1ZGKA

1.35 angstrom structure of the kelch domain of keap1
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSNGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 61
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2005-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 1zgkA00
4ZY3A 2WOZA 2ZWAA 3II7A 4IFLX 4XMBA 1U6DX 4L7DA 4CH9A 3WN7A 5FNTA 4YY8A 1X2JA 4IFJA 5F72C 3ZGCA 5FZJA 3ADEA 2ZZKA 5FZNA 5CGJA 5FNQA 3VNHA 4IFNX 2ZW9A 3VNGA 4IN4A 4L7BA 4CHBA 4N1BA 2DYHA 1ZGKA 2VPJA 5FNUA 4ASCA 4L7CA 5FNSA 1X2RA 2FLUX 5FNRA 3ZGDA 4ZGCA 2XN4A 3WDZA 4IQKA 2Z32A
chains in the Genus database with same CATH superfamily
4CPLA 1W20A 3U0SA 4FOQA 1BJIA 1RWIA 3K36A 4IFJA 5B2DA 3NSSA 3KYAA 4XJWA 4FPOB 4KS3A 1L7FA 1VCUA 1N1SA 1B9SA 4GN7A 4J9TA 3TI4A 4XOGA 3A9GA 3D11A 1RWLA 3AMSA 1PJXA 1C5KA 3B69A 4B7MA 4CPOA 1B9TA 4GZOA 2VSKA 3LI5A 4FPHA 5F9TA 4L7DA 1USXA 4MWRA 2A75A 4MC7A 2W38A 5D9BA 4YW3A 2BERA 3V64C 2IAUA 4QN7A 4XIOA 2VW2A 1EUUA 3VNHA 4MZEA 4IFNX 3TI5A 4FP3A 3WWAA 1SNTA 3SLIA 1NPEA 4AGTA 3IAXA 2IAQA 1X2RA 2ZB5A 1NNAA 4HZYA 4M4VA 4HHQA 3SOVA 2HT7A 3HRPA 4BBWA 5B2CA 2HTUA 2FPBA 1E8UA 3AMRA 1MS1A 4WEFA 4D4UA 1U6DX 4K1KA 4O5TA 1N7DA 5JYYA 4YY8A 2AGSA 1EUTA 3W09A 5GX2A 3H73A 2F11A 2DG1A 4UF7A 4HW6A 1MR5A 1IVBA 3FVZA 1WCQA 4FPLA 1A4QA 1NNCA 2XCYA 4O5SA 4FPEA 4CPNA 1W0PA 2QWJA 2W8BB 4B7NA 3P5BL 1V04A 3TI6A 3CL2A 1MS8A 1Z4VA 2HTRA 4IYGA 4XJQA 5EO8A 3BEQA 4NCSA 4FVKA 5CGJA 1V0FA 1W0OA 4DGRA 5HX0A 4FPCA 3PJQA 3ALXA 2SLIA 2G8SA 2HU0A 1V0EA 1MS5A 4YW1A 2SIMA 1IUBA 4B7RA 1MZ6A 2AH2A 3HLHA 3WDZA 2QWHA 1V3CA 4M3MA 4MJVA 4X4AA 4XHXA 3SREA 3H71A 2F12A 2C4AA 4XJUA 5F72C 2HU4A 4DG6A 4YW4A 4GN8A 4MWWA 4HZVA 1MS4A 2YDTA 4FOYA 4GNBA 4CPZA 2DYHA 5D9DA 1F8BA 1E8VA 3LI4A 4SLIA 2IASA 1Z4ZA 3Q6PA 1NSDA 4CPYA 4ZY3A 2GVXA 5HUMA 2WOZA 4HZXA 1S0JA 1CVMA 2W5OA 4IFLX 2X9MA 1INVA 5FNTA 3NO0A 3S8VA 2VK7A 2GHSA 3HLIA 2BF6A 3E5ZA 5FNQA 2VSMA 4B7JA 2YA8A 2AEPA 1CQ1A 2IARA 2JKBA 4YZ5A 3K39A 2HTVA 3TI3A 4FJ6A 3Q6TA 3A72A 1SLLA 2H2UA 3G4EA 4C1YB 3D12A 5GX3A 1A4GA 2HTQA 4GJTA 6NN9A 5D9CA 1MS9A 1CRUA 1IVGA 1A14N 2IAXA 1Z4YA 2YA6A 3BYCA 4K1IA 2H2NA 3A71A 1Z4XA 2VVZA 1INXA 1NNBA 4GNCA 4PWZA 4QN6A 2IAWA 3V1SA 2VK6A 5H47A 2HTWA 3CYEA 1QBIA 2VW0A 1NCCN 1C9UA 1S0IA 4X47A 