1ZYMA

Amino terminal domain of enzyme i from escherichia coli
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
247
structure length
247
Chain Sequence
SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ENZYME I
publication title The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
total genus 80
structure length 247
sequence length 247
chains with identical sequence B
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1996-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1zymA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1zymA01
2MP0A 5JVLA 2DIKA 3EZBA 3T05A 1VBHA 3EZAA 1GGOA 2OLSA 1EZBA 1VBGA 2HWGA 1KBLA 2X0SA 2EZAA 2HI6A 2EZCA 2E28A 2R82A 1JDEA 3EZEA 3T0TA 2HROA 1EZAA 2FM4A 2EZBA 1DIKA 3T07A 1ZYMA 1KC7A
chains in the Genus database with same CATH superfamily
1Z8LA 2NVYA 1TWAA 3TLZA 2JA5A 2AUNA 1NBWA 1EZBA 4TJXA 2A68D 3GTKA 1A9XB 1C3OB 1Y9ZA 4OC4A 2CIJA 4C8AA 1VI4A 1T6PA 3SJFA 5JVLA 3BI1A 4P4EA 2PCNA 2GP4A 1I3QA 4C86A 2JA7A 3LR2A 2OOTA 4OC5A 4IIXA 4CDKA 1YNND 2D0OA 2C6CA 2E2HA 4C8CA 4JYWA 4C84A 4INJA 4EYSA 4P4BA 3NZ4A 4C2MA 1J3LA 4TWEA 3T5MA 2B63A 4CQ5A 4LQGA 5F5XA 3TLYA 3GTOA 2FM4A 4OC0A 2A6ED 2N1DB 1KEEB 4MCQA 4QIWA 4P4DA 3TLEA 4CEJA 4C85A 2XEJA 4COGA 4OMEA 1TWCA 2R92A 2C5QA 1Y1WA 3TLGB 1KC7A 4CDJA 3D7HA 3K4IA 1C30B 4X3RA 4C9RA 3D7GA 2OLSA 4MCRA 3VTAA 2PVVA 4NGPA 3LRDA 2K3OA 2E2IA 3EZEA 5IB9A 3TLCA 4YN3A 1V6CA 4TJVA 2MP0A 3LR6A 2YU9A 2A69D 1ZL0A 1VBGA 1YNJD 3IIBA 3KRVA 2CW0D 1SMYD 4C8UA 3TYXA 2DIKA 4BAAA 1TWHA 2X0PA 3GTPA 3BHXA 3I6SA 2HWGA 3TLGA 3NOJA 1WVMA 4H1HA 3GTLA 1EZAA 4C9AA 3D7FA 2AUMA 1I50A 4OC1A 4C5RA 2Y0NA 3FF3A 2JBJA 3D7DA 4P45A 3U44A 1VBHA 1JDBC 3K9TA 3GTMA 2E28A 4J0NA 4NGRA 3GTGA 4C5UA 4CEHA 1IW7D 4P4JA 3I74A 3S9LA 2YIIA 5F1YA 2YJVA 2LPJA 1T36B 1SFOA 4CO9A 2EZAA 2HI6A 2N3EA 1R61A 4NGSA 3BXMA 4C8PA 2X0QA 2YJTA 2FIPA 2VUMA 4MJXA 2MX8A 3SR3A 2MX9A 3G23A 3EZAA 2AQLA 3EIFA 3LR8A 2R82A 3CQZA 1I6VD 3GTJA 3SJXA 3U4QA 3FKIA 1ZYMA 2FIOA 2PVWA 1TWGA 1CX8A 2EK9A 1CS0B 3U1BA 1Y2MA 5IR2A 4OC3A 3KASA 5ELYA 1ZYRD 2XEGA 3S9MA 3H0GA 1DE4C 2EZBA 2JA6A 5JYBA 4P4IA 3IWWA 3EZBA 1ZRSA 2C6PA 3C8OA 2K3QA 1K83A 2X0SA 5F9MA 2D0PA 1CE8B 1JDEA 5D29A 4KNGE 3TLBA 2XEIA 2X0OA 3T05A 4JVOA 3RBUA 4CZ1A 1NXJA 