1YFMA

Recombinant yeast fumarase
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
459
structure length
450
Chain Sequence
b'SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEIVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FUMARASE
publication title Crystal structures of native and recombinant yeast fumarase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Lyase
total genus 151
structure length 450
sequence length 459
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1998-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1yfmA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1yfmA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1yfmA02
1FUOA 1VDKA 3NO9A 4C5SA 2NYNA 3BHGA 4C5UA 1TJ7A 4BAAA 3GTDA 3RD8A 1FURA 1TJWA 1Y2MA 3CZOA 3OCEA 4NSLA 2OHYA 1FUQA 1YFEA 3KDZA 4V2RA 2VD6A 2PTRA 5D6BA 1B8FA 1C3UA 1AUWA 2O7EA 4CQ5A 1JSWA 1TJUA 4FLCA 1YISA 3GZHA 2RJRA 4BABA 1HY0A 4EFCA 1RE5A 1GK3A 1K7WA 2X75A 2O7FA 1GKJA 4V2QA 2QVEA 4APBA 1TJVA 1FUPA 1GK2A 1W27A 4NLEA 4APAA 2YIIA 2O6YA 2NYFA 2QGAB 4HGVA 3KDYA 3TV2A 2J91A 3OCFA 4MX2A 1EB4A 5HW2A 1T6JA 4ADLA 1HY1A 2E9FA 1T6PA 1C3CA 4C6GA 1KQ7A 1YFMA 3RRPA 1I0AA 1XWOA 1Q5NA 2O78A 1DCNA 2O7DA 2O7BA 2FUSA 2RJSA 3R6YA 5EYTA 2PTQA 5F91A 2PTSA 1U15A 3R6VA 4C5RA 1K62A 3C8TA 1GKMA 4FFXA 1DOFA 2HVGA 2PFMA 4EEIA 4ADMA 1J3UA 3R6QA 3QBPA 3UNVA 5F92A 3E04A 1U16A 5EYVA 3NZ4A
chains in the Genus database with same CATH superfamily
1FUOA 1IW7D 2JAUA 1VDKA 3NO9A 4C5SA 2NYNA 3BHGA 1U0LA 4C5UA 1TJ7A 1MH9A 4BAAA 3GTDA 3RD8A 1FURA 1Z4PX 1TJWA 1Y2MA 1Z4MA 3CZOA 3OCEA 4NSLA 2OHYA 1FUQA 3CRVA 3F4RA 1XLYA 4YIKA 1YFEA 3KDZA 4V2RA 2RCNA 2VD6A 1Q91A 2PTRA 5M0IA 5D6BA 1B8FA 4NFLA 4IQJM 1C3UA 1AUWA 3F4SA 2O7EA 2JARA 4CQ5A 1JSWA 1TJUA 4FLCA 1YISA 3GZHA 2RJRA 4BABA 4WNLA 1HY0A 4MWOA 4EFCA 5H8WA 1RE5A 1GK3A 1K7WA 2X75A 2O7FA 1GKJA 2YV5A 4L57A 4V2QA 2QVEA 4APBA 1TJVA 4E88A 1FUPA 1GK2A 1W27A 4NLEA 4APAA 2YIIA 2O6YA 2NYFA 2D27A 2QGAB 4HGVA 1Z4JA 3KDYA 3TV2A 2J91A 3OCFA 2I7DA 4MX2A 1EB4A 1XL7A 5HW2A 1T6JA 1Z4LA 3BWVA 5M0JA 2VSFA 3CRW1 4ADLA 1HY1A 2E9FA 1T6PA 2JAOA 2FENA 1C3CA 4C6GA 1KQ7A 1YFMA 3RRPA 1I0AA 1T9HA 1Z4IA 2D28C 4YIHA 1XWOA 1Q5NA 2O78A 1DCNA 1XL8A 2O7DA 2O7BA 2FUSA 2FELA 2RJSA 3R6YA 4MUMA 5EYTA 4A15A 2PTQA 5F91A 1Q92A 2VL7A 3U19A 2PTSA 1U15A 3R6VA 3U13A 4C5RA 1K62A 3C8TA 1GKMA 4FFXA 1XMCA 4L6AA 1DOFA 2HVGA 2JAWA 2PFMA 4EEIA 4ADMA 1J3UA 3F4TA 3R6QA 3QBPA 3UNVA 5F92A 1Z4KA 3E04A 3CI0K 1U16A 4L6CA 1XMDA 5EYVA 1Z4QA 3NZ4A
