1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase 1B
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
1BOAA 1WKMA 2P9AA 4IDYA 4U69A 4U6WA 4ZWPA 2BWXA 4RZZA 1R5GA 1C21A 4FLKA 4U6EA 2V6CA 3MATA 4IPAA 5CDLA 4OOKA 2ADUA 2OKNA 2GU6A 1WY2A 1MATA 1B6AA 3IU8A 4PV4A 1CHMA 5FCHA 3D27A 3IG4A 3S6BA 4IF7A 1XGOA 1YW7A 4B28A 3L24A 3RVAA 1O0XA 4S01A 4FKCA 4EGEA 1WBQA 3FM3A 1XGSA 1R5HA 3MX6A 2HOWA 3CB5A 2BWSA 5D6EA 2P98A 2G6PA 3PKAA 2EVOA 5JHUA 1QXWA 3BIPA 1WN1A 5CDEA 3BIQA 5JFRA 4A6WA 4A6VA 1QXZA 1WLRA 3CTZA 4R60A 1Y1NA 2B3KA 2Q8KA 4FLJA 4PNCA 2Q96A 1C24A 4FO8A 4U75A 3IU7A 3Q6DA 2Q94A 3PKDA 2GG5A 1YJ3A 2MATA 4U6JA 1N51A 3MR1A 1W2MA 2GZ5A 2V3ZA 2GG3A 2BWUA 2GG7A 4QR8A 4KM3A 1YW8A 4FLIA 4IKSA 5CLSA 2BB7A 3PKEA 1XGNA 4ZWUA 4IECA 3TB5A 1C23A 2B3HA 2EVMA 1PV9A 1QZYA 2GG0A 1XNZA 1JAWA 5D6FA 1C22A 1YVMA 4RGZ1 3FMQA 1M35A 1KQ9A 1WL9A 3FMRA 2GA2A 3TAVA 4U76A 2GU5A 5E5BA 1A16A 4IKUA 5FCFA 5CE6A 1YW9A 5CDVA 1BN5A 2GG9A 3RORA 5JI6A 4RZYA 3IU9A 3L7GA 4U1BA 2BHDA 1B59A 2NQ7A 4IU6A 4MATA 2V3YA 2BHBA 2Q95A 4FUKA 4U71A 2Q92A 1KP0A 5CNXA 2EA4A 1R58A 4FO7A 2BWYA 1C27A 2BH3A 4HXXA 4IKRA 4Z7MA 1WL6A 2GGBA 2EVCA 2BN7A 2BHAA 2GU7A 2DFIA 2OAZA 4U70A 4U6ZA 2EA2A 4U73A 2BWVA 4JUQA 2GU4A 5CIKA 1XGMA 2ZSGA 1QXYA 4IKTA 2GG2A 3PKCA 4ZNGA 2IW2A 4S2TP 2NQ6A 4S00A 2GGCA 4ZWOA 4S2RP 3CB6A 1W7VA 1KQ0A 2P99A 2Q93A 2B3LA 4FLLA 2BWTA 3PKBA 2GTXA 4U6CA 2BHCA 2BWWA 2V3XA 2GG8A 3BITA
chains in the Genus database with same CATH superfamily
1BOAA 1WKMA 2P9AA 4IDYA 4U69A 4U6WA 4ZWPA 2BWXA 4RZZA 1R5GA 1C21A 4FLKA 4U6EA 2V6CA 3MATA 4IPAA 5CDLA 4OOKA 2ADUA 2OKNA 2GU6A 1WY2A 1MATA 1B6AA 3IU8A 4PV4A 1CHMA 5FCHA 3D27A 3IG4A 3S6BA 4IF7A 1XGOA 1YW7A 4B28A 3L24A 3RVAA 1O0XA 4S01A 4FKCA 4EGEA 1WBQA 3FM3A 1XGSA 1R5HA 3MX6A 2HOWA 3CB5A 2BWSA 5D6EA 2P98A 2G6PA 3PKAA 2EVOA 5JHUA 1QXWA 3BIPA 1WN1A 5CDEA 3BIQA 5JFRA 4A6WA 4A6VA 1QXZA 1WLRA 3CTZA 4R60A 1Y1NA 2B3KA 2Q8KA 4FLJA 4PNCA 2Q96A 1C24A 4FO8A 4U75A 3IU7A 3Q6DA 2Q94A 3PKDA 2GG5A 1YJ3A 2MATA 4U6JA 1N51A 3MR1A 1W2MA 2GZ5A 2V3ZA 2GG3A 2BWUA 2GG7A 