1ZC0A

Crystal structure of human hematopoietic tyrosine phosphatase (heptp) catalytic domain
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
290
structure length
286
Chain Sequence
TPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRECVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase, non-receptor type 7
total genus 95
structure length 286
sequence length 290
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2005-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1zc0A00
5KABA 1L8KA 2B4PA 4ZN5A 3S4EA 2GP0A 1C86A 3SMEA 1Q6NA 1Q1MA 2DXPA 2QBSA 1ZC0A 2SHPA 3RZ2A 1Q6JA 4YR8B 1QXKA 3ZV2A 2OOQA 1T49A 5KA4A 2QCJA 1YZ4A 3OLRA 1I9SA 2J16B 2G59A 3I80A 2BV5A 2F6WA 1FPZA 1D5RA 2I3UA 4JBCA 5BZZA 1G4US 2QDMA 3QCMA 5I6VA 1NWLA 1G1FA 3S4OA 4GWFA 1I57A 2F6TA 4R0TA 4MBBA 2CNIA 2E0TA 1ZCLA 1XXPA 1PH0A 2NZ6A 3A5JA 1YWFA 3EU0A 3ZMPA 2ZN7A 5KADA 1OHDA 3MMJA 1JLNA 4ZRTA 4HRFA 2CJZA 4IKCA 2CM3A 3QCDA 2HNQA 3H2XA 4WU2A 2Q47A 2F6YA 2QDCA 4TVVA 2P6XA 4OHDA 5KA0A 3QCCA 2CNFA 3QCBA 3OMHA 2BGEA 2I6IA 2B4OA 2Q05A 2Y96A 3BRHA 2I3RA 3PS5A 4RH9A 1NNYA 2GWOA 4ICZA 3S3KA 4S0GA 1Q6TA 1PTTA 2HCMA 2RF6A 3O3LA 3QCLA 2NLKA 3ZMQA 2F6VA 4NNDA 1J4XA 1Q6PA 4QUNA 2ZMMA 1ZZWA 1SUGA 2I4EA 2I4GA 2PA5A 3QCNA 4PYHA 4I8NA 2B07A 1L8GA 2QCTA 3O5XA 1VHRA 3D1QA 2FJNA 2JJDA 4KI9A 1FPRA 3AWEA 3I7ZA 2VEXA 4GE2A 2OZ5A 2R0BA 5BX1A 3O4SA 4QAHA 1LARA 3O4TA 1EEOA 4NX8A 3D42A 3QCFA 4OHHA 2PQ5A 3QCHA 4H34A 3V0HA 1I9TA 2F6FA 1OHEA 3GXGA 3S3EA 4QBEA 4GRYA 5IBSA 4HJQA 5KACA 4GS0A 1PA1A 2FJMA 3MOZA 5GTJA 4JMKA 4GE5A 2CMCA 4B04A 4RHGA 2F70A 5KA3A 3SR9A 1G1HA 4DGPA 1OEMX 1XRIA 1R6HA 4PVGA 1KAKA 2B3OA 3QCGA 1RPMA 2I75A 3F9AA 1C84A 3V0EA 4RI4A 3ZM0A 3D1HA 1GFYA 2HC2A 2I6MA 2CMAA 1X24A 3F81A 4AZ1A 2ESBA 1OEUA 1BZCA 3BLUA 4QAPA 1G7FA 2I6PA 4BPCA 3F99A 2I4HA 3RO1A 1C85A 2AHSA 2I42A 1KAVA 3M4UA 2PSZA 4KYRA 2IMGA 1PTYA 5MMZB 2C7SA 4GFVA 4Y14A 2HVLA 3ZM1A 3CM3A 2F6ZA 3N0AA 5LXQB 4RH5A 2CMBA 2QBRA 4RKKA 4R30A 2HC1A 4NYHA 5K24A 2F71A 5KA9A 3QKPA 5HDEA 1A5YA 2YDUA 1OESA 1ECVA 1T4JA 3O4UA 3EAXA 3QCIA 2HB1A 2CNEA 5K9VA 1PTUA 1U26A 2GJTA 3ZM3A 4OHLA 4NWFA 3U96A 1FQ1A 3V0JA 3EMUA 4JNBA 5J8RA 2CM7A 3RGQA 3QCEA 4BJOA 1AAXA 1PYNA 5KA7A 2I1YA 3AWFA 4KYQA 4OHEA 2QBQA 1JF7A 5K23A 1NO6A 2B4UA 1OETA 1V3AA 2Y2FA 3EB1A 4ERCA 2NT7A 1XXVA 4JMJA 1NWEA 4J51A 5KAAA 5KA2A 3V0FA 3V0IA 3QCKA 1T48A 3BLTA 5IBMA 1PXHA 2VEUA 2C46A 3A5KA 1EENA 3I36A 1YN9A 1C88A 4QUMA 2J16A 2PBNA 4Z6BA 1NZ7A 2HY3A 4D3QA 1ONYA 1ONZA 1C87A 2MBCA 2QEPA 2I5XA 1OEOX 3AWGA 3NMEA 4NWGA 2B49A 5KA1A 2BIJA 4D3RA 4RDDA 1U25A 4WU3A 3EZZA 1LQFA 4Y2EA 3RGOA 1G7GA 2OC3A 4GRZA 2HNPA 4RI5A 3V0GA 2H4VA 3D9CA 2VEYA 2G6ZA 1MKPA 4OHIA 3D1OA 2A3KA 4GFUA 2CNHA 5KA8A 1G4WR 2NT2A 2BGDA 2VEVA 4ZI4A 5K25A 2OUDA 2H02A 5AWXA 3BM8A 5BZXA 4QBWA 4R0SA 1GWZA 1NL9A 1YPTA 5EHPA 1YTSA 1PTVA 3B7OA 2F46A 3QCJA 1XBOA 3S3HA 1WCHA 1YGUA 1OEVA 2H03A 