1Y60A

Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (fae) from methylobacterium extorquens am1 with bound 5,10-methylene tetrahydromethanopterin
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
168
structure length
168
Chain Sequence
AKITKVQVGEALVGDGNEVAHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAADDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRKSATHPFAAN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1
pubmed doi rcsb
molecule tags Lyase
source organism Methylobacterium extorquens
molecule keywords Formaldehyde-activating enzyme fae
total genus 52
structure length 168
sequence length 168
chains with identical sequence B, C, D, E
ec nomenclature ec 4.2.1.147: 5,6,7,8-tetrahydromethanopterin hydro-lyase.
pdb deposition date 2004-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08714 Fae Formaldehyde-activating enzyme (Fae)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Formaldehyde-activating enzyme 1y60A00
1Y5YA 1Y60A
chains in the Genus database with same CATH superfamily
1Z0BA 5JEAB 2JEBA 3WU3A 4DV4E 3GMEA 4PRVA 4OX9E 1NHJA 3M85G 4X64I 1S16A 3J81Q 4HACB 2V2VA 1KKHA 1USUA 1Z5CA 3L7ZB 4LFCE 5IT9Q 4DUZE 4B3TE 2EFGA 3KRNA 2UU9I 4OO1D 4ZVIA 4P52A 4LCHA 1N36I 2CVEA 4USMA 5FWKA 4MU4A 1HNWI 4IZJB 1UDSA 1USVA 4LF5I 2O1TA 4IFDE 4HXZA 4JI5E 1A6FA 4AIDA 3J7AM 4OO1A 1BKNA 5K36C 5C0XC 2C37B 1Z0VA 1UEKA 1ELOA 3T1YI 2A2CA 2E1RA 5LL6R 2PO1A 4DR4E 4UTGA 3F0NA 3LTOA 4BA2A 4JI8E 4DR1E 1IBKE 3B8HA 3QT6A 4BA1A 4JV5E 4DU7A 5BR8I 3GONA 4Z7CA 4DV2I 2X36A 1I94I 3K85A 5LMNI 2DEJA 4R1FA 4NBQA 3ZKBA 1N33E 4ISAA 3V2UC 2VQFE 2F4VE 3H4LA 1FJGE 4DV5E 4DR2E 4JI1E 2UXBE 3PS1A 5FLXC 3D4JA 2HKEA 3GCMA 3PYDA 4JI6I 2HK3A 4MYTA 1VISA 2VESA 4X66I 2IOQA 2PNZA 2UUAE 1XMQI 2C38A 4IS9A 4AQYI 4LCGA 5C0XE 4B3RE 5IWAE 2C39B 4DV4I 4OX9I 1MG7A 2VF3A 1FKAE 4AIMA 2HFUA 3OTOE 1H7SA 3HJCA 4DUZI 4B3TI 3Q6NA 1UDOA 3WU6A 4IZKB 1Z0CA 4DR7E 1XNRE 3J80C 4U3DA 2CGEA 2J7KA 4LF7E 1RR9A 5C0XD 4I3HA 2PO0A 3ZZUA 3M85D 5DRQA 1HNZE 4X65E 4DV3E 3UHMA 3JAMC 3PYEA 5ELWA 5JEAA 4JI5I 4HY1A 1ZM4A 3QT8A 4FW4A 1OYSA 2PNMA 1YH8A 4DV7E 