1Z9EA

Solution structure of the hiv-1 integrase-binding domain in ledgf/p75
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
83
structure length
83
Chain Sequence
SMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75
pubmed doi rcsb
molecule keywords PC4 and SFRS1 interacting protein 2
molecule tags Protein binding/transcription
source organism Homo sapiens
total genus 24
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2005-04-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11467 LEDGF Lens epithelium-derived growth factor (LEDGF)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.930.10 Mainly Alpha Up-down Bundle Transcription Elongation Factor S-II; Chain A Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 1z9eA00
3HPHE 3OAKA 2N3AB 3F9KC 3U88C 2XPOA 3NFQA 3HPGG 1EO0A 3O8ZA 2B4JC 1Z9EA 2XPPA 2XPNA 1WJTA 2XPLA
chains in the Genus database with same CATH superfamily
3OB2B 3BI0A 4RR2B 5D29A 5BY0A 5ELYA 2XPNA 3BUNB 3O8ZA 4OMEA 4NGSA 2XEFA 4NGQA 4X3RA 3OP0A 2C6PA 1CX8A 5AXIA 4JYWA 2XPLA 4OC1A 3IWWA 3D7HA 3BI1A 4P4FA 4MCRA 3SJFA 4NGNA 2XPOA 4MCPA 4MCQA 3ZNIA 4P45A 4OC3A 2C6GA 3SJXA 3PT1A 4GPLB 3HPGG 3BUXB 2PVWA 3VGOA 5F13A 4BTFA 3S9NA 3VROA 3BUOB 4P4JA 5F09A 3BHXA 4BPUB 3RBUA 3KASA 1FBVA 2Y1NA 3SJEA 4OC5A 2JBKA 5HKYA 4OC0A 4OC2A 1B47A 2XEIA 1DE4C 2XEJA 4P4EA 4NGPA 3BUWB 3VRRA 4P4BA 3HPHE 2N3AB 4MCSA 4NGRA 3VRQA 4W9YA 2VKZG 3VRNA 3FEEA 3HMJG 3VRPA 2C6CA 2UV8G 3F9KC 2XEGA 2PVVA 1YVHA 3D7DA 3FEDA 2CBLA 5HKWA 1Z9EA 4NGTA 4NGMA 4OC4A 5J3XA 3BUMB 3FF3A 4P4IA 3S9LA 4JZ0A 2XPPA 4A4CA 4LQGA 4P4DA 2CIJA 3SJGA 3FECA 3S9MA 4BPWB 2B4JC 2DLAA 4BPXB 3D7FA 2JBJA 3OAKA 5HKZA 1Z8LA 2OR4A 3BXMA 2OOTA 3PFVA 3D7GA 3U88C 1WJTA 3NFQA 2Y1MA 4A4BA 4P44A 1EO0A 3PLFB 3OB1B
chains in the Genus database with same CATH topology
3HPHE 3OAKA 2N3AB 3F9KC 3U88C 2XPOA 3NFQA 3HPGG 1EO0A 3O8ZA 2B4JC 1Z9EA 2XPPA 2XPNA 1WJTA 2XPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HPH E;  3OAK A;  2N3A B;  3F9K C;  3U88 C;  2XPO A;  3NFQ A;  3HPG G;  1EO0 A;  3O8Z A;  2B4J C;  1Z9E A;  2XPP A;  2XPN A;  1WJT A;  2XPL A; 
#chains in the Genus database with same CATH topology
 3OB2 B;  3BI0 A;  4RR2 B;  5D29 A;  5BY0 A;  5ELY A;  2XPN A;  3BUN B;  3O8Z A;  4OME A;  4NGS A;  2XEF A;  4NGQ A;  4X3R A;  3OP0 A;  2C6P A;  1CX8 A;  5AXI A;  4JYW A;  2XPL A;  4OC1 A;  3IWW A;  3D7H A;  3BI1 A;  4P4F A;  4MCR A;  3SJF A;  4NGN A;  2XPO A;  4MCP A;  4MCQ A;  3ZNI A;  4P45 A;  4OC3 A;  2C6G A;  3SJX A;  3PT1 A;  4GPL B;  3HPG G;  3BUX B;  2PVW A;  3VGO A;  5F13 A;  4BTF A;  3S9N A;  3VRO A;  3BUO B;  4P4J A;  5F09 A;  3BHX A;  4BPU B;  3RBU A;  3KAS A;  1FBV A;  2Y1N A;  3SJE A;  4OC5 A;  2JBK A;  5HKY A;  4OC0 A;  4OC2 A;  1B47 A;  2XEI A;  1DE4 C;  2XEJ A;  4P4E A;  4NGP A;  3BUW B;  3VRR A;  4P4B A;  3HPH E;  2N3A B;  4MCS A;  4NGR A;  3VRQ A;  4W9Y A;  2VKZ G;  3VRN A;  3FEE A;  3HMJ G;  3VRP A;  2C6C A;  2UV8 G;  3F9K C;  2XEG A;  2PVV A;  1YVH A;  3D7D A;  3FED A;  2CBL A;  5HKW A;  1Z9E A;  4NGT A;  4NGM A;  4OC4 A;  5J3X A;  3BUM B;  3FF3 A;  4P4I A;  3S9L A;  4JZ0 A;  2XPP A;  4A4C A;  4LQG A;  4P4D A;  2CIJ A;  3SJG A;  3FEC A;  3S9M A;  4BPW B;  2B4J C;  2DLA A;  4BPX B;  3D7F A;  2JBJ A;  3OAK A;  5HKZ A;  1Z8L A;  2OR4 A;  3BXM A;  2OOT A;  3PFV A;  3D7G A;  3U88 C;  1WJT A;  3NFQ A;  2Y1M A;  4A4B A;  4P44 A;  1EO0 A;  3PLF B;  3OB1 B; 
#chains in the Genus database with same CATH homology
 3HPH E;  3OAK A;  2N3A B;  3F9K C;  3U88 C;  2XPO A;  3NFQ A;  3HPG G;  1EO0 A;  3O8Z A;  2B4J C;  1Z9E A;  2XPP A;  2XPN A;  1WJT A;  2XPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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