2NTAA 1PA9A 1Q6SA 1U24A 3F9BA 4YAAA 2NV5A 1WRMA 4DGXA 2VEWA 2CFVA 1YGRA 2I6JA 2M3VA 2B4SA 4WOHA 2PT0A 4D3PA 1G1GA 1OHCA 1ZCKA 1BZJA 2CNGA 1P15A 2A8BA 2QDPA 2H04A 5K9WA 3MOWA 5K22A 1QZ0A 1C83A 3CWEA 2H4KA 3D44A 2I6OA 3S3FA 2P4DA 1BZHA 1M3GA 5EHRA 4WTYA 1LYVA 3LJ8A 3V0DA 2H4GA 1YTWA 2PI7A 2FH7A 1Q6MA 1WAXA 3F41A 3QKQA 5BUGA 3GXHA 1YFOA 1XM2A 2HXPA 2BZLA 2J17A 2CM8A 1RXDA 4HJPA 4H1OA 2QBPA 2WGPA 5M43A 1YTNA 2AZRA 2CM2A 4GE6A 3ZM2A
chains in the Genus database with same CATH superfamily
5KABA 1L8KA 2B4PA 4ZN5A 3S4EA 2GP0A 1C86A 1E8CA 3SMEA 1Q6NA 1Q1MA 2DXPA 2QBSA 1ZC0A 2SHPA 3RZ2A 1Q6JA 4BUBA 1QXKA 4BUCA 4YR8B 3ZV2A 2OOQA 1T49A 2X5OA 5KA4A 2QCJA 1YZ4A 3OLRA 1I9SA 2J16B 2G59A 3I80A 2BV5A 2F6WA 1FPZA 1D5RA 2I3UA 1GQYA 4JBCA 5BZZA 1G4US 1JBVA 2QDMA 3QCMA 5I6VA 1NWLA 1G1FA 3S4OA 1E0DA 4GWFA 1W7KA 1I57A 2F6TA 4R0TA 4MBBA 2CNIA 2E0TA 1ZCLA 1XXPA 1PH0A 2Y68A 2VTDA 2NZ6A 3A5JA 1YWFA 3EU0A 3ZMPA 2ZN7A 5KADA 4QDIA 1OHDA 3MMJA 2Y67A 1JLNA 4ZRTA 4HRFA 2CJZA 4IKCA 2CM3A 2XJAA 3NRSA 3QCDA 2HNQA 1J6UA 3H2XA 4WU2A 2GCBA 2Q47A 4UAGA 2F6YA 2QDCA 4TVVA 2P6XA 4OHDA 5KA0A 3QCCA 4QF5A 2CNFA 3QCBA 3OMHA 2BGEA 2I6IA 2B4OA 2Q05A 2Y96A 3BRHA 1W78A 2I3RA 3PS5A 4RH9A 1NNYA 2GWOA 4ICZA 3S3KA 4S0GA 1Q6TA 1PTTA 2HCMA 1UAGA 2RF6A 3O3LA 3QCLA 2NLKA 3ZMQA 2F6VA 4NNDA 1J4XA 1Q6PA 4QUNA 2ZMMA 1ZZWA 1SUGA 2I4EA 2I4GA 2PA5A 3QCNA 2GC5A 3HN7A 4PYHA 4I8NA 5A5EA 2B07A 1L8GA 2QCTA 3O5XA 1VHRA 3D1QA 3ZM2A 2FJNA 2JJDA 4KI9A 1FPRA 3AWEA 3I7ZA 2VEXA 4GE2A 2OZ5A 2R0BA 5BX1A 3O4SA 4QAHA 1LARA 3O4TA 2XPCA 1EEOA 4NX8A 3D42A 2F00A 3QCFA 4OHHA 2PQ5A 3QCHA 3QCZA 4H34A 1I9TA 3V0HA 2F6FA 1OHEA 3GXGA 2Y66A 3S3EA 2WJPA 4QBEA 4GRYA 5IBSA 4HJQA 5KACA 4GS0A 1PA1A 2FJMA 3MOZA 5GTJA 4JMKA 4GE5A 1FGSA 2CMCA 4B04A 4RHGA 2F70A 5KA3A 3SR9A 1G1HA 3UAGA 4DGPA 1OEMX 1XRIA 1R6HA 4PVGA 1KAKA 2B3OA 3QCGA 1RPMA 2I75A 3F9AA 1C84A 3N2AA 3V0EA 3MVNA 4RI4A 3ZM0A 3D1HA 1GFYA 2HC2A 2I6MA 2CMAA 1X24A 3F81A 4AZ1A 2ESBA 1OEUA 1JBWA 4C12A 1BZCA 3BLUA 4QAPA 1G7FA 2I6PA 4BPCA 2UUOA 2I4HA 3F99A 3RO1A 1C85A 2AHSA 2I42A 1KAVA 2VORA 3M4UA 2PSZA 4KYRA 2IMGA 1PTYA 5MMZB 2C7SA 4GFVA 4Y14A 2HVLA 3ZM1A 3CM3A 2F6ZA 3N0AA 5LXQB 4RH5A 2UUPA 2CMBA 2QBRA 4RKKA 2UAGA 4R30A 2HC1A 4NYHA 5K24A 2F71A 5KA9A 3QKPA 5HDEA 4ZIYA 1A5YA 2YDUA 1OESA 1ECVA 1T4JA 3O4UA 3EAXA 3QCIA 2HB1A 2CNEA 5K9VA 1PTUA 1U26A 3PYZA 2GJTA 3ZM3A 2AM2A 4OHLA 4NWFA 3U96A 1FQ1A 3V0JA 3EMUA 4JNBA 5J8RA 2CM7A 3RGQA 3QCEA 1P31A 4BJOA 1AAXA 2GC6A 1PYNA 2WTZA 5KA7A 2I1YA 3AWFA 4KYQA 4OHEA 2QBQA 1JF7A 5K23A 1NO6A 2B4UA 1GQQA 1OETA 1V3AA 2Y2FA 3EB1A 4ERCA 2NT7A 4C13A 1XXVA 4JMJA 3ZL8A 1NWEA 4J51A 5KAAA 5KA2A 3ZM5A 3V0FA 3V0IA 3QCKA 1T48A 5A5FA 3BLTA 5IBMA 1PXHA 2VEUA 2C46A 3A5KA 1EENA 3I36A 1YN9A 1C88A 4QUMA 2J16A 2PBNA 1EEHA 1NZ7A 2HY3A 4Z6BA 4D3QA 1ONYA 1ONZA 1C87A 2MBCA 2QEPA 2I5XA 2Y1OA 1OEOX 3AWGA 3NMEA 4NWGA 2B49A 3ZM6A 2BIJA 4D3RA 4HV4A 