1YH8A

Crystal structure of aquifex aeolicus lpxc deacetylase complexed with palmitate
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine Deacetylase Functions through a General Acid-Base Catalyst Pair Mechanism
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 86
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2005-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1yh8A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1yh8A02
4LCHA 4FW5A 3P3GA 4U3DA 3P3EA 2JT2A 4OZEA 2GO4A 1P42A 1YHCA 5DRRA 3NZKA 2IERA 4MDTA 4U3BA 5DROA 4ISAA 5DRQA 4IS9A 4J3DA 3PS2A 2O3ZA 2GO3A 4LCGA 4FW6A 3PS3A 3P3CA 4FW3A 3U1YA 4FW7A 4LCFA 4MQYA 3PS1A 5DRPA 1XXEA 4FW4A 1YH8A 2J65A 3UHMA 2VESA 2IESA 4OKGA 3P76A
chains in the Genus database with same CATH superfamily
1Z0GA 4DV4I 2PO0B 4X64I 4DV7I 1N34I 5FLXC 4B3TI 4ISAA 4DR3E 1NHHA 2V2VA 1J5EE 4B3SI 1Z0BA 2EFGA 4FWGA 2UU9E 2JEAA 2Z5CA 4FW6A 1UDNA 3M7ND 2J7KA 5LMNI 1ZM2A 2ZITA 1XXEA 3CDIA 5L3JA 1HNZE 3GMEA 4LF4I 2DEIA 1I94I 1Z0WA 1Y6ZA 2A2DA 1YHCA 2GQ0A 4YY3I 2IERA 2HK3A 1EA6A 3KRNA 4AQYI 1N0UA 5K36A 2O1VA 3LTOA 1XNRI 1PKPA 5C0XD 1XMQI 4LF8E 2OI2A 4P52A 4X65E 4DV0E 3P3CA 4ED4A 3PYGA 3GLLA 4JI3I 4MYUA 4IZJA 2JEBB 2IESA 4YHHI 2HHHE 2WNRA 1UDSA 5JEAB 1FI4A 4OX9I 4FW5A 1KVKA 1N33I 4IFDA 4NXNI 4JI2E 5EL9A 1UDQA 2X7IA 3HJCA 2V34A 1Z0EA 1HNWE 2JEAB 1FWKA 1Z0CA 4JI1I 4RPFA 3QT7A 4P7AA 3D4JA 5C0XE 4B3ME 4LFCE 4IZJB 1NHJA 3V5RA 1XMQE 4LF8I 4JI7I 4GKKE 4JI0I 3GCMA 2F4VE 1PVGA 1N36I 5DNXA 4K0KI 4IZKB 2UXBE 1S4EA 4DR5I 1XNQE 4DR5E 1ZM4A 4JI6I 4LOMA 4IZKA 5DRPA 2LJPA 3GONA 4MU3A 4JI0E 2VESA 1HNXE 2HKEA 3M6AA 5LMNE 3J7AG 1H72C 4URLA 2X36A 2IOPA 1XNRE 3J80Q 4AIMA 1USUA 1Z0VA 2E5LE 4DV4E 1WUUA 2JEBA 1HNXI 5C0XF 1IBMI 3LNUA 4GQUA 5JEAC 3PS1A 4DXLA 4DV3I 4KHPI 1I94E 1A6FA 2VF3A 3CDJA 2Z5BB 3ZKDA 4OX9E 2V2ZA 4DUZE 2PNZA 2PNMA 4QNJA 4U3DA 5DNLA 2C37B 1B63A 1N36E 1OJ4A 2PO1A 3L7ZB 4MDTA 4DR6E 3LPSA 4IS9A 4LFAI 3PS2A 4DV5E 4OO1B 2C39B 4Z7CA 1FKAE 4DR3I 2NN6B 4DPUA 3WU4A 5GMEA 5BR8I 2C39A 2BM1A 4HACB 2NPFA 5K36F 1HNWI 1H73A 2BA0D 2NN6F 3PYFA 1H74A 1U2RA 4JV5E 4OZEA 4DV6I 1FJGE 1OYRA 4LF9E 2CZ9A 3NZKA 4LF6I 5C0XA 4NXMI 2UXCE 4JI8I 4PRXA 4YHHE 4DR2I 4IFDC 4MYTA 2CGEA 5LMUI 4B3TE 1Y4UA 3B8HA 4HYMA 4JYAE 4DV1E 3T1YE 4LCHA 3P3GA 1RREA 