1ZYMA

Amino terminal domain of enzyme i from escherichia coli
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
247
structure length
247
Chain Sequence
b'SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ENZYME I
publication title The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 80
structure length 247
sequence length 247
chains with identical sequence B
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1996-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1zymA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1zymA01
1JDEA 2FM4A 1ZYMA 3T05A 2MP0A 3EZAA 1GGOA 3T07A 3T0TA 2HROA 2HWGA 3EZBA 1EZAA 2OLSA 2X0SA 2EZAA 1VBGA 2R82A 2E28A 2EZBA 1VBHA 1KBLA 3EZEA 2EZCA 2DIKA 1KC7A 5JVLA 1EZBA 1DIKA 2HI6A
chains in the Genus database with same CATH superfamily
1JDEA 1R61A 4OC1A 3LRDA 2PCNA 2E2HA 4COBA 4C2MA 1TWFA 2X0OA 4C8PA 3H0GA 1CS0B 4KNGE 4FBSA 4MCQA 1DE4C 3S9NA 1HQMD 1I50A 2JBKA 3FECA 1ZYRD 5IZ2A 4NGQA 2MP0A 3U1BA 3BXMA 2EK8A 2XEGA 4E5SA 2VUMA 3TLBA 3G23A 3EZBA 3KASA 2A68D 4C84A 3SJFA 4BAAA 3NOJA 3TLAA 4H1HA 4TWEA 1J3LA 1Z8LA 4C9VA 1Y9ZA 4W9YA 2K3OA 3D7HA 1JDBC 4NGSA 1T6JA 4NGPA 1EZAA 2OLSA 4LQGA 4CQ5A 4C9EA 4MCSA 2MX8A 1DIKA 3T05A 2FM4A 4C99A 3EZAA 3RBUA 4P4BA 4MCPA 4C9UA 2YJVA 2X0PA 4CZ1A 3CQZA 2MX9A 1VBGA 2A6HD 1C30B 4M8DA 1KBLA 4P4IA 4OC2A 4QIWA 4NGNA 4C85A 4INJA 2JBJA 4C86A 1CE8B 4OMEA 1W27A 3EZEA 1EZBA 2F5JA 2YU9A 3K4IA 2VK9A 3T5MA 3GTLA 3SR3A 4MCRA 4BABA 2PVVA 2LPIA 2X0SA 2N1DB 2GP4A 2YJTA 4E94A 3VTAA 1Y1WA 4P4FA 2NVXA 3U4QA 4C8TA 2JA6A 4P4EA 4V2QA 4C8AA 1I6VD 1Y2MA 2E2IA 5IB9A 4IIYA 3D7DA 3S9LA 3IIBA 2LPJA 1SFOA 5D29A 1TWGA 5IR2A 4YN3A 2AUNA 4C8FA 1V6CA 2OR4A 4P4JA 1TWAA 4COGA 5FD8A 5K99A 4JVOA 2LTHA 4NGTA 3TLYA 3U44A 3GTMA 1YNND 2XEJA 1I3QA 1VI4A 4CDJA 3LR2A 1SMYD 3GTGA 3IWWA 2LKMB 2D0OA 4X3RA 2C6GA 2R93A 4IIXA 2EZBA 3LR6A 2A6ED 2O5JD 3SJXA 2K3QA 4P44A 2XEIA 3TLCA 4C6GA 4MJXA 3GTPA 4JZ0A 4P45A 1KEEB 3FEEA 3SJEA 3C8OA 2C6PA 2AQLA 4OC3A 1Y1VA 3TLZA 2N3EA 2JA5A 2EK9A 1WCMA 2K3NA 1Q5XA 2E28A 3EIFA 2NVYA 1K83A 1XF1A 1NBWA 1KC7A 3S9MA 4C8CA 4TJXA 2Y0NA 1YNJD 4J0NA 3KRVA 3TLEA 4MI1A 2AUMA 3BI0A 3BHXA 1T6PA 3BI1A 4C5RA 2XEFA 5F1YA 2MQAA 3TLGB 1ZYMA 3FEDA 3K9TA 4V2RA 3GTJA 3FF3A 2X0QA 3SJGA 2HWGA 