4CEIA 1KBLA 2C6GA 4NGQA 2LYIA 2LKMB 4M8DA 2F5JA 5IZ2A 4JZ0A 2O5JD 4V2QA 1DIKA 1Q5XA 4MI1A 2MQAA 1XF1A 4C99A 3GTQA 2LTHA 2K3NA 2LPIA 4V2RA 1GGOA 2R93A 3SJGA 2B0AA 4FBSA 2NVXA 4P44A 2EZCA 2EK8A 5F09A 2OR4A 3FECA 4C9EA 3SJEA 2VK9A 4E5SA 2BE5D 2A6HD 1R9TA 4C5SA 4COBA 4IIYA 1M6VB 4NGMA 2XEFA 4NGTA 5FD8A 4BABA 1HQMD 4C6GA 3BI0A 1WCMA 4C8TA 1W27A 4OC2A 3T0TA 2R7ZA 1Y1VA 3S9NA 4C9UA 1BXRB 4MCPA 1T6JA 4W9YA 4E94A 3TLAA 5K99A 4MCSA 3FEEA 4NGNA 4P4FA 3GJZA 2JBKA 4C8FA 2HROA 1TWFA 3ICUA 4C9VA 3T07A 3FEDA
chains in the Genus database with same CATH topology
2MP0A 5JVLA 2DIKA 3EZBA 3T05A 1VBHA 3EZAA 1GGOA 2OLSA 1EZBA 1VBGA 2HWGA 1KBLA 2X0SA 2EZAA 2HI6A 2EZCA 2E28A 2R82A 1JDEA 3EZEA 3T0TA 2HROA 1EZAA 2FM4A 2EZBA 1DIKA 3T07A 1ZYMA 1KC7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MP0 A;  5JVL A;  2DIK A;  3EZB A;  3T05 A;  1VBH A;  3EZA A;  1GGO A;  2OLS A;  1EZB A;  1VBG A;  2HWG A;  1KBL A;  2X0S A;  2EZA A;  2HI6 A;  2EZC A;  2E28 A;  2R82 A;  1JDE A;  3EZE A;  3T0T A;  2HRO A;  1EZA A;  2FM4 A;  2EZB A;  1DIK A;  3T07 A;  1ZYM A;  1KC7 A; 
#chains in the Genus database with same CATH topology
 1Z8L A;  2NVY A;  1TWA A;  3TLZ A;  2JA5 A;  2AUN A;  1NBW A;  1EZB A;  4TJX A;  2A68 D;  3GTK A;  1A9X B;  1C3O B;  1Y9Z A;  4OC4 A;  2CIJ A;  4C8A A;  1VI4 A;  1T6P A;  3SJF A;  5JVL A;  3BI1 A;  4P4E A;  2PCN A;  2GP4 A;  1I3Q A;  4C86 A;  2JA7 A;  3LR2 A;  2OOT A;  4OC5 A;  4IIX A;  4CDK A;  1YNN D;  2D0O A;  2C6C A;  2E2H A;  4C8C A;  4JYW A;  4C84 A;  4INJ A;  4EYS A;  4P4B A;  3NZ4 A;  4C2M A;  1J3L A;  4TWE A;  3T5M A;  2B63 A;  4CQ5 A;  4LQG A;  5F5X A;  3TLY A;  3GTO A;  2FM4 A;  4OC0 A;  2A6E D;  2N1D B;  1KEE B;  4MCQ A;  4QIW A;  4P4D A;  3TLE A;  4CEJ A;  4C85 A;  2XEJ A;  4COG A;  4OME A;  1TWC A;  2R92 A;  2C5Q A;  1Y1W A;  3TLG B;  1KC7 A;  4CDJ A;  3D7H A;  3K4I A;  1C30 B;  4X3R A;  4C9R A;  3D7G A;  2OLS A;  4MCR A;  3VTA A;  2PVV A;  4NGP A;  3LRD A;  2K3O A;  2E2I A;  3EZE A;  5IB9 A;  3TLC A;  4YN3 A;  1V6C A;  4TJV A;  2MP0 A;  3LR6 A;  2YU9 A;  2A69 D;  1ZL0 A;  1VBG A;  1YNJ D;  3IIB A;  3KRV A;  2CW0 D;  1SMY D;  4C8U A;  3TYX A;  2DIK A;  4BAA A;  1TWH A;  2X0P A;  3GTP A;  3BHX A;  3I6S A;  2HWG A;  3TLG A;  