1XNZA

Crystal structure of mn(ii) form of e. coli. methionine aminopeptidase in complex with 5-(2-chlorophenyl)furan-2-carboxylic acid
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Metalloform-Selective Inhibitors of Escherichia coli Methionine Aminopeptidase and X-ray Structure of a Mn(II)-Form Enzyme Complexed with an Inhibitor.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Escherichia coli
total genus 90
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-10-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1xnzA00
1QXZA 2GU4A 2P98A 5CE6A 2GU5A 1XGNA 4FLIA 4EGEA 2DFIA 4U75A 1B59A 2GG7A 2HOWA 2ZSGA 2GGBA 2Q94A 2GG3A 2EVOA 4A6VA 5CDVA 1R5GA 1XGSA 2BH3A 1Y1NA 4JUQA 2B3HA 3CB5A 3MR1A 4A6WA 2OAZA 4FLJA 2MATA 2B3KA 3RORA 4ZNGA 4U6EA 1KQ0A 3PKEA 3IU9A 5CDLA 1KP0A 2GZ5A 2GTXA 3MX6A 4S00A 4PV4A 4IDYA 1BOAA 1M35A 4PNCA 5D6FA 2GG2A 2EVMA 2GG9A 2P9AA 2V3XA 4R60A 4ZWPA 2GG8A 5JHUA 1XGMA 2BN7A 4FO8A 4U1BA 2V6CA 2V3YA 1YVMA 1WKMA 2GG0A 2V3ZA 3FMRA 2Q96A 1R58A 4IKSA 5CDEA 3RVAA 3L24A 3Q6DA 4RZYA 2NQ7A 1C22A 4IKRA 5D6EA 2BWXA 3BIPA 2Q92A 4U6CA 4OOKA 2Q93A 4FLLA 1YW9A 4Z7MA 1W7VA 4RGZ1 3MATA 4U6ZA 2GG5A 4S01A 1YJ3A 4U73A 1O0XA 4KM3A 5CIKA 2BHBA 2BWTA 2BWUA 1XNZA 1YW8A 1WY2A 1C27A 1MATA 1W2MA 2BWVA 1JAWA 5FCFA 3BIQA 4FKCA 5CLSA 5CNXA 3TB5A 2BWYA 4FLKA 1C21A 3CB6A 2B3LA 5E5BA 3PKAA 1N51A 4RZZA 1R5HA 4U6WA 4IF7A 1QZYA 4U70A 3TAVA 3PKDA 3FM3A 3CTZA 1WBQA 4IKUA 4HXXA 2ADUA 4B28A 1YW7A 3BITA 1WN1A 1WLRA 1C24A 2G6PA 3S6BA 5FCHA 2EA4A 4U6JA 1WL9A 2BWSA 3IG4A 4IKTA 4QR8A 2NQ6A 3IU8A 2BHCA 1WL6A 3IU7A 2EVCA 1QXYA 2GU6A 2Q95A 2GU7A 2GA2A 4ZWUA 3PKCA 4IU6A 4ZWOA 1BN5A 1C23A 4U69A 2BHDA 5JFRA 3FMQA 1B6AA 3PKBA 1KQ9A 4FUKA 4IPAA 4MATA 1PV9A 2OKNA 1CHMA 4FO7A 4S2TP 3L7GA 1QXWA 1XGOA 2IW2A 4U71A 2BHAA 1A16A 2BWWA 2EA2A 4IECA 2P99A 3D27A 2Q8KA 2BB7A 2GGCA 4U76A 5JI6A 4S2RP
chains in the Genus database with same CATH superfamily
