1ZYMA

Amino terminal domain of enzyme i from escherichia coli
Total Genus 80
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
247
structure length
247
Chain Sequence
SGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRAVQEQVASE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Phosphotransferase
molecule keywords ENZYME I
total genus 80
structure length 247
sequence length 247
chains with identical sequence B
ec nomenclature ec 2.7.3.9: Phosphoenolpyruvate--protein phosphotransferase.
pdb deposition date 1996-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00391 PEP-utilizers PEP-utilising enzyme, mobile domain
A PF05524 PEP-utilisers_N PEP-utilising enzyme, N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.10 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 PtsI, HPr-binding domain 1zymA02
3.50.30.10 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Phosphohistidine domain 1zymA01
2HWGA 1DIKA 1GGOA 3T07A 1EZAA 2X0SA 2HI6A 3T05A 3EZBA 2R82A 3T0TA 2OLSA 1KBLA 2E28A 2FM4A 2EZBA 5JVLA 3EZEA 1VBGA 1EZBA 1ZYMA 1JDEA 1KC7A 2MP0A 2EZAA 3EZAA 2DIKA 2HROA 1VBHA 2EZCA
chains in the Genus database with same CATH superfamily
3GTPA 1SMYD 1DE4C 3VTAA 3BI0A 2BE5D 3D7FA 4YN3A 3U4QA 2A6HD 5FD8A 3T07A 3U44A 2O5JD 1TWFA 2A6ED 2K3QA 5F09A 4P45A 1Y1VA 3LRDA 3BI1A 4C84A 2X0SA 4EYSA 3EZBA 1I3QA 3T0TA 4BAAA 3SR3A 4E5SA 1T6JA 1NXJA 3D7GA 2N1DB 4C8TA 2JA5A 3IIBA 1TWCA 4BABA 1BXRB 2C6PA 3KRVA 4C85A 2JA6A 2YU9A 1CS0B 3EZEA 4CDKA 2MX9A 1VBGA 4P4IA 3U1BA 3GTKA 1EZBA 2B0AA 4CQ5A 1ZYMA 3GTMA 1NBWA 3C8OA 4MCQA 2F5JA 4IIYA 4CEHA 1ZRSA 2R92A 3GTGA 2OOTA 4C86A 2A69D 3S9NA 4C8FA 1JDBC 4NGNA 2HROA 4C8PA 4NGSA 2EZCA 5F1YA 1TWHA 2R93A 4NGRA 4JZ0A 1GGOA 3I74A 4V2RA 4NGQA 1W27A 1ZYRD 4X3RA 4CZ1A 1EZAA 2YIIA 4TWEA 3SJEA 3KASA 4MCRA 3RBUA 2HI6A 4NGTA 5D29A 4C99A 4C5UA 4C5RA 4C5SA 2PVWA 1Y2MA 3T5MA 2CIJA 2OLSA 3TLGB 2C5QA 3TLZA 2Y0NA 1I6VD 3K9TA 4P4EA 2E2IA 4MCPA 1Y1WA 4INJA 4TJXA 4NGPA 3ICUA 2LPJA 3I6SA 2NVYA 3S9MA 4C9EA 1KC7A 1M6VB 1TWAA 4P44A 1WVMA 4J0NA 5F9MA 1KEEB 2X0QA 3EZAA 1Y9ZA 5IR2A 4COGA 3GTOA 2CW0D 2JBJA 4M8DA 1YNND 3G23A 3TLBA 4P4BA 1A9XB 2PCNA 1T6PA 1VI4A 4LQGA 4C6GA 4P4DA 3TLEA 5K99A 2VUMA 2C6CA 4CEIA 4OC1A 4CEJA 4CO9A 3SJFA 2R82A 3D7DA 4CDJA 2D0OA 2MQAA 1ZL0A 1SFOA 1R9TA 1YNJD 1K83A 2E2HA 1V6CA 1IW7D 2E28A 1Q5XA 2XEGA 