A3K A;  4NX8 A;  3ZM3 A;  2C46 A;  2J17 A;  1OEO X;  5HDE A;  5KA4 A;  3CWE A;  2NT7 A;  5KAC A;  3QCC A;  3MOW A;  4J51 A;  1Q6P A;  4WU2 A;  1YPT A;  1ZCK A;  1Q6S A;  1X24 A;  3EMU A;  2CFV A;  1G7F A;  1OEV A;  4B04 A;  5BZZ A;  1G4W R;  3D1Q A;  1LAR A;  5KA9 A;  2I6M A;  3V0F A;  3ZM2 A;  1OET A;  1C85 A;  1L8G A;  1A5Y A;  1U24 A;  3OLR A;  2GP0 A;  1G1F A;  3QCF A;  3RGO A;  2HCM A;  2HB1 A;  3A5J A;  1J4X A;  4ZN5 A;  1C87 A;  4RH5 A;  5MMZ B;  2CNH A;  1Q6J A;  1PH0 A;  2YDU A;  3S3H A;  2H03 A;  3MOZ A;  2AZR A;  1ZCL A;  1FPR A;  1PA9 A;  2I6O A;  1GWZ A;  2I5X A;  4RHG A;  1C83 A;  3QCM A;  1Q6M A;  4RI4 A;  2P6X A;  2QBS A;  2CMA A;  2CM7 A;  4D3P A;  1Q6T A;  2OUD A;  5IBM A;  3D44 A;  2R0B A;  2OOQ A;  3F9A A;  2F6F A;  1C84 A;  1JLN A;  3A5K A;  5KAA A;  1ECV A;  5K9W A;  2VEU A;  1GFY A;  1T4J A;  3OMH A;  1U26 A;  1G1G A;  1ZZW A;  3CM3 A;  2WGP A;  4PYH A;  2Q47 A;  2I4G A;  2PT0 A;  2B49 A;  3BRH A;  5EHP A;  2F46 A;  4R30 A;  1EEN A;  2A8B A;  3D1H A;  3EB1 A;  2M3V A;  4GWF A;  2AHS A;  2I42 A;  1I57 A;  2B3O A;  2CMB A;  2F70 A;  4D3R A;  2Q05 A;  3N0A A;  4GS0 A;  1WCH A;  5BZX A;  2PBN A;  4NND A;  2HVL A;  2J16 B;  1YFO A;  4WU3 A;  1PYN A;  1NZ7 A;  2BIJ A;  1OEU A;  5KAB A;  4GE5 A;  3F9B A;  5M43 A;  3ZM0 A;  4OHH A;  4S0G A;  2GJT A;  2G59 A;  3O5X A;  1PTV A;  2I1Y A;  1PTT A;  4RH9 A;  2QEP A;  2F71 A;  1YTS A;  4PVG A;  2MBC A;  2CNI A;  2H02 A;  2NLK A;  4JMJ A;  2ESB A;  3BLU A;  2NT2 A;  2F6T A;  3ZMQ A;  1SUG A;  1MKP A;  4QAP A;  1YTW A;  2CNE A;  2F6Y A;  1FPZ A;  4ICZ A;  1AAX A;  1XXP A;  1G7G A;  2PA5 A;  2HC1 A;  4GRY A;  3ZM1 A;  1RPM A;  2FJM A;  4GE6 A;  5K25 A;  4ZRT A;  3QCL A;  4RI5 A;  2ZMM A;  4GFV A;  2H4V A;  1KAK A;  1OEM X;  1XBO A;  2HXP A;  2H4K A;  3S3K A;  1P15 A;  1YGR A;  3QCN A;  1ZC0 A;  4YAA A;  1QXK A;  2JJD A;  2P4D A;  1XRI A;  2DXP A;  2I6P A;  3F81 A;  1NWE A;  2NV5 A;  4DGX A;  4WOH A;  2OZ5 A;  4KYR A;  1I9T A;  2B4S A;  4Y2E A;  2QDC A;  4DGP A;  2B4U A;  2Y96 A;  4NWF A;  1LYV A;  