4OC4A 2C5QA 3I6SA 3TLGA 2EZAA 2R7ZA 2FIPA 2OOTA 4C5SA 5F5XA 5JYBA 1TWHA 2C6CA 1WVMA 4C5UA 3D7FA 3T07A 3D7GA 1T36B 4C8UA 2R82A 3NZ4A 1ZRSA 2DIKA 2B0AA 4OC5A 4CEIA 2EZCA 2A69D 2D0PA 3TYXA 3GTOA 4C9RA 4CEHA 2HROA 1R9TA 3GJZA 2LYIA 4C9AA 4CDKA 1NXJA 2BE5D 2HI6A 1BXRB 4CO9A 1CX8A 3FKIA 4NGMA 2R92A 5F09A 1C3OB 4NGRA 1VBHA 5JVLA 1ZL0A 3LR8A 3ICUA 4OC0A 2YIIA 4TJVA 1TWCA 1GGOA 1M6VB 3T0TA 4P4DA 3GTKA 5F9MA 1A9XB 1IW7D 5ELYA 2FIOA 4CEJA 2B63A 3I74A 3GTQA 2CIJA 4JYWA 4EYSA 2JA7A 2PVWA 2CW0D
chains in the Genus database with same CATH topology
1JDEA 2FM4A 1ZYMA 3T05A 2MP0A 3EZAA 1GGOA 3T07A 3T0TA 2HROA 2HWGA 3EZBA 1EZAA 2OLSA 2X0SA 2EZAA 1VBGA 2R82A 2E28A 2EZBA 1VBHA 1KBLA 3EZEA 2EZCA 2DIKA 1KC7A 5JVLA 1EZBA 1DIKA 2HI6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JDE A;  2FM4 A;  1ZYM A;  3T05 A;  2MP0 A;  3EZA A;  1GGO A;  3T07 A;  3T0T A;  2HRO A;  2HWG A;  3EZB A;  1EZA A;  2OLS A;  2X0S A;  2EZA A;  1VBG A;  2R82 A;  2E28 A;  2EZB A;  1VBH A;  1KBL A;  3EZE A;  2EZC A;  2DIK A;  1KC7 A;  5JVL A;  1EZB A;  1DIK A;  2HI6 A; 
#chains in the Genus database with same CATH topology
 1JDE A;  1R61 A;  4OC1 A;  3LRD A;  2PCN A;  2E2H A;  4COB A;  4C2M A;  1TWF A;  2X0O A;  4C8P A;  3H0G A;  1CS0 B;  4KNG E;  4FBS A;  4MCQ A;  1DE4 C;  3S9N A;  1HQM D;  1I50 A;  2JBK A;  3FEC A;  1ZYR D;  5IZ2 A;  4NGQ A;  2MP0 A;  3U1B A;  3BXM A;  2EK8 A;  2XEG A;  4E5S A;  2VUM A;  3TLB A;  3G23 A;  3EZB A;  3KAS A;  2A68 D;  4C84 A;  3SJF A;  4BAA A;  3NOJ A;  3TLA A;  4H1H A;  4TWE A;  1J3L A;  1Z8L A;  4C9V A;  1Y9Z A;  4W9Y A;  2K3O A;  3D7H A;  1JDB C;  4NGS A;  1T6J A;  4NGP A;  1EZA A;  2OLS A;  4LQG A;  4CQ5 A;  4C9E A;  4MCS A;  2MX8 A;  1DIK A;  3T05 A;  2FM4 A;  4C99 A;  3EZA A;  3RBU A;  4P4B A;  4MCP A;  4C9U A;  2YJV A;  2X0P A;  4CZ1 A;  3CQZ A;  2MX9 A;  1VBG A;  2A6H D;  1C30 B;  4M8D A;  1KBL A;  4P4I A;  4OC2 A;  4QIW A;  4NGN A;  4C85 A;  4INJ A;  2JBJ A;  4C86 A;  1CE8 B;  4OME A;  1W27 A;  3EZE A;  1EZB A;  2F5J A;  2YU9 A;  3K4I A;  2VK9 A;  3T5M A;  3GTL A;  3SR3 A;  4MCR A;  4BAB A;  2PVV A;  2LPI A;  2X0S A;  2N1D B;  2GP4 A;  2YJT A;  4E94 A;  3VTA A;  1Y1W A;  4P4F A;  2NVX A;  3U4Q A;  4C8T A;  2JA6 A;  4P4E