4IZJD 3L7ZA 4JI7I 4M1KA 2LJPA 4FW7A 5DNXA 1XMOI 3DD6A 1RREA 3HULA 2HK2A 3P3CA 4DR4I 2VQEE 3GLLA 1IBMI 3PYFA 4LF6E 2HHHI 3CWVA 4P7AA 1N32E 1IBKI 4IZJA 2X7IA 2AE8A 2CG9A 5FLXQ 4JV5I 1Y60A 1P42A 4DPXA 3P3GA 2O1WA 1KIJA 1N33I 4K0KI 2NN6F 2F4VI 4LF4E 1FJGI 4DV5I 1Z0EA 3K1JA 4JI1I 4DV0E 5DROA 4OO1F 2UXBI 1ZXNA 1HR0E 5JEAC 2DEIA 1QZRA 3P06A 2WNRB 3CDJA 4DR6E 3P3EA 2A2DA 4B3ME 1U2RA 4LF9I 4GKKE 3Q6MA 4OKGA 3M6AA 4LFBI 2UUAI 2AJ4A 4DPTA 5L3JA 2PO2B 4JYAE 1N0UA 3ZKDA 5LMUE 2HKJA 4B3RI 1HNXE 2F1DA 2IOPA 1IBLI 4DXLA 1Y6ZA 1Y4SA 3OTOI 4MDTA 3LNUA 1EA6A 2WP8B 4OZEA 3JAMQ 4DUYE 4WUBA 4DR7I 4JI0E 4YHHE 2ZM6E 1XNRI 4IFDF 2V8PA 3J7AG 2R3VA 2JEAB 1Z0GA 3PS3A 4N3OA 4Z7YA 2UXDE 1HNZI 2NN6B 4DV3I 1OYRA 4JI2E 4MQYA 2Z5EA 4ED4A 4OO1B 2BA1G 3PRYA 2C39A 2HFSA 5DNLA 4FN5A 4MU1A 2NPFA 5JEAE 4QNJA 1D6TA 2JT2A 2UXCE 4JI3I 3Q1QA 4KHPE 2UUCI 2UU9E 3CDIA 4NXME 4WUDA 1ZXMA 4FWGA 5DRRA 1Z0TA 3B4TA 4LF8E 2UUBE 4LF6I 1PKPA 1E3HA 3B78A 4BA1B 3V5RA 4DV6E 4LFCI 5JEAD 3U1YA 1XXEA 1DARA 2BA0G 3T1HE 4DV1E 1N34E 4IFDB 2Z5CB 4LOMA 5EL9A 3T1YE 2JE6B 4NXNE 4YY3E 4DV0I 3U1KA 5EKWA 3ZZTA 4DR6I 5K36F 5C0XF 1NHHA 1XHKA 2GO4A 4HYMA 5DRPA 4GKKI 4HACA 2BM0A 2O1VA 2XEXA 4JG4A 4B3SE 4GQUA 1S4EA 4LFAE 1PIEA 1J5EE 1R6MA 1UDNA 2Z5BB 4DR3E 4JI8I 2O3ZA 4GKJE 1Y4UA 2GO3A 4DR1I 1K47A 4RPFA 4DPYA 4FW3A 4YHHI 2ZM6I 2NN6E 1HK7A 3B82A 2WNRA 1ZM3A 4URLA 1XNQE 1YHCA 4DR5E 2VQFI 2UXDI 2C37A 1H74A 4DR2I 4JI2I 1VI7A 4FW9A 2PO2A 1R6LA 2GS8A 4EMDA 1NZ0A 2BR2B 1KTVA 5K36B 1B62A 5C0XB 1OJ4A 3WU4A 2NN6D 2V34A 2UXCI 4KHPI 1OYPA 1WUUA 2JEBB 4KQVA 2WP8A 2E5LE 4PRXA 4JI4E 4NXMI 2V2QA 4LF8I 3J80Q 4FW6A 4X62E 5IWAI 2UUBI 2BA1D 2JEAA 4DPUA 3K17A 3QT7A 4DV6I 2PNLA 2NN6A 4MU0A 4DU8A 3T1HI 4DV1I 1N34I 4JI7E 4LF7I 1XMOE 2ZBKB 1Z59A 1Z0WA 4NXNI 4YY3I 4X65I 5A2QC 1ZM2A 3H1CA 1IBME 4IFDD 2Q2EB 4X64E 2HHHE 4FWHA 2BA0D 3P76A 2V2ZA 2BV3A 3NZKA 4DV7I 3PYGA 2PO1B 4WUCA 1N36E 4B3SI 4BA2B 4IZKA 3J81C 4LFAI 1NHIA 2ZITA 1J5EI 4IFDA 4DR3I 5GMDA 2Z5CA 2VQEI 5GMEA 4K0KE 1FWLA 4FW5A 5IT9C 1HNWE 4GKJI 3M7ND 3PS2A 2JE6A 4LF5E 1H72C 4LPFA 1FI4A 1KVKA 2J65A 1N32I 2NN6C 1ZM9A 4J3DA 2BM1A 4MYUA 4UT4A 4OO1C 1Y5YA 