1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
2DFIA 3PKCA 1C22A 4U1BA 4U69A 4ZWUA 1QXZA 1A16A 5E5BA 4U6ZA 4QR8A 4PV4A 3BIPA 2BHDA 4IKSA 4IU6A 3CB5A 4FO7A 5CDVA 2GG0A 3D27A 2BWXA 1KQ9A 3BIQA 2Q94A 4MATA 4RZYA 1YW9A 2P98A 2Q8KA 4JUQA 2B3KA 2BWWA 2BWUA 3PKAA 4B28A 4KM3A 3Q6DA 2Q96A 4FLJA 5FCFA 1BOAA 4U6CA 2Q92A 3FM3A 1PV9A 1QXYA 1N51A 1WN1A 3MR1A 1R58A 1YW7A 2V3XA 3FMQA 2Q95A 4S2TP 2GA2A 1M35A 1Y1NA 2BWVA 4A6WA 3MATA 4S2RP 2BHAA 2BWTA 4IF7A 4U71A 1CHMA 1C24A 1YJ3A 2GU5A 2GU6A 2BB7A 2B3HA 1W7VA 4IKUA 2NQ6A 2EVOA 2GTXA 5CNXA 4A6VA 3L24A 3IG4A 4RZZA 2V6CA 2EA2A 1C21A 2G6PA 2V3ZA 2ADUA 5D6EA 2MATA 4U6WA 1KQ0A 3TB5A 2NQ7A 3MX6A 1WLRA 4FUKA 3RVAA 1BN5A 3IU9A 1XGOA 2V3YA 5CDEA 4FLIA 3IU7A 1XGSA 4ZWPA 4U6EA 4Z7MA 1XGMA 2GG5A 4IKTA 4S00A 3S6BA 5JFRA 3PKDA 1R5HA 2GGBA 3FMRA 4IKRA 2EVMA 5JHUA 4FKCA 3CTZA 1C27A 2EVCA 4ZWOA 4R60A 5CIKA 2Q93A 3L7GA 1WKMA 1WY2A 2GU7A 4HXXA 4FLLA 2GG8A 4U75A 1KP0A 4U6JA 1C23A 2ZSGA 2GG7A 4IECA 2GG2A 1QXWA 1XGNA 1W2MA 3CB6A 4OOKA 2EA4A 1B59A 4RGZ1 1YVMA 2GZ5A 1O0XA 2HOWA 2P9AA 2BN7A 3PKEA 3TAVA 5FCHA 3BITA 2GG3A 1WBQA 1B6AA 1WL9A 2GG9A 2BWSA 4FO8A 4U70A 3PKBA 4U76A 5JI6A 4PNCA 5CDLA 2IW2A 4FLKA 2GU4A 1QZYA 5CE6A 2OAZA 4IPAA 4ZNGA 5CLSA 4S01A 1JAWA 2BWYA 1R5GA 4IDYA 1WL6A 2B3LA 2BHCA 2GGCA 5D6FA 4EGEA 1XNZA 1MATA 2P99A 2BH3A 3IU8A 4U73A 2BHBA 2OKNA 3RORA 1YW8A
chains in the Genus database with same CATH superfamily
2DFIA 3PKCA 1C22A 4U1BA 4U69A 4ZWUA 1QXZA 1A16A 5E5BA 4U6ZA 4QR8A 4PV4A 3BIPA 2BHDA 4IKSA 4IU6A 3CB5A 4FO7A 5CDVA 2GG0A 3D27A 2BWXA 1KQ9A 3BIQA 2Q94A 4MATA 4RZYA 1YW9A 2P98A 2Q8KA 4JUQA 2B3KA 2BWWA 2BWUA 3PKAA 4B28A 4KM3A 3Q6DA 2Q96A 4FLJA 5FCFA 1BOAA 4U6CA 2Q92A 3FM3A 1PV9A 1QXYA 1N51A 1WN1A 3MR1A 1R58A 1YW7A 2V3XA 3FMQA 2Q95A 4S2TP 2GA2A 1M35A 1Y1NA 2BWVA 4A6WA 3MATA 4S2RP 2BHAA 2BWTA 4IF7A 4U71A 1CHMA 1C24A 1YJ3A 2GU5A 2GU6A 2BB7A 2B3HA 1W7VA 4IKUA 2NQ6A 2EVOA 2GTXA 5CNXA 4A6VA 3L24A 3IG4A 4RZZA 2V6CA 2EA2A 1C21A 2G6PA 2V3ZA 2ADUA 5D6EA 2MATA 4U6WA 1KQ0A 3TB5A 2NQ7A 3MX6A 1WLRA 4FUKA 3RVAA 