1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase 1B
publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
3IU8A 1BN5A 4JUQA 4Z7MA 4IKUA 1WY2A 3PKBA 4MATA 4IECA 1MATA 4U6CA 4U76A 2GG8A 5CLSA 4S00A 3BITA 1WBQA 2GG2A 4IKSA 2BB7A 2BWYA 2OKNA 1O0XA 2EVCA 2EVMA 2V3XA 4ZWOA 3TAVA 2BWTA 5CNXA 2V6CA 5CIKA 1Y1NA 1C27A 2NQ7A 5D6FA 2GG0A 1C23A 2GG3A 4IF7A 4S01A 2GG9A 1QXYA 2BWVA 2BHCA 4RZYA 1WLRA 3MX6A 2BHDA 1KQ0A 1YW8A 4U6EA 4U6JA 1WL6A 2BN7A 5JI6A 1N51A 1YW7A 4U6WA 4U6ZA 1C22A 3TB5A 3PKCA 1XNZA 2Q95A 2Q96A 3MR1A 4IKTA 2DFIA 3FM3A 4IKRA 1A16A 1R58A 4IPAA 4U70A 3PKAA 4IU6A 3RORA 5CDLA 4KM3A 2B3HA 2P9AA 4S2RP 1XGNA 1B6AA 2EVOA 4OOKA 4ZNGA 2GZ5A 5FCFA 2B3LA 5FCHA 2GTXA 1WKMA 4B28A 1JAWA 1YW9A 1QXWA 1W7VA 1QXZA 4FO7A 4FO8A 2EA2A 2P98A 4FUKA 3PKEA 1WN1A 3S6BA 4PV4A 1XGOA 4U1BA 4U75A 2GG5A 2BWWA 2GG7A 3CB6A 4A6WA 3FMQA 1R5GA 1BOAA 2EA4A 1XGSA 2B3KA 4HXXA 4IDYA 2Q8KA 3CTZA 1CHMA 4RGZ1 3PKDA 4EGEA 2Q92A 3Q6DA 1R5HA 1YVMA 2ZSGA 2MATA 5E5BA 2ADUA 5CDEA 2BWXA 2GGBA 4U73A 3BIQA 2BHAA 4QR8A 4ZWUA 3RVAA 2GU5A 4FLJA 4A6VA 5CDVA 2HOWA 2GU6A 2P99A 4RZZA 4S2TP 1KQ9A 2OAZA 4PNCA 1C24A 2BHBA 5JHUA 1YJ3A 4ZWPA 4U71A 3MATA 1XGMA 1C21A 1W2MA 2BH3A 3L7GA 4FLIA 2IW2A 3IU7A 1B59A 2V3YA 1QZYA 2NQ6A 2G6PA 2GGCA 2Q93A 2GU4A 4FLLA 3L24A 1WL9A 5D6EA 1M35A 2BWSA 4FLKA 4U69A 5JFRA 5CE6A 3BIPA 3FMRA 3D27A 2Q94A 2BWUA 2V3ZA 3CB5A 2GA2A 1KP0A 2GU7A 4R60A 4FKCA 3IG4A 1PV9A 3IU9A
chains in the Genus database with same CATH superfamily
3IU8A 1BN5A 4JUQA 4Z7MA 4IKUA 1WY2A 3PKBA 4MATA 4IECA 1MATA 4U6CA 4U76A 2GG8A 5CLSA 4S00A 3BITA 1WBQA 2GG2A 4IKSA 2BB7A 2BWYA 2OKNA 1O0XA 2EVCA 2EVMA 2V3XA 4ZWOA 3TAVA 2BWTA 5CNXA 2V6CA 5CIKA 1Y1NA 1C27A 2NQ7A 5D6FA 2GG0A 1C23A 2GG3A 4IF7A 4S01A 2GG9A 1QXYA 2BWVA 2BHCA 4RZYA 1WLRA 3MX6A 2BHDA 1KQ0A 1YW8A 4U6EA 4U6JA 1WL6A 2BN7A 5JI6A 1N51A 1YW7A 4U6WA 4U6ZA 1C22A 3TB5A 3PKCA 1XNZA 2Q95A 2Q96A 3MR1A 4IKTA 2DFIA 3FM3A 4IKRA 1A16A 1R58A 4IPAA 4U70A 3PKAA 4IU6A 3RORA 5CDLA 4KM3A 2B3HA 2P9AA 4S2RP 1XGNA 1B6AA 2EVOA 4OOKA 4ZNGA 2GZ5A 5FCFA 2B3LA 