1YFMA

Recombinant yeast fumarase
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
459
structure length
450
Chain Sequence
SFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEIVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNRFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKVNPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEGIKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVVPEHML
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords FUMARASE
publication title Crystal structures of native and recombinant yeast fumarase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Lyase
total genus 151
structure length 450
sequence length 459
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1998-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1yfmA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1yfmA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1yfmA02
4C5SA 5EYTA 5F92A 4FFXA 2O7BA 4C5UA 2X75A 4NSLA 1GKMA 3KDZA 3NZ4A 1FUPA 1EB4A 2FUSA 2PTRA 3OCEA 2HVGA 3OCFA 3RD8A 2QVEA 3GTDA 2VD6A 4ADMA 5F91A 4V2QA 3R6QA 1DOFA 2O78A 2O7EA 1TJWA 1W27A 2RJRA 1DCNA 4BAAA 1RE5A 1U15A 2PTQA 2NYNA 4V2RA 1T6PA 1Y2MA 1B8FA 1TJUA 2J91A 2QGAB 1HY0A 1U16A 1KQ7A 3BHGA 2O6YA 1YISA 4CQ5A 3R6YA 5EYVA 2E9FA 1GK3A 1C3CA 3KDYA 2NYFA 4MX2A 1T6JA 4NLEA 1AUWA 3TV2A 4EEIA 1K7WA 4FLCA 3R6VA 1C3UA 2RJSA 3UNVA 1VDKA 1TJVA 4APBA 2YIIA 1K62A 1J3UA 4EFCA 1YFMA 2O7DA 1Q5NA 3QBPA 1FUQA 1FUOA 2PFMA 1GKJA 4C5RA 4HGVA 1TJ7A 2PTSA 1HY1A 4ADLA 1GK2A 1I0AA 3NO9A 1JSWA 5D6BA 2OHYA 4C6GA 3E04A 1FURA 4BABA 5HW2A 3GZHA 1YFEA 2O7FA 1XWOA 3RRPA 3CZOA 3C8TA 4APAA
chains in the Genus database with same CATH superfamily
4C5SA 5EYTA 1Z4KA 5F92A 1IW7D 3BWVA 4FFXA 2O7BA 4C5UA 2X75A 4NSLA 1GKMA 3KDZA 3NZ4A 2FENA 1FUPA 3U13A 1EB4A 3F4TA 2FELA 2FUSA 2PTRA 4YIHA 2VL7A 2YV5A 3OCEA 2JAUA 2JAWA 2HVGA 3OCFA 3RD8A 2QVEA 3GTDA 2VD6A 5H8WA 4ADMA 5F91A 4V2QA 4A15A 3R6QA 1XMDA 1DOFA 1Z4JA 2O78A 2O7EA 1TJWA 4L6CA 1W27A 2RJRA 4YIKA 1DCNA 2JARA 4BAAA 1RE5A 1U15A 2PTQA 2NYNA 4V2RA 1T6PA 1Y2MA 1B8FA 1TJUA 2J91A 2QGAB 1HY0A 1U16A 1KQ7A 1XL7A 3BHGA 2O6YA 1YISA 4CQ5A 3U19A 3R6YA 5EYVA 2E9FA 1Z4LA 1GK3A 1C3CA 3CRVA 3KDYA 2NYFA 4MWOA 1Q92A 1Z4MA 4MX2A 1T6JA 4NLEA 3F4RA 1AUWA 4L57A 3TV2A 1T9HA 1XL8A 1XMCA 2RCNA 4MUMA 1K7WA 4EEIA 2D28C 4FLCA 1XLYA 3R6VA 4IQJM 1C3UA 2RJSA 3UNVA 1VDKA 4WNLA 1TJVA 4APBA 1Z4QA 2YIIA 1K62A 1J3UA 4EFCA 1YFMA 2O7DA 1Q5NA 3QBPA 1FUQA 1FUOA 2PFMA 1GKJA 4C5RA 4HGVA 1TJ7A 2PTSA 4E88A 1HY1A 4ADLA 1GK2A 1I0AA 1U0LA 2JAOA 4L6AA 1Z4IA 5M0JA 3NO9A 2VSFA 3CRW1 1JSWA 5D6BA 1Q91A 2OHYA 4C6GA 3E04A 5M0IA 3F4SA 1FURA 3CI0K 1MH9A 4BABA 5HW2A 2I7DA 3GZHA 4NFLA 1YFEA 2O7FA 1XWOA 3RRPA 3CZOA 3C8TA 4APAA 2D27A 1Z4PX
