1ZE1A

Conformational change of pseudouridine 55 synthase upon its association with rna substrate
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
308
structure length
308
Chain Sequence
MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKHERQRRVLTLRKVFQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
pubmed doi rcsb
molecule keywords tRNA pseudouridine synthase B
molecule tags Lyase
source organism Thermotoga maritima
total genus 77
structure length 308
sequence length 308
chains with identical sequence B, C, D
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1ze1A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1ze1A01
2CWWA 1ZE1A 1ZL3A 1IT7A 2J5VA 1XPIA 2B78A 3MQKA 4DMGA 3C0KA 2Q07A 3LWOA 1R3FA 3HJYA 1PRZA 2CX0A 2J5TA 4LABA 3HJWA 3VSEA 1IT8A 2P38A 2APOA 3HAXA 1Q7HA 1V9FA 1KSVA 3U28A 3UAIA 2CX1A 1SGVA 1ZE2A 3DH3A 1KSLA 1WXWA 1WXXA 2HVYA 1KSKA 1QYUA 1R3EA 4LGTA 2EY4A 2AUSA 1SQWA 1J2BA 2I82A 3D79A 4Q1TA 2AS0A 3LDFA 1V9KA 3LWPA 3LWVA 1ZS7A 1K8WA 2ISTA 3LWRA 2RFKA 1T5YA 3LWQA 1IQ8A 2AB4A
chains in the Genus database with same CATH superfamily
2CWWA 1IT7A 2B78A 3C0KA 1R3FA 3HJWA 4TZ4C 3HAXA 1KSVA 1SI7A 1WXWA 1KSKA 3M6UA 1R3EA 2EY4A 3M6VA 1TE7A 3ZV0C 2I82A 3M65A 1S04A 2KKUA 3LWRA 2ANEA 3IUWA 1ZL3A 2J5VA 4DMGA 1PRZA 2J5TA 1IT8A 1Q7HA 3LJCA 3M6WA 3DH3A 1KSLA 1Z2ZA 2AUSA 1J2BA 4Q1TA 2AS0A 1V9KA 1K8WA 3LWQA 2AB4A 2E5OA 3MQKA 4CI2B 1XPIA 3LWOA 4LABA 1SZWA 3U28A 1V9FA 2CX1A 1SGVA 3M6XA 1WXXA 2HVYA 1XNEA 3LWVA 1ZBOA 2DP9A 2RFKA 1T5YA 1IQ8A 1ZE1A 3M4XA 2Q07A 3HJYA 2CX0A 2Z0TA 3VSEA 2APOA 2P38A 1WK2A 1SB7A 3UAIA 1ZE2A 1UOYA 4CI3B 1QYUA 4LGTA 1SQWA 3LWPA 3LDFA 1ZS7A 4CI1B 2ISTA 3D79A 2FRXA
chains in the Genus database with same CATH topology
2CWWA 1ZE1A 1ZL3A 1IT7A 2J5VA 1XPIA 2B78A 3MQKA 4DMGA 3C0KA 2Q07A 3LWOA 1R3FA 3HJYA 1PRZA 2CX0A 2J5TA 4LABA 3HJWA 3VSEA 1IT8A 2P38A 2APOA 3HAXA 1SZWA 1Q7HA 1SB7A 1KSVA 1V9FA 3UAIA 2CX1A 1SGVA 1ZE2A 3U28A 1SI7A 3DH3A 1KSLA 1WXWA 1WXXA 1Z2ZA 2HVYA 1KSKA 1QYUA 1R3EA 4LGTA 2EY4A 2AUSA 1SQWA 1J2BA 2I82A 3D79A 4Q1TA 2AS0A 3LDFA 1V9KA 3LWPA 3LWVA 1ZS7A 1K8WA 2ISTA 3LWRA 2RFKA 1T5YA 3LWQA 1IQ8A 2AB4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CWW