1XQOA

Crystal structure of native pa-agog, 8-oxoguanine dna glycosylase from pyrobaculum aerophilum
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
253
structure length
253
Chain Sequence
AAESQLKRVIETLRRLGIEEVLKLERRDPQYRAVCNVVKRHGETVGSRLAMLNALISYRLTGKGEEHWEYFGKYFSQLEVIDLCRDFLKYIETSPFLKIGVEARKKRALKACDYVPNLEDLGLTLRQLSHIVGARREQKTLVFTIKILNYAYMCSRGVNRVLPFDIPIPVDYRVARLTWCAGLIDFPPEEALRRYEAVQKIWDAVARETGIPPLHLDTLLWLAGRAVLYGENLHGVPKEVIALFQWRGGCRPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure
pubmed doi rcsb
molecule tags Lyase
source organism Pyrobaculum aerophilum
molecule keywords 8-oxoguanine DNA glycosylase
total genus 98
structure length 253
sequence length 253
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09171 AGOG N-glycosylase/DNA lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1xqoA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1xqoA01
4B21A 1PU7A 4B23A 4YPRA 2NOLA 1VRLA 1MUYA 1WEIA 4YPHA 1M3QA 1KG6A 1XQOA 4EW4A 4EJZA 5CHZA 2NOHA 4HSBA 3F10A 2H56A 1PVSA 4UOBA 1DIZA 1NGNA 1KG7A 3N5NX 1LWVA 2NOEA 4AI5A 1YQLA 3IHOA 4OFAA 3FSPA 1XQPA 1RRSA 1NKUA 4B24A 1N3AA 3CWSA 3I0WA 2I5WA 1MUDA 1YQMA 1M3HA 4B22A 1KO9A 1ORNA 1YQKA 1YQRA 4E9FA 1MUNA 2JG6A 1LWWA 2NOZA 1WEFA 1PU6A 4YOQA 1MPGA 3OH9A 4E9HA 2JHJA 3CVSA 1KG2A 1LWYA 2NOIA 4UNFA 1PU8A 4AI4A 1EBMA 4OFHA 3G0QA 5AN4A 3CWTA 1KG5A 2YG9A 3FHFA 4DK9A 1LMZA 3CWAA 3CW7A 3IH7A 1XG7A 3KNTA 3I0XA 4EJYA 4OFEA 1KG4A 2JHNA 3CWUA 4EA5A 1HU0A 5DPKA 1KG3A 2ABKA 3CVTA 2XHIA 4E9GA 5KN9A 3OH6A 1N39A 4EW0A 2OFKA 2YG8A 5KN8A 4EA4A 1FN7A 2OFIA 4E9EA 3OGDA 3S6IA 3KTUA 1KQJA 2NOBA 1KEAA 1P7MA 3N0UA 1P59A 4EVVA 1RRQA 4AIAA 3F0ZA 1WEGA 1ORPA 3D4VA 1N3CA 2NOFA 3FHGA 4PIIA
chains in the Genus database with same CATH superfamily
