1YH8A

Crystal structure of aquifex aeolicus lpxc deacetylase complexed with palmitate
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine Deacetylase Functions through a General Acid-Base Catalyst Pair Mechanism
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 86
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2005-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1yh8A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1yh8A02
3PS2A 4LCHA 3U1YA 2IERA 3P76A 5DROA 3PS1A 3P3CA 4LCGA 5DRPA 4MQYA 4U3DA 5DRRA 4IS9A 2GO4A 1YH8A 3UHMA 4FW6A 4OKGA 3P3EA 2GO3A 4J3DA 1XXEA 3PS3A 4MDTA 2VESA 4OZEA 1P42A 4FW7A 4FW5A 2O3ZA 5DRQA 4FW3A 4U3BA 4LCFA 1YHCA 2JT2A 4ISAA 2J65A 3NZKA 4FW4A 2IESA 3P3GA
chains in the Genus database with same CATH superfamily
4GKJE 3LTOA 4UT4A 4LFCI 1IBLE 5C0XA 4BA2B 5DRRA 2PNLA 5GMDA 5IWAI 5FLXC 4LFCE 2UUCI 5K36E 4LF4I 1Z0EA 5IWAE 2X7IA 4DR3I 2CVEA 2BA0G 2UUCE 2PO0A 3J7AG 1XNQE 2NPFA 4LF4E 3PYDA 2AJ4A 2J65A 1QZRA 1R6MA 4HACA 4IZKA 4R1FA 3J81C 1FKAE 2JE6B 2PNZB 1PKPA 2O1TA 2HKJA 2BA1D 3B4TA 2BR2A 4FWDA 3V5RA 1Z0GA 4OKGA 4MU0A 4I3HA 4JI2I 3M6AA 3L7ZB 4IZJB 3ZKDA 4JI2E 1HK7A 3WU3A 1FWLA 1UDOA 5JEAD 4DV6E 4GQUA 2WNRA 4P7AA 4N3OA 5LMUE 4ED4A 2XEXA 4X66E 3Q1QA 1ZM2A 5DRPA 4MYUA 2C38A 4DV4I 1OYPA 2ZITA 2HK2A 2R3VA 4LF7I 4OO1A 3UHMA 2JEAB 4DV4E 4LF5I 4LF7E 4AIDA 3CDJA 1FNMA 4AIMA 2BA1G 4LF5E 2BV3A 4B3ME 1N34I 1D6TA 1PVGA 2C37B 1EI1A 1MG7A 5JEAA 3OTOE 1Z59A 1HNZI 1N34E 5K36F 2WW4A 4FW9A 3PRYA 2E5LI 1Z0VA 5K36C 1S4EA 1HNZE 1XMQI 1XNRI 2E5LE 1IBMI 2PO2B 5DNXA 1H7SA 2BM0A 3WU6A 1XMQE 1XNRE 1HNXI 4DR5E 4B3RI 2A2CA 4ZVIA 1IBME 4DPTA 4WUDA 2IOPA 4IFDF 2IESA 1WUUA 3P3GA 4JI8I 4LCHA 1HNXE 3J80C 4B3RE 4DPXA 2Z5CB 2UXCI 1K47A 4M1KA 1IBKI 4U3DA 3JAMQ 2UXCE 1N33E 4FW6A 3P3EA 1IBKE 4JV5I 1FI4A 4HY1A 4Z7CA 1OYRA 4HYMA 4IZJD 2O3ZA 4FW3A 4U3BA 1UEKA 5A2QQ 4FW4A 1IBLI 1KIJA 1UDQA 4OX9I 3HULA 4FN5A 2A2DA 3PYGA 1H74A 1J5EI 3HJCA 4HXZA 4OX9E 4DV7I 1RHYA 2PNZA 1J5EE 2GO4A 4IFDB 4DV7E 3WU4A 1XNQI 1XXEA 2JEBB 2Z5BA 3B82A 4IZJA 2CZ9A 2CGEA 2R42A 1RREA 3NZKA 5EL9A 4AM3A 4LFBI 4B3SI 4KHPI 4JYAI 4USMA 4DR7I 3T1YE 4LFBE 2V2QA 4B3SE 4KHPE 1Z5CA 3GCMA 4DV1I 4IFDE 1B62A 4B3TI 4JYAE 1UDSA 3F0NA 4DR7E 4DV1E 3GONA 4B3TE 4LFAI 1Z0WA 3ZKBA 4FW5A 3ZZTA 4DUZI 