1AENA

Specificity of ligand binding to a buried polar cavity at the active site of cytochrome c peroxidase (2-amino-5-methylthiazole)
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
291
structure length
291
Chain Sequence
LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPGGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLEDGITFPKDAPSPFIFKTLEEQGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Saccharomyces cerevisiae
molecule keywords CYTOCHROME C PEROXIDASE
total genus 96
structure length 291
sequence length 291
ec nomenclature ec 1.11.1.5: Cytochrome-c peroxidase.
pdb deposition date 1997-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00141 peroxidase Peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.420.10 Mainly Alpha Orthogonal Bundle Peroxidase; domain 2 Peroxidase, domain 2 1aenA02
1.10.520.10 Mainly Alpha Orthogonal Bundle Peroxidase; domain 1 Peroxidase; domain 1 1aenA01
1CCKA 1CPFA 1U74A 1B82A 1KRJA 5KSKA 3VLIA 5CIGA 1AC8A 3WNUA 2N18A 4BLNA 1AEHA 1SDQA 5CIBA 4NVLA 1GWTA 5CIDA 3VLJA 1LGAA 4JMTA 4NVIB 5CICA 4CCXA 2EUOA 1CCEA 2B12A 1RYCA 4FCSA 4CZOA 3UT2A 3CCXA 1U75A 5SYHA 3M2FA 3ATJA 5JHZA 1MNPA 2RBUX 1DJ1A 1AEEA 5SYVA 3M2IA 4NVCA 1YZPA 5SYIA 4JMZA 1GZAA 1BEMA 2RC2X 5KQ2A 4G05A 1W4YA 1GWOA 2XI6A 3VLHA 2X08A 4XV5A 5SW5A 1ZBZA 3M8MA 2RBZX 2JTIA 2AS6A 4NVBA 1CCIA 4BLXA 3M2EA 1GX2A 1SOGA 2XJ6A 2AS1A 1ARUA 2RBWX 7CCPA 1CMPA 2BCNA 1AEVA 4JQJA 2E3BA 1U2LA 5AMMA 5CIFA 5SYJA 5SYXA 1S6VA 1MKQA 1BEKA 3FMUA 3RIVA 3M2BA 3ZCYA 1H3JA 4BLKA 1DSOA 4NVJB 5EJXA 2GHDX 5SX0A 1H5FA 2CYPA 1W4WA 1H5GA 2YLJA 2EUQA 5FNBA 1LY9A 1CMQA 1STQA 2ATJA 4JPTA 4BM3A 1Z53A 5L05A 1MN2A 1AEMA 5L86A 2V2EA 2EUUA 1LY8A 5SX0B 2X07A 1CCAA 2XIFA 2VCFX 5CIEA 4CZQA 1C8IA 1EBEA 1QPAA 1U2KA 4BLZA 3M29A 5SYUA 4BLYA 5SW4A 4JMBA 4NVFA 5ABQA 2XJ8A 2EUSA 1HSRA 3WXOA 2B11A 2EUTA 4JMWA 1OAFA 1H5HA 1H5IA 1SCHA 5ALAA 1BVAA 4BM0A 1BEQA 2GHEX 1H5AA 2GB8A 4JM9A 1JDRA 2V23A 5SW6A 5KSFA 1AEGA 1ARXA 3M27A 1PA2A 1H5CA 2XJ5A 1CMTA 5JHXA 2CL4X 4FCNA 4PAEA 3CCPA 2Y5AA 4NVEA 2RBYX 1A2FA 4A5GA 6ATJA 5ABNA 5KQ0A 1QO4A 3Q3UA 1FHFA 1CYFA 4XV8A 5JQRA 4C51A 5KQ3A 4JQKA 1MK8A 1CCBA 4BM4A 2VCNA 1S73A 2RBTX 1CMUA 4CVJA 1CCCA 5ABOA 1AEDA 2WD4A 2GHKX 4NVGB 4GEDA 3VLKA 1APXA 4BM1A 1SBMA 1ZBYA 2GHHX 5SYWA 2RC0X 1A2GA 1IYNA 5FNEA 2IA8A 2CEPA 5SXXA 2GGNX 1ARWA 1KXMA 1H58A 1JCIA 3FM6A 2VCSA 3M23A 