4LF9E 4LFBE 1FNMA 2CZ9A 1XNQI 4U3BA 5JEAF 4DR5I 5K36E 2O1UA 2OI2A 4LF4I 1MX0A 4DPWA 1IBLE 1HR0I 2Z5BA 3WU5A 1N0VC 3M7NG 4XTJA 1H73A 2WW4A 4B3MI 4USKA 4AM3A 2PNZB 4PU9A 2C38B 1B63A 1EI1A 4QNKA 2GQ0A 5BR8E 4LCFA 4DV2E 2IESA 2E5LI 1I94E 4JI4I 5LMNE 1FWKA 1E3PA 4JYAI 1UDQA 5LMUI 4IFDC 5K36D 3LPSA 1HNXI 1PVGA 4X62I 1Z5BA 4FWDA 1H7UA 3HKMA 1MU5A 4MU3A 5A2QQ 2R42A 4DUYI 4JI0I 1RHYA 2IERA 3ZZ0A 3ZM7A 3QT5A 4JI6E 2BR2A 2PO0B 5K36A 4JI3E 5C0XA 4X66E 2UUCE 4OO1E 1Z5AA 1XMQE 4AQYE
chains in the Genus database with same CATH topology
1Y5YA 1Y60A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y5Y A;  1Y60 A; 
#chains in the Genus database with same CATH topology
 1Z0B A;  5JEA B;  2JEB A;  3WU3 A;  4DV4 E;  3GME A;  4PRV A;  4OX9 E;  1NHJ A;  3M85 G;  4X64 I;  1S16 A;  3J81 Q;  4HAC B;  2V2V A;  1KKH A;  1USU A;  1Z5C A;  3L7Z B;  4LFC E;  5IT9 Q;  4DUZ E;  4B3T E;  2EFG A;  3KRN A;  2UU9 I;  4OO1 D;  4ZVI A;  4P52 A;  4LCH A;  1N36 I;  2CVE A;  4USM A;  5FWK A;  4MU4 A;  1HNW I;  4IZJ B;  1UDS A;  1USV A;  4LF5 I;  2O1T A;  4IFD E;  4HXZ A;  4JI5 E;  1A6F A;  4AID A;  3J7A M;  4OO1 A;  1BKN A;  5K36 C;  5C0X C;  2C37 B;  1Z0V A;  1UEK A;  1ELO A;  3T1Y I;  2A2C A;  2E1R A;  5LL6 R;  2PO1 A;  4DR4 E;  4UTG A;  3F0N A;  3LTO A;  4BA2 A;  4JI8 E;  4DR1 E;  1IBK E;  3B8H A;  3QT6 A;  4BA1 A;  4JV5 E;  4DU7 A;  5BR8 I;  3GON A;  4Z7C A;  4DV2 I;  2X36 A;  1I94 I;  3K85 A;  5LMN I;  2DEJ A;  4R1F A;  4NBQ A;  3ZKB A;  1N33 E;  4ISA A;  3V2U C;  2VQF E;  2F4V E;  3H4L A;  1FJG E;  4DV5 E;  4DR2 E;  4JI1 E;  2UXB E;  3PS1 A;  5FLX C;  3D4J A;  2HKE A;  3GCM A;  3PYD A;  4JI6 I;  2HK3 A;  4MYT A;  1VIS A;  2VES A;  4X66 I;  2IOQ A;  2PNZ A;  2UUA E;  1XMQ I;  2C38 A;  4IS9 A;  4AQY I;  4LCG A;  5C0X E;  4B3R E;  5IWA E;  2C39 B;  4DV4 I;  4OX9 I;  1MG7 A;  2VF3 A;  1FKA E;  4AIM A;  2HFU A;  3OTO E;  1H7S A;  3HJC A;  4DUZ I;  4B3T I;  3Q6N A;  1UDO A;  3WU6 A;  4IZK B;  1Z0C A;  4DR7 E;  1XNR E;  3J80 C;  4U3D A;  2CGE A;  2J7K A;  4LF7 E;  1RR9 A;  5C0X D;  4I3H A;  2PO0 A;  3ZZU A;  3M85 D;  5DRQ A;  1HNZ E;  4X65 E;  