4RDDA 5KA1A 1U25A 4CVKA 4WU3A 3EZZA 1LQFA 4Y2EA 3RGOA 1G7GA 2OC3A 4GRZA 2HNPA 4RI5A 3V0GA 2H4VA 3D9CA 2VEYA 2G6ZA 1MKPA 4OHIA 3D1OA 2A3KA 4GFUA 2CNHA 2JFHA 5KA8A 1G4WR 2NT2A 2BGDA 2VEVA 4ZI4A 5K25A 2OUDA 2H02A 5AWXA 2VTEA 3BM8A 2VOSA 5BZXA 4QBWA 4R0SA 1GWZA 1NL9A 1YPTA 5EHPA 1YTSA 1PTVA 3B7OA 2F46A 3QCJA 1XBOA 3S3HA 1WCHA 1YGUA 1OEVA 2H03A 2NTAA 1PA9A 1Q6SA 1U24A 3F9BA 4YAAA 2NV5A 1WRMA 4DGXA 2VEWA 2GCAA 2CFVA 1YGRA 2I6JA 2M3VA 2B4SA 4WOHA 2PT0A 4D3PA 1G1GA 1OHCA 1ZCKA 2AM1A 1BZJA 2CNGA 1P15A 2A8BA 2QDPA 4CVLA 2H04A 5K9WA 3MOWA 5K22A 1QZ0A 1C83A 3CWEA 2H4KA 3D44A 2I6OA 3S3FA 2P4DA 1BZHA 1M3GA 5EHRA 4WTYA 1LYVA 3LJ8A 3V0DA 2H4GA 1YTWA 2PI7A 3LK7A 2FH7A 4CVMA 1Q6MA 1WAXA 3F41A 2JFFA 3QKQA 5BUGA 3GXHA 1YFOA 1XM2A 2HXPA 1GG4A 2BZLA 2J17A 2CM8A 1RXDA 4HJPA 1O5ZA 1P3DA 4H1OA 2QBPA 2WGPA 5M43A 1YTNA 2AZRA 2CM2A 4GE6A 2JFGA
chains in the Genus database with same CATH topology
5KABA 1L8KA 2B4PA 4ZN5A 3S4EA 2GP0A 1C86A 3SMEA 1Q6NA 1Q1MA 2DXPA 2QBSA 1ZC0A 2SHPA 3RZ2A 1Q6JA 4YR8B 1QXKA 3ZV2A 2OOQA 1T49A 5KA4A 2QCJA 1YZ4A 3OLRA 1I9SA 2J16B 2G59A 3I80A 2BV5A 2F6WA 1FPZA 1D5RA 2I3UA 4JBCA 5BZZA 1G4US 2QDMA 3QCMA 5I6VA 1NWLA 1G1FA 3S4OA 4GWFA 1I57A 2F6TA 4R0TA 4MBBA 2CNIA 2E0TA 1ZCLA 1XXPA 1PH0A 2NZ6A 3A5JA 1YWFA 3EU0A 3ZMPA 2ZN7A 5KADA 1OHDA 3MMJA 1JLNA 4ZRTA 4HRFA 2CJZA 4IKCA 2CM3A 3QCDA 2HNQA 3H2XA 4WU2A 2Q47A 2F6YA 2QDCA 4TVVA 2P6XA 4OHDA 5KA0A 3QCCA 2CNFA 3QCBA 3OMHA 2BGEA 2I6IA 2B4OA 2Q05A 2Y96A 3BRHA 2I3RA 3PS5A 4RH9A 1NNYA 2GWOA 4ICZA 3S3KA 4S0GA 1Q6TA 1PTTA 2HCMA 2RF6A 3O3LA 3QCLA 2NLKA 3ZMQA 2F6VA 4NNDA 1J4XA 1Q6PA 4QUNA 2ZMMA 1ZZWA 1SUGA 2I4EA 2I4GA 2PA5A 3QCNA 4PYHA 4I8NA 2B07A 1L8GA 2QCTA 3O5XA 1VHRA 3D1QA 2FJNA 2JJDA 4KI9A 1FPRA 3AWEA 3I7ZA 2VEXA 4GE2A 2OZ5A 2R0BA 5BX1A 3O4SA 4QAHA 1LARA 3O4TA 1EEOA 4NX8A 3D42A 3QCFA 4OHHA 2PQ5A 3QCHA 4H34A 3V0HA 1I9TA 2F6FA 1OHEA 3GXGA 3S3EA 4QBEA 4GRYA 5IBSA 4HJQA 5KACA 4GS0A 1PA1A 2FJMA 3MOZA 5GTJA 4JMKA 4GE5A 2CMCA 4B04A 4RHGA 2F70A 5KA3A 3SR9A 1G1HA 4DGPA 1OEMX 1XRIA 1R6HA 4PVGA 1KAKA 2B3OA 3QCGA 1RPMA 2I75A 3F9AA 1C84A 3V0EA 4RI4A 3ZM0A 3D1HA 1GFYA 2HC2A 2I6MA 2CMAA 1X24A 3F81A 4AZ1A 2ESBA 1OEUA 1BZCA 3BLUA 4QAPA 1G7FA 2I6PA 4BPCA 3F99A 2I4HA 3RO1A 1C85A 2AHSA 2I42A 1KAVA 3M4UA 2PSZA 4KYRA 2IMGA 1PTYA 5MMZB 2C7SA 4GFVA 4Y14A 2HVLA 3ZM1A 3CM3A 2F6ZA 3N0AA 5LXQB 4RH5A 2CMBA 2QBRA 4RKKA 4R30A 2HC1A 4NYHA 5K24A 2F71A 5KA9A 3QKPA 5HDEA 1A5YA 2YDUA 1OESA 1ECVA 1T4JA 3O4UA 3EAXA 3QCIA 2HB1A 2CNEA 5K9VA 1PTUA 1U26A 2GJTA 3ZM3A 4OHLA 4NWFA 3U96A 1FQ1A 3V0JA 3EMUA 4JNBA 5J8RA 2CM7A 3RGQA 3QCEA 4BJOA 1AAXA 1PYNA 5KA7A 2I1YA 3AWFA 4KYQA 4OHEA 2QBQA 1JF7A 5K23A 1NO6A 2B4UA 1OETA 1V3AA 2Y2FA 3EB1A 4ERCA 2NT7A 1XXVA 4JMJA 1NWEA 4J51A 5KAAA 5KA2A 3V0FA 3V0IA 3QCKA 1T48A 3BLTA 5IBMA 1PXHA 2VEUA 2C46A 3A5KA 1EENA 3I36A 1YN9A 1C88A 4QUMA 2J16A 2PBNA 4Z6BA 1NZ7A 2HY3A 4D3QA 1ONYA 1ONZA 1C87A 