1S1DA 4XJ8A 1X2JA 4R40A 2IATA 3SRGA 4X6KA 4XILA 4ZLRA 4K1JA 1INYA 2QWCA 3Q6KA 2YA4A 4CHBA 1NMBN 1N6DA 2F28A 3TI8A 4L7CA 3K3AA 4GZPA 3TC9A 1N1TA 1MWEA 3H6JA 4MWLA 5FNRA 2GVUA 1NSCA 1IVEA 2F27A 4K1HA 1Q7FA 3II7A 3I1CA 4CH9A 4MWYA 2V91A 1N6EA 4I00A 3ZGCA 2QWGA 3L6VA 4UOUA 1H6LA 4D52A 3CKZA 5GX1A 1NMAN 4YW5A 4WA5A 1IVDA 1F8DA 2VWDA 4FQ4A 4M4UA 2F26A 2QWBA 1MZ5A 4H53A 1EUSA 2QWIA 4HZWA 4YW2A 1K32A 4GZQA 4XMIA 3S2KA 1V2IA 4IMBA 2FP8A 2YDPA 5FZJA 2F10A 1INWA 5FZNA 1INGA 1QLGA 2IAPA 4FPKA 4L7BA 1IVFA 2POOA 1ZGKA 5FNUA 4MWVA 1DIMA 2F13A 3TICA 4D8SA 4MWUA 2GVWA 2HQSA 5FWWA 1MS3A 1N1YA 2ISMA 2IVZA 2FPCA 2C4LA 2W8BA 4XJ9A 4GEZA 3CL0A 4YZ4A 5M1ZA 5NN9A 4HZZA 3SALA 4K3YA 3WN7A 2FP9A 3NN9A 3INBA 4AHAA 4QN4A 2B8HA 4WEGA 2IAVA 3GVKA 2ZZKA 4X49A 4MWXA 3B7EA 4KS4A 1OFZA 4FOVA 1Z4WA 2YA7A 2GVVA 4HIZA 4Q1UA 4JMLA 3SOBB 2AEQA 3GVJA 5GX5A 5FNSA 2XZIA 2VAQA 3T1EA 2YA5A 4GB1A 5GTQA 2HT8A 2Z32A 3O4PA 1SUUA 1W1XA 1V3BA 1NN2A 4GNAA 1POOA 2HT5A 3O9JA 4H52A 1V3EA 4QN3A 2F0ZA 5EX7A 1IVCA 2F29A 5EO7A 4XYXA 2DG0A 4GDJA 1F8EA 2F24A 4GN9A 3JU4A 4MX0A 3K38A 1USRA 4CPMA 3VNGA 2BZDA 2SILA 4GZXA 4ASCA 3V65B 2F25A 4KS1A 3H72A 3ZGDA 5GX4A 4FOWA 2XN4A 1L7HA 4WA3A 1IJQA 7NN9A 2BATA 5HUGA 1B9VA 5HUNA 2QWAA 4D52C 4D52B 3ADEA 2QWKA 1W21A 2XZJA 4MWQA 1IUCA 4KS2A 4YZ3A 3LI3A 1VCJA 4QN5A 4YZ1A 2QE8A 3TIBA 4AH4A 2QWEA 1E1AA 4M4NA 4IQKA 4XJAA 4XMBA 4C1YA 3DR2A 3S94A 1NCAN 4B7QA 2CMLA 3K37A 1SO7A 4XJZA 4FPYA 4FZHA 4XE9A 2W20A 1INHA 1N1VA 4FP2A 1XOEA 4QNPA 3SILA 4HHOA 1WP5A 4GZWA 1MS0A 1S18A 2HTYA 1NCDN 1W8NA 1CRZA 4KS5A 4N1BA 4MZAA 4A0PA 4XJRA 2VPJA 3G4HA 4GDIA 1Z50A 4JF7A 1INFA 2ZB6A 3S8ZA 1DILA 2QWFA 3SOQA 1L7GA 5HUKA 3OPZA 2VW1A 1ZI0A 3ALWA 1XOGA 3TIAA 4FPJA 4GZTA 1NSBA 4WA4A 1V0ZA 2W5NA 3WW9A 3UC1A 1EURA 2QWDA 4FPFA 2P4OA 1V3DA 4NC5A 1E8TA 4G3NA 4Q6KA 1F8CA 3DASA 3A9HA 2OJHA 4CSDA 1WCSA 2DSOA 3GVLA 2VK5A 4AGIA 1W8OA 2ZWAA 4XMAA 3FW0A 4NN9A 4XIKA 4MWJA 4YZ2A 1SLIA 1NMCA 2RKCA 3SANA 2XZKA 2ZW9A 3KGGA 4FPGA 4IN4A 3O9KA 1N6FA 4XHBA 2FHRA 4GZSA 1NCBN 2IAOA 4MJUA 2FLUX 4ZGCA 1KITA
chains in the Genus database with same CATH topology
