1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
2Q94A 1C24A 1O0XA 3PKEA 1YVMA 2B3LA 4U69A 4IECA 2V3YA 2DFIA 1Y1NA 1QZYA 5CLSA 2BB7A 4S00A 4S2RP 4ZWUA 4U71A 1WN1A 4FO7A 4ZWPA 4R60A 1R58A 2Q93A 3MATA 4JUQA 1XGOA 2BH3A 4U70A 2GG3A 4S2TP 4IU6A 1KP0A 3FM3A 2EVOA 4ZNGA 5CDVA 1QXWA 4FLLA 4U6EA 1WL6A 4RZZA 2BWXA 2GG7A 2GG2A 1PV9A 1XGSA 2EA2A 3Q6DA 4RZYA 3FMQA 1WKMA 3IG4A 5D6FA 1W7VA 5D6EA 2GTXA 3PKDA 4FO8A 2V3ZA 1CHMA 2OAZA 3CB5A 4ZWOA 2EVCA 3L7GA 4IKSA 2BWVA 4IKUA 2MATA 2Q92A 4FLIA 1R5GA 4FKCA 1W2MA 5E5BA 5JFRA 2P98A 1QXZA 4U73A 2BWUA 2GG9A 2B3KA 2GZ5A 3FMRA 2OKNA 2BN7A 3PKBA 3TAVA 5JHUA 3IU8A 2GG5A 3CB6A 2BWYA 2GU4A 4FLJA 5CDLA 1BOAA 2ZSGA 1B59A 2BHCA 4IF7A 4B28A 2GG0A 2GU5A 1A16A 2GU6A 3D27A 3BIQA 1WBQA 4EGEA 2P99A 2BHDA 2GG8A 5CDEA 2V3XA 1BN5A 2NQ7A 2Q95A 4MATA 3L24A 4U6CA 2EVMA 2GGCA 5CE6A 1WL9A 4QR8A 1C21A 1KQ9A 1C27A 4KM3A 4RGZ1 4FLKA 4IDYA 4U75A 3BIPA 5FCFA 3IU7A 2V6CA 2GGBA 1WY2A 4U6ZA 2BHBA 2BHAA 2Q96A 1C22A 5FCHA 4PNCA 4FUKA 1YW9A 4IKTA 3PKAA 1YW7A 2ADUA 1R5HA 2GA2A 1JAWA 3IU9A 4S01A 5CIKA 2IW2A 4U6JA 1WLRA 1YJ3A 5JI6A 2BWWA 4U76A 2Q8KA 3MX6A 3RVAA 4U6WA 3PKCA 4PV4A 2P9AA 4HXXA 2G6PA 2EA4A 1YW8A 5CNXA 1B6AA 2NQ6A 3BITA 1KQ0A 2HOWA 1N51A 1C23A 4IKRA 2GU7A 1XGMA 3S6BA 4Z7MA 1XGNA 2BWTA 4U1BA 1QXYA 3RORA 4A6WA 2BWSA 4A6VA 1XNZA 4OOKA 3MR1A 1MATA 1M35A 4IPAA 3CTZA 3TB5A 2B3HA
chains in the Genus database with same CATH superfamily
2Q94A 1C24A 1O0XA 3PKEA 1YVMA 2B3LA 4U69A 4IECA 2V3YA 2DFIA 1Y1NA 1QZYA 5CLSA 2BB7A 4S00A 4S2RP 4ZWUA 4U71A 1WN1A 4FO7A 4ZWPA 4R60A 1R58A 2Q93A 3MATA 4JUQA 1XGOA 2BH3A 4U70A 2GG3A 4S2TP 4IU6A 1KP0A 3FM3A 2EVOA 4ZNGA 5CDVA 1QXWA 4FLLA 4U6EA 1WL6A 4RZZA 2BWXA 2GG7A 2GG2A 1PV9A 1XGSA 2EA2A 3Q6DA 4RZYA 3FMQA 1WKMA 3IG4A 5D6FA 1W7VA 5D6EA 2GTXA 3PKDA 4FO8A 2V3ZA 1CHMA 2OAZA 3CB5A 4ZWOA 2EVCA 3L7GA 4IKSA 2BWVA 4IKUA 2MATA 2Q92A 4FLIA 1R5GA 4FKCA 1W2MA 5E5BA 5JFRA 2P98A 1QXZA 4U73A 2BWUA 2GG9A 2B3KA 2GZ5A 3FMRA 2OKNA 2BN7A 3PKBA 3TAVA 5JHUA 3IU8A 2GG5A 3CB6A 2BWYA 2GU4A 4FLJA 5CDLA 1BOAA 2ZSGA 1B59A 