1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
3BITA 5CNXA 4ZWUA 1XGNA 2GA2A 2BWVA 4FLJA 1XNZA 4QR8A 5JFRA 1M35A 1YW8A 2BHCA 5D6FA 2EA2A 3CB5A 3BIPA 1CHMA 2BWXA 2BB7A 3PKAA 4S00A 3PKBA 4IKTA 3L24A 4U6JA 4PV4A 4IU6A 2Q8KA 1WN1A 2GG7A 1QXZA 4IKSA 4FLKA 4RZYA 3TB5A 1WY2A 5CE6A 3S6BA 4FLLA 1WBQA 3PKCA 4U6EA 2GG8A 2OKNA 1YW7A 1W7VA 1WKMA 4S2TP 2BHDA 5FCFA 2BN7A 4U71A 1QZYA 2B3LA 2IW2A 2DFIA 2NQ6A 3RORA 1N51A 2P9AA 1Y1NA 1YW9A 3FMRA 4OOKA 2OAZA 2P98A 2Q96A 2NQ7A 4U75A 3CB6A 2GU7A 3Q6DA 4ZNGA 1BOAA 1B6AA 2BHAA 2GU4A 3CTZA 4PNCA 4U76A 1WL6A 2BH3A 4MATA 3MR1A 5CIKA 1KP0A 1KQ0A 1YJ3A 4JUQA 4KM3A 1R5HA 2GU6A 2Q95A 3IG4A 4FLIA 5CDLA 2GU5A 4U6WA 1R5GA 2MATA 1O0XA 2EVMA 1PV9A 2GGCA 4ZWPA 2V3YA 3IU9A 5FCHA 1QXWA 4U1BA 2V3ZA 4IKRA 4U6CA 1XGMA 2GGBA 3IU7A 1W2MA 1YVMA 3PKEA 4U73A 1JAWA 2BWYA 2B3HA 2BHBA 4R60A 2GG0A 2EVCA 2ZSGA 1R58A 4RGZ1 1WLRA 1XGOA 1C23A 4FKCA 1QXYA 4U70A 5CLSA 3MATA 4IKUA 4FO7A 3D27A 1C22A 2EVOA 2Q93A 2B3KA 2V6CA 2GTXA 2P99A 1A16A 5CDEA 2GZ5A 2V3XA 4IECA 2G6PA 4IPAA 4A6VA 1WL9A 4U6ZA 3RVAA 2Q94A 4S2RP 2EA4A 1C21A 4ZWOA 1BN5A 4U69A 3L7GA 5D6EA 4FO8A 2HOWA 3BIQA 3FM3A 4IDYA 5JI6A 3IU8A 2BWTA 4EGEA 4HXXA 2BWSA 4RZZA 3FMQA 1C24A 4FUKA 1B59A 2BWUA 1KQ9A 1MATA 2BWWA 2GG3A 4S01A 4A6WA 3PKDA 2Q92A 3TAVA 4Z7MA 2GG9A 2GG5A 1XGSA 2ADUA 1C27A 5CDVA 5JHUA 3MX6A 4IF7A 5E5BA 4B28A 2GG2A
chains in the Genus database with same CATH superfamily
3BITA 5CNXA 4ZWUA 1XGNA 2GA2A 2BWVA 4FLJA 1XNZA 4QR8A 5JFRA 1M35A 1YW8A 2BHCA 5D6FA 2EA2A 3CB5A 3BIPA 1CHMA 2BWXA 2BB7A 3PKAA 4S00A 3PKBA 4IKTA 3L24A 4U6JA 4PV4A 4IU6A 2Q8KA 1WN1A 2GG7A 1QXZA 4IKSA 4FLKA 4RZYA 3TB5A 1WY2A 5CE6A 3S6BA 4FLLA 1WBQA 3PKCA 4U6EA 2GG8A 2OKNA 1YW7A 1W7VA 1WKMA 4S2TP 2BHDA 5FCFA 2BN7A 4U71A 1QZYA 2B3LA 2IW2A 2DFIA 2NQ6A 3RORA 1N51A 2P9AA 1Y1NA 1YW9A 3FMRA 4OOKA 2OAZA 2P98A 2Q96A 2NQ7A 4U75A 3CB6A 2GU7A 3Q6DA 4ZNGA 1BOAA 1B6AA 2BHAA 2GU4A 3CTZA 4PNCA 4U76A 1WL6A 2BH3A 4MATA 3MR1A 5CIKA 1KP0A 1KQ0A 1YJ3A 4JUQA 4KM3A 1R5HA 2GU6A 2Q95A 3IG4A 4FLIA 5CDLA 2GU5A 4U6WA 1R5GA 