chains in the Genus database with same CATH topology
4C5SA 5EYTA 5F92A 4FFXA 2O7BA 4C5UA 2X75A 4NSLA 1GKMA 3KDZA 3NZ4A 1FUPA 1EB4A 2FUSA 2PTRA 3OCEA 2HVGA 3OCFA 3RD8A 2QVEA 3GTDA 2VD6A 4ADMA 5F91A 4V2QA 3R6QA 1DOFA 2O78A 2O7EA 1TJWA 1W27A 2RJRA 1DCNA 4BAAA 1RE5A 1U15A 2PTQA 2NYNA 4V2RA 1T6PA 1Y2MA 1B8FA 1TJUA 2J91A 2QGAB 1HY0A 1U16A 1KQ7A 3BHGA 2O6YA 1YISA 4CQ5A 3R6YA 5EYVA 2E9FA 1GK3A 1C3CA 3KDYA 2NYFA 4MX2A 1T6JA 4NLEA 1AUWA 3TV2A 4EEIA 1K7WA 4FLCA 3R6VA 1C3UA 2RJSA 3UNVA 1VDKA 1TJVA 4APBA 2YIIA 1K62A 1J3UA 4EFCA 1YFMA 2O7DA 1Q5NA 3QBPA 1FUQA 1FUOA 2PFMA 1GKJA 4C5RA 4HGVA 1TJ7A 2PTSA 1HY1A 4ADLA 1GK2A 1I0AA 3NO9A 1JSWA 5D6BA 2OHYA 4C6GA 3E04A 1FURA 4BABA 5HW2A 3GZHA 1YFEA 2O7FA 1XWOA 3RRPA 3CZOA 3C8TA 4APAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C5S A;  5EYT A;  5F92 A;  4FFX A;  2O7B A;  4C5U A;  2X75 A;  4NSL A;  1GKM A;  3KDZ A;  3NZ4 A;  1FUP A;  1EB4 A;  2FUS A;  2PTR A;  3OCE A;  2HVG A;  3OCF A;  3RD8 A;  2QVE A;  3GTD A;  2VD6 A;  4ADM A;  5F91 A;  4V2Q A;  3R6Q A;  1DOF A;  2O78 A;  2O7E A;  1TJW A;  1W27 A;  2RJR A;  1DCN A;  4BAA A;  1RE5 A;  1U15 A;  2PTQ A;  2NYN A;  4V2R A;  1T6P A;  1Y2M A;  1B8F A;  1TJU A;  2J91 A;  2QGA B;  1HY0 A;  1U16 A;  1KQ7 A;  3BHG A;  2O6Y A;  1YIS A;  4CQ5 A;  3R6Y A;  5EYV A;  2E9F A;  1GK3 A;  1C3C A;  3KDY A;  2NYF A;  4MX2 A;  1T6J A;  4NLE A;  1AUW A;  3TV2 A;  4EEI A;  1K7W A;  4FLC A;  3R6V A;  1C3U A;  2RJS A;  3UNV A;  1VDK A;  1TJV A;  4APB A;  2YII A;  1K62 A;  1J3U A;  4EFC A;  1YFM A;  2O7D A;  1Q5N A;  3QBP A;  1FUQ A;  1FUO A;  2PFM A;  1GKJ A;  4C5R A;  4HGV A;  1TJ7 A;  2PTS A;  1HY1 A;  4ADL A;  1GK2 A;  1I0A A;  3NO9 A;  1JSW A;  5D6B A;  2OHY A;  4C6G A;  3E04 A;  1FUR A;  4BAB A;  5HW2 A;  3GZH A;  1YFE A;  2O7F A;  1XWO A;  3RRP A;  3CZO A;  3C8T A;  4APA A; 
#chains in the Genus database with same CATH topology