2XILA 4JMVA 1YYGA 3M25A 2AQDA 1MN1A 1ITKA 5SX7A 5SYKA 5SX1A 1AETA 5SXTA 1AEBA 3E2NA 5CIHA 3E2OA 1AC4A 5KQ6A 3M2DA 2B10A 1ML2A 1DCCA 5CCPA 1MKRA 1AEKA 4FDQA 2EURA 4CZRA 2Y6BA 5SXQA 1KZMA 2E39A 1LYKA 4P4QA 5L02A 1AA4A 1AENA 1BESA 1BEPA 1DJ5A 1B85A 1AEQA 1H57A 3ZCHA 2RC1X 1BJ9A 3VLMA 5JPRA 1H55A 1OAGA 3M2GA 4JPLA 2XIHA 5KQKA 2PCCA 1YZRA 2Y6AA 1CPGA 1H5KA 4JQNA 1V0HX 2E3AA 7ATJA 3M2CA 1LYCA 3VLLA 5SXRA 5SX6A 1H5EA 5D6MA 2AS3A 1ARVA 1LLPA 1BEJA 4CUOA 4CVIA 5KQIA 6CCPA 4XV7A 3FKGA 2BOQA 4NVDA 4XVAA 4CZPA 2CCDA 1KXNA 4NVMB 3M26A 4XV6A 3ZCGA 1AEOA 1ARYA 5KQHA 4CCPA 2AS4A 1U2JA 1DSEA 3R98A 4JMAA 1HCHA 5SX3A 1UB2A 1GWUA 5SXSA 1YYDA 3RRWA 4A78A 5SYYA 2B0ZA 4A6ZA 1CPEA 4JN0A 1GW2A 1AEJA 4FEFA 1QGJA 3M2HA 5CJHA 5SYLA 3EXBA 4USCA 1CPDA 4NVAA 3UW8A 1ARPA 5JHYA 1BGPA 1H5LA 3FM4A 3X16A 1H5DA 1CCPA 4NVKB 1CCLA 4NVNB 1DSPA 3M5QA 2VKAA 3RIWA 5SXWA 1B80A 2PCBA 2VNXX 4A71A 2ICVA 1GZBA 4A7MA 4BM2A 4JM5A 2VO2X 3HDLA 1KOKA 2RBVX 1H5MA 2EUPA 5SX2A 1CK6A 1CCJA 2YCGA 2CCPA 2VNZX 1AESA 3M28A 3FJWA 3M2AA 4JB4A 4JM8A 5AOGA 4NVOB 1H5JA 4NFGA 4OQ7A 2EUNA 1AEFA 4JMSA 2GHCX 4C50A 1CCGA 4ATJA 2ANZA 2W23A 1DS4A 5AL9A 1DSGA 4BLLA 1SJ2A 2RBXX 1ATJA 3FM1A 4JM6A 4JPUA 2CCAA 4CZNA 2AS2A 3R99A 5EJTA 1AEUA 4NVHB 4JQMA 4XV4A
chains in the Genus database with same CATH superfamily
1CCKA 1CPFA 1U74A 1B82A 1KRJA 5KSKA 3VLIA 5CIGA 1AC8A 3WNUA 2N18A 4BLNA 1AEHA 1SDQA 5CIBA 4NVLA 1GWTA 5CIDA 3VLJA 1LGAA 4JMTA 4NVIB 5CICA 4CCXA 2EUOA 1CCEA 2B12A 1RYCA 4FCSA 4CZOA 3UT2A 3CCXA 1U75A 5SYHA 3M2FA 3ATJA 5JHZA 1MNPA 4H7AA 2RBUX 1DJ1A 1AEEA 4GKFA 2ZCAA 5SYVA 3M2IA 4NVCA 1YZPA 5SYIA 4JMZA 1GZAA 1BEMA 2RC2X 5KQ2A 4G05A 1W4YA 1GWOA 2XI6A 3VLHA 2X08A 4XV5A 5SW5A 1ZBZA 3M8MA 2RBZX 2JTIA 2AS6A 4NVBA 1CCIA 4BLXA 3M2EA 1GX2A 1SOGA 2XJ6A 2AS1A 1ARUA 2RBWX 7CCPA 1CMPA 2BCNA 1AEVA 4JQJA 2E3BA 1U2LA 5AMMA 5CIFA 5SYJA 5SYXA 1S6VA 1MKQA 1BEKA 3FMUA 3RIVA 3M2BA 3ZCYA 1H3JA 4BLKA 1DSOA 4NVJB 5EJXA 2GHDX 5SX0A 1H5FA 2CYPA 1W4WA 1H5GA 2YLJA 2EUQA 5FNBA 1LY9A 1CMQA 1STQA 2ATJA 4JPTA 4BM3A 1Z53A 5L05A 1MN2A 1AEMA 5L86A 2V2EA 2EUUA 1LY8A 5SX0B 2X07A 1CCAA 2XIFA 2BO5A 2VCFX 5CIEA 4CZQA 1C8IA 1EBEA 1QPAA 1U2KA 4BLZA 3M29A 5SYUA 4BLYA 5SW4A 4JMBA 4NVFA 5ABQA 2XJ8A 2EUSA 1HSRA 3WXOA 2B11A 2ZOPA 2EUTA 4JMWA 1OAFA 1H5HA 1H5IA 1SCHA 5ALAA 1BVAA 4BM0A 1BEQA 2GHEX 1H5AA 2GB8A 4JM9A 1JDRA 2V23A 5SW6A 5KSFA 1AEGA 1ARXA 3M27A 1PA2A 1H5CA 