2MATA 1O0XA 2EVMA 1PV9A 2GGCA 4ZWPA 2V3YA 3IU9A 5FCHA 1QXWA 4U1BA 2V3ZA 4IKRA 4U6CA 1XGMA 2GGBA 3IU7A 1W2MA 1YVMA 3PKEA 4U73A 1JAWA 2BWYA 2B3HA 2BHBA 4R60A 2GG0A 2EVCA 2ZSGA 1R58A 4RGZ1 1WLRA 1XGOA 1C23A 4FKCA 1QXYA 4U70A 5CLSA 3MATA 4IKUA 4FO7A 3D27A 1C22A 2EVOA 2Q93A 2B3KA 2V6CA 2GTXA 2P99A 1A16A 5CDEA 2GZ5A 2V3XA 4IECA 2G6PA 4IPAA 4A6VA 1WL9A 4U6ZA 3RVAA 2Q94A 4S2RP 2EA4A 1C21A 4ZWOA 1BN5A 4U69A 3L7GA 5D6EA 4FO8A 2HOWA 3BIQA 3FM3A 4IDYA 5JI6A 3IU8A 2BWTA 4EGEA 4HXXA 2BWSA 4RZZA 3FMQA 1C24A 4FUKA 1B59A 2BWUA 1KQ9A 1MATA 2BWWA 2GG3A 4S01A 4A6WA 3PKDA 2Q92A 3TAVA 4Z7MA 2GG9A 2GG5A 1XGSA 2ADUA 1C27A 5CDVA 5JHUA 3MX6A 4IF7A 5E5BA 4B28A 2GG2A
chains in the Genus database with same CATH topology
3BITA 5CNXA 4ZWUA 1XGNA 2GA2A 2BWVA 4FLJA 1XNZA 4QR8A 5JFRA 1M35A 1YW8A 2BHCA 5D6FA 2EA2A 3CB5A 3BIPA 1CHMA 2BWXA 2BB7A 3PKAA 4S00A 3PKBA 4IKTA 3L24A 4U6JA 4PV4A 4IU6A 2Q8KA 1WN1A 2GG7A 1QXZA 4IKSA 4FLKA 4RZYA 3TB5A 1WY2A 5CE6A 3S6BA 4FLLA 1WBQA 3PKCA 4U6EA 2GG8A 2OKNA 1YW7A 1W7VA 1WKMA 4S2TP 2BHDA 5FCFA 2BN7A 4U71A 1QZYA 2B3LA 2IW2A 2DFIA 2NQ6A 3RORA 1N51A 2P9AA 1Y1NA 1YW9A 3FMRA 4OOKA 2OAZA 2P98A 2Q96A 2NQ7A 4U75A 3CB6A 2GU7A 3Q6DA 4ZNGA 1BOAA 1B6AA 2BHAA 2GU4A 3CTZA 4PNCA 4U76A 1WL6A 2BH3A 4MATA 3MR1A 5CIKA 1KP0A 1KQ0A 1YJ3A 4JUQA 4KM3A 1R5HA 2GU6A 2Q95A 3IG4A 4FLIA 5CDLA 2GU5A 4U6WA 1R5GA 2MATA 1O0XA 2EVMA 1PV9A 2GGCA 4ZWPA 2V3YA 3IU9A 5FCHA 1QXWA 4U1BA 2V3ZA 4IKRA 4U6CA 1XGMA 2GGBA 3IU7A 1W2MA 1YVMA 3PKEA 4U73A 1JAWA 2BWYA 2B3HA 2BHBA 4R60A 2GG0A 2EVCA 2ZSGA 1R58A 4RGZ1 1WLRA 1XGOA 1C23A 4FKCA 1QXYA 4U70A 5CLSA 3MATA 4IKUA 4FO7A 3D27A 1C22A 2EVOA 2Q93A 2B3KA 2V6CA 2GTXA 2P99A 1A16A 5CDEA 2GZ5A 2V3XA 4IECA 2G6PA 4IPAA 4A6VA 1WL9A 4U6ZA 3RVAA 2Q94A 4S2RP 2EA4A 1C21A 4ZWOA 1BN5A 4U69A 3L7GA 5D6EA 4FO8A 2HOWA 3BIQA 3FM3A 4IDYA 5JI6A 3IU8A 2BWTA 4EGEA 4HXXA 2BWSA 4RZZA 3FMQA 1C24A 4FUKA 1B59A 2BWUA 1KQ9A 1MATA 2BWWA 2GG3A 4S01A 4A6WA 3PKDA 2Q92A 3TAVA 4Z7MA 2GG9A 2GG5A 1XGSA 2ADUA 1C27A 5CDVA 5JHUA 3MX6A 4IF7A 5E5BA 4B28A 