4DR4I 4JI7I 4DV6I 3Q6MA 4LFAE 5LMUI 4X66I 2NN6F 1E3PA 4DUZE 1NHIA 2OI2A 4JI7E 4DR4E 5DNLA 3DD6A 1Z5BA 5EKWA 2C39B 3LNUA 4FWHA 2VF3A 1UDNA 1N32I 3QT7A 1Y60A 4MU4A 1EA6A 1MU5A 1N32E 5FLXQ 2PO0B 4B3MI 4FW7A 1USUA 5K36D 3OTOI 2UXBI 4PRXA 2LJPA 3U1KA 4HACB 2Q2EB 1KVKA 1B63A 2UXBE 2VQFI 1U2RA 5BR8I 4YHHI 1N0UA 1ZXNA 4MU1A 1H72C 4USKA 1FJGI 4MQYA 2BR2B 2GQ0A 4PRVA 4JI6I 2VQFE 4LPFA 1ZM4A 5BR8E 4YHHE 3J81Q 1FJGE 4IFDD 2NN6B 4DR5I 4DR1I 2PO1A 3V2UC 4JI6E 2IOQA 5K36A 1FWKA 1USVA 4DV5I 4DR1E 4ISAA 2WNRB 1VISA 4DV5E 4IFDC 1N33I 2C38B 4DV3I 4BA2A 4DPYA 4OO1B 4IS9A 4JI4I 2NN6E 4DV2I 1R6LA 4IFDA 4DV3E 2J7KA 4JI4E 2VESA 1ZM3A 2JEBA 4DV2E 2HHHI 1OYSA 2V2ZA 4NBQA 4Z7YA 4DUYI 4K0KI 2HHHE 2Z5EA 4YY3I 4DUYE 4LOMA 5L3JA 4LF6I 4K0KE 2HK3A 2X36A 4OO1E 1Y4UA 4LCGA 2UUAE 4YY3E 1H7UA 2JE6A 4LF6E 4LF8I 2HFUA 2ZBKB 1N0VC 1I94E 1DARA 4MU3A 5ELWA 5C0XF 3WU5A 3ZZ0A 3P06A 1XMOI 4LF8E 4DPUA 4OZEA 1HR0I 1N36I 4X62I 3L7ZA 4LCFA 4JI0E 2UU9E 1XMOE 1HR0E 4PU9A 1N36E 4X62E 3T1YI 4JG4A 1NHHA 4MYTA 2C39A 4LF9I 3J80Q 2O1VA 1KTVA 4AQYI 1Y5YA 4FWGA 3B78A 3ZZUA 1Z0BA 4LF9E 4J3DA 3M7ND 2NN6D 2JEAA 2WP8B 4BA1B 4AQYE 4WUBA 2DEIA 1Y4SA 4JI1I 2JT2A 4DR3E 5GMEA 4X64I 3QT8A 4JI3I 2DEJA 3GLLA 3ZM7A 4DPWA 2V34A 3D4JA 3U1YA 2C37A 4QNJA 4JI1E 2IERA 3P76A 5DROA 5C0XB 4X64E 2HKEA 1ZXMA 4JI3E 2NN6C 3P3CA 2VQEI 4DR6I 4OO1D 2O1WA 5LL6R 2ZM6I 4KQVA 2VQEE 2V2VA 2Z5BB 4DR6E 3PS3A 2NN6A 3J7AM 1KKHA 2PO2A 2ZM6E 5IT9C 1YHCA 4EMDA 4OO1F 4DU8A 1HNWI 2CG9A 1XHKA 1NZ0A 4DR2I 1RR9A 5C0XE 4OO1C 4IZKB 1E3HA 3M7NG 3PYEA 3JAMC 4UTGA 1HNWE 1ELOA 2Z5CA 1PIEA 3M85D 4DR2E 1Z0TA 2V8PA 4DU7A 4DXLA 2E1RA 5JEAF 3K85A 1YH8A 1VI7A 1BKNA 5A2QC 5JEAC 3T1HI 5FWKA 4P52A 1Y6ZA 1OJ4A 3LPSA 2GS8A 3QT6A 3HKMA 5DRQA 4XTJA 3T1HE 3PYFA 4GKKI 3K17A 3PS1A 4QNKA 4DV0I 4NXMI 2EFGA 3KRNA 4GKKE 5LMNI 3B8HA 4X65I 4DV0E 4NXME 1H73A 5LMNE 2UXDI 1Z5AA 4MDTA 4X65E 2O1UA 1P42A 1Z0CA 3M85G 2AE8A 2UUBI 1ZM9A 2HFSA 2UXDE 3K1JA 1MX0A 2PNMA 4URLA 4NXNI 4WUCA 1A6FA 5JEAB 2UUBE 3PS2A 4JI5I 5IT9Q 1S16A 2UUAI 3Q6NA 5C0XD 2BA0D 4JI8E 4NXNE 3CWVA 4JI5E 1I94I 3GMEA 3H1CA 2PO1B 2GO3A 4RPFA 2F4VI 4JI0I 2UU9I 2BM1A 2WP8A 5K36B 4BA1A 3CDIA 4JV5E 3H4LA 3QT5A 5C0XC 4GKJI 1NHJA 5JEAE 2F4VE 2F1DA
chains in the Genus database with same CATH topology
