1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase 1B
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
4PV4A 4FO8A 2BWYA 4IKTA 4U6CA 1WL6A 2B3HA 1C21A 3TB5A 4S2TP 4FLLA 3BIPA 2Q8KA 1KP0A 2OAZA 2Q96A 4RGZ1 4RZYA 2GG3A 3CTZA 4IECA 1WN1A 2GU7A 1W2MA 1YW7A 4A6VA 1JAWA 3IG4A 4S00A 2EA2A 2P9AA 2V3YA 4U70A 3MR1A 2Q92A 3TAVA 3FM3A 3RVAA 4U6JA 3PKCA 4B28A 4U6ZA 4IKRA 3Q6DA 3IU7A 4EGEA 2EA4A 2GGBA 2GZ5A 3MATA 2NQ6A 3CB5A 2BWSA 1YJ3A 2GTXA 2GG8A 1YW9A 2G6PA 1KQ9A 4U75A 1WY2A 1C22A 5CIKA 3BIQA 3PKEA 1XGNA 4U76A 1B59A 1QXWA 1R5GA 1WL9A 1Y1NA 5CNXA 5FCFA 1CHMA 5JI6A 4IKUA 4KM3A 1PV9A 2EVOA 1QZYA 3FMQA 2BWUA 1C23A 3L24A 2BWXA 3S6BA 1KQ0A 4IF7A 1XGOA 2V6CA 1YVMA 2GG5A 4FLIA 4JUQA 4U6WA 4S01A 4R60A 3BITA 4IU6A 1YW8A 2GG9A 2GA2A 4S2RP 2EVMA 4IPAA 1WBQA 2DFIA 5D6FA 3PKAA 2P99A 2V3ZA 4OOKA 4FKCA 1C27A 5CDEA 2BHAA 4ZWUA 2IW2A 2GU6A 3PKBA 4QR8A 3RORA 1MATA 1QXZA 2BB7A 3PKDA 5D6EA 1WKMA 1R58A 5CDLA 1M35A 2GU4A 5FCHA 5JFRA 4U1BA 2P98A 2BH3A 4U6EA 2B3KA 2BWTA 3D27A 4U69A 1C24A 2BHCA 2Q94A 2NQ7A 5E5BA 2ADUA 4MATA 2BHDA 1XNZA 5JHUA 4IKSA 4ZWPA 2GGCA 2GG0A 1XGMA 4FUKA 4A6WA 4FO7A 2MATA 4HXXA 2Q93A 1BN5A 2GG2A 1QXYA 1XGSA 1N51A 2EVCA 5CLSA 5CE6A 5CDVA 4RZZA 2ZSGA 4Z7MA 2GG7A 2B3LA 3CB6A 1WLRA 4U71A 4ZWOA 1BOAA 2BN7A 2V3XA 4FLJA 4IDYA 3MX6A 2BWVA 4ZNGA 4PNCA 3FMRA 3IU8A 1R5HA 2BHBA 2GU5A 2BWWA 2HOWA 1O0XA 1W7VA 3IU9A 2Q95A 4FLKA 1A16A 4U73A 2OKNA 3L7GA 1B6AA
chains in the Genus database with same CATH superfamily
4PV4A 4FO8A 2BWYA 4IKTA 4U6CA 1WL6A 2B3HA 1C21A 3TB5A 4S2TP 4FLLA 3BIPA 2Q8KA 1KP0A 2OAZA 2Q96A 4RGZ1 4RZYA 2GG3A 3CTZA 4IECA 1WN1A 2GU7A 1W2MA 1YW7A 4A6VA 1JAWA 3IG4A 4S00A 2EA2A 2P9AA 2V3YA 4U70A 3MR1A 2Q92A 3TAVA 3FM3A 3RVAA 4U6JA 3PKCA 4B28A 4U6ZA 4IKRA 3Q6DA 3IU7A 4EGEA 2EA4A 2GGBA 2GZ5A 3MATA 2NQ6A 3CB5A 2BWSA 1YJ3A 2GTXA 2GG8A 1YW9A 2G6PA 1KQ9A 4U75A 1WY2A 1C22A 5CIKA 3BIQA 3PKEA 1XGNA 4U76A 1B59A 1QXWA 1R5GA 1WL9A 1Y1NA 5CNXA 5FCFA 1CHMA 5JI6A 4IKUA 4KM3A 1PV9A 2EVOA 1QZYA 3FMQA 2BWUA 1C23A 3L24A 2BWXA 3S6BA 1KQ0A 4IF7A 1XGOA 2V6CA 1YVMA 