1YGU A;  5BUG A;  4QUN A;  2QBP A;  5KA0 A;  2CM2 A;  1VHR A;  4NWG A;  4R0S A;  5LXQ B;  1OHE A;  3O4T A;  1M3G A;  1QZ0 A;  1Q1M A;  1T49 A;  3O4S A;  5KA7 A;  5K23 A;  2HNQ A;  4OHE A;  4R0T A;  2I3R A;  5EHR A;  3O3L A;  3V0H A;  4D3Q A;  3QCK A;  3RO1 A;  2CM3 A;  1ONY A;  3AWE A;  1WAX A;  2BGD A;  1G1H A;  4OHD A;  3MMJ A;  3QCD A;  1WRM A;  2B07 A;  1XXV A;  3V0D A;  3I7Z A;  1PA1 A;  2QDM A;  2HC2 A;  2VEW A;  3ZV2 A;  1Q6N A;  3LJ8 A;  4HRF A;  1BZJ A;  4JNB A;  1BZC A;  3AWG A;  3D42 A;  2CNG A;  5KA8 A;  4BJO A;  2GWO A;  5IBS A;  4IKC A;  2H4G A;  2J16 A;  2ZN7 A;  2CM8 A;  3M4U A;  2I3U A;  2VEX A;  3H2X A;  3GXG A;  2B4O A;  2F6Z A;  1T48 A;  4KYQ A;  1ONZ A;  1YWF A;  3QCB A;  4NYH A;  4TVV A;  1YTN A;  3V0G A;  5GTJ A;  2IMG A;  4RKK A;  4QAH A;  3SME A;  1FQ1 A;  2NTA A;  4BPC A;  3BLT A;  3AWF A;  4JBC A;  3QKQ A;  3EAX A;  1R6H A;  4HJP A;  4AZ1 A;  2G6Z A;  2BGE A;  1D5R A;  3S4O A;  2QCT A;  3B7O A;  2QBQ A;  1G4U S;  3D1O A;  4GE2 A;  3ZMP A;  2I4H A;  1NWL A;  4I8N A;  1BZH A;  4QBE A;  1NO6 A;  2SHP A;  4RDD A;  1OHC A;  2OC3 A; 
#chains in the Genus database with same CATH topology
 4OHL A;  3F99 A;  1P3D A;  4GFU A;  3V0J A;  2RF6 A;  4Y14 A;  3PS5 A;  2CNF A;  3QCG A;  4UAG A;  2PSZ A;  3S3E A;  1U25 A;  2QDP A;  3RGQ A;  4YR8 B;  1V3A A;  2QCJ A;  3I36 A;  5J8R A;  1YZ4 A;  1C86 A;  4KI9 A;  4Z6B A;  4WTY A;  1C88 A;  4JMK A;  1PTU A;  2PQ5 A;  3BM8 A;  2F00 A;  2I6J A;  2CMC A;  1PTY A;  4ERC A;  5K24 A;  1XM2 A;  4GRZ A;  2AM2 A;  5K9V A;  3EU0 A;  3ZM6 A;  2H04 A;  2E0T A;  2FH7 A;  4H34 A;  2VEY A;  1KAV A;  1NNY A;  2QBR A;  1W7K A;  3NME A;  1OES A;  2VOS A;  5KAD A;  3S4E A;  2AM1 A;  2UAG A;  4ZI4 A;  2I4E A;  1JF7 A;  5I6V A;  1E0D A;  1LQF A;  1YN9 A;  2CJZ A;  3EZZ A;  3D9C A;  4MBB A;  2BZL A;  2HY3 A;  3V0I A;  2F6W A;  1EEO A;  1OHD A;  5KA1 A;  1PXH A;  2I6I A;  3QKP A;  1UAG A;  2C7S A;  4QBW A;  3I80 A;  2HNP A;  5AWX A;  5BX1 A;  2NZ6 A;  3S3F A;  2PI7 A;  2B4P A;  2JFG A;  3QCE A;  4C12 A;  4QUM A;  1RXD A;  