4DV3 E;  3UHM A;  3JAM C;  3PYE A;  5ELW A;  5JEA A;  4JI5 I;  4HY1 A;  1ZM4 A;  3QT8 A;  4FW4 A;  1OYS A;  2PNM A;  1YH8 A;  4DV7 E;  4IZJ D;  3L7Z A;  4JI7 I;  4M1K A;  2LJP A;  4FW7 A;  5DNX A;  1XMO I;  3DD6 A;  1RRE A;  3HUL A;  2HK2 A;  3P3C A;  4DR4 I;  2VQE E;  3GLL A;  1IBM I;  3PYF A;  4LF6 E;  2HHH I;  3CWV A;  4P7A A;  1N32 E;  1IBK I;  4IZJ A;  2X7I A;  2AE8 A;  2CG9 A;  5FLX Q;  4JV5 I;  1Y60 A;  1P42 A;  4DPX A;  3P3G A;  2O1W A;  1KIJ A;  1N33 I;  4K0K I;  2NN6 F;  2F4V I;  4LF4 E;  1FJG I;  4DV5 I;  1Z0E A;  3K1J A;  4JI1 I;  4DV0 E;  5DRO A;  4OO1 F;  2UXB I;  1ZXN A;  1HR0 E;  5JEA C;  2DEI A;  1QZR A;  3P06 A;  2WNR B;  3CDJ A;  4DR6 E;  3P3E A;  2A2D A;  4B3M E;  1U2R A;  4LF9 I;  4GKK E;  3Q6M A;  4OKG A;  3M6A A;  4LFB I;  2UUA I;  2AJ4 A;  4DPT A;  5L3J A;  2PO2 B;  4JYA E;  1N0U A;  3ZKD A;  5LMU E;  2HKJ A;  4B3R I;  1HNX E;  2F1D A;  2IOP A;  1IBL I;  4DXL A;  1Y6Z A;  1Y4S A;  3OTO I;  4MDT A;  3LNU A;  1EA6 A;  2WP8 B;  4OZE A;  3JAM Q;  4DUY E;  4WUB A;  4DR7 I;  4JI0 E;  4YHH E;  2ZM6 E;  1XNR I;  4IFD F;  2V8P A;  3J7A G;  2R3V A;  2JEA B;  1Z0G A;  3PS3 A;  4N3O A;  4Z7Y A;  2UXD E;  1HNZ I;  2NN6 B;  4DV3 I;  1OYR A;  4JI2 E;  4MQY A;  2Z5E A;  4ED4 A;  4OO1 B;  2BA1 G;  3PRY A;  2C39 A;  2HFS A;  5DNL A;  4FN5 A;  4MU1 A;  2NPF A;  5JEA E;  4QNJ A;  1D6T A;  2JT2 A;  2UXC E;  4JI3 I;  3Q1Q A;  4KHP E;  2UUC I;  2UU9 E;  3CDI A;  4NXM E;  4WUD A;  1ZXM A;  4FWG A;  5DRR A;  1Z0T A;  3B4T A;  4LF8 E;  2UUB E;  4LF6 I;  1PKP A;  1E3H A;  3B78 A;  4BA1 B;  3V5R A;  4DV6 E;  4LFC I;  5JEA D;  3U1Y A;  1XXE A;  1DAR A;  2BA0 G;  3T1H E;  4DV1 E;  1N34 E;  4IFD B;  2Z5C B;  4LOM A;  5EL9 A;  3T1Y E;  2JE6 B;  4NXN E;  4YY3 E;  4DV0 I;  3U1K A;  5EKW A;  3ZZT A;  4DR6 I;  5K36 F;  5C0X F;  1NHH A;  1XHK A;  2GO4 A;  4HYM A;  5DRP A;  4GKK I;  4HAC A;  2BM0 A;  2O1V A;  2XEX A;  4JG4 A;  4B3S E;  4GQU A;  1S4E A;  4LFA E;  1PIE A;  1J5E E;  1R6M A;  1UDN A;  2Z5B B;  4DR3 E;  4JI8 I;  2O3Z A;  4GKJ E;  1Y4U A;  2GO3 A;  4DR1 I;  1K47 A;  4RPF A;  4DPY A;  4FW3 A;  4YHH I;  2ZM6 