2MBCA 2QEPA 2I5XA 1OEOX 3AWGA 3NMEA 4NWGA 2B49A 5KA1A 2BIJA 4D3RA 4RDDA 1U25A 4WU3A 3EZZA 1LQFA 4Y2EA 3RGOA 1G7GA 2OC3A 4GRZA 2HNPA 4RI5A 3V0GA 2H4VA 3D9CA 2VEYA 2G6ZA 1MKPA 4OHIA 3D1OA 2A3KA 4GFUA 2CNHA 5KA8A 1G4WR 2NT2A 2BGDA 2VEVA 4ZI4A 5K25A 2OUDA 2H02A 5AWXA 3BM8A 5BZXA 4QBWA 4R0SA 1GWZA 1NL9A 1YPTA 5EHPA 1YTSA 1PTVA 3B7OA 2F46A 3QCJA 1XBOA 3S3HA 1WCHA 1YGUA 1OEVA 2H03A 2NTAA 1PA9A 1Q6SA 1U24A 3F9BA 4YAAA 2NV5A 1WRMA 4DGXA 2VEWA 2CFVA 1YGRA 2I6JA 2M3VA 2B4SA 4WOHA 2PT0A 4D3PA 1G1GA 1OHCA 1ZCKA 1BZJA 2CNGA 1P15A 2A8BA 2QDPA 2H04A 5K9WA 3MOWA 5K22A 1QZ0A 1C83A 3CWEA 2H4KA 3D44A 2I6OA 3S3FA 2P4DA 1BZHA 1M3GA 5EHRA 4WTYA 1LYVA 3LJ8A 3V0DA 2H4GA 1YTWA 2PI7A 2FH7A 1Q6MA 1WAXA 3F41A 3QKQA 5BUGA 3GXHA 1YFOA 1XM2A 2HXPA 2BZLA 2J17A 2CM8A 1RXDA 4HJPA 4H1OA 2QBPA 2WGPA 5M43A 1YTNA 2AZRA 2CM2A 4GE6A 3ZM2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KAB A;  1L8K A;  2B4P A;  4ZN5 A;  3S4E A;  2GP0 A;  1C86 A;  3SME A;  1Q6N A;  1Q1M A;  2DXP A;  2QBS A;  1ZC0 A;  2SHP A;  3RZ2 A;  1Q6J A;  4YR8 B;  1QXK A;  3ZV2 A;  2OOQ A;  1T49 A;  5KA4 A;  2QCJ A;  1YZ4 A;  3OLR A;  1I9S A;  2J16 B;  2G59 A;  3I80 A;  2BV5 A;  2F6W A;  1FPZ A;  1D5R A;  2I3U A;  4JBC A;  5BZZ A;  1G4U S;  2QDM A;  3QCM A;  5I6V A;  1NWL A;  1G1F A;  3S4O A;  4GWF A;  1I57 A;  2F6T A;  4R0T A;  4MBB A;  2CNI A;  2E0T A;  1ZCL A;  1XXP A;  1PH0 A;  2NZ6 A;  3A5J A;  1YWF A;  3EU0 A;  3ZMP A;  2ZN7 A;  5KAD A;  1OHD A;  3MMJ A;  1JLN A;  4ZRT A;  4HRF A;  2CJZ A;  4IKC A;  2CM3 A;  3QCD A;  2HNQ A;  3H2X A;  4WU2 A;  2Q47 A;  2F6Y A;  2QDC A;  4TVV A;  2P6X A;  4OHD A;  5KA0 A;  3QCC A;  2CNF A;  3QCB A;  3OMH A;  2BGE A;  2I6I A;  2B4O A;  2Q05 A;  2Y96 A;  3BRH A;  2I3R A;  3PS5 A;  4RH9 A;  1NNY A;  2GWO A;  4ICZ A;  3S3K A;  4S0G A;  1Q6T A;  1PTT A;  2HCM A;  2RF6 A;  3O3L A;  3QCL A;  2NLK A;  3ZMQ A;  2F6V A;  4NND A;  1J4X A;  1Q6P A;  4QUN A;  2ZMM A;  1ZZW A;  1SUG A;  2I4E A;  2I4G A;  2PA5 A;  3QCN A;  4PYH A;  4I8N A;  2B07 A;  1L8G A;  2QCT A;  3O5X A;  1VHR A;  3D1Q A;  2FJN A;  2JJD A;  4KI9 A;  1FPR A;  3AWE A;  3I7Z A;  2VEX A;  4GE2 A;  2OZ5 A;  2R0B A;  5BX1 A;  3O4S A;  4QAH A;  1LAR A;  3O4T A;  1EEO A;  4NX8 A;  3D42 A;  3QCF A;  4OHH A;  2PQ5 A;  3QCH A;  4H34 A;  3V0H A;  1I9T A;  2F6F A;  1OHE A;  3GXG A;  3S3E A;  4QBE A;  4GRY A;  5IBS A;  4HJQ A;  5KAC A;  4GS0 A;  1PA1 A;  2FJM A;  3MOZ A;  5GTJ A;  4JMK A;  4GE5 A;  2CMC A;  4B04 A;  4RHG A;  2F70 A;  5KA3 A;  3SR9 A;  1G1H A;  4DGP A;  1OEM X;  1XRI A;  1R6H A;  4PVG A;  1KAK A;  2B3O A;  3QCG A;  1RPM A;  2I75 A;  3F9A A;  1C84 A;  3V0E A;  4RI4 A;  3ZM0 A;  3D1H A;  1GFY A;  2HC2 A;  2I6M A;  2CMA A;  1X24 A;  3F81 A;  4AZ1 A;  2ESB A;  1OEU A;  1BZC A;  3BLU A;  4QAP A;  1G7F A;  2I6P A;  4BPC A;  3F99 A;  2I4H A;  3RO1 A;  1C85 A;  2AHS A;  2I42 A;  