1Z9EA

Solution structure of the hiv-1 integrase-binding domain in ledgf/p75
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
83
structure length
83
Chain Sequence
b'SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PC4 and SFRS1 interacting protein 2
publication title Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
pubmed doi rcsb
source organism Homo sapiens
molecule tags Protein binding/transcription
total genus 24
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2005-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11467 LEDGF Lens epithelium-derived growth factor (LEDGF)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 1z9eA00
3U88C 3NFQA 2N3AB 2XPNA 3HPHE 2XPPA 3OAKA 3F9KC 2XPOA 1EO0A 1Z9EA 3O8ZA 1WJTA 3HPGG 2B4JC 2XPLA
chains in the Genus database with same CATH superfamily
4BPXB 3VGOA 3HPHE 4OC0A 5ELYA 4P45A 3HPGG 3BUMB 5AXIA 3BUXB 4NGMA 3VRQA 2DLAA 4NGTA 4P4IA 3BI0A 4MCSA 3VRNA 3PT1A 3OAKA 5HKWA 5HKYA 2OR4A 2XEIA 4OC3A 4P4DA 3VRPA 2C6CA 3U88C 3KASA 4JZ0A 4LQGA 3BHXA 2CBLA 1DE4C 1Z8LA 4NGPA 4P4EA 1EO0A 4OC4A 3D7HA 5J3XA 5F13A 2PVWA 2XPNA 3FECA 4P44A 3PLFB 4A4CA 3SJGA 3HMJG 1CX8A 3BI1A 4BTFA 5F09A 4RR2B 3RBUA 4NGRA 2XPPA 3F9KC 1FBVA 3S9LA 2CIJA 3VROA 4OC5A 2JBJA 4NGQA 3FF3A 2UV8G 4NGSA 4MCRA 4W9YA 3FEDA 1YVHA 2Y1MA 2Y1NA 2N3AB 5BY0A 4P4FA 3D7FA 1B47A 3SJXA 4GPLB 4A4BA 4P4JA 3S9MA 2B4JC 3BXMA 2JBKA 3D7GA 3OB1B 2XEFA 3BUNB 2PVVA 4MCQA 2C6PA 1WJTA 3PFVA 3VRRA 3BUOB 3IWWA 2VKZG 3NFQA 5D29A 3O8ZA 2XEJA 4BPUB 4X3RA 4OC2A 2XEGA 3S9NA 3OB2B 4NGNA 5HKZA 2OOTA 3D7DA 3SJEA 3SJFA 3ZNIA 4P4BA 4MCPA 2XPOA 1Z9EA 4JYWA 3BUWB 4BPWB 3OP0A 4OC1A 4OMEA 3FEEA 2C6GA 2XPLA
chains in the Genus database with same CATH topology
3U88C 3NFQA 2N3AB 2XPNA 3HPHE 2XPPA 3OAKA 3F9KC 2XPOA 1EO0A 1Z9EA 3O8ZA 1WJTA 3HPGG 2B4JC 2XPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U88 C;  3NFQ A;  2N3A B;  2XPN A;  3HPH E;  2XPP A;  3OAK A;  3F9K C;  2XPO A;  1EO0 A;  1Z9E A;  3O8Z A;  1WJT A;  3HPG G;  2B4J C;  2XPL A; 
#chains in the Genus database with same CATH topology
 4BPX B;  3VGO A;  3HPH E;  4OC0 A;  5ELY A;  4P45 A;  3HPG G;  3BUM B;  5AXI A;  3BUX B;  4NGM A;  3VRQ A;  2DLA A;  4NGT A;  4P4I A;  3BI0 A;  4MCS A;  3VRN A;  3PT1 A;  3OAK A;  5HKW A;  5HKY A;  2OR4 A;  2XEI A;  4OC3 A;  4P4D A;  3VRP A;  2C6C A;  3U88 C;  3KAS A;  4JZ0 A;  4LQG A;  3BHX A;  2CBL A;  1DE4 C;  1Z8L A;  4NGP A;  4P4E A;  1EO0 A;  4OC4 A;  3D7H A;  5J3X A;  5F13 A;  2PVW A;  2XPN A;  3FEC A;  4P44 A;  3PLF B;  4A4C A;  3SJG A;  3HMJ G;  1CX8 A;  3BI1 A;  4BTF A;  5F09 A;  4RR2 B;  3RBU A;  4NGR A;  2XPP A;  3F9K C;  1FBV A;  3S9L A;  2CIJ A;  3VRO A;  4OC5 A;  2JBJ A;  4NGQ A;  3FF3 A;  2UV8 G;  4NGS A;  4MCR A;  4W9Y A;  3FED A;  1YVH A;  2Y1M A;  2Y1N A;  2N3A B;  5BY0 A;  4P4F A;  3D7F A;  1B47 A;  3SJX A;  4GPL B;  4A4B A;  4P4J A;  3S9M A;  2B4J C;  3BXM A;  2JBK A;  3D7G A;  3OB1 B;  2XEF A;  3BUN B;  2PVV A;  4MCQ A;  2C6P A;  1WJT A;  3PFV A;  3VRR A;  3BUO B;  3IWW A;  2VKZ G;  3NFQ A;  5D29 A;  3O8Z A;  2XEJ A;  4BPU B;  4X3R A;  4OC2 A;  2XEG A;  3S9N A;  3OB2 B;  4NGN A;  5HKZ A;  2OOT A;  3D7D A;  3SJE A;  3SJF A;  3ZNI A;  4P4B A;  4MCP A;  2XPO A;  1Z9E A;  4JYW A;  3BUW B;  4BPW B;  3OP0 A;  4OC1 A;  4OME A;  3FEE A;  2C6G A;  2XPL A; 
#chains in the Genus database with same CATH homology
 3U88 C;  3NFQ A;  2N3A B;  2XPN A;  3HPH E;  2XPP A;  3OAK A;  3F9K C;  2XPO A;  1EO0 A;  1Z9E A;  3O8Z A;  1WJT A;  3HPG G;  2B4J C;  2XPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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