1BN5A 3IU9A 1XGOA 2V3YA 5CDEA 4FLIA 3IU7A 1XGSA 4ZWPA 4U6EA 4Z7MA 1XGMA 2GG5A 4IKTA 4S00A 3S6BA 5JFRA 3PKDA 1R5HA 2GGBA 3FMRA 4IKRA 2EVMA 5JHUA 4FKCA 3CTZA 1C27A 2EVCA 4ZWOA 4R60A 5CIKA 2Q93A 3L7GA 1WKMA 1WY2A 2GU7A 4HXXA 4FLLA 2GG8A 4U75A 1KP0A 4U6JA 1C23A 2ZSGA 2GG7A 4IECA 2GG2A 1QXWA 1XGNA 1W2MA 3CB6A 4OOKA 2EA4A 1B59A 4RGZ1 1YVMA 2GZ5A 1O0XA 2HOWA 2P9AA 2BN7A 3PKEA 3TAVA 5FCHA 3BITA 2GG3A 1WBQA 1B6AA 1WL9A 2GG9A 2BWSA 4FO8A 4U70A 3PKBA 4U76A 5JI6A 4PNCA 5CDLA 2IW2A 4FLKA 2GU4A 1QZYA 5CE6A 2OAZA 4IPAA 4ZNGA 5CLSA 4S01A 1JAWA 2BWYA 1R5GA 4IDYA 1WL6A 2B3LA 2BHCA 2GGCA 5D6FA 4EGEA 1XNZA 1MATA 2P99A 2BH3A 3IU8A 4U73A 2BHBA 2OKNA 3RORA 1YW8A
chains in the Genus database with same CATH topology
2DFIA 3PKCA 1C22A 4U1BA 4U69A 4ZWUA 1QXZA 1A16A 5E5BA 4U6ZA 4QR8A 4PV4A 3BIPA 2BHDA 4IKSA 4IU6A 3CB5A 4FO7A 5CDVA 2GG0A 3D27A 2BWXA 1KQ9A 3BIQA 2Q94A 4MATA 4RZYA 1YW9A 2P98A 2Q8KA 4JUQA 2B3KA 2BWWA 2BWUA 3PKAA 4B28A 4KM3A 3Q6DA 2Q96A 4FLJA 5FCFA 1BOAA 4U6CA 2Q92A 3FM3A 1PV9A 1QXYA 1N51A 1WN1A 3MR1A 1R58A 1YW7A 2V3XA 3FMQA 2Q95A 4S2TP 2GA2A 1M35A 1Y1NA 2BWVA 4A6WA 3MATA 4S2RP 2BHAA 2BWTA 4IF7A 4U71A 1CHMA 1C24A 1YJ3A 2GU5A 2GU6A 2BB7A 2B3HA 1W7VA 4IKUA 2NQ6A 2EVOA 2GTXA 5CNXA 4A6VA 3L24A 3IG4A 4RZZA 2V6CA 2EA2A 1C21A 2G6PA 2V3ZA 2ADUA 5D6EA 2MATA 4U6WA 1KQ0A 3TB5A 2NQ7A 3MX6A 1WLRA 4FUKA 3RVAA 1BN5A 3IU9A 1XGOA 2V3YA 5CDEA 4FLIA 3IU7A 1XGSA 4ZWPA 4U6EA 4Z7MA 1XGMA 2GG5A 4IKTA 4S00A 3S6BA 5JFRA 3PKDA 1R5HA 2GGBA 3FMRA 4IKRA 2EVMA 5JHUA 4FKCA 3CTZA 1C27A 2EVCA 4ZWOA 4R60A 5CIKA 2Q93A 3L7GA 1WKMA 1WY2A 2GU7A 4HXXA 4FLLA 2GG8A 4U75A 1KP0A 4U6JA 1C23A 2ZSGA 2GG7A 4IECA 2GG2A 1QXWA 1XGNA 1W2MA 3CB6A 4OOKA 2EA4A 1B59A 4RGZ1 1YVMA 2GZ5A 1O0XA 2HOWA 2P9AA 2BN7A 3PKEA 3TAVA 5FCHA 3BITA 2GG3A 1WBQA 1B6AA 1WL9A 2GG9A 2BWSA 4FO8A 4U70A 3PKBA 4U76A 5JI6A 4PNCA 5CDLA 2IW2A 4FLKA 2GU4A 1QZYA 5CE6A 2OAZA 4IPAA 4ZNGA 5CLSA 4S01A 1JAWA 2BWYA 1R5GA 4IDYA 1WL6A 2B3LA 2BHCA 2GGCA 5D6FA 4EGEA 1XNZA 1MATA 2P99A 2BH3A 3IU8A 4U73A 2BHBA 2OKNA 3RORA 