1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase 1B
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
2B3HA 1XNZA 2B3KA 3S6BA 5FCHA 5E5BA 2BWWA 1JAWA 4U6JA 1R58A 2G6PA 4FO8A 2EVMA 2BHBA 1M35A 3FMRA 2EVOA 2GGCA 3RVAA 4U6ZA 2Q95A 1QXWA 3CB6A 4IKUA 1C23A 2P98A 4IPAA 2B3LA 1QZYA 4Z7MA 5CLSA 1XGMA 2OAZA 1PV9A 4FO7A 3CTZA 1C22A 4MATA 1B59A 1MATA 4IF7A 2P9AA 2V3ZA 4U71A 5CE6A 4PNCA 2BH3A 4S00A 5CDLA 5FCFA 1B6AA 4S2TP 1BOAA 3FM3A 4R60A 1YVMA 2GG5A 4OOKA 2MATA 1O0XA 4FLIA 4RZZA 4FLKA 1XGNA 1WBQA 4KM3A 2EVCA 2GU5A 5CNXA 2BWUA 2Q93A 4FUKA 4U73A 5D6EA 3CB5A 3D27A 4ZNGA 2GG2A 1WY2A 2ZSGA 1YW9A 3BIQA 2ADUA 2V6CA 2NQ7A 2P99A 3PKAA 2Q96A 1Y1NA 4HXXA 3IU8A 1QXZA 3IU7A 4FLJA 2BWXA 4IKTA 5CDVA 4U6EA 4U6WA 4U76A 2BN7A 4IKRA 4IECA 1YJ3A 4FLLA 4IDYA 4U1BA 4RZYA 3PKEA 1CHMA 4ZWUA 4B28A 2V3YA 1R5GA 4QR8A 3MATA 1KQ9A 3BIPA 4ZWPA 1KQ0A 3TB5A 2Q8KA 2BHAA 2HOWA 2Q92A 1WKMA 5CIKA 4EGEA 4S01A 3PKBA 1QXYA 2BWVA 4IU6A 3BITA 1WL9A 4RGZ1 4JUQA 2GTXA 3FMQA 2GG9A 3MX6A 2GU7A 3TAVA 4S2RP 1W7VA 1W2MA 1YW8A 3IU9A 2NQ6A 4U69A 2GU4A 5D6FA 1WLRA 2BWTA 1WL6A 1A16A 1YW7A 2EA4A 2GA2A 2GG8A 3L24A 4U70A 2GU6A 4U6CA 5JFRA 4A6WA 2GG0A 2OKNA 2GGBA 4A6VA 3PKCA 2Q94A 1N51A 4U75A 3IG4A 3PKDA 3RORA 1C24A 2EA2A 1WN1A 1R5HA 1C21A 4IKSA 3Q6DA 4FKCA 2BHDA 2BHCA 2GG3A 2IW2A 2BB7A 3MR1A 2BWSA 5CDEA 1XGOA 4PV4A 2GZ5A 2DFIA 1C27A 1KP0A 5JI6A 2GG7A 5JHUA 4ZWOA 3L7GA 1BN5A 1XGSA 2BWYA 2V3XA
chains in the Genus database with same CATH superfamily
2B3HA 1XNZA 2B3KA 3S6BA 5FCHA 5E5BA 2BWWA 1JAWA 4U6JA 1R58A 2G6PA 4FO8A 2EVMA 2BHBA 1M35A 3FMRA 2EVOA 2GGCA 3RVAA 4U6ZA 2Q95A 1QXWA 3CB6A 4IKUA 1C23A 2P98A 4IPAA 2B3LA 1QZYA 4Z7MA 5CLSA 1XGMA 2OAZA 1PV9A 4FO7A 3CTZA 1C22A 4MATA 1B59A 1MATA 4IF7A 2P9AA 2V3ZA 4U71A 5CE6A 4PNCA 2BH3A 4S00A 5CDLA 5FCFA 1B6AA 4S2TP 1BOAA 3FM3A 4R60A 1YVMA 2GG5A 4OOKA 2MATA 1O0XA 4FLIA 4RZZA 4FLKA 1XGNA 1WBQA 4KM3A 2EVCA 2GU5A 5CNXA 2BWUA 2Q93A 4FUKA 4U73A 5D6EA 3CB5A 3D27A 4ZNGA 2GG2A 1WY2A 2ZSGA 1YW9A 3BIQA 2ADUA 2V6CA 2NQ7A 2P99A 3PKAA 2Q96A 1Y1NA 4HXXA 3IU8A 1QXZA 