1QXZA 2GU4A 2P98A 5CE6A 2GU5A 1XGNA 4FLIA 4EGEA 2DFIA 4U75A 1B59A 2GG7A 2HOWA 2ZSGA 2GGBA 2Q94A 2GG3A 2EVOA 4A6VA 5CDVA 1R5GA 1XGSA 2BH3A 1Y1NA 4JUQA 2B3HA 3CB5A 3MR1A 4A6WA 2OAZA 4FLJA 2MATA 2B3KA 3RORA 4ZNGA 4U6EA 1KQ0A 3PKEA 3IU9A 5CDLA 1KP0A 2GZ5A 2GTXA 3MX6A 4S00A 4PV4A 4IDYA 1BOAA 1M35A 4PNCA 5D6FA 2GG2A 2EVMA 2GG9A 2P9AA 2V3XA 4R60A 4ZWPA 2GG8A 5JHUA 1XGMA 2BN7A 4FO8A 4U1BA 2V6CA 2V3YA 1YVMA 1WKMA 2GG0A 2V3ZA 3FMRA 2Q96A 1R58A 4IKSA 5CDEA 3RVAA 3L24A 3Q6DA 4RZYA 2NQ7A 1C22A 4IKRA 5D6EA 2BWXA 3BIPA 2Q92A 4U6CA 4OOKA 2Q93A 4FLLA 1YW9A 4Z7MA 1W7VA 4RGZ1 3MATA 4U6ZA 2GG5A 4S01A 1YJ3A 4U73A 1O0XA 4KM3A 5CIKA 2BHBA 2BWTA 2BWUA 1XNZA 1YW8A 1WY2A 1C27A 1MATA 1W2MA 2BWVA 1JAWA 5FCFA 3BIQA 4FKCA 5CLSA 5CNXA 3TB5A 2BWYA 4FLKA 1C21A 3CB6A 2B3LA 5E5BA 3PKAA 1N51A 4RZZA 1R5HA 4U6WA 4IF7A 1QZYA 4U70A 3TAVA 3PKDA 3FM3A 3CTZA 1WBQA 4IKUA 4HXXA 2ADUA 4B28A 1YW7A 3BITA 1WN1A 1WLRA 1C24A 2G6PA 3S6BA 5FCHA 2EA4A 4U6JA 1WL9A 2BWSA 3IG4A 4IKTA 4QR8A 2NQ6A 3IU8A 2BHCA 1WL6A 3IU7A 2EVCA 1QXYA 2GU6A 2Q95A 2GU7A 2GA2A 4ZWUA 3PKCA 4IU6A 4ZWOA 1BN5A 1C23A 4U69A 2BHDA 5JFRA 3FMQA 1B6AA 3PKBA 1KQ9A 4FUKA 4IPAA 4MATA 1PV9A 2OKNA 1CHMA 4FO7A 4S2TP 3L7GA 1QXWA 1XGOA 2IW2A 4U71A 2BHAA 1A16A 2BWWA 2EA2A 4IECA 2P99A 3D27A 2Q8KA 2BB7A 2GGCA 4U76A 5JI6A 4S2RP
chains in the Genus database with same CATH topology
1QXZA 2GU4A 2P98A 5CE6A 2GU5A 1XGNA 4FLIA 4EGEA 2DFIA 4U75A 1B59A 2GG7A 2HOWA 2ZSGA 2GGBA 2Q94A 2GG3A 2EVOA 4A6VA 5CDVA 1R5GA 1XGSA 2BH3A 1Y1NA 4JUQA 2B3HA 3CB5A 3MR1A 4A6WA 2OAZA 4FLJA 2MATA 2B3KA 3RORA 4ZNGA 4U6EA 1KQ0A 3PKEA 3IU9A 5CDLA 1KP0A 2GZ5A 2GTXA 3MX6A 4S00A 4PV4A 4IDYA 1BOAA 1M35A 4PNCA 5D6FA 2GG2A 2EVMA 2GG9A 2P9AA 2V3XA 4R60A 4ZWPA 2GG8A 5JHUA 1XGMA 2BN7A 4FO8A 4U1BA 2V6CA 2V3YA 1YVMA 1WKMA 2GG0A 2V3ZA 3FMRA 2Q96A 1R58A 4IKSA 5CDEA 3RVAA 3L24A 3Q6DA 4RZYA 2NQ7A 1C22A 4IKRA 5D6EA 2BWXA 3BIPA 2Q92A 4U6CA 4OOKA 2Q93A 4FLLA 1YW9A 4Z7MA 1W7VA 4RGZ1 3MATA 4U6ZA 2GG5A 4S01A 1YJ3A 4U73A 1O0XA 4KM3A 5CIKA 2BHBA 2BWTA 2BWUA 1XNZA 1YW8A 1WY2A 1C27A 1MATA 1W2MA 2BWVA 1JAWA 5FCFA 3BIQA 4FKCA 5CLSA 5CNXA 3TB5A 2BWYA 4FLKA 1C21A 3CB6A 2B3LA 5E5BA 3PKAA 1N51A 4RZZA 1R5HA 4U6WA 4IF7A 1QZYA 4U70A 3TAVA 3PKDA 3FM3A 3CTZA 1WBQA 4IKUA 4HXXA 2ADUA 4B28A 1YW7A 3BITA 1WN1A 1WLRA 1C24A 2G6PA 3S6BA 5FCHA 2EA4A 4U6JA 1WL9A 2BWSA 3IG4A 4IKTA 