A;  4V2Q A;  4C8A A;  1I6V D;  1Y2M A;  2E2I A;  5IB9 A;  4IIY A;  3D7D A;  3S9L A;  3IIB A;  2LPJ A;  1SFO A;  5D29 A;  1TWG A;  5IR2 A;  4YN3 A;  2AUN A;  4C8F A;  1V6C A;  2OR4 A;  4P4J A;  1TWA A;  4COG A;  5FD8 A;  5K99 A;  4JVO A;  2LTH A;  4NGT A;  3TLY A;  3U44 A;  3GTM A;  1YNN D;  2XEJ A;  1I3Q A;  1VI4 A;  4CDJ A;  3LR2 A;  1SMY D;  3GTG A;  3IWW A;  2LKM B;  2D0O A;  4X3R A;  2C6G A;  2R93 A;  4IIX A;  2EZB A;  3LR6 A;  2A6E D;  2O5J D;  3SJX A;  2K3Q A;  4P44 A;  2XEI A;  3TLC A;  4C6G A;  4MJX A;  3GTP A;  4JZ0 A;  4P45 A;  1KEE B;  3FEE A;  3SJE A;  3C8O A;  2C6P A;  2AQL A;  4OC3 A;  1Y1V A;  3TLZ A;  2N3E A;  2JA5 A;  2EK9 A;  1WCM A;  2K3N A;  1Q5X A;  2E28 A;  3EIF A;  2NVY A;  1K83 A;  1XF1 A;  1NBW A;  1KC7 A;  3S9M A;  4C8C A;  4TJX A;  2Y0N A;  1YNJ D;  4J0N A;  3KRV A;  3TLE A;  4MI1 A;  2AUM A;  3BI0 A;  3BHX A;  1T6P A;  3BI1 A;  4C5R A;  2XEF A;  5F1Y A;  2MQA A;  3TLG B;  1ZYM A;  3FED A;  3K9T A;  4V2R A;  3GTJ A;  3FF3 A;  2X0Q A;  3SJG A;  2HWG A;  4OC4 A;  2C5Q A;  3I6S A;  3TLG A;  2EZA A;  2R7Z A;  2FIP A;  2OOT A;  4C5S A;  5F5X A;  5JYB A;  1TWH A;  2C6C A;  1WVM A;  4C5U A;  3D7F A;  3T07 A;  3D7G A;  1T36 B;  4C8U A;  2R82 A;  3NZ4 A;  1ZRS A;  2DIK A;  2B0A A;  4OC5 A;  4CEI A;  2EZC A;  2A69 D;  2D0P A;  3TYX A;  3GTO A;  4C9R A;  4CEH A;  2HRO A;  1R9T A;  3GJZ A;  2LYI A;  4C9A A;  4CDK A;  1NXJ A;  2BE5 D;  2HI6 A;  1BXR B;  4CO9 A;  1CX8 A;  3FKI A;  4NGM A;  2R92 A;  5F09 A;  1C3O B;  4NGR A;  1VBH A;  5JVL A;  1ZL0 A;  3LR8 A;  3ICU A;  4OC0 A;  2YII A;  4TJV A;  1TWC A;  1GGO A;  1M6V B;  3T0T A;  4P4D A;  3GTK A;  5F9M A;  1A9X B;  1IW7 D;  5ELY A;  2FIO A;  4CEJ A;  2B63 A;  3I74 A;  3GTQ A;  2CIJ A;  4JYW A;  4EYS A;  2JA7 A;  2PVW A;  2CW0 D; 
#chains in the Genus database with same CATH homology
 1JDE A;  2FM4 A;  1ZYM A;  3T05 A;  2MP0 A;  3EZA A;  1GGO A;  3T07 A;  3T0T A;  2HRO A;  2HWG A;  3EZB A;  1EZA A;  2OLS A;  2X0S A;  2EZA A;  1VBG A;  2R82 A;  2E28 A;  2EZB A;  1VBH A;  1KBL A;  3EZE A;  2EZC A;  2DIK A;  1KC7 A;  5JVL A;  1EZB A;  1DIK A;  2HI6 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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