3S3OA 4B21A 1PU7A 4B23A 4YPRA 4ZTJA 1VRLA 2NOLA 4E7KA 3OYMA 1MUYA 1WEIA 4YPHA 1M3QA 1KG6A 1XQOA 4EW4A 3S3MA 5CHZA 4EJZA 2NOHA 3S3NA 4HSBA 3L2QA 3F10A 2H56A 3VW4A 1PVSA 3L2UA 4UOBA 1DIZA 1NGNA 2V75A 3OYBA 1KG7A 3N5NX 4E7JA 1LWVA 2NOEA 4AI5A 5FRNA 1YQLA 3OYCA 3IHOA 4OFAA 3FSPA 1XQPA 1RRSA 4BE0A 1NKUA 4B24A 2W03A 1N3AA 3CWSA 3I0WA 2I5WA 1MUDA 3OYDA 4NZGA 1YQMA 1M3HA 3OYFA 4E7IA 4B22A 4E7LA 1KO9A 1ORNA 4BDYA 2JPSA 1YQKA 1YQRA 4E9FA 1MUNA 2JG6A 1LWWA 2NOZA 1WEFA 1PU6A 4YOQA 1MPGA 4BDZA 3OS1A 3OH9A 4E9HA 2JHJA 4ZTFA 3OYIA 3CVSA 3NNQA 1KG2A 1LWYA 2NOIA 4UNFA 1PU8A 3L2VA 4AI4A 1EBMA 3OYKA 3OYLA 4OFHA 3G0QA 3OYAA 5AN4A 3CWTA 3L2RA 1KG5A 2YG9A 3OYEA 3FHFA 4DK9A 1LMZA 3CWAA 3OY9A 3CW7A 3IH7A 1XG7A 3KNTA 4E7HA 4BACA 3I0XA 4EJYA 4OFEA 3OS0A 4IKFA 1KG4A 3LCNA 2JHNA 3CWUA 4EA5A 1HU0A 5DPKA 2W04A 1KG3A 4BE1A 2ABKA 3CVTA 3L2WA 2XHIA 4E9GA 5KN9A 3OH6A 1N39A 5FROA 3OYHA 4EW0A 2OFKA 2YG8A 5KN8A 4EA4A 1FN7A 2OFIA 4E9EA 3OGDA 4BE2A 3KTUA 3S6IA 1KQJA 2NOBA 1KEAA 1P7MA 3N0UA 1P59A 4EVVA 1RRQA 4AIAA 3OYGA 3F0ZA 1WEGA 3R2XC 1ORPA 1U84A 3OYNA 3D4VA 1N3CA 2NOFA 3OYJA 3OS2A 3FHGA 5FRMA 4PIIA
chains in the Genus database with same CATH topology
4B21A 1PU7A 4B23A 4YPRA 2NOLA 1VRLA 1MUYA 1WEIA 4YPHA 1M3QA 1KG6A 1XQOA 4EW4A 4EJZA 5CHZA 2NOHA 4HSBA 3F10A 2H56A 1PVSA 4UOBA 1DIZA 1NGNA 1KG7A 3N5NX 1LWVA 2NOEA 4AI5A 1YQLA 3IHOA 4OFAA 3FSPA 1XQPA 1RRSA 1NKUA 4B24A 1N3AA 3CWSA 3I0WA 2I5WA 1MUDA 1YQMA 1M3HA 4B22A 1KO9A 1ORNA 1YQKA 1YQRA 4E9FA 1MUNA 2JG6A 1LWWA 2NOZA 1WEFA 1PU6A 4YOQA 1MPGA 3OH9A 4E9HA 2JHJA 3CVSA 1KG2A 1LWYA 2NOIA 4UNFA 1PU8A 4AI4A 1EBMA 4OFHA 3G0QA 5AN4A 3CWTA 1KG5A 2YG9A 3FHFA 4DK9A 1LMZA 3CWAA 3CW7A 3IH7A 1XG7A 3KNTA 3I0XA 4EJYA 4OFEA 1KG4A 2JHNA 3CWUA 4EA5A 1HU0A 5DPKA 1KG3A 2ABKA 3CVTA 2XHIA 4E9GA 5KN9A 3OH6A 1N39A 4EW0A 2OFKA 2YG8A 5KN8A 4EA4A 1FN7A 2OFIA 4E9EA 3OGDA 3S6IA 3KTUA 1KQJA 2NOBA 1KEAA 1P7MA 3N0UA 1P59A 4EVVA 1RRQA 4AIAA 3F0ZA 1WEGA 1ORPA 3D4VA 1N3CA 2NOFA 3FHGA 4PIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B21 A;  1PU7 A;  4B23 A;  4YPR A;  2NOL A;  1VRL A;  1MUY A;  1WEI A;  4YPH A;  1M3Q A;  1KG6 A;  1XQO A;  4EW4 A;  4EJZ A;  5CHZ A;  2NOH A;  4HSB A;  3F10 A;  2H56 A;  1PVS A;  4UOB A;  1DIZ A;  1NGN A;  1KG7 A;  3N5N X;  1LWV A;  