I;  2NN6 E;  1HK7 A;  3B82 A;  2WNR A;  1ZM3 A;  4URL A;  1XNQ E;  1YHC A;  4DR5 E;  2VQF I;  2UXD I;  2C37 A;  1H74 A;  4DR2 I;  4JI2 I;  1VI7 A;  4FW9 A;  2PO2 A;  1R6L A;  2GS8 A;  4EMD A;  1NZ0 A;  2BR2 B;  1KTV A;  5K36 B;  1B62 A;  5C0X B;  1OJ4 A;  3WU4 A;  2NN6 D;  2V34 A;  2UXC I;  4KHP I;  1OYP A;  1WUU A;  2JEB B;  4KQV A;  2WP8 A;  2E5L E;  4PRX A;  4JI4 E;  4NXM I;  2V2Q A;  4LF8 I;  3J80 Q;  4FW6 A;  4X62 E;  5IWA I;  2UUB I;  2BA1 D;  2JEA A;  4DPU A;  3K17 A;  3QT7 A;  4DV6 I;  2PNL A;  2NN6 A;  4MU0 A;  4DU8 A;  3T1H I;  4DV1 I;  1N34 I;  4JI7 E;  4LF7 I;  1XMO E;  2ZBK B;  1Z59 A;  1Z0W A;  4NXN I;  4YY3 I;  4X65 I;  5A2Q C;  1ZM2 A;  3H1C A;  1IBM E;  4IFD D;  2Q2E B;  4X64 E;  2HHH E;  4FWH A;  2BA0 D;  3P76 A;  2V2Z A;  2BV3 A;  3NZK A;  4DV7 I;  3PYG A;  2PO1 B;  4WUC A;  1N36 E;  4B3S I;  4BA2 B;  4IZK A;  3J81 C;  4LFA I;  1NHI A;  2ZIT A;  1J5E I;  4IFD A;  4DR3 I;  5GMD A;  2Z5C A;  2VQE I;  5GME A;  4K0K E;  1FWL A;  4FW5 A;  5IT9 C;  1HNW E;  4GKJ I;  3M7N D;  3PS2 A;  2JE6 A;  4LF5 E;  1H72 C;  4LPF A;  1FI4 A;  1KVK A;  2J65 A;  1N32 I;  2NN6 C;  1ZM9 A;  4J3D A;  2BM1 A;  4MYU A;  4UT4 A;  4OO1 C;  1Y5Y A;  4LF9 E;  4LFB E;  1FNM A;  2CZ9 A;  1XNQ I;  4U3B A;  5JEA F;  4DR5 I;  5K36 E;  2O1U A;  2OI2 A;  4LF4 I;  1MX0 A;  4DPW A;  1IBL E;  1HR0 I;  2Z5B A;  3WU5 A;  1N0V C;  3M7N G;  4XTJ A;  1H73 A;  2WW4 A;  4B3M I;  4USK A;  4AM3 A;  2PNZ B;  4PU9 A;  2C38 B;  1B63 A;  1EI1 A;  4QNK A;  2GQ0 A;  5BR8 E;  4LCF A;  4DV2 E;  2IES A;  2E5L I;  1I94 E;  4JI4 I;  5LMN E;  1FWK A;  1E3P A;  4JYA I;  1UDQ A;  5LMU I;  4IFD C;  5K36 D;  3LPS A;  1HNX I;  1PVG A;  4X62 I;  1Z5B A;  4FWD A;  1H7U A;  3HKM A;  1MU5 A;  4MU3 A;  5A2Q Q;  2R42 A;  4DUY I;  4JI0 I;  1RHY A;  2IER A;  3ZZ0 A;  3ZM7 A;  3QT5 A;  4JI6 E;  2BR2 A;  2PO0 B;  5K36 A;  4JI3 E;  5C0X A;  4X66 E;  2UUC E;  4OO1 E;  1Z5A A;  1XMQ E;  4AQY E; 
#chains in the Genus database with same CATH homology
 1Y5Y A;  1Y60 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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