2VEV A;  2Y1O A;  2BV5 A;  3SR9 A;  2Y2F A;  3V0E A;  1O5Z A;  5K22 A;  3F41 A;  2F6V A;  3LK7 A;  5KA3 A;  3RZ2 A;  3O4U A;  2WJP A;  3QCH A;  4OHI A;  2GC6 A;  2VOR A;  5KA2 A;  1L8K A;  4HJQ A;  2FJN A;  3U96 A;  3QCJ A;  3QCI A;  2I75 A;  1I9S A;  1NL9 A;  4H1O A;  3GXH A;  2A3K A;  2GCA A;  2Y66 A;  4NX8 A;  3ZM3 A;  2C46 A;  2J17 A;  1OEO X;  5HDE A;  5KA4 A;  3CWE A;  2NT7 A;  5KAC A;  3QCC A;  3MOW A;  4J51 A;  1Q6P A;  4WU2 A;  1YPT A;  1ZCK A;  1Q6S A;  1X24 A;  3EMU A;  2CFV A;  1G7F A;  1OEV A;  4B04 A;  5BZZ A;  1G4W R;  3D1Q A;  1LAR A;  5KA9 A;  2I6M A;  2VTD A;  3V0F A;  3ZM2 A;  1OET A;  3MVN A;  1C85 A;  1L8G A;  1A5Y A;  1U24 A;  3OLR A;  2GP0 A;  4BUC A;  1G1F A;  3QCF A;  3RGO A;  2X5O A;  2HCM A;  2HB1 A;  3A5J A;  1J4X A;  2GC5 A;  4ZN5 A;  1C87 A;  4RH5 A;  5MMZ B;  2CNH A;  1Q6J A;  1PH0 A;  2YDU A;  3S3H A;  2H03 A;  3MOZ A;  2AZR A;  1ZCL A;  1FPR A;  1PA9 A;  2I6O A;  1GWZ A;  1EEH A;  2I5X A;  4RHG A;  1C83 A;  3NRS A;  1Q6M A;  3QCM A;  4RI4 A;  2P6X A;  2QBS A;  2CMA A;  5A5F A;  2CM7 A;  2VTE A;  3N2A A;  4D3P A;  1GQY A;  1Q6T A;  2OUD A;  5IBM A;  3D44 A;  2R0B A;  2OOQ A;  3F9A A;  2F6F A;  1C84 A;  1JLN A;  3A5K A;  5KAA A;  1ECV A;  5K9W A;  2VEU A;  1GFY A;  1T4J A;  3OMH A;  1U26 A;  1G1G A;  1ZZW A;  3CM3 A;  3HN7 A;  2WGP A;  4PYH A;  2Q47 A;  4CVK A;  2I4G A;  2PT0 A;  2B49 A;  3BRH A;  5EHP A;  2F46 A;  4R30 A;  1EEN A;  1P31 A;  2A8B A;  3D1H A;  3EB1 A;  3UAG A;  2M3V A;  4GWF A;  2AHS A;  2I42 A;  2GCB A;  1I57 A;  2B3O A;  2CMB A;  2F70 A;  4D3R A;  2Q05 A;  3N0A A;  4GS0 A;  1WCH A;  5BZX A;  5A5E A;  2PBN A;  4NND A;  2HVL A;  2J16 B;  1YFO A;  4WU3 A;  1PYN A;  1NZ7 A;  2BIJ A;  1OEU A;  5KAB A;  4GE5 A;  3F9B A;  5M43 A;  3ZM0 A;  4OHH A;  4S0G A;  2GJT A;  2G59 A;  3O5X A;  2UUO A;  1PTV A;  2I1Y A;  1PTT A;  4RH9 A;  2QEP A;  2F71 A;  4QDI A;  1YTS A;  4PVG A;  2XJA A;  2MBC A;  2CNI A;  4BUB A;  2H02 A;  2NLK A;  4JMJ A;  2ESB A;  3BLU A;  2NT2 A;  2F6T A;  3ZMQ A;  1SUG A;  3QCZ A;  1MKP A;  2Y68 A;  