2GG5A 4FLIA 4JUQA 4U6WA 4S01A 4R60A 3BITA 4IU6A 1YW8A 2GG9A 2GA2A 4S2RP 2EVMA 4IPAA 1WBQA 2DFIA 5D6FA 3PKAA 2P99A 2V3ZA 4OOKA 4FKCA 1C27A 5CDEA 2BHAA 4ZWUA 2IW2A 2GU6A 3PKBA 4QR8A 3RORA 1MATA 1QXZA 2BB7A 3PKDA 5D6EA 1WKMA 1R58A 5CDLA 1M35A 2GU4A 5FCHA 5JFRA 4U1BA 2P98A 2BH3A 4U6EA 2B3KA 2BWTA 3D27A 4U69A 1C24A 2BHCA 2Q94A 2NQ7A 5E5BA 2ADUA 4MATA 2BHDA 1XNZA 5JHUA 4IKSA 4ZWPA 2GGCA 2GG0A 1XGMA 4FUKA 4A6WA 4FO7A 2MATA 4HXXA 2Q93A 1BN5A 2GG2A 1QXYA 1XGSA 1N51A 2EVCA 5CLSA 5CE6A 5CDVA 4RZZA 2ZSGA 4Z7MA 2GG7A 2B3LA 3CB6A 1WLRA 4U71A 4ZWOA 1BOAA 2BN7A 2V3XA 4FLJA 4IDYA 3MX6A 2BWVA 4ZNGA 4PNCA 3FMRA 3IU8A 1R5HA 2BHBA 2GU5A 2BWWA 2HOWA 1O0XA 1W7VA 3IU9A 2Q95A 4FLKA 1A16A 4U73A 2OKNA 3L7GA 1B6AA
chains in the Genus database with same CATH topology
4PV4A 4FO8A 2BWYA 4IKTA 4U6CA 1WL6A 2B3HA 1C21A 3TB5A 4S2TP 4FLLA 3BIPA 2Q8KA 1KP0A 2OAZA 2Q96A 4RGZ1 4RZYA 2GG3A 3CTZA 4IECA 1WN1A 2GU7A 1W2MA 1YW7A 4A6VA 1JAWA 3IG4A 4S00A 2EA2A 2P9AA 2V3YA 4U70A 3MR1A 2Q92A 3TAVA 3FM3A 3RVAA 4U6JA 3PKCA 4B28A 4U6ZA 4IKRA 3Q6DA 3IU7A 4EGEA 2EA4A 2GGBA 2GZ5A 3MATA 2NQ6A 3CB5A 2BWSA 1YJ3A 2GTXA 2GG8A 1YW9A 2G6PA 1KQ9A 4U75A 1WY2A 1C22A 5CIKA 3BIQA 3PKEA 1XGNA 4U76A 1B59A 1QXWA 1R5GA 1WL9A 1Y1NA 5CNXA 5FCFA 1CHMA 5JI6A 4IKUA 4KM3A 1PV9A 2EVOA 1QZYA 3FMQA 2BWUA 1C23A 3L24A 2BWXA 3S6BA 1KQ0A 4IF7A 1XGOA 2V6CA 1YVMA 2GG5A 4FLIA 4JUQA 4U6WA 4S01A 4R60A 3BITA 4IU6A 1YW8A 2GG9A 2GA2A 4S2RP 2EVMA 4IPAA 1WBQA 2DFIA 5D6FA 3PKAA 2P99A 2V3ZA 4OOKA 4FKCA 1C27A 5CDEA 2BHAA 4ZWUA 2IW2A 2GU6A 3PKBA 4QR8A 3RORA 1MATA 1QXZA 2BB7A 3PKDA 5D6EA 1WKMA 1R58A 5CDLA 1M35A 2GU4A 5FCHA 5JFRA 4U1BA 2P98A 2BH3A 4U6EA 2B3KA 2BWTA 3D27A 4U69A 1C24A 2BHCA 2Q94A 2NQ7A 5E5BA 2ADUA 4MATA 2BHDA 1XNZA 5JHUA 4IKSA 4ZWPA 2GGCA 2GG0A 1XGMA 4FUKA 4A6WA 4FO7A 2MATA 4HXXA 2Q93A 1BN5A 2GG2A 1QXYA 1XGSA 1N51A 2EVCA 5CLSA 5CE6A 5CDVA 4RZZA 2ZSGA 4Z7MA 2GG7A 2B3LA 3CB6A 1WLRA 4U71A 4ZWOA 1BOAA 2BN7A 2V3XA 4FLJA 4IDYA 3MX6A 2BWVA 4ZNGA 4PNCA 3FMRA 3IU8A 1R5HA 2BHBA 2GU5A 2BWWA 2HOWA 1O0XA 1W7VA 3IU9A 2Q95A 4FLKA 