4OC4A 3TLAA 5ELYA 4C9VA 4FBSA 5IB9A 3CQZA 1TWGA 4JYWA 3FEEA 3TLGA 4C8UA 1JDEA 3LR8A 2AUMA 2MP0A 2EZAA 2X0PA 3H0GA 2LTHA 2MX8A 2X0OA 1C30B 2JBKA 2YJTA 4P4FA 1WCMA 2N3EA 4C8CA 2AUNA 2EK9A 3IWWA 4C8AA 2DIKA 3TYXA 1XF1A 2K3NA 2A68D 2XEIA 4MJXA 4P4JA 4E94A 2JA7A 2HWGA 4TJVA 4C2MA 5IZ2A 1DIKA 2D0PA 2EK8A 4C9UA 5JVLA 2LKMB 3S9LA 2AQLA 2FIOA 4JVOA 4KNGE 4C9AA 4OC0A 3FKIA 4QIWA 3D7HA 1I50A 2NVXA 1CX8A 2XEJA 3FF3A 1CE8B 3T05A 2FIPA 2B63A 1C3OB 2YJVA 4MI1A 4OC3A 1T36B 5JYBA 1KBLA 4OC5A 3TLYA 4NGMA 1J3LA 2XEFA 4OMEA 2R7ZA 2FM4A 2EZBA 2OR4A 3EIFA 3GJZA 4MCSA 4C9RA 2LYIA 3K4IA 2C6GA 3LR6A 4V2QA 1HQMD 3NOJA 3SJGA 3GTQA 2K3OA 3LR2A 3GTLA 4W9YA 4H1HA 5F5XA 2LPIA 4COBA 2VK9A 3GTJA 3FEDA 3BXMA 3FECA 4OC2A 3SJXA 2PVVA 1R61A 4IIXA 2GP4A 3BHXA 1Z8LA 1VBHA 3TLCA 3NZ4A
chains in the Genus database with same CATH topology
2HWGA 1DIKA 1GGOA 3T07A 1EZAA 2X0SA 2HI6A 3T05A 3EZBA 2R82A 3T0TA 2OLSA 1KBLA 2E28A 2FM4A 2EZBA 5JVLA 3EZEA 1VBGA 1EZBA 1ZYMA 1JDEA 1KC7A 2MP0A 2EZAA 3EZAA 2DIKA 2HROA 1VBHA 2EZCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HWG A;  1DIK A;  1GGO A;  3T07 A;  1EZA A;  2X0S A;  2HI6 A;  3T05 A;  3EZB A;  2R82 A;  3T0T A;  2OLS A;  1KBL A;  2E28 A;  2FM4 A;  2EZB A;  5JVL A;  3EZE A;  1VBG A;  1EZB A;  1ZYM A;  1JDE A;  1KC7 A;  2MP0 A;  2EZA A;  3EZA A;  2DIK A;  2HRO A;  1VBH A;  2EZC A; 
#chains in the Genus database with same CATH topology
 3GTP A;  1SMY D;  1DE4 C;  3VTA A;  3BI0 A;  2BE5 D;  3D7F A;  4YN3 A;  3U4Q A;  2A6H D;  5FD8 A;  3T07 A;  3U44 A;  2O5J D;  1TWF A;  2A6E D;  2K3Q A;  5F09 A;  4P45 A;  1Y1V A;  3LRD A;  3BI1 A;  4C84 A;  2X0S A;  4EYS A;  3EZB A;  1I3Q A;  3T0T A;  4BAA A;  3SR3 A;  4E5S A;  1T6J A;  1NXJ A;  3D7G A;  2N1D B;  4C8T A;  2JA5 A;  3IIB A;  1TWC A;  4BAB A;  1BXR B;  2C6P A;  3KRV A;  4C85 A;  2JA6 A;  2YU9 A;  1CS0 B;  3EZE A;  4CDK A;  2MX9 A;  1VBG A;  4P4I A;  3U1B A;  3GTK A;  1EZB A;  2B0A A;  4CQ5 A;  1ZYM A;  3GTM A;  1NBW A;  3C8O A;  4MCQ A;  2F5J A;  4IIY A;  4CEH A;  1ZRS A;  2R92 A;  3GTG A;  2OOT A;  4C86 A;  2A69 D;  3S9N A;  4C8F A;  1JDB C;  4NGN A;  2HRO A;  4C8P A;  4NGS A;  2EZC A;  5F1Y A;  1TWH A;  2R93 A;  4NGR A;  4JZ0 A;  1GGO A;  3I74 A;  4V2R A;  4NGQ A;  1W27 A;  1ZYR D;  4X3R A;  4CZ1 A;  1EZA A;  2YII A;  4TWE A;  3SJE A;  3KAS A;  4MCR A;  3RBU A;  2HI6 