2GG2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BIT A;  5CNX A;  4ZWU A;  1XGN A;  2GA2 A;  2BWV A;  4FLJ A;  1XNZ A;  4QR8 A;  5JFR A;  1M35 A;  1YW8 A;  2BHC A;  5D6F A;  2EA2 A;  3CB5 A;  3BIP A;  1CHM A;  2BWX A;  2BB7 A;  3PKA A;  4S00 A;  3PKB A;  4IKT A;  3L24 A;  4U6J A;  4PV4 A;  4IU6 A;  2Q8K A;  1WN1 A;  2GG7 A;  1QXZ A;  4IKS A;  4FLK A;  4RZY A;  3TB5 A;  1WY2 A;  5CE6 A;  3S6B A;  4FLL A;  1WBQ A;  3PKC A;  4U6E A;  2GG8 A;  2OKN A;  1YW7 A;  1W7V A;  1WKM A;  4S2T P;  2BHD A;  5FCF A;  2BN7 A;  4U71 A;  1QZY A;  2B3L A;  2IW2 A;  2DFI A;  2NQ6 A;  3ROR A;  1N51 A;  2P9A A;  1Y1N A;  1YW9 A;  3FMR A;  4OOK A;  2OAZ A;  2P98 A;  2Q96 A;  2NQ7 A;  4U75 A;  3CB6 A;  2GU7 A;  3Q6D A;  4ZNG A;  1BOA A;  1B6A A;  2BHA A;  2GU4 A;  3CTZ A;  4PNC A;  4U76 A;  1WL6 A;  2BH3 A;  4MAT A;  3MR1 A;  5CIK A;  1KP0 A;  1KQ0 A;  1YJ3 A;  4JUQ A;  4KM3 A;  1R5H A;  2GU6 A;  2Q95 A;  3IG4 A;  4FLI A;  5CDL A;  2GU5 A;  4U6W A;  1R5G A;  2MAT A;  1O0X A;  2EVM A;  1PV9 A;  2GGC A;  4ZWP A;  2V3Y A;  3IU9 A;  5FCH A;  1QXW A;  4U1B A;  2V3Z A;  4IKR A;  4U6C A;  1XGM A;  2GGB A;  3IU7 A;  1W2M A;  1YVM A;  3PKE A;  4U73 A;  1JAW A;  2BWY A;  2B3H A;  2BHB A;  4R60 A;  2GG0 A;  2EVC A;  2ZSG A;  1R58 A;  4RGZ 1;  1WLR A;  1XGO A;  1C23 A;  4FKC A;  1QXY A;  4U70 A;  5CLS A;  3MAT A;  4IKU A;  4FO7 A;  3D27 A;  1C22 A;  2EVO A;  2Q93 A;  2B3K A;  2V6C A;  2GTX A;  2P99 A;  1A16 A;  5CDE A;  2GZ5 A;  2V3X A;  4IEC A;  2G6P A;  4IPA A;  4A6V A;  1WL9 A;  4U6Z A;  3RVA A;  2Q94 A;  4S2R P;  2EA4 A;  1C21 A;  4ZWO A;  1BN5 A;  4U69 A;  3L7G A;  5D6E A;  4FO8 A;  2HOW A;  3BIQ A;  3FM3 A;  4IDY A;  5JI6 A;  3IU8 A;  2BWT A;  4EGE A;  4HXX A;  2BWS A;  4RZZ A;  3FMQ A;  1C24 A;  4FUK A;  1B59 A;  2BWU A;  1KQ9 A;  1MAT A;  2BWW A;  2GG3 A;  4S01 A;  4A6W A;  3PKD A;  2Q92 A;  3TAV A;  4Z7M A;  2GG9 A;  2GG5 A;  1XGS A;  2ADU A;  1C27 A;  5CDV A;  5JHU A;  3MX6 A;  4IF7 A;  5E5B A;  4B28 A;  2GG2 A; 
#chains in the Genus database with same CATH topology
