1YFEA

Crystal structure of apo fumarase c from escherichia coli
Total Genus 167
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
167
sequence length
457
structure length
457
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Fumarate hydratase class II
publication title Structure of free fumarase C from Escherichia coli.
pubmed doi rcsb
molecule tags Lyase
total genus 167
structure length 457
sequence length 457
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2004-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1yfeA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1yfeA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1yfeA02
3UNVA 2O78A 2VD6A 4V2QA 1HY1A 1AUWA 1Q5NA 2PTSA 1YISA 1Y2MA 4C5UA 1FUOA 1TJUA 4HGVA 4EEIA 1YFEA 5EYVA 2HVGA 2QGAB 3OCFA 1DCNA 2O7BA 1K62A 4C5RA 3E04A 1GK2A 1RE5A 2O7EA 3R6QA 1B8FA 4FFXA 4C5SA 4BAAA 1GKJA 1TJVA 3NO9A 3RRPA 1FUPA 3C8TA 4C6GA 2X75A 3KDYA 2RJSA 1I0AA 2FUSA 4MX2A 2QVEA 1HY0A 3TV2A 1C3UA 2E9FA 1T6JA 3GTDA 1FUQA 1EB4A 1XWOA 1TJWA 1C3CA 5D6BA 2O6YA 3QBPA 3R6YA 4CQ5A 4APBA 2O7FA 3NZ4A 1VDKA 3GZHA 5F92A 2PFMA 4NLEA 1J3UA 3RD8A 1U15A 1GKMA 4EFCA 4NSLA 1KQ7A 2PTQA 2RJRA 4FLCA 1K7WA 4ADMA 5HW2A 2NYFA 2O7DA 3R6VA 4APAA 1W27A 3CZOA 5EYTA 2NYNA 3KDZA 1JSWA 3BHGA 2OHYA 2PTRA 1TJ7A 4V2RA 2YIIA 1FURA 1YFMA 1GK3A 5F91A 1U16A 1DOFA 4BABA 2J91A 1T6PA 3OCEA 4ADLA
chains in the Genus database with same CATH superfamily
3UNVA 2O78A 2YV5A 1Q91A 2VD6A 2JAWA 4V2QA 1HY1A 1AUWA 1Q5NA 2PTSA 1YISA 1Y2MA 3CRW1 4C5UA 2D27A 4NFLA 1FUOA 1TJUA 4HGVA 4L6AA 4EEIA 1YFEA 5EYVA 2HVGA 3F4SA 3OCFA 2QGAB 1DCNA 2O7BA 3F4TA 1Z4JA 4YIKA 3U19A 1K62A 4C5RA 3E04A 1Z4IA 3BWVA 1GK2A 1RE5A 2O7EA 2JAUA 3R6QA 1B8FA 2JARA 4FFXA 4C5SA 4BAAA 1GKJA 1TJVA 3NO9A 3RRPA 1FUPA 3C8TA 4C6GA 2FELA 2X75A 3KDYA 1Z4MA 2RJSA 1I0AA 2FUSA 4MX2A 3U13A 2QVEA 1HY0A 3CI0K 3TV2A 1C3UA 2E9FA 3CRVA 2D28C 1T6JA 4ADLA 1Z4QA 4L57A 3GTDA 1FUQA 1EB4A 5M0JA 1XWOA 4L6CA 1TJWA 1Q92A 1C3CA 5D6BA 2O6YA 3QBPA 1Z4KA 4E88A 3R6YA 4CQ5A 5H8WA 4APBA 5M0IA 1Z4LA 2O7FA 3NZ4A 1XL8A 2VL7A 1VDKA 3GZHA 3F4RA 1XMCA 5F92A 2PFMA 4IQJM 1XL7A 4NLEA 2JAOA 1J3UA 1U0LA 4WNLA 3RD8A 1U15A 1GKMA 4EFCA 4NSLA 1KQ7A 1XLYA 1Z4PX 2PTQA 2RJRA 4FLCA 1K7WA 1T9HA 4ADMA 5HW2A 4A15A 2I7DA 2NYFA 2O7DA 3R6VA 4YIHA 1MH9A 4APAA 1W27A 3CZOA 1IW7D 5EYTA 2NYNA 3KDZA 4MWOA 1JSWA 3BHGA 2OHYA 2PTRA 1TJ7A 4V2RA 2FENA 2YIIA 1FURA 1YFMA 2RCNA 1GK3A 5F91A 1U16A 1DOFA 4BABA 2J91A 1T6PA 2VSFA 3OCEA 1XMDA 4MUMA