4QR8A 2NQ6A 3IU8A 2BHCA 1WL6A 3IU7A 2EVCA 1QXYA 2GU6A 2Q95A 2GU7A 2GA2A 4ZWUA 3PKCA 4IU6A 4ZWOA 1BN5A 1C23A 4U69A 2BHDA 5JFRA 3FMQA 1B6AA 3PKBA 1KQ9A 4FUKA 4IPAA 4MATA 1PV9A 2OKNA 1CHMA 4FO7A 4S2TP 3L7GA 1QXWA 1XGOA 2IW2A 4U71A 2BHAA 1A16A 2BWWA 2EA2A 4IECA 2P99A 3D27A 2Q8KA 2BB7A 2GGCA 4U76A 5JI6A 4S2RP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QXZ A;  2GU4 A;  2P98 A;  5CE6 A;  2GU5 A;  1XGN A;  4FLI A;  4EGE A;  2DFI A;  4U75 A;  1B59 A;  2GG7 A;  2HOW A;  2ZSG A;  2GGB A;  2Q94 A;  2GG3 A;  2EVO A;  4A6V A;  5CDV A;  1R5G A;  1XGS A;  2BH3 A;  1Y1N A;  4JUQ A;  2B3H A;  3CB5 A;  3MR1 A;  4A6W A;  2OAZ A;  4FLJ A;  2MAT A;  2B3K A;  3ROR A;  4ZNG A;  4U6E A;  1KQ0 A;  3PKE A;  3IU9 A;  5CDL A;  1KP0 A;  2GZ5 A;  2GTX A;  3MX6 A;  4S00 A;  4PV4 A;  4IDY A;  1BOA A;  1M35 A;  4PNC A;  5D6F A;  2GG2 A;  2EVM A;  2GG9 A;  2P9A A;  2V3X A;  4R60 A;  4ZWP A;  2GG8 A;  5JHU A;  1XGM A;  2BN7 A;  4FO8 A;  4U1B A;  2V6C A;  2V3Y A;  1YVM A;  1WKM A;  2GG0 A;  2V3Z A;  3FMR A;  2Q96 A;  1R58 A;  4IKS A;  5CDE A;  3RVA A;  3L24 A;  3Q6D A;  4RZY A;  2NQ7 A;  1C22 A;  4IKR A;  5D6E A;  2BWX A;  3BIP A;  2Q92 A;  4U6C A;  4OOK A;  2Q93 A;  4FLL A;  1YW9 A;  4Z7M A;  1W7V A;  4RGZ 1;  3MAT A;  4U6Z A;  2GG5 A;  4S01 A;  1YJ3 A;  4U73 A;  1O0X A;  4KM3 A;  5CIK A;  2BHB A;  2BWT A;  2BWU A;  1XNZ A;  1YW8 A;  1WY2 A;  1C27 A;  1MAT A;  1W2M A;  2BWV A;  1JAW A;  5FCF A;  3BIQ A;  4FKC A;  5CLS A;  5CNX A;  3TB5 A;  2BWY A;  4FLK A;  1C21 A;  3CB6 A;  2B3L A;  5E5B A;  3PKA A;  1N51 A;  4RZZ A;  1R5H A;  4U6W A;  4IF7 A;  1QZY A;  4U70 A;  3TAV A;  3PKD A;  3FM3 A;  3CTZ A;  1WBQ A;  4IKU A;  4HXX A;  2ADU A;  4B28 A;  1YW7 A;  3BIT A;  1WN1 A;  1WLR A;  1C24 A;  2G6P A;  3S6B A;  5FCH A;  2EA4 A;  4U6J A;  1WL9 A;  2BWS A;  3IG4 A;  4IKT A;  4QR8 A;  2NQ6 A;  3IU8 A;  2BHC A;  1WL6 A;  3IU7 A;  2EVC A;  1QXY A;  2GU6 A;  2Q95 A;  2GU7 A;  2GA2 A;  4ZWU A;  3PKC A;  4IU6 A;  4ZWO A;  1BN5 A;  1C23 A;  4U69 A;  2BHD A;  5JFR A;  3FMQ A;  1B6A A;  3PKB A;  1KQ9 A;  4FUK A;  4IPA A;  4MAT A;  1PV9 A;  2OKN A;  1CHM A;  4FO7 A;  4S2T P;  3L7G A;  1QXW A;  1XGO A;  2IW2 A;  4U71 A;  2BHA A;  1A16 A;  2BWW A;  2EA2 A;  4IEC A;  2P99 A;  3D27 A;  2Q8K A;  2BB7 A;  2GGC A;  4U76 A;  5JI6 A;  4S2R P; 