2NOE A;  4AI5 A;  1YQL A;  3IHO A;  4OFA A;  3FSP A;  1XQP A;  1RRS A;  1NKU A;  4B24 A;  1N3A A;  3CWS A;  3I0W A;  2I5W A;  1MUD A;  1YQM A;  1M3H A;  4B22 A;  1KO9 A;  1ORN A;  1YQK A;  1YQR A;  4E9F A;  1MUN A;  2JG6 A;  1LWW A;  2NOZ A;  1WEF A;  1PU6 A;  4YOQ A;  1MPG A;  3OH9 A;  4E9H A;  2JHJ A;  3CVS A;  1KG2 A;  1LWY A;  2NOI A;  4UNF A;  1PU8 A;  4AI4 A;  1EBM A;  4OFH A;  3G0Q A;  5AN4 A;  3CWT A;  1KG5 A;  2YG9 A;  3FHF A;  4DK9 A;  1LMZ A;  3CWA A;  3CW7 A;  3IH7 A;  1XG7 A;  3KNT A;  3I0X A;  4EJY A;  4OFE A;  1KG4 A;  2JHN A;  3CWU A;  4EA5 A;  1HU0 A;  5DPK A;  1KG3 A;  2ABK A;  3CVT A;  2XHI A;  4E9G A;  5KN9 A;  3OH6 A;  1N39 A;  4EW0 A;  2OFK A;  2YG8 A;  5KN8 A;  4EA4 A;  1FN7 A;  2OFI A;  4E9E A;  3OGD A;  3S6I A;  3KTU A;  1KQJ A;  2NOB A;  1KEA A;  1P7M A;  3N0U A;  1P59 A;  4EVV A;  1RRQ A;  4AIA A;  3F0Z A;  1WEG A;  1ORP A;  3D4V A;  1N3C A;  2NOF A;  3FHG A;  4PII A; 
#chains in the Genus database with same CATH topology
 3S3O A;  4B21 A;  1PU7 A;  4B23 A;  4YPR A;  4ZTJ A;  1VRL A;  2NOL A;  4E7K A;  3OYM A;  1MUY A;  1WEI A;  4YPH A;  1M3Q A;  1KG6 A;  1XQO A;  4EW4 A;  3S3M A;  5CHZ A;  4EJZ A;  2NOH A;  3S3N A;  4HSB A;  3L2Q A;  3F10 A;  2H56 A;  3VW4 A;  1PVS A;  3L2U A;  4UOB A;  1DIZ A;  1NGN A;  2V75 A;  3OYB A;  1KG7 A;  3N5N X;  4E7J A;  1LWV A;  2NOE A;  4AI5 A;  5FRN A;  1YQL A;  3OYC A;  3IHO A;  4OFA A;  3FSP A;  1XQP A;  1RRS A;  4BE0 A;  1NKU A;  4B24 A;  2W03 A;  1N3A A;  3CWS A;  3I0W A;  2I5W A;  1MUD A;  3OYD A;  4NZG A;  1YQM A;  1M3H A;  3OYF A;  4E7I A;  4B22 A;  4E7L A;  1KO9 A;  1ORN A;  4BDY A;  2JPS A;  1YQK A;  1YQR A;  4E9F A;  1MUN A;  2JG6 A;  1LWW A;  2NOZ A;  1WEF A;  1PU6 A;  4YOQ A;  1MPG A;  4BDZ A;  3OS1 A;  3OH9 A;  4E9H A;  2JHJ A;  4ZTF A;  3OYI A;  3CVS A;  3NNQ A;  1KG2 A;  1LWY A;  2NOI A;  4UNF A;  1PU8 A;  3L2V A;  4AI4 A;  1EBM A;  3OYK A;  3OYL A;  4OFH A;  3G0Q A;  3OYA A;  5AN4 A;  3CWT A;  3L2R A;  1KG5 A;  2YG9 A;  3OYE A;  3FHF