A;  1ZE1 A;  1ZL3 A;  1IT7 A;  2J5V A;  1XPI A;  2B78 A;  3MQK A;  4DMG A;  3C0K A;  2Q07 A;  3LWO A;  1R3F A;  3HJY A;  1PRZ A;  2CX0 A;  2J5T A;  4LAB A;  3HJW A;  3VSE A;  1IT8 A;  2P38 A;  2APO A;  3HAX A;  1Q7H A;  1V9F A;  1KSV A;  3U28 A;  3UAI A;  2CX1 A;  1SGV A;  1ZE2 A;  3DH3 A;  1KSL A;  1WXW A;  1WXX A;  2HVY A;  1KSK A;  1QYU A;  1R3E A;  4LGT A;  2EY4 A;  2AUS A;  1SQW A;  1J2B A;  2I82 A;  3D79 A;  4Q1T A;  2AS0 A;  3LDF A;  1V9K A;  3LWP A;  3LWV A;  1ZS7 A;  1K8W A;  2IST A;  3LWR A;  2RFK A;  1T5Y A;  3LWQ A;  1IQ8 A;  2AB4 A; 
#chains in the Genus database with same CATH topology
 2CWW A;  1IT7 A;  2B78 A;  3C0K A;  1R3F A;  3HJW A;  4TZ4 C;  3HAX A;  1KSV A;  1SI7 A;  1WXW A;  1KSK A;  3M6U A;  1R3E A;  2EY4 A;  3M6V A;  1TE7 A;  3ZV0 C;  2I82 A;  3M65 A;  1S04 A;  2KKU A;  3LWR A;  2ANE A;  3IUW A;  1ZL3 A;  2J5V A;  4DMG A;  1PRZ A;  2J5T A;  1IT8 A;  1Q7H A;  3LJC A;  3M6W A;  3DH3 A;  1KSL A;  1Z2Z A;  2AUS A;  1J2B A;  4Q1T A;  2AS0 A;  1V9K A;  1K8W A;  3LWQ A;  2AB4 A;  2E5O A;  3MQK A;  4CI2 B;  1XPI A;  3LWO A;  4LAB A;  1SZW A;  3U28 A;  1V9F A;  2CX1 A;  1SGV A;  3M6X A;  1WXX A;  2HVY A;  1XNE A;  3LWV A;  1ZBO A;  2DP9 A;  2RFK A;  1T5Y A;  1IQ8 A;  1ZE1 A;  3M4X A;  2Q07 A;  3HJY A;  2CX0 A;  2Z0T A;  3VSE A;  2APO A;  2P38 A;  1WK2 A;  1SB7 A;  3UAI A;  1ZE2 A;  1UOY A;  4CI3 B;  1QYU A;  4LGT A;  1SQW A;  3LWP A;  3LDF A;  1ZS7 A;  4CI1 B;  2IST A;  3D79 A;  2FRX A; 
#chains in the Genus database with same CATH homology
 2CWW A;  1ZE1 A;  1ZL3 A;  1IT7 A;  2J5V A;  1XPI A;  2B78 A;  3MQK A;  4DMG A;  3C0K A;  2Q07 A;  3LWO A;  1R3F A;  3HJY A;  1PRZ A;  2CX0 A;  2J5T A;  4LAB A;  3HJW A;  3VSE A;  1IT8 A;  2P38 A;  2APO A;  3HAX A;  1SZW A;  1Q7H A;  1SB7 A;  1KSV A;  1V9F A;  3UAI A;  2CX1 A;  1SGV A;  1ZE2 A;  3U28 A;  1SI7 A;  3DH3 A;  1KSL A;  1WXW A;  1WXX A;  1Z2Z A;  2HVY A;  1KSK A;  1QYU A;  1R3E A;  4LGT A;  2EY4 A;  2AUS A;  1SQW A;  1J2B A;  2I82 A;  3D79 A;  4Q1T A;  2AS0 A;  3LDF A;  1V9K A;  3LWP A;  3LWV A;  1ZS7 A;  1K8W A;  2IST A;  3LWR A;  2RFK A;  1T5Y A;  3LWQ A;  1IQ8 A;  2AB4 A; 
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