chains in the Genus database with same CATH topology
3UNVA 2O78A 2VD6A 4V2QA 1HY1A 1AUWA 1Q5NA 2PTSA 1YISA 1Y2MA 4C5UA 1FUOA 1TJUA 4HGVA 4EEIA 1YFEA 5EYVA 2HVGA 2QGAB 3OCFA 1DCNA 2O7BA 1K62A 4C5RA 3E04A 1GK2A 1RE5A 2O7EA 3R6QA 1B8FA 4FFXA 4C5SA 4BAAA 1GKJA 1TJVA 3NO9A 3RRPA 1FUPA 3C8TA 4C6GA 2X75A 3KDYA 2RJSA 1I0AA 2FUSA 4MX2A 2QVEA 1HY0A 3TV2A 1C3UA 2E9FA 1T6JA 3GTDA 1FUQA 1EB4A 1XWOA 1TJWA 1C3CA 5D6BA 2O6YA 3QBPA 3R6YA 4CQ5A 4APBA 2O7FA 3NZ4A 1VDKA 3GZHA 5F92A 2PFMA 4NLEA 1J3UA 3RD8A 1U15A 1GKMA 4EFCA 4NSLA 1KQ7A 2PTQA 2RJRA 4FLCA 1K7WA 4ADMA 5HW2A 2NYFA 2O7DA 3R6VA 4APAA 1W27A 3CZOA 5EYTA 2NYNA 3KDZA 1JSWA 3BHGA 2OHYA 2PTRA 1TJ7A 4V2RA 2YIIA 1FURA 1YFMA 1GK3A 5F91A 1U16A 1DOFA 4BABA 2J91A 1T6PA 3OCEA 4ADLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UNV A;  2O78 A;  2VD6 A;  4V2Q A;  1HY1 A;  1AUW A;  1Q5N A;  2PTS A;  1YIS A;  1Y2M A;  4C5U A;  1FUO A;  1TJU A;  4HGV A;  4EEI A;  1YFE A;  5EYV A;  2HVG A;  2QGA B;  3OCF A;  1DCN A;  2O7B A;  1K62 A;  4C5R A;  3E04 A;  1GK2 A;  1RE5 A;  2O7E A;  3R6Q A;  1B8F A;  4FFX A;  4C5S A;  4BAA A;  1GKJ A;  1TJV A;  3NO9 A;  3RRP A;  1FUP A;  3C8T A;  4C6G A;  2X75 A;  3KDY A;  2RJS A;  1I0A A;  2FUS A;  4MX2 A;  2QVE A;  1HY0 A;  3TV2 A;  1C3U A;  2E9F A;  1T6J A;  3GTD A;  1FUQ A;  1EB4 A;  1XWO A;  1TJW A;  1C3C A;  5D6B A;  2O6Y A;  3QBP A;  3R6Y A;  4CQ5 A;  4APB A;  2O7F A;  3NZ4 A;  1VDK A;  3GZH A;  5F92 A;  2PFM A;  4NLE A;  1J3U A;  3RD8 A;  1U15 A;  1GKM A;  4EFC A;  4NSL A;  1KQ7 A;  2PTQ A;  2RJR A;  4FLC A;  1K7W A;  4ADM A;  5HW2 A;  2NYF A;  2O7D A;  3R6V A;  4APA A;  1W27 A;  3CZO A;  5EYT A;  2NYN A;  3KDZ A;  1JSW A;  3BHG A;  2OHY A;  2PTR A;  1TJ7 A;  4V2R A;  2YII A;  1FUR A;  1YFM A;  1GK3 A;  5F91 A;  1U16 A;  1DOF A;  4BAB A;  2J91 A;  1T6P A;  3OCE A;  4ADL A; 
#chains in the Genus database with same CATH topology
 3UNV A;  2O78 A;  2YV5 A;  1Q91 A;  2VD6 A;  2JAW A;  4V2Q A;  1HY1 A;  1AUW A;  1Q5N A;  2PTS A;  1YIS A;  1Y2M A;  3CRW 1;  4C5U A;  2D27 A;  4NFL A;  1FUO A;  1TJU A;  4HGV A;  4L6A A;  4EEI A;  1YFE A;  5EYV A;  2HVG A;  3F4S A;  3OCF A;  2QGA B;  1DCN A;  2O7B A;  3F4T A;  1Z4J A;  4YIK A;  3U19 A;  1K62 A;  4C5R A;  3E04 A;  1Z4I A;  3BWV A;  1GK2 A;  1RE5 