1ZJRA

Crystal structure of a. aeolicus trmh/spou trna modifying enzyme
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
197
structure length
197
Chain Sequence
LVLEKRLKRLREVLEKRQKDLIVFADNVKNEHNFSAIVRTCDAVGVLYLYYYHAEGKKAKINEGITQGSHKWVFIEKVDNPVQKLLEFKNRGFQIVATWLSKESVNFREVDYTKPTVLVVGNELQGVSPEIVEIADKKIVIPMYGMAQSLNVSVATGIILYEAQRQREEKGMYSRPSLSEEEIQKILKKWAYEDVIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus.
pubmed doi rcsb
molecule tags Transferase
source organism Aquifex aeolicus
molecule keywords tRNA (Guanosine-2'-O-)-methyltransferase
total genus 69
structure length 197
sequence length 197
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.34: tRNA (guanosine(18)-2'-O)-methyltransferase.
pdb deposition date 2005-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
A PF12105 SpoU_methylas_C SpoU, rRNA methylase, C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1zjrA00
1X7PA 4H3ZA 4YQTA 3ILKA 4CNFA 4YQRA 4FAKA 4YQ1A 4YQGA 3OINA 3IEFA 1IPAA 3N4KA 3AI9X 4YQDA 4PZKA 1TO0A 4YQSA 1Z85A 3KW2A 3IC6A 4JALA 4H3YA 4CNGA 3AIAA 4YQCA 4YQ7A 2V3KA 2QMMA 4YPYA 2YY8A 1V2XA 4KDZA 5GMCA 5GM8A 3ONPA 3BBEA 4JAKA 3NK6A 1P9PA 5GMBA 2I6DA 1J85A 3QUVA 1K3RA 4MCCA 4YQKA 3KTYA 2EGVA 2Z0YA 2HA8A 4X3LA 1ZJRA 3BBHA 4IG6A 3DCMX 4YVJA 4YQIA 5CO4A 4YVGA 4YVHA 4YQ9A 1X7OA 3O7BA 2QWVA 1UALA 1NXZA 3E5YA 4MCDA 4X3MA 4YVKA 4YQ5A 1UAMA 4YQAA 1VHYA 1NS5A 1UAKA 4YQOA 4YPZA 1UAJA 2O3AA 4YQJA 4J3CA 4YQBA 1OY5A 3BBDA 3N4JA 4RG1A 4YQ8A 3L8UA 1V6ZA 4YPXA 5FAIA 4YQ4A 2V3JA 4YVIA 1O6DA 2CX8A 4L69A 4XBOA 4E8BA 4YQ2A 4YQPA 3KY7A 1VH0A 3GYQA 2EGWA 4KGNA 4CNEA 5D9FA 4MCBA 4YQ3A 4YQNA 3NK7A 4YQQA 1GZ0A 4YPWA 4YQ0A 3OIJA 3OIIA 4YQLA 1MXIA 4YQ6A 3AXZA 4CNDA 3KNUA 1VHKA
chains in the Genus database with same CATH superfamily
1X7PA 4H3ZA 4YQTA 3ILKA 4CNFA 4YQRA 4FAKA 4YQ1A 4YQGA 3OINA 3IEFA 1IPAA 3N4KA 3AI9X 4YQDA 4PZKA 1TO0A 4YQSA 4JWHA 1Z85A 4FMWA 3KW2A 3IC6A 4JALA 4H3YA 4CNGA 3AIAA 4YQCA 4YQ7A 2V3KA 2QMMA 4YPYA 2YY8A 1V2XA 4KDZA 5GMCA 5GM8A 3ONPA 3BBEA 4JAKA 3NK6A 1P9PA 5GMBA 2I6DA 1J85A 3QUVA 1K3RA 4MCCA 4YQKA 3KTYA 2EGVA 2Z0YA 2HA8A 4X3LA 1ZJRA 3BBHA 4IG6A 3DCMX 4YVJA 4YQIA 5CO4A 4YVGA 4YVHA 4JWFA 4YQ9A 1X7OA 3O7BA 2QWVA 1UALA 1NXZA 3E5YA 4MCDA 4X3MA 4YVKA 4YQ5A 1UAMA 4YQAA 1VHYA 4JWJA 1NS5A 1UAKA 4YQOA 4YPZA 1UAJA 2O3AA 4YQJA 4J3CA 4YQBA 1OY5A 3BBDA 3N4JA 4RG1A 4YQ8A 3L8UA 1V6ZA 4YPXA 5FAIA 4YQ4A 2V3JA 4YVIA 1O6DA 2CX8A 4L69A 4XBOA 4E8BA 4YQ2A 4YQPA 3KY7A 4JWGA 1VH0A 3GYQA 2EGWA 4KGNA 4CNEA 5D9FA 4MCBA 4YQ3A 4YQNA 3NK7A 4YQQA 1GZ0A 4YPWA 4YQ0A 3OIJA 3OIIA 4YQLA 1MXIA 4YQ6A 3AXZA 4CNDA 3KNUA 1VHKA
