1YI2W

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 49
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
154
structure length
154
Chain Sequence
MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 49
structure length 154
sequence length 154
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.15.30 Mainly Alpha Orthogonal Bundle 3-methyladenine DNA Glycosylase II; Chain A, domain 3 3-methyladenine DNA Glycosylase II; Chain A, domain 3 1yi2W02
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 1yi2W01
2QEXW 4U67W 3CXCV 1K73X 3J7ZZ 3CCUW 1Q81X 5HL7W 1VQLW 3CF5W 3CCRW 4WFNW 1VQ7W 5GADa 5GAHa 1VQ4W 3CCJW 3CCEW 3G6EW 4IOAW 5DM6W 1KD1X 3CMAW 1VQ9W 1W2BV 3CCQW 5JVGW 3PIPW 1Q7YX 1VQMW 5DM7W 2ZJQW 1KC8X 1QVGV 2OTJW 3G71W 1NJIX 1JJ2V 4WFBW 3I55W 4WFAW 3CMEW 1VQ6W 1YJ9W 1M1KX 1VQ8W 3I56W 1K9MX 1YITW 1VQOW 5GAGa 1K8AX 1QVFV 1N8RX 1YJWW 3CCLW 1Q86X 4IO9W 3G4SW 1VQ5W 1M90X 2QA4W 3DLLW 3PIOW 2OTLW 1VQNW 4WCEW 1YHQW 1YJNW 1YIJW 4WF9W 1KQSV 5JVHW 2ZJRW 4UY8Z 3CCSW 1VQKW 5GAEa 1YI2W 1BXYA 1Q82X 3CPWV 3CCVW 3CC7W 3CC2W 4IOCW 3CC4W 3OW2V 1S72W 3CCMW 2ZJPW 3CD6W 1VQPW
chains in the Genus database with same CATH superfamily
2QEXW 2WA9A 4U67W 3ZFZA 3CXCV 1K73X 1DD3A 3J7ZZ 3CCUW 1MWSA 1Q81X 5HL7W 1VQLW 3CF5W 5M18A 3GW1A 3CCRW 4WFNW 1VQ7W 5GADa 5GAHa 1VQ4W 3CCJW 3CCEW 3G3PA 3G6EW 4IOAW 4C1NA 1MBUC 5DM6W 1KD1X 1RQUA 5M1AA 3CMAW 1RQVA 1VQ9W 3D3IA 3O1FA 1W2BV 3CCQW 3DNJA 4CPKA 3W7XA 5JVGW 3PIPW 1Q7YX 1VQMW 5DM7W 2ZJQW 1KC8X 1QVGV 2OTJW 3G71W 1NJIX 1JJ2V 3I55W 4WFBW 4WFAW 3CMEW 3W7WA 4DKIA 1DD4A 5CA3A 1CTFA 1VQ6W 1YJ9W 1M1KX 2W9RA 5M19A 4YJMA 1VQ8W 3I56W 1K9MX 1YITW 3ZG5A 3G1BA 5GW7A 1VQOW 5GAGa 3O2OA 1K8AX 1QVFV 3O2HA 1N8RX 1YJWW 1MBVB 3CCLW 1Q86X 4IO9W 3W7SA 4YJXA 3W7TA 3G4SW 1VQ5W 1M90X 3W7UA 2WA8A 2QA4W 3DLLW 3PIOW 2OTLW 1VQNW 4WCEW 1YHQW 1R6OC 3G19A 1YJNW 1YIJW 3GQ1A 4WF9W 1MWTA 3O2BA 1MWRA 1MBXC 1KQSV 3ZG0A 4BL3A 1MWUA 5JVHW 3GQ0A 2ZJRW 1RQSA 4CJNA 4UY8Z 3CCSW 1VQKW 4YKAA 5GAEa 1YI2W 1BXYA 1Q82X 3CPWV 3CCVW 3CC7W 3CC2W 4IOCW 1LZWA 3CC4W 1VQQA 4BL2A 3OW2V 1S72W 3CCMW 2ZJPW 3O1FB 1MG9A 1R6QC 3CD6W 1VQPW