4QR8A 4KM3A 1YW8A 4FLIA 4IKSA 5CLSA 2BB7A 3PKEA 1XGNA 4ZWUA 4IECA 3TB5A 1C23A 2B3HA 2EVMA 1PV9A 1QZYA 2GG0A 1XNZA 1JAWA 5D6FA 1C22A 1YVMA 4RGZ1 3FMQA 1M35A 1KQ9A 1WL9A 3FMRA 2GA2A 3TAVA 4U76A 2GU5A 5E5BA 1A16A 4IKUA 5FCFA 5CE6A 1YW9A 5CDVA 1BN5A 2GG9A 3RORA 5JI6A 4RZYA 3IU9A 3L7GA 4U1BA 2BHDA 1B59A 2NQ7A 4IU6A 4MATA 2V3YA 2BHBA 2Q95A 4FUKA 4U71A 2Q92A 1KP0A 5CNXA 2EA4A 1R58A 4FO7A 2BWYA 1C27A 2BH3A 4HXXA 4IKRA 4Z7MA 1WL6A 2GGBA 2EVCA 2BN7A 2BHAA 2GU7A 2DFIA 2OAZA 4U70A 4U6ZA 2EA2A 4U73A 2BWVA 4JUQA 2GU4A 5CIKA 1XGMA 2ZSGA 1QXYA 4IKTA 2GG2A 3PKCA 4ZNGA 2IW2A 4S2TP 2NQ6A 4S00A 2GGCA 4ZWOA 4S2RP 3CB6A 1W7VA 1KQ0A 2P99A 2Q93A 2B3LA 4FLLA 2BWTA 3PKBA 2GTXA 4U6CA 2BHCA 2BWWA 2V3XA 2GG8A 3BITA
chains in the Genus database with same CATH topology
1BOAA 1WKMA 2P9AA 4IDYA 4U69A 4U6WA 4ZWPA 2BWXA 4RZZA 1R5GA 1C21A 4FLKA 4U6EA 2V6CA 3MATA 4IPAA 5CDLA 4OOKA 2ADUA 2OKNA 2GU6A 1WY2A 1MATA 1B6AA 3IU8A 4PV4A 1CHMA 5FCHA 3D27A 3IG4A 3S6BA 4IF7A 1XGOA 1YW7A 4B28A 3L24A 3RVAA 1O0XA 4S01A 4FKCA 4EGEA 1WBQA 3FM3A 1XGSA 1R5HA 3MX6A 2HOWA 3CB5A 2BWSA 5D6EA 2P98A 2G6PA 3PKAA 2EVOA 5JHUA 1QXWA 3BIPA 1WN1A 5CDEA 3BIQA 5JFRA 4A6WA 4A6VA 1QXZA 1WLRA 3CTZA 4R60A 1Y1NA 2B3KA 2Q8KA 4FLJA 4PNCA 2Q96A 1C24A 4FO8A 4U75A 3IU7A 3Q6DA 2Q94A 3PKDA 2GG5A 1YJ3A 2MATA 4U6JA 1N51A 3MR1A 1W2MA 2GZ5A 2V3ZA 2GG3A 2BWUA 2GG7A 4QR8A 4KM3A 1YW8A 4FLIA 4IKSA 5CLSA 2BB7A 3PKEA 1XGNA 4ZWUA 4IECA 3TB5A 1C23A 2B3HA 2EVMA 1PV9A 1QZYA 2GG0A 1XNZA 1JAWA 5D6FA 1C22A 1YVMA 4RGZ1 3FMQA 1M35A 1KQ9A 1WL9A 3FMRA 2GA2A 3TAVA 4U76A 2GU5A 5E5BA 1A16A 4IKUA 5FCFA 5CE6A 1YW9A 5CDVA 1BN5A 2GG9A 3RORA 5JI6A 4RZYA 3IU9A 3L7GA 4U1BA 2BHDA 1B59A 2NQ7A 4IU6A 4MATA 2V3YA 2BHBA 2Q95A 4FUKA 4U71A 2Q92A 1KP0A 5CNXA 2EA4A 1R58A 4FO7A 2BWYA 1C27A 2BH3A 4HXXA 4IKRA 4Z7MA 1WL6A 2GGBA 2EVCA 2BN7A 2BHAA 2GU7A 2DFIA 2OAZA 4U70A 4U6ZA 2EA2A 4U73A 2BWVA 4JUQA 2GU4A 5CIKA 1XGMA 2ZSGA 1QXYA 4IKTA 2GG2A 3PKCA 4ZNGA 2IW2A 4S2TP 2NQ6A 4S00A 2GGCA 4ZWOA 4S2RP 3CB6A 1W7VA 1KQ0A 2P99A 2Q93A 2B3LA 4FLLA 2BWTA 3PKBA 2GTXA 4U6CA 