1ZE1A

Conformational change of pseudouridine 55 synthase upon its association with rna substrate
Total Genus 77
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
308
structure length
308
Chain Sequence
MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKHERQRRVLTLRKVFQT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords tRNA pseudouridine synthase B
publication title Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
pubmed doi rcsb
source organism Thermotoga maritima
molecule tags Lyase
total genus 77
structure length 308
sequence length 308
chains with identical sequence B, C, D
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1ze1A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1ze1A01
1R3EA 3U28A 1WXXA 2AB4A 1KSKA 2CX0A 1PRZA 3LWQA 1J2BA 3HJWA 1KSVA 1IQ8A 3C0KA 2J5TA 1KSLA 1SGVA 2I82A 4LABA 4DMGA 3LWPA 2CWWA 3HAXA 1IT8A 2J5VA 2APOA 3LWVA 3HJYA 2CX1A 2AUSA 1XPIA 1SQWA 1R3FA 4LGTA 1Q7HA 3D79A 1K8WA 2ISTA 1ZE2A 2HVYA 2RFKA 1ZS7A 1IT7A 1T5YA 2Q07A 3LDFA 2AS0A 4Q1TA 3VSEA 3MQKA 1ZE1A 1V9KA 3LWOA 2EY4A 3UAIA 1V9FA 1ZL3A 3DH3A 2B78A 1QYUA 1WXWA 2P38A 3LWRA
chains in the Genus database with same CATH superfamily
2KKUA 2AB4A 1KSKA 2CX0A 1J2BA 1KSVA 1IQ8A 2I82A 1IT8A 2J5VA 3HJYA 1XPIA 3ZV0C 2RFKA 1K8WA 2ISTA 1ZE2A 1Z2ZA 3VSEA 2Q07A 3LDFA 2AS0A 1SB7A 1ZE1A 1V9KA 1S04A 2EY4A 3IUWA 1QYUA 4CI3B 3LWOA 2J5TA 4LABA 4CI1B 4DMGA 2FRXA 3LWVA 2APOA 2CX1A 3M6WA 2ANEA 3M4XA 1SQWA 4LGTA 1Q7HA 2HVYA 1IT7A 4Q1TA 3MQKA 3M6UA 1ZL3A 3M6XA 1R3EA 3LWQA 3HJWA 1WK2A 1KSLA 3LWPA 2CWWA 3HAXA 2AUSA 3M6VA 1UOYA 1SI7A 3DH3A 2Z0TA 3U28A 1WXXA 1PRZA 3M65A 3C0KA 1SGVA 4TZ4C 1TE7A 1ZBOA 2E5OA 3LJCA 1R3FA 3D79A 1ZS7A 1T5YA 2DP9A 4CI2B 3UAIA 1V9FA 1SZWA 2B78A 1XNEA 1WXWA 2P38A 3LWRA
chains in the Genus database with same CATH topology
1R3EA 3U28A 1WXXA 2AB4A 1KSKA 2CX0A 1PRZA 3LWQA 1J2BA 3HJWA 1KSVA 1IQ8A 3C0KA 2J5TA 1KSLA 1SGVA 2I82A 4LABA 4DMGA 3LWPA 2RFKA 2CWWA 3HAXA 1IT8A 2J5VA 2APOA 3LWVA 3HJYA 2CX1A 2AUSA 1XPIA 1SQWA 1R3FA 4LGTA 1Q7HA 3D79A 1K8WA 2ISTA 1ZE2A 1Z2ZA 2HVYA 1ZS7A 1IT7A 1T5YA 2Q07A 3LDFA 2AS0A 4Q1TA 3VSEA 3MQKA 1SB7A 1ZE1A 1V9KA 1SI7A 3LWOA 2EY4A 3UAIA 1V9FA 1ZL3A 1SZWA 2B78A 3DH3A 1QYUA 1WXWA 2P38A 3LWRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R3E A;  3U28 A;  1WXX A;  2AB4 A;  1KSK A;  2CX0 A;  1PRZ A;  3LWQ A;  1J2B A;  3HJW A;  1KSV A;  1IQ8 A;  3C0K A;  2J5T A;  1KSL A;  1SGV A;  2I82 A;  4LAB A;  4DMG A;  3LWP A;  2CWW A;  3HAX A;  1IT8 A;  2J5V A;  2APO A;  3LWV A;  3HJY A;  2CX1 A;  2AUS A;  1XPI A;  1SQW A;  1R3F A;  4LGT A;  1Q7H A;  3D79 A;  1K8W A;  2IST A;  1ZE2 A;  2HVY A;  2RFK A;  1ZS7 A;  1IT7 A;  1T5Y A;  2Q07 A;  3LDF A;  2AS0 A;  4Q1T A;  3VSE A;  3MQK A;  1ZE1 A;  1V9K A;  3LWO A;  2EY4 A;  3UAI A;  1V9F A;  1ZL3 A;  3DH3 A;  2B78 A;  1QYU A;  1WXW A;  2P38 A;  3LWR A; 
#chains in the Genus database with same CATH topology
 2KKU A;  2AB4 A;  1KSK A;  2CX0 A;  1J2B A;  1KSV A;  1IQ8 A;  2I82 A;  1IT8 A;  2J5V A;  3HJY A;  1XPI A;  3ZV0 C;  2RFK A;  1K8W A;  2IST A;  1ZE2 A;  1Z2Z A;  3VSE A;  2Q07 A;  3LDF A;  2AS0 A;  1SB7 A;  1ZE1 A;  1V9K A;  1S04 A;  2EY4 A;  3IUW A;  1QYU A;  4CI3 B;  3LWO A;  2J5T A;  4LAB A;  4CI1 B;  4DMG A;  2FRX A;  3LWV A;  2APO A;  2CX1 A;  3M6W A;  2ANE A;  3M4X A;  1SQW A;  4LGT A;  1Q7H A;  2HVY A;  1IT7 A;  4Q1T A;  3MQK A;  3M6U A;  1ZL3 A;  3M6X A;  1R3E A;  3LWQ A;  3HJW A;  1WK2 A;  1KSL A;  3LWP A;  2CWW A;  3HAX A;  2AUS A;  3M6V A;  1UOY A;  1SI7 A;  3DH3 A;  2Z0T A;  3U28 A;  1WXX A;  1PRZ A;  3M65 A;  3C0K A;  1SGV A;  4TZ4 C;  1TE7 A;  1ZBO A;  2E5O A;  3LJC A;  1R3F A;  3D79 A;  1ZS7 A;  1T5Y A;  2DP9 A;  4CI2 B;  3UAI A;  1V9F A;  1SZW A;  2B78 A;  1XNE A;  1WXW A;  2P38 A;  3LWR A; 
#chains in the Genus database with same CATH homology
 1R3E A;  3U28 A;  1WXX A;  2AB4 A;  1KSK A;  2CX0 A;  1PRZ A;  3LWQ A;  1J2B A;  3HJW A;  1KSV A;  1IQ8 A;  3C0K A;  2J5T A;  1KSL A;  1SGV A;  2I82 A;  4LAB A;  4DMG A;  3LWP A;  2RFK A;  2CWW A;  3HAX A;  1IT8 A;  2J5V A;  2APO A;  3LWV A;  3HJY A;  2CX1 A;  2AUS A;  1XPI A;  1SQW A;  1R3F A;  4LGT A;  1Q7H A;  3D79 A;  1K8W A;  2IST A;  1ZE2 A;  1Z2Z A;  2HVY A;  1ZS7 A;  1IT7 A;  1T5Y A;  2Q07 A;  3LDF A;  2AS0 A;  4Q1T A;  3VSE A;  3MQK A;  1SB7 A;  1ZE1 A;  1V9K A;  1SI7 A;  3LWO A;  2EY4 A;  3UAI A;  1V9F A;  1ZL3 A;  1SZW A;  2B78 A;  3DH3 A;  1QYU A;  1WXW A;  2P38 A;  3LWR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...