3IU7A 4FLJA 2BWXA 4IKTA 5CDVA 4U6EA 4U6WA 4U76A 2BN7A 4IKRA 4IECA 1YJ3A 4FLLA 4IDYA 4U1BA 4RZYA 3PKEA 1CHMA 4ZWUA 4B28A 2V3YA 1R5GA 4QR8A 3MATA 1KQ9A 3BIPA 4ZWPA 1KQ0A 3TB5A 2Q8KA 2BHAA 2HOWA 2Q92A 1WKMA 5CIKA 4EGEA 4S01A 3PKBA 1QXYA 2BWVA 4IU6A 3BITA 1WL9A 4RGZ1 4JUQA 2GTXA 3FMQA 2GG9A 3MX6A 2GU7A 3TAVA 4S2RP 1W7VA 1W2MA 1YW8A 3IU9A 2NQ6A 4U69A 2GU4A 5D6FA 1WLRA 2BWTA 1WL6A 1A16A 1YW7A 2EA4A 2GA2A 2GG8A 3L24A 4U70A 2GU6A 4U6CA 5JFRA 4A6WA 2GG0A 2OKNA 2GGBA 4A6VA 3PKCA 2Q94A 1N51A 4U75A 3IG4A 3PKDA 3RORA 1C24A 2EA2A 1WN1A 1R5HA 1C21A 4IKSA 3Q6DA 4FKCA 2BHDA 2BHCA 2GG3A 2IW2A 2BB7A 3MR1A 2BWSA 5CDEA 1XGOA 4PV4A 2GZ5A 2DFIA 1C27A 1KP0A 5JI6A 2GG7A 5JHUA 4ZWOA 3L7GA 1BN5A 1XGSA 2BWYA 2V3XA
chains in the Genus database with same CATH topology
2B3HA 1XNZA 2B3KA 3S6BA 5FCHA 5E5BA 2BWWA 1JAWA 4U6JA 1R58A 2G6PA 4FO8A 2EVMA 2BHBA 1M35A 3FMRA 2EVOA 2GGCA 3RVAA 4U6ZA 2Q95A 1QXWA 3CB6A 4IKUA 1C23A 2P98A 4IPAA 2B3LA 1QZYA 4Z7MA 5CLSA 1XGMA 2OAZA 1PV9A 4FO7A 3CTZA 1C22A 4MATA 1B59A 1MATA 4IF7A 2P9AA 2V3ZA 4U71A 5CE6A 4PNCA 2BH3A 4S00A 5CDLA 5FCFA 1B6AA 4S2TP 1BOAA 3FM3A 4R60A 1YVMA 2GG5A 4OOKA 2MATA 1O0XA 4FLIA 4RZZA 4FLKA 1XGNA 1WBQA 4KM3A 2EVCA 2GU5A 5CNXA 2BWUA 2Q93A 4FUKA 4U73A 5D6EA 3CB5A 3D27A 4ZNGA 2GG2A 1WY2A 2ZSGA 1YW9A 3BIQA 2ADUA 2V6CA 2NQ7A 2P99A 3PKAA 2Q96A 1Y1NA 4HXXA 3IU8A 1QXZA 3IU7A 4FLJA 2BWXA 4IKTA 5CDVA 4U6EA 4U6WA 4U76A 2BN7A 4IKRA 4IECA 1YJ3A 4FLLA 4IDYA 4U1BA 4RZYA 3PKEA 1CHMA 4ZWUA 4B28A 2V3YA 1R5GA 4QR8A 3MATA 1KQ9A 3BIPA 4ZWPA 1KQ0A 3TB5A 2Q8KA 2BHAA 2HOWA 2Q92A 1WKMA 5CIKA 4EGEA 4S01A 3PKBA 1QXYA 2BWVA 4IU6A 3BITA 1WL9A 4RGZ1 4JUQA 2GTXA 3FMQA 2GG9A 3MX6A 2GU7A 3TAVA 4S2RP 1W7VA 1W2MA 1YW8A 3IU9A 2NQ6A 4U69A 2GU4A 5D6FA 1WLRA 2BWTA 1WL6A 1A16A 1YW7A 2EA4A 2GA2A 2GG8A 3L24A 4U70A 2GU6A 4U6CA 5JFRA 4A6WA 2GG0A 2OKNA 2GGBA 4A6VA 3PKCA 2Q94A 1N51A 4U75A 3IG4A 3PKDA 3RORA 1C24A 2EA2A 1WN1A 1R5HA 1C21A 4IKSA 3Q6DA 4FKCA 2BHDA 2BHCA 2GG3A 2IW2A 2BB7A 3MR1A 2BWSA 5CDEA 1XGOA 4PV4A 2GZ5A 2DFIA 1C27A 1KP0A 5JI6A 2GG7A 5JHUA 4ZWOA 