chains in the Genus database with same CATH topology
1X7PA 4H3ZA 4YQTA 3ILKA 4CNFA 4YQRA 4FAKA 4YQ1A 4YQGA 3OINA 3IEFA 1IPAA 3N4KA 3AI9X 4YQDA 4PZKA 1TO0A 4YQSA 4JWHA 1Z85A 4FMWA 3KW2A 3IC6A 4JALA 4H3YA 4CNGA 3AIAA 4YQCA 4YQ7A 2V3KA 2QMMA 4YPYA 2YY8A 1V2XA 4KDZA 5GMCA 5GM8A 3ONPA 3BBEA 4JAKA 3NK6A 1P9PA 5GMBA 2I6DA 1J85A 3QUVA 1K3RA 4MCCA 4YQKA 3KTYA 2EGVA 2Z0YA 2HA8A 4X3LA 1ZJRA 3BBHA 4IG6A 3DCMX 4YVJA 4YQIA 5CO4A 4YVGA 4YVHA 4JWFA 4YQ9A 1X7OA 3O7BA 2QWVA 1UALA 1NXZA 3E5YA 4MCDA 4X3MA 4YVKA 4YQ5A 1UAMA 4YQAA 1VHYA 4JWJA 1NS5A 1UAKA 4YQOA 4YPZA 1UAJA 2O3AA 4YQJA 4J3CA 4YQBA 1OY5A 3BBDA 3N4JA 4RG1A 4YQ8A 3L8UA 1V6ZA 4YPXA 5FAIA 4YQ4A 2V3JA 4YVIA 1O6DA 2CX8A 4L69A 4XBOA 4E8BA 4YQ2A 4YQPA 3KY7A 4JWGA 1VH0A 3GYQA 2EGWA 4KGNA 4CNEA 5D9FA 4MCBA 4YQ3A 4YQNA 3NK7A 4YQQA 1GZ0A 4YPWA 4YQ0A 3OIJA 3OIIA 4YQLA 1MXIA 4YQ6A 3AXZA 4CNDA 3KNUA 1VHKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X7P A;  4H3Z A;  4YQT A;  3ILK A;  4CNF A;  4YQR A;  4FAK A;  4YQ1 A;  4YQG A;  3OIN A;  3IEF A;  1IPA A;  3N4K A;  3AI9 X;  4YQD A;  4PZK A;  1TO0 A;  4YQS A;  1Z85 A;  3KW2 A;  3IC6 A;  4JAL A;  4H3Y A;  4CNG A;  3AIA A;  4YQC A;  4YQ7 A;  2V3K A;  2QMM A;  4YPY A;  2YY8 A;  1V2X A;  4KDZ A;  5GMC A;  5GM8 A;  3ONP A;  3BBE A;  4JAK A;  3NK6 A;  1P9P A;  5GMB A;  2I6D A;  1J85 A;  3QUV A;  1K3R A;  4MCC A;  4YQK A;  3KTY A;  2EGV A;  2Z0Y A;  2HA8 A;  4X3L A;  1ZJR A;  3BBH A;  4IG6 A;  3DCM X;  4YVJ A;  4YQI A;  5CO4 A;  4YVG A;  4YVH A;  4YQ9 A;  1X7O A;  3O7B A;  2QWV A;  1UAL A;  1NXZ A;  3E5Y A;  4MCD A;  4X3M A;  4YVK A;  4YQ5 A;  1UAM A;  4YQA A;  1VHY A;  1NS5 A;  1UAK A;  4YQO A;  4YPZ A;  1UAJ A;  2O3A A;  4YQJ A;  4J3C A;  4YQB A;  1OY5 A;  3BBD A;  3N4J A;  4RG1 A;  4YQ8 A;  3L8U A;  1V6Z A;  4YPX A;  5FAI A;  4YQ4 A;  2V3J A;  4YVI A;  1O6D A;  2CX8 A;  4L69 A;  4XBO A;  4E8B A;  4YQ2 A;  4YQP A;  3KY7 A;  1VH0 A;  3GYQ A;  2EGW A;  4KGN A;  4CNE A;  5D9F A;  4MCB A;  4YQ3 A;  4YQN A;  3NK7 A;  4YQQ A;  1GZ0 A;  4YPW A;  4YQ0 A;  3OIJ A;  3OII A;  4YQL A;  1MXI A;  4YQ6 A;  3AXZ A;  4CND A;  3KNU A;  1VHK A; 
#chains in the Genus database with same CATH topology
