1ZEIA

Cross-linked b28 asp insulin
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
53
structure length
53
Chain Sequence
FVNQHLCGSHLVEALYLVCGERGFFYTDKAAKGIVEQCCTSICSLYQLENYCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords INSULIN
publication title Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
pubmed doi rcsb
source organism Sus scrofa
total genus 13
structure length 53
sequence length 53
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1998-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1zeiA00
2LWZA 2DSQC 1SJUA 1IMXA 2KJIA 6INSE 2GF1A 2DSPI 2DSRI 2JZQA 1IGLA 3GF1A 1GZZB 1B9GA 5L3NA 5L3MA 1GZYB 1EFEA 3KR3D 3LRIA 1BQTA 2KQPA 2L29B 1H59A 5L3LA 1TGRA 1GZRB 4XSSB 1H02B 1PMXA 1WQJI 1ZEIA
chains in the Genus database with same CATH superfamily
2LWZA 2DSQC 1SJUA 3F2CA 1IMXA 2KJIA 6INSE 2GF1A 3F2DA 2DSPI 2DSRI 3F2BA 2JZQA 1IGLA 3GF1A 1GZZB 1B9GA 5L3NA 5L3MA 1GZYB 1EFEA 3KR3D 3LRIA 1BQTA 2KQPA 2L29B 1H59A 2L14B 5L3LA 1TGRA 1GZRB 4XSSB 1H02B 1PMXA 1WQJI 1ZEIA
chains in the Genus database with same CATH topology
2LWZA 2DSQC 1SJUA 1IMXA 2KJIA 6INSE 2GF1A 2DSPI 2DSRI 2JZQA 1IGLA 3GF1A 1GZZB 1B9GA 5L3NA 5L3MA 1GZYB 1EFEA 3KR3D 3LRIA 1BQTA 2KQPA 2L29B 1H59A 5L3LA 1TGRA 1GZRB 4XSSB 1H02B 1PMXA 1WQJI 1ZEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LWZ A;  2DSQ C;  1SJU A;  1IMX A;  2KJI A;  6INS E;  2GF1 A;  2DSP I;  2DSR I;  2JZQ A;  1IGL A;  3GF1 A;  1GZZ B;  1B9G A;  5L3N A;  5L3M A;  1GZY B;  1EFE A;  3KR3 D;  3LRI A;  1BQT A;  2KQP A;  2L29 B;  1H59 A;  5L3L A;  1TGR A;  1GZR B;  4XSS B;  1H02 B;  1PMX A;  1WQJ I;  1ZEI A; 
#chains in the Genus database with same CATH topology
 2LWZ A;  2DSQ C;  1SJU A;  3F2C A;  1IMX A;  2KJI A;  6INS E;  2GF1 A;  3F2D A;  2DSP I;  2DSR I;  3F2B A;  2JZQ A;  1IGL A;  3GF1 A;  1GZZ B;  1B9G A;  5L3N A;  5L3M A;  1GZY B;  1EFE A;  3KR3 D;  3LRI A;  1BQT A;  2KQP A;  2L29 B;  1H59 A;  2L14 B;  5L3L A;  1TGR A;  1GZR B;  4XSS B;  1H02 B;  1PMX A;  1WQJ I;  1ZEI A; 
#chains in the Genus database with same CATH homology
 2LWZ A;  2DSQ C;  1SJU A;  1IMX A;  2KJI A;  6INS E;  2GF1 A;  2DSP I;  2DSR I;  2JZQ A;  1IGL A;  3GF1 A;  1GZZ B;  1B9G A;  5L3N A;  5L3M A;  1GZY B;  1EFE A;  3KR3 D;  3LRI A;  1BQT A;  2KQP A;  2L29 B;  1H59 A;  5L3L A;  1TGR A;  1GZR B;  4XSS B;  1H02 B;  1PMX A;  1WQJ I;  1ZEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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