2BHCA 4IF7A 4B28A 2GG0A 2GU5A 1A16A 2GU6A 3D27A 3BIQA 1WBQA 4EGEA 2P99A 2BHDA 2GG8A 5CDEA 2V3XA 1BN5A 2NQ7A 2Q95A 4MATA 3L24A 4U6CA 2EVMA 2GGCA 5CE6A 1WL9A 4QR8A 1C21A 1KQ9A 1C27A 4KM3A 4RGZ1 4FLKA 4IDYA 4U75A 3BIPA 5FCFA 3IU7A 2V6CA 2GGBA 1WY2A 4U6ZA 2BHBA 2BHAA 2Q96A 1C22A 5FCHA 4PNCA 4FUKA 1YW9A 4IKTA 3PKAA 1YW7A 2ADUA 1R5HA 2GA2A 1JAWA 3IU9A 4S01A 5CIKA 2IW2A 4U6JA 1WLRA 1YJ3A 5JI6A 2BWWA 4U76A 2Q8KA 3MX6A 3RVAA 4U6WA 3PKCA 4PV4A 2P9AA 4HXXA 2G6PA 2EA4A 1YW8A 5CNXA 1B6AA 2NQ6A 3BITA 1KQ0A 2HOWA 1N51A 1C23A 4IKRA 2GU7A 1XGMA 3S6BA 4Z7MA 1XGNA 2BWTA 4U1BA 1QXYA 3RORA 4A6WA 2BWSA 4A6VA 1XNZA 4OOKA 3MR1A 1MATA 1M35A 4IPAA 3CTZA 3TB5A 2B3HA
chains in the Genus database with same CATH topology
2Q94A 1C24A 1O0XA 3PKEA 1YVMA 2B3LA 4U69A 4IECA 2V3YA 2DFIA 1Y1NA 1QZYA 5CLSA 2BB7A 4S00A 4S2RP 4ZWUA 4U71A 1WN1A 4FO7A 4ZWPA 4R60A 1R58A 2Q93A 3MATA 4JUQA 1XGOA 2BH3A 4U70A 2GG3A 4S2TP 4IU6A 1KP0A 3FM3A 2EVOA 4ZNGA 5CDVA 1QXWA 4FLLA 4U6EA 1WL6A 4RZZA 2BWXA 2GG7A 2GG2A 1PV9A 1XGSA 2EA2A 3Q6DA 4RZYA 3FMQA 1WKMA 3IG4A 5D6FA 1W7VA 5D6EA 2GTXA 3PKDA 4FO8A 2V3ZA 1CHMA 2OAZA 3CB5A 4ZWOA 2EVCA 3L7GA 4IKSA 2BWVA 4IKUA 2MATA 2Q92A 4FLIA 1R5GA 4FKCA 1W2MA 5E5BA 5JFRA 2P98A 1QXZA 4U73A 2BWUA 2GG9A 2B3KA 2GZ5A 3FMRA 2OKNA 2BN7A 3PKBA 3TAVA 5JHUA 3IU8A 2GG5A 3CB6A 2BWYA 2GU4A 4FLJA 5CDLA 1BOAA 2ZSGA 1B59A 2BHCA 4IF7A 4B28A 2GG0A 2GU5A 1A16A 2GU6A 3D27A 3BIQA 1WBQA 4EGEA 2P99A 2BHDA 2GG8A 5CDEA 2V3XA 1BN5A 2NQ7A 2Q95A 4MATA 3L24A 4U6CA 2EVMA 2GGCA 5CE6A 1WL9A 4QR8A 1C21A 1KQ9A 1C27A 4KM3A 4RGZ1 4FLKA 4IDYA 4U75A 3BIPA 5FCFA 3IU7A 2V6CA 2GGBA 1WY2A 4U6ZA 2BHBA 2BHAA 2Q96A 1C22A 5FCHA 4PNCA 4FUKA 1YW9A 4IKTA 3PKAA 1YW7A 2ADUA 1R5HA 2GA2A 1JAWA 3IU9A 4S01A 5CIKA 2IW2A 4U6JA 1WLRA 1YJ3A 5JI6A 2BWWA 4U76A 2Q8KA 3MX6A 3RVAA 4U6WA 3PKCA 4PV4A 2P9AA 4HXXA 2G6PA 2EA4A 1YW8A 5CNXA 1B6AA 2NQ6A 3BITA 1KQ0A 2HOWA 1N51A 1C23A 4IKRA 2GU7A 1XGMA 3S6BA 4Z7MA 1XGNA 2BWTA 4U1BA 1QXYA 3RORA 4A6WA 2BWSA 4A6VA 1XNZA 4OOKA 3MR1A 1MATA 1M35A 4IPAA 3CTZA 3TB5A 