2BHCA 2BWWA 2V3XA 2GG8A 3BITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BOA A;  1WKM A;  2P9A A;  4IDY A;  4U69 A;  4U6W A;  4ZWP A;  2BWX A;  4RZZ A;  1R5G A;  1C21 A;  4FLK A;  4U6E A;  2V6C A;  3MAT A;  4IPA A;  5CDL A;  4OOK A;  2ADU A;  2OKN A;  2GU6 A;  1WY2 A;  1MAT A;  1B6A A;  3IU8 A;  4PV4 A;  1CHM A;  5FCH A;  3D27 A;  3IG4 A;  3S6B A;  4IF7 A;  1XGO A;  1YW7 A;  4B28 A;  3L24 A;  3RVA A;  1O0X A;  4S01 A;  4FKC A;  4EGE A;  1WBQ A;  3FM3 A;  1XGS A;  1R5H A;  3MX6 A;  2HOW A;  3CB5 A;  2BWS A;  5D6E A;  2P98 A;  2G6P A;  3PKA A;  2EVO A;  5JHU A;  1QXW A;  3BIP A;  1WN1 A;  5CDE A;  3BIQ A;  5JFR A;  4A6W A;  4A6V A;  1QXZ A;  1WLR A;  3CTZ A;  4R60 A;  1Y1N A;  2B3K A;  2Q8K A;  4FLJ A;  4PNC A;  2Q96 A;  1C24 A;  4FO8 A;  4U75 A;  3IU7 A;  3Q6D A;  2Q94 A;  3PKD A;  2GG5 A;  1YJ3 A;  2MAT A;  4U6J A;  1N51 A;  3MR1 A;  1W2M A;  2GZ5 A;  2V3Z A;  2GG3 A;  2BWU A;  2GG7 A;  4QR8 A;  4KM3 A;  1YW8 A;  4FLI A;  4IKS A;  5CLS A;  2BB7 A;  3PKE A;  1XGN A;  4ZWU A;  4IEC A;  3TB5 A;  1C23 A;  2B3H A;  2EVM A;  1PV9 A;  1QZY A;  2GG0 A;  1XNZ A;  1JAW A;  5D6F A;  1C22 A;  1YVM A;  4RGZ 1;  3FMQ A;  1M35 A;  1KQ9 A;  1WL9 A;  3FMR A;  2GA2 A;  3TAV A;  4U76 A;  2GU5 A;  5E5B A;  1A16 A;  4IKU A;  5FCF A;  5CE6 A;  1YW9 A;  5CDV A;  1BN5 A;  2GG9 A;  3ROR A;  5JI6 A;  4RZY A;  3IU9 A;  3L7G A;  4U1B A;  2BHD A;  1B59 A;  2NQ7 A;  4IU6 A;  4MAT A;  2V3Y A;  2BHB A;  2Q95 A;  4FUK A;  4U71 A;  2Q92 A;  1KP0 A;  5CNX A;  2EA4 A;  1R58 A;  4FO7 A;  2BWY A;  1C27 A;  2BH3 A;  4HXX A;  4IKR A;  4Z7M A;  1WL6 A;  2GGB A;  2EVC A;  2BN7 A;  2BHA A;  2GU7 A;  2DFI A;  2OAZ A;  4U70 A;  4U6Z A;  2EA2 A;  4U73 A;  2BWV A;  4JUQ A;  2GU4 A;  5CIK A;  1XGM A;  2ZSG A;  1QXY A;  4IKT A;  2GG2 A;  3PKC A;  4ZNG A;  2IW2 A;  4S2T P;  2NQ6 A;  4S00 A;  2GGC A;  4ZWO A;  4S2R P;  3CB6 A;  1W7V A;  1KQ0 A;  2P99 A;  2Q93 A;  2B3L A;  4FLL A;  2BWT A;  3PKB A;  2GTX A;  4U6C A;  2BHC A;  2BWW A;  2V3X A;  2GG8 A;  3BIT A; 