chains in the Genus database with same CATH topology
1FUOA 1VDKA 3NO9A 4C5SA 2NYNA 3BHGA 4C5UA 1TJ7A 4BAAA 3GTDA 3RD8A 1FURA 1TJWA 1Y2MA 3CZOA 3OCEA 4NSLA 2OHYA 1FUQA 1YFEA 3KDZA 4V2RA 2VD6A 2PTRA 5D6BA 1B8FA 1C3UA 1AUWA 2O7EA 4CQ5A 1JSWA 1TJUA 4FLCA 1YISA 3GZHA 2RJRA 4BABA 1HY0A 4EFCA 1RE5A 1GK3A 1K7WA 2X75A 2O7FA 1GKJA 4V2QA 2QVEA 4APBA 1TJVA 1FUPA 1GK2A 1W27A 4NLEA 4APAA 2YIIA 2O6YA 2NYFA 2QGAB 4HGVA 3KDYA 3TV2A 2J91A 3OCFA 4MX2A 1EB4A 5HW2A 1T6JA 4ADLA 1HY1A 2E9FA 1T6PA 1C3CA 4C6GA 1KQ7A 1YFMA 3RRPA 1I0AA 1XWOA 1Q5NA 2O78A 1DCNA 2O7DA 2O7BA 2FUSA 2RJSA 3R6YA 5EYTA 2PTQA 5F91A 2PTSA 1U15A 3R6VA 4C5RA 1K62A 3C8TA 1GKMA 4FFXA 1DOFA 2HVGA 2PFMA 4EEIA 4ADMA 1J3UA 3R6QA 3QBPA 3UNVA 5F92A 3E04A 1U16A 5EYVA 3NZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FUO A;  1VDK A;  3NO9 A;  4C5S A;  2NYN A;  3BHG A;  4C5U A;  1TJ7 A;  4BAA A;  3GTD A;  3RD8 A;  1FUR A;  1TJW A;  1Y2M A;  3CZO A;  3OCE A;  4NSL A;  2OHY A;  1FUQ A;  1YFE A;  3KDZ A;  4V2R A;  2VD6 A;  2PTR A;  5D6B A;  1B8F A;  1C3U A;  1AUW A;  2O7E A;  4CQ5 A;  1JSW A;  1TJU A;  4FLC A;  1YIS A;  3GZH A;  2RJR A;  4BAB A;  1HY0 A;  4EFC A;  1RE5 A;  1GK3 A;  1K7W A;  2X75 A;  2O7F A;  1GKJ A;  4V2Q A;  2QVE A;  4APB A;  1TJV A;  1FUP A;  1GK2 A;  1W27 A;  4NLE A;  4APA A;  2YII A;  2O6Y A;  2NYF A;  2QGA B;  4HGV A;  3KDY A;  3TV2 A;  2J91 A;  3OCF A;  4MX2 A;  1EB4 A;  5HW2 A;  1T6J A;  4ADL A;  1HY1 A;  2E9F A;  1T6P A;  1C3C A;  4C6G A;  1KQ7 A;  1YFM A;  3RRP A;  1I0A A;  1XWO A;  1Q5N A;  2O78 A;  1DCN A;  2O7D A;  2O7B A;  2FUS A;  2RJS A;  3R6Y A;  5EYT A;  2PTQ A;  5F91 A;  2PTS A;  1U15 A;  3R6V A;  4C5R A;  1K62 A;  3C8T A;  1GKM A;  4FFX A;  1DOF A;  2HVG A;  2PFM A;  4EEI A;  4ADM A;  1J3U A;  3R6Q A;  3QBP A;  3UNV A;  5F92 A;  3E04 A;  1U16 A;  5EYV A;  3NZ4 A; 
#chains in the Genus database with same CATH topology
 1FUO A;  1IW7 D;  2JAU A;  1VDK A;  3NO9 A;  4C5S A;  2NYN A;  3BHG A;  1U0L A;  4C5U A;  1TJ7 A;  1MH9 A;  4BAA A;  3GTD A;  3RD8 A;  1FUR A;  1Z4P X;  1TJW A;  1Y2M A;  1Z4M A;  3CZO A;  3OCE A;  4NSL A;  2OHY A;  1FUQ A;  3CRV A;  3F4R A;  1XLY A;  4YIK A;  1YFE A;  3KDZ A;  4V2R A;  2RCN A;  2VD6 A;  1Q91 A;  2PTR A;  5M0I A;  5D6B A;  1B8F A;  4NFL A;  