1YW8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DFI A;  3PKC A;  1C22 A;  4U1B A;  4U69 A;  4ZWU A;  1QXZ A;  1A16 A;  5E5B A;  4U6Z A;  4QR8 A;  4PV4 A;  3BIP A;  2BHD A;  4IKS A;  4IU6 A;  3CB5 A;  4FO7 A;  5CDV A;  2GG0 A;  3D27 A;  2BWX A;  1KQ9 A;  3BIQ A;  2Q94 A;  4MAT A;  4RZY A;  1YW9 A;  2P98 A;  2Q8K A;  4JUQ A;  2B3K A;  2BWW A;  2BWU A;  3PKA A;  4B28 A;  4KM3 A;  3Q6D A;  2Q96 A;  4FLJ A;  5FCF A;  1BOA A;  4U6C A;  2Q92 A;  3FM3 A;  1PV9 A;  1QXY A;  1N51 A;  1WN1 A;  3MR1 A;  1R58 A;  1YW7 A;  2V3X A;  3FMQ A;  2Q95 A;  4S2T P;  2GA2 A;  1M35 A;  1Y1N A;  2BWV A;  4A6W A;  3MAT A;  4S2R P;  2BHA A;  2BWT A;  4IF7 A;  4U71 A;  1CHM A;  1C24 A;  1YJ3 A;  2GU5 A;  2GU6 A;  2BB7 A;  2B3H A;  1W7V A;  4IKU A;  2NQ6 A;  2EVO A;  2GTX A;  5CNX A;  4A6V A;  3L24 A;  3IG4 A;  4RZZ A;  2V6C A;  2EA2 A;  1C21 A;  2G6P A;  2V3Z A;  2ADU A;  5D6E A;  2MAT A;  4U6W A;  1KQ0 A;  3TB5 A;  2NQ7 A;  3MX6 A;  1WLR A;  4FUK A;  3RVA A;  1BN5 A;  3IU9 A;  1XGO A;  2V3Y A;  5CDE A;  4FLI A;  3IU7 A;  1XGS A;  4ZWP A;  4U6E A;  4Z7M A;  1XGM A;  2GG5 A;  4IKT A;  4S00 A;  3S6B A;  5JFR A;  3PKD A;  1R5H A;  2GGB A;  3FMR A;  4IKR A;  2EVM A;  5JHU A;  4FKC A;  3CTZ A;  1C27 A;  2EVC A;  4ZWO A;  4R60 A;  5CIK A;  2Q93 A;  3L7G A;  1WKM A;  1WY2 A;  2GU7 A;  4HXX A;  4FLL A;  2GG8 A;  4U75 A;  1KP0 A;  4U6J A;  1C23 A;  2ZSG A;  2GG7 A;  4IEC A;  2GG2 A;  1QXW A;  1XGN A;  1W2M A;  3CB6 A;  4OOK A;  2EA4 A;  1B59 A;  4RGZ 1;  1YVM A;  2GZ5 A;  1O0X A;  2HOW A;  2P9A A;  2BN7 A;  3PKE A;  3TAV A;  5FCH A;  3BIT A;  2GG3 A;  1WBQ A;  1B6A A;  1WL9 A;  2GG9 A;  2BWS A;  4FO8 A;  4U70 A;  3PKB A;  4U76 A;  5JI6 A;  4PNC A;  5CDL A;  2IW2 A;  4FLK A;  2GU4 A;  1QZY A;  5CE6 A;  2OAZ A;  4IPA A;  4ZNG A;  5CLS A;  4S01 A;  1JAW A;  2BWY A;  1R5G A;  4IDY A;  1WL6 A;  2B3L A;  2BHC A;  2GGC A;  5D6F A;  4EGE A;  1XNZ A;  1MAT A;  2P99 A;  2BH3 A;  3IU8 A;  4U73 A;  2BHB A;  2OKN A;  3ROR A;  1YW8 A; 
#chains in the Genus database with same CATH topology