5DROA 1Z5BA 2R42A 5K36B 3J7AM 2HK2A 4HXZA 2UXBI 4OO1A 3F0NA 1OYPA 4DR4E 4KQVA 2VQFE 4LPFA 2F4VI 2WNRB 4AM3A 1VISA 4X66E 2R3VA 1Y60A 4B3MI 4I3HA 4OKGA 1D6TA 3M85G 4USMA 4JI8E 3QT5A 3J80C 4DUZI 3P3EA 4FW9A 2C38A 3T1HE 2GO4A 2NN6C 4UT4A 2ZM6I 2Z5CB 3HKMA 4BA2B 2CVEA 2O1TA 3PYDA 4MU4A 4M1KA 4LF7E 1B62A 3PYEA 3M85D 4HACA 4DV2E 4OO1D 3V2UC 5A2QQ 2HFUA 4JYAI 1H7UA 2Q2EB 4GKJE 1Z0TA 3Q6NA 4DV0I 2XEXA 2BA1D 1E3HA 4DR7E 4DR7I 1NZ0A 3ZZ0A 5JEAA 4JI4I 1HR0I 1MX0A 2PO1B 1UEKA 2C37A 4X65I 4BA2A 2JE6A 1K47A 2HKJA 4NXME 2VQEE 5ELWA 2UUAI 1MG7A 1IBKI 3K1JA 4LF9I 1N32E 3QT8A 4X62E 4DV3E 4KHPE 1ZM3A 2O1UA 2NN6A 4FW7A 4LCFA 4MQYA 3WU6A 3B82A 2PNLA 1IBKE 3PRYA 4DV1I 3T1YI 1J5EI 4B3SE 2V2QA 4B3RE 3ZKBA 2BA0G 3K85A 4IZJD 4JI5I 3J81Q 4LFAE 2UU9I 2WW4A 4DR6I 3ZM7A 3OTOI 1Y4SA 5JEAF 2UUBE 4IFDD 1KIJA 4LF6E 2UXDE 2IOQA 1BKNA 1HK7A 4DUYI 2J65A 5FLXQ 2Z5BA 2PO0A 2C38B 4ZVIA 4PU9A 2UXDI 1N32I 1RHYA 4OO1E 3QT6A 3H4LA 1IBME 3B4TA 4DPXA 4WUCA 5BR8E 4DPYA 4NBQA 1ZXMA 4EMDA 2E5LI 4JI3E 4DPTA 2JE6B 1UDOA 1DARA 4JI5E 1USVA 5JEAD 4LFBE 2AE8A 3PS3A 1FNMA 3ZZUA 4FW3A 5JEAE 4AQYE 2BR2A 1N0VC 2F1DA 4LF5E 3B78A 4N3OA 1H7SA 4BA1B 2AJ4A 4DV2I 5C0XB 4DU7A 4JG4A 2PO2A 2NN6D 2JT2A 3Q1QA 4YY3E 1P42A 4DR1E 2NN6E 1RR9A 1XNQI 5DRQA 2UUAE 3L7ZA 2VQEI 4IFDF 3T1HI 3DD6A 2UUCE 1ZXNA 1E3PA 4LFBI 5LMUE 3OTOE 3J81C 1XMOI 4FW4A 1Y5YA 4HY1A 1VI7A 2BV3A 3JAMC 4OO1F 2O1WA 2UXCI 4GKJI 4IFDB 2DEJA 5IT9C 5LL6R 4AIDA 4DR4I 4JI1E 5DRRA 1OYSA 2A2CA 4DPWA 1NHIA 2BA1G 2PNZB 3H1CA 5FWKA 4R1FA 2WP8B 1Z59A 5IWAI 5IWAE 4K0KE 4FN5A 4NXNE 1KKHA 1Z5CA 1R6MA 2HFSA 3U1KA 1KTVA 2WP8A 4JI7E 4GKKI 3HULA 2BM0A 5K36D 2UUBI 4USKA 3P76A 4X66I 5K36E 4Z7YA 2V8PA 4DU8A 2E1RA 2VQFI 4FWHA 1XHKA 1ELOA 1PIEA 4XTJA 1XMOE 4PRVA 4B3RI 1Z5AA 5EKWA 2GS8A 2ZBKB 2PO2B 4J3DA 5A2QC 2O3ZA 2UUCI 3P06A 4JV5I 2GO3A 4LCGA 4FWDA 4QNKA 4X62I 3CWVA 4LF7I 2BR2B 1IBLE 3U1YA 4DR1I 5C0XC 2CG9A 4MU1A 4LF5I 2ZM6E 1YH8A 1N33E 1FWLA 3UHMA 4UTGA 4WUDA 2HHHI 1HNZI 4LF4E 3ZZTA 1HR0E 4OO1C 2Z5EA 1ZM9A 4DV5I 4DR2E 3K17A 1S16A 4U3BA 3WU5A 4JI4E 1EI1A 5IT9Q 3WU3A 4LFCI 3JAMQ 4X64E 4DV7E 4MU0A 1N34E 4WUBA 4IFDE 3Q6MA 4JI6E 4DV6E 1FJGI 1R6LA 5GMDA 1IBLI 4DUYE 4JI2I 1QZRA 1MU5A 4BA1A 3M7NG 5K36C
chains in the Genus database with same CATH topology
