1ZYMA

Amino terminal domain of enzyme i from escherichia coli
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
247
structure length
247
Chain Sequence
SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
molecule keywords ENZYME I
total genus 80
structure length 247
sequence length 247
chains with identical sequence B
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1996-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1zymA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1zymA01
3EZBA 1EZAA 5JVLA 2EZBA 1KBLA 2HROA 1JDEA 2DIKA 3T0TA 2E28A 3T07A 3T05A 2EZAA 1VBGA 1ZYMA 2MP0A 1VBHA 1GGOA 1DIKA 2HI6A 2FM4A 1KC7A 1EZBA 2X0SA 2EZCA 3EZAA 2OLSA 2R82A 3EZEA 2HWGA
chains in the Genus database with same CATH superfamily
3GTQA 4OC5A 4W9YA 1KEEB 4P4IA 2EZBA 4JYWA 4NGTA 1R9TA 3GTOA 1XF1A 2C6GA 2OOTA 2LPIA 4C9AA 3LR2A 4C8AA 1JDEA 3D7FA 3C8OA 4INJA 3U44A 5JYBA 4MCQA 4J0NA 1ZRSA 2BE5D 2PVVA 1NBWA 1CE8B 4NGMA 2A6HD 2FIPA 5D29A 3CQZA 1Q5XA 2XEFA 1T6JA 3NZ4A 4MCRA 3T5MA 2EZAA 5F1YA 4OMEA 5FD8A 4IIXA 3TYXA 4C86A 4CZ1A 3LRDA 1T36B 1VBHA 2CW0D 4LQGA 3SR3A 2JA7A 2C5QA 4BAAA 4P4JA 2MQAA 4M8DA 4C9EA 2HI6A 2A69D 3H0GA 2O5JD 4COGA 1TWAA 2A6ED 4C8TA 3U4QA 2JA6A 1Y2MA 3EZAA 2GP4A 2NVXA 3FF3A 4MCSA 4C8CA 2R82A 2OLSA 1BXRB 2NVYA 5IZ2A 4P4FA 3KASA 2YU9A 2YJVA 2MX8A 1HQMD 2LTHA 4C5UA 3GTKA 5JVLA 4CDKA 4TJXA 1KBLA 2R92A 2HROA 2Y0NA 3GTGA 4NGNA 4OC4A 1W27A 2JBKA 1TWCA 4CEJA 1WVMA 3K4IA 2N3EA 2DIKA 3SJEA 3T0TA 3D7HA 4OC0A 3T07A 4V2RA 2B0AA 1TWGA 4C8PA 4EYSA 3U1BA 2K3QA 1IW7D 1C3OB 1ZL0A 3GJZA 4C9RA 3FEDA 4P4EA 4C5RA 4JVOA 3I74A 4P44A 2LPJA 3GTLA 1J3LA 2YIIA 1GGOA 2MX9A 2F5JA 3GTMA 5ELYA 1VI4A 1SMYD 1EZBA 2X0SA 2E2HA 4KNGE 2EZCA 1Y9ZA 2PVWA 3RBUA 3TLAA 2C6CA 4C84A 2JBJA 3SJFA 2LKMB 2XEIA 4C5SA 3FEEA 3EZEA 2R7ZA 3G23A 2K3NA 3IWWA 4CO9A 4C9UA 3S9LA 1TWHA 4C6GA 4H1HA 4E5SA 3ICUA 3BI1A 1ZYRD 3SJXA 2X0OA 1I50A 3D7GA 2VK9A 1JDBC 4NGQA 4OC2A 2LYIA 4OC3A 1TWFA 2OR4A 4MI1A 3GTPA 4OC1A 2XEGA 3SJGA 4FBSA 3BI0A 1SFOA 5F5XA 2PCNA 1A9XB 3T05A 2X0PA 4TJVA 5F09A 1YNND 1VBGA 4P4BA 2EK9A 3GTJA 4C9VA 4C85A 2MP0A 4QIWA 3EIFA 4C99A 3LR8A 2A68D 1K83A 3BXMA 3KRVA 3K9TA 2AUMA 5F9MA 1T6PA 2JA5A 2FM4A 3TLZA 2C6PA 1KC7A 3TLBA 2AQLA 2D0OA 