3PS2A 4LCHA 3U1YA 2IERA 3P76A 5DROA 3PS1A 3P3CA 4LCGA 5DRPA 4MQYA 4U3DA 5DRRA 4IS9A 2GO4A 1YH8A 3UHMA 4FW6A 4OKGA 3P3EA 2GO3A 4J3DA 1XXEA 3PS3A 4MDTA 2VESA 4OZEA 1P42A 4FW7A 4FW5A 2O3ZA 5DRQA 4FW3A 4U3BA 4LCFA 1YHCA 2JT2A 4ISAA 2J65A 3NZKA 4FW4A 2IESA 3P3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS2 A;  4LCH A;  3U1Y A;  2IER A;  3P76 A;  5DRO A;  3PS1 A;  3P3C A;  4LCG A;  5DRP A;  4MQY A;  4U3D A;  5DRR A;  4IS9 A;  2GO4 A;  1YH8 A;  3UHM A;  4FW6 A;  4OKG A;  3P3E A;  2GO3 A;  4J3D A;  1XXE A;  3PS3 A;  4MDT A;  2VES A;  4OZE A;  1P42 A;  4FW7 A;  4FW5 A;  2O3Z A;  5DRQ A;  4FW3 A;  4U3B A;  4LCF A;  1YHC A;  2JT2 A;  4ISA A;  2J65 A;  3NZK A;  4FW4 A;  2IES A;  3P3G A; 
#chains in the Genus database with same CATH topology
 4GKJ E;  3LTO A;  4UT4 A;  4LFC I;  1IBL E;  5C0X A;  4BA2 B;  5DRR A;  2PNL A;  5GMD A;  5IWA I;  5FLX C;  4LFC E;  2UUC I;  5K36 E;  4LF4 I;  1Z0E A;  5IWA E;  2X7I A;  4DR3 I;  2CVE A;  2BA0 G;  2UUC E;  2PO0 A;  3J7A G;  1XNQ E;  2NPF A;  4LF4 E;  3PYD A;  2AJ4 A;  2J65 A;  1QZR A;  1R6M A;  4HAC A;  4IZK A;  4R1F A;  3J81 C;  1FKA E;  2JE6 B;  2PNZ B;  1PKP A;  2O1T A;  2HKJ A;  2BA1 D;  3B4T A;  2BR2 A;  4FWD A;  3V5R A;  1Z0G A;  4OKG A;  4MU0 A;  4I3H A;  4JI2 I;  3M6A A;  3L7Z B;  4IZJ B;  3ZKD A;  4JI2 E;  1HK7 A;  3WU3 A;  1FWL A;  1UDO A;  5JEA D;  4DV6 E;  4GQU A;  2WNR A;  4P7A A;  4N3O A;  5LMU E;  4ED4 A;  2XEX A;  4X66 E;  3Q1Q A;  1ZM2 A;  5DRP A;  4MYU A;  2C38 A;  4DV4 I;  1OYP A;  2ZIT A;  2HK2 A;  2R3V A;  4LF7 I;  4OO1 A;  3UHM A;  2JEA B;  4DV4 E;  4LF5 I;  4LF7 E;  4AID A;  3CDJ A;  1FNM A;  4AIM A;  2BA1 G;  4LF5 E;  2BV3 A;  4B3M E;  1N34 I;  1D6T A;  1PVG A;  2C37 B;  1EI1 A;  1MG7 A;  5JEA A;  3OTO E;  1Z59 A;  1HNZ I;  1N34 E;  5K36 F;  2WW4 A;  4FW9 A;  3PRY A;  2E5L I;  1Z0V A;  5K36 C;  1S4E A;  1HNZ E;  1XMQ I;  1XNR I;  2E5L E;  1IBM I;  2PO2 B;  5DNX A;  1H7S A;  2BM0 A;  3WU6 A;  1XMQ E;  1XNR E;  1HNX I;  4DR5 E;  4B3R I;  2A2C A;  4ZVI A;  1IBM E;  4DPT A;  4WUD A;  2IOP A;  4IFD F;  2IES A;  1WUU A;  3P3G A;  4JI8 I;  4LCH A;  1HNX E;  3J80 C;  4B3R E;  4DPX A;  2Z5C B;  2UXC I;  1K47 A;  4M1K A;  1IBK I;  4U3D A;  3JAM Q;  2UXC E;  1N33 E;  4FW6 A;  3P3E A;  1IBK E;  4JV5 I;  1FI4 A;  4HY1 A;  