1ZM8A

Apo crystal structure of nuclease a from anabaena sp.
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
239
structure length
239
Chain Sequence
ISVHLLLGNPSGATPTKLTPDNYLMVKNQYALSYNNSKGTANWVAWQLNSSWLGNAERQDNFRPDKTLPAGWVRVTPSMYSGSGYARGHIAPSADRTKTTEDNAATFLMTNMMPQTPDNNRNTWGNLEDYCRELVSQGKELYIVAGPNGSLGKPLKGKVTVPKSTWKIVVVLDSPGSGLEGITANTRVIAVNIPNDPELNNDWRAYKVSVDELESLTGYDFLSNVSPNIQTSIESKVDN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Mechanism of Nuclease A, a beta beta alpha Metal Nuclease from Anabaena.
pubmed doi rcsb
source organism Anabaena sp.
molecule tags Hydrolase
molecule keywords Nuclease
total genus 72
structure length 239
sequence length 239
ec nomenclature ec 3.1.30.-:
pdb deposition date 2005-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 1zm8A00
3S5BA 2XGRA 3WAYA 4E3YA 5L0KA 4QH0A 4QN0A 4ZG6A 1QL0A 3OWVA 3NKPA 5DLTA 4QGOA 5GKPA 4ZG7A 4A1NA 2XRGA 3ISMA 3NKOA 3NKQA 2XH3A 1G8TA 5LQQA 3WAWA 2O3BA 2XR9A 5L0EA 5IJQA 3NKRA 1SMNA 4ZG9A 5LIAA 5HRTA 5DLVA 4GTXA 5INHA 1QAEA 5GKCA 4GTYA 3NKMA 4GTWA 3NKNA 4GTZA 4ZGAA 1ZM8A 5DLWA 3WAXA 5KXAA 5IJSA 5L0BA 4B56A 3WAVA
chains in the Genus database with same CATH superfamily
3S5BA 2XGRA 3WAYA 4E3YA 5L0KA 4QH0A 4QN0A 4ZG6A 1QL0A 3OWVA 3NKPA 5DLTA 4QGOA 5GKPA 4ZG7A 4A1NA 2XRGA 3ISMA 3NKOA 3NKQA 2XH3A 1G8TA 5LQQA 3WAWA 2O3BA 2XR9A 5L0EA 5IJQA 3NKRA 1SMNA 4ZG9A 5LIAA 5HRTA 5DLVA 4GTXA 5INHA 1QAEA 5GKCA 4GTYA 3NKMA 4GTWA 3NKNA 4GTZA 4ZGAA 1ZM8A 5DLWA 3WAXA 5KXAA 5IJSA 5L0BA 4B56A 3WAVA
chains in the Genus database with same CATH topology
3S5BA 2XGRA 3WAYA 4E3YA 5L0KA 4QH0A 4QN0A 4ZG6A 1QL0A 3OWVA 3NKPA 5DLTA 4QGOA 5GKPA 4ZG7A 4A1NA 2XRGA 3ISMA 3NKOA 3NKQA 2XH3A 1G8TA 5LQQA 3WAWA 2O3BA 2XR9A 5L0EA 5IJQA 3NKRA 1SMNA 4ZG9A 5LIAA 5HRTA 5DLVA 4GTXA 5INHA 1QAEA 5GKCA 4GTYA 3NKMA 4GTWA 3NKNA 4GTZA 4ZGAA 1ZM8A 5DLWA 3WAXA 5KXAA 5IJSA 5L0BA 4B56A 3WAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S5B A;  2XGR A;  3WAY A;  4E3Y A;  5L0K A;  4QH0 A;  4QN0 A;  4ZG6 A;  1QL0 A;  3OWV A;  3NKP A;  5DLT A;  4QGO A;  5GKP A;  4ZG7 A;  4A1N A;  2XRG A;  3ISM A;  3NKO A;  3NKQ A;  2XH3 A;  1G8T A;  5LQQ A;  3WAW A;  2O3B A;  2XR9 A;  5L0E A;  5IJQ A;  3NKR A;  1SMN A;  4ZG9 A;  5LIA A;  5HRT A;  5DLV A;  4GTX A;  5INH A;  1QAE A;  5GKC A;  4GTY A;  3NKM A;  4GTW A;  3NKN A;  4GTZ A;  4ZGA A;  1ZM8 A;  5DLW A;  3WAX A;  5KXA A;  5IJS A;  5L0B A;  4B56 A;  3WAV A; 
#chains in the Genus database with same CATH topology
 3S5B A;  2XGR A;  3WAY A;  4E3Y A;  5L0K A;  4QH0 A;  4QN0 A;  4ZG6 A;  1QL0 A;  3OWV A;  3NKP A;  5DLT A;  4QGO A;  5GKP A;  4ZG7 A;  4A1N A;  2XRG A;  3ISM A;  3NKO A;  3NKQ A;  2XH3 A;  1G8T A;  5LQQ A;  3WAW A;  2O3B A;  2XR9 A;  5L0E A;  5IJQ A;  3NKR A;  1SMN A;  4ZG9 A;  5LIA A;  5HRT A;  5DLV A;  4GTX A;  5INH A;  1QAE A;  5GKC A;  4GTY A;  3NKM A;  4GTW A;  3NKN A;  4GTZ A;  4ZGA A;  1ZM8 A;  5DLW A;  3WAX A;  5KXA A;  5IJS A;  5L0B A;  4B56 A;  3WAV A; 
#chains in the Genus database with same CATH homology
 3S5B A;  2XGR A;  3WAY A;  4E3Y A;  5L0K A;  4QH0 A;  4QN0 A;  4ZG6 A;  1QL0 A;  3OWV A;  3NKP A;  5DLT A;  4QGO A;  5GKP A;  4ZG7 A;  4A1N A;  2XRG A;  3ISM A;  3NKO A;  3NKQ A;  2XH3 A;  1G8T A;  5LQQ A;  3WAW A;  2O3B A;  2XR9 A;  5L0E A;  5IJQ A;  3NKR A;  1SMN A;  4ZG9 A;  5LIA A;  5HRT A;  5DLV A;  4GTX A;  5INH A;  1QAE A;  5GKC A;  4GTY A;  3NKM A;  4GTW A;  3NKN A;  4GTZ A;  4ZGA A;  1ZM8 A;  5DLW A;  3WAX A;  5KXA A;  5IJS A;  5L0B A;  4B56 A;  3WAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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