#chains in the Genus database with same CATH topology
 1QXZ A;  2GU4 A;  2P98 A;  5CE6 A;  2GU5 A;  1XGN A;  4FLI A;  4EGE A;  2DFI A;  4U75 A;  1B59 A;  2GG7 A;  2HOW A;  2ZSG A;  2GGB A;  2Q94 A;  2GG3 A;  2EVO A;  4A6V A;  5CDV A;  1R5G A;  1XGS A;  2BH3 A;  1Y1N A;  4JUQ A;  2B3H A;  3CB5 A;  3MR1 A;  4A6W A;  2OAZ A;  4FLJ A;  2MAT A;  2B3K A;  3ROR A;  4ZNG A;  4U6E A;  1KQ0 A;  3PKE A;  3IU9 A;  5CDL A;  1KP0 A;  2GZ5 A;  2GTX A;  3MX6 A;  4S00 A;  4PV4 A;  4IDY A;  1BOA A;  1M35 A;  4PNC A;  5D6F A;  2GG2 A;  2EVM A;  2GG9 A;  2P9A A;  2V3X A;  4R60 A;  4ZWP A;  2GG8 A;  5JHU A;  1XGM A;  2BN7 A;  4FO8 A;  4U1B A;  2V6C A;  2V3Y A;  1YVM A;  1WKM A;  2GG0 A;  2V3Z A;  3FMR A;  2Q96 A;  1R58 A;  4IKS A;  5CDE A;  3RVA A;  3L24 A;  3Q6D A;  4RZY A;  2NQ7 A;  1C22 A;  4IKR A;  5D6E A;  2BWX A;  3BIP A;  2Q92 A;  4U6C A;  4OOK A;  2Q93 A;  4FLL A;  1YW9 A;  4Z7M A;  1W7V A;  4RGZ 1;  3MAT A;  4U6Z A;  2GG5 A;  4S01 A;  1YJ3 A;  4U73 A;  1O0X A;  4KM3 A;  5CIK A;  2BHB A;  2BWT A;  2BWU A;  1XNZ A;  1YW8 A;  1WY2 A;  1C27 A;  1MAT A;  1W2M A;  2BWV A;  1JAW A;  5FCF A;  3BIQ A;  4FKC A;  5CLS A;  5CNX A;  3TB5 A;  2BWY A;  4FLK A;  1C21 A;  3CB6 A;  2B3L A;  5E5B A;  3PKA A;  1N51 A;  4RZZ A;  1R5H A;  4U6W A;  4IF7 A;  1QZY A;  4U70 A;  3TAV A;  3PKD A;  3FM3 A;  3CTZ A;  1WBQ A;  4IKU A;  4HXX A;  2ADU A;  4B28 A;  1YW7 A;  3BIT A;  1WN1 A;  1WLR A;  1C24 A;  2G6P A;  3S6B A;  5FCH A;  2EA4 A;  4U6J A;  1WL9 A;  2BWS A;  3IG4 A;  4IKT A;  4QR8 A;  2NQ6 A;  3IU8 A;  2BHC A;  1WL6 A;  3IU7 A;  2EVC A;  1QXY A;  2GU6 A;  2Q95 A;  2GU7 A;  2GA2 A;  4ZWU A;  3PKC A;  4IU6 A;  4ZWO A;  1BN5 A;  1C23 A;  4U69 A;  2BHD A;  5JFR A;  3FMQ A;  1B6A A;  3PKB A;  1KQ9 A;  4FUK A;  4IPA A;  4MAT A;  1PV9 A;  2OKN A;  1CHM A;  4FO7 A;  4S2T P;  3L7G A;  1QXW A;  1XGO A;  2IW2 A;  4U71 A;  2BHA A;  1A16 A;  2BWW A;  2EA2 A;  4IEC A;  2P99 A;  3D27 A;  2Q8K A;  2BB7 A;  2GGC A;  4U76 A;  5JI6 A;  4S2R P; 