4Z7C A;  1OYR A;  4HYM A;  4IZJ D;  2O3Z A;  4FW3 A;  4U3B A;  1UEK A;  5A2Q Q;  4FW4 A;  1IBL I;  1KIJ A;  1UDQ A;  4OX9 I;  3HUL A;  4FN5 A;  2A2D A;  3PYG A;  1H74 A;  1J5E I;  3HJC A;  4HXZ A;  4OX9 E;  4DV7 I;  1RHY A;  2PNZ A;  1J5E E;  2GO4 A;  4IFD B;  4DV7 E;  3WU4 A;  1XNQ I;  1XXE A;  2JEB B;  2Z5B A;  3B82 A;  4IZJ A;  2CZ9 A;  2CGE A;  2R42 A;  1RRE A;  3NZK A;  5EL9 A;  4AM3 A;  4LFB I;  4B3S I;  4KHP I;  4JYA I;  4USM A;  4DR7 I;  3T1Y E;  4LFB E;  2V2Q A;  4B3S E;  4KHP E;  1Z5C A;  3GCM A;  4DV1 I;  4IFD E;  1B62 A;  4B3T I;  4JYA E;  1UDS A;  3F0N A;  4DR7 E;  4DV1 E;  3GON A;  4B3T E;  4LFA I;  1Z0W A;  3ZKB A;  4FW5 A;  3ZZT A;  4DUZ I;  4DR4 I;  4JI7 I;  4DV6 I;  3Q6M A;  4LFA E;  5LMU I;  4X66 I;  2NN6 F;  1E3P A;  4DUZ E;  1NHI A;  2OI2 A;  4JI7 E;  4DR4 E;  5DNL A;  3DD6 A;  1Z5B A;  5EKW A;  2C39 B;  3LNU A;  4FWH A;  2VF3 A;  1UDN A;  1N32 I;  3QT7 A;  1Y60 A;  4MU4 A;  1EA6 A;  1MU5 A;  1N32 E;  5FLX Q;  2PO0 B;  4B3M I;  4FW7 A;  1USU A;  5K36 D;  3OTO I;  2UXB I;  4PRX A;  2LJP A;  3U1K A;  4HAC B;  2Q2E B;  1KVK A;  1B63 A;  2UXB E;  2VQF I;  1U2R A;  5BR8 I;  4YHH I;  1N0U A;  1ZXN A;  4MU1 A;  1H72 C;  4USK A;  1FJG I;  4MQY A;  2BR2 B;  2GQ0 A;  4PRV A;  4JI6 I;  2VQF E;  4LPF A;  1ZM4 A;  5BR8 E;  4YHH E;  3J81 Q;  1FJG E;  4IFD D;  2NN6 B;  4DR5 I;  4DR1 I;  2PO1 A;  3V2U C;  4JI6 E;  2IOQ A;  5K36 A;  1FWK A;  1USV A;  4DV5 I;  4DR1 E;  4ISA A;  2WNR B;  1VIS A;  4DV5 E;  4IFD C;  1N33 I;  2C38 B;  4DV3 I;  4BA2 A;  4DPY A;  4OO1 B;  4IS9 A;  4JI4 I;  2NN6 E;  4DV2 I;  1R6L A;  4IFD A;  4DV3 E;  2J7K A;  4JI4 E;  2VES A;  1ZM3 A;  2JEB A;  4DV2 E;  2HHH I;  1OYS A;  2V2Z A;  4NBQ A;  4Z7Y A;  4DUY I;  4K0K I;  2HHH E;  2Z5E A;  4YY3 I;  4DUY E;  4LOM A;  5L3J A;  4LF6 I;  4K0K E;  2HK3 A;  2X36 A;  4OO1 E;  1Y4U A;  4LCG A;  2UUA E;  4YY3 E;  1H7U A;  2JE6 A;  4LF6 E;  4LF8 I;  2HFU A;  2ZBK B;  1N0V C;  1I94 E;  1DAR A;  4MU3 A;  5ELW A;  5C0X F;  3WU5 A;  3ZZ0 A;  3P06 A;  1XMO I;  4LF8 E;  4DPU A;  4OZE A;  1HR0 I;  1N36 I;  4X62 I;  3L7Z A;  4LCF A;  4JI0 E;  2UU9 E;  1XMO E;  1HR0 E;  4PU9 A;  1N36 E;  4X62 E;  3T1Y I;  4JG4 A;  1NHH A;  4MYT A;  2C39 A;  4LF9 I;  3J80 Q;  2O1V A;  1KTV A;  4AQY I;  1Y5Y