1KAV A;  3M4U A;  2PSZ A;  4KYR A;  2IMG A;  1PTY A;  5MMZ B;  2C7S A;  4GFV A;  4Y14 A;  2HVL A;  3ZM1 A;  3CM3 A;  2F6Z A;  3N0A A;  5LXQ B;  4RH5 A;  2CMB A;  2QBR A;  4RKK A;  4R30 A;  2HC1 A;  4NYH A;  5K24 A;  2F71 A;  5KA9 A;  3QKP A;  5HDE A;  1A5Y A;  2YDU A;  1OES A;  1ECV A;  1T4J A;  3O4U A;  3EAX A;  3QCI A;  2HB1 A;  2CNE A;  5K9V A;  1PTU A;  1U26 A;  2GJT A;  3ZM3 A;  4OHL A;  4NWF A;  3U96 A;  1FQ1 A;  3V0J A;  3EMU A;  4JNB A;  5J8R A;  2CM7 A;  3RGQ A;  3QCE A;  4BJO A;  1AAX A;  1PYN A;  5KA7 A;  2I1Y A;  3AWF A;  4KYQ A;  4OHE A;  2QBQ A;  1JF7 A;  5K23 A;  1NO6 A;  2B4U A;  1OET A;  1V3A A;  2Y2F A;  3EB1 A;  4ERC A;  2NT7 A;  1XXV A;  4JMJ A;  1NWE A;  4J51 A;  5KAA A;  5KA2 A;  3V0F A;  3V0I A;  3QCK A;  1T48 A;  3BLT A;  5IBM A;  1PXH A;  2VEU A;  2C46 A;  3A5K A;  1EEN A;  3I36 A;  1YN9 A;  1C88 A;  4QUM A;  2J16 A;  2PBN A;  4Z6B A;  1NZ7 A;  2HY3 A;  4D3Q A;  1ONY A;  1ONZ A;  1C87 A;  2MBC A;  2QEP A;  2I5X A;  1OEO X;  3AWG A;  3NME A;  4NWG A;  2B49 A;  5KA1 A;  2BIJ A;  4D3R A;  4RDD A;  1U25 A;  4WU3 A;  3EZZ A;  1LQF A;  4Y2E A;  3RGO A;  1G7G A;  2OC3 A;  4GRZ A;  2HNP A;  4RI5 A;  3V0G A;  2H4V A;  3D9C A;  2VEY A;  2G6Z A;  1MKP A;  4OHI A;  3D1O A;  2A3K A;  4GFU A;  2CNH A;  5KA8 A;  1G4W R;  2NT2 A;  2BGD A;  2VEV A;  4ZI4 A;  5K25 A;  2OUD A;  2H02 A;  5AWX A;  3BM8 A;  5BZX A;  4QBW A;  4R0S A;  1GWZ A;  1NL9 A;  1YPT A;  5EHP A;  1YTS A;  1PTV A;  3B7O A;  2F46 A;  3QCJ A;  1XBO A;  3S3H A;  1WCH A;  1YGU A;  1OEV A;  2H03 A;  2NTA A;  1PA9 A;  1Q6S A;  1U24 A;  3F9B A;  4YAA A;  2NV5 A;  1WRM A;  4DGX A;  2VEW A;  2CFV A;  1YGR A;  2I6J A;  2M3V A;  2B4S A;  4WOH A;  2PT0 A;  4D3P A;  1G1G A;  1OHC A;  1ZCK A;  1BZJ A;  2CNG A;  1P15 A;  2A8B A;  2QDP A;  2H04 A;  5K9W A;  3MOW A;  5K22 A;  1QZ0 A;  1C83 A;  3CWE A;  2H4K A;  3D44 A;  2I6O A;  3S3F A;  2P4D A;  1BZH A;  1M3G A;  5EHR A;  4WTY A;  1LYV A;  3LJ8 A;  3V0D A;  2H4G A;  1YTW A;  2PI7 A;  2FH7 A;  1Q6M A;  1WAX A;  3F41 A;  3QKQ A;  5BUG A;  3GXH A;  1YFO A;  1XM2 A;  2HXP A;  2BZL A;  2J17 A;  2CM8 A;  1RXD A;  4HJP A;  4H1O A;  2QBP A;  2WGP A;  5M43 A;  1YTN A;  2AZR A;  2CM2 A;  4GE6 A;  3ZM2 A; 
#chains in the Genus database with same CATH topology
 5KAB A;  1L8K A;  2B4P A;  4ZN5 A;  3S4E A;  2GP0 A;  1C86 A;  1E8C A;  3SME A;  1Q6N A;  1Q1M A;  2DXP A;  2QBS A;  1ZC0 A;  2SHP A;  3RZ2 A;  1Q6J A;  4BUB A;  1QXK A;  4BUC A;  4YR8 B;  3ZV2 A;  2OOQ A;  1T49 A;  2X5O A;  5KA4 A;  2QCJ A;  1YZ4 A;  3OLR A;  1I9S A;  2J16 B;  2G59 A;  3I80 A;  2BV5 A;  2F6W A;  1FPZ A;  1D5R A;  2I3U A;  1GQY A;  4JBC A;  5BZZ A;  1G4U S;  1JBV A;  2QDM A;  3QCM A;  5I6V A;  1NWL A;  1G1F A;  3S4O A;  1E0D A;  4GWF A;  1W7K A;  1I57 A;  2F6T A;  4R0T A;  4MBB A;  2CNI A;  2E0T A;  1ZCL A;  1XXP A;  1PH0 A;  2Y68 A;  