A;  4NGT A;  5D29 A;  4C99 A;  4C5U A;  4C5R A;  4C5S A;  2PVW A;  1Y2M A;  3T5M A;  2CIJ A;  2OLS A;  3TLG B;  2C5Q A;  3TLZ A;  2Y0N A;  1I6V D;  3K9T A;  4P4E A;  2E2I A;  4MCP A;  1Y1W A;  4INJ A;  4TJX A;  4NGP A;  3ICU A;  2LPJ A;  3I6S A;  2NVY A;  3S9M A;  4C9E A;  1KC7 A;  1M6V B;  1TWA A;  4P44 A;  1WVM A;  4J0N A;  5F9M A;  1KEE B;  2X0Q A;  3EZA A;  1Y9Z A;  5IR2 A;  4COG A;  3GTO A;  2CW0 D;  2JBJ A;  4M8D A;  1YNN D;  3G23 A;  3TLB A;  4P4B A;  1A9X B;  2PCN A;  1T6P A;  1VI4 A;  4LQG A;  4C6G A;  4P4D A;  3TLE A;  5K99 A;  2VUM A;  2C6C A;  4CEI A;  4OC1 A;  4CEJ A;  4CO9 A;  3SJF A;  2R82 A;  3D7D A;  4CDJ A;  2D0O A;  2MQA A;  1ZL0 A;  1SFO A;  1R9T A;  1YNJ D;  1K83 A;  2E2H A;  1V6C A;  1IW7 D;  2E28 A;  1Q5X A;  2XEG A;  4OC4 A;  3TLA A;  5ELY A;  4C9V A;  4FBS A;  5IB9 A;  3CQZ A;  1TWG A;  4JYW A;  3FEE A;  3TLG A;  4C8U A;  1JDE A;  3LR8 A;  2AUM A;  2MP0 A;  2EZA A;  2X0P A;  3H0G A;  2LTH A;  2MX8 A;  2X0O A;  1C30 B;  2JBK A;  2YJT A;  4P4F A;  1WCM A;  2N3E A;  4C8C A;  2AUN A;  2EK9 A;  3IWW A;  4C8A A;  2DIK A;  3TYX A;  1XF1 A;  2K3N A;  2A68 D;  2XEI A;  4MJX A;  4P4J A;  4E94 A;  2JA7 A;  2HWG A;  4TJV A;  4C2M A;  5IZ2 A;  1DIK A;  2D0P A;  2EK8 A;  4C9U A;  5JVL A;  2LKM B;  3S9L A;  2AQL A;  2FIO A;  4JVO A;  4KNG E;  4C9A A;  4OC0 A;  3FKI A;  4QIW A;  3D7H A;  1I50 A;  2NVX A;  1CX8 A;  2XEJ A;  3FF3 A;  1CE8 B;  3T05 A;  2FIP A;  2B63 A;  1C3O B;  2YJV A;  4MI1 A;  4OC3 A;  1T36 B;  5JYB A;  1KBL A;  4OC5 A;  3TLY A;  4NGM A;  1J3L A;  2XEF A;  4OME A;  2R7Z A;  2FM4 A;  2EZB A;  2OR4 A;  3EIF A;  3GJZ A;  4MCS A;  4C9R A;  2LYI A;  3K4I A;  2C6G A;  3LR6 A;  4V2Q A;  1HQM D;  3NOJ A;  3SJG A;  3GTQ A;  2K3O A;  3LR2 A;  3GTL A;  4W9Y A;  4H1H A;  5F5X A;  2LPI A;  4COB A;  2VK9 A;  3GTJ A;  3FED A;  3BXM A;  3FEC A;  4OC2 A;  3SJX A;  2PVV A;  1R61 A;  4IIX A;  2GP4 A;  3BHX A;  1Z8L A;  1VBH A;  3TLC A;  3NZ4 A; 
#chains in the Genus database with same CATH homology
 2HWG A;  1DIK A;  1GGO A;  3T07 A;  1EZA A;  2X0S A;  2HI6 A;  3T05 A;  3EZB A;  2R82 A;  3T0T A;  2OLS A;  1KBL A;  2E28 A;  2FM4 A;  2EZB A;  5JVL A;  3EZE A;  1VBG A;  1EZB A;  1ZYM A;  1JDE A;  1KC7 A;  2MP0 A;  2EZA A;  3EZA A;  2DIK A;  2HRO A;  1VBH A;  2EZC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...