1YIJE

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE01
1VQKE 4IOCE 1YIJE 3I56E 4WFAE 3I55E 3G6EE 2QEXE 1YJ9E 3CMEE 1W2BE 3CC2E 1M1KG 1VQLE 1VQ9E 1NJIG 2CQLA 2ZJQE 1Q81G 3PIPE 4WF9E 1YJNE 3CCVE 3CCRE 1QVFE 1JJ2E 4U67E 2OTJE 2QA4E 3PIOE 3CMAE 1VQ5E 1Q86G 2ZJRE 3CCUE 3CCQE 1VQ4E 1Q7YG 1VQ6E 5HL7E 5GADG 3CF5E 2OTLE 1Q82G 4UY8G 3J7ZG 5H1SI 4IO9E 5DM6E 2ZJPE 1KQSE 3DLLE 3G4SE 3CXCE 3CPWE 3CCLE 5JVGE 1K73G 1VQPE 1VQOE 1YJWE 3OW2E 4WCEE 1KD1G 1YHQE 1YI2E 4WFNE 1S72E 1VQME 4WFBE 3CC4E 1YITE 1QVGE 3CCME 4IOAE 3G71E 3CCJE 1VQ8E 3CC7E 1K9MG 3CD6E 5MLCH 5GAEG 5DM7E 3CCEE 1K8AG 5GAGG 1VQNE 5GAHG 1M90G 1VQ7E 5AN9B 3CCSE 1RL6A 1KC8G 5JVHE 1N8RG
chains in the Genus database with same CATH superfamily
1VQKE 4IOCE 1YIJE 3I56E 4WFAE 3I55E 3G6EE 2QEXE 1YJ9E 3CMEE 1W2BE 3CC2E 2OL7A 1M1KG 1OSPO 3CKFA 1VQLE 1VQ9E 2G8CO 1NJIG 2CQLA 5B10O 2OL6O 2ZJQE 1Q81G 3PIPE 4WF9E 1YJNE 3CCVE 2I5ZO 3CCRE 1QVFE 1JJ2E 2OYBO 4U67E 2OTJE 2QA4E 3PIOE 2OL8O 3CMAE 5B11O 1VQ5E 1Q86G 2ZJRE 3CCUE 3CCQE 2OY7A 1VQ4E 1Q7YG 1VQ6E 5HL7E 5GADG 2FKGA 3CKGA 3CF5E 2OTLE 1Q82G 2OY8A 4UY8G 3J7ZG 2AF5A 5H1SI 4IO9E 1FJ1E 2OY1O 5DM6E 2ZJPE 1KQSE 3DLLE 3G4SE 3CXCE 2OY5O 3CPWE 3CCLE 5JVGE 1K73G 2I5VO 1VQPE 1VQOE 1YJWE 3OW2E 4WCEE 1KD1G 5B2AO 1YHQE 3EC5A 1YI2E 4WFNE 1S72E 1VQME 3AUMO 4WFBE 3CC4E 1YITE 1QVGE 3CCME 2PI3O 1RJLC 4IOAE 3G71E 3CCJE 1VQ8E 3CC7E 3IGEA 1K9MG 3CD6E 5MLCH 5GAEG 5DM7E 3CCEE 5B3MO 1K8AG 5GAGG 2FKJA 1VQNE 5GAHG 1M90G 1VQ7E 5AN9B 3CCSE 2HKDA 1P4PA 1RL6A 3IG9A 1KC8G 5JVHE 1N8RG
chains in the Genus database with same CATH topology
1VQKE 4IOCE 1YIJE 3I56E 4WFAE 3I55E 3G6EE 2QEXE 1YJ9E 3CMEE 1W2BE 3CC2E 1M1KG 1VQLE 1VQ9E 1NJIG 2CQLA 2ZJQE 1Q81G 3PIPE 4WF9E 1YJNE 3CCVE 3CCRE 1QVFE 1JJ2E 4U67E 2OTJE 2QA4E 3PIOE 3CMAE 1VQ5E 1Q86G 2ZJRE 3CCUE 3CCQE 1VQ4E 1Q7YG 1VQ6E 5HL7E 5GADG 3CF5E 2OTLE 1Q82G 4UY8G 3J7ZG 5H1SI 4IO9E 5DM6E 2ZJPE 1KQSE 3DLLE 3G4SE 3CXCE 3CPWE 3CCLE 5JVGE 1K73G 1VQPE 1VQOE 1YJWE 3OW2E 4WCEE 1KD1G 1YHQE 1YI2E 4WFNE 1S72E 1VQME 4WFBE 3CC4E 1YITE 1QVGE 3CCME 4IOAE 3G71E 3CCJE 1VQ8E 3CC7E 1K9MG 3CD6E 5MLCH 5GAEG 5DM7E 3CCEE 1K8AG 5GAGG 1VQNE 5GAHG 1M90G 1VQ7E 5AN9B 3CCSE 1RL6A 1KC8G 5JVHE 1N8RG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQK E;  4IOC E;  1YIJ E;  3I56 E;  4WFA E;  3I55 E;  3G6E E;  2QEX E;  1YJ9 E;  3CME E;  1W2B E;  3CC2 E;  1M1K G;  1VQL E;  1VQ9 E;  1NJI G;  2CQL A;  2ZJQ E;  1Q81 G;  3PIP E;  4WF9 E;  1YJN E;  3CCV E;  3CCR E;  1QVF E;  1JJ2 E;  4U67 E;  2OTJ E;  2QA4 E;  3PIO E;  3CMA E;  1VQ5 E;  1Q86 G;  2ZJR E;  3CCU E;  3CCQ E;  1VQ4 E;  1Q7Y G;  1VQ6 E;  5HL7 E;  5GAD G;  3CF5 E;  2OTL E;  1Q82 G;  4UY8 G;  3J7Z G;  5H1S I;  4IO9 E;  5DM6 E;  2ZJP E;  1KQS E;  3DLL E;  3G4S E;  