3L7GA 1BN5A 1XGSA 2BWYA 2V3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B3H A;  1XNZ A;  2B3K A;  3S6B A;  5FCH A;  5E5B A;  2BWW A;  1JAW A;  4U6J A;  1R58 A;  2G6P A;  4FO8 A;  2EVM A;  2BHB A;  1M35 A;  3FMR A;  2EVO A;  2GGC A;  3RVA A;  4U6Z A;  2Q95 A;  1QXW A;  3CB6 A;  4IKU A;  1C23 A;  2P98 A;  4IPA A;  2B3L A;  1QZY A;  4Z7M A;  5CLS A;  1XGM A;  2OAZ A;  1PV9 A;  4FO7 A;  3CTZ A;  1C22 A;  4MAT A;  1B59 A;  1MAT A;  4IF7 A;  2P9A A;  2V3Z A;  4U71 A;  5CE6 A;  4PNC A;  2BH3 A;  4S00 A;  5CDL A;  5FCF A;  1B6A A;  4S2T P;  1BOA A;  3FM3 A;  4R60 A;  1YVM A;  2GG5 A;  4OOK A;  2MAT A;  1O0X A;  4FLI A;  4RZZ A;  4FLK A;  1XGN A;  1WBQ A;  4KM3 A;  2EVC A;  2GU5 A;  5CNX A;  2BWU A;  2Q93 A;  4FUK A;  4U73 A;  5D6E A;  3CB5 A;  3D27 A;  4ZNG A;  2GG2 A;  1WY2 A;  2ZSG A;  1YW9 A;  3BIQ A;  2ADU A;  2V6C A;  2NQ7 A;  2P99 A;  3PKA A;  2Q96 A;  1Y1N A;  4HXX A;  3IU8 A;  1QXZ A;  3IU7 A;  4FLJ A;  2BWX A;  4IKT A;  5CDV A;  4U6E A;  4U6W A;  4U76 A;  2BN7 A;  4IKR A;  4IEC A;  1YJ3 A;  4FLL A;  4IDY A;  4U1B A;  4RZY A;  3PKE A;  1CHM A;  4ZWU A;  4B28 A;  2V3Y A;  1R5G A;  4QR8 A;  3MAT A;  1KQ9 A;  3BIP A;  4ZWP A;  1KQ0 A;  3TB5 A;  2Q8K A;  2BHA A;  2HOW A;  2Q92 A;  1WKM A;  5CIK A;  4EGE A;  4S01 A;  3PKB A;  1QXY A;  2BWV A;  4IU6 A;  3BIT A;  1WL9 A;  4RGZ 1;  4JUQ A;  2GTX A;  3FMQ A;  2GG9 A;  3MX6 A;  2GU7 A;  3TAV A;  4S2R P;  1W7V A;  1W2M A;  1YW8 A;  3IU9 A;  2NQ6 A;  4U69 A;  2GU4 A;  5D6F A;  1WLR A;  2BWT A;  1WL6 A;  1A16 A;  1YW7 A;  2EA4 A;  2GA2 A;  2GG8 A;  3L24 A;  4U70 A;  2GU6 A;  4U6C A;  5JFR A;  4A6W A;  2GG0 A;  2OKN A;  2GGB A;  4A6V A;  3PKC A;  2Q94 A;  1N51 A;  4U75 A;  3IG4 A;  3PKD A;  3ROR A;  1C24 A;  2EA2 A;  1WN1 A;  1R5H A;  1C21 A;  4IKS A;  3Q6D A;  4FKC A;  2BHD A;  2BHC A;  2GG3 A;  2IW2 A;  2BB7 A;  3MR1 A;  2BWS A;  5CDE A;  1XGO A;  4PV4 A;  2GZ5 A;  2DFI A;  1C27 A;  1KP0 A;  5JI6 A;  2GG7 A;  5JHU A;  4ZWO A;  3L7G A;  1BN5 A;  1XGS A;  2BWY A;  2V3X A; 
