1ZB7A

Crystal structure of botulinum neurotoxin type g light chain
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
437
structure length
414
Chain Sequence
PVNIKNFNYNDPINNDDIIMMEPFNDPGPGTYYKAFRIIDRIWIVPERFTYKDVYEYYDPTYLKTDAEKDKFLKTMIKLFNRINSKPSGQRLLDMIVDAIPYLGNASTPPDKFAANVANVSINKKIIQPGAEDQIKGLMTNLIIFGPGPVLSDNFTDSMIMNGHSPISEGFGARMMIRFCPSCLNVFNNVQENKIFSRRAYFADPALTLMHELIHVLHGLYGIKISNLPITPFMQHSDPVQAEELYTFGGHDPSVISPSTDMNIYNKALQNFQDIANRLNIVSSAQGSGIDISLYKQIYKNKYDFVEDPNGKYSVDKDKFDKLYKALMFGFTETNLAGEYGIKTRYSYFSEYLPPIKTEKLLDNTIYTQNEGFNIASKNLKTEFNGQNKAVNKEAYEEISLEHLVIYRIAMCKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of botulinum neurotoxin type g light chain: serotype divergence in substrate recognition
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium botulinum
molecule keywords neurotoxin
total genus 127
structure length 414
sequence length 437
ec nomenclature ec 3.4.24.69: Bontoxilysin.
pdb deposition date 2005-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01742 Peptidase_M27 Clostridial neurotoxin zinc protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.1240.10 Alpha Beta Alpha-Beta Complex Zincin-like Metalloproteases ("zincins"), catalytic domain like 1zb7A00
3K3QB 2ISGA 2G7KA 4EL4A 2A97A 1ZB7A 4KS6A 2XHLA 3V0BA 1ZL6A 3QIZA 3C8AA 2ISHA 2ILPA 3FIEA 3ZUSA 3V0AA 1S0DA 3C8BA 3QW6A 3VUOA 3V0BB 1G9AA 1T3CA 3QJ0A 1T3AA 2W2DA 4EJ5A 3NF3A 3V0AB 1I1EA 2IMCA 1G9DA 4ZJXA 3BONA 4KTXA 3BTAA 1F31A 3BOOA 2IMAA 3BWIA 2QN0A 3QIYA 2NYYA 1S0BA 1ZKWA 1XTFA 3QW7A 2IMBA 3D3XA 4J1LA 3DDAA 2ISEA 3DSEA 3C89A 4ZKTB 3BOKA 3DEBA 2NZ9A 2G7PA 1F82A 1ZN3A 2G7NA 1ZKXA 3ZUQA 5BQNA 1E1HA 2A8AA 5BQMA 1S0GA 4KUFA 3QIXA 3FFZA 1YVGA 3QW8A 4HEVA 3C88A 2ETFA 2G7QA 3ZURA 1Z7HA 3DS9A 1S0EA 3QW5A 3FIIA 1XTGA 1G9CA 1ZL5A 1S0FA 1EPWA 1S0CA 2FPQA 2NP0A 4ELCA 1G9BA 3DDBA
chains in the Genus database with same CATH superfamily