 3BIT A;  5CNX A;  4ZWU A;  1XGN A;  2GA2 A;  2BWV A;  4FLJ A;  1XNZ A;  4QR8 A;  5JFR A;  1M35 A;  1YW8 A;  2BHC A;  5D6F A;  2EA2 A;  3CB5 A;  3BIP A;  1CHM A;  2BWX A;  2BB7 A;  3PKA A;  4S00 A;  3PKB A;  4IKT A;  3L24 A;  4U6J A;  4PV4 A;  4IU6 A;  2Q8K A;  1WN1 A;  2GG7 A;  1QXZ A;  4IKS A;  4FLK A;  4RZY A;  3TB5 A;  1WY2 A;  5CE6 A;  3S6B A;  4FLL A;  1WBQ A;  3PKC A;  4U6E A;  2GG8 A;  2OKN A;  1YW7 A;  1W7V A;  1WKM A;  4S2T P;  2BHD A;  5FCF A;  2BN7 A;  4U71 A;  1QZY A;  2B3L A;  2IW2 A;  2DFI A;  2NQ6 A;  3ROR A;  1N51 A;  2P9A A;  1Y1N A;  1YW9 A;  3FMR A;  4OOK A;  2OAZ A;  2P98 A;  2Q96 A;  2NQ7 A;  4U75 A;  3CB6 A;  2GU7 A;  3Q6D A;  4ZNG A;  1BOA A;  1B6A A;  2BHA A;  2GU4 A;  3CTZ A;  4PNC A;  4U76 A;  1WL6 A;  2BH3 A;  4MAT A;  3MR1 A;  5CIK A;  1KP0 A;  1KQ0 A;  1YJ3 A;  4JUQ A;  4KM3 A;  1R5H A;  2GU6 A;  2Q95 A;  3IG4 A;  4FLI A;  5CDL A;  2GU5 A;  4U6W A;  1R5G A;  2MAT A;  1O0X A;  2EVM A;  1PV9 A;  2GGC A;  4ZWP A;  2V3Y A;  3IU9 A;  5FCH A;  1QXW A;  4U1B A;  2V3Z A;  4IKR A;  4U6C A;  1XGM A;  2GGB A;  3IU7 A;  1W2M A;  1YVM A;  3PKE A;  4U73 A;  1JAW A;  2BWY A;  2B3H A;  2BHB A;  4R60 A;  2GG0 A;  2EVC A;  2ZSG A;  1R58 A;  4RGZ 1;  1WLR A;  1XGO A;  1C23 A;  4FKC A;  1QXY A;  4U70 A;  5CLS A;  3MAT A;  4IKU A;  4FO7 A;  3D27 A;  1C22 A;  2EVO A;  2Q93 A;  2B3K A;  2V6C A;  2GTX A;  2P99 A;  1A16 A;  5CDE A;  2GZ5 A;  2V3X A;  4IEC A;  2G6P A;  4IPA A;  4A6V A;  1WL9 A;  4U6Z A;  3RVA A;  2Q94 A;  4S2R P;  2EA4 A;  1C21 A;  4ZWO A;  1BN5 A;  4U69 A;  3L7G A;  5D6E A;  4FO8 A;  2HOW A;  3BIQ A;  3FM3 A;  4IDY A;  5JI6 A;  3IU8 A;  2BWT A;  4EGE A;  4HXX A;  2BWS A;  4RZZ A;  3FMQ A;  1C24 A;  4FUK A;  1B59 A;  2BWU A;  1KQ9 A;  1MAT A;  2BWW A;  2GG3 A;  4S01 A;  4A6W A;  3PKD A;  2Q92 A;  3TAV A;  4Z7M A;  2GG9 A;  2GG5 A;  1XGS A;  2ADU A;  1C27 A;  5CDV A;  5JHU A;  3MX6 A;  4IF7 A;  5E5B A;  4B28 A;  2GG2 A; 
#chains in the Genus database with same CATH homology
