1YJ9E

Crystal structure of the mutant 50s ribosomal subunit of haloarcula marismortui containing a three residue deletion in l22
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 36
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yj9E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yj9E01
5JVGE 3CCSE 1VQ5E 3CCLE 1Q81G 3PIPE 4IOCE 4IO9E 1JJ2E 2QEXE 1VQME 3I55E 4WF9E 1VQPE 5H1SI 5JVHE 1YIJE 3OW2E 3CXCE 1QVGE 1YJNE 1VQ4E 3PIOE 3CC4E 3CCEE 3CCQE 5GAGG 3G4SE 2ZJPE 3CCUE 1QVFE 3CCME 1VQKE 1W2BE 2OTLE 1YI2E 5GAEG 1N8RG 4WCEE 2QA4E 3I56E 1YITE 3CC2E 3DLLE 4WFNE 1M90G 4IOAE 3J7ZG 1YJWE 5HL7E 5DM7E 3CPWE 1VQNE 1VQ9E 5DM6E 1K73G 1VQ7E 1Q7YG 3CMAE 1Q82G 3CCVE 1K9MG 1M1KG 3CD6E 3CF5E 4UY8G 1RL6A 3G71E 2ZJRE 5GADG 5AN9B 4WFAE 1VQ8E 3CCRE 1YHQE 3CMEE 5MLCH 1VQOE 1KQSE 1Q86G 1KC8G 3CCJE 4WFBE 2OTJE 1VQLE 3CC7E 1K8AG 1VQ6E 2ZJQE 5GAHG 4U67E 1YJ9E 2CQLA 1NJIG 3G6EE 1KD1G 1S72E
chains in the Genus database with same CATH superfamily
5JVGE 3CCSE 1VQ5E 3CCLE 1Q81G 3PIPE 2HKDA 4IOCE 4IO9E 1JJ2E 2QEXE 5B3MO 1VQME 3I55E 4WF9E 1VQPE 5H1SI 5JVHE 1YIJE 2OY8A 3OW2E 3IG9A 3CKGA 3IGEA 3CXCE 1QVGE 1YJNE 3AUMO 1VQ4E 3PIOE 3CC4E 3CCEE 3CCQE 2I5ZO 1RJLC 5B10O 5GAGG 3G4SE 2ZJPE 3CCUE 2FKGA 1QVFE 3CCME 1VQKE 1W2BE 2OTLE 2OL6O 3EC5A 1YI2E 1OSPO 2OY1O 5GAEG 1N8RG 4WCEE 2QA4E 3I56E 1YITE 3CC2E 5B2AO 1P4PA 3DLLE 4WFNE 1M90G 2OL8O 3J7ZG 4IOAE 1YJWE 5HL7E 5DM7E 3CPWE 1VQNE 1VQ9E 5DM6E 1K73G 1VQ7E 1Q7YG 3CMAE 1Q82G 3CCVE 1K9MG 1M1KG 3CD6E 1FJ1E 3CF5E 4UY8G 1RL6A 3G71E 2ZJRE 2I5VO 5GADG 5AN9B 2OL7A 4WFAE 1VQ8E 3CCRE 1YHQE 3CMEE 2G8CO 5MLCH 1VQOE 1KQSE 2OY5O 1Q86G 1KC8G 3CKFA 3CCJE 4WFBE 2OTJE 1VQLE 2PI3O 3CC7E 1K8AG 1VQ6E 2ZJQE 5GAHG 4U67E 1YJ9E 2AF5A 2OYBO 2CQLA 1NJIG 2FKJA 3G6EE 5B11O 1KD1G 1S72E 2OY7A
chains in the Genus database with same CATH topology
5JVGE 3CCSE 1VQ5E 3CCLE 1Q81G 3PIPE 4IOCE 4IO9E 1JJ2E 2QEXE 1VQME 3I55E 4WF9E 1VQPE 5H1SI 5JVHE 1YIJE 3OW2E 3CXCE 1QVGE 1YJNE 1VQ4E 3PIOE 3CC4E 3CCEE 3CCQE 5GAGG 3G4SE 2ZJPE 3CCUE 1QVFE 3CCME 1VQKE 1W2BE 2OTLE 1YI2E 5GAEG 1N8RG 4WCEE 2QA4E 3I56E 1YITE 3CC2E 3DLLE 4WFNE 1M90G 4IOAE 3J7ZG 1YJWE 5HL7E 5DM7E 3CPWE 1VQNE 1VQ9E 5DM6E 1K73G 1VQ7E 1Q7YG 3CMAE 1Q82G 3CCVE 1K9MG 1M1KG 3CD6E 3CF5E 4UY8G 1RL6A 3G71E 2ZJRE 5GADG 5AN9B 4WFAE 1VQ8E 3CCRE 1YHQE 3CMEE 5MLCH 1VQOE 1KQSE 1Q86G 1KC8G 3CCJE 4WFBE 2OTJE 1VQLE 3CC7E 1K8AG 1VQ6E 2ZJQE 5GAHG 4U67E 1YJ9E 2CQLA 1NJIG 3G6EE 1KD1G 1S72E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JVG E;  3CCS E;  1VQ5 E;  3CCL E;  1Q81 G;  3PIP E;  4IOC E;  4IO9 E;  1JJ2 E;  2QEX E;  1VQM E;  3I55 E;  4WF9 E;  1VQP E;  5H1S I;  5JVH E;  1YIJ E;  3OW2 E;  3CXC E;  1QVG E;  1YJN E;  1VQ4 E;  3PIO E;  3CC4 E;  3CCE E;  3CCQ E;  5GAG G;  3G4S E;  2ZJP E;  3CCU E;  1QVF E;  3CCM E;  1VQK E;  1W2B E;  2OTL E;  1YI2 E;  5GAE G;  1N8R G;  4WCE E;  2QA4 