1A16A 4U73A 2OKNA 3L7GA 1B6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PV4 A;  4FO8 A;  2BWY A;  4IKT A;  4U6C A;  1WL6 A;  2B3H A;  1C21 A;  3TB5 A;  4S2T P;  4FLL A;  3BIP A;  2Q8K A;  1KP0 A;  2OAZ A;  2Q96 A;  4RGZ 1;  4RZY A;  2GG3 A;  3CTZ A;  4IEC A;  1WN1 A;  2GU7 A;  1W2M A;  1YW7 A;  4A6V A;  1JAW A;  3IG4 A;  4S00 A;  2EA2 A;  2P9A A;  2V3Y A;  4U70 A;  3MR1 A;  2Q92 A;  3TAV A;  3FM3 A;  3RVA A;  4U6J A;  3PKC A;  4B28 A;  4U6Z A;  4IKR A;  3Q6D A;  3IU7 A;  4EGE A;  2EA4 A;  2GGB A;  2GZ5 A;  3MAT A;  2NQ6 A;  3CB5 A;  2BWS A;  1YJ3 A;  2GTX A;  2GG8 A;  1YW9 A;  2G6P A;  1KQ9 A;  4U75 A;  1WY2 A;  1C22 A;  5CIK A;  3BIQ A;  3PKE A;  1XGN A;  4U76 A;  1B59 A;  1QXW A;  1R5G A;  1WL9 A;  1Y1N A;  5CNX A;  5FCF A;  1CHM A;  5JI6 A;  4IKU A;  4KM3 A;  1PV9 A;  2EVO A;  1QZY A;  3FMQ A;  2BWU A;  1C23 A;  3L24 A;  2BWX A;  3S6B A;  1KQ0 A;  4IF7 A;  1XGO A;  2V6C A;  1YVM A;  2GG5 A;  4FLI A;  4JUQ A;  4U6W A;  4S01 A;  4R60 A;  3BIT A;  4IU6 A;  1YW8 A;  2GG9 A;  2GA2 A;  4S2R P;  2EVM A;  4IPA A;  1WBQ A;  2DFI A;  5D6F A;  3PKA A;  2P99 A;  2V3Z A;  4OOK A;  4FKC A;  1C27 A;  5CDE A;  2BHA A;  4ZWU A;  2IW2 A;  2GU6 A;  3PKB A;  4QR8 A;  3ROR A;  1MAT A;  1QXZ A;  2BB7 A;  3PKD A;  5D6E A;  1WKM A;  1R58 A;  5CDL A;  1M35 A;  2GU4 A;  5FCH A;  5JFR A;  4U1B A;  2P98 A;  2BH3 A;  4U6E A;  2B3K A;  2BWT A;  3D27 A;  4U69 A;  1C24 A;  2BHC A;  2Q94 A;  2NQ7 A;  5E5B A;  2ADU A;  4MAT A;  2BHD A;  1XNZ A;  5JHU A;  4IKS A;  4ZWP A;  2GGC A;  2GG0 A;  1XGM A;  4FUK A;  4A6W A;  4FO7 A;  2MAT A;  4HXX A;  2Q93 A;  1BN5 A;  2GG2 A;  1QXY A;  1XGS A;  1N51 A;  2EVC A;  5CLS A;  5CE6 A;  5CDV A;  4RZZ A;  2ZSG A;  4Z7M A;  2GG7 A;  2B3L A;  3CB6 A;  1WLR A;  4U71 A;  4ZWO A;  1BOA A;  2BN7 A;  2V3X A;  4FLJ A;  4IDY A;  3MX6 A;  2BWV A;  4ZNG A;  4PNC A;  3FMR A;  3IU8 A;  1R5H A;  2BHB A;  2GU5 A;  2BWW A;  2HOW A;  1O0X A;  1W7V A;  3IU9 A;  2Q95 A;  4FLK A;  1A16 A;  4U73 A;  2OKN A;  3L7G A;  1B6A A; 
