1YBGA

Mura inhibited by a derivative of 5-sulfonoxy-anthranilic acid
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
419
structure length
418
Chain Sequence
MDKFRVQGPTRLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLTQLGTKVERGSVWIDASNVNNFSAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIFGLEKLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTIIENAAREPEIVDTANFLVALGAKISGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISGGKIVCRNAQPDTLDAVLAKLREAGADIETGEDWISLDMHGKRPKAVTVRTAPHPAFPTDMQAQFTLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA).
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Enterobacter cloacae
molecule keywords UDP-N-acetylglucosamine 1-carboxyvinyltransferase
total genus 127
structure length 418
sequence length 419
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
pdb deposition date 2004-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00275 EPSP_synthase EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 1ybgA02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 1ybgA01
4E7GA 4E7DA 3V4TA 3ZH3A 2O0BA 2PQBA 5BQ2A 3RMTA 3TI2A 3NVSA 4E7EA 1G6SA 4FQDA 2YVWA 1Q36A 3FJZA 1RF6A 2GG4A 3SG1A 3FK0A 1DLGA 2QFTA 3SWQA 3KQJA 1NAWA 2GGDA 5U4HA 3R38A 1X8RA 1P89A 1Q3GA 1RF5A 2PQ9A 2O0EA 2AAYA 3SWIA 3ROIA 3SU9A 1EJDA 2AA9A 3UPKA 3V5VA 4EIIA 2RL2A 2PQDA 4E7CA 4N3PA 3SWDA 1P88A 2QFQA 1EYNA 1G6TA 3SWGA 3FJXA 2O15A 1YBGA 2O0DA 2RL1A 1RF4A 3KR6A 4E7BA 1MI4A 2PQCA 3FK1A 5BUFA 3ISSA 5BS5A 2QFSA 2GGAA 4EGRA 2QFUA 3SLHA 2GG6A 3SWAA 2Z2CA 3VCYA 3ZH4A 2O0XA 1X8TA 4E7FA 1UAEA 4GFPA 1RYWA 4R7UA 3TR1A 2BJBA 3SWEA 1A2NA 3LTHA 3KQAA 4ZNDA 2O0ZA 3SPBA 1EJCA
chains in the Genus database with same CATH superfamily
4E7GA 4E7DA 3V4TA 3ZH3A 2O0BA 2PQBA 5BQ2A 3RMTA 3TI2A 3NVSA 4E7EA 1G6SA 4FQDA 2YVWA 1Q36A 3FJZA 1RF6A 2GG4A 3TUXA 3SG1A 3FK0A 1DLGA 2QFTA 3SWQA 3KQJA 1NAWA 2GGDA 5U4HA 3R38A 1X8RA 1P89A 1Q3GA 1RF5A 2PQ9A 2O0EA 2AAYA 3SWIA 3ROIA 3SU9A 1EJDA 2AA9A 3UPKA 3V5VA 3KGDA 4EIIA 4O89A 2RL2A 2PQDA 4E7CA 4N3PA 3SWDA 3TV1A 1P88A 2QFQA 1EYNA 1G6TA 1QMHA 4CLQA 3SWGA 3FJXA 2O15A 1QMIA 1YBGA 2O0DA 2RL1A 1RF4A 3KR6A 4E7BA 1MI4A 3TUTA 2PQCA 3FK1A 5BUFA 3ISSA 5BS5A 2QFSA 2GGAA 4EGRA 2QFUA 3SLHA 2GG6A 3SWAA 2Z2CA 3VCYA 3ZH4A 2O0XA 3TW3A 1X8TA 4E7FA 1UAEA 4GFPA 1RYWA 4R7UA 3TR1A 2BJBA 3PQVA 3SWEA 1A2NA 3LTHA 3KQAA 4ZNDA 2O0ZA 3SPBA 4O8JA 1EJCA
chains in the Genus database with same CATH topology
4E7GA 4E7DA 3V4TA 3ZH3A 2O0BA 2PQBA 5BQ2A 3RMTA 3TI2A 3NVSA 4E7EA 1G6SA 4FQDA 2YVWA 1Q36A 3FJZA 1RF6A 2GG4A 3SG1A 3FK0A 1DLGA 2QFTA 3SWQA 3KQJA 1NAWA 2GGDA 5U4HA 3R38A 1X8RA 1P89A 1Q3GA 1RF5A 2PQ9A 2O0EA 2AAYA 3SWIA 3ROIA 3SU9A 1EJDA 2AA9A 3UPKA 3V5VA 4EIIA 2RL2A 2PQDA 4E7CA 4N3PA 3SWDA 1P88A 2QFQA 1EYNA 1G6TA 3SWGA 3FJXA 2O15A 1YBGA 2O0DA 2RL1A 1RF4A 3KR6A 4E7BA 1MI4A 2PQCA 3FK1A 5BUFA 3ISSA 5BS5A 2QFSA 2GGAA 4EGRA 2QFUA 3SLHA 2GG6A 3SWAA 2Z2CA 3VCYA 3ZH4A 2O0XA 1X8TA 4E7FA 1UAEA 4GFPA 1RYWA 4R7UA 3TR1A 2BJBA 3SWEA 1A2NA 3LTHA 3KQAA 4ZNDA 2O0ZA 