 3BIT A;  5CNX A;  4ZWU A;  1XGN A;  2GA2 A;  2BWV A;  4FLJ A;  1XNZ A;  4QR8 A;  5JFR A;  1M35 A;  1YW8 A;  2BHC A;  5D6F A;  2EA2 A;  3CB5 A;  3BIP A;  1CHM A;  2BWX A;  2BB7 A;  3PKA A;  4S00 A;  3PKB A;  4IKT A;  3L24 A;  4U6J A;  4PV4 A;  4IU6 A;  2Q8K A;  1WN1 A;  2GG7 A;  1QXZ A;  4IKS A;  4FLK A;  4RZY A;  3TB5 A;  1WY2 A;  5CE6 A;  3S6B A;  4FLL A;  1WBQ A;  3PKC A;  4U6E A;  2GG8 A;  2OKN A;  1YW7 A;  1W7V A;  1WKM A;  4S2T P;  2BHD A;  5FCF A;  2BN7 A;  4U71 A;  1QZY A;  2B3L A;  2IW2 A;  2DFI A;  2NQ6 A;  3ROR A;  1N51 A;  2P9A A;  1Y1N A;  1YW9 A;  3FMR A;  4OOK A;  2OAZ A;  2P98 A;  2Q96 A;  2NQ7 A;  4U75 A;  3CB6 A;  2GU7 A;  3Q6D A;  4ZNG A;  1BOA A;  1B6A A;  2BHA A;  2GU4 A;  3CTZ A;  4PNC A;  4U76 A;  1WL6 A;  2BH3 A;  4MAT A;  3MR1 A;  5CIK A;  1KP0 A;  1KQ0 A;  1YJ3 A;  4JUQ A;  4KM3 A;  1R5H A;  2GU6 A;  2Q95 A;  3IG4 A;  4FLI A;  5CDL A;  2GU5 A;  4U6W A;  1R5G A;  2MAT A;  1O0X A;  2EVM A;  1PV9 A;  2GGC A;  4ZWP A;  2V3Y A;  3IU9 A;  5FCH A;  1QXW A;  4U1B A;  2V3Z A;  4IKR A;  4U6C A;  1XGM A;  2GGB A;  3IU7 A;  1W2M A;  1YVM A;  3PKE A;  4U73 A;  1JAW A;  2BWY A;  2B3H A;  2BHB A;  4R60 A;  2GG0 A;  2EVC A;  2ZSG A;  1R58 A;  4RGZ 1;  1WLR A;  1XGO A;  1C23 A;  4FKC A;  1QXY A;  4U70 A;  5CLS A;  3MAT A;  4IKU A;  4FO7 A;  3D27 A;  1C22 A;  2EVO A;  2Q93 A;  2B3K A;  2V6C A;  2GTX A;  2P99 A;  1A16 A;  5CDE A;  2GZ5 A;  2V3X A;  4IEC A;  2G6P A;  4IPA A;  4A6V A;  1WL9 A;  4U6Z A;  3RVA A;  2Q94 A;  4S2R P;  2EA4 A;  1C21 A;  4ZWO A;  1BN5 A;  4U69 A;  3L7G A;  5D6E A;  4FO8 A;  2HOW A;  3BIQ A;  3FM3 A;  4IDY A;  5JI6 A;  3IU8 A;  2BWT A;  4EGE A;  4HXX A;  2BWS A;  4RZZ A;  3FMQ A;  1C24 A;  4FUK A;  1B59 A;  2BWU A;  1KQ9 A;  1MAT A;  2BWW A;  2GG3 A;  4S01 A;  4A6W A;  3PKD A;  2Q92 A;  3TAV A;  4Z7M A;  2GG9 A;  2GG5 A;  1XGS A;  2ADU A;  1C27 A;  5CDV A;  5JHU A;  3MX6 A;  4IF7 A;  5E5B A;  4B28 A;  2GG2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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