5FCHA 2GTXA 1WKMA 4B28A 1JAWA 1YW9A 1QXWA 1W7VA 1QXZA 4FO7A 4FO8A 2EA2A 2P98A 4FUKA 3PKEA 1WN1A 3S6BA 4PV4A 1XGOA 4U1BA 4U75A 2GG5A 2BWWA 2GG7A 3CB6A 4A6WA 3FMQA 1R5GA 1BOAA 2EA4A 1XGSA 2B3KA 4HXXA 4IDYA 2Q8KA 3CTZA 1CHMA 4RGZ1 3PKDA 4EGEA 2Q92A 3Q6DA 1R5HA 1YVMA 2ZSGA 2MATA 5E5BA 2ADUA 5CDEA 2BWXA 2GGBA 4U73A 3BIQA 2BHAA 4QR8A 4ZWUA 3RVAA 2GU5A 4FLJA 4A6VA 5CDVA 2HOWA 2GU6A 2P99A 4RZZA 4S2TP 1KQ9A 2OAZA 4PNCA 1C24A 2BHBA 5JHUA 1YJ3A 4ZWPA 4U71A 3MATA 1XGMA 1C21A 1W2MA 2BH3A 3L7GA 4FLIA 2IW2A 3IU7A 1B59A 2V3YA 1QZYA 2NQ6A 2G6PA 2GGCA 2Q93A 2GU4A 4FLLA 3L24A 1WL9A 5D6EA 1M35A 2BWSA 4FLKA 4U69A 5JFRA 5CE6A 3BIPA 3FMRA 3D27A 2Q94A 2BWUA 2V3ZA 3CB5A 2GA2A 1KP0A 2GU7A 4R60A 4FKCA 3IG4A 1PV9A 3IU9A
chains in the Genus database with same CATH topology
3IU8A 1BN5A 4JUQA 4Z7MA 4IKUA 1WY2A 3PKBA 4MATA 4IECA 1MATA 4U6CA 4U76A 2GG8A 5CLSA 4S00A 3BITA 1WBQA 2GG2A 4IKSA 2BB7A 2BWYA 2OKNA 1O0XA 2EVCA 2EVMA 2V3XA 4ZWOA 3TAVA 2BWTA 5CNXA 2V6CA 5CIKA 1Y1NA 1C27A 2NQ7A 5D6FA 2GG0A 1C23A 2GG3A 4IF7A 4S01A 2GG9A 1QXYA 2BWVA 2BHCA 4RZYA 1WLRA 3MX6A 2BHDA 1KQ0A 1YW8A 4U6EA 4U6JA 1WL6A 2BN7A 5JI6A 1N51A 1YW7A 4U6WA 4U6ZA 1C22A 3TB5A 3PKCA 1XNZA 2Q95A 2Q96A 3MR1A 4IKTA 2DFIA 3FM3A 4IKRA 1A16A 1R58A 4IPAA 4U70A 3PKAA 4IU6A 3RORA 5CDLA 4KM3A 2B3HA 2P9AA 4S2RP 1XGNA 1B6AA 2EVOA 4OOKA 4ZNGA 2GZ5A 5FCFA 2B3LA 5FCHA 2GTXA 1WKMA 4B28A 1JAWA 1YW9A 1QXWA 1W7VA 1QXZA 4FO7A 4FO8A 2EA2A 2P98A 4FUKA 3PKEA 1WN1A 3S6BA 4PV4A 1XGOA 4U1BA 4U75A 2GG5A 2BWWA 2GG7A 3CB6A 4A6WA 3FMQA 1R5GA 1BOAA 2EA4A 1XGSA 2B3KA 4HXXA 4IDYA 2Q8KA 3CTZA 1CHMA 4RGZ1 3PKDA 4EGEA 2Q92A 3Q6DA 1R5HA 1YVMA 2ZSGA 2MATA 5E5BA 2ADUA 5CDEA 2BWXA 2GGBA 4U73A 3BIQA 2BHAA 4QR8A 4ZWUA 3RVAA 2GU5A 4FLJA 4A6VA 5CDVA 2HOWA 2GU6A 2P99A 4RZZA 4S2TP 1KQ9A 2OAZA 4PNCA 1C24A 2BHBA 5JHUA 1YJ3A 4ZWPA 4U71A 3MATA 1XGMA 1C21A 1W2MA 2BH3A 3L7GA 4FLIA 2IW2A 3IU7A 1B59A 2V3YA 1QZYA 2NQ6A 2G6PA 2GGCA 2Q93A 2GU4A 4FLLA 3L24A 1WL9A 5D6EA 1M35A 2BWSA 4FLKA 4U69A 5JFRA 5CE6A 3BIPA 3FMRA 3D27A 2Q94A 2BWUA 2V3ZA 3CB5A 2GA2A 1KP0A 