1Z9EA

Solution structure of the hiv-1 integrase-binding domain in ledgf/p75
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
83
structure length
83
Chain Sequence
SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
pubmed doi rcsb
source organism Homo sapiens
molecule tags Protein binding/transcription
molecule keywords PC4 and SFRS1 interacting protein 2
total genus 24
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2005-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11467 LEDGF Lens epithelium-derived growth factor (LEDGF)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 1z9eA00
2XPPA 2XPOA 1EO0A 2B4JC 1Z9EA 1WJTA 3F9KC 3O8ZA 3OAKA 2XPLA 3HPHE 2N3AB 2XPNA 3U88C 3NFQA 3HPGG
chains in the Genus database with same CATH superfamily
3IWWA 3D7FA 2XEJA 4MCQA 3HMJG 3FEDA 5HKWA 2XEGA 2CIJA 4LQGA 3OAKA 3D7HA 2OOTA 4P45A 2XPNA 3U88C 4P44A 2CBLA 5HKZA 3F9KC 4P4JA 4OMEA 2XPLA 3FECA 4BPUB 3BUMB 2JBKA 3BUWB 2JBJA 4MCRA 2C6GA 3HPGG 3D7DA 2Y1MA 3SJEA 3OB2B 3PT1A 1CX8A 3S9LA 4OC5A 4MCSA 3NFQA 3BUNB 2PVWA 4NGMA 3KASA 2DLAA 3BUOB 4A4CA 2PVVA 4P4FA 3SJFA 5D29A 3SJXA 2C6PA 4OC2A 5J3XA 3PLFB 2XPOA 4NGTA 4NGNA 1WJTA 3BI0A 3FEEA 3VRPA 3OB1B 2N3AB 2UV8G 3O8ZA 3HPHE 1FBVA 2XEIA 3VRQA 2XPPA 3SJGA 3VRRA 3VROA 1Z9EA 4W9YA 3BUXB 4RR2B 4A4BA 4NGQA 3OP0A 4JZ0A 4JYWA 5HKYA 3BI1A 1YVHA 4OC4A 3FF3A 3VRNA 3BHXA 4P4BA 1EO0A 4BPWB 3S9MA 2B4JC 1B47A 2Y1NA 5BY0A 3ZNIA 4OC1A 3D7GA 5ELYA 5AXIA 3S9NA 2OR4A 1DE4C 3RBUA 5F13A 4BTFA 1Z8LA 3BXMA 3VGOA 4BPXB 5F09A 4P4EA 4P4DA 4OC0A 4MCPA 2XEFA 2VKZG 4NGSA 4P4IA 4OC3A 4X3RA 3PFVA 2C6CA 4GPLB 4NGPA 4NGRA
chains in the Genus database with same CATH topology
2XPPA 2XPOA 1EO0A 2B4JC 1Z9EA 1WJTA 3F9KC 3O8ZA 3OAKA 2XPLA 3HPHE 2N3AB 2XPNA 3U88C 3NFQA 3HPGG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XPP A;  2XPO A;  1EO0 A;  2B4J C;  1Z9E A;  1WJT A;  3F9K C;  3O8Z A;  3OAK A;  2XPL A;  3HPH E;  2N3A B;  2XPN A;  3U88 C;  3NFQ A;  3HPG G; 
#chains in the Genus database with same CATH topology
 3IWW A;  3D7F A;  2XEJ A;  4MCQ A;  3HMJ G;  3FED A;  5HKW A;  2XEG A;  2CIJ A;  4LQG A;  3OAK A;  3D7H A;  2OOT A;  4P45 A;  2XPN A;  3U88 C;  4P44 A;  2CBL A;  5HKZ A;  3F9K C;  4P4J A;  4OME A;  2XPL A;  3FEC A;  4BPU B;  3BUM B;  2JBK A;  3BUW B;  2JBJ A;  4MCR A;  2C6G A;  3HPG G;  3D7D A;  2Y1M A;  3SJE A;  3OB2 B;  3PT1 A;  1CX8 A;  3S9L A;  4OC5 A;  4MCS A;  3NFQ A;  3BUN B;  2PVW A;  4NGM A;  3KAS A;  2DLA A;  3BUO B;  4A4C A;  2PVV A;  4P4F A;  3SJF A;  5D29 A;  3SJX A;  2C6P A;  4OC2 A;  5J3X A;  3PLF B;  2XPO A;  4NGT A;  4NGN A;  1WJT A;  3BI0 A;  3FEE A;  3VRP A;  3OB1 B;  2N3A B;  2UV8 G;  3O8Z A;  3HPH E;  1FBV A;  2XEI A;  3VRQ A;  2XPP A;  3SJG A;  3VRR A;  3VRO A;  1Z9E A;  4W9Y A;  3BUX B;  4RR2 B;  4A4B A;  4NGQ A;  3OP0 A;  4JZ0 A;  4JYW A;  5HKY A;  3BI1 A;  1YVH A;  4OC4 A;  3FF3 A;  3VRN A;  3BHX A;  4P4B A;  1EO0 A;  4BPW B;  3S9M A;  2B4J C;  1B47 A;  2Y1N A;  5BY0 A;  3ZNI A;  4OC1 A;  3D7G A;  5ELY A;  5AXI A;  3S9N A;  2OR4 A;  1DE4 C;  3RBU A;  5F13 A;  4BTF A;  1Z8L A;  3BXM A;  3VGO A;  4BPX B;  5F09 A;  4P4E A;  4P4D A;  4OC0 A;  4MCP A;  2XEF A;  2VKZ G;  4NGS A;  4P4I A;  4OC3 A;  4X3R A;  3PFV A;  2C6C A;  4GPL B;  4NGP A;  4NGR A; 
#chains in the Genus database with same CATH homology
 2XPP A;  2XPO A;  1EO0 A;  2B4J C;  1Z9E A;  1WJT A;  3F9K C;  3O8Z A;  3OAK A;  2XPL A;  3HPH E;  2N3A B;  2XPN A;  3U88 C;  3NFQ A;  3HPG G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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