1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
2EVCA 1YW8A 4U69A 4ZNGA 1YJ3A 2HOWA 2P99A 4FLIA 5FCHA 1YW7A 2GG3A 2V3XA 1WLRA 2BWVA 2Q93A 3RORA 2BHAA 2GZ5A 3L24A 3PKBA 1KQ9A 3IU7A 5CDLA 2V6CA 1W7VA 2B3HA 1MATA 2GU4A 1QZYA 4U70A 4JUQA 1M35A 3S6BA 1C23A 4IKUA 4U76A 3IG4A 5E5BA 1C24A 4MATA 2BHDA 2P98A 2GG8A 1QXWA 4U73A 2B3LA 2BH3A 3MX6A 2Q8KA 4RZZA 3TB5A 5JI6A 1WBQA 1Y1NA 3CB5A 4U6CA 1YW9A 5CLSA 3BIPA 2P9AA 3CB6A 2GGBA 4IKRA 2GG5A 4U1BA 2Q95A 1XGSA 2MATA 4FLKA 1XGOA 5FCFA 1W2MA 2DFIA 3MR1A 2OKNA 2V3YA 3FM3A 1B59A 2BWUA 2EVMA 2GU6A 4IPAA 4RZYA 2BHBA 4FO8A 4S2RP 3TAVA 5D6EA 2B3KA 2GG2A 2BB7A 1CHMA 4HXXA 2BWSA 1KP0A 2Q94A 4ZWPA 5JHUA 1PV9A 3PKCA 3PKEA 4FLLA 4A6VA 2EA4A 4KM3A 2EVOA 4S01A 4U6JA 4Z7MA 3IU9A 2GG7A 3PKAA 1XGMA 3BITA 5CNXA 3D27A 1WL9A 5CE6A 2IW2A 1BN5A 2Q92A 4A6WA 4U6EA 1C27A 3CTZA 2BWYA 3MATA 2OAZA 4IU6A 4PNCA 1JAWA 4B28A 4IF7A 2GG0A 2ZSGA 3Q6DA 4FKCA 2BHCA 3FMRA 2GU5A 4IDYA 4IECA 2GU7A 4QR8A 1N51A 1R58A 4ZWUA 1O0XA 1WL6A 4U71A 2GG9A 4U6ZA 1A16A 2G6PA 2GTXA 4IKTA 1YVMA 4PV4A 2BWXA 1XNZA 4R60A 5CDVA 1WY2A 2ADUA 2BWTA 4S2TP 1BOAA 2NQ7A 4FO7A 4RGZ1 1WN1A 5CDEA 1C21A 1B6AA 4S00A 3FMQA 1R5GA 2EA2A 2Q96A 4ZWOA 5JFRA 4U6WA 3RVAA 3L7GA 2BN7A 4IKSA 1XGNA 2GGCA 4FLJA 1WKMA 1R5HA 3IU8A 4U75A 4FUKA 2V3ZA 1QXZA 4OOKA 1C22A 2BWWA 1QXYA 3BIQA 1KQ0A 2GA2A 5D6FA 2NQ6A 3PKDA 5CIKA 4EGEA
chains in the Genus database with same CATH superfamily
2EVCA 1YW8A 4U69A 4ZNGA 1YJ3A 2HOWA 2P99A 4FLIA 5FCHA 1YW7A 2GG3A 2V3XA 1WLRA 2BWVA 2Q93A 3RORA 2BHAA 2GZ5A 3L24A 3PKBA 1KQ9A 3IU7A 5CDLA 2V6CA 1W7VA 2B3HA 1MATA 2GU4A 1QZYA 4U70A 4JUQA 1M35A 3S6BA 1C23A 4IKUA 4U76A 3IG4A 5E5BA 1C24A 4MATA 2BHDA 2P98A 2GG8A 1QXWA 4U73A 2B3LA 2BH3A 3MX6A 2Q8KA 4RZZA 3TB5A 5JI6A 1WBQA 1Y1NA 3CB5A 4U6CA 1YW9A 5CLSA 3BIPA 2P9AA 3CB6A 2GGBA 4IKRA 2GG5A 4U1BA 2Q95A 1XGSA 2MATA 4FLKA 1XGOA 5FCFA 1W2MA 2DFIA 3MR1A 2OKNA 2V3YA 3FM3A 1B59A 2BWUA 2EVMA 2GU6A 4IPAA 4RZYA 2BHBA 4FO8A 4S2RP 3TAVA 5D6EA 2B3KA 2GG2A 2BB7A 1CHMA 4HXXA 2BWSA 1KP0A 2Q94A 4ZWPA 5JHUA 1PV9A 3PKCA 