#chains in the Genus database with same CATH topology
 2B3H A;  1XNZ A;  2B3K A;  3S6B A;  5FCH A;  5E5B A;  2BWW A;  1JAW A;  4U6J A;  1R58 A;  2G6P A;  4FO8 A;  2EVM A;  2BHB A;  1M35 A;  3FMR A;  2EVO A;  2GGC A;  3RVA A;  4U6Z A;  2Q95 A;  1QXW A;  3CB6 A;  4IKU A;  1C23 A;  2P98 A;  4IPA A;  2B3L A;  1QZY A;  4Z7M A;  5CLS A;  1XGM A;  2OAZ A;  1PV9 A;  4FO7 A;  3CTZ A;  1C22 A;  4MAT A;  1B59 A;  1MAT A;  4IF7 A;  2P9A A;  2V3Z A;  4U71 A;  5CE6 A;  4PNC A;  2BH3 A;  4S00 A;  5CDL A;  5FCF A;  1B6A A;  4S2T P;  1BOA A;  3FM3 A;  4R60 A;  1YVM A;  2GG5 A;  4OOK A;  2MAT A;  1O0X A;  4FLI A;  4RZZ A;  4FLK A;  1XGN A;  1WBQ A;  4KM3 A;  2EVC A;  2GU5 A;  5CNX A;  2BWU A;  2Q93 A;  4FUK A;  4U73 A;  5D6E A;  3CB5 A;  3D27 A;  4ZNG A;  2GG2 A;  1WY2 A;  2ZSG A;  1YW9 A;  3BIQ A;  2ADU A;  2V6C A;  2NQ7 A;  2P99 A;  3PKA A;  2Q96 A;  1Y1N A;  4HXX A;  3IU8 A;  1QXZ A;  3IU7 A;  4FLJ A;  2BWX A;  4IKT A;  5CDV A;  4U6E A;  4U6W A;  4U76 A;  2BN7 A;  4IKR A;  4IEC A;  1YJ3 A;  4FLL A;  4IDY A;  4U1B A;  4RZY A;  3PKE A;  1CHM A;  4ZWU A;  4B28 A;  2V3Y A;  1R5G A;  4QR8 A;  3MAT A;  1KQ9 A;  3BIP A;  4ZWP A;  1KQ0 A;  3TB5 A;  2Q8K A;  2BHA A;  2HOW A;  2Q92 A;  1WKM A;  5CIK A;  4EGE A;  4S01 A;  3PKB A;  1QXY A;  2BWV A;  4IU6 A;  3BIT A;  1WL9 A;  4RGZ 1;  4JUQ A;  2GTX A;  3FMQ A;  2GG9 A;  3MX6 A;  2GU7 A;  3TAV A;  4S2R P;  1W7V A;  1W2M A;  1YW8 A;  3IU9 A;  2NQ6 A;  4U69 A;  2GU4 A;  5D6F A;  1WLR A;  2BWT A;  1WL6 A;  1A16 A;  1YW7 A;  2EA4 A;  2GA2 A;  2GG8 A;  3L24 A;  4U70 A;  2GU6 A;  4U6C A;  5JFR A;  4A6W A;  2GG0 A;  2OKN A;  2GGB A;  4A6V A;  3PKC A;  2Q94 A;  1N51 A;  4U75 A;  3IG4 A;  3PKD A;  3ROR A;  1C24 A;  2EA2 A;  1WN1 A;  1R5H A;  1C21 A;  4IKS A;  3Q6D A;  4FKC A;  2BHD A;  2BHC A;  2GG3 A;  2IW2 A;  2BB7 A;  3MR1 A;  2BWS A;  5CDE A;  1XGO A;  4PV4 A;  2GZ5 A;  2DFI A;  1C27 A;  1KP0 A;  5JI6 A;  2GG7 A;  5JHU A;  4ZWO A;  3L7G A;  1BN5 A;  1XGS A;  2BWY A;  2V3X A; 
#chains in the Genus database with same CATH homology