2XJ5A 4H79A 1CMTA 5JHXA 2CL4X 4FCNA 4JZAA 4PAEA 3CCPA 2Y5AA 4NVEA 2RBYX 1A2FA 4A5GA 6ATJA 5ABNA 5KQ0A 1QO4A 3Q3UA 1FHFA 1CYFA 4XV8A 5JQRA 4C51A 5KQ3A 4JQKA 1MK8A 1CCBA 4BM4A 2VCNA 1S73A 2RBTX 5CD4J 1CMUA 4CVJA 1CCCA 5ABOA 1AEDA 2WD4A 2GHKX 4NVGB 4GEDA 3VLKA 1APXA 4BM1A 1SBMA 1ZBYA 2GHHX 5SYWA 2RC0X 1A2GA 1IYNA 5FNEA 2IA8A 2CEPA 5SXXA 2GGNX 1ARWA 1KXMA 1H58A 1JCIA 3FM6A 2VCSA 3M23A 2XILA 4JMVA 1YYGA 3M25A 2AQDA 1MN1A 1ITKA 5SX7A 5SYKA 5H9EB 5SX1A 1AETA 5SXTA 1AEBA 5H9FB 3E2NA 5CIHA 3E2OA 1AC4A 5KQ6A 1ABVA 3M2DA 2B10A 4QYZB 1ML2A 2A7UB 1DCCA 5CCPA 1MKRA 1AEKA 4FDQA 2EURA 4CZRA 2Y6BA 5SXQA 1KZMA 2E39A 1LYKA 4P4QA 5L02A 1AA4A 1AENA 1BESA 1BEPA 1DJ5A 1B85A 3X1LF 1AEQA 1H57A 3ZCHA 2RC1X 1BJ9A 3VLMA 5JPRA 1H55A 1OAGA 3M2GA 4JPLA 2XIHA 5KQKA 2PCCA 1YZRA 2Y6AA 1CPGA 1H5KA 4JQNA 1V0HX 2E3AA 7ATJA 3M2CA 1LYCA 3VLLA 5SXRA 5SX6A 1H5EA 5D6MA 2AS3A 2JMXA 1ARVA 1LLPA 1BEJA 4CUOA 4CVIA 5KQIA 6CCPA 4XV7A 3FKGA 2BOQA 4NVDA 4XVAA 4CZPA 2CCDA 1KXNA 4NVMB 3M26A 4XV6A 3ZCGA 1AEOA 1ARYA 5KQHA 4CCPA 2AS4A 1U2JA 1DSEA 3R98A 4JMAA 1HCHA 5SX3A 1UB2A 1GWUA 5SXSA 1YYDA 3RRWA 4A78A 5SYYA 2B0ZA 4A6ZA 1CPEA 4JN0A 1GW2A 1AEJA 4FEFA 1QGJA 3M2HA 5CJHA 5SYLA 3EXBA 4USCA 1CPDA 4NVAA 3UW8A 1ARPA 5JHYA 1BGPA 1H5LA 3FM4A 3X16A 1H5DA 1CCPA 4NVKB 1CCLA 4NVNB 1DSPA 3M5QA 2VKAA 3RIWA 5SXWA 1B80A 2PCBA 2VNXX 4A71A 2ICVA 1GZBA 4A7MA 4BM2A 4JM5A 2VO2X 3HDLA 1KOKA 2RBVX 1H5MA 2EUPA 5SX2A 1CK6A 1CCJA 2YCGA 2CCPA 2VNZX 1AESA 3M28A 3FJWA 3M2AA 4JB4A 4JM8A 3WA8A 5AOGA 4NVOB 1H5JA 4NFGA 4OQ7A 2EUNA 1AEFA 2OEBA 4JMSA 2GHCX 4C50A 1CCGA 4ATJA 2ANZA 2W23A 1DS4A 5AL9A 2WSSS 1DSGA 4BLLA 1SJ2A 2RBXX 1ATJA 3FM1A 4JM6A 4JPUA 4U7UB 2CCAA 4CZNA 2AS2A 3R99A 5EJTA 1AEUA 4NVHB 4JQMA 4XV4A
chains in the Genus database with same CATH topology
1CCKA 1CPFA 1U74A 1B82A 1KRJA 5KSKA 3VLIA 5CIGA 1AC8A 3WNUA 2N18A 4BLNA 1AEHA 1SDQA 5CIBA 4NVLA 1GWTA 5CIDA 3VLJA 1LGAA 4JMTA 4NVIB 5CICA 4CCXA 2EUOA 1CCEA 2B12A 1RYCA 4FCSA 4CZOA 3UT2A 3CCXA 1U75A 5SYHA 3M2FA 3ATJA 5JHZA 1MNPA 4H7AA 2RBUX 1DJ1A 1AEEA 2ZCAA 5SYVA 3M2IA 4NVCA 1YZPA 5SYIA 4JMZA 1GZAA 1BEMA 2RC2X 5KQ2A 4G05A 1W4YA 1GWOA 2XI6A 3VLHA 2X08A 4XV5A 5SW5A 1ZBZA 3M8MA 2RBZX 2JTIA 2AS6A 4NVBA 1CCIA 4BLXA 3M2EA 1GX2A 1SOGA 2XJ6A 2AS1A 1ARUA 2RBWX 7CCPA 1CMPA 2BCNA 1AEVA 4JQJA 2E3BA 1U2LA 5AMMA 5CIFA 5SYJA 5SYXA 1S6VA 1MKQA 1BEKA 3FMUA 3RIVA 3M2BA 3ZCYA 1H3JA 4BLKA 1DSOA 4NVJB 