1Y1FX

Human formylglycine generating enzyme with cysteine sulfenic acid
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
286
structure length
271
Chain Sequence
LAHSKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTIDAFYMDAYEVSNTEFEKFVNSTGYLTEAEKFGDSFVFEGMLAPWWLPVKGANWRHPEGPDSTILHRPDHPVLHVSWNDAVAYCTWAGKRLPTEAEWEYSCRGGLHNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSVEETLNPKGPPSGKDRVKKGGSYMHRSYCYRYRCAARSQNTPDSSASNLGFRCAADRLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords C-alpha-formyglycine-generating enzyme
publication title Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme.
pubmed doi rcsb
source organism Homo sapiens
total genus 79
structure length 271
sequence length 286
ec nomenclature ec 1.8.3.7: Formylglycine-generating enzyme.
pdb deposition date 2004-11-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1580.10 Alpha Beta Alpha-Beta Complex paralog of FGE (formylglycine-generating enzyme) paralog of FGE (formylglycine-generating enzyme) 1y1fX00
2Y3CA 1YU2A 1Y1HX 1Z70X 1YU1A 2Q17A 2AIKX 1Y1IX 2AIIX 1Y1JX 1Y1GX 2HIBX 1YU4A 2AFTX 2AIJX 2HI8X 1Y4JA 2IOUA 1YU3A 1Y1EX 1Y1FX 2AFYX 1YU0A
chains in the Genus database with same CATH superfamily
2Y3CA 1YU2A 1Y1HX 1Z70X 1YU1A 2Q17A 2AIKX 1Y1IX 2AIIX 1Y1JX 1Y1GX 2HIBX 1YU4A 2AFTX 2AIJX 2HI8X 1Y4JA 2IOUA 1YU3A 1Y1EX 1Y1FX 2AFYX 1YU0A
chains in the Genus database with same CATH topology
2Y3CA 1YU2A 1Y1HX 1Z70X 1YU1A 2Q17A 2AIKX 1Y1IX 2AIIX 1Y1JX 1Y1GX 2HIBX 1YU4A 2AFTX 2AIJX 2HI8X 1Y4JA 2IOUA 1YU3A 1Y1EX 1Y1FX 2AFYX 1YU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y3C A;  1YU2 A;  1Y1H X;  1Z70 X;  1YU1 A;  2Q17 A;  2AIK X;  1Y1I X;  2AII X;  1Y1J X;  1Y1G X;  2HIB X;  1YU4 A;  2AFT X;  2AIJ X;  2HI8 X;  1Y4J A;  2IOU A;  1YU3 A;  1Y1E X;  1Y1F X;  2AFY X;  1YU0 A; 
#chains in the Genus database with same CATH topology
 2Y3C A;  1YU2 A;  1Y1H X;  1Z70 X;  1YU1 A;  2Q17 A;  2AIK X;  1Y1I X;  2AII X;  1Y1J X;  1Y1G X;  2HIB X;  1YU4 A;  2AFT X;  2AIJ X;  2HI8 X;  1Y4J A;  2IOU A;  1YU3 A;  1Y1E X;  1Y1F X;  2AFY X;  1YU0 A; 
#chains in the Genus database with same CATH homology
 2Y3C A;  1YU2 A;  1Y1H X;  1Z70 X;  1YU1 A;  2Q17 A;  2AIK X;  1Y1I X;  2AII X;  1Y1J X;  1Y1G X;  2HIB X;  1YU4 A;  2AFT X;  2AIJ X;  2HI8 X;  1Y4J A;  2IOU A;  1YU3 A;  1Y1E X;  1Y1F X;  2AFY X;  1YU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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