2B3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q94 A;  1C24 A;  1O0X A;  3PKE A;  1YVM A;  2B3L A;  4U69 A;  4IEC A;  2V3Y A;  2DFI A;  1Y1N A;  1QZY A;  5CLS A;  2BB7 A;  4S00 A;  4S2R P;  4ZWU A;  4U71 A;  1WN1 A;  4FO7 A;  4ZWP A;  4R60 A;  1R58 A;  2Q93 A;  3MAT A;  4JUQ A;  1XGO A;  2BH3 A;  4U70 A;  2GG3 A;  4S2T P;  4IU6 A;  1KP0 A;  3FM3 A;  2EVO A;  4ZNG A;  5CDV A;  1QXW A;  4FLL A;  4U6E A;  1WL6 A;  4RZZ A;  2BWX A;  2GG7 A;  2GG2 A;  1PV9 A;  1XGS A;  2EA2 A;  3Q6D A;  4RZY A;  3FMQ A;  1WKM A;  3IG4 A;  5D6F A;  1W7V A;  5D6E A;  2GTX A;  3PKD A;  4FO8 A;  2V3Z A;  1CHM A;  2OAZ A;  3CB5 A;  4ZWO A;  2EVC A;  3L7G A;  4IKS A;  2BWV A;  4IKU A;  2MAT A;  2Q92 A;  4FLI A;  1R5G A;  4FKC A;  1W2M A;  5E5B A;  5JFR A;  2P98 A;  1QXZ A;  4U73 A;  2BWU A;  2GG9 A;  2B3K A;  2GZ5 A;  3FMR A;  2OKN A;  2BN7 A;  3PKB A;  3TAV A;  5JHU A;  3IU8 A;  2GG5 A;  3CB6 A;  2BWY A;  2GU4 A;  4FLJ A;  5CDL A;  1BOA A;  2ZSG A;  1B59 A;  2BHC A;  4IF7 A;  4B28 A;  2GG0 A;  2GU5 A;  1A16 A;  2GU6 A;  3D27 A;  3BIQ A;  1WBQ A;  4EGE A;  2P99 A;  2BHD A;  2GG8 A;  5CDE A;  2V3X A;  1BN5 A;  2NQ7 A;  2Q95 A;  4MAT A;  3L24 A;  4U6C A;  2EVM A;  2GGC A;  5CE6 A;  1WL9 A;  4QR8 A;  1C21 A;  1KQ9 A;  1C27 A;  4KM3 A;  4RGZ 1;  4FLK A;  4IDY A;  4U75 A;  3BIP A;  5FCF A;  3IU7 A;  2V6C A;  2GGB A;  1WY2 A;  4U6Z A;  2BHB A;  2BHA A;  2Q96 A;  1C22 A;  5FCH A;  4PNC A;  4FUK A;  1YW9 A;  4IKT A;  3PKA A;  1YW7 A;  2ADU A;  1R5H A;  2GA2 A;  1JAW A;  3IU9 A;  4S01 A;  5CIK A;  2IW2 A;  4U6J A;  1WLR A;  1YJ3 A;  5JI6 A;  2BWW A;  4U76 A;  2Q8K A;  3MX6 A;  3RVA A;  4U6W A;  3PKC A;  4PV4 A;  2P9A A;  4HXX A;  2G6P A;  2EA4 A;  1YW8 A;  5CNX A;  1B6A A;  2NQ6 A;  3BIT A;  1KQ0 A;  2HOW A;  1N51 A;  1C23 A;  4IKR A;  2GU7 A;  1XGM A;  3S6B A;  4Z7M A;  1XGN A;  2BWT A;  4U1B A;  1QXY A;  3ROR A;  4A6W A;  2BWS A;  4A6V A;  1XNZ A;  4OOK A;  3MR1 A;  1MAT A;  1M35 A;  4IPA A;  3CTZ A;  3TB5 A;  2B3H A; 
#chains in the Genus database with same CATH topology