4LCHA 4FW5A 3P3GA 4U3DA 3P3EA 2JT2A 4OZEA 2GO4A 1P42A 1YHCA 5DRRA 3NZKA 2IERA 4MDTA 4U3BA 5DROA 4ISAA 5DRQA 4IS9A 4J3DA 3PS2A 2O3ZA 2GO3A 4LCGA 4FW6A 3PS3A 3P3CA 4FW3A 3U1YA 4FW7A 4LCFA 4MQYA 3PS1A 5DRPA 1XXEA 4FW4A 1YH8A 2J65A 3UHMA 2VESA 2IESA 4OKGA 3P76A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCH A;  4FW5 A;  3P3G A;  4U3D A;  3P3E A;  2JT2 A;  4OZE A;  2GO4 A;  1P42 A;  1YHC A;  5DRR A;  3NZK A;  2IER A;  4MDT A;  4U3B A;  5DRO A;  4ISA A;  5DRQ A;  4IS9 A;  4J3D A;  3PS2 A;  2O3Z A;  2GO3 A;  4LCG A;  4FW6 A;  3PS3 A;  3P3C A;  4FW3 A;  3U1Y A;  4FW7 A;  4LCF A;  4MQY A;  3PS1 A;  5DRP A;  1XXE A;  4FW4 A;  1YH8 A;  2J65 A;  3UHM A;  2VES A;  2IES A;  4OKG A;  3P76 A; 
#chains in the Genus database with same CATH topology
 1Z0G A;  4DV4 I;  2PO0 B;  4X64 I;  4DV7 I;  1N34 I;  5FLX C;  4B3T I;  4ISA A;  4DR3 E;  1NHH A;  2V2V A;  1J5E E;  4B3S I;  1Z0B A;  2EFG A;  4FWG A;  2UU9 E;  2JEA A;  2Z5C A;  4FW6 A;  1UDN A;  3M7N D;  2J7K A;  5LMN I;  1ZM2 A;  2ZIT A;  1XXE A;  3CDI A;  5L3J A;  1HNZ E;  3GME A;  4LF4 I;  2DEI A;  1I94 I;  1Z0W A;  1Y6Z A;  2A2D A;  1YHC A;  2GQ0 A;  4YY3 I;  2IER A;  2HK3 A;  1EA6 A;  3KRN A;  4AQY I;  1N0U A;  5K36 A;  2O1V A;  3LTO A;  1XNR I;  1PKP A;  5C0X D;  1XMQ I;  4LF8 E;  2OI2 A;  4P52 A;  4X65 E;  4DV0 E;  3P3C A;  4ED4 A;  3PYG A;  3GLL A;  4JI3 I;  4MYU A;  4IZJ A;  2JEB B;  2IES A;  4YHH I;  2HHH E;  2WNR A;  1UDS A;  5JEA B;  1FI4 A;  4OX9 I;  4FW5 A;  1KVK A;  1N33 I;  4IFD A;  4NXN I;  4JI2 E;  5EL9 A;  1UDQ A;  2X7I A;  3HJC A;  2V34 A;  1Z0E A;  1HNW E;  2JEA B;  1FWK A;  1Z0C A;  4JI1 I;  4RPF A;  3QT7 A;  4P7A A;  3D4J A;  5C0X E;  4B3M E;  4LFC E;  4IZJ B;  1NHJ A;  3V5R A;  1XMQ E;  4LF8 I;  4JI7 I;  4GKK E;  4JI0 I;  3GCM A;  2F4V E;  1PVG A;  1N36 I;  5DNX A;  4K0K I;  4IZK B;  2UXB E;  1S4E A;  4DR5 I;  1XNQ E;  4DR5 E;  1ZM4 A;  4JI6 I;  4LOM A;  4IZK A;  5DRP A;  2LJP A;  3GON A;  4MU3 A;  4JI0 E;  2VES A;  1HNX E;  2HKE A;  3M6A A;  5LMN E;  3J7A G;  1H72 C;  4URL A;  2X36 A;  2IOP A;  1XNR E;  3J80 Q;  4AIM A;  1USU A;  1Z0V A;  2E5L E;  4DV4 E;  1WUU A;  2JEB A;  1HNX I;  5C0X F;  1IBM I;  3LNU A;  4GQU A;  5JEA C;  3PS1 A;  4DXL A;  4DV3 I;  4KHP I;  1I94 E;  1A6F A;  2VF3 A;  3CDJ A;  2Z5B B;  