 4C5S A;  5EYT A;  1Z4K A;  5F92 A;  1IW7 D;  3BWV A;  4FFX A;  2O7B A;  4C5U A;  2X75 A;  4NSL A;  1GKM A;  3KDZ A;  3NZ4 A;  2FEN A;  1FUP A;  3U13 A;  1EB4 A;  3F4T A;  2FEL A;  2FUS A;  2PTR A;  4YIH A;  2VL7 A;  2YV5 A;  3OCE A;  2JAU A;  2JAW A;  2HVG A;  3OCF A;  3RD8 A;  2QVE A;  3GTD A;  2VD6 A;  5H8W A;  4ADM A;  5F91 A;  4V2Q A;  4A15 A;  3R6Q A;  1XMD A;  1DOF A;  1Z4J A;  2O78 A;  2O7E A;  1TJW A;  4L6C A;  1W27 A;  2RJR A;  4YIK A;  1DCN A;  2JAR A;  4BAA A;  1RE5 A;  1U15 A;  2PTQ A;  2NYN A;  4V2R A;  1T6P A;  1Y2M A;  1B8F A;  1TJU A;  2J91 A;  2QGA B;  1HY0 A;  1U16 A;  1KQ7 A;  1XL7 A;  3BHG A;  2O6Y A;  1YIS A;  4CQ5 A;  3U19 A;  3R6Y A;  5EYV A;  2E9F A;  1Z4L A;  1GK3 A;  1C3C A;  3CRV A;  3KDY A;  2NYF A;  4MWO A;  1Q92 A;  1Z4M A;  4MX2 A;  1T6J A;  4NLE A;  3F4R A;  1AUW A;  4L57 A;  3TV2 A;  1T9H A;  1XL8 A;  1XMC A;  2RCN A;  4MUM A;  1K7W A;  4EEI A;  2D28 C;  4FLC A;  1XLY A;  3R6V A;  4IQJ M;  1C3U A;  2RJS A;  3UNV A;  1VDK A;  4WNL A;  1TJV A;  4APB A;  1Z4Q A;  2YII A;  1K62 A;  1J3U A;  4EFC A;  1YFM A;  2O7D A;  1Q5N A;  3QBP A;  1FUQ A;  1FUO A;  2PFM A;  1GKJ A;  4C5R A;  4HGV A;  1TJ7 A;  2PTS A;  4E88 A;  1HY1 A;  4ADL A;  1GK2 A;  1I0A A;  1U0L A;  2JAO A;  4L6A A;  1Z4I A;  5M0J A;  3NO9 A;  2VSF A;  3CRW 1;  1JSW A;  5D6B A;  1Q91 A;  2OHY A;  4C6G A;  3E04 A;  5M0I A;  3F4S A;  1FUR A;  3CI0 K;  1MH9 A;  4BAB A;  5HW2 A;  2I7D A;  3GZH A;  4NFL A;  1YFE A;  2O7F A;  1XWO A;  3RRP A;  3CZO A;  3C8T A;  4APA A;  2D27 A;  1Z4P X; 
#chains in the Genus database with same CATH homology
 4C5S A;  5EYT A;  5F92 A;  4FFX A;  2O7B A;  4C5U A;  2X75 A;  4NSL A;  1GKM A;  3KDZ A;  3NZ4 A;  1FUP A;  1EB4 A;  2FUS A;  2PTR A;  3OCE A;  2HVG A;  3OCF A;  3RD8 A;  2QVE A;  3GTD A;  2VD6 A;  4ADM A;  5F91 A;  4V2Q A;  3R6Q A;  1DOF A;  2O78 A;  2O7E A;  1TJW A;  1W27 A;  2RJR A;  1DCN A;  4BAA A;  1RE5 A;  1U15 A;  2PTQ A;  2NYN A;  4V2R A;  1T6P A;  1Y2M A;  1B8F A;  1TJU A;  2J91 A;  2QGA B;  1HY0 A;  1U16 A;  1KQ7 A;  3BHG A;  2O6Y A;  1YIS A;  4CQ5 A;  3R6Y A;  5EYV A;  2E9F A;  1GK3 A;  1C3C A;  3KDY A;  2NYF A;  4MX2 A;  1T6J A;  4NLE A;  1AUW A;  3TV2 A;  4EEI A;  1K7W A;  4FLC A;  3R6V A;  1C3U A;  2RJS A;  3UNV A;  1VDK A;  1TJV A;  4APB A;  2YII A;  1K62 A;  1J3U A;  4EFC A;  1YFM A;  2O7D A;  1Q5N A;  3QBP A;  1FUQ A;  1FUO A;  2PFM A;  1GKJ A;  4C5R A;  4HGV A;  1TJ7 A;  2PTS A;  1HY1 A;  4ADL A;  1GK2 A;  1I0A A;  3NO9 A;  1JSW A;  5D6B A;  2OHY A;  4C6G A;  3E04 A;  1FUR A;  4BAB A;  5HW2 A;  3GZH A;  1YFE A;  2O7F A;  1XWO A;  3RRP A;  3CZO A;  3C8T A;  4APA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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