3PKEA 4FLLA 4A6VA 2EA4A 4KM3A 2EVOA 4S01A 4U6JA 4Z7MA 3IU9A 2GG7A 3PKAA 1XGMA 3BITA 5CNXA 3D27A 1WL9A 5CE6A 2IW2A 1BN5A 2Q92A 4A6WA 4U6EA 1C27A 3CTZA 2BWYA 3MATA 2OAZA 4IU6A 4PNCA 1JAWA 4B28A 4IF7A 2GG0A 2ZSGA 3Q6DA 4FKCA 2BHCA 3FMRA 2GU5A 4IDYA 4IECA 2GU7A 4QR8A 1N51A 1R58A 4ZWUA 1O0XA 1WL6A 4U71A 2GG9A 4U6ZA 1A16A 2G6PA 2GTXA 4IKTA 1YVMA 4PV4A 2BWXA 1XNZA 4R60A 5CDVA 1WY2A 2ADUA 2BWTA 4S2TP 1BOAA 2NQ7A 4FO7A 4RGZ1 1WN1A 5CDEA 1C21A 1B6AA 4S00A 3FMQA 1R5GA 2EA2A 2Q96A 4ZWOA 5JFRA 4U6WA 3RVAA 3L7GA 2BN7A 4IKSA 1XGNA 2GGCA 4FLJA 1WKMA 1R5HA 3IU8A 4U75A 4FUKA 2V3ZA 1QXZA 4OOKA 1C22A 2BWWA 1QXYA 3BIQA 1KQ0A 2GA2A 5D6FA 2NQ6A 3PKDA 5CIKA 4EGEA
chains in the Genus database with same CATH topology
2EVCA 1YW8A 4U69A 4ZNGA 1YJ3A 2HOWA 2P99A 4FLIA 5FCHA 1YW7A 2GG3A 2V3XA 1WLRA 2BWVA 2Q93A 3RORA 2BHAA 2GZ5A 3L24A 3PKBA 1KQ9A 3IU7A 5CDLA 2V6CA 1W7VA 2B3HA 1MATA 2GU4A 1QZYA 4U70A 4JUQA 1M35A 3S6BA 1C23A 4IKUA 4U76A 3IG4A 5E5BA 1C24A 4MATA 2BHDA 2P98A 2GG8A 1QXWA 4U73A 2B3LA 2BH3A 3MX6A 2Q8KA 4RZZA 3TB5A 5JI6A 1WBQA 1Y1NA 3CB5A 4U6CA 1YW9A 5CLSA 3BIPA 2P9AA 3CB6A 2GGBA 4IKRA 2GG5A 4U1BA 2Q95A 1XGSA 2MATA 4FLKA 1XGOA 5FCFA 1W2MA 2DFIA 3MR1A 2OKNA 2V3YA 3FM3A 1B59A 2BWUA 2EVMA 2GU6A 4IPAA 4RZYA 2BHBA 4FO8A 4S2RP 3TAVA 5D6EA 2B3KA 2GG2A 2BB7A 1CHMA 4HXXA 2BWSA 1KP0A 2Q94A 4ZWPA 5JHUA 1PV9A 3PKCA 3PKEA 4FLLA 4A6VA 2EA4A 4KM3A 2EVOA 4S01A 4U6JA 4Z7MA 3IU9A 2GG7A 3PKAA 1XGMA 3BITA 5CNXA 3D27A 1WL9A 5CE6A 2IW2A 1BN5A 2Q92A 4A6WA 4U6EA 1C27A 3CTZA 2BWYA 3MATA 2OAZA 4IU6A 4PNCA 1JAWA 4B28A 4IF7A 2GG0A 2ZSGA 3Q6DA 4FKCA 2BHCA 3FMRA 2GU5A 4IDYA 4IECA 2GU7A 4QR8A 1N51A 1R58A 4ZWUA 1O0XA 1WL6A 4U71A 2GG9A 4U6ZA 1A16A 2G6PA 2GTXA 4IKTA 1YVMA 4PV4A 2BWXA 1XNZA 4R60A 5CDVA 1WY2A 2ADUA 2BWTA 4S2TP 1BOAA 2NQ7A 4FO7A 4RGZ1 1WN1A 5CDEA 1C21A 1B6AA 4S00A 3FMQA 1R5GA 2EA2A 2Q96A 4ZWOA 5JFRA 4U6WA 3RVAA 3L7GA 2BN7A 4IKSA 1XGNA 2GGCA 4FLJA 1WKMA 1R5HA 3IU8A 4U75A 4FUKA 2V3ZA 1QXZA 4OOKA 1C22A 2BWWA 1QXYA 3BIQA 1KQ0A 2GA2A 5D6FA 2NQ6A 3PKDA 5CIKA 4EGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EVC A;  1YW8 A;  4U69 A;  4ZNG A;  1YJ3 A;  2HOW A;  2P99 A;  4FLI A;  5FCH A;  1YW7 A;  2GG3 A;  2V3X A;  1WLR A;  2BWV A;  2Q93 A;  3ROR A;  2BHA A;  2GZ5 A;  3L24 A;  3PKB A;  1KQ9 A;  3IU7 A;  5CDL A;  2V6C A;  1W7V A;  2B3H A;  1MAT A;  2GU4 A;  1QZY A;  4U70 A;  4JUQ A;  1M35 A;  3S6B A;  1C23 A;  4IKU A;  4U76 A;  3IG4 A;  5E5B A;  1C24 A;  4MAT A;  2BHD A;  2P98 A;  2GG8 A;  1QXW A;  4U73 A;  2B3L A;  2BH3 A;  3MX6 A;  2Q8K A;  4RZZ A;  3TB5 A;  5JI6 A;  1WBQ A;  1Y1N A;  3CB5 A;  4U6C A;  1YW9 A;  5CLS A;  3BIP A;  2P9A A;  3CB6 A;  2GGB A;  4IKR A;  2GG5 A;  4U1B A;  2Q95 A;  1XGS A;  2MAT A;  4FLK A;  1XGO A;  5FCF A;  1W2M A;  2DFI A;  3MR1 A;  2OKN A;  2V3Y A;  3FM3 A;  1B59 A;  2BWU A;  2EVM A;  2GU6 A;  4IPA A;  4RZY A;  2BHB A;  4FO8 A;  4S2R P;  3TAV A;  5D6E A;  2B3K A;  2GG2 A;  2BB7 A;  1CHM A;  4HXX A;  2BWS A;  1KP0 A;  2Q94 A;  4ZWP A;  5JHU A;  1PV9 A;  3PKC A;  3PKE A;  4FLL A;  4A6V A;  2EA4 A;  4KM3 A;  2EVO A;  4S01 A;  4U6J A;  4Z7M A;  3IU9 A;  2GG7 A;  3PKA A;  1XGM A;  3BIT A;  5CNX A;  3D27 A;  1WL9 A;  5CE6 A;  2IW2 A;  1BN5 A;  2Q92 A;  4A6W A;  4U6E A;  1C27 A;  3CTZ A;  2BWY A;  3MAT A;  2OAZ A;  4IU6 A;  4PNC A;  1JAW A;  4B28 A;  4IF7 A;  2GG0 A;  2ZSG A;  3Q6D A;  4FKC A;  2BHC A;  3FMR A;  2GU5 A;  4IDY A;  4IEC A;  2GU7 A;  4QR8 A;  1N51 A;  1R58 A;  4ZWU A;  1O0X A;  1WL6 A;  4U71 A;  2GG9 A;  4U6Z A;  1A16 A;  2G6P A;  2GTX A;  4IKT A;  1YVM A;  4PV4 A;  2BWX A;  1XNZ A;  4R60 A;  5CDV A;  1WY2 A;  2ADU A;  2BWT A;  4S2T P;  1BOA A;  2NQ7 A;  4FO7 A;  4RGZ 1;  1WN1 A;  5CDE A;  1C21 A;  1B6A A;  4S00 A;  3FMQ A;  1R5G A;  2EA2 A;  2Q96 A;  4ZWO A;  5JFR A;  4U6W A;  3RVA A;  3L7G A;  2BN7 A;  4IKS A;  1XGN A;  2GGC A;  4FLJ A;  1WKM A;  1R5H A;  3IU8 A;  4U75 A;  4FUK A;  2V3Z A;  1QXZ A;  4OOK A;  1C22 A;  2BWW A;  1QXY A;  3BIQ A;  1KQ0 A;  2GA2 A;  5D6F A;  2NQ6 A;  3PKD A;  5CIK A;  4EGE A; 
#chains in the Genus database with same CATH topology