chains in the Genus database with same CATH topology
2QEXW 4U67W 3CXCV 1K73X 3J7ZZ 3CCUW 1Q81X 5HL7W 1VQLW 3CF5W 3CCRW 4WFNW 1VQ7W 5GADa 5GAHa 1VQ4W 3CCJW 3CCEW 3G6EW 4IOAW 4C1NA 5DM6W 1KD1X 3CMAW 1VQ9W 1W2BV 3CCQW 5JVGW 3PIPW 1Q7YX 1VQMW 5DM7W 2ZJQW 1KC8X 1QVGV 2OTJW 3G71W 1NJIX 1JJ2V 4WFBW 3I55W 4WFAW 3CMEW 1VQ6W 1YJ9W 1M1KX 1VQ8W 3I56W 1K9MX 1YITW 1VQOW 5GAGa 1K8AX 1QVFV 1N8RX 1YJWW 3CCLW 1Q86X 4IO9W 3G4SW 1VQ5W 1M90X 2QA4W 3DLLW 3PIOW 2OTLW 1VQNW 4WCEW 1YHQW 1YJNW 1YIJW 4WF9W 1KQSV 5JVHW 2ZJRW 4UY8Z 3CCSW 1VQKW 5GAEa 1YI2W 1BXYA 1Q82X 3CPWV 3CCVW 3CC7W 3CC2W 4IOCW 3CC4W 3OW2V 1S72W 3CCMW 2ZJPW 3CD6W 1VQPW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QEX W;  4U67 W;  3CXC V;  1K73 X;  3J7Z Z;  3CCU W;  1Q81 X;  5HL7 W;  1VQL W;  3CF5 W;  3CCR W;  4WFN W;  1VQ7 W;  5GAD a;  5GAH a;  1VQ4 W;  3CCJ W;  3CCE W;  3G6E W;  4IOA W;  5DM6 W;  1KD1 X;  3CMA W;  1VQ9 W;  1W2B V;  3CCQ W;  5JVG W;  3PIP W;  1Q7Y X;  1VQM W;  5DM7 W;  2ZJQ W;  1KC8 X;  1QVG V;  2OTJ W;  3G71 W;  1NJI X;  1JJ2 V;  4WFB W;  3I55 W;  4WFA W;  3CME W;  1VQ6 W;  1YJ9 W;  1M1K X;  1VQ8 W;  3I56 W;  1K9M X;  1YIT W;  1VQO W;  5GAG a;  1K8A X;  1QVF V;  1N8R X;  1YJW W;  3CCL W;  1Q86 X;  4IO9 W;  3G4S W;  1VQ5 W;  1M90 X;  2QA4 W;  3DLL W;  3PIO W;  2OTL W;  1VQN W;  4WCE W;  1YHQ W;  1YJN W;  1YIJ W;  4WF9 W;  1KQS V;  5JVH W;  2ZJR W;  4UY8 Z;  3CCS W;  1VQK W;  5GAE a;  1YI2 W;  1BXY A;  1Q82 X;  3CPW V;  3CCV W;  3CC7 W;  3CC2 W;  4IOC W;  3CC4 W;  3OW2 V;  1S72 W;  3CCM W;  2ZJP W;  3CD6 W;  1VQP W; 
#chains in the Genus database with same CATH topology
 2QEX W;  2WA9 A;  4U67 W;  3ZFZ A;  3CXC V;  1K73 X;  1DD3 A;  3J7Z Z;  3CCU W;  1MWS A;  1Q81 X;  5HL7 W;  1VQL W;  3CF5 W;  5M18 A;  3GW1 A;  3CCR W;  4WFN W;  1VQ7 W;  5GAD a;  5GAH a;  1VQ4 W;  3CCJ W;  3CCE W;  3G3P A;  3G6E W;  4IOA W;  4C1N A;  1MBU C;  5DM6 W;  1KD1 X;  1RQU A;  5M1A A;  3CMA W;  1RQV A;  1VQ9 W;  3D3I A;  