1C30B 4E94A 4CEIA 2D0PA 2HWGA 3TLYA 3EZBA 4X3RA 1EZAA 4COBA 5K99A 2N1DB 2YJTA 4NGSA 3FKIA 4BABA 3S9NA 4C2MA 1I3QA 1R61A 4V2QA 4NGRA 1CX8A 1DE4C 1CS0B 2XEJA 3VTAA 2EK8A 4P45A 2CIJA 2E28A 4MCPA 4YN3A 3TLGB 3LR6A 3NOJA 3S9MA 4C8FA 2VUMA 4C8UA 2R93A 1M6VB 1ZYMA 2K3OA 4CQ5A 2AUNA 4CDJA 3TLGA 4MJXA 2B63A 3FECA 3I6SA 3TLEA 1YNJD 4JZ0A 1V6CA 4P4DA 2FIOA 2E2IA 1DIKA 4IIYA 4CEHA 2X0QA 1NXJA 1Y1WA 4TWEA 1WCMA 4NGPA 1Z8LA 1Y1VA 5IR2A 3TLCA 5IB9A 3D7DA 3IIBA 1I6VD 3BHXA
chains in the Genus database with same CATH topology
3EZBA 1EZAA 5JVLA 2EZBA 1KBLA 2HROA 1JDEA 2DIKA 3T0TA 2E28A 3T07A 3T05A 2EZAA 1VBGA 1ZYMA 2MP0A 1VBHA 1GGOA 1DIKA 2HI6A 2FM4A 1KC7A 1EZBA 2X0SA 2EZCA 3EZAA 2OLSA 2R82A 3EZEA 2HWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZB A;  1EZA A;  5JVL A;  2EZB A;  1KBL A;  2HRO A;  1JDE A;  2DIK A;  3T0T A;  2E28 A;  3T07 A;  3T05 A;  2EZA A;  1VBG A;  1ZYM A;  2MP0 A;  1VBH A;  1GGO A;  1DIK A;  2HI6 A;  2FM4 A;  1KC7 A;  1EZB A;  2X0S A;  2EZC A;  3EZA A;  2OLS A;  2R82 A;  3EZE A;  2HWG A; 
#chains in the Genus database with same CATH topology
 3GTQ A;  4OC5 A;  4W9Y A;  1KEE B;  4P4I A;  2EZB A;  4JYW A;  4NGT A;  1R9T A;  3GTO A;  1XF1 A;  2C6G A;  2OOT A;  2LPI A;  4C9A A;  3LR2 A;  4C8A A;  1JDE A;  3D7F A;  3C8O A;  4INJ A;  3U44 A;  5JYB A;  4MCQ A;  4J0N A;  1ZRS A;  2BE5 D;  2PVV A;  1NBW A;  1CE8 B;  4NGM A;  2A6H D;  2FIP A;  5D29 A;  3CQZ A;  1Q5X A;  2XEF A;  1T6J A;  3NZ4 A;  4MCR A;  3T5M A;  2EZA A;  5F1Y A;  4OME A;  5FD8 A;  4IIX A;  3TYX A;  4C86 A;  4CZ1 A;  3LRD A;  1T36 B;  1VBH A;  2CW0 D;  4LQG A;  3SR3 A;  2JA7 A;  2C5Q A;  4BAA A;  4P4J A;  2MQA A;  4M8D A;  4C9E A;  2HI6 A;  2A69 D;  3H0G A;  2O5J D;  4COG A;  1TWA A;  2A6E D;  4C8T A;  3U4Q A;  2JA6 A;  1Y2M A;  3EZA A;  2GP4 A;  2NVX A;  3FF3 A;  4MCS A;  4C8C A;  2R82 A;  2OLS A;  1BXR B;  2NVY A;  5IZ2 A;  4P4F A;  3KAS A;  2YU9 A;  2YJV A;  2MX8 A;  1HQM D;  2LTH A;  4C5U A;  3GTK A;  5JVL A;  4CDK A;  4TJX A;  1KBL A;  2R92 A;  2HRO A;  2Y0N A;  3GTG A;  4NGN A;  4OC4 A;  1W27 A;  2JBK A;  1TWC A;  4CEJ A;  1WVM A;  3K4I A;  2N3E A;  2DIK A;  3SJE A;  3T0T A;  3D7H A;  4OC0 A;  3T07 A;  4V2R A;  2B0A A;  1TWG A;  