 2DFI A;  3PKC A;  1C22 A;  4U1B A;  4U69 A;  4ZWU A;  1QXZ A;  1A16 A;  5E5B A;  4U6Z A;  4QR8 A;  4PV4 A;  3BIP A;  2BHD A;  4IKS A;  4IU6 A;  3CB5 A;  4FO7 A;  5CDV A;  2GG0 A;  3D27 A;  2BWX A;  1KQ9 A;  3BIQ A;  2Q94 A;  4MAT A;  4RZY A;  1YW9 A;  2P98 A;  2Q8K A;  4JUQ A;  2B3K A;  2BWW A;  2BWU A;  3PKA A;  4B28 A;  4KM3 A;  3Q6D A;  2Q96 A;  4FLJ A;  5FCF A;  1BOA A;  4U6C A;  2Q92 A;  3FM3 A;  1PV9 A;  1QXY A;  1N51 A;  1WN1 A;  3MR1 A;  1R58 A;  1YW7 A;  2V3X A;  3FMQ A;  2Q95 A;  4S2T P;  2GA2 A;  1M35 A;  1Y1N A;  2BWV A;  4A6W A;  3MAT A;  4S2R P;  2BHA A;  2BWT A;  4IF7 A;  4U71 A;  1CHM A;  1C24 A;  1YJ3 A;  2GU5 A;  2GU6 A;  2BB7 A;  2B3H A;  1W7V A;  4IKU A;  2NQ6 A;  2EVO A;  2GTX A;  5CNX A;  4A6V A;  3L24 A;  3IG4 A;  4RZZ A;  2V6C A;  2EA2 A;  1C21 A;  2G6P A;  2V3Z A;  2ADU A;  5D6E A;  2MAT A;  4U6W A;  1KQ0 A;  3TB5 A;  2NQ7 A;  3MX6 A;  1WLR A;  4FUK A;  3RVA A;  1BN5 A;  3IU9 A;  1XGO A;  2V3Y A;  5CDE A;  4FLI A;  3IU7 A;  1XGS A;  4ZWP A;  4U6E A;  4Z7M A;  1XGM A;  2GG5 A;  4IKT A;  4S00 A;  3S6B A;  5JFR A;  3PKD A;  1R5H A;  2GGB A;  3FMR A;  4IKR A;  2EVM A;  5JHU A;  4FKC A;  3CTZ A;  1C27 A;  2EVC A;  4ZWO A;  4R60 A;  5CIK A;  2Q93 A;  3L7G A;  1WKM A;  1WY2 A;  2GU7 A;  4HXX A;  4FLL A;  2GG8 A;  4U75 A;  1KP0 A;  4U6J A;  1C23 A;  2ZSG A;  2GG7 A;  4IEC A;  2GG2 A;  1QXW A;  1XGN A;  1W2M A;  3CB6 A;  4OOK A;  2EA4 A;  1B59 A;  4RGZ 1;  1YVM A;  2GZ5 A;  1O0X A;  2HOW A;  2P9A A;  2BN7 A;  3PKE A;  3TAV A;  5FCH A;  3BIT A;  2GG3 A;  1WBQ A;  1B6A A;  1WL9 A;  2GG9 A;  2BWS A;  4FO8 A;  4U70 A;  3PKB A;  4U76 A;  5JI6 A;  4PNC A;  5CDL A;  2IW2 A;  4FLK A;  2GU4 A;  1QZY A;  5CE6 A;  2OAZ A;  4IPA A;  4ZNG A;  5CLS A;  4S01 A;  1JAW A;  2BWY A;  1R5G A;  4IDY A;  1WL6 A;  2B3L A;  2BHC A;  2GGC A;  5D6F A;  4EGE A;  1XNZ A;  1MAT A;  2P99 A;  2BH3 A;  3IU8 A;  4U73 A;  2BHB A;  2OKN A;  3ROR A;  1YW8 A; 
#chains in the Genus database with same CATH homology