5EJXA 2GHDX 5SX0A 1H5FA 2CYPA 1W4WA 1H5GA 2YLJA 2EUQA 5FNBA 1LY9A 1CMQA 1STQA 2ATJA 4JPTA 4BM3A 1Z53A 5L05A 1MN2A 1AEMA 5L86A 2V2EA 2EUUA 1LY8A 5SX0B 2X07A 1CCAA 2XIFA 2VCFX 5CIEA 4CZQA 1C8IA 1EBEA 1QPAA 1U2KA 4BLZA 3M29A 5SYUA 4BLYA 5SW4A 4JMBA 4NVFA 5ABQA 2XJ8A 2EUSA 1HSRA 3WXOA 2B11A 2EUTA 4JMWA 1OAFA 1H5HA 1H5IA 1SCHA 5ALAA 1BVAA 4BM0A 1BEQA 2GHEX 1H5AA 2GB8A 4JM9A 1JDRA 2V23A 5SW6A 5KSFA 1AEGA 1ARXA 3M27A 1PA2A 1H5CA 2XJ5A 4H79A 1CMTA 5JHXA 2CL4X 4FCNA 4JZAA 4PAEA 3CCPA 2Y5AA 4NVEA 2RBYX 1A2FA 4A5GA 6ATJA 5ABNA 5KQ0A 1QO4A 3Q3UA 1FHFA 1CYFA 4XV8A 5JQRA 4C51A 5KQ3A 4JQKA 1MK8A 1CCBA 4BM4A 2VCNA 1S73A 2RBTX 5CD4J 1CMUA 4CVJA 1CCCA 5ABOA 1AEDA 2WD4A 2GHKX 4NVGB 4GEDA 3VLKA 1APXA 4BM1A 1SBMA 1ZBYA 2GHHX 5SYWA 2RC0X 1A2GA 1IYNA 5FNEA 2IA8A 2CEPA 5SXXA 2GGNX 1ARWA 1KXMA 1H58A 1JCIA 3FM6A 2VCSA 3M23A 2XILA 4JMVA 1YYGA 3M25A 2AQDA 1MN1A 1ITKA 5SX7A 5SYKA 5H9EB 5SX1A 1AETA 5SXTA 1AEBA 5H9FB 3E2NA 5CIHA 3E2OA 1AC4A 5KQ6A 3M2DA 2B10A 4QYZB 1ML2A 1DCCA 5CCPA 1MKRA 1AEKA 4FDQA 2EURA 4CZRA 2Y6BA 5SXQA 1KZMA 2E39A 1LYKA 4P4QA 5L02A 1AA4A 1AENA 1BESA 1BEPA 1DJ5A 1B85A 1AEQA 1H57A 3ZCHA 2RC1X 1BJ9A 3VLMA 5JPRA 1H55A 1OAGA 3M2GA 4JPLA 2XIHA 5KQKA 2PCCA 1YZRA 2Y6AA 1CPGA 1H5KA 4JQNA 1V0HX 2E3AA 7ATJA 3M2CA 1LYCA 3VLLA 5SXRA 5SX6A 1H5EA 5D6MA 2AS3A 1ARVA 1LLPA 1BEJA 4CUOA 4CVIA 5KQIA 6CCPA 4XV7A 3FKGA 2BOQA 4NVDA 4XVAA 4CZPA 2CCDA 1KXNA 4NVMB 3M26A 4XV6A 3ZCGA 1AEOA 1ARYA 5KQHA 4CCPA 2AS4A 1U2JA 1DSEA 3R98A 4JMAA 1HCHA 5SX3A 1UB2A 1GWUA 5SXSA 1YYDA 3RRWA 4A78A 5SYYA 2B0ZA 4A6ZA 1CPEA 4JN0A 1GW2A 1AEJA 4FEFA 1QGJA 3M2HA 5CJHA 5SYLA 3EXBA 4USCA 1CPDA 4NVAA 3UW8A 1ARPA 5JHYA 1BGPA 1H5LA 3FM4A 3X16A 1H5DA 1CCPA 4NVKB 1CCLA 4NVNB 1DSPA 3M5QA 2VKAA 3RIWA 5SXWA 1B80A 2PCBA 2VNXX 4A71A 2ICVA 1GZBA 4A7MA 4BM2A 4JM5A 2VO2X 3HDLA 1KOKA 2RBVX 1H5MA 2EUPA 5SX2A 1CK6A 1CCJA 2YCGA 2CCPA 2VNZX 1AESA 3M28A 3FJWA 3M2AA 4JB4A 4JM8A 3WA8A 5AOGA 4NVOB 1H5JA 4NFGA 4OQ7A 2EUNA 1AEFA 4JMSA 2GHCX 4C50A 1CCGA 4ATJA 2ANZA 2W23A 1DS4A 5AL9A 1DSGA 4BLLA 1SJ2A 2RBXX 1ATJA 3FM1A 4JM6A 4JPUA 4U7UB 2CCAA 4CZNA 2AS2A 3R99A 5EJTA 1AEUA 4NVHB 4JQMA 4XV4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CCK A;  1CPF A;  1U74 A;  1B82 A;  1KRJ A;  5KSK A;  3VLI A;  5CIG A;  1AC8 A;  3WNU A;  2N18 A;  4BLN A;  1AEH A;  1SDQ A;  5CIB A;  4NVL A;  1GWT A;  5CID A;  3VLJ A;  1LGA A;  4JMT A;  4NVI B;  5CIC