1ZEBA

X-ray structure of alkaline phosphatase from human placenta in complex with 5'-amp
Total Genus 173
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
Knots found
sequence length
480
structure length
479
Chain Sequence
IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
pubmed doi rcsb
molecule tags Hydrolase
total genus 173
structure length 479
sequence length 480
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2005-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1zebA00
4LR8A 4CYSA 1ALHA 2IFYA 3UO0A 1EJJA 3IGZB 3MK0A 5TJ3A 1EW8A 3NKPA 1SHNA 4MY4A 4LREA 1ALIA 1KHLA 2W5VA 3WAYA 5DLTA 1AJDA 1B8JA 3T02A 1KHJA 1ELYA 3B5QA 3WBHA 5L0BA 2W5TA 3UN3A 1ELZA 4LR9A 2X98A 2XRGA 3MK1A 4KAYA 4LR7A 5IJSA 5DLVA 2IUCB 4MHXA 3SZYA 2RH6A 1KHKA 1P49A 3E2DA 3NKRA 5LRMA 3NKQA 2W8DA 3CMRA 3UN2A 4CXKA 4FDJA 3T01A 1HQAA 4MIVA 4UOOA 5KXAA 4KJGA 5AJ9A 1EI6A 2GSUA 4KJDA 3UN5A 3T00A 5GOVA 3NKMA 3WAVA 4GTZA 2GA3A 1SHQA 4CXUA 1O99A 4LRDA 1AJAA 1O98A 2ZKTA 1FSUA 3ED4A 4ZG6A 3BDHA 3DPCA 4UPIA 5INHA 1E3CP 1AJCA 1AUKA 4GTWA 3SZZA 4UPHA 3WAXA 2IUCA 2QZUA 1Y6VA 1K7HA 1EW2A 4UPKA 4LQYA 2W5RA 1KH7A 4FDIA 3OT9A 3TWZA 2XR9A 1KH9A 5LQQA 3M7VA 4NWJA 3IGYB 3BDGA 2VQRA 4UOPA 4CXSA 1N2LA 3TX0A 3TG0A 1ED9A 1KH5A 4LRBA 5EGEA 3IDDA 3BDGB 2D1GA 1N2KA 3NKOA 1ZEDA 4GTXA 4LRFA 2G9YA 4NWXA 4QAXA 5C66A 5HRTA 1ZEBA 3LXQA 5L0EA 3NVLA 2GSOA 1EQJA 3M8YA 4ZG9A 4GTYA 3KD8A 3A52A 3M8ZA 4CYRA 1ED8A 3NKNA 3Q3QA 1EW9A 4N7TA 5L0KA 3MK2A 2W5WA 2W5QA 4TN0A 1URAA 1E1ZP 3UNYA 4YR1A 4ZG7A 1E2SP 5IJQA 1AJBA 2GLQA 5GRRA 2W5SA 3WAWA 1ELXA 4KM4A 4LR2A 4LRCA 1KHNA 2GSNA 4UORA 4UPLA 5DLWA 4LRAA 1ZEFA 4ZGAA 5LIAA 3BDFA 1ANIA 1ALJA 5EGHA 5K4PA 1HJKA 1ALKA 3M8WA 1Y7AA 1E33P 1HDHA 1ANJA 3DYCA 1URBA 1KH4A 2W5XA 2ANHA 4B56A 5LRNA 4KAVA 2W8SA
chains in the Genus database with same CATH superfamily