#chains in the Genus database with same CATH topology
 4PV4 A;  4FO8 A;  2BWY A;  4IKT A;  4U6C A;  1WL6 A;  2B3H A;  1C21 A;  3TB5 A;  4S2T P;  4FLL A;  3BIP A;  2Q8K A;  1KP0 A;  2OAZ A;  2Q96 A;  4RGZ 1;  4RZY A;  2GG3 A;  3CTZ A;  4IEC A;  1WN1 A;  2GU7 A;  1W2M A;  1YW7 A;  4A6V A;  1JAW A;  3IG4 A;  4S00 A;  2EA2 A;  2P9A A;  2V3Y A;  4U70 A;  3MR1 A;  2Q92 A;  3TAV A;  3FM3 A;  3RVA A;  4U6J A;  3PKC A;  4B28 A;  4U6Z A;  4IKR A;  3Q6D A;  3IU7 A;  4EGE A;  2EA4 A;  2GGB A;  2GZ5 A;  3MAT A;  2NQ6 A;  3CB5 A;  2BWS A;  1YJ3 A;  2GTX A;  2GG8 A;  1YW9 A;  2G6P A;  1KQ9 A;  4U75 A;  1WY2 A;  1C22 A;  5CIK A;  3BIQ A;  3PKE A;  1XGN A;  4U76 A;  1B59 A;  1QXW A;  1R5G A;  1WL9 A;  1Y1N A;  5CNX A;  5FCF A;  1CHM A;  5JI6 A;  4IKU A;  4KM3 A;  1PV9 A;  2EVO A;  1QZY A;  3FMQ A;  2BWU A;  1C23 A;  3L24 A;  2BWX A;  3S6B A;  1KQ0 A;  4IF7 A;  1XGO A;  2V6C A;  1YVM A;  2GG5 A;  4FLI A;  4JUQ A;  4U6W A;  4S01 A;  4R60 A;  3BIT A;  4IU6 A;  1YW8 A;  2GG9 A;  2GA2 A;  4S2R P;  2EVM A;  4IPA A;  1WBQ A;  2DFI A;  5D6F A;  3PKA A;  2P99 A;  2V3Z A;  4OOK A;  4FKC A;  1C27 A;  5CDE A;  2BHA A;  4ZWU A;  2IW2 A;  2GU6 A;  3PKB A;  4QR8 A;  3ROR A;  1MAT A;  1QXZ A;  2BB7 A;  3PKD A;  5D6E A;  1WKM A;  1R58 A;  5CDL A;  1M35 A;  2GU4 A;  5FCH A;  5JFR A;  4U1B A;  2P98 A;  2BH3 A;  4U6E A;  2B3K A;  2BWT A;  3D27 A;  4U69 A;  1C24 A;  2BHC A;  2Q94 A;  2NQ7 A;  5E5B A;  2ADU A;  4MAT A;  2BHD A;  1XNZ A;  5JHU A;  4IKS A;  4ZWP A;  2GGC A;  2GG0 A;  1XGM A;  4FUK A;  4A6W A;  4FO7 A;  2MAT A;  4HXX A;  2Q93 A;  1BN5 A;  2GG2 A;  1QXY A;  1XGS A;  1N51 A;  2EVC A;  5CLS A;  5CE6 A;  5CDV A;  4RZZ A;  2ZSG A;  4Z7M A;  2GG7 A;  2B3L A;  3CB6 A;  1WLR A;  4U71 A;  4ZWO A;  1BOA A;  2BN7 A;  2V3X A;  4FLJ A;  4IDY A;  3MX6 A;  2BWV A;  4ZNG A;  4PNC A;  3FMR A;  3IU8 A;  1R5H A;  2BHB A;  2GU5 A;  2BWW A;  2HOW A;  1O0X A;  1W7V A;  3IU9 A;  2Q95 A;  4FLK A;  1A16 A;  4U73 A;  2OKN A;  3L7G A;  1B6A A; 
#chains in the Genus database with same CATH homology
