1Y1EX

Human formylglycine generating enzyme
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
286
structure length
272
Chain Sequence
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMCHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords C-alpha-formyglycine-generating enzyme
publication title Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme.
pubmed doi rcsb
source organism Homo sapiens
total genus 79
structure length 272
sequence length 286
ec nomenclature ec 1.8.3.7: Formylglycine-generating enzyme.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03781 FGE-sulfatase Sulfatase-modifying factor enzyme 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1580.10 Alpha Beta Alpha-Beta Complex paralog of FGE (formylglycine-generating enzyme) paralog of FGE (formylglycine-generating enzyme) 1y1eX00
2AIKX 1Y1EX 1Z70X 2AFYX 1Y1IX 1YU0A 1Y1HX 1YU2A 1Y4JA 1YU4A 1YU1A 2AFTX 2AIJX 1Y1JX 1YU3A 2HIBX 1Y1GX 2Y3CA 2HI8X 2Q17A 2IOUA 2AIIX 1Y1FX
chains in the Genus database with same CATH superfamily
2AIKX 1Y1EX 1Z70X 2AFYX 1Y1IX 1YU0A 1Y1HX 1YU2A 1Y4JA 1YU4A 1YU1A 2AFTX 2AIJX 1Y1JX 1YU3A 2HIBX 1Y1GX 2Y3CA 2HI8X 2Q17A 2IOUA 2AIIX 1Y1FX
chains in the Genus database with same CATH topology
2AIKX 1Y1EX 1Z70X 2AFYX 1Y1IX 1YU0A 1Y1HX 1YU2A 1Y4JA 1YU4A 1YU1A 2AFTX 2AIJX 1Y1JX 1YU3A 2HIBX 1Y1GX 2Y3CA 2HI8X 2Q17A 2IOUA 2AIIX 1Y1FX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AIK X;  1Y1E X;  1Z70 X;  2AFY X;  1Y1I X;  1YU0 A;  1Y1H X;  1YU2 A;  1Y4J A;  1YU4 A;  1YU1 A;  2AFT X;  2AIJ X;  1Y1J X;  1YU3 A;  2HIB X;  1Y1G X;  2Y3C A;  2HI8 X;  2Q17 A;  2IOU A;  2AII X;  1Y1F X; 
#chains in the Genus database with same CATH topology
 2AIK X;  1Y1E X;  1Z70 X;  2AFY X;  1Y1I X;  1YU0 A;  1Y1H X;  1YU2 A;  1Y4J A;  1YU4 A;  1YU1 A;  2AFT X;  2AIJ X;  1Y1J X;  1YU3 A;  2HIB X;  1Y1G X;  2Y3C A;  2HI8 X;  2Q17 A;  2IOU A;  2AII X;  1Y1F X; 
#chains in the Genus database with same CATH homology
 2AIK X;  1Y1E X;  1Z70 X;  2AFY X;  1Y1I X;  1YU0 A;  1Y1H X;  1YU2 A;  1Y4J A;  1YU4 A;  1YU1 A;  2AFT X;  2AIJ X;  1Y1J X;  1YU3 A;  2HIB X;  1Y1G X;  2Y3C A;  2HI8 X;  2Q17 A;  2IOU A;  2AII X;  1Y1F X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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