 2EVC A;  1YW8 A;  4U69 A;  4ZNG A;  1YJ3 A;  2HOW A;  2P99 A;  4FLI A;  5FCH A;  1YW7 A;  2GG3 A;  2V3X A;  1WLR A;  2BWV A;  2Q93 A;  3ROR A;  2BHA A;  2GZ5 A;  3L24 A;  3PKB A;  1KQ9 A;  3IU7 A;  5CDL A;  2V6C A;  1W7V A;  2B3H A;  1MAT A;  2GU4 A;  1QZY A;  4U70 A;  4JUQ A;  1M35 A;  3S6B A;  1C23 A;  4IKU A;  4U76 A;  3IG4 A;  5E5B A;  1C24 A;  4MAT A;  2BHD A;  2P98 A;  2GG8 A;  1QXW A;  4U73 A;  2B3L A;  2BH3 A;  3MX6 A;  2Q8K A;  4RZZ A;  3TB5 A;  5JI6 A;  1WBQ A;  1Y1N A;  3CB5 A;  4U6C A;  1YW9 A;  5CLS A;  3BIP A;  2P9A A;  3CB6 A;  2GGB A;  4IKR A;  2GG5 A;  4U1B A;  2Q95 A;  1XGS A;  2MAT A;  4FLK A;  1XGO A;  5FCF A;  1W2M A;  2DFI A;  3MR1 A;  2OKN A;  2V3Y A;  3FM3 A;  1B59 A;  2BWU A;  2EVM A;  2GU6 A;  4IPA A;  4RZY A;  2BHB A;  4FO8 A;  4S2R P;  3TAV A;  5D6E A;  2B3K A;  2GG2 A;  2BB7 A;  1CHM A;  4HXX A;  2BWS A;  1KP0 A;  2Q94 A;  4ZWP A;  5JHU A;  1PV9 A;  3PKC A;  3PKE A;  4FLL A;  4A6V A;  2EA4 A;  4KM3 A;  2EVO A;  4S01 A;  4U6J A;  4Z7M A;  3IU9 A;  2GG7 A;  3PKA A;  1XGM A;  3BIT A;  5CNX A;  3D27 A;  1WL9 A;  5CE6 A;  2IW2 A;  1BN5 A;  2Q92 A;  4A6W A;  4U6E A;  1C27 A;  3CTZ A;  2BWY A;  3MAT A;  2OAZ A;  4IU6 A;  4PNC A;  1JAW A;  4B28 A;  4IF7 A;  2GG0 A;  2ZSG A;  3Q6D A;  4FKC A;  2BHC A;  3FMR A;  2GU5 A;  4IDY A;  4IEC A;  2GU7 A;  4QR8 A;  1N51 A;  1R58 A;  4ZWU A;  1O0X A;  1WL6 A;  4U71 A;  2GG9 A;  4U6Z A;  1A16 A;  2G6P A;  2GTX A;  4IKT A;  1YVM A;  4PV4 A;  2BWX A;  1XNZ A;  4R60 A;  5CDV A;  1WY2 A;  2ADU A;  2BWT A;  4S2T P;  1BOA A;  2NQ7 A;  4FO7 A;  4RGZ 1;  1WN1 A;  5CDE A;  1C21 A;  1B6A A;  4S00 A;  3FMQ A;  1R5G A;  2EA2 A;  2Q96 A;  4ZWO A;  5JFR A;  4U6W A;  3RVA A;  3L7G A;  2BN7 A;  4IKS A;  1XGN A;  2GGC A;  4FLJ A;  1WKM A;  1R5H A;  3IU8 A;  4U75 A;  4FUK A;  2V3Z A;  1QXZ A;  4OOK A;  1C22 A;  2BWW A;  1QXY A;  3BIQ A;  1KQ0 A;  2GA2 A;  5D6F A;  2NQ6 A;  3PKD A;  5CIK A;  4EGE A; 
#chains in the Genus database with same CATH homology