4LR8A 4CYSA 1ALHA 2IFYA 3UO0A 1EJJA 3IGZB 3MK0A 5TJ3A 1EW8A 3NKPA 1SHNA 4MY4A 4LREA 1ALIA 1KHLA 2W5VA 3WAYA 5DLTA 1AJDA 1B8JA 3T02A 1KHJA 1ELYA 3B5QA 3WBHA 5L0BA 2W5TA 3UN3A 1ELZA 4LR9A 2X98A 2XRGA 3MK1A 4KAYA 4LR7A 5IJSA 5DLVA 2IUCB 4MHXA 3SZYA 2RH6A 1KHKA 1P49A 3E2DA 3NKRA 5LRMA 3NKQA 2W8DA 3CMRA 3UN2A 4CXKA 4FDJA 3T01A 1HQAA 4MIVA 4UOOA 5KXAA 4KJGA 5AJ9A 1EI6A 2GSUA 4KJDA 3UN5A 3T00A 5GOVA 3NKMA 3WAVA 4GTZA 2GA3A 1SHQA 4CXUA 1O99A 4LRDA 1AJAA 1O98A 2ZKTA 1FSUA 3ED4A 4ZG6A 3BDHA 3DPCA 4UPIA 5INHA 1E3CP 1AJCA 1AUKA 4GTWA 3SZZA 4UPHA 3WAXA 2IUCA 2QZUA 1Y6VA 1K7HA 1EW2A 4UPKA 4LQYA 2W5RA 1KH7A 4FDIA 3OT9A 3TWZA 2XR9A 1KH9A 5LQQA 3M7VA 4NWJA 3IGYB 3BDGA 2VQRA 4UOPA 4CXSA 1N2LA 3TX0A 3TG0A 1ED9A 1KH5A 4LRBA 5EGEA 3IDDA 3BDGB 2D1GA 1N2KA 3NKOA 1ZEDA 4GTXA 4LRFA 2G9YA 4NWXA 4QAXA 5C66A 5HRTA 1ZEBA 3LXQA 5L0EA 3NVLA 2GSOA 1EQJA 3M8YA 4ZG9A 4GTYA 3KD8A 3A52A 3M8ZA 4CYRA 1ED8A 3NKNA 3Q3QA 1EW9A 4N7TA 5L0KA 3MK2A 2W5WA 2W5QA 4TN0A 1URAA 1E1ZP 3UNYA 4YR1A 4ZG7A 1E2SP 5IJQA 1AJBA 2GLQA 5GRRA 2W5SA 3WAWA 1ELXA 4KM4A 4LR2A 4LRCA 1KHNA 2GSNA 4UORA 4UPLA 5DLWA 4LRAA 1ZEFA 4ZGAA 5LIAA 3BDFA 1ANIA 1ALJA 5EGHA 5K4PA 1HJKA 1ALKA 3M8WA 1Y7AA 1E33P 1HDHA 1ANJA 3DYCA 1URBA 1KH4A 2W5XA 2ANHA 4B56A 5LRNA 4KAVA 2W8SA
chains in the Genus database with same CATH topology
4LR8A 4CYSA 1ALHA 2IFYA 3UO0A 1EJJA 3IGZB 3MK0A 5TJ3A 1EW8A 3NKPA 1SHNA 4MY4A 4LREA 1ALIA 1KHLA 2W5VA 3WAYA 5DLTA 1AJDA 1B8JA 3T02A 1KHJA 1ELYA 3B5QA 3WBHA 5L0BA 2W5TA 3UN3A 1ELZA 4LR9A 2X98A 2XRGA 3MK1A 4KAYA 4LR7A 5IJSA 5DLVA 2IUCB 4MHXA 3SZYA 2RH6A 1KHKA 1P49A 3E2DA 3NKRA 5LRMA 3NKQA 2W8DA 3CMRA 3UN2A 4CXKA 4FDJA 3T01A 1HQAA 4MIVA 4UOOA 5KXAA 4KJGA 5AJ9A 1EI6A 2GSUA 4KJDA 3UN5A 3T00A 5GOVA 3NKMA 3WAVA 4GTZA 2GA3A 1SHQA 4CXUA 1O99A 4LRDA 1AJAA 1O98A 2ZKTA 1FSUA 3ED4A 4ZG6A 3BDHA 3DPCA 4UPIA 5INHA 1E3CP 1AJCA 1AUKA 4GTWA 3SZZA 4UPHA 3WAXA 2IUCA 2QZUA 1Y6VA 1K7HA 1EW2A 4UPKA 4LQYA 2W5RA 1KH7A 4FDIA 3OT9A 3TWZA 2XR9A 1KH9A 5LQQA 3M7VA 4NWJA 3IGYB 3BDGA 2VQRA 4UOPA 4CXSA 1N2LA 3TX0A 3TG0A 1ED9A 1KH5A 4LRBA 5EGEA 3IDDA 3BDGB 2D1GA 1N2KA 3NKOA 1ZEDA 4GTXA 4LRFA 2G9YA 4NWXA 4QAXA 5C66A 5HRTA 1ZEBA 3LXQA 5L0EA 3NVLA 2GSOA 1EQJA 3M8YA 4ZG9A 4GTYA 3KD8A 3A52A 3M8ZA 4CYRA 1ED8A 3NKNA 3Q3QA 1EW9A 4N7TA 5L0KA 3MK2A 2W5WA 2W5QA 