1Y8XB

Structural basis for recruitment of ubc12 by an e2-binding domain in nedd8's e1
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
92
structure length
92
Chain Sequence
LPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYMQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Ubiquitin-conjugating enzyme E2 M
total genus 18
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 2004-12-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF08825 E2_bind E2 binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.290.20 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3 1y8xB00
1Y8QB 2NVUB 3ONGA 3FN1A 2LQ7A 4W5VB 3KYDB 1Y8RB 3ONHA 1Y8XB 5FQ2B 3KYCB
chains in the Genus database with same CATH superfamily
2ZM6D 4II3A 4NNJA 1N33D 1Y8RB 1XMQD 4LF4D 2UUBD 3J81E 4LF9D 2HHHD 4X66D 2I1SA 4X65D 4DV7D 4DR7D 2ZTBA 3KBGA 1FJGD 4LFCD 4JI0D 4JI5D 1C06A 1H3FA 2F4VD 4LF7D 4X64D 4DR5D 4OX9D 3JAME 5FQ2B 5LMUD 1IBKD 1N32D 2UXCD 4DV1D 1H3EA 5FLXE 4GKJD 4JI8D 4X62D 4DUZD 2VQED 4DV3D 4OUDA 5IT9E 4II2A 1XMOD 5LL6S 1DM9A 1JH3A 1I94D 1N34D 4NXND 4NXMD 4B3SD 5IWAD 2E5LD 4LFBD 3J80E 4DR3D 3T1YD 4JYAD 2JANA 4LF8D 4KHPD 4W5VB 1HR0D 3FN1A 4JI4D 3T1HD 2KTLA 3HP7A 4DV5D 1IBLD 4DR4D 1Y8QB 4DR1D 1HNXD 1HNWD 4JI7D 3KYDB 1VIOA 4LFAD 4B3RD 5KNLA 4JI1D 2VQFD 4DV2D 2UUAD 1C05A 4JI2D 1KSVA 1Y8XB 1HNZD 3KYCB 4AQYD 4JV5D 2K6PA 2UXBD 4B3TD 4LGTA 1IBMD 4JI6D 2UU9D 4DUYD 4DR2D 3CMMA 2NVUB 1XNQD 3DH3A 1KSKA 2LQ7A 1J5ED 4LF6D 3OTOD 1KSLA 4DR6D 1FKAD 1P9KA 4B3MD 2UUCD 2ISTA 4GKKD 4K0KD 3ONGA 1XNRD 4LF5D 5LMND 4YY3D 3J7AF 1N36D 3ONHA 4DV6D 2UXDD 4JI3D 5BR8D 5A2QE 4DV0D 4DV4D 4YHHD
chains in the Genus database with same CATH topology
1Y8QB 2NVUB 3ONGA 3FN1A 2LQ7A 4W5VB 3KYDB 1Y8RB 3ONHA 1Y8XB 5FQ2B 3KYCB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y8Q B;  2NVU B;  3ONG A;  3FN1 A;  2LQ7 A;  4W5V B;  3KYD B;  1Y8R B;  3ONH A;  1Y8X B;  5FQ2 B;  3KYC B; 
#chains in the Genus database with same CATH topology
 2ZM6 D;  4II3 A;  4NNJ A;  1N33 D;  1Y8R B;  1XMQ D;  4LF4 D;  2UUB D;  3J81 E;  4LF9 D;  2HHH D;  4X66 D;  2I1S A;  4X65 D;  4DV7 D;  4DR7 D;  2ZTB A;  3KBG A;  1FJG D;  4LFC D;  4JI0 D;  4JI5 D;  1C06 A;  1H3F A;  2F4V D;  4LF7 D;  4X64 D;  4DR5 D;  4OX9 D;  3JAM E;  5FQ2 B;  5LMU D;  1IBK D;  1N32 D;  2UXC D;  4DV1 D;  1H3E A;  5FLX E;  4GKJ D;  4JI8 D;  4X62 D;  4DUZ D;  2VQE D;  4DV3 D;  4OUD A;  5IT9 E;  4II2 A;  1XMO D;  5LL6 S;  1DM9 A;  1JH3 A;  1I94 D;  1N34 D;  4NXN D;  4NXM D;  4B3S D;  5IWA D;  2E5L D;  4LFB D;  3J80 E;  4DR3 D;  3T1Y D;  4JYA D;  2JAN A;  4LF8 D;  4KHP D;  4W5V B;  1HR0 D;  3FN1 A;  4JI4 D;  3T1H D;  2KTL A;  3HP7 A;  4DV5 D;  1IBL D;  4DR4 D;  1Y8Q B;  4DR1 D;  1HNX D;  1HNW D;  4JI7 D;  3KYD B;  1VIO A;  4LFA D;  4B3R D;  5KNL A;  4JI1 D;  2VQF D;  4DV2 D;  2UUA D;  1C05 A;  4JI2 D;  1KSV A;  1Y8X B;  1HNZ D;  3KYC B;  4AQY D;  4JV5 D;  2K6P A;  2UXB D;  4B3T D;  4LGT A;  1IBM D;  4JI6 D;  2UU9 D;  4DUY D;  4DR2 D;  3CMM A;  2NVU B;  1XNQ D;  3DH3 A;  1KSK A;  2LQ7 A;  1J5E D;  4LF6 D;  3OTO D;  1KSL A;  4DR6 D;  1FKA D;  1P9K A;  4B3M D;  2UUC D;  2IST A;  4GKK D;  4K0K D;  3ONG A;  1XNR D;  4LF5 D;  5LMN D;  4YY3 D;  3J7A F;  1N36 D;  3ONH A;  4DV6 D;  2UXD D;  4JI3 D;  5BR8 D;  5A2Q E;  4DV0 D;  4DV4 D;  4YHH D; 
#chains in the Genus database with same CATH homology
 1Y8Q B;  2NVU B;  3ONG A;  3FN1 A;  2LQ7 A;  4W5V B;  3KYD B;  1Y8R B;  3ONH A;  1Y8X B;  5FQ2 B;  3KYC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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