2VTD A;  2NZ6 A;  3A5J A;  1YWF A;  3EU0 A;  3ZMP A;  2ZN7 A;  5KAD A;  4QDI A;  1OHD A;  3MMJ A;  2Y67 A;  1JLN A;  4ZRT A;  4HRF A;  2CJZ A;  4IKC A;  2CM3 A;  2XJA A;  3NRS A;  3QCD A;  2HNQ A;  1J6U A;  3H2X A;  4WU2 A;  2GCB A;  2Q47 A;  4UAG A;  2F6Y A;  2QDC A;  4TVV A;  2P6X A;  4OHD A;  5KA0 A;  3QCC A;  4QF5 A;  2CNF A;  3QCB A;  3OMH A;  2BGE A;  2I6I A;  2B4O A;  2Q05 A;  2Y96 A;  3BRH A;  1W78 A;  2I3R A;  3PS5 A;  4RH9 A;  1NNY A;  2GWO A;  4ICZ A;  3S3K A;  4S0G A;  1Q6T A;  1PTT A;  2HCM A;  1UAG A;  2RF6 A;  3O3L A;  3QCL A;  2NLK A;  3ZMQ A;  2F6V A;  4NND A;  1J4X A;  1Q6P A;  4QUN A;  2ZMM A;  1ZZW A;  1SUG A;  2I4E A;  2I4G A;  2PA5 A;  3QCN A;  2GC5 A;  3HN7 A;  4PYH A;  4I8N A;  5A5E A;  2B07 A;  1L8G A;  2QCT A;  3O5X A;  1VHR A;  3D1Q A;  3ZM2 A;  2FJN A;  2JJD A;  4KI9 A;  1FPR A;  3AWE A;  3I7Z A;  2VEX A;  4GE2 A;  2OZ5 A;  2R0B A;  5BX1 A;  3O4S A;  4QAH A;  1LAR A;  3O4T A;  2XPC A;  1EEO A;  4NX8 A;  3D42 A;  2F00 A;  3QCF A;  4OHH A;  2PQ5 A;  3QCH A;  3QCZ A;  4H34 A;  1I9T A;  3V0H A;  2F6F A;  1OHE A;  3GXG A;  2Y66 A;  3S3E A;  2WJP A;  4QBE A;  4GRY A;  5IBS A;  4HJQ A;  5KAC A;  4GS0 A;  1PA1 A;  2FJM A;  3MOZ A;  5GTJ A;  4JMK A;  4GE5 A;  1FGS A;  2CMC A;  4B04 A;  4RHG A;  2F70 A;  5KA3 A;  3SR9 A;  1G1H A;  3UAG A;  4DGP A;  1OEM X;  1XRI A;  1R6H A;  4PVG A;  1KAK A;  2B3O A;  3QCG A;  1RPM A;  2I75 A;  3F9A A;  1C84 A;  3N2A A;  3V0E A;  3MVN A;  4RI4 A;  3ZM0 A;  3D1H A;  1GFY A;  2HC2 A;  2I6M A;  2CMA A;  1X24 A;  3F81 A;  4AZ1 A;  2ESB A;  1OEU A;  1JBW A;  4C12 A;  1BZC A;  3BLU A;  4QAP A;  1G7F A;  2I6P A;  4BPC A;  2UUO A;  2I4H A;  3F99 A;  3RO1 A;  1C85 A;  2AHS A;  2I42 A;  1KAV A;  2VOR A;  3M4U A;  2PSZ A;  4KYR A;  2IMG A;  1PTY A;  5MMZ B;  2C7S A;  4GFV A;  4Y14 A;  2HVL A;  3ZM1 A;  3CM3 A;  2F6Z A;  3N0A A;  5LXQ B;  4RH5 A;  2UUP A;  2CMB A;  2QBR A;  4RKK A;  2UAG A;  4R30 A;  2HC1 A;  4NYH A;  5K24 A;  2F71 A;  5KA9 A;  3QKP A;  5HDE A;  4ZIY A;  1A5Y A;  2YDU A;  1OES A;  1ECV A;  1T4J A;  3O4U A;  3EAX A;  3QCI A;  2HB1 A;  2CNE A;  5K9V A;  1PTU A;  1U26 A;  3PYZ A;  2GJT A;  3ZM3 A;  2AM2 A;  4OHL A;  4NWF A;  3U96 A;  1FQ1 A;  3V0J A;  3EMU A;  4JNB A;  5J8R A;  2CM7 A;  3RGQ A;  3QCE A;  1P31 A;  4BJO A;  1AAX A;  2GC6 A;  1PYN A;  2WTZ A;  5KA7 A;  2I1Y A;  3AWF A;  4KYQ A;  4OHE A;  2QBQ A;  1JF7 A;  5K23 A;  1NO6 A;  2B4U A;  1GQQ A;  1OET A;  1V3A A;  2Y2F A;  3EB1 A;  4ERC A;  2NT7 A;  4C13 A;  1XXV A;  4JMJ A;  3ZL8 A;  1NWE A;  4J51 A;  5KAA A;  5KA2 A;  3ZM5 A;  3V0F A;  3V0I A;  3QCK A;  1T48 A;  5A5F A;  3BLT A;  5IBM A;  1PXH A;  2VEU A;  2C46 A;  3A5K A;  1EEN A;  3I36 A;  1YN9 A;  1C88 A;  4QUM A;  2J16 A;  2PBN A;  1EEH A;  1NZ7 A;  2HY3 A;  4Z6B A;  4D3Q A;  1ONY A;  1ONZ A;  1C87 A;  2MBC A;  2QEP A;  2I5X A;  2Y1O A;  