2GU7A 4R60A 4FKCA 3IG4A 1PV9A 3IU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IU8 A;  1BN5 A;  4JUQ A;  4Z7M A;  4IKU A;  1WY2 A;  3PKB A;  4MAT A;  4IEC A;  1MAT A;  4U6C A;  4U76 A;  2GG8 A;  5CLS A;  4S00 A;  3BIT A;  1WBQ A;  2GG2 A;  4IKS A;  2BB7 A;  2BWY A;  2OKN A;  1O0X A;  2EVC A;  2EVM A;  2V3X A;  4ZWO A;  3TAV A;  2BWT A;  5CNX A;  2V6C A;  5CIK A;  1Y1N A;  1C27 A;  2NQ7 A;  5D6F A;  2GG0 A;  1C23 A;  2GG3 A;  4IF7 A;  4S01 A;  2GG9 A;  1QXY A;  2BWV A;  2BHC A;  4RZY A;  1WLR A;  3MX6 A;  2BHD A;  1KQ0 A;  1YW8 A;  4U6E A;  4U6J A;  1WL6 A;  2BN7 A;  5JI6 A;  1N51 A;  1YW7 A;  4U6W A;  4U6Z A;  1C22 A;  3TB5 A;  3PKC A;  1XNZ A;  2Q95 A;  2Q96 A;  3MR1 A;  4IKT A;  2DFI A;  3FM3 A;  4IKR A;  1A16 A;  1R58 A;  4IPA A;  4U70 A;  3PKA A;  4IU6 A;  3ROR A;  5CDL A;  4KM3 A;  2B3H A;  2P9A A;  4S2R P;  1XGN A;  1B6A A;  2EVO A;  4OOK A;  4ZNG A;  2GZ5 A;  5FCF A;  2B3L A;  5FCH A;  2GTX A;  1WKM A;  4B28 A;  1JAW A;  1YW9 A;  1QXW A;  1W7V A;  1QXZ A;  4FO7 A;  4FO8 A;  2EA2 A;  2P98 A;  4FUK A;  3PKE A;  1WN1 A;  3S6B A;  4PV4 A;  1XGO A;  4U1B A;  4U75 A;  2GG5 A;  2BWW A;  2GG7 A;  3CB6 A;  4A6W A;  3FMQ A;  1R5G A;  1BOA A;  2EA4 A;  1XGS A;  2B3K A;  4HXX A;  4IDY A;  2Q8K A;  3CTZ A;  1CHM A;  4RGZ 1;  3PKD A;  4EGE A;  2Q92 A;  3Q6D A;  1R5H A;  1YVM A;  2ZSG A;  2MAT A;  5E5B A;  2ADU A;  5CDE A;  2BWX A;  2GGB A;  4U73 A;  3BIQ A;  2BHA A;  4QR8 A;  4ZWU A;  3RVA A;  2GU5 A;  4FLJ A;  4A6V A;  5CDV A;  2HOW A;  2GU6 A;  2P99 A;  4RZZ A;  4S2T P;  1KQ9 A;  2OAZ A;  4PNC A;  1C24 A;  2BHB A;  5JHU A;  1YJ3 A;  4ZWP A;  4U71 A;  3MAT A;  1XGM A;  1C21 A;  1W2M A;  2BH3 A;  3L7G A;  4FLI A;  2IW2 A;  3IU7 A;  1B59 A;  2V3Y A;  1QZY A;  2NQ6 A;  2G6P A;  2GGC A;  2Q93 A;  2GU4 A;  4FLL A;  3L24 A;  1WL9 A;  5D6E A;  1M35 A;  2BWS A;  4FLK A;  4U69 A;  5JFR A;  5CE6 A;  3BIP A;  3FMR A;  3D27 A;  2Q94 A;  2BWU A;  2V3Z A;  3CB5 A;  2GA2 A;  1KP0 A;  2GU7 A;  4R60 A;  4FKC A;  3IG4 A;  1PV9 A;  3IU9 A; 