4ZY3A 2WOZA 2ZWAA 3II7A 4IFLX 4XMBA 1U6DX 4L7DA 4CH9A 3WN7A 5FNTA 4YY8A 1X2JA 4IFJA 5F72C 3ZGCA 5FZJA 3ADEA 2ZZKA 5FZNA 5CGJA 5FNQA 3VNHA 4IFNX 2ZW9A 3VNGA 4IN4A 4L7BA 4CHBA 4N1BA 2DYHA 1ZGKA 2VPJA 5FNUA 4ASCA 4L7CA 5FNSA 1X2RA 2FLUX 5FNRA 3ZGDA 4ZGCA 2XN4A 3WDZA 4IQKA 2Z32A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZY3 A;  2WOZ A;  2ZWA A;  3II7 A;  4IFL X;  4XMB A;  1U6D X;  4L7D A;  4CH9 A;  3WN7 A;  5FNT A;  4YY8 A;  1X2J A;  4IFJ A;  5F72 C;  3ZGC A;  5FZJ A;  3ADE A;  2ZZK A;  5FZN A;  5CGJ A;  5FNQ A;  3VNH A;  4IFN X;  2ZW9 A;  3VNG A;  4IN4 A;  4L7B A;  4CHB A;  4N1B A;  2DYH A;  1ZGK A;  2VPJ A;  5FNU A;  4ASC A;  4L7C A;  5FNS A;  1X2R A;  2FLU X;  5FNR A;  3ZGD A;  4ZGC A;  2XN4 A;  3WDZ A;  4IQK A;  2Z32 A; 
#chains in the Genus database with same CATH topology
 4CPL A;  1W20 A;  3U0S A;  4FOQ A;  1BJI A;  1RWI A;  3K36 A;  4IFJ A;  5B2D A;  3NSS A;  3KYA A;  4XJW A;  4FPO B;  4KS3 A;  1L7F A;  1VCU A;  1N1S A;  1B9S A;  4GN7 A;  4J9T A;  3TI4 A;  4XOG A;  3A9G A;  3D11 A;  1RWL A;  3AMS A;  1PJX A;  1C5K A;  3B69 A;  4B7M A;  4CPO A;  1B9T A;  4GZO A;  2VSK A;  3LI5 A;  4FPH A;  5F9T A;  4L7D A;  1USX A;  4MWR A;  2A75 A;  4MC7 A;  2W38 A;  5D9B A;  4YW3 A;  2BER A;  3V64 C;  2IAU A;  4QN7 A;  4XIO A;  2VW2 A;  1EUU A;  3VNH A;  4MZE A;  4IFN X;  3TI5 A;  4FP3 A;  3WWA A;  1SNT A;  3SLI A;  1NPE A;  4AGT A;  3IAX A;  2IAQ A;  1X2R A;  2ZB5 A;  1NNA A;  4HZY A;  4M4V A;  4HHQ A;  3SOV A;  2HT7 A;  3HRP A;  4BBW A;  5B2C A;  2HTU A;  2FPB A;  1E8U A;  3AMR A;  1MS1 A;  4WEF A;  4D4U A;  1U6D X;  4K1K A;  4O5T A;  1N7D A;  5JYY A;  4YY8 A;  2AGS A;  1EUT A;  3W09 A;  5GX2 A;  3H73 A;  2F11 A;  2DG1 A;  4UF7 A;  4HW6 A;  1MR5 A;  1IVB A;  3FVZ A;  1WCQ A;  4FPL A;  1A4Q A;  1NNC A;  2XCY A;  4O5S A;  4FPE A;  4CPN A;  1W0P A;  2QWJ A;  2W8B B;  4B7N A;  3P5B L;  1V04 A;  3TI6 A;  3CL2 A;  1MS8 A;  1Z4V A;  2HTR A;  4IYG A;  4XJQ A;  5EO8 A;  3BEQ A;  4NCS A;  4FVK A;  5CGJ A;  1V0F A;  1W0O A;  4DGR A;  5HX0 A;  4FPC A;  3PJQ A;  3ALX A;  2SLI A;  2G8S A;  2HU0 A;  1V0E A;  1MS5 A;  4YW1 A;  2SIM A;  1IUB A;  4B7R A;  1MZ6 A;  2AH2 A;  3HLH A;  3WDZ A;  2QWH A;  1V3C A;  4M3M A;  4MJV A;  4X4A A;  4XHX A;  3SRE A;  3H71 A;  2F12 A;  2C4A A;  4XJU A;  5F72 C;  2HU4 A;  4DG6 A;  4YW4 A;  4GN8 A;  4MWW A;  4HZV A;  1MS4 A;  2YDT A;  4FOY