4QAP A;  1YTW A;  2CNE A;  2F6Y A;  1FPZ A;  4ICZ A;  1AAX A;  1XXP A;  1JBW A;  1G7G A;  2PA5 A;  3ZM5 A;  2HC1 A;  4GRY A;  3ZM1 A;  1RPM A;  2FJM A;  4GE6 A;  5K25 A;  4ZRT A;  3QCL A;  4RI5 A;  2ZMM A;  4GFV A;  2H4V A;  1KAK A;  1OEM X;  1XBO A;  2HXP A;  4CVM A;  2H4K A;  3S3K A;  1P15 A;  1YGR A;  3QCN A;  3ZL8 A;  1E8C A;  1ZC0 A;  4CVL A;  1GG4 A;  4YAA A;  1FGS A;  1QXK A;  2JJD A;  1GQQ A;  2WTZ A;  2P4D A;  1XRI A;  2DXP A;  2I6P A;  3F81 A;  1NWE A;  2NV5 A;  4DGX A;  4WOH A;  2OZ5 A;  4KYR A;  2JFH A;  1I9T A;  2B4S A;  4Y2E A;  2QDC A;  4DGP A;  2B4U A;  2Y96 A;  4NWF A;  1LYV A;  1YGU A;  5BUG A;  4QUN A;  2QBP A;  5KA0 A;  2CM2 A;  1VHR A;  4NWG A;  4R0S A;  5LXQ B;  1OHE A;  3O4T A;  1M3G A;  2JFF A;  1QZ0 A;  4ZIY A;  3PYZ A;  1Q1M A;  1T49 A;  3O4S A;  5KA7 A;  5K23 A;  2HNQ A;  4OHE A;  4R0T A;  2I3R A;  1J6U A;  5EHR A;  3O3L A;  3V0H A;  4D3Q A;  2Y67 A;  3QCK A;  3RO1 A;  2CM3 A;  1ONY A;  3AWE A;  1WAX A;  2BGD A;  1G1H A;  4OHD A;  3MMJ A;  3QCD A;  4HV4 A;  1WRM A;  2B07 A;  1XXV A;  3V0D A;  2XPC A;  3I7Z A;  4C13 A;  1PA1 A;  2QDM A;  1W78 A;  2HC2 A;  2VEW A;  3ZV2 A;  1Q6N A;  3LJ8 A;  4HRF A;  1BZJ A;  4JNB A;  1BZC A;  3AWG A;  3D42 A;  2CNG A;  5KA8 A;  4BJO A;  2GWO A;  5IBS A;  4IKC A;  2H4G A;  2J16 A;  2ZN7 A;  2CM8 A;  3M4U A;  2I3U A;  2VEX A;  3H2X A;  3GXG A;  2B4O A;  2F6Z A;  1T48 A;  2UUP A;  4KYQ A;  1ONZ A;  1JBV A;  1YWF A;  3QCB A;  4NYH A;  4TVV A;  1YTN A;  3V0G A;  5GTJ A;  2IMG A;  4RKK A;  4QAH A;  3SME A;  1FQ1 A;  2NTA A;  4BPC A;  4QF5 A;  3BLT A;  3AWF A;  4JBC A;  3QKQ A;  3EAX A;  1R6H A;  4HJP A;  4AZ1 A;  2G6Z A;  2BGE A;  1D5R A;  3S4O A;  2QCT A;  3B7O A;  2QBQ A;  1G4U S;  3D1O A;  4GE2 A;  3ZMP A;  2I4H A;  1NWL A;  4I8N A;  1BZH A;  4QBE A;  1NO6 A;  2SHP A;  4RDD A;  1OHC A;  2OC3 A; 
#chains in the Genus database with same CATH homology