4IQJ M;  1C3U A;  1AUW A;  3F4S A;  2O7E A;  2JAR A;  4CQ5 A;  1JSW A;  1TJU A;  4FLC A;  1YIS A;  3GZH A;  2RJR A;  4BAB A;  4WNL A;  1HY0 A;  4MWO A;  4EFC A;  5H8W A;  1RE5 A;  1GK3 A;  1K7W A;  2X75 A;  2O7F A;  1GKJ A;  2YV5 A;  4L57 A;  4V2Q A;  2QVE A;  4APB A;  1TJV A;  4E88 A;  1FUP A;  1GK2 A;  1W27 A;  4NLE A;  4APA A;  2YII A;  2O6Y A;  2NYF A;  2D27 A;  2QGA B;  4HGV A;  1Z4J A;  3KDY A;  3TV2 A;  2J91 A;  3OCF A;  2I7D A;  4MX2 A;  1EB4 A;  1XL7 A;  5HW2 A;  1T6J A;  1Z4L A;  3BWV A;  5M0J A;  2VSF A;  3CRW 1;  4ADL A;  1HY1 A;  2E9F A;  1T6P A;  2JAO A;  2FEN A;  1C3C A;  4C6G A;  1KQ7 A;  1YFM A;  3RRP A;  1I0A A;  1T9H A;  1Z4I A;  2D28 C;  4YIH A;  1XWO A;  1Q5N A;  2O78 A;  1DCN A;  1XL8 A;  2O7D A;  2O7B A;  2FUS A;  2FEL A;  2RJS A;  3R6Y A;  4MUM A;  5EYT A;  4A15 A;  2PTQ A;  5F91 A;  1Q92 A;  2VL7 A;  3U19 A;  2PTS A;  1U15 A;  3R6V A;  3U13 A;  4C5R A;  1K62 A;  3C8T A;  1GKM A;  4FFX A;  1XMC A;  4L6A A;  1DOF A;  2HVG A;  2JAW A;  2PFM A;  4EEI A;  4ADM A;  1J3U A;  3F4T A;  3R6Q A;  3QBP A;  3UNV A;  5F92 A;  1Z4K A;  3E04 A;  3CI0 K;  1U16 A;  4L6C A;  1XMD A;  5EYV A;  1Z4Q A;  3NZ4 A; 
#chains in the Genus database with same CATH homology
 1FUO A;  1VDK A;  3NO9 A;  4C5S A;  2NYN A;  3BHG A;  4C5U A;  1TJ7 A;  4BAA A;  3GTD A;  3RD8 A;  1FUR A;  1TJW A;  1Y2M A;  3CZO A;  3OCE A;  4NSL A;  2OHY A;  1FUQ A;  1YFE A;  3KDZ A;  4V2R A;  2VD6 A;  2PTR A;  5D6B A;  1B8F A;  1C3U A;  1AUW A;  2O7E A;  4CQ5 A;  1JSW A;  1TJU A;  4FLC A;  1YIS A;  3GZH A;  2RJR A;  4BAB A;  1HY0 A;  4EFC A;  1RE5 A;  1GK3 A;  1K7W A;  2X75 A;  2O7F A;  1GKJ A;  4V2Q A;  2QVE A;  4APB A;  1TJV A;  1FUP A;  1GK2 A;  1W27 A;  4NLE A;  4APA A;  2YII A;  2O6Y A;  2NYF A;  2QGA B;  4HGV A;  3KDY A;  3TV2 A;  2J91 A;  3OCF A;  4MX2 A;  1EB4 A;  5HW2 A;  1T6J A;  4ADL A;  1HY1 A;  2E9F A;  1T6P A;  1C3C A;  4C6G A;  1KQ7 A;  1YFM A;  3RRP A;  1I0A A;  1XWO A;  1Q5N A;  2O78 A;  1DCN A;  2O7D A;  2O7B A;  2FUS A;  2RJS A;  3R6Y A;  5EYT A;  2PTQ A;  5F91 A;  2PTS A;  1U15 A;  3R6V A;  4C5R A;  1K62 A;  3C8T A;  1GKM A;  4FFX A;  1DOF A;  2HVG A;  2PFM A;  4EEI A;  4ADM A;  1J3U A;  3R6Q A;  3QBP A;  3UNV A;  5F92 A;  3E04 A;  1U16 A;  5EYV A;  3NZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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