4C8P A;  4EYS A;  3U1B A;  2K3Q A;  1IW7 D;  1C3O B;  1ZL0 A;  3GJZ A;  4C9R A;  3FED A;  4P4E A;  4C5R A;  4JVO A;  3I74 A;  4P44 A;  2LPJ A;  3GTL A;  1J3L A;  2YII A;  1GGO A;  2MX9 A;  2F5J A;  3GTM A;  5ELY A;  1VI4 A;  1SMY D;  1EZB A;  2X0S A;  2E2H A;  4KNG E;  2EZC A;  1Y9Z A;  2PVW A;  3RBU A;  3TLA A;  2C6C A;  4C84 A;  2JBJ A;  3SJF A;  2LKM B;  2XEI A;  4C5S A;  3FEE A;  3EZE A;  2R7Z A;  3G23 A;  2K3N A;  3IWW A;  4CO9 A;  4C9U A;  3S9L A;  1TWH A;  4C6G A;  4H1H A;  4E5S A;  3ICU A;  3BI1 A;  1ZYR D;  3SJX A;  2X0O A;  1I50 A;  3D7G A;  2VK9 A;  1JDB C;  4NGQ A;  4OC2 A;  2LYI A;  4OC3 A;  1TWF A;  2OR4 A;  4MI1 A;  3GTP A;  4OC1 A;  2XEG A;  3SJG A;  4FBS A;  3BI0 A;  1SFO A;  5F5X A;  2PCN A;  1A9X B;  3T05 A;  2X0P A;  4TJV A;  5F09 A;  1YNN D;  1VBG A;  4P4B A;  2EK9 A;  3GTJ A;  4C9V A;  4C85 A;  2MP0 A;  4QIW A;  3EIF A;  4C99 A;  3LR8 A;  2A68 D;  1K83 A;  3BXM A;  3KRV A;  3K9T A;  2AUM A;  5F9M A;  1T6P A;  2JA5 A;  2FM4 A;  3TLZ A;  2C6P A;  1KC7 A;  3TLB A;  2AQL A;  2D0O A;  1C30 B;  4E94 A;  4CEI A;  2D0P A;  2HWG A;  3TLY A;  3EZB A;  4X3R A;  1EZA A;  4COB A;  5K99 A;  2N1D B;  2YJT A;  4NGS A;  3FKI A;  4BAB A;  3S9N A;  4C2M A;  1I3Q A;  1R61 A;  4V2Q A;  4NGR A;  1CX8 A;  1DE4 C;  1CS0 B;  2XEJ A;  3VTA A;  2EK8 A;  4P45 A;  2CIJ A;  2E28 A;  4MCP A;  4YN3 A;  3TLG B;  3LR6 A;  3NOJ A;  3S9M A;  4C8F A;  2VUM A;  4C8U A;  2R93 A;  1M6V B;  1ZYM A;  2K3O A;  4CQ5 A;  2AUN A;  4CDJ A;  3TLG A;  4MJX A;  2B63 A;  3FEC A;  3I6S A;  3TLE A;  1YNJ D;  4JZ0 A;  1V6C A;  4P4D A;  2FIO A;  2E2I A;  1DIK A;  4IIY A;  4CEH A;  2X0Q A;  1NXJ A;  1Y1W A;  4TWE A;  1WCM A;  4NGP A;  1Z8L A;  1Y1V A;  5IR2 A;  3TLC A;  5IB9 A;  3D7D A;  3IIB A;  1I6V D;  3BHX A; 
#chains in the Genus database with same CATH homology
 3EZB A;  1EZA A;  5JVL A;  2EZB A;  1KBL A;  2HRO A;  1JDE A;  2DIK A;  3T0T A;  2E28 A;  3T07 A;  3T05 A;  2EZA A;  1VBG A;  1ZYM A;  2MP0 A;  1VBH A;  1GGO A;  1DIK A;  2HI6 A;  2FM4 A;  1KC7 A;  1EZB A;  2X0S A;  2EZC A;  3EZA A;  2OLS A;  2R82 A;  3EZE A;  2HWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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