3ZKD A;  4OX9 E;  2V2Z A;  4DUZ E;  2PNZ A;  2PNM A;  4QNJ A;  4U3D A;  5DNL A;  2C37 B;  1B63 A;  1N36 E;  1OJ4 A;  2PO1 A;  3L7Z B;  4MDT A;  4DR6 E;  3LPS A;  4IS9 A;  4LFA I;  3PS2 A;  4DV5 E;  4OO1 B;  2C39 B;  4Z7C A;  1FKA E;  4DR3 I;  2NN6 B;  4DPU A;  3WU4 A;  5GME A;  5BR8 I;  2C39 A;  2BM1 A;  4HAC B;  2NPF A;  5K36 F;  1HNW I;  1H73 A;  2BA0 D;  2NN6 F;  3PYF A;  1H74 A;  1U2R A;  4JV5 E;  4OZE A;  4DV6 I;  1FJG E;  1OYR A;  4LF9 E;  2CZ9 A;  3NZK A;  4LF6 I;  5C0X A;  4NXM I;  2UXC E;  4JI8 I;  4PRX A;  4YHH E;  4DR2 I;  4IFD C;  4MYT A;  2CGE A;  5LMU I;  4B3T E;  1Y4U A;  3B8H A;  4HYM A;  4JYA E;  4DV1 E;  3T1Y E;  4LCH A;  3P3G A;  1RRE A;  5DRO A;  1Z5B A;  2R42 A;  5K36 B;  3J7A M;  2HK2 A;  4HXZ A;  2UXB I;  4OO1 A;  3F0N A;  1OYP A;  4DR4 E;  4KQV A;  2VQF E;  4LPF A;  2F4V I;  2WNR B;  4AM3 A;  1VIS A;  4X66 E;  2R3V A;  1Y60 A;  4B3M I;  4I3H A;  4OKG A;  1D6T A;  3M85 G;  4USM A;  4JI8 E;  3QT5 A;  3J80 C;  4DUZ I;  3P3E A;  4FW9 A;  2C38 A;  3T1H E;  2GO4 A;  2NN6 C;  4UT4 A;  2ZM6 I;  2Z5C B;  3HKM A;  4BA2 B;  2CVE A;  2O1T A;  3PYD A;  4MU4 A;  4M1K A;  4LF7 E;  1B62 A;  3PYE A;  3M85 D;  4HAC A;  4DV2 E;  4OO1 D;  3V2U C;  5A2Q Q;  2HFU A;  4JYA I;  1H7U A;  2Q2E B;  4GKJ E;  1Z0T A;  3Q6N A;  4DV0 I;  2XEX A;  2BA1 D;  1E3H A;  4DR7 E;  4DR7 I;  1NZ0 A;  3ZZ0 A;  5JEA A;  4JI4 I;  1HR0 I;  1MX0 A;  2PO1 B;  1UEK A;  2C37 A;  4X65 I;  4BA2 A;  2JE6 A;  1K47 A;  2HKJ A;  4NXM E;  2VQE E;  5ELW A;  2UUA I;  1MG7 A;  1IBK I;  3K1J A;  4LF9 I;  1N32 E;  3QT8 A;  4X62 E;  4DV3 E;  4KHP E;  1ZM3 A;  2O1U A;  2NN6 A;  4FW7 A;  4LCF A;  4MQY A;  3WU6 A;  3B82 A;  2PNL A;  1IBK E;  3PRY A;  4DV1 I;  3T1Y I;  1J5E I;  4B3S E;  2V2Q A;  4B3R E;  3ZKB A;  2BA0 G;  3K85 A;  4IZJ D;  4JI5 I;  3J81 Q;  4LFA E;  2UU9 I;  2WW4 A;  4DR6 I;  3ZM7 A;  3OTO I;  1Y4S A;  5JEA F;  2UUB E;  4IFD D;  1KIJ A;  4LF6 E;  2UXD E;  2IOQ A;  1BKN A;  1HK7 A;  4DUY I;  2J65 A;  5FLX Q;  2Z5B A;  2PO0 A;  2C38 B;  4ZVI A;  4PU9 A;  2UXD I;  1N32 I;  1RHY A;  4OO1 E;  3QT6 A;  3H4L A;  1IBM E;  3B4T A;  4DPX A;  4WUC A;  5BR8 E;  4DPY A;  4NBQ A;  1ZXM A;  4EMD A;  2E5L I;  4JI3 E;  4DPT A;  2JE6 B;  1UDO A;  1DAR A;  4JI5 E;  1USV A;  5JEA D;  4LFB E;  