A;  4GNB A;  4CPZ A;  2DYH A;  5D9D A;  1F8B A;  1E8V A;  3LI4 A;  4SLI A;  2IAS A;  1Z4Z A;  3Q6P A;  1NSD A;  4CPY A;  4ZY3 A;  2GVX A;  5HUM A;  2WOZ A;  4HZX A;  1S0J A;  1CVM A;  2W5O A;  4IFL X;  2X9M A;  1INV A;  5FNT A;  3NO0 A;  3S8V A;  2VK7 A;  2GHS A;  3HLI A;  2BF6 A;  3E5Z A;  5FNQ A;  2VSM A;  4B7J A;  2YA8 A;  2AEP A;  1CQ1 A;  2IAR A;  2JKB A;  4YZ5 A;  3K39 A;  2HTV A;  3TI3 A;  4FJ6 A;  3Q6T A;  3A72 A;  1SLL A;  2H2U A;  3G4E A;  4C1Y B;  3D12 A;  5GX3 A;  1A4G A;  2HTQ A;  4GJT A;  6NN9 A;  5D9C A;  1MS9 A;  1CRU A;  1IVG A;  1A14 N;  2IAX A;  1Z4Y A;  2YA6 A;  3BYC A;  4K1I A;  2H2N A;  3A71 A;  1Z4X A;  2VVZ A;  1INX A;  1NNB A;  4GNC A;  4PWZ A;  4QN6 A;  2IAW A;  3V1S A;  2VK6 A;  5H47 A;  2HTW A;  3CYE A;  1QBI A;  2VW0 A;  1NCC N;  1C9U A;  1S0I A;  4X47 A;  1S1D A;  4XJ8 A;  1X2J A;  4R40 A;  2IAT A;  3SRG A;  4X6K A;  4XIL A;  4ZLR A;  4K1J A;  1INY A;  2QWC A;  3Q6K A;  2YA4 A;  4CHB A;  1NMB N;  1N6D A;  2F28 A;  3TI8 A;  4L7C A;  3K3A A;  4GZP A;  3TC9 A;  1N1T A;  1MWE A;  3H6J A;  4MWL A;  5FNR A;  2GVU A;  1NSC A;  1IVE A;  2F27 A;  4K1H A;  1Q7F A;  3II7 A;  3I1C A;  4CH9 A;  4MWY A;  2V91 A;  1N6E A;  4I00 A;  3ZGC A;  2QWG A;  3L6V A;  4UOU A;  1H6L A;  4D52 A;  3CKZ A;  5GX1 A;  1NMA N;  4YW5 A;  4WA5 A;  1IVD A;  1F8D A;  2VWD A;  4FQ4 A;  4M4U A;  2F26 A;  2QWB A;  1MZ5 A;  4H53 A;  1EUS A;  2QWI A;  4HZW A;  4YW2 A;  1K32 A;  4GZQ A;  4XMI A;  3S2K A;  1V2I A;  4IMB A;  2FP8 A;  2YDP A;  5FZJ A;  2F10 A;  1INW A;  5FZN A;  1ING A;  1QLG A;  2IAP A;  4FPK A;  4L7B A;  1IVF A;  2POO A;  1ZGK A;  5FNU A;  4MWV A;  1DIM A;  2F13 A;  3TIC A;  4D8S A;  4MWU A;  2GVW A;  2HQS A;  5FWW A;  1MS3 A;  1N1Y A;  2ISM A;  2IVZ A;  2FPC A;  2C4L A;  2W8B A;  4XJ9 A;  4GEZ A;  3CL0 A;  4YZ4 A;  5M1Z A;  5NN9 A;  4HZZ A;  3SAL A;  4K3Y A;  3WN7 A;  2FP9 A;  3NN9 A;  3INB A;  4AHA A;  4QN4 A;  2B8H A;  4WEG A;  2IAV A;  3GVK A;  2ZZK A;  4X49 A;  4MWX A;  3B7E A;  4KS4 A;  1OFZ A;  4FOV A;  1Z4W A;  2YA7 A;  2GVV A;  4HIZ A;  4Q1U A;  4JML A;  3SOB B;  2AEQ A;  3GVJ A;  5GX5 A;  5FNS A;  2XZI A;  2VAQ A;  3T1E A;  2YA5 A;  4GB1 A;  5GTQ A;  2HT8 A;  2Z32 A;  3O4P A;  1SUU A;  1W1X A;  1V3B A;  