A;  4CCX A;  2EUO A;  1CCE A;  2B12 A;  1RYC A;  4FCS A;  4CZO A;  3UT2 A;  3CCX A;  1U75 A;  5SYH A;  3M2F A;  3ATJ A;  5JHZ A;  1MNP A;  2RBU X;  1DJ1 A;  1AEE A;  5SYV A;  3M2I A;  4NVC A;  1YZP A;  5SYI A;  4JMZ A;  1GZA A;  1BEM A;  2RC2 X;  5KQ2 A;  4G05 A;  1W4Y A;  1GWO A;  2XI6 A;  3VLH A;  2X08 A;  4XV5 A;  5SW5 A;  1ZBZ A;  3M8M A;  2RBZ X;  2JTI A;  2AS6 A;  4NVB A;  1CCI A;  4BLX A;  3M2E A;  1GX2 A;  1SOG A;  2XJ6 A;  2AS1 A;  1ARU A;  2RBW X;  7CCP A;  1CMP A;  2BCN A;  1AEV A;  4JQJ A;  2E3B A;  1U2L A;  5AMM A;  5CIF A;  5SYJ A;  5SYX A;  1S6V A;  1MKQ A;  1BEK A;  3FMU A;  3RIV A;  3M2B A;  3ZCY A;  1H3J A;  4BLK A;  1DSO A;  4NVJ B;  5EJX A;  2GHD X;  5SX0 A;  1H5F A;  2CYP A;  1W4W A;  1H5G A;  2YLJ A;  2EUQ A;  5FNB A;  1LY9 A;  1CMQ A;  1STQ A;  2ATJ A;  4JPT A;  4BM3 A;  1Z53 A;  5L05 A;  1MN2 A;  1AEM A;  5L86 A;  2V2E A;  2EUU A;  1LY8 A;  5SX0 B;  2X07 A;  1CCA A;  2XIF A;  2VCF X;  5CIE A;  4CZQ A;  1C8I A;  1EBE A;  1QPA A;  1U2K A;  4BLZ A;  3M29 A;  5SYU A;  4BLY A;  5SW4 A;  4JMB A;  4NVF A;  5ABQ A;  2XJ8 A;  2EUS A;  1HSR A;  3WXO A;  2B11 A;  2EUT A;  4JMW A;  1OAF A;  1H5H A;  1H5I A;  1SCH A;  5ALA A;  1BVA A;  4BM0 A;  1BEQ A;  2GHE X;  1H5A A;  2GB8 A;  4JM9 A;  1JDR A;  2V23 A;  5SW6 A;  5KSF A;  1AEG A;  1ARX A;  3M27 A;  1PA2 A;  1H5C A;  2XJ5 A;  1CMT A;  5JHX A;  2CL4 X;  4FCN A;  4PAE A;  3CCP A;  2Y5A A;  4NVE A;  2RBY X;  1A2F A;  4A5G A;  6ATJ A;  5ABN A;  5KQ0 A;  1QO4 A;  3Q3U A;  1FHF A;  1CYF A;  4XV8 A;  5JQR A;  4C51 A;  5KQ3 A;  4JQK A;  1MK8 A;  1CCB A;  4BM4 A;  2VCN A;  1S73 A;  2RBT X;  1CMU A;  4CVJ A;  1CCC A;  5ABO A;  1AED A;  2WD4 A;  2GHK X;  4NVG B;  4GED A;  3VLK A;  1APX A;  4BM1 A;  1SBM A;  1ZBY A;  2GHH X;  5SYW A;  2RC0 X;  1A2G A;  1IYN A;  5FNE A;  2IA8 A;  2CEP A;  5SXX A;  2GGN X;  1ARW A;  1KXM A;  1H58 A;  1JCI A;  3FM6 A;  2VCS A;  3M23 A;  2XIL A;  4JMV A;  1YYG A;  3M25 A;  2AQD A;  1MN1 A;  1ITK A;  5SX7 A;  5SYK A;  5SX1 A;  1AET A;  5SXT A;  1AEB A;  3E2N A;  5CIH A;  3E2O A;  1AC4 A;  5KQ6 A;  3M2D A;  2B10 A;  1ML2 A;  1DCC A;  5CCP A;  1MKR A;  1AEK A;  4FDQ A;  2EUR A;  4CZR A;  2Y6B A;  5SXQ A;  1KZM A;  2E39 A;  1LYK A;  4P4Q A;  5L02 A;  1AA4 A;  1AEN A;  1BES A;  1BEP A;  1DJ5 A;  1B85 A;  1AEQ A;  1H57 A;  3ZCH A;  2RC1 X;  1BJ9 A;  3VLM A;  5JPR A;  1H55 A;  