 4OHL A;  3F99 A;  3V0J A;  4GFU A;  2RF6 A;  4Y14 A;  3PS5 A;  2CNF A;  3QCG A;  2PSZ A;  3S3E A;  1U25 A;  2QDP A;  3RGQ A;  4YR8 B;  1V3A A;  2QCJ A;  3I36 A;  5J8R A;  1YZ4 A;  1C86 A;  4KI9 A;  4Z6B A;  4WTY A;  1C88 A;  4JMK A;  1PTU A;  2PQ5 A;  3BM8 A;  2I6J A;  2CMC A;  1PTY A;  4ERC A;  5K24 A;  1XM2 A;  4GRZ A;  5K9V A;  3EU0 A;  2H04 A;  2E0T A;  2FH7 A;  4H34 A;  2VEY A;  1KAV A;  1NNY A;  2QBR A;  3NME A;  1OES A;  5KAD A;  3S4E A;  4ZI4 A;  2I4E A;  1JF7 A;  5I6V A;  1LQF A;  1YN9 A;  2CJZ A;  3EZZ A;  3D9C A;  4MBB A;  2BZL A;  2HY3 A;  3V0I A;  2F6W A;  1EEO A;  1OHD A;  5KA1 A;  1PXH A;  2I6I A;  3QKP A;  2C7S A;  4QBW A;  3I80 A;  2HNP A;  5AWX A;  5BX1 A;  2NZ6 A;  3S3F A;  2PI7 A;  2B4P A;  3QCE A;  4QUM A;  1RXD A;  2VEV A;  2BV5 A;  3SR9 A;  2Y2F A;  3V0E A;  5K22 A;  3F41 A;  2F6V A;  5KA3 A;  3RZ2 A;  3O4U A;  3QCH A;  4OHI A;  5KA2 A;  1L8K A;  4HJQ A;  2FJN A;  3U96 A;  3QCJ A;  3QCI A;  2I75 A;  1I9S A;  1NL9 A;  4H1O A;  3GXH A;  2A3K A;  4NX8 A;  3ZM3 A;  2C46 A;  2J17 A;  1OEO X;  5HDE A;  5KA4 A;  3CWE A;  2NT7 A;  5KAC A;  3QCC A;  3MOW A;  4J51 A;  1Q6P A;  4WU2 A;  1YPT A;  1ZCK A;  1Q6S A;  1X24 A;  3EMU A;  2CFV A;  1G7F A;  1OEV A;  4B04 A;  5BZZ A;  1G4W R;  3D1Q A;  1LAR A;  5KA9 A;  2I6M A;  3V0F A;  3ZM2 A;  1OET A;  1C85 A;  1L8G A;  1A5Y A;  1U24 A;  3OLR A;  2GP0 A;  1G1F A;  3QCF A;  3RGO A;  2HCM A;  2HB1 A;  3A5J A;  1J4X A;  4ZN5 A;  1C87 A;  4RH5 A;  5MMZ B;  2CNH A;  1Q6J A;  1PH0 A;  2YDU A;  3S3H A;  2H03 A;  3MOZ A;  2AZR A;  1ZCL A;  1FPR A;  1PA9 A;  2I6O A;  1GWZ A;  2I5X A;  4RHG A;  1C83 A;  3QCM A;  1Q6M A;  4RI4 A;  2P6X A;  2QBS A;  2CMA A;  2CM7 A;  4D3P A;  1Q6T A;  2OUD A;  5IBM A;  3D44 A;  2R0B A;  2OOQ A;  3F9A A;  2F6F A;  1C84 A;  1JLN A;  3A5K A;  5KAA A;  1ECV A;  5K9W A;  2VEU A;  1GFY A;  1T4J A;  3OMH A;  1U26 A;  1G1G A;  1ZZW A;  3CM3 A;  2WGP A;  4PYH A;  2Q47 A;  2I4G A;  2PT0 A;  2B49 A;  3BRH A;  5EHP A;  2F46 A;  4R30 A;  1EEN A;  2A8B A;  3D1H A;  3EB1 A;  2M3V A;  4GWF A;  2AHS A;  2I42 A;  1I57 A;  2B3O A;  2CMB A;  2F70 A;  4D3R A;  2Q05 A;  3N0A A;  4GS0 A;  1WCH A;  5BZX A;  2PBN A;  4NND A;  2HVL A;  2J16 B;  1YFO A;  