3K3QB 2ISGA 4IL3A 2G7KA 4EL4A 2A97A 1ZB7A 4KS6A 2XHLA 3V0BA 1ZL6A 3QIZA 3C8AA 2ISHA 2ILPA 3FIEA 3ZUSA 3V0AA 1S0DA 3C8BA 3QW6A 3VUOA 3V0BB 1G9AA 1T3CA 3QJ0A 1T3AA 2W2DA 4EJ5A 3NF3A 3V0AB 1I1EA 2IMCA 3E11A 1G9DA 4ZJXA 3BONA 4KTXA 3BTAA 1F31A 3BOOA 2IMAA 3BWIA 2QN0A 3QIYA 2NYYA 1S0BA 1ZKWA 1XTFA 3QW7A 2IMBA 3D3XA 4J1LA 3DDAA 2ISEA 4JIXA 3DSEA 3C89A 4ZKTB 3BOKA 3DEBA 3CQBA 2NZ9A 2G7PA 2YPTA 1F82A 1ZN3A 2G7NA 1ZKXA 2EJQA 3ZUQA 5BQNA 1E1HA 2A8AA 4JIUA 5BQMA 1S0GA 4KUFA 3QIXA 3FFZA 1YVGA 3QW8A 4HEVA 3C88A 2ETFA 4AW6A 2G7QA 3ZURA 1Z7HA 3DS9A 4QHFA 1S0EA 3QW5A 3FIIA 1XTGA 1G9CA 1ZL5A 1S0FA 1EPWA 1S0CA 2FPQA 2NP0A 4ELCA 1G9BA 3DDBA
chains in the Genus database with same CATH topology
3K3QB 2ISGA 2G7KA 4EL4A 2A97A 1ZB7A 4KS6A 2XHLA 3V0BA 1ZL6A 3QIZA 3C8AA 2ISHA 2ILPA 3FIEA 3ZUSA 3V0AA 1S0DA 3C8BA 3QW6A 3VUOA 3V0BB 1G9AA 1T3CA 3QJ0A 1T3AA 2W2DA 4EJ5A 3NF3A 3V0AB 1I1EA 2IMCA 1G9DA 4ZJXA 3BONA 4KTXA 3BTAA 1F31A 3BOOA 2IMAA 3BWIA 2QN0A 3QIYA 2NYYA 1S0BA 1ZKWA 1XTFA 3QW7A 2IMBA 3D3XA 4J1LA 3DDAA 2ISEA 3DSEA 3C89A 4ZKTB 3BOKA 3DEBA 2NZ9A 2G7PA 1F82A 1ZN3A 2G7NA 1ZKXA 3ZUQA 5BQNA 1E1HA 2A8AA 5BQMA 1S0GA 4KUFA 3QIXA 3FFZA 1YVGA 3QW8A 4HEVA 3C88A 2ETFA 2G7QA 3ZURA 1Z7HA 3DS9A 1S0EA 3QW5A 3FIIA 1XTGA 1G9CA 1ZL5A 1S0FA 1EPWA 1S0CA 2FPQA 2NP0A 4ELCA 1G9BA 3DDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K3Q B;  2ISG A;  2G7K A;  4EL4 A;  2A97 A;  1ZB7 A;  4KS6 A;  2XHL A;  3V0B A;  1ZL6 A;  3QIZ A;  3C8A A;  2ISH A;  2ILP A;  3FIE A;  3ZUS A;  3V0A A;  1S0D A;  3C8B A;  3QW6 A;  3VUO A;  3V0B B;  1G9A A;  1T3C A;  3QJ0 A;  1T3A A;  2W2D A;  4EJ5 A;  3NF3 A;  3V0A B;  1I1E A;  2IMC A;  1G9D A;  4ZJX A;  3BON A;  4KTX A;  3BTA A;  1F31 A;  3BOO A;  2IMA A;  3BWI A;  2QN0 A;  3QIY A;  2NYY A;  1S0B A;  1ZKW A;  1XTF A;  3QW7 A;  2IMB A;  3D3X A;  4J1L A;  3DDA A;  2ISE A;  3DSE A;  3C89 A;  4ZKT B;  3BOK A;  3DEB A;  2NZ9 A;  2G7P A;  1F82 A;  1ZN3 A;  2G7N A;  1ZKX A;  3ZUQ A;  5BQN A;  1E1H A;  2A8A A;  5BQM A;  1S0G A;  4KUF A;  3QIX A;  3FFZ A;  1YVG A;  3QW8 A;  4HEV A;  3C88 A;  2ETF A;  2G7Q A;  3ZUR A;  1Z7H A;  3DS9 A;  1S0E A;  3QW5 A;  3FII A;  1XTG A;  1G9C A;  1ZL5 A;  1S0F A;  1EPW A;  1S0C A;  2FPQ A;  2NP0 A;  4ELC A;  1G9B A;  3DDB A; 
#chains in the Genus database with same CATH topology