 2Q94 A;  1C24 A;  1O0X A;  3PKE A;  1YVM A;  2B3L A;  4U69 A;  4IEC A;  2V3Y A;  2DFI A;  1Y1N A;  1QZY A;  5CLS A;  2BB7 A;  4S00 A;  4S2R P;  4ZWU A;  4U71 A;  1WN1 A;  4FO7 A;  4ZWP A;  4R60 A;  1R58 A;  2Q93 A;  3MAT A;  4JUQ A;  1XGO A;  2BH3 A;  4U70 A;  2GG3 A;  4S2T P;  4IU6 A;  1KP0 A;  3FM3 A;  2EVO A;  4ZNG A;  5CDV A;  1QXW A;  4FLL A;  4U6E A;  1WL6 A;  4RZZ A;  2BWX A;  2GG7 A;  2GG2 A;  1PV9 A;  1XGS A;  2EA2 A;  3Q6D A;  4RZY A;  3FMQ A;  1WKM A;  3IG4 A;  5D6F A;  1W7V A;  5D6E A;  2GTX A;  3PKD A;  4FO8 A;  2V3Z A;  1CHM A;  2OAZ A;  3CB5 A;  4ZWO A;  2EVC A;  3L7G A;  4IKS A;  2BWV A;  4IKU A;  2MAT A;  2Q92 A;  4FLI A;  1R5G A;  4FKC A;  1W2M A;  5E5B A;  5JFR A;  2P98 A;  1QXZ A;  4U73 A;  2BWU A;  2GG9 A;  2B3K A;  2GZ5 A;  3FMR A;  2OKN A;  2BN7 A;  3PKB A;  3TAV A;  5JHU A;  3IU8 A;  2GG5 A;  3CB6 A;  2BWY A;  2GU4 A;  4FLJ A;  5CDL A;  1BOA A;  2ZSG A;  1B59 A;  2BHC A;  4IF7 A;  4B28 A;  2GG0 A;  2GU5 A;  1A16 A;  2GU6 A;  3D27 A;  3BIQ A;  1WBQ A;  4EGE A;  2P99 A;  2BHD A;  2GG8 A;  5CDE A;  2V3X A;  1BN5 A;  2NQ7 A;  2Q95 A;  4MAT A;  3L24 A;  4U6C A;  2EVM A;  2GGC A;  5CE6 A;  1WL9 A;  4QR8 A;  1C21 A;  1KQ9 A;  1C27 A;  4KM3 A;  4RGZ 1;  4FLK A;  4IDY A;  4U75 A;  3BIP A;  5FCF A;  3IU7 A;  2V6C A;  2GGB A;  1WY2 A;  4U6Z A;  2BHB A;  2BHA A;  2Q96 A;  1C22 A;  5FCH A;  4PNC A;  4FUK A;  1YW9 A;  4IKT A;  3PKA A;  1YW7 A;  2ADU A;  1R5H A;  2GA2 A;  1JAW A;  3IU9 A;  4S01 A;  5CIK A;  2IW2 A;  4U6J A;  1WLR A;  1YJ3 A;  5JI6 A;  2BWW A;  4U76 A;  2Q8K A;  3MX6 A;  3RVA A;  4U6W A;  3PKC A;  4PV4 A;  2P9A A;  4HXX A;  2G6P A;  2EA4 A;  1YW8 A;  5CNX A;  1B6A A;  2NQ6 A;  3BIT A;  1KQ0 A;  2HOW A;  1N51 A;  1C23 A;  4IKR A;  2GU7 A;  1XGM A;  3S6B A;  4Z7M A;  1XGN A;  2BWT A;  4U1B A;  1QXY A;  3ROR A;  4A6W A;  2BWS A;  4A6V A;  1XNZ A;  4OOK A;  3MR1 A;  1MAT A;  1M35 A;  4IPA A;  3CTZ A;  3TB5 A;  2B3H A; 
#chains in the Genus database with same CATH homology