3CXC E;  3CPW E;  3CCL E;  5JVG E;  1K73 G;  1VQP E;  1VQO E;  1YJW E;  3OW2 E;  4WCE E;  1KD1 G;  1YHQ E;  1YI2 E;  4WFN E;  1S72 E;  1VQM E;  4WFB E;  3CC4 E;  1YIT E;  1QVG E;  3CCM E;  4IOA E;  3G71 E;  3CCJ E;  1VQ8 E;  3CC7 E;  1K9M G;  3CD6 E;  5MLC H;  5GAE G;  5DM7 E;  3CCE E;  1K8A G;  5GAG G;  1VQN E;  5GAH G;  1M90 G;  1VQ7 E;  5AN9 B;  3CCS E;  1RL6 A;  1KC8 G;  5JVH E;  1N8R G; 
#chains in the Genus database with same CATH topology
 1VQK E;  4IOC E;  1YIJ E;  3I56 E;  4WFA E;  3I55 E;  3G6E E;  2QEX E;  1YJ9 E;  3CME E;  1W2B E;  3CC2 E;  2OL7 A;  1M1K G;  1OSP O;  3CKF A;  1VQL E;  1VQ9 E;  2G8C O;  1NJI G;  2CQL A;  5B10 O;  2OL6 O;  2ZJQ E;  1Q81 G;  3PIP E;  4WF9 E;  1YJN E;  3CCV E;  2I5Z O;  3CCR E;  1QVF E;  1JJ2 E;  2OYB O;  4U67 E;  2OTJ E;  2QA4 E;  3PIO E;  2OL8 O;  3CMA E;  5B11 O;  1VQ5 E;  1Q86 G;  2ZJR E;  3CCU E;  3CCQ E;  2OY7 A;  1VQ4 E;  1Q7Y G;  1VQ6 E;  5HL7 E;  5GAD G;  2FKG A;  3CKG A;  3CF5 E;  2OTL E;  1Q82 G;  2OY8 A;  4UY8 G;  3J7Z G;  2AF5 A;  5H1S I;  4IO9 E;  1FJ1 E;  2OY1 O;  5DM6 E;  2ZJP E;  1KQS E;  3DLL E;  3G4S E;  3CXC E;  2OY5 O;  3CPW E;  3CCL E;  5JVG E;  1K73 G;  2I5V O;  1VQP E;  1VQO E;  1YJW E;  3OW2 E;  4WCE E;  1KD1 G;  5B2A O;  1YHQ E;  3EC5 A;  1YI2 E;  4WFN E;  1S72 E;  1VQM E;  3AUM O;  4WFB E;  3CC4 E;  1YIT E;  1QVG E;  3CCM E;  2PI3 O;  1RJL C;  4IOA E;  3G71 E;  3CCJ E;  1VQ8 E;  3CC7 E;  3IGE A;  1K9M G;  3CD6 E;  5MLC H;  5GAE G;  5DM7 E;  3CCE E;  5B3M O;  1K8A G;  5GAG G;  2FKJ A;  1VQN E;  5GAH G;  1M90 G;  1VQ7 E;  5AN9 B;  3CCS E;  2HKD A;  1P4P A;  1RL6 A;  3IG9 A;  1KC8 G;  5JVH E;  1N8R G; 
#chains in the Genus database with same CATH homology
 1VQK E;  4IOC E;  1YIJ E;  3I56 E;  4WFA E;  3I55 E;  3G6E E;  2QEX E;  1YJ9 E;  3CME E;  1W2B E;  3CC2 E;  1M1K G;  1VQL E;  1VQ9 E;  1NJI G;  2CQL A;  2ZJQ E;  1Q81 G;  3PIP E;  4WF9 E;  1YJN E;  3CCV E;  3CCR E;  1QVF E;  1JJ2 E;  4U67 E;  2OTJ E;  2QA4 E;  3PIO E;  3CMA E;  1VQ5 E;  1Q86 G;  2ZJR E;  3CCU E;  3CCQ E;  1VQ4 E;  1Q7Y G;  1VQ6 E;  5HL7 E;  5GAD G;  3CF5 E;  2OTL E;  1Q82 G;  4UY8 G;  3J7Z G;  5H1S I;  4IO9 E;  5DM6 E;  2ZJP E;  1KQS E;  3DLL E;  3G4S E;  3CXC E;  3CPW E;  3CCL E;  5JVG E;  1K73 G;  1VQP E;  1VQO E;  1YJW E;  3OW2 E;  4WCE E;  1KD1 G;  1YHQ E;  1YI2 E;  4WFN E;  1S72 E;  1VQM E;  4WFB E;  3CC4 E;  1YIT E;  1QVG E;  3CCM E;  4IOA E;  3G71 E;  3CCJ E;  1VQ8 E;  3CC7 E;  1K9M G;  3CD6 E;  5MLC H;  5GAE G;  5DM7 E;  3CCE E;  1K8A G;  5GAG G;  1VQN E;  5GAH G;  1M90 G;  1VQ7 E;  5AN9 B;  3CCS E;  1RL6 A;  1KC8 G;  5JVH E;  1N8R G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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