3O1F A;  1W2B V;  3CCQ W;  3DNJ A;  4CPK A;  3W7X A;  5JVG W;  3PIP W;  1Q7Y X;  1VQM W;  5DM7 W;  2ZJQ W;  1KC8 X;  1QVG V;  2OTJ W;  3G71 W;  1NJI X;  1JJ2 V;  3I55 W;  4WFB W;  4WFA W;  3CME W;  3W7W A;  4DKI A;  1DD4 A;  5CA3 A;  1CTF A;  1VQ6 W;  1YJ9 W;  1M1K X;  2W9R A;  5M19 A;  4YJM A;  1VQ8 W;  3I56 W;  1K9M X;  1YIT W;  3ZG5 A;  3G1B A;  5GW7 A;  1VQO W;  5GAG a;  3O2O A;  1K8A X;  1QVF V;  3O2H A;  1N8R X;  1YJW W;  1MBV B;  3CCL W;  1Q86 X;  4IO9 W;  3W7S A;  4YJX A;  3W7T A;  3G4S W;  1VQ5 W;  1M90 X;  3W7U A;  2WA8 A;  2QA4 W;  3DLL W;  3PIO W;  2OTL W;  1VQN W;  4WCE W;  1YHQ W;  1R6O C;  3G19 A;  1YJN W;  1YIJ W;  3GQ1 A;  4WF9 W;  1MWT A;  3O2B A;  1MWR A;  1MBX C;  1KQS V;  3ZG0 A;  4BL3 A;  1MWU A;  5JVH W;  3GQ0 A;  2ZJR W;  1RQS A;  4CJN A;  4UY8 Z;  3CCS W;  1VQK W;  4YKA A;  5GAE a;  1YI2 W;  1BXY A;  1Q82 X;  3CPW V;  3CCV W;  3CC7 W;  3CC2 W;  4IOC W;  1LZW A;  3CC4 W;  1VQQ A;  4BL2 A;  3OW2 V;  1S72 W;  3CCM W;  2ZJP W;  3O1F B;  1MG9 A;  1R6Q C;  3CD6 W;  1VQP W; 
#chains in the Genus database with same CATH homology
 2QEX W;  4U67 W;  3CXC V;  1K73 X;  3J7Z Z;  3CCU W;  1Q81 X;  5HL7 W;  1VQL W;  3CF5 W;  3CCR W;  4WFN W;  1VQ7 W;  5GAD a;  5GAH a;  1VQ4 W;  3CCJ W;  3CCE W;  3G6E W;  4IOA W;  4C1N A;  5DM6 W;  1KD1 X;  3CMA W;  1VQ9 W;  1W2B V;  3CCQ W;  5JVG W;  3PIP W;  1Q7Y X;  1VQM W;  5DM7 W;  2ZJQ W;  1KC8 X;  1QVG V;  2OTJ W;  3G71 W;  1NJI X;  1JJ2 V;  4WFB W;  3I55 W;  4WFA W;  3CME W;  1VQ6 W;  1YJ9 W;  1M1K X;  1VQ8 W;  3I56 W;  1K9M X;  1YIT W;  1VQO W;  5GAG a;  1K8A X;  1QVF V;  1N8R X;  1YJW W;  3CCL W;  1Q86 X;  4IO9 W;  3G4S W;  1VQ5 W;  1M90 X;  2QA4 W;  3DLL W;  3PIO W;  2OTL W;  1VQN W;  4WCE W;  1YHQ W;  1YJN W;  1YIJ W;  4WF9 W;  1KQS V;  5JVH W;  2ZJR W;  4UY8 Z;  3CCS W;  1VQK W;  5GAE a;  1YI2 W;  1BXY A;  1Q82 X;  3CPW V;  3CCV W;  3CC7 W;  3CC2 W;  4IOC W;  3CC4 W;  3OW2 V;  1S72 W;  3CCM W;  2ZJP W;  3CD6 W;  1VQP W; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...