A;  4FWG A;  3B78 A;  3ZZU A;  1Z0B A;  4LF9 E;  4J3D A;  3M7N D;  2NN6 D;  2JEA A;  2WP8 B;  4BA1 B;  4AQY E;  4WUB A;  2DEI A;  1Y4S A;  4JI1 I;  2JT2 A;  4DR3 E;  5GME A;  4X64 I;  3QT8 A;  4JI3 I;  2DEJ A;  3GLL A;  3ZM7 A;  4DPW A;  2V34 A;  3D4J A;  3U1Y A;  2C37 A;  4QNJ A;  4JI1 E;  2IER A;  3P76 A;  5DRO A;  5C0X B;  4X64 E;  2HKE A;  1ZXM A;  4JI3 E;  2NN6 C;  3P3C A;  2VQE I;  4DR6 I;  4OO1 D;  2O1W A;  5LL6 R;  2ZM6 I;  4KQV A;  2VQE E;  2V2V A;  2Z5B B;  4DR6 E;  3PS3 A;  2NN6 A;  3J7A M;  1KKH A;  2PO2 A;  2ZM6 E;  5IT9 C;  1YHC A;  4EMD A;  4OO1 F;  4DU8 A;  1HNW I;  2CG9 A;  1XHK A;  1NZ0 A;  4DR2 I;  1RR9 A;  5C0X E;  4OO1 C;  4IZK B;  1E3H A;  3M7N G;  3PYE A;  3JAM C;  4UTG A;  1HNW E;  1ELO A;  2Z5C A;  1PIE A;  3M85 D;  4DR2 E;  1Z0T A;  2V8P A;  4DU7 A;  4DXL A;  2E1R A;  5JEA F;  3K85 A;  1YH8 A;  1VI7 A;  1BKN A;  5A2Q C;  5JEA C;  3T1H I;  5FWK A;  4P52 A;  1Y6Z A;  1OJ4 A;  3LPS A;  2GS8 A;  3QT6 A;  3HKM A;  5DRQ A;  4XTJ A;  3T1H E;  3PYF A;  4GKK I;  3K17 A;  3PS1 A;  4QNK A;  4DV0 I;  4NXM I;  2EFG A;  3KRN A;  4GKK E;  5LMN I;  3B8H A;  4X65 I;  4DV0 E;  4NXM E;  1H73 A;  5LMN E;  2UXD I;  1Z5A A;  4MDT A;  4X65 E;  2O1U A;  1P42 A;  1Z0C A;  3M85 G;  2AE8 A;  2UUB I;  1ZM9 A;  2HFS A;  2UXD E;  3K1J A;  1MX0 A;  2PNM A;  4URL A;  4NXN I;  4WUC A;  1A6F A;  5JEA B;  2UUB E;  3PS2 A;  4JI5 I;  5IT9 Q;  1S16 A;  2UUA I;  3Q6N A;  5C0X D;  2BA0 D;  4JI8 E;  4NXN E;  3CWV A;  4JI5 E;  1I94 I;  3GME A;  3H1C A;  2PO1 B;  2GO3 A;  4RPF A;  2F4V I;  4JI0 I;  2UU9 I;  2BM1 A;  2WP8 A;  5K36 B;  4BA1 A;  3CDI A;  4JV5 E;  3H4L A;  3QT5 A;  5C0X C;  4GKJ I;  1NHJ A;  5JEA E;  2F4V E;  2F1D A; 
#chains in the Genus database with same CATH homology
 3PS2 A;  4LCH A;  3U1Y A;  2IER A;  3P76 A;  5DRO A;  3PS1 A;  3P3C A;  4LCG A;  5DRP A;  4MQY A;  4U3D A;  5DRR A;  4IS9 A;  2GO4 A;  1YH8 A;  3UHM A;  4FW6 A;  4OKG A;  3P3E A;  2GO3 A;  4J3D A;  1XXE A;  3PS3 A;  4MDT A;  2VES A;  4OZE A;  1P42 A;  4FW7 A;  4FW5 A;  2O3Z A;  5DRQ A;  4FW3 A;  4U3B A;  4LCF A;  1YHC A;  2JT2 A;  4ISA A;  2J65 A;  3NZK A;  4FW4 A;  2IES A;  3P3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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