1Z9EA

Solution structure of the hiv-1 integrase-binding domain in ledgf/p75
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
83
structure length
83
Chain Sequence
SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PC4 and SFRS1 interacting protein 2
publication title Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
pubmed doi rcsb
source organism Homo sapiens
molecule tags Protein binding/transcription
total genus 24
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2005-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11467 LEDGF Lens epithelium-derived growth factor (LEDGF)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 1z9eA00
2XPNA 2XPLA 3U88C 1Z9EA 3NFQA 2B4JC 3HPHE 1WJTA 3O8ZA 3OAKA 1EO0A 2XPOA 3F9KC 3HPGG 2XPPA 2N3AB
chains in the Genus database with same CATH superfamily
5HKZA 4NGMA 3BHXA 2C6PA 5HKYA 4JYWA 3FEEA 4P4BA 4OC2A 3BUWB 2XEGA 2DLAA 3HMJG 3RBUA 4RR2B 2XEJA 5AXIA 3D7FA 3BI1A 4P45A 5BY0A 3BXMA 2XPNA 3NFQA 2JBKA 2XEFA 4NGNA 4NGPA 3OB1B 3SJEA 4BPWB 3FECA 3BUNB 4OC4A 5F13A 3ZNIA 1CX8A 3VRPA 2C6CA 2Y1MA 3SJGA 3PFVA 3SJFA 1DE4C 2UV8G 4OMEA 4NGSA 2B4JC 4GPLB 3HPHE 3S9LA 4X3RA 1EO0A 5ELYA 2N3AB 4JZ0A 3VRRA 2C6GA 5HKWA 2XPOA 4P4EA 3D7GA 4MCPA 4NGTA 3VRNA 4BPXB 3D7DA 3FF3A 3O8ZA 3OAKA 4NGRA 3SJXA 2CIJA 5J3XA 3VROA 4A4BA 1FBVA 4OC1A 3S9NA 1WJTA 3BI0A 2PVWA 2XEIA 1B47A 1YVHA 2XPPA 1Z8LA 2OOTA 3OB2B 3VRQA 3PT1A 3F9KC 3FEDA 2JBJA 4BPUB 2VKZG 3OP0A 2PVVA 4P4JA 4NGQA 4MCSA 3BUMB 4W9YA 3IWWA 3BUXB 4BTFA 4P4IA 2OR4A 3BUOB 2CBLA 3S9MA 2Y1NA 5F09A 1Z9EA 3KASA 4OC3A 4P44A 4A4CA 3VGOA 4OC5A 2XPLA 4LQGA 5D29A 3D7HA 3HPGG 4P4FA 4P4DA 4MCRA 3PLFB 3U88C 4MCQA 4OC0A
chains in the Genus database with same CATH topology
2XPNA 2XPLA 3U88C 1Z9EA 3NFQA 2B4JC 3HPHE 1WJTA 3O8ZA 3OAKA 1EO0A 2XPOA 3F9KC 3HPGG 2XPPA 2N3AB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPN A;  2XPL A;  3U88 C;  1Z9E A;  3NFQ A;  2B4J C;  3HPH E;  1WJT A;  3O8Z A;  3OAK A;  1EO0 A;  2XPO A;  3F9K C;  3HPG G;  2XPP A;  2N3A B; 
#chains in the Genus database with same CATH topology
 5HKZ A;  4NGM A;  3BHX A;  2C6P A;  5HKY A;  4JYW A;  3FEE A;  4P4B A;  4OC2 A;  3BUW B;  2XEG A;  2DLA A;  3HMJ G;  3RBU A;  4RR2 B;  2XEJ A;  5AXI A;  3D7F A;  3BI1 A;  4P45 A;  5BY0 A;  3BXM A;  2XPN A;  3NFQ A;  2JBK A;  2XEF A;  4NGN A;  4NGP A;  3OB1 B;  3SJE A;  4BPW B;  3FEC A;  3BUN B;  4OC4 A;  5F13 A;  3ZNI A;  1CX8 A;  3VRP A;  2C6C A;  2Y1M A;  3SJG A;  3PFV A;  3SJF A;  1DE4 C;  2UV8 G;  4OME A;  4NGS A;  2B4J C;  4GPL B;  3HPH E;  3S9L A;  4X3R A;  1EO0 A;  5ELY A;  2N3A B;  4JZ0 A;  3VRR A;  2C6G A;  5HKW A;  2XPO A;  4P4E A;  3D7G A;  4MCP A;  4NGT A;  3VRN A;  4BPX B;  3D7D A;  3FF3 A;  3O8Z A;  3OAK A;  4NGR A;  3SJX A;  2CIJ A;  5J3X A;  3VRO A;  4A4B A;  1FBV A;  4OC1 A;  3S9N A;  1WJT A;  3BI0 A;  2PVW A;  2XEI A;  1B47 A;  1YVH A;  2XPP A;  1Z8L A;  2OOT A;  3OB2 B;  3VRQ A;  3PT1 A;  3F9K C;  3FED A;  2JBJ A;  4BPU B;  2VKZ G;  3OP0 A;  2PVV A;  4P4J A;  4NGQ A;  4MCS A;  3BUM B;  4W9Y A;  3IWW A;  3BUX B;  4BTF A;  4P4I A;  2OR4 A;  3BUO B;  2CBL A;  3S9M A;  2Y1N A;  5F09 A;  1Z9E A;  3KAS A;  4OC3 A;  4P44 A;  4A4C A;  3VGO A;  4OC5 A;  2XPL A;  4LQG A;  5D29 A;  3D7H A;  3HPG G;  4P4F A;  4P4D A;  4MCR A;  3PLF B;  3U88 C;  4MCQ A;  4OC0 A; 
#chains in the Genus database with same CATH homology
 2XPN A;  2XPL A;  3U88 C;  1Z9E A;  3NFQ A;  2B4J C;  3HPH E;  1WJT A;  3O8Z A;  3OAK A;  1EO0 A;  2XPO A;  3F9K C;  3HPG G;  2XPP A;  2N3A B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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