2AE8 A;  3PS3 A;  1FNM A;  3ZZU A;  4FW3 A;  5JEA E;  4AQY E;  2BR2 A;  1N0V C;  2F1D A;  4LF5 E;  3B78 A;  4N3O A;  1H7S A;  4BA1 B;  2AJ4 A;  4DV2 I;  5C0X B;  4DU7 A;  4JG4 A;  2PO2 A;  2NN6 D;  2JT2 A;  3Q1Q A;  4YY3 E;  1P42 A;  4DR1 E;  2NN6 E;  1RR9 A;  1XNQ I;  5DRQ A;  2UUA E;  3L7Z A;  2VQE I;  4IFD F;  3T1H I;  3DD6 A;  2UUC E;  1ZXN A;  1E3P A;  4LFB I;  5LMU E;  3OTO E;  3J81 C;  1XMO I;  4FW4 A;  1Y5Y A;  4HY1 A;  1VI7 A;  2BV3 A;  3JAM C;  4OO1 F;  2O1W A;  2UXC I;  4GKJ I;  4IFD B;  2DEJ A;  5IT9 C;  5LL6 R;  4AID A;  4DR4 I;  4JI1 E;  5DRR A;  1OYS A;  2A2C A;  4DPW A;  1NHI A;  2BA1 G;  2PNZ B;  3H1C A;  5FWK A;  4R1F A;  2WP8 B;  1Z59 A;  5IWA I;  5IWA E;  4K0K E;  4FN5 A;  4NXN E;  1KKH A;  1Z5C A;  1R6M A;  2HFS A;  3U1K A;  1KTV A;  2WP8 A;  4JI7 E;  4GKK I;  3HUL A;  2BM0 A;  5K36 D;  2UUB I;  4USK A;  3P76 A;  4X66 I;  5K36 E;  4Z7Y A;  2V8P A;  4DU8 A;  2E1R A;  2VQF I;  4FWH A;  1XHK A;  1ELO A;  1PIE A;  4XTJ A;  1XMO E;  4PRV A;  4B3R I;  1Z5A A;  5EKW A;  2GS8 A;  2ZBK B;  2PO2 B;  4J3D A;  5A2Q C;  2O3Z A;  2UUC I;  3P06 A;  4JV5 I;  2GO3 A;  4LCG A;  4FWD A;  4QNK A;  4X62 I;  3CWV A;  4LF7 I;  2BR2 B;  1IBL E;  3U1Y A;  4DR1 I;  5C0X C;  2CG9 A;  4MU1 A;  4LF5 I;  2ZM6 E;  1YH8 A;  1N33 E;  1FWL A;  3UHM A;  4UTG A;  4WUD A;  2HHH I;  1HNZ I;  4LF4 E;  3ZZT A;  1HR0 E;  4OO1 C;  2Z5E A;  1ZM9 A;  4DV5 I;  4DR2 E;  3K17 A;  1S16 A;  4U3B A;  3WU5 A;  4JI4 E;  1EI1 A;  5IT9 Q;  3WU3 A;  4LFC I;  3JAM Q;  4X64 E;  4DV7 E;  4MU0 A;  1N34 E;  4WUB A;  4IFD E;  3Q6M A;  4JI6 E;  4DV6 E;  1FJG I;  1R6L A;  5GMD A;  1IBL I;  4DUY E;  4JI2 I;  1QZR A;  1MU5 A;  4BA1 A;  3M7N G;  5K36 C; 
#chains in the Genus database with same CATH homology
 4LCH A;  4FW5 A;  3P3G A;  4U3D A;  3P3E A;  2JT2 A;  4OZE A;  2GO4 A;  1P42 A;  1YHC A;  5DRR A;  3NZK A;  2IER A;  4MDT A;  4U3B A;  5DRO A;  4ISA A;  5DRQ A;  4IS9 A;  4J3D A;  3PS2 A;  2O3Z A;  2GO3 A;  4LCG A;  4FW6 A;  3PS3 A;  3P3C A;  4FW3 A;  3U1Y A;  4FW7 A;  4LCF A;  4MQY A;  3PS1 A;  5DRP A;  1XXE A;  4FW4 A;  1YH8 A;  2J65 A;  3UHM A;  2VES A;  2IES A;  4OKG A;  3P76 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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