#chains in the Genus database with same CATH topology
 3IU8 A;  1BN5 A;  4JUQ A;  4Z7M A;  4IKU A;  1WY2 A;  3PKB A;  4MAT A;  4IEC A;  1MAT A;  4U6C A;  4U76 A;  2GG8 A;  5CLS A;  4S00 A;  3BIT A;  1WBQ A;  2GG2 A;  4IKS A;  2BB7 A;  2BWY A;  2OKN A;  1O0X A;  2EVC A;  2EVM A;  2V3X A;  4ZWO A;  3TAV A;  2BWT A;  5CNX A;  2V6C A;  5CIK A;  1Y1N A;  1C27 A;  2NQ7 A;  5D6F A;  2GG0 A;  1C23 A;  2GG3 A;  4IF7 A;  4S01 A;  2GG9 A;  1QXY A;  2BWV A;  2BHC A;  4RZY A;  1WLR A;  3MX6 A;  2BHD A;  1KQ0 A;  1YW8 A;  4U6E A;  4U6J A;  1WL6 A;  2BN7 A;  5JI6 A;  1N51 A;  1YW7 A;  4U6W A;  4U6Z A;  1C22 A;  3TB5 A;  3PKC A;  1XNZ A;  2Q95 A;  2Q96 A;  3MR1 A;  4IKT A;  2DFI A;  3FM3 A;  4IKR A;  1A16 A;  1R58 A;  4IPA A;  4U70 A;  3PKA A;  4IU6 A;  3ROR A;  5CDL A;  4KM3 A;  2B3H A;  2P9A A;  4S2R P;  1XGN A;  1B6A A;  2EVO A;  4OOK A;  4ZNG A;  2GZ5 A;  5FCF A;  2B3L A;  5FCH A;  2GTX A;  1WKM A;  4B28 A;  1JAW A;  1YW9 A;  1QXW A;  1W7V A;  1QXZ A;  4FO7 A;  4FO8 A;  2EA2 A;  2P98 A;  4FUK A;  3PKE A;  1WN1 A;  3S6B A;  4PV4 A;  1XGO A;  4U1B A;  4U75 A;  2GG5 A;  2BWW A;  2GG7 A;  3CB6 A;  4A6W A;  3FMQ A;  1R5G A;  1BOA A;  2EA4 A;  1XGS A;  2B3K A;  4HXX A;  4IDY A;  2Q8K A;  3CTZ A;  1CHM A;  4RGZ 1;  3PKD A;  4EGE A;  2Q92 A;  3Q6D A;  1R5H A;  1YVM A;  2ZSG A;  2MAT A;  5E5B A;  2ADU A;  5CDE A;  2BWX A;  2GGB A;  4U73 A;  3BIQ A;  2BHA A;  4QR8 A;  4ZWU A;  3RVA A;  2GU5 A;  4FLJ A;  4A6V A;  5CDV A;  2HOW A;  2GU6 A;  2P99 A;  4RZZ A;  4S2T P;  1KQ9 A;  2OAZ A;  4PNC A;  1C24 A;  2BHB A;  5JHU A;  1YJ3 A;  4ZWP A;  4U71 A;  3MAT A;  1XGM A;  1C21 A;  1W2M A;  2BH3 A;  3L7G A;  4FLI A;  2IW2 A;  3IU7 A;  1B59 A;  2V3Y A;  1QZY A;  2NQ6 A;  2G6P A;  2GGC A;  2Q93 A;  2GU4 A;  4FLL A;  3L24 A;  1WL9 A;  5D6E A;  1M35 A;  2BWS A;  4FLK A;  4U69 A;  5JFR A;  5CE6 A;  3BIP A;  3FMR A;  3D27 A;  2Q94 A;  2BWU A;  2V3Z A;  3CB5 A;  2GA2 A;  1KP0 A;  2GU7 A;  4R60 A;  4FKC A;  3IG4 A;  1PV9 A;  3IU9 A; 
#chains in the Genus database with same CATH homology