 3K3Q B;  2ISG A;  4IL3 A;  2G7K A;  4EL4 A;  2A97 A;  1ZB7 A;  4KS6 A;  2XHL A;  3V0B A;  1ZL6 A;  3QIZ A;  3C8A A;  2ISH A;  2ILP A;  3FIE A;  3ZUS A;  3V0A A;  1S0D A;  3C8B A;  3QW6 A;  3VUO A;  3V0B B;  1G9A A;  1T3C A;  3QJ0 A;  1T3A A;  2W2D A;  4EJ5 A;  3NF3 A;  3V0A B;  1I1E A;  2IMC A;  3E11 A;  1G9D A;  4ZJX A;  3BON A;  4KTX A;  3BTA A;  1F31 A;  3BOO A;  2IMA A;  3BWI A;  2QN0 A;  3QIY A;  2NYY A;  1S0B A;  1ZKW A;  1XTF A;  3QW7 A;  2IMB A;  3D3X A;  4J1L A;  3DDA A;  2ISE A;  4JIX A;  3DSE A;  3C89 A;  4ZKT B;  3BOK A;  3DEB A;  3CQB A;  2NZ9 A;  2G7P A;  2YPT A;  1F82 A;  1ZN3 A;  2G7N A;  1ZKX A;  2EJQ A;  3ZUQ A;  5BQN A;  1E1H A;  2A8A A;  4JIU A;  5BQM A;  1S0G A;  4KUF A;  3QIX A;  3FFZ A;  1YVG A;  3QW8 A;  4HEV A;  3C88 A;  2ETF A;  4AW6 A;  2G7Q A;  3ZUR A;  1Z7H A;  3DS9 A;  4QHF A;  1S0E A;  3QW5 A;  3FII A;  1XTG A;  1G9C A;  1ZL5 A;  1S0F A;  1EPW A;  1S0C A;  2FPQ A;  2NP0 A;  4ELC A;  1G9B A;  3DDB A; 
#chains in the Genus database with same CATH homology
 3K3Q B;  2ISG A;  2G7K A;  4EL4 A;  2A97 A;  1ZB7 A;  4KS6 A;  2XHL A;  3V0B A;  1ZL6 A;  3QIZ A;  3C8A A;  2ISH A;  2ILP A;  3FIE A;  3ZUS A;  3V0A A;  1S0D A;  3C8B A;  3QW6 A;  3VUO A;  3V0B B;  1G9A A;  1T3C A;  3QJ0 A;  1T3A A;  2W2D A;  4EJ5 A;  3NF3 A;  3V0A B;  1I1E A;  2IMC A;  1G9D A;  4ZJX A;  3BON A;  4KTX A;  3BTA A;  1F31 A;  3BOO A;  2IMA A;  3BWI A;  2QN0 A;  3QIY A;  2NYY A;  1S0B A;  1ZKW A;  1XTF A;  3QW7 A;  2IMB A;  3D3X A;  4J1L A;  3DDA A;  2ISE A;  3DSE A;  3C89 A;  4ZKT B;  3BOK A;  3DEB A;  2NZ9 A;  2G7P A;  1F82 A;  1ZN3 A;  2G7N A;  1ZKX A;  3ZUQ A;  5BQN A;  1E1H A;  2A8A A;  5BQM A;  1S0G A;  4KUF A;  3QIX A;  3FFZ A;  1YVG A;  3QW8 A;  4HEV A;  3C88 A;  2ETF A;  2G7Q A;  3ZUR A;  1Z7H A;  3DS9 A;  1S0E A;  3QW5 A;  3FII A;  1XTG A;  1G9C A;  1ZL5 A;  1S0F A;  1EPW A;  1S0C A;  2FPQ A;  2NP0 A;  4ELC A;  1G9B A;  3DDB A; 
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similar chains in the Genus database (?% sequence similarity)
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