1OAG A;  3M2G A;  4JPL A;  2XIH A;  5KQK A;  2PCC A;  1YZR A;  2Y6A A;  1CPG A;  1H5K A;  4JQN A;  1V0H X;  2E3A A;  7ATJ A;  3M2C A;  1LYC A;  3VLL A;  5SXR A;  5SX6 A;  1H5E A;  5D6M A;  2AS3 A;  1ARV A;  1LLP A;  1BEJ A;  4CUO A;  4CVI A;  5KQI A;  6CCP A;  4XV7 A;  3FKG A;  2BOQ A;  4NVD A;  4XVA A;  4CZP A;  2CCD A;  1KXN A;  4NVM B;  3M26 A;  4XV6 A;  3ZCG A;  1AEO A;  1ARY A;  5KQH A;  4CCP A;  2AS4 A;  1U2J A;  1DSE A;  3R98 A;  4JMA A;  1HCH A;  5SX3 A;  1UB2 A;  1GWU A;  5SXS A;  1YYD A;  3RRW A;  4A78 A;  5SYY A;  2B0Z A;  4A6Z A;  1CPE A;  4JN0 A;  1GW2 A;  1AEJ A;  4FEF A;  1QGJ A;  3M2H A;  5CJH A;  5SYL A;  3EXB A;  4USC A;  1CPD A;  4NVA A;  3UW8 A;  1ARP A;  5JHY A;  1BGP A;  1H5L A;  3FM4 A;  3X16 A;  1H5D A;  1CCP A;  4NVK B;  1CCL A;  4NVN B;  1DSP A;  3M5Q A;  2VKA A;  3RIW A;  5SXW A;  1B80 A;  2PCB A;  2VNX X;  4A71 A;  2ICV A;  1GZB A;  4A7M A;  4BM2 A;  4JM5 A;  2VO2 X;  3HDL A;  1KOK A;  2RBV X;  1H5M A;  2EUP A;  5SX2 A;  1CK6 A;  1CCJ A;  2YCG A;  2CCP A;  2VNZ X;  1AES A;  3M28 A;  3FJW A;  3M2A A;  4JB4 A;  4JM8 A;  5AOG A;  4NVO B;  1H5J A;  4NFG A;  4OQ7 A;  2EUN A;  1AEF A;  4JMS A;  2GHC X;  4C50 A;  1CCG A;  4ATJ A;  2ANZ A;  2W23 A;  1DS4 A;  5AL9 A;  1DSG A;  4BLL A;  1SJ2 A;  2RBX X;  1ATJ A;  3FM1 A;  4JM6 A;  4JPU A;  2CCA A;  4CZN A;  2AS2 A;  3R99 A;  5EJT A;  1AEU A;  4NVH B;  4JQM A;  4XV4 A; 
#chains in the Genus database with same CATH topology
 1CCK A;  1CPF A;  1U74 A;  1B82 A;  1KRJ A;  5KSK A;  3VLI A;  5CIG A;  1AC8 A;  3WNU A;  2N18 A;  4BLN A;  1AEH A;  1SDQ A;  5CIB A;  4NVL A;  1GWT A;  5CID A;  3VLJ A;  1LGA A;  4JMT A;  4NVI B;  5CIC A;  4CCX A;  2EUO A;  1CCE A;  2B12 A;  1RYC A;  4FCS A;  4CZO A;  3UT2 A;  3CCX A;  1U75 A;  5SYH A;  3M2F A;  3ATJ A;  5JHZ A;  1MNP A;  4H7A A;  2RBU X;  1DJ1 A;  1AEE A;  4GKF A;  2ZCA A;  5SYV A;  3M2I A;  4NVC A;  1YZP A;  5SYI A;  4JMZ A;  1GZA A;  1BEM A;  2RC2 X;  5KQ2 A;  4G05 A;  1W4Y A;  1GWO A;  2XI6 A;  3VLH A;  2X08 A;  4XV5 A;  5SW5 A;  1ZBZ A;  3M8M A;  2RBZ X;  2JTI A;  2AS6 A;  4NVB A;  1CCI A;  4BLX A;  3M2E A;  1GX2 A;  1SOG A;  2XJ6 A;  2AS1 A;  1ARU A;  2RBW X;  7CCP A;  1CMP A;  2BCN A;  1AEV A;  4JQJ A;  2E3B A;  1U2L A;  5AMM A;  5CIF A;  5SYJ A;  5SYX A;  1S6V A;  1MKQ A;  1BEK A;  3FMU A;  3RIV A;  3M2B A;  3ZCY A;  1H3J A;  4BLK A;  