1NN2 A;  4GNA A;  1POO A;  2HT5 A;  3O9J A;  4H52 A;  1V3E A;  4QN3 A;  2F0Z A;  5EX7 A;  1IVC A;  2F29 A;  5EO7 A;  4XYX A;  2DG0 A;  4GDJ A;  1F8E A;  2F24 A;  4GN9 A;  3JU4 A;  4MX0 A;  3K38 A;  1USR A;  4CPM A;  3VNG A;  2BZD A;  2SIL A;  4GZX A;  4ASC A;  3V65 B;  2F25 A;  4KS1 A;  3H72 A;  3ZGD A;  5GX4 A;  4FOW A;  2XN4 A;  1L7H A;  4WA3 A;  1IJQ A;  7NN9 A;  2BAT A;  5HUG A;  1B9V A;  5HUN A;  2QWA A;  4D52 C;  4D52 B;  3ADE A;  2QWK A;  1W21 A;  2XZJ A;  4MWQ A;  1IUC A;  4KS2 A;  4YZ3 A;  3LI3 A;  1VCJ A;  4QN5 A;  4YZ1 A;  2QE8 A;  3TIB A;  4AH4 A;  2QWE A;  1E1A A;  4M4N A;  4IQK A;  4XJA A;  4XMB A;  4C1Y A;  3DR2 A;  3S94 A;  1NCA N;  4B7Q A;  2CML A;  3K37 A;  1SO7 A;  4XJZ A;  4FPY A;  4FZH A;  4XE9 A;  2W20 A;  1INH A;  1N1V A;  4FP2 A;  1XOE A;  4QNP A;  3SIL A;  4HHO A;  1WP5 A;  4GZW A;  1MS0 A;  1S18 A;  2HTY A;  1NCD N;  1W8N A;  1CRZ A;  4KS5 A;  4N1B A;  4MZA A;  4A0P A;  4XJR A;  2VPJ A;  3G4H A;  4GDI A;  1Z50 A;  4JF7 A;  1INF A;  2ZB6 A;  3S8Z A;  1DIL A;  2QWF A;  3SOQ A;  1L7G A;  5HUK A;  3OPZ A;  2VW1 A;  1ZI0 A;  3ALW A;  1XOG A;  3TIA A;  4FPJ A;  4GZT A;  1NSB A;  4WA4 A;  1V0Z A;  2W5N A;  3WW9 A;  3UC1 A;  1EUR A;  2QWD A;  4FPF A;  2P4O A;  1V3D A;  4NC5 A;  1E8T A;  4G3N A;  4Q6K A;  1F8C A;  3DAS A;  3A9H A;  2OJH A;  4CSD A;  1WCS A;  2DSO A;  3GVL A;  2VK5 A;  4AGI A;  1W8O A;  2ZWA A;  4XMA A;  3FW0 A;  4NN9 A;  4XIK A;  4MWJ A;  4YZ2 A;  1SLI A;  1NMC A;  2RKC A;  3SAN A;  2XZK A;  2ZW9 A;  3KGG A;  4FPG A;  4IN4 A;  3O9K A;  1N6F A;  4XHB A;  2FHR A;  4GZS A;  1NCB N;  2IAO A;  4MJU A;  2FLU X;  4ZGC A;  1KIT A; 
#chains in the Genus database with same CATH homology
 4ZY3 A;  2WOZ A;  2ZWA A;  3II7 A;  4IFL X;  4XMB A;  1U6D X;  4L7D A;  4CH9 A;  3WN7 A;  5FNT A;  4YY8 A;  1X2J A;  4IFJ A;  5F72 C;  3ZGC A;  5FZJ A;  3ADE A;  2ZZK A;  5FZN A;  5CGJ A;  5FNQ A;  3VNH A;  4IFN X;  2ZW9 A;  3VNG A;  4IN4 A;  4L7B A;  4CHB A;  4N1B A;  2DYH A;  1ZGK A;  2VPJ A;  5FNU A;  4ASC A;  4L7C A;  5FNS A;  1X2R A;  2FLU X;  5FNR A;  3ZGD A;  4ZGC A;  2XN4 A;  3WDZ A;  4IQK A;  2Z32 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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