1OEO X;  3AWG A;  3NME A;  4NWG A;  2B49 A;  3ZM6 A;  2BIJ A;  4D3R A;  4HV4 A;  4RDD A;  5KA1 A;  1U25 A;  4CVK A;  4WU3 A;  3EZZ A;  1LQF A;  4Y2E A;  3RGO A;  1G7G A;  2OC3 A;  4GRZ A;  2HNP A;  4RI5 A;  3V0G A;  2H4V A;  3D9C A;  2VEY A;  2G6Z A;  1MKP A;  4OHI A;  3D1O A;  2A3K A;  4GFU A;  2CNH A;  2JFH A;  5KA8 A;  1G4W R;  2NT2 A;  2BGD A;  2VEV A;  4ZI4 A;  5K25 A;  2OUD A;  2H02 A;  5AWX A;  2VTE A;  3BM8 A;  2VOS A;  5BZX A;  4QBW A;  4R0S A;  1GWZ A;  1NL9 A;  1YPT A;  5EHP A;  1YTS A;  1PTV A;  3B7O A;  2F46 A;  3QCJ A;  1XBO A;  3S3H A;  1WCH A;  1YGU A;  1OEV A;  2H03 A;  2NTA A;  1PA9 A;  1Q6S A;  1U24 A;  3F9B A;  4YAA A;  2NV5 A;  1WRM A;  4DGX A;  2VEW A;  2GCA A;  2CFV A;  1YGR A;  2I6J A;  2M3V A;  2B4S A;  4WOH A;  2PT0 A;  4D3P A;  1G1G A;  1OHC A;  1ZCK A;  2AM1 A;  1BZJ A;  2CNG A;  1P15 A;  2A8B A;  2QDP A;  4CVL A;  2H04 A;  5K9W A;  3MOW A;  5K22 A;  1QZ0 A;  1C83 A;  3CWE A;  2H4K A;  3D44 A;  2I6O A;  3S3F A;  2P4D A;  1BZH A;  1M3G A;  5EHR A;  4WTY A;  1LYV A;  3LJ8 A;  3V0D A;  2H4G A;  1YTW A;  2PI7 A;  3LK7 A;  2FH7 A;  4CVM A;  1Q6M A;  1WAX A;  3F41 A;  2JFF A;  3QKQ A;  5BUG A;  3GXH A;  1YFO A;  1XM2 A;  2HXP A;  1GG4 A;  2BZL A;  2J17 A;  2CM8 A;  1RXD A;  4HJP A;  1O5Z A;  1P3D A;  4H1O A;  2QBP A;  2WGP A;  5M43 A;  1YTN A;  2AZR A;  2CM2 A;  4GE6 A;  2JFG A; 
#chains in the Genus database with same CATH homology
 5KAB A;  1L8K A;  2B4P A;  4ZN5 A;  3S4E A;  2GP0 A;  1C86 A;  3SME A;  1Q6N A;  1Q1M A;  2DXP A;  2QBS A;  1ZC0 A;  2SHP A;  3RZ2 A;  1Q6J A;  4YR8 B;  1QXK A;  3ZV2 A;  2OOQ A;  1T49 A;  5KA4 A;  2QCJ A;  1YZ4 A;  3OLR A;  1I9S A;  2J16 B;  2G59 A;  3I80 A;  2BV5 A;  2F6W A;  1FPZ A;  1D5R A;  2I3U A;  4JBC A;  5BZZ A;  1G4U S;  2QDM A;  3QCM A;  5I6V A;  1NWL A;  1G1F A;  3S4O A;  4GWF A;  1I57 A;  2F6T A;  4R0T A;  4MBB A;  2CNI A;  2E0T A;  1ZCL A;  1XXP A;  1PH0 A;  2NZ6 A;  3A5J A;  1YWF A;  3EU0 A;  3ZMP A;  2ZN7 A;  5KAD A;  1OHD A;  3MMJ A;  1JLN A;  4ZRT A;  4HRF A;  2CJZ A;  4IKC A;  2CM3 A;  3QCD A;  2HNQ A;  3H2X A;  4WU2 A;  2Q47 A;  2F6Y A;  2QDC A;  4TVV A;  2P6X A;  4OHD A;  5KA0 A;  3QCC A;  2CNF A;  3QCB A;  3OMH A;  2BGE A;  2I6I A;  2B4O A;  2Q05 A;  2Y96 A;  3BRH A;  2I3R A;  3PS5 A;  4RH9 A;  1NNY A;  2GWO A;  4ICZ A;  3S3K A;  4S0G A;  1Q6T A;  1PTT A;  2HCM A;  2RF6 A;  3O3L A;  3QCL A;  2NLK A;  3ZMQ A;  2F6V A;  4NND A;  1J4X A;  1Q6P A;  4QUN A;  2ZMM A;  1ZZW A;  1SUG A;  2I4E A;  2I4G A;  2PA5 A;  3QCN A;  4PYH A;  4I8N A;  2B07 A;  1L8G A;  2QCT A;  3O5X A;  1VHR A;  3D1Q A;  2FJN A;  2JJD A;  4KI9 A;  1FPR A;  3AWE A;  3I7Z A;  2VEX A;  4GE2 A;  2OZ5 A;  2R0B A;  5BX1 A;  3O4S A;  4QAH A;  1LAR A;  3O4T A;  1EEO A;  4NX8 A;  3D42 A;  3QCF A;  4OHH A;  2PQ5 A;  3QCH A;  4H34 A;  3V0H A;  1I9T A;  2F6F A;  1OHE A;  3GXG A;  