 2B3H A;  1XNZ A;  2B3K A;  3S6B A;  5FCH A;  5E5B A;  2BWW A;  1JAW A;  4U6J A;  1R58 A;  2G6P A;  4FO8 A;  2EVM A;  2BHB A;  1M35 A;  3FMR A;  2EVO A;  2GGC A;  3RVA A;  4U6Z A;  2Q95 A;  1QXW A;  3CB6 A;  4IKU A;  1C23 A;  2P98 A;  4IPA A;  2B3L A;  1QZY A;  4Z7M A;  5CLS A;  1XGM A;  2OAZ A;  1PV9 A;  4FO7 A;  3CTZ A;  1C22 A;  4MAT A;  1B59 A;  1MAT A;  4IF7 A;  2P9A A;  2V3Z A;  4U71 A;  5CE6 A;  4PNC A;  2BH3 A;  4S00 A;  5CDL A;  5FCF A;  1B6A A;  4S2T P;  1BOA A;  3FM3 A;  4R60 A;  1YVM A;  2GG5 A;  4OOK A;  2MAT A;  1O0X A;  4FLI A;  4RZZ A;  4FLK A;  1XGN A;  1WBQ A;  4KM3 A;  2EVC A;  2GU5 A;  5CNX A;  2BWU A;  2Q93 A;  4FUK A;  4U73 A;  5D6E A;  3CB5 A;  3D27 A;  4ZNG A;  2GG2 A;  1WY2 A;  2ZSG A;  1YW9 A;  3BIQ A;  2ADU A;  2V6C A;  2NQ7 A;  2P99 A;  3PKA A;  2Q96 A;  1Y1N A;  4HXX A;  3IU8 A;  1QXZ A;  3IU7 A;  4FLJ A;  2BWX A;  4IKT A;  5CDV A;  4U6E A;  4U6W A;  4U76 A;  2BN7 A;  4IKR A;  4IEC A;  1YJ3 A;  4FLL A;  4IDY A;  4U1B A;  4RZY A;  3PKE A;  1CHM A;  4ZWU A;  4B28 A;  2V3Y A;  1R5G A;  4QR8 A;  3MAT A;  1KQ9 A;  3BIP A;  4ZWP A;  1KQ0 A;  3TB5 A;  2Q8K A;  2BHA A;  2HOW A;  2Q92 A;  1WKM A;  5CIK A;  4EGE A;  4S01 A;  3PKB A;  1QXY A;  2BWV A;  4IU6 A;  3BIT A;  1WL9 A;  4RGZ 1;  4JUQ A;  2GTX A;  3FMQ A;  2GG9 A;  3MX6 A;  2GU7 A;  3TAV A;  4S2R P;  1W7V A;  1W2M A;  1YW8 A;  3IU9 A;  2NQ6 A;  4U69 A;  2GU4 A;  5D6F A;  1WLR A;  2BWT A;  1WL6 A;  1A16 A;  1YW7 A;  2EA4 A;  2GA2 A;  2GG8 A;  3L24 A;  4U70 A;  2GU6 A;  4U6C A;  5JFR A;  4A6W A;  2GG0 A;  2OKN A;  2GGB A;  4A6V A;  3PKC A;  2Q94 A;  1N51 A;  4U75 A;  3IG4 A;  3PKD A;  3ROR A;  1C24 A;  2EA2 A;  1WN1 A;  1R5H A;  1C21 A;  4IKS A;  3Q6D A;  4FKC A;  2BHD A;  2BHC A;  2GG3 A;  2IW2 A;  2BB7 A;  3MR1 A;  2BWS A;  5CDE A;  1XGO A;  4PV4 A;  2GZ5 A;  2DFI A;  1C27 A;  1KP0 A;  5JI6 A;  2GG7 A;  5JHU A;  4ZWO A;  3L7G A;  1BN5 A;  1XGS A;  2BWY A;  2V3X A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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