 3IU8 A;  1BN5 A;  4JUQ A;  4Z7M A;  4IKU A;  1WY2 A;  3PKB A;  4MAT A;  4IEC A;  1MAT A;  4U6C A;  4U76 A;  2GG8 A;  5CLS A;  4S00 A;  3BIT A;  1WBQ A;  2GG2 A;  4IKS A;  2BB7 A;  2BWY A;  2OKN A;  1O0X A;  2EVC A;  2EVM A;  2V3X A;  4ZWO A;  3TAV A;  2BWT A;  5CNX A;  2V6C A;  5CIK A;  1Y1N A;  1C27 A;  2NQ7 A;  5D6F A;  2GG0 A;  1C23 A;  2GG3 A;  4IF7 A;  4S01 A;  2GG9 A;  1QXY A;  2BWV A;  2BHC A;  4RZY A;  1WLR A;  3MX6 A;  2BHD A;  1KQ0 A;  1YW8 A;  4U6E A;  4U6J A;  1WL6 A;  2BN7 A;  5JI6 A;  1N51 A;  1YW7 A;  4U6W A;  4U6Z A;  1C22 A;  3TB5 A;  3PKC A;  1XNZ A;  2Q95 A;  2Q96 A;  3MR1 A;  4IKT A;  2DFI A;  3FM3 A;  4IKR A;  1A16 A;  1R58 A;  4IPA A;  4U70 A;  3PKA A;  4IU6 A;  3ROR A;  5CDL A;  4KM3 A;  2B3H A;  2P9A A;  4S2R P;  1XGN A;  1B6A A;  2EVO A;  4OOK A;  4ZNG A;  2GZ5 A;  5FCF A;  2B3L A;  5FCH A;  2GTX A;  1WKM A;  4B28 A;  1JAW A;  1YW9 A;  1QXW A;  1W7V A;  1QXZ A;  4FO7 A;  4FO8 A;  2EA2 A;  2P98 A;  4FUK A;  3PKE A;  1WN1 A;  3S6B A;  4PV4 A;  1XGO A;  4U1B A;  4U75 A;  2GG5 A;  2BWW A;  2GG7 A;  3CB6 A;  4A6W A;  3FMQ A;  1R5G A;  1BOA A;  2EA4 A;  1XGS A;  2B3K A;  4HXX A;  4IDY A;  2Q8K A;  3CTZ A;  1CHM A;  4RGZ 1;  3PKD A;  4EGE A;  2Q92 A;  3Q6D A;  1R5H A;  1YVM A;  2ZSG A;  2MAT A;  5E5B A;  2ADU A;  5CDE A;  2BWX A;  2GGB A;  4U73 A;  3BIQ A;  2BHA A;  4QR8 A;  4ZWU A;  3RVA A;  2GU5 A;  4FLJ A;  4A6V A;  5CDV A;  2HOW A;  2GU6 A;  2P99 A;  4RZZ A;  4S2T P;  1KQ9 A;  2OAZ A;  4PNC A;  1C24 A;  2BHB A;  5JHU A;  1YJ3 A;  4ZWP A;  4U71 A;  3MAT A;  1XGM A;  1C21 A;  1W2M A;  2BH3 A;  3L7G A;  4FLI A;  2IW2 A;  3IU7 A;  1B59 A;  2V3Y A;  1QZY A;  2NQ6 A;  2G6P A;  2GGC A;  2Q93 A;  2GU4 A;  4FLL A;  3L24 A;  1WL9 A;  5D6E A;  1M35 A;  2BWS A;  4FLK A;  4U69 A;  5JFR A;  5CE6 A;  3BIP A;  3FMR A;  3D27 A;  2Q94 A;  2BWU A;  2V3Z A;  3CB5 A;  2GA2 A;  1KP0 A;  2GU7 A;  4R60 A;  4FKC A;  3IG4 A;  1PV9 A;  3IU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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