4TN0A 1URAA 1E1ZP 3UNYA 4YR1A 4ZG7A 1E2SP 5IJQA 1AJBA 2GLQA 5GRRA 2W5SA 3WAWA 1ELXA 4KM4A 4LR2A 4LRCA 1KHNA 2GSNA 4UORA 4UPLA 5DLWA 4LRAA 1ZEFA 4ZGAA 5LIAA 3BDFA 1ANIA 1ALJA 5EGHA 5K4PA 1HJKA 1ALKA 3M8WA 1Y7AA 1E33P 1HDHA 1ANJA 3DYCA 1URBA 1KH4A 2W5XA 2ANHA 4B56A 5LRNA 4KAVA 2W8SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LR8 A;  4CYS A;  1ALH A;  2IFY A;  3UO0 A;  1EJJ A;  3IGZ B;  3MK0 A;  5TJ3 A;  1EW8 A;  3NKP A;  1SHN A;  4MY4 A;  4LRE A;  1ALI A;  1KHL A;  2W5V A;  3WAY A;  5DLT A;  1AJD A;  1B8J A;  3T02 A;  1KHJ A;  1ELY A;  3B5Q A;  3WBH A;  5L0B A;  2W5T A;  3UN3 A;  1ELZ A;  4LR9 A;  2X98 A;  2XRG A;  3MK1 A;  4KAY A;  4LR7 A;  5IJS A;  5DLV A;  2IUC B;  4MHX A;  3SZY A;  2RH6 A;  1KHK A;  1P49 A;  3E2D A;  3NKR A;  5LRM A;  3NKQ A;  2W8D A;  3CMR A;  3UN2 A;  4CXK A;  4FDJ A;  3T01 A;  1HQA A;  4MIV A;  4UOO A;  5KXA A;  4KJG A;  5AJ9 A;  1EI6 A;  2GSU A;  4KJD A;  3UN5 A;  3T00 A;  5GOV A;  3NKM A;  3WAV A;  4GTZ A;  2GA3 A;  1SHQ A;  4CXU A;  1O99 A;  4LRD A;  1AJA A;  1O98 A;  2ZKT A;  1FSU A;  3ED4 A;  4ZG6 A;  3BDH A;  3DPC A;  4UPI A;  5INH A;  1E3C P;  1AJC A;  1AUK A;  4GTW A;  3SZZ A;  4UPH A;  3WAX A;  2IUC A;  2QZU A;  1Y6V A;  1K7H A;  1EW2 A;  4UPK A;  4LQY A;  2W5R A;  1KH7 A;  4FDI A;  3OT9 A;  3TWZ A;  2XR9 A;  1KH9 A;  5LQQ A;  3M7V A;  4NWJ A;  3IGY B;  3BDG A;  2VQR A;  4UOP A;  4CXS A;  1N2L A;  3TX0 A;  3TG0 A;  1ED9 A;  1KH5 A;  4LRB A;  5EGE A;  3IDD A;  3BDG B;  2D1G A;  1N2K A;  3NKO A;  1ZED A;  4GTX A;  4LRF A;  2G9Y A;  4NWX A;  4QAX A;  5C66 A;  5HRT A;  1ZEB A;  3LXQ A;  5L0E A;  3NVL A;  2GSO A;  1EQJ A;  3M8Y A;  4ZG9 A;  4GTY A;  3KD8 A;  3A52 A;  3M8Z A;  4CYR A;  1ED8 A;  3NKN A;  3Q3Q A;  1EW9 A;  4N7T A;  5L0K A;  3MK2 A;  2W5W A;  2W5Q A;  4TN0 A;  1URA A;  1E1Z P;  3UNY A;  4YR1 A;  4ZG7 A;  1E2S P;  5IJQ A;  1AJB A;  2GLQ A;  5GRR A;  2W5S A;  3WAW A;  1ELX A;  4KM4 A;  4LR2 A;  4LRC A;  1KHN A;  2GSN A;  4UOR A;  4UPL A;  5DLW A;  4LRA A;  1ZEF A;  4ZGA A;  5LIA A;  3BDF A;  1ANI A;  1ALJ A;  5EGH A;  5K4P A;  1HJK A;  1ALK A;  3M8W A;  1Y7A A;  1E33 P;  1HDH A;  1ANJ A;  3DYC A;  1URB A;  1KH4 A;  2W5X A;  2ANH A;  4B56 A;  5LRN A;  4KAV A;  2W8S A; 