1DSO A;  4NVJ B;  5EJX A;  2GHD X;  5SX0 A;  1H5F A;  2CYP A;  1W4W A;  1H5G A;  2YLJ A;  2EUQ A;  5FNB A;  1LY9 A;  1CMQ A;  1STQ A;  2ATJ A;  4JPT A;  4BM3 A;  1Z53 A;  5L05 A;  1MN2 A;  1AEM A;  5L86 A;  2V2E A;  2EUU A;  1LY8 A;  5SX0 B;  2X07 A;  1CCA A;  2XIF A;  2BO5 A;  2VCF X;  5CIE A;  4CZQ A;  1C8I A;  1EBE A;  1QPA A;  1U2K A;  4BLZ A;  3M29 A;  5SYU A;  4BLY A;  5SW4 A;  4JMB A;  4NVF A;  5ABQ A;  2XJ8 A;  2EUS A;  1HSR A;  3WXO A;  2B11 A;  2ZOP A;  2EUT A;  4JMW A;  1OAF A;  1H5H A;  1H5I A;  1SCH A;  5ALA A;  1BVA A;  4BM0 A;  1BEQ A;  2GHE X;  1H5A A;  2GB8 A;  4JM9 A;  1JDR A;  2V23 A;  5SW6 A;  5KSF A;  1AEG A;  1ARX A;  3M27 A;  1PA2 A;  1H5C A;  2XJ5 A;  4H79 A;  1CMT A;  5JHX A;  2CL4 X;  4FCN A;  4JZA A;  4PAE A;  3CCP A;  2Y5A A;  4NVE A;  2RBY X;  1A2F A;  4A5G A;  6ATJ A;  5ABN A;  5KQ0 A;  1QO4 A;  3Q3U A;  1FHF A;  1CYF A;  4XV8 A;  5JQR A;  4C51 A;  5KQ3 A;  4JQK A;  1MK8 A;  1CCB A;  4BM4 A;  2VCN A;  1S73 A;  2RBT X;  5CD4 J;  1CMU A;  4CVJ A;  1CCC A;  5ABO A;  1AED A;  2WD4 A;  2GHK X;  4NVG B;  4GED A;  3VLK A;  1APX A;  4BM1 A;  1SBM A;  1ZBY A;  2GHH X;  5SYW A;  2RC0 X;  1A2G A;  1IYN A;  5FNE A;  2IA8 A;  2CEP A;  5SXX A;  2GGN X;  1ARW A;  1KXM A;  1H58 A;  1JCI A;  3FM6 A;  2VCS A;  3M23 A;  2XIL A;  4JMV A;  1YYG A;  3M25 A;  2AQD A;  1MN1 A;  1ITK A;  5SX7 A;  5SYK A;  5H9E B;  5SX1 A;  1AET A;  5SXT A;  1AEB A;  5H9F B;  3E2N A;  5CIH A;  3E2O A;  1AC4 A;  5KQ6 A;  1ABV A;  3M2D A;  2B10 A;  4QYZ B;  1ML2 A;  2A7U B;  1DCC A;  5CCP A;  1MKR A;  1AEK A;  4FDQ A;  2EUR A;  4CZR A;  2Y6B A;  5SXQ A;  1KZM A;  2E39 A;  1LYK A;  4P4Q A;  5L02 A;  1AA4 A;  1AEN A;  1BES A;  1BEP A;  1DJ5 A;  1B85 A;  3X1L F;  1AEQ A;  1H57 A;  3ZCH A;  2RC1 X;  1BJ9 A;  3VLM A;  5JPR A;  1H55 A;  1OAG A;  3M2G A;  4JPL A;  2XIH A;  5KQK A;  2PCC A;  1YZR A;  2Y6A A;  1CPG A;  1H5K A;  4JQN A;  1V0H X;  2E3A A;  7ATJ A;  3M2C A;  1LYC A;  3VLL A;  5SXR A;  5SX6 A;  1H5E A;  5D6M A;  2AS3 A;  2JMX A;  1ARV A;  1LLP A;  1BEJ A;  4CUO A;  4CVI A;  5KQI A;  6CCP A;  4XV7 A;  3FKG A;  2BOQ A;  4NVD A;  4XVA A;  4CZP A;  2CCD A;  1KXN A;  4NVM B;  3M26 A;  4XV6 A;  3ZCG A;  1AEO A;  1ARY A;  5KQH A;  4CCP A;  2AS4 A;  1U2J A;  1DSE A;  3R98 A;  4JMA A;  1HCH A;  5SX3 A;  1UB2 A;  1GWU A;  5SXS A;  1YYD A;  3RRW A;  4A78 A;  5SYY A;  2B0Z A;  