A;  2O7E A;  2JAU A;  3R6Q A;  1B8F A;  2JAR A;  4FFX A;  4C5S A;  4BAA A;  1GKJ A;  1TJV A;  3NO9 A;  3RRP A;  1FUP A;  3C8T A;  4C6G A;  2FEL A;  2X75 A;  3KDY A;  1Z4M A;  2RJS A;  1I0A A;  2FUS A;  4MX2 A;  3U13 A;  2QVE A;  1HY0 A;  3CI0 K;  3TV2 A;  1C3U A;  2E9F A;  3CRV A;  2D28 C;  1T6J A;  4ADL A;  1Z4Q A;  4L57 A;  3GTD A;  1FUQ A;  1EB4 A;  5M0J A;  1XWO A;  4L6C A;  1TJW A;  1Q92 A;  1C3C A;  5D6B A;  2O6Y A;  3QBP A;  1Z4K A;  4E88 A;  3R6Y A;  4CQ5 A;  5H8W A;  4APB A;  5M0I A;  1Z4L A;  2O7F A;  3NZ4 A;  1XL8 A;  2VL7 A;  1VDK A;  3GZH A;  3F4R A;  1XMC A;  5F92 A;  2PFM A;  4IQJ M;  1XL7 A;  4NLE A;  2JAO A;  1J3U A;  1U0L A;  4WNL A;  3RD8 A;  1U15 A;  1GKM A;  4EFC A;  4NSL A;  1KQ7 A;  1XLY A;  1Z4P X;  2PTQ A;  2RJR A;  4FLC A;  1K7W A;  1T9H A;  4ADM A;  5HW2 A;  4A15 A;  2I7D A;  2NYF A;  2O7D A;  3R6V A;  4YIH A;  1MH9 A;  4APA A;  1W27 A;  3CZO A;  1IW7 D;  5EYT A;  2NYN A;  3KDZ A;  4MWO A;  1JSW A;  3BHG A;  2OHY A;  2PTR A;  1TJ7 A;  4V2R A;  2FEN A;  2YII A;  1FUR A;  1YFM A;  2RCN A;  1GK3 A;  5F91 A;  1U16 A;  1DOF A;  4BAB A;  2J91 A;  1T6P A;  2VSF A;  3OCE A;  1XMD A;  4MUM A; 
#chains in the Genus database with same CATH homology
 3UNV A;  2O78 A;  2VD6 A;  4V2Q A;  1HY1 A;  1AUW A;  1Q5N A;  2PTS A;  1YIS A;  1Y2M A;  4C5U A;  1FUO A;  1TJU A;  4HGV A;  4EEI A;  1YFE A;  5EYV A;  2HVG A;  2QGA B;  3OCF A;  1DCN A;  2O7B A;  1K62 A;  4C5R A;  3E04 A;  1GK2 A;  1RE5 A;  2O7E A;  3R6Q A;  1B8F A;  4FFX A;  4C5S A;  4BAA A;  1GKJ A;  1TJV A;  3NO9 A;  3RRP A;  1FUP A;  3C8T A;  4C6G A;  2X75 A;  3KDY A;  2RJS A;  1I0A A;  2FUS A;  4MX2 A;  2QVE A;  1HY0 A;  3TV2 A;  1C3U A;  2E9F A;  1T6J A;  3GTD A;  1FUQ A;  1EB4 A;  1XWO A;  1TJW A;  1C3C A;  5D6B A;  2O6Y A;  3QBP A;  3R6Y A;  4CQ5 A;  4APB A;  2O7F A;  3NZ4 A;  1VDK A;  3GZH A;  5F92 A;  2PFM A;  4NLE A;  1J3U A;  3RD8 A;  1U15 A;  1GKM A;  4EFC A;  4NSL A;  1KQ7 A;  2PTQ A;  2RJR A;  4FLC A;  1K7W A;  4ADM A;  5HW2 A;  2NYF A;  2O7D A;  3R6V A;  4APA A;  1W27 A;  3CZO A;  5EYT A;  2NYN A;  3KDZ A;  1JSW A;  3BHG A;  2OHY A;  2PTR A;  1TJ7 A;  4V2R A;  2YII A;  1FUR A;  1YFM A;  1GK3 A;  5F91 A;  1U16 A;  1DOF A;  4BAB A;  2J91 A;  1T6P A;  3OCE A;  4ADL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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