4WU3 A;  1PYN A;  1NZ7 A;  2BIJ A;  1OEU A;  5KAB A;  4GE5 A;  3F9B A;  5M43 A;  3ZM0 A;  4OHH A;  4S0G A;  2GJT A;  2G59 A;  3O5X A;  1PTV A;  2I1Y A;  1PTT A;  4RH9 A;  2QEP A;  2F71 A;  1YTS A;  4PVG A;  2MBC A;  2CNI A;  2H02 A;  2NLK A;  4JMJ A;  2ESB A;  3BLU A;  2NT2 A;  2F6T A;  3ZMQ A;  1SUG A;  1MKP A;  4QAP A;  1YTW A;  2CNE A;  2F6Y A;  1FPZ A;  4ICZ A;  1AAX A;  1XXP A;  1G7G A;  2PA5 A;  2HC1 A;  4GRY A;  3ZM1 A;  1RPM A;  2FJM A;  4GE6 A;  5K25 A;  4ZRT A;  3QCL A;  4RI5 A;  2ZMM A;  4GFV A;  2H4V A;  1KAK A;  1OEM X;  1XBO A;  2HXP A;  2H4K A;  3S3K A;  1P15 A;  1YGR A;  3QCN A;  1ZC0 A;  4YAA A;  1QXK A;  2JJD A;  2P4D A;  1XRI A;  2DXP A;  2I6P A;  3F81 A;  1NWE A;  2NV5 A;  4DGX A;  4WOH A;  2OZ5 A;  4KYR A;  1I9T A;  2B4S A;  4Y2E A;  2QDC A;  4DGP A;  2B4U A;  2Y96 A;  4NWF A;  1LYV A;  1YGU A;  5BUG A;  4QUN A;  2QBP A;  5KA0 A;  2CM2 A;  1VHR A;  4NWG A;  4R0S A;  5LXQ B;  1OHE A;  3O4T A;  1M3G A;  1QZ0 A;  1Q1M A;  1T49 A;  3O4S A;  5KA7 A;  5K23 A;  2HNQ A;  4OHE A;  4R0T A;  2I3R A;  5EHR A;  3O3L A;  3V0H A;  4D3Q A;  3QCK A;  3RO1 A;  2CM3 A;  1ONY A;  3AWE A;  1WAX A;  2BGD A;  1G1H A;  4OHD A;  3MMJ A;  3QCD A;  1WRM A;  2B07 A;  1XXV A;  3V0D A;  3I7Z A;  1PA1 A;  2QDM A;  2HC2 A;  2VEW A;  3ZV2 A;  1Q6N A;  3LJ8 A;  4HRF A;  1BZJ A;  4JNB A;  1BZC A;  3AWG A;  3D42 A;  2CNG A;  5KA8 A;  4BJO A;  2GWO A;  5IBS A;  4IKC A;  2H4G A;  2J16 A;  2ZN7 A;  2CM8 A;  3M4U A;  2I3U A;  2VEX A;  3H2X A;  3GXG A;  2B4O A;  2F6Z A;  1T48 A;  4KYQ A;  1ONZ A;  1YWF A;  3QCB A;  4NYH A;  4TVV A;  1YTN A;  3V0G A;  5GTJ A;  2IMG A;  4RKK A;  4QAH A;  3SME A;  1FQ1 A;  2NTA A;  4BPC A;  3BLT A;  3AWF A;  4JBC A;  3QKQ A;  3EAX A;  1R6H A;  4HJP A;  4AZ1 A;  2G6Z A;  2BGE A;  1D5R A;  3S4O A;  2QCT A;  3B7O A;  2QBQ A;  1G4U S;  3D1O A;  4GE2 A;  3ZMP A;  2I4H A;  1NWL A;  4I8N A;  1BZH A;  4QBE A;  1NO6 A;  2SHP A;  4RDD A;  1OHC A;  2OC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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