1Z52A

Proaerolysin mutant w373l
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
467
structure length
451
Chain Sequence
PVYPDQLRLFSLGQGVCGDKYRPVNREEAQSVKSNIVGMMGQWQISGLANGWVIMGPGYNGEIKPGTASNTWCYPTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSANFIKPTSYLAHYLGYAWVGGNHSQYVGEDMDVTRDGDGWVIRGNNDGGCDGYRCGDKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTVVGWAVNDSDTPQSGYDVTLRYDTATNWSKTNTYGLSEKVTTKNKFKWPLVGETELSIEIAANQSWASQNGGSTTTSLSQSVRPTVPARSKIPVKIELYKADISYPYEFKADVSYDLTLSGFLRWGGNAWYTHPDNRPNWNHTFVIGPYKDKASSIRYQWDKRYIPGEVKWWDLNWTIQQNGLSTMQNNLARVLRPVRAGITGDFSAESQFAGNIEIGAPVPLAGLRLEIPLDAQELSGLGFNNVSLSVTPAAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Aerolysin
publication title Crystal Structure of Proaerolysin at 2.3 A Resolution and Structural Analyses of Single-site Mutants as a Basis for Understanding Membrane Insertion of the Toxin
rcsb
source organism Aeromonas hydrophila
total genus 108
structure length 451
sequence length 467
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-03-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01117 Aerolysin Aerolysin toxin
A PF03440 APT Aerolysin/Pertussis toxin (APT) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.15.10 Mainly Beta Beta Complex Proaerolysin; Chain A, domain 3 Proaerolysin, chain A, domain 3 1z52A03
3.10.40.10 Alpha Beta Roll Pertussis Toxin; Chain B, domain 1 Aerolysin/Pertussis toxin (APT), N-terminal domain 1z52A01
3.30.412.10 Alpha Beta 2-Layer Sandwich Proaerolysin; Chain A, domain 2 Proaerolysin, chain A, domain 2 1z52A02
1W3AA 3G4OA 1PRTB 3G4NA 1Z52A 1BCPC 1W3GA 1PTOC 3C0MA 3C0NA 1W3FA 1PREA 1UYJA 1PRTC 3C0OA 2D42A 3ZJXA 1BCPB 1PTOB 1PTOH
chains in the Genus database with same CATH superfamily
1W3AA 3G4OA 1PRTB 3G4NA 1Z52A 1BCPC 1W3GA 1PTOC 3C0MA 3C0NA 1W3FA 1PREA 1UYJA 1PRTC 3C0OA 2D42A 3ZJXA 1BCPB 1PTOB 1PTOH
chains in the Genus database with same CATH topology
1W3AA 3G4OA 1PRTB 3G4NA 1Z52A 1BCPC 1W3GA 1PTOC 3C0MA 3C0NA 1W3FA 1PREA 1UYJA 1PRTC 3C0OA 2D42A 3ZJXA 1BCPB 1PTOB 1PTOH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W3A A;  3G4O A;  1PRT B;  3G4N A;  1Z52 A;  1BCP C;  1W3G A;  1PTO C;  3C0M A;  3C0N A;  1W3F A;  1PRE A;  1UYJ A;  1PRT C;  3C0O A;  2D42 A;  3ZJX A;  1BCP B;  1PTO B;  1PTO H; 
#chains in the Genus database with same CATH topology
 1W3A A;  3G4O A;  1PRT B;  3G4N A;  1Z52 A;  1BCP C;  1W3G A;  1PTO C;  3C0M A;  3C0N A;  1W3F A;  1PRE A;  1UYJ A;  1PRT C;  3C0O A;  2D42 A;  3ZJX A;  1BCP B;  1PTO B;  1PTO H; 
#chains in the Genus database with same CATH homology
 1W3A A;  3G4O A;  1PRT B;  3G4N A;  1Z52 A;  1BCP C;  1W3G A;  1PTO C;  3C0M A;  3C0N A;  1W3F A;  1PRE A;  1UYJ A;  1PRT C;  3C0O A;  2D42 A;  3ZJX A;  1BCP B;  1PTO B;  1PTO H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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