E;  3I56 E;  1YIT E;  3CC2 E;  3DLL E;  4WFN E;  1M90 G;  4IOA E;  3J7Z G;  1YJW E;  5HL7 E;  5DM7 E;  3CPW E;  1VQN E;  1VQ9 E;  5DM6 E;  1K73 G;  1VQ7 E;  1Q7Y G;  3CMA E;  1Q82 G;  3CCV E;  1K9M G;  1M1K G;  3CD6 E;  3CF5 E;  4UY8 G;  1RL6 A;  3G71 E;  2ZJR E;  5GAD G;  5AN9 B;  4WFA E;  1VQ8 E;  3CCR E;  1YHQ E;  3CME E;  5MLC H;  1VQO E;  1KQS E;  1Q86 G;  1KC8 G;  3CCJ E;  4WFB E;  2OTJ E;  1VQL E;  3CC7 E;  1K8A G;  1VQ6 E;  2ZJQ E;  5GAH G;  4U67 E;  1YJ9 E;  2CQL A;  1NJI G;  3G6E E;  1KD1 G;  1S72 E; 
#chains in the Genus database with same CATH topology
 5JVG E;  3CCS E;  1VQ5 E;  3CCL E;  1Q81 G;  3PIP E;  2HKD A;  4IOC E;  4IO9 E;  1JJ2 E;  2QEX E;  5B3M O;  1VQM E;  3I55 E;  4WF9 E;  1VQP E;  5H1S I;  5JVH E;  1YIJ E;  2OY8 A;  3OW2 E;  3IG9 A;  3CKG A;  3IGE A;  3CXC E;  1QVG E;  1YJN E;  3AUM O;  1VQ4 E;  3PIO E;  3CC4 E;  3CCE E;  3CCQ E;  2I5Z O;  1RJL C;  5B10 O;  5GAG G;  3G4S E;  2ZJP E;  3CCU E;  2FKG A;  1QVF E;  3CCM E;  1VQK E;  1W2B E;  2OTL E;  2OL6 O;  3EC5 A;  1YI2 E;  1OSP O;  2OY1 O;  5GAE G;  1N8R G;  4WCE E;  2QA4 E;  3I56 E;  1YIT E;  3CC2 E;  5B2A O;  1P4P A;  3DLL E;  4WFN E;  1M90 G;  2OL8 O;  3J7Z G;  4IOA E;  1YJW E;  5HL7 E;  5DM7 E;  3CPW E;  1VQN E;  1VQ9 E;  5DM6 E;  1K73 G;  1VQ7 E;  1Q7Y G;  3CMA E;  1Q82 G;  3CCV E;  1K9M G;  1M1K G;  3CD6 E;  1FJ1 E;  3CF5 E;  4UY8 G;  1RL6 A;  3G71 E;  2ZJR E;  2I5V O;  5GAD G;  5AN9 B;  2OL7 A;  4WFA E;  1VQ8 E;  3CCR E;  1YHQ E;  3CME E;  2G8C O;  5MLC H;  1VQO E;  1KQS E;  2OY5 O;  1Q86 G;  1KC8 G;  3CKF A;  3CCJ E;  4WFB E;  2OTJ E;  1VQL E;  2PI3 O;  3CC7 E;  1K8A G;  1VQ6 E;  2ZJQ E;  5GAH G;  4U67 E;  1YJ9 E;  2AF5 A;  2OYB O;  2CQL A;  1NJI G;  2FKJ A;  3G6E E;  5B11 O;  1KD1 G;  1S72 E;  2OY7 A; 
#chains in the Genus database with same CATH homology
 5JVG E;  3CCS E;  1VQ5 E;  3CCL E;  1Q81 G;  3PIP E;  4IOC E;  4IO9 E;  1JJ2 E;  2QEX E;  1VQM E;  3I55 E;  4WF9 E;  1VQP E;  5H1S I;  5JVH E;  1YIJ E;  3OW2 E;  3CXC E;  1QVG E;  1YJN E;  1VQ4 E;  3PIO E;  3CC4 E;  3CCE E;  3CCQ E;  5GAG G;  3G4S E;  2ZJP E;  3CCU E;  1QVF E;  3CCM E;  1VQK E;  1W2B E;  2OTL E;  1YI2 E;  5GAE G;  1N8R G;  4WCE E;  2QA4 E;  3I56 E;  1YIT E;  3CC2 E;  3DLL E;  4WFN E;  1M90 G;  4IOA E;  3J7Z G;  1YJW E;  5HL7 E;  5DM7 E;  3CPW E;  1VQN E;  1VQ9 E;  5DM6 E;  1K73 G;  1VQ7 E;  1Q7Y G;  3CMA E;  1Q82 G;  3CCV E;  1K9M G;  1M1K G;  3CD6 E;  3CF5 E;  4UY8 G;  1RL6 A;  3G71 E;  2ZJR E;  5GAD G;  5AN9 B;  4WFA E;  1VQ8 E;  3CCR E;  1YHQ E;  3CME E;  5MLC H;  1VQO E;  1KQS E;  1Q86 G;  1KC8 G;  3CCJ E;  4WFB E;  2OTJ E;  1VQL E;  3CC7 E;  1K8A G;  1VQ6 E;  2ZJQ E;  5GAH G;  4U67 E;  1YJ9 E;  2CQL A;  1NJI G;  3G6E E;  1KD1 G;  1S72 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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