3SPBA 1EJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E7G A;  4E7D A;  3V4T A;  3ZH3 A;  2O0B A;  2PQB A;  5BQ2 A;  3RMT A;  3TI2 A;  3NVS A;  4E7E A;  1G6S A;  4FQD A;  2YVW A;  1Q36 A;  3FJZ A;  1RF6 A;  2GG4 A;  3SG1 A;  3FK0 A;  1DLG A;  2QFT A;  3SWQ A;  3KQJ A;  1NAW A;  2GGD A;  5U4H A;  3R38 A;  1X8R A;  1P89 A;  1Q3G A;  1RF5 A;  2PQ9 A;  2O0E A;  2AAY A;  3SWI A;  3ROI A;  3SU9 A;  1EJD A;  2AA9 A;  3UPK A;  3V5V A;  4EII A;  2RL2 A;  2PQD A;  4E7C A;  4N3P A;  3SWD A;  1P88 A;  2QFQ A;  1EYN A;  1G6T A;  3SWG A;  3FJX A;  2O15 A;  1YBG A;  2O0D A;  2RL1 A;  1RF4 A;  3KR6 A;  4E7B A;  1MI4 A;  2PQC A;  3FK1 A;  5BUF A;  3ISS A;  5BS5 A;  2QFS A;  2GGA A;  4EGR A;  2QFU A;  3SLH A;  2GG6 A;  3SWA A;  2Z2C A;  3VCY A;  3ZH4 A;  2O0X A;  1X8T A;  4E7F A;  1UAE A;  4GFP A;  1RYW A;  4R7U A;  3TR1 A;  2BJB A;  3SWE A;  1A2N A;  3LTH A;  3KQA A;  4ZND A;  2O0Z A;  3SPB A;  1EJC A; 
#chains in the Genus database with same CATH topology
 4E7G A;  4E7D A;  3V4T A;  3ZH3 A;  2O0B A;  2PQB A;  5BQ2 A;  3RMT A;  3TI2 A;  3NVS A;  4E7E A;  1G6S A;  4FQD A;  2YVW A;  1Q36 A;  3FJZ A;  1RF6 A;  2GG4 A;  3TUX A;  3SG1 A;  3FK0 A;  1DLG A;  2QFT A;  3SWQ A;  3KQJ A;  1NAW A;  2GGD A;  5U4H A;  3R38 A;  1X8R A;  1P89 A;  1Q3G A;  1RF5 A;  2PQ9 A;  2O0E A;  2AAY A;  3SWI A;  3ROI A;  3SU9 A;  1EJD A;  2AA9 A;  3UPK A;  3V5V A;  3KGD A;  4EII A;  4O89 A;  2RL2 A;  2PQD A;  4E7C A;  4N3P A;  3SWD A;  3TV1 A;  1P88 A;  2QFQ A;  1EYN A;  1G6T A;  1QMH A;  4CLQ A;  3SWG A;  3FJX A;  2O15 A;  1QMI A;  1YBG A;  2O0D A;  2RL1 A;  1RF4 A;  3KR6 A;  4E7B A;  1MI4 A;  3TUT A;  2PQC A;  3FK1 A;  5BUF A;  3ISS A;  5BS5 A;  2QFS A;  2GGA A;  4EGR A;  2QFU A;  3SLH A;  2GG6 A;  3SWA A;  2Z2C A;  3VCY A;  3ZH4 A;  2O0X A;  3TW3 A;  1X8T A;  4E7F A;  1UAE A;  4GFP A;  1RYW A;  4R7U A;  3TR1 A;  2BJB A;  3PQV A;  3SWE A;  1A2N A;  3LTH A;  3KQA A;  4ZND A;  2O0Z A;  3SPB A;  4O8J A;  1EJC A; 
#chains in the Genus database with same CATH homology
 4E7G A;  4E7D A;  3V4T A;  3ZH3 A;  2O0B A;  2PQB A;  5BQ2 A;  3RMT A;  3TI2 A;  3NVS A;  4E7E A;  1G6S A;  4FQD A;  2YVW A;  1Q36 A;  3FJZ A;  1RF6 A;  2GG4 A;  3SG1 A;  3FK0 A;  1DLG A;  2QFT A;  3SWQ A;  3KQJ A;  1NAW A;  2GGD A;  5U4H A;  3R38 A;  1X8R A;  1P89 A;  1Q3G A;  1RF5 A;  2PQ9 A;  2O0E A;  2AAY A;  3SWI A;  3ROI A;  3SU9 A;  1EJD A;  2AA9 A;  3UPK A;  3V5V A;  4EII A;  2RL2 A;  2PQD A;  4E7C A;  4N3P A;  3SWD A;  1P88 A;  2QFQ A;  1EYN A;  1G6T A;  3SWG A;  3FJX A;  2O15 A;  1YBG A;  2O0D A;  2RL1 A;  1RF4 A;  3KR6 A;  4E7B A;  1MI4 A;  2PQC A;  3FK1 A;  5BUF A;  3ISS A;  5BS5 A;  2QFS A;  2GGA A;  4EGR A;  2QFU A;  3SLH A;  2GG6 A;  3SWA A;  2Z2C A;  3VCY A;  3ZH4 A;  2O0X A;  1X8T A;  4E7F A;  1UAE A;  4GFP A;  1RYW A;  4R7U A;  3TR1 A;  2BJB A;  3SWE A;  1A2N A;  3LTH A;  3KQA A;  4ZND A;  2O0Z A;  3SPB A;  1EJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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