 4PV4 A;  4FO8 A;  2BWY A;  4IKT A;  4U6C A;  1WL6 A;  2B3H A;  1C21 A;  3TB5 A;  4S2T P;  4FLL A;  3BIP A;  2Q8K A;  1KP0 A;  2OAZ A;  2Q96 A;  4RGZ 1;  4RZY A;  2GG3 A;  3CTZ A;  4IEC A;  1WN1 A;  2GU7 A;  1W2M A;  1YW7 A;  4A6V A;  1JAW A;  3IG4 A;  4S00 A;  2EA2 A;  2P9A A;  2V3Y A;  4U70 A;  3MR1 A;  2Q92 A;  3TAV A;  3FM3 A;  3RVA A;  4U6J A;  3PKC A;  4B28 A;  4U6Z A;  4IKR A;  3Q6D A;  3IU7 A;  4EGE A;  2EA4 A;  2GGB A;  2GZ5 A;  3MAT A;  2NQ6 A;  3CB5 A;  2BWS A;  1YJ3 A;  2GTX A;  2GG8 A;  1YW9 A;  2G6P A;  1KQ9 A;  4U75 A;  1WY2 A;  1C22 A;  5CIK A;  3BIQ A;  3PKE A;  1XGN A;  4U76 A;  1B59 A;  1QXW A;  1R5G A;  1WL9 A;  1Y1N A;  5CNX A;  5FCF A;  1CHM A;  5JI6 A;  4IKU A;  4KM3 A;  1PV9 A;  2EVO A;  1QZY A;  3FMQ A;  2BWU A;  1C23 A;  3L24 A;  2BWX A;  3S6B A;  1KQ0 A;  4IF7 A;  1XGO A;  2V6C A;  1YVM A;  2GG5 A;  4FLI A;  4JUQ A;  4U6W A;  4S01 A;  4R60 A;  3BIT A;  4IU6 A;  1YW8 A;  2GG9 A;  2GA2 A;  4S2R P;  2EVM A;  4IPA A;  1WBQ A;  2DFI A;  5D6F A;  3PKA A;  2P99 A;  2V3Z A;  4OOK A;  4FKC A;  1C27 A;  5CDE A;  2BHA A;  4ZWU A;  2IW2 A;  2GU6 A;  3PKB A;  4QR8 A;  3ROR A;  1MAT A;  1QXZ A;  2BB7 A;  3PKD A;  5D6E A;  1WKM A;  1R58 A;  5CDL A;  1M35 A;  2GU4 A;  5FCH A;  5JFR A;  4U1B A;  2P98 A;  2BH3 A;  4U6E A;  2B3K A;  2BWT A;  3D27 A;  4U69 A;  1C24 A;  2BHC A;  2Q94 A;  2NQ7 A;  5E5B A;  2ADU A;  4MAT A;  2BHD A;  1XNZ A;  5JHU A;  4IKS A;  4ZWP A;  2GGC A;  2GG0 A;  1XGM A;  4FUK A;  4A6W A;  4FO7 A;  2MAT A;  4HXX A;  2Q93 A;  1BN5 A;  2GG2 A;  1QXY A;  1XGS A;  1N51 A;  2EVC A;  5CLS A;  5CE6 A;  5CDV A;  4RZZ A;  2ZSG A;  4Z7M A;  2GG7 A;  2B3L A;  3CB6 A;  1WLR A;  4U71 A;  4ZWO A;  1BOA A;  2BN7 A;  2V3X A;  4FLJ A;  4IDY A;  3MX6 A;  2BWV A;  4ZNG A;  4PNC A;  3FMR A;  3IU8 A;  1R5H A;  2BHB A;  2GU5 A;  2BWW A;  2HOW A;  1O0X A;  1W7V A;  3IU9 A;  2Q95 A;  4FLK A;  1A16 A;  4U73 A;  2OKN A;  3L7G A;  1B6A A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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