3S3E A;  4QBE A;  4GRY A;  5IBS A;  4HJQ A;  5KAC A;  4GS0 A;  1PA1 A;  2FJM A;  3MOZ A;  5GTJ A;  4JMK A;  4GE5 A;  2CMC A;  4B04 A;  4RHG A;  2F70 A;  5KA3 A;  3SR9 A;  1G1H A;  4DGP A;  1OEM X;  1XRI A;  1R6H A;  4PVG A;  1KAK A;  2B3O A;  3QCG A;  1RPM A;  2I75 A;  3F9A A;  1C84 A;  3V0E A;  4RI4 A;  3ZM0 A;  3D1H A;  1GFY A;  2HC2 A;  2I6M A;  2CMA A;  1X24 A;  3F81 A;  4AZ1 A;  2ESB A;  1OEU A;  1BZC A;  3BLU A;  4QAP A;  1G7F A;  2I6P A;  4BPC A;  3F99 A;  2I4H A;  3RO1 A;  1C85 A;  2AHS A;  2I42 A;  1KAV A;  3M4U A;  2PSZ A;  4KYR A;  2IMG A;  1PTY A;  5MMZ B;  2C7S A;  4GFV A;  4Y14 A;  2HVL A;  3ZM1 A;  3CM3 A;  2F6Z A;  3N0A A;  5LXQ B;  4RH5 A;  2CMB A;  2QBR A;  4RKK A;  4R30 A;  2HC1 A;  4NYH A;  5K24 A;  2F71 A;  5KA9 A;  3QKP A;  5HDE A;  1A5Y A;  2YDU A;  1OES A;  1ECV A;  1T4J A;  3O4U A;  3EAX A;  3QCI A;  2HB1 A;  2CNE A;  5K9V A;  1PTU A;  1U26 A;  2GJT A;  3ZM3 A;  4OHL A;  4NWF A;  3U96 A;  1FQ1 A;  3V0J A;  3EMU A;  4JNB A;  5J8R A;  2CM7 A;  3RGQ A;  3QCE A;  4BJO A;  1AAX A;  1PYN A;  5KA7 A;  2I1Y A;  3AWF A;  4KYQ A;  4OHE A;  2QBQ A;  1JF7 A;  5K23 A;  1NO6 A;  2B4U A;  1OET A;  1V3A A;  2Y2F A;  3EB1 A;  4ERC A;  2NT7 A;  1XXV A;  4JMJ A;  1NWE A;  4J51 A;  5KAA A;  5KA2 A;  3V0F A;  3V0I A;  3QCK A;  1T48 A;  3BLT A;  5IBM A;  1PXH A;  2VEU A;  2C46 A;  3A5K A;  1EEN A;  3I36 A;  1YN9 A;  1C88 A;  4QUM A;  2J16 A;  2PBN A;  4Z6B A;  1NZ7 A;  2HY3 A;  4D3Q A;  1ONY A;  1ONZ A;  1C87 A;  2MBC A;  2QEP A;  2I5X A;  1OEO X;  3AWG A;  3NME A;  4NWG A;  2B49 A;  5KA1 A;  2BIJ A;  4D3R A;  4RDD A;  1U25 A;  4WU3 A;  3EZZ A;  1LQF A;  4Y2E A;  3RGO A;  1G7G A;  2OC3 A;  4GRZ A;  2HNP A;  4RI5 A;  3V0G A;  2H4V A;  3D9C A;  2VEY A;  2G6Z A;  1MKP A;  4OHI A;  3D1O A;  2A3K A;  4GFU A;  2CNH A;  5KA8 A;  1G4W R;  2NT2 A;  2BGD A;  2VEV A;  4ZI4 A;  5K25 A;  2OUD A;  2H02 A;  5AWX A;  3BM8 A;  5BZX A;  4QBW A;  4R0S A;  1GWZ A;  1NL9 A;  1YPT A;  5EHP A;  1YTS A;  1PTV A;  3B7O A;  2F46 A;  3QCJ A;  1XBO A;  3S3H A;  1WCH A;  1YGU A;  1OEV A;  2H03 A;  2NTA A;  1PA9 A;  1Q6S A;  1U24 A;  3F9B A;  4YAA A;  2NV5 A;  1WRM A;  4DGX A;  2VEW A;  2CFV A;  1YGR A;  2I6J A;  2M3V A;  2B4S A;  4WOH A;  2PT0 A;  4D3P A;  1G1G A;  1OHC A;  1ZCK A;  1BZJ A;  2CNG A;  1P15 A;  2A8B A;  2QDP A;  2H04 A;  5K9W A;  3MOW A;  5K22 A;  1QZ0 A;  1C83 A;  3CWE A;  2H4K A;  3D44 A;  2I6O A;  3S3F A;  2P4D A;  1BZH A;  1M3G A;  5EHR A;  4WTY A;  1LYV A;  3LJ8 A;  3V0D A;  2H4G A;  1YTW A;  2PI7 A;  2FH7 A;  1Q6M A;  1WAX A;  3F41 A;  3QKQ A;  5BUG A;  3GXH A;  1YFO A;  1XM2 A;  2HXP A;  2BZL A;  2J17 A;  2CM8 A;  1RXD A;  4HJP A;  4H1O A;  2QBP A;  2WGP A;  5M43 A;  1YTN A;  2AZR A;  2CM2 A;  4GE6 A;  3ZM2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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