#chains in the Genus database with same CATH topology
 1BOA A;  1WKM A;  2P9A A;  4IDY A;  4U69 A;  4U6W A;  4ZWP A;  2BWX A;  4RZZ A;  1R5G A;  1C21 A;  4FLK A;  4U6E A;  2V6C A;  3MAT A;  4IPA A;  5CDL A;  4OOK A;  2ADU A;  2OKN A;  2GU6 A;  1WY2 A;  1MAT A;  1B6A A;  3IU8 A;  4PV4 A;  1CHM A;  5FCH A;  3D27 A;  3IG4 A;  3S6B A;  4IF7 A;  1XGO A;  1YW7 A;  4B28 A;  3L24 A;  3RVA A;  1O0X A;  4S01 A;  4FKC A;  4EGE A;  1WBQ A;  3FM3 A;  1XGS A;  1R5H A;  3MX6 A;  2HOW A;  3CB5 A;  2BWS A;  5D6E A;  2P98 A;  2G6P A;  3PKA A;  2EVO A;  5JHU A;  1QXW A;  3BIP A;  1WN1 A;  5CDE A;  3BIQ A;  5JFR A;  4A6W A;  4A6V A;  1QXZ A;  1WLR A;  3CTZ A;  4R60 A;  1Y1N A;  2B3K A;  2Q8K A;  4FLJ A;  4PNC A;  2Q96 A;  1C24 A;  4FO8 A;  4U75 A;  3IU7 A;  3Q6D A;  2Q94 A;  3PKD A;  2GG5 A;  1YJ3 A;  2MAT A;  4U6J A;  1N51 A;  3MR1 A;  1W2M A;  2GZ5 A;  2V3Z A;  2GG3 A;  2BWU A;  2GG7 A;  4QR8 A;  4KM3 A;  1YW8 A;  4FLI A;  4IKS A;  5CLS A;  2BB7 A;  3PKE A;  1XGN A;  4ZWU A;  4IEC A;  3TB5 A;  1C23 A;  2B3H A;  2EVM A;  1PV9 A;  1QZY A;  2GG0 A;  1XNZ A;  1JAW A;  5D6F A;  1C22 A;  1YVM A;  4RGZ 1;  3FMQ A;  1M35 A;  1KQ9 A;  1WL9 A;  3FMR A;  2GA2 A;  3TAV A;  4U76 A;  2GU5 A;  5E5B A;  1A16 A;  4IKU A;  5FCF A;  5CE6 A;  1YW9 A;  5CDV A;  1BN5 A;  2GG9 A;  3ROR A;  5JI6 A;  4RZY A;  3IU9 A;  3L7G A;  4U1B A;  2BHD A;  1B59 A;  2NQ7 A;  4IU6 A;  4MAT A;  2V3Y A;  2BHB A;  2Q95 A;  4FUK A;  4U71 A;  2Q92 A;  1KP0 A;  5CNX A;  2EA4 A;  1R58 A;  4FO7 A;  2BWY A;  1C27 A;  2BH3 A;  4HXX A;  4IKR A;  4Z7M A;  1WL6 A;  2GGB A;  2EVC A;  2BN7 A;  2BHA A;  2GU7 A;  2DFI A;  2OAZ A;  4U70 A;  4U6Z A;  2EA2 A;  4U73 A;  2BWV A;  4JUQ A;  2GU4 A;  5CIK A;  1XGM A;  2ZSG A;  1QXY A;  4IKT A;  2GG2 A;  3PKC A;  4ZNG A;  2IW2 A;  4S2T P;  2NQ6 A;  4S00 A;  2GGC A;  4ZWO A;  4S2R P;  3CB6 A;  1W7V A;  1KQ0 A;  2P99 A;  2Q93 A;  2B3L A;  4FLL A;  2BWT A;  3PKB A;  2GTX A;  4U6C A;  2BHC A;  2BWW A;  2V3X A;  2GG8 A;  3BIT A; 
#chains in the Genus database with same CATH homology