 1X7P A;  4H3Z A;  4YQT A;  3ILK A;  4CNF A;  4YQR A;  4FAK A;  4YQ1 A;  4YQG A;  3OIN A;  3IEF A;  1IPA A;  3N4K A;  3AI9 X;  4YQD A;  4PZK A;  1TO0 A;  4YQS A;  4JWH A;  1Z85 A;  4FMW A;  3KW2 A;  3IC6 A;  4JAL A;  4H3Y A;  4CNG A;  3AIA A;  4YQC A;  4YQ7 A;  2V3K A;  2QMM A;  4YPY A;  2YY8 A;  1V2X A;  4KDZ A;  5GMC A;  5GM8 A;  3ONP A;  3BBE A;  4JAK A;  3NK6 A;  1P9P A;  5GMB A;  2I6D A;  1J85 A;  3QUV A;  1K3R A;  4MCC A;  4YQK A;  3KTY A;  2EGV A;  2Z0Y A;  2HA8 A;  4X3L A;  1ZJR A;  3BBH A;  4IG6 A;  3DCM X;  4YVJ A;  4YQI A;  5CO4 A;  4YVG A;  4YVH A;  4JWF A;  4YQ9 A;  1X7O A;  3O7B A;  2QWV A;  1UAL A;  1NXZ A;  3E5Y A;  4MCD A;  4X3M A;  4YVK A;  4YQ5 A;  1UAM A;  4YQA A;  1VHY A;  4JWJ A;  1NS5 A;  1UAK A;  4YQO A;  4YPZ A;  1UAJ A;  2O3A A;  4YQJ A;  4J3C A;  4YQB A;  1OY5 A;  3BBD A;  3N4J A;  4RG1 A;  4YQ8 A;  3L8U A;  1V6Z A;  4YPX A;  5FAI A;  4YQ4 A;  2V3J A;  4YVI A;  1O6D A;  2CX8 A;  4L69 A;  4XBO A;  4E8B A;  4YQ2 A;  4YQP A;  3KY7 A;  4JWG A;  1VH0 A;  3GYQ A;  2EGW A;  4KGN A;  4CNE A;  5D9F A;  4MCB A;  4YQ3 A;  4YQN A;  3NK7 A;  4YQQ A;  1GZ0 A;  4YPW A;  4YQ0 A;  3OIJ A;  3OII A;  4YQL A;  1MXI A;  4YQ6 A;  3AXZ A;  4CND A;  3KNU A;  1VHK A; 
#chains in the Genus database with same CATH homology
 1X7P A;  4H3Z A;  4YQT A;  3ILK A;  4CNF A;  4YQR A;  4FAK A;  4YQ1 A;  4YQG A;  3OIN A;  3IEF A;  1IPA A;  3N4K A;  3AI9 X;  4YQD A;  4PZK A;  1TO0 A;  4YQS A;  4JWH A;  1Z85 A;  4FMW A;  3KW2 A;  3IC6 A;  4JAL A;  4H3Y A;  4CNG A;  3AIA A;  4YQC A;  4YQ7 A;  2V3K A;  2QMM A;  4YPY A;  2YY8 A;  1V2X A;  4KDZ A;  5GMC A;  5GM8 A;  3ONP A;  3BBE A;  4JAK A;  3NK6 A;  1P9P A;  5GMB A;  2I6D A;  1J85 A;  3QUV A;  1K3R A;  4MCC A;  4YQK A;  3KTY A;  2EGV A;  2Z0Y A;  2HA8 A;  4X3L A;  1ZJR A;  3BBH A;  4IG6 A;  3DCM X;  4YVJ A;  4YQI A;  5CO4 A;  4YVG A;  4YVH A;  4JWF A;  4YQ9 A;  1X7O A;  3O7B A;  2QWV A;  1UAL A;  1NXZ A;  3E5Y A;  4MCD A;  4X3M A;  4YVK A;  4YQ5 A;  1UAM A;  4YQA A;  1VHY A;  4JWJ A;  1NS5 A;  1UAK A;  4YQO A;  4YPZ A;  1UAJ A;  2O3A A;  4YQJ A;  4J3C A;  4YQB A;  1OY5 A;  3BBD A;  3N4J A;  4RG1 A;  4YQ8 A;  3L8U A;  1V6Z A;  4YPX A;  5FAI A;  4YQ4 A;  2V3J A;  4YVI A;  1O6D A;  2CX8 A;  4L69 A;  4XBO A;  4E8B A;  4YQ2 A;  4YQP A;  3KY7 A;  4JWG A;  1VH0 A;  3GYQ A;  2EGW A;  4KGN A;  4CNE A;  5D9F A;  4MCB A;  4YQ3 A;  4YQN A;  3NK7 A;  4YQQ A;  1GZ0 A;  4YPW A;  4YQ0 A;  3OIJ A;  3OII A;  4YQL A;  1MXI A;  4YQ6 A;  3AXZ A;  4CND A;  3KNU A;  1VHK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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