#chains in the Genus database with same CATH topology
 4LR8 A;  4CYS A;  1ALH A;  2IFY A;  3UO0 A;  1EJJ A;  3IGZ B;  3MK0 A;  5TJ3 A;  1EW8 A;  3NKP A;  1SHN A;  4MY4 A;  4LRE A;  1ALI A;  1KHL A;  2W5V A;  3WAY A;  5DLT A;  1AJD A;  1B8J A;  3T02 A;  1KHJ A;  1ELY A;  3B5Q A;  3WBH A;  5L0B A;  2W5T A;  3UN3 A;  1ELZ A;  4LR9 A;  2X98 A;  2XRG A;  3MK1 A;  4KAY A;  4LR7 A;  5IJS A;  5DLV A;  2IUC B;  4MHX A;  3SZY A;  2RH6 A;  1KHK A;  1P49 A;  3E2D A;  3NKR A;  5LRM A;  3NKQ A;  2W8D A;  3CMR A;  3UN2 A;  4CXK A;  4FDJ A;  3T01 A;  1HQA A;  4MIV A;  4UOO A;  5KXA A;  4KJG A;  5AJ9 A;  1EI6 A;  2GSU A;  4KJD A;  3UN5 A;  3T00 A;  5GOV A;  3NKM A;  3WAV A;  4GTZ A;  2GA3 A;  1SHQ A;  4CXU A;  1O99 A;  4LRD A;  1AJA A;  1O98 A;  2ZKT A;  1FSU A;  3ED4 A;  4ZG6 A;  3BDH A;  3DPC A;  4UPI A;  5INH A;  1E3C P;  1AJC A;  1AUK A;  4GTW A;  3SZZ A;  4UPH A;  3WAX A;  2IUC A;  2QZU A;  1Y6V A;  1K7H A;  1EW2 A;  4UPK A;  4LQY A;  2W5R A;  1KH7 A;  4FDI A;  3OT9 A;  3TWZ A;  2XR9 A;  1KH9 A;  5LQQ A;  3M7V A;  4NWJ A;  3IGY B;  3BDG A;  2VQR A;  4UOP A;  4CXS A;  1N2L A;  3TX0 A;  3TG0 A;  1ED9 A;  1KH5 A;  4LRB A;  5EGE A;  3IDD A;  3BDG B;  2D1G A;  1N2K A;  3NKO A;  1ZED A;  4GTX A;  4LRF A;  2G9Y A;  4NWX A;  4QAX A;  5C66 A;  5HRT A;  1ZEB A;  3LXQ A;  5L0E A;  3NVL A;  2GSO A;  1EQJ A;  3M8Y A;  4ZG9 A;  4GTY A;  3KD8 A;  3A52 A;  3M8Z A;  4CYR A;  1ED8 A;  3NKN A;  3Q3Q A;  1EW9 A;  4N7T A;  5L0K A;  3MK2 A;  2W5W A;  2W5Q A;  4TN0 A;  1URA A;  1E1Z P;  3UNY A;  4YR1 A;  4ZG7 A;  1E2S P;  5IJQ A;  1AJB A;  2GLQ A;  5GRR A;  2W5S A;  3WAW A;  1ELX A;  4KM4 A;  4LR2 A;  4LRC A;  1KHN A;  2GSN A;  4UOR A;  4UPL A;  5DLW A;  4LRA A;  1ZEF A;  4ZGA A;  5LIA A;  3BDF A;  1ANI A;  1ALJ A;  5EGH A;  5K4P A;  1HJK A;  1ALK A;  3M8W A;  1Y7A A;  1E33 P;  1HDH A;  1ANJ A;  3DYC A;  1URB A;  1KH4 A;  2W5X A;  2ANH A;  4B56 A;  5LRN A;  4KAV A;  2W8S A; 