A;  4DK9 A;  1LMZ A;  3CWA A;  3OY9 A;  3CW7 A;  3IH7 A;  1XG7 A;  3KNT A;  4E7H A;  4BAC A;  3I0X A;  4EJY A;  4OFE A;  3OS0 A;  4IKF A;  1KG4 A;  3LCN A;  2JHN A;  3CWU A;  4EA5 A;  1HU0 A;  5DPK A;  2W04 A;  1KG3 A;  4BE1 A;  2ABK A;  3CVT A;  3L2W A;  2XHI A;  4E9G A;  5KN9 A;  3OH6 A;  1N39 A;  5FRO A;  3OYH A;  4EW0 A;  2OFK A;  2YG8 A;  5KN8 A;  4EA4 A;  1FN7 A;  2OFI A;  4E9E A;  3OGD A;  4BE2 A;  3KTU A;  3S6I A;  1KQJ A;  2NOB A;  1KEA A;  1P7M A;  3N0U A;  1P59 A;  4EVV A;  1RRQ A;  4AIA A;  3OYG A;  3F0Z A;  1WEG A;  3R2X C;  1ORP A;  1U84 A;  3OYN A;  3D4V A;  1N3C A;  2NOF A;  3OYJ A;  3OS2 A;  3FHG A;  5FRM A;  4PII A; 
#chains in the Genus database with same CATH homology
 4B21 A;  1PU7 A;  4B23 A;  4YPR A;  2NOL A;  1VRL A;  1MUY A;  1WEI A;  4YPH A;  1M3Q A;  1KG6 A;  1XQO A;  4EW4 A;  4EJZ A;  5CHZ A;  2NOH A;  4HSB A;  3F10 A;  2H56 A;  1PVS A;  4UOB A;  1DIZ A;  1NGN A;  1KG7 A;  3N5N X;  1LWV A;  2NOE A;  4AI5 A;  1YQL A;  3IHO A;  4OFA A;  3FSP A;  1XQP A;  1RRS A;  1NKU A;  4B24 A;  1N3A A;  3CWS A;  3I0W A;  2I5W A;  1MUD A;  1YQM A;  1M3H A;  4B22 A;  1KO9 A;  1ORN A;  1YQK A;  1YQR A;  4E9F A;  1MUN A;  2JG6 A;  1LWW A;  2NOZ A;  1WEF A;  1PU6 A;  4YOQ A;  1MPG A;  3OH9 A;  4E9H A;  2JHJ A;  3CVS A;  1KG2 A;  1LWY A;  2NOI A;  4UNF A;  1PU8 A;  4AI4 A;  1EBM A;  4OFH A;  3G0Q A;  5AN4 A;  3CWT A;  1KG5 A;  2YG9 A;  3FHF A;  4DK9 A;  1LMZ A;  3CWA A;  3CW7 A;  3IH7 A;  1XG7 A;  3KNT A;  3I0X A;  4EJY A;  4OFE A;  1KG4 A;  2JHN A;  3CWU A;  4EA5 A;  1HU0 A;  5DPK A;  1KG3 A;  2ABK A;  3CVT A;  2XHI A;  4E9G A;  5KN9 A;  3OH6 A;  1N39 A;  4EW0 A;  2OFK A;  2YG8 A;  5KN8 A;  4EA4 A;  1FN7 A;  2OFI A;  4E9E A;  3OGD A;  3S6I A;  3KTU A;  1KQJ A;  2NOB A;  1KEA A;  1P7M A;  3N0U A;  1P59 A;  4EVV A;  1RRQ A;  4AIA A;  3F0Z A;  1WEG A;  1ORP A;  3D4V A;  1N3C A;  2NOF A;  3FHG A;  4PII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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