 2EVC A;  1YW8 A;  4U69 A;  4ZNG A;  1YJ3 A;  2HOW A;  2P99 A;  4FLI A;  5FCH A;  1YW7 A;  2GG3 A;  2V3X A;  1WLR A;  2BWV A;  2Q93 A;  3ROR A;  2BHA A;  2GZ5 A;  3L24 A;  3PKB A;  1KQ9 A;  3IU7 A;  5CDL A;  2V6C A;  1W7V A;  2B3H A;  1MAT A;  2GU4 A;  1QZY A;  4U70 A;  4JUQ A;  1M35 A;  3S6B A;  1C23 A;  4IKU A;  4U76 A;  3IG4 A;  5E5B A;  1C24 A;  4MAT A;  2BHD A;  2P98 A;  2GG8 A;  1QXW A;  4U73 A;  2B3L A;  2BH3 A;  3MX6 A;  2Q8K A;  4RZZ A;  3TB5 A;  5JI6 A;  1WBQ A;  1Y1N A;  3CB5 A;  4U6C A;  1YW9 A;  5CLS A;  3BIP A;  2P9A A;  3CB6 A;  2GGB A;  4IKR A;  2GG5 A;  4U1B A;  2Q95 A;  1XGS A;  2MAT A;  4FLK A;  1XGO A;  5FCF A;  1W2M A;  2DFI A;  3MR1 A;  2OKN A;  2V3Y A;  3FM3 A;  1B59 A;  2BWU A;  2EVM A;  2GU6 A;  4IPA A;  4RZY A;  2BHB A;  4FO8 A;  4S2R P;  3TAV A;  5D6E A;  2B3K A;  2GG2 A;  2BB7 A;  1CHM A;  4HXX A;  2BWS A;  1KP0 A;  2Q94 A;  4ZWP A;  5JHU A;  1PV9 A;  3PKC A;  3PKE A;  4FLL A;  4A6V A;  2EA4 A;  4KM3 A;  2EVO A;  4S01 A;  4U6J A;  4Z7M A;  3IU9 A;  2GG7 A;  3PKA A;  1XGM A;  3BIT A;  5CNX A;  3D27 A;  1WL9 A;  5CE6 A;  2IW2 A;  1BN5 A;  2Q92 A;  4A6W A;  4U6E A;  1C27 A;  3CTZ A;  2BWY A;  3MAT A;  2OAZ A;  4IU6 A;  4PNC A;  1JAW A;  4B28 A;  4IF7 A;  2GG0 A;  2ZSG A;  3Q6D A;  4FKC A;  2BHC A;  3FMR A;  2GU5 A;  4IDY A;  4IEC A;  2GU7 A;  4QR8 A;  1N51 A;  1R58 A;  4ZWU A;  1O0X A;  1WL6 A;  4U71 A;  2GG9 A;  4U6Z A;  1A16 A;  2G6P A;  2GTX A;  4IKT A;  1YVM A;  4PV4 A;  2BWX A;  1XNZ A;  4R60 A;  5CDV A;  1WY2 A;  2ADU A;  2BWT A;  4S2T P;  1BOA A;  2NQ7 A;  4FO7 A;  4RGZ 1;  1WN1 A;  5CDE A;  1C21 A;  1B6A A;  4S00 A;  3FMQ A;  1R5G A;  2EA2 A;  2Q96 A;  4ZWO A;  5JFR A;  4U6W A;  3RVA A;  3L7G A;  2BN7 A;  4IKS A;  1XGN A;  2GGC A;  4FLJ A;  1WKM A;  1R5H A;  3IU8 A;  4U75 A;  4FUK A;  2V3Z A;  1QXZ A;  4OOK A;  1C22 A;  2BWW A;  1QXY A;  3BIQ A;  1KQ0 A;  2GA2 A;  5D6F A;  2NQ6 A;  3PKD A;  5CIK A;  4EGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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