#chains in the Genus database with same CATH homology
 4LR8 A;  4CYS A;  1ALH A;  2IFY A;  3UO0 A;  1EJJ A;  3IGZ B;  3MK0 A;  5TJ3 A;  1EW8 A;  3NKP A;  1SHN A;  4MY4 A;  4LRE A;  1ALI A;  1KHL A;  2W5V A;  3WAY A;  5DLT A;  1AJD A;  1B8J A;  3T02 A;  1KHJ A;  1ELY A;  3B5Q A;  3WBH A;  5L0B A;  2W5T A;  3UN3 A;  1ELZ A;  4LR9 A;  2X98 A;  2XRG A;  3MK1 A;  4KAY A;  4LR7 A;  5IJS A;  5DLV A;  2IUC B;  4MHX A;  3SZY A;  2RH6 A;  1KHK A;  1P49 A;  3E2D A;  3NKR A;  5LRM A;  3NKQ A;  2W8D A;  3CMR A;  3UN2 A;  4CXK A;  4FDJ A;  3T01 A;  1HQA A;  4MIV A;  4UOO A;  5KXA A;  4KJG A;  5AJ9 A;  1EI6 A;  2GSU A;  4KJD A;  3UN5 A;  3T00 A;  5GOV A;  3NKM A;  3WAV A;  4GTZ A;  2GA3 A;  1SHQ A;  4CXU A;  1O99 A;  4LRD A;  1AJA A;  1O98 A;  2ZKT A;  1FSU A;  3ED4 A;  4ZG6 A;  3BDH A;  3DPC A;  4UPI A;  5INH A;  1E3C P;  1AJC A;  1AUK A;  4GTW A;  3SZZ A;  4UPH A;  3WAX A;  2IUC A;  2QZU A;  1Y6V A;  1K7H A;  1EW2 A;  4UPK A;  4LQY A;  2W5R A;  1KH7 A;  4FDI A;  3OT9 A;  3TWZ A;  2XR9 A;  1KH9 A;  5LQQ A;  3M7V A;  4NWJ A;  3IGY B;  3BDG A;  2VQR A;  4UOP A;  4CXS A;  1N2L A;  3TX0 A;  3TG0 A;  1ED9 A;  1KH5 A;  4LRB A;  5EGE A;  3IDD A;  3BDG B;  2D1G A;  1N2K A;  3NKO A;  1ZED A;  4GTX A;  4LRF A;  2G9Y A;  4NWX A;  4QAX A;  5C66 A;  5HRT A;  1ZEB A;  3LXQ A;  5L0E A;  3NVL A;  2GSO A;  1EQJ A;  3M8Y A;  4ZG9 A;  4GTY A;  3KD8 A;  3A52 A;  3M8Z A;  4CYR A;  1ED8 A;  3NKN A;  3Q3Q A;  1EW9 A;  4N7T A;  5L0K A;  3MK2 A;  2W5W A;  2W5Q A;  4TN0 A;  1URA A;  1E1Z P;  3UNY A;  4YR1 A;  4ZG7 A;  1E2S P;  5IJQ A;  1AJB A;  2GLQ A;  5GRR A;  2W5S A;  3WAW A;  1ELX A;  4KM4 A;  4LR2 A;  4LRC A;  1KHN A;  2GSN A;  4UOR A;  4UPL A;  5DLW A;  4LRA A;  1ZEF A;  4ZGA A;  5LIA A;  3BDF A;  1ANI A;  1ALJ A;  5EGH A;  5K4P A;  1HJK A;  1ALK A;  3M8W A;  1Y7A A;  1E33 P;  1HDH A;  1ANJ A;  3DYC A;  1URB A;  1KH4 A;  2W5X A;  2ANH A;  4B56 A;  5LRN A;  4KAV A;  2W8S A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...