 2Q94 A;  1C24 A;  1O0X A;  3PKE A;  1YVM A;  2B3L A;  4U69 A;  4IEC A;  2V3Y A;  2DFI A;  1Y1N A;  1QZY A;  5CLS A;  2BB7 A;  4S00 A;  4S2R P;  4ZWU A;  4U71 A;  1WN1 A;  4FO7 A;  4ZWP A;  4R60 A;  1R58 A;  2Q93 A;  3MAT A;  4JUQ A;  1XGO A;  2BH3 A;  4U70 A;  2GG3 A;  4S2T P;  4IU6 A;  1KP0 A;  3FM3 A;  2EVO A;  4ZNG A;  5CDV A;  1QXW A;  4FLL A;  4U6E A;  1WL6 A;  4RZZ A;  2BWX A;  2GG7 A;  2GG2 A;  1PV9 A;  1XGS A;  2EA2 A;  3Q6D A;  4RZY A;  3FMQ A;  1WKM A;  3IG4 A;  5D6F A;  1W7V A;  5D6E A;  2GTX A;  3PKD A;  4FO8 A;  2V3Z A;  1CHM A;  2OAZ A;  3CB5 A;  4ZWO A;  2EVC A;  3L7G A;  4IKS A;  2BWV A;  4IKU A;  2MAT A;  2Q92 A;  4FLI A;  1R5G A;  4FKC A;  1W2M A;  5E5B A;  5JFR A;  2P98 A;  1QXZ A;  4U73 A;  2BWU A;  2GG9 A;  2B3K A;  2GZ5 A;  3FMR A;  2OKN A;  2BN7 A;  3PKB A;  3TAV A;  5JHU A;  3IU8 A;  2GG5 A;  3CB6 A;  2BWY A;  2GU4 A;  4FLJ A;  5CDL A;  1BOA A;  2ZSG A;  1B59 A;  2BHC A;  4IF7 A;  4B28 A;  2GG0 A;  2GU5 A;  1A16 A;  2GU6 A;  3D27 A;  3BIQ A;  1WBQ A;  4EGE A;  2P99 A;  2BHD A;  2GG8 A;  5CDE A;  2V3X A;  1BN5 A;  2NQ7 A;  2Q95 A;  4MAT A;  3L24 A;  4U6C A;  2EVM A;  2GGC A;  5CE6 A;  1WL9 A;  4QR8 A;  1C21 A;  1KQ9 A;  1C27 A;  4KM3 A;  4RGZ 1;  4FLK A;  4IDY A;  4U75 A;  3BIP A;  5FCF A;  3IU7 A;  2V6C A;  2GGB A;  1WY2 A;  4U6Z A;  2BHB A;  2BHA A;  2Q96 A;  1C22 A;  5FCH A;  4PNC A;  4FUK A;  1YW9 A;  4IKT A;  3PKA A;  1YW7 A;  2ADU A;  1R5H A;  2GA2 A;  1JAW A;  3IU9 A;  4S01 A;  5CIK A;  2IW2 A;  4U6J A;  1WLR A;  1YJ3 A;  5JI6 A;  2BWW A;  4U76 A;  2Q8K A;  3MX6 A;  3RVA A;  4U6W A;  3PKC A;  4PV4 A;  2P9A A;  4HXX A;  2G6P A;  2EA4 A;  1YW8 A;  5CNX A;  1B6A A;  2NQ6 A;  3BIT A;  1KQ0 A;  2HOW A;  1N51 A;  1C23 A;  4IKR A;  2GU7 A;  1XGM A;  3S6B A;  4Z7M A;  1XGN A;  2BWT A;  4U1B A;  1QXY A;  3ROR A;  4A6W A;  2BWS A;  4A6V A;  1XNZ A;  4OOK A;  3MR1 A;  1MAT A;  1M35 A;  4IPA A;  3CTZ A;  3TB5 A;  2B3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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