 2DFI A;  3PKC A;  1C22 A;  4U1B A;  4U69 A;  4ZWU A;  1QXZ A;  1A16 A;  5E5B A;  4U6Z A;  4QR8 A;  4PV4 A;  3BIP A;  2BHD A;  4IKS A;  4IU6 A;  3CB5 A;  4FO7 A;  5CDV A;  2GG0 A;  3D27 A;  2BWX A;  1KQ9 A;  3BIQ A;  2Q94 A;  4MAT A;  4RZY A;  1YW9 A;  2P98 A;  2Q8K A;  4JUQ A;  2B3K A;  2BWW A;  2BWU A;  3PKA A;  4B28 A;  4KM3 A;  3Q6D A;  2Q96 A;  4FLJ A;  5FCF A;  1BOA A;  4U6C A;  2Q92 A;  3FM3 A;  1PV9 A;  1QXY A;  1N51 A;  1WN1 A;  3MR1 A;  1R58 A;  1YW7 A;  2V3X A;  3FMQ A;  2Q95 A;  4S2T P;  2GA2 A;  1M35 A;  1Y1N A;  2BWV A;  4A6W A;  3MAT A;  4S2R P;  2BHA A;  2BWT A;  4IF7 A;  4U71 A;  1CHM A;  1C24 A;  1YJ3 A;  2GU5 A;  2GU6 A;  2BB7 A;  2B3H A;  1W7V A;  4IKU A;  2NQ6 A;  2EVO A;  2GTX A;  5CNX A;  4A6V A;  3L24 A;  3IG4 A;  4RZZ A;  2V6C A;  2EA2 A;  1C21 A;  2G6P A;  2V3Z A;  2ADU A;  5D6E A;  2MAT A;  4U6W A;  1KQ0 A;  3TB5 A;  2NQ7 A;  3MX6 A;  1WLR A;  4FUK A;  3RVA A;  1BN5 A;  3IU9 A;  1XGO A;  2V3Y A;  5CDE A;  4FLI A;  3IU7 A;  1XGS A;  4ZWP A;  4U6E A;  4Z7M A;  1XGM A;  2GG5 A;  4IKT A;  4S00 A;  3S6B A;  5JFR A;  3PKD A;  1R5H A;  2GGB A;  3FMR A;  4IKR A;  2EVM A;  5JHU A;  4FKC A;  3CTZ A;  1C27 A;  2EVC A;  4ZWO A;  4R60 A;  5CIK A;  2Q93 A;  3L7G A;  1WKM A;  1WY2 A;  2GU7 A;  4HXX A;  4FLL A;  2GG8 A;  4U75 A;  1KP0 A;  4U6J A;  1C23 A;  2ZSG A;  2GG7 A;  4IEC A;  2GG2 A;  1QXW A;  1XGN A;  1W2M A;  3CB6 A;  4OOK A;  2EA4 A;  1B59 A;  4RGZ 1;  1YVM A;  2GZ5 A;  1O0X A;  2HOW A;  2P9A A;  2BN7 A;  3PKE A;  3TAV A;  5FCH A;  3BIT A;  2GG3 A;  1WBQ A;  1B6A A;  1WL9 A;  2GG9 A;  2BWS A;  4FO8 A;  4U70 A;  3PKB A;  4U76 A;  5JI6 A;  4PNC A;  5CDL A;  2IW2 A;  4FLK A;  2GU4 A;  1QZY A;  5CE6 A;  2OAZ A;  4IPA A;  4ZNG A;  5CLS A;  4S01 A;  1JAW A;  2BWY A;  1R5G A;  4IDY A;  1WL6 A;  2B3L A;  2BHC A;  2GGC A;  5D6F A;  4EGE A;  1XNZ A;  1MAT A;  2P99 A;  2BH3 A;  3IU8 A;  4U73 A;  2BHB A;  2OKN A;  3ROR A;  1YW8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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