#chains in the Genus database with same CATH homology
 1QXZ A;  2GU4 A;  2P98 A;  5CE6 A;  2GU5 A;  1XGN A;  4FLI A;  4EGE A;  2DFI A;  4U75 A;  1B59 A;  2GG7 A;  2HOW A;  2ZSG A;  2GGB A;  2Q94 A;  2GG3 A;  2EVO A;  4A6V A;  5CDV A;  1R5G A;  1XGS A;  2BH3 A;  1Y1N A;  4JUQ A;  2B3H A;  3CB5 A;  3MR1 A;  4A6W A;  2OAZ A;  4FLJ A;  2MAT A;  2B3K A;  3ROR A;  4ZNG A;  4U6E A;  1KQ0 A;  3PKE A;  3IU9 A;  5CDL A;  1KP0 A;  2GZ5 A;  2GTX A;  3MX6 A;  4S00 A;  4PV4 A;  4IDY A;  1BOA A;  1M35 A;  4PNC A;  5D6F A;  2GG2 A;  2EVM A;  2GG9 A;  2P9A A;  2V3X A;  4R60 A;  4ZWP A;  2GG8 A;  5JHU A;  1XGM A;  2BN7 A;  4FO8 A;  4U1B A;  2V6C A;  2V3Y A;  1YVM A;  1WKM A;  2GG0 A;  2V3Z A;  3FMR A;  2Q96 A;  1R58 A;  4IKS A;  5CDE A;  3RVA A;  3L24 A;  3Q6D A;  4RZY A;  2NQ7 A;  1C22 A;  4IKR A;  5D6E A;  2BWX A;  3BIP A;  2Q92 A;  4U6C A;  4OOK A;  2Q93 A;  4FLL A;  1YW9 A;  4Z7M A;  1W7V A;  4RGZ 1;  3MAT A;  4U6Z A;  2GG5 A;  4S01 A;  1YJ3 A;  4U73 A;  1O0X A;  4KM3 A;  5CIK A;  2BHB A;  2BWT A;  2BWU A;  1XNZ A;  1YW8 A;  1WY2 A;  1C27 A;  1MAT A;  1W2M A;  2BWV A;  1JAW A;  5FCF A;  3BIQ A;  4FKC A;  5CLS A;  5CNX A;  3TB5 A;  2BWY A;  4FLK A;  1C21 A;  3CB6 A;  2B3L A;  5E5B A;  3PKA A;  1N51 A;  4RZZ A;  1R5H A;  4U6W A;  4IF7 A;  1QZY A;  4U70 A;  3TAV A;  3PKD A;  3FM3 A;  3CTZ A;  1WBQ A;  4IKU A;  4HXX A;  2ADU A;  4B28 A;  1YW7 A;  3BIT A;  1WN1 A;  1WLR A;  1C24 A;  2G6P A;  3S6B A;  5FCH A;  2EA4 A;  4U6J A;  1WL9 A;  2BWS A;  3IG4 A;  4IKT A;  4QR8 A;  2NQ6 A;  3IU8 A;  2BHC A;  1WL6 A;  3IU7 A;  2EVC A;  1QXY A;  2GU6 A;  2Q95 A;  2GU7 A;  2GA2 A;  4ZWU A;  3PKC A;  4IU6 A;  4ZWO A;  1BN5 A;  1C23 A;  4U69 A;  2BHD A;  5JFR A;  3FMQ A;  1B6A A;  3PKB A;  1KQ9 A;  4FUK A;  4IPA A;  4MAT A;  1PV9 A;  2OKN A;  1CHM A;  4FO7 A;  4S2T P;  3L7G A;  1QXW A;  1XGO A;  2IW2 A;  4U71 A;  2BHA A;  1A16 A;  2BWW A;  2EA2 A;  4IEC A;  2P99 A;  3D27 A;  2Q8K A;  2BB7 A;  2GGC A;  4U76 A;  5JI6 A;  4S2R P; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...