 1BOA A;  1WKM A;  2P9A A;  4IDY A;  4U69 A;  4U6W A;  4ZWP A;  2BWX A;  4RZZ A;  1R5G A;  1C21 A;  4FLK A;  4U6E A;  2V6C A;  3MAT A;  4IPA A;  5CDL A;  4OOK A;  2ADU A;  2OKN A;  2GU6 A;  1WY2 A;  1MAT A;  1B6A A;  3IU8 A;  4PV4 A;  1CHM A;  5FCH A;  3D27 A;  3IG4 A;  3S6B A;  4IF7 A;  1XGO A;  1YW7 A;  4B28 A;  3L24 A;  3RVA A;  1O0X A;  4S01 A;  4FKC A;  4EGE A;  1WBQ A;  3FM3 A;  1XGS A;  1R5H A;  3MX6 A;  2HOW A;  3CB5 A;  2BWS A;  5D6E A;  2P98 A;  2G6P A;  3PKA A;  2EVO A;  5JHU A;  1QXW A;  3BIP A;  1WN1 A;  5CDE A;  3BIQ A;  5JFR A;  4A6W A;  4A6V A;  1QXZ A;  1WLR A;  3CTZ A;  4R60 A;  1Y1N A;  2B3K A;  2Q8K A;  4FLJ A;  4PNC A;  2Q96 A;  1C24 A;  4FO8 A;  4U75 A;  3IU7 A;  3Q6D A;  2Q94 A;  3PKD A;  2GG5 A;  1YJ3 A;  2MAT A;  4U6J A;  1N51 A;  3MR1 A;  1W2M A;  2GZ5 A;  2V3Z A;  2GG3 A;  2BWU A;  2GG7 A;  4QR8 A;  4KM3 A;  1YW8 A;  4FLI A;  4IKS A;  5CLS A;  2BB7 A;  3PKE A;  1XGN A;  4ZWU A;  4IEC A;  3TB5 A;  1C23 A;  2B3H A;  2EVM A;  1PV9 A;  1QZY A;  2GG0 A;  1XNZ A;  1JAW A;  5D6F A;  1C22 A;  1YVM A;  4RGZ 1;  3FMQ A;  1M35 A;  1KQ9 A;  1WL9 A;  3FMR A;  2GA2 A;  3TAV A;  4U76 A;  2GU5 A;  5E5B A;  1A16 A;  4IKU A;  5FCF A;  5CE6 A;  1YW9 A;  5CDV A;  1BN5 A;  2GG9 A;  3ROR A;  5JI6 A;  4RZY A;  3IU9 A;  3L7G A;  4U1B A;  2BHD A;  1B59 A;  2NQ7 A;  4IU6 A;  4MAT A;  2V3Y A;  2BHB A;  2Q95 A;  4FUK A;  4U71 A;  2Q92 A;  1KP0 A;  5CNX A;  2EA4 A;  1R58 A;  4FO7 A;  2BWY A;  1C27 A;  2BH3 A;  4HXX A;  4IKR A;  4Z7M A;  1WL6 A;  2GGB A;  2EVC A;  2BN7 A;  2BHA A;  2GU7 A;  2DFI A;  2OAZ A;  4U70 A;  4U6Z A;  2EA2 A;  4U73 A;  2BWV A;  4JUQ A;  2GU4 A;  5CIK A;  1XGM A;  2ZSG A;  1QXY A;  4IKT A;  2GG2 A;  3PKC A;  4ZNG A;  2IW2 A;  4S2T P;  2NQ6 A;  4S00 A;  2GGC A;  4ZWO A;  4S2R P;  3CB6 A;  1W7V A;  1KQ0 A;  2P99 A;  2Q93 A;  2B3L A;  4FLL A;  2BWT A;  3PKB A;  2GTX A;  4U6C A;  2BHC A;  2BWW A;  2V3X A;  2GG8 A;  3BIT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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