3NOJ A;  1WVM A;  4H1H A;  3GTL A;  1EZA A;  4C9A A;  3D7F A;  2AUM A;  1I50 A;  4OC1 A;  4C5R A;  2Y0N A;  3FF3 A;  2JBJ A;  3D7D A;  4P45 A;  3U44 A;  1VBH A;  1JDB C;  3K9T A;  3GTM A;  2E28 A;  4J0N A;  4NGR A;  3GTG A;  4C5U A;  4CEH A;  1IW7 D;  4P4J A;  3I74 A;  3S9L A;  2YII A;  5F1Y A;  2YJV A;  2LPJ A;  1T36 B;  1SFO A;  4CO9 A;  2EZA A;  2HI6 A;  2N3E A;  1R61 A;  4NGS A;  3BXM A;  4C8P A;  2X0Q A;  2YJT A;  2FIP A;  2VUM A;  4MJX A;  2MX8 A;  3SR3 A;  2MX9 A;  3G23 A;  3EZA A;  2AQL A;  3EIF A;  3LR8 A;  2R82 A;  3CQZ A;  1I6V D;  3GTJ A;  3SJX A;  3U4Q A;  3FKI A;  1ZYM A;  2FIO A;  2PVW A;  1TWG A;  1CX8 A;  2EK9 A;  1CS0 B;  3U1B A;  1Y2M A;  5IR2 A;  4OC3 A;  3KAS A;  5ELY A;  1ZYR D;  2XEG A;  3S9M A;  3H0G A;  1DE4 C;  2EZB A;  2JA6 A;  5JYB A;  4P4I A;  3IWW A;  3EZB A;  1ZRS A;  2C6P A;  3C8O A;  2K3Q A;  1K83 A;  2X0S A;  5F9M A;  2D0P A;  1CE8 B;  1JDE A;  5D29 A;  4KNG E;  3TLB A;  2XEI A;  2X0O A;  3T05 A;  4JVO A;  3RBU A;  4CZ1 A;  1NXJ A;  4CEI A;  1KBL A;  2C6G A;  4NGQ A;  2LYI A;  2LKM B;  4M8D A;  2F5J A;  5IZ2 A;  4JZ0 A;  2O5J D;  4V2Q A;  1DIK A;  1Q5X A;  4MI1 A;  2MQA A;  1XF1 A;  4C99 A;  3GTQ A;  2LTH A;  2K3N A;  2LPI A;  4V2R A;  1GGO A;  2R93 A;  3SJG A;  2B0A A;  4FBS A;  2NVX A;  4P44 A;  2EZC A;  2EK8 A;  5F09 A;  2OR4 A;  3FEC A;  4C9E A;  3SJE A;  2VK9 A;  4E5S A;  2BE5 D;  2A6H D;  1R9T A;  4C5S A;  4COB A;  4IIY A;  1M6V B;  4NGM A;  2XEF A;  4NGT A;  5FD8 A;  4BAB A;  1HQM D;  4C6G A;  3BI0 A;  1WCM A;  4C8T A;  1W27 A;  4OC2 A;  3T0T A;  2R7Z A;  1Y1V A;  3S9N A;  4C9U A;  1BXR B;  4MCP A;  1T6J A;  4W9Y A;  4E94 A;  3TLA A;  5K99 A;  4MCS A;  3FEE A;  4NGN A;  4P4F A;  3GJZ A;  2JBK A;  4C8F A;  2HRO A;  1TWF A;  3ICU A;  4C9V A;  3T07 A;  3FED A; 
#chains in the Genus database with same CATH homology
 2MP0 A;  5JVL A;  2DIK A;  3EZB A;  3T05 A;  1VBH A;  3EZA A;  1GGO A;  2OLS A;  1EZB A;  1VBG A;  2HWG A;  1KBL A;  2X0S A;  2EZA A;  2HI6 A;  2EZC A;  2E28 A;  2R82 A;  1JDE A;  3EZE A;  3T0T A;  2HRO A;  1EZA A;  2FM4 A;  2EZB A;  1DIK A;  3T07 A;  1ZYM A;  1KC7 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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