4A6Z A;  1CPE A;  4JN0 A;  1GW2 A;  1AEJ A;  4FEF A;  1QGJ A;  3M2H A;  5CJH A;  5SYL A;  3EXB A;  4USC A;  1CPD A;  4NVA A;  3UW8 A;  1ARP A;  5JHY A;  1BGP A;  1H5L A;  3FM4 A;  3X16 A;  1H5D A;  1CCP A;  4NVK B;  1CCL A;  4NVN B;  1DSP A;  3M5Q A;  2VKA A;  3RIW A;  5SXW A;  1B80 A;  2PCB A;  2VNX X;  4A71 A;  2ICV A;  1GZB A;  4A7M A;  4BM2 A;  4JM5 A;  2VO2 X;  3HDL A;  1KOK A;  2RBV X;  1H5M A;  2EUP A;  5SX2 A;  1CK6 A;  1CCJ A;  2YCG A;  2CCP A;  2VNZ X;  1AES A;  3M28 A;  3FJW A;  3M2A A;  4JB4 A;  4JM8 A;  3WA8 A;  5AOG A;  4NVO B;  1H5J A;  4NFG A;  4OQ7 A;  2EUN A;  1AEF A;  2OEB A;  4JMS A;  2GHC X;  4C50 A;  1CCG A;  4ATJ A;  2ANZ A;  2W23 A;  1DS4 A;  5AL9 A;  2WSS S;  1DSG A;  4BLL A;  1SJ2 A;  2RBX X;  1ATJ A;  3FM1 A;  4JM6 A;  4JPU A;  4U7U B;  2CCA A;  4CZN A;  2AS2 A;  3R99 A;  5EJT A;  1AEU A;  4NVH B;  4JQM A;  4XV4 A; 
#chains in the Genus database with same CATH homology
 1CCK A;  1CPF A;  1U74 A;  1B82 A;  1KRJ A;  5KSK A;  3VLI A;  5CIG A;  1AC8 A;  3WNU A;  2N18 A;  4BLN A;  1AEH A;  1SDQ A;  5CIB A;  4NVL A;  1GWT A;  5CID A;  3VLJ A;  1LGA A;  4JMT A;  4NVI B;  5CIC A;  4CCX A;  2EUO A;  1CCE A;  2B12 A;  1RYC A;  4FCS A;  4CZO A;  3UT2 A;  3CCX A;  1U75 A;  5SYH A;  3M2F A;  3ATJ A;  5JHZ A;  1MNP A;  4H7A A;  2RBU X;  1DJ1 A;  1AEE A;  2ZCA A;  5SYV A;  3M2I A;  4NVC A;  1YZP A;  5SYI A;  4JMZ A;  1GZA A;  1BEM A;  2RC2 X;  5KQ2 A;  4G05 A;  1W4Y A;  1GWO A;  2XI6 A;  3VLH A;  2X08 A;  4XV5 A;  5SW5 A;  1ZBZ A;  3M8M A;  2RBZ X;  2JTI A;  2AS6 A;  4NVB A;  1CCI A;  4BLX A;  3M2E A;  1GX2 A;  1SOG A;  2XJ6 A;  2AS1 A;  1ARU A;  2RBW X;  7CCP A;  1CMP A;  2BCN A;  1AEV A;  4JQJ A;  2E3B A;  1U2L A;  5AMM A;  5CIF A;  5SYJ A;  5SYX A;  1S6V A;  1MKQ A;  1BEK A;  3FMU A;  3RIV A;  3M2B A;  3ZCY A;  1H3J A;  4BLK A;  1DSO A;  4NVJ B;  5EJX A;  2GHD X;  5SX0 A;  1H5F A;  2CYP A;  1W4W A;  1H5G A;  2YLJ A;  2EUQ A;  5FNB A;  1LY9 A;  1CMQ A;  1STQ A;  2ATJ A;  4JPT A;  4BM3 A;  1Z53 A;  5L05 A;  1MN2 A;  1AEM A;  5L86 A;  2V2E A;  2EUU A;  1LY8 A;  5SX0 B;  2X07 A;  1CCA A;  2XIF A;  2VCF X;  5CIE A;  4CZQ A;  1C8I A;  1EBE A;  1QPA A;  1U2K A;  4BLZ A;  3M29 A;  5SYU A;  4BLY A;  5SW4 A;  4JMB A;  4NVF A;  5ABQ A;  2XJ8 A;  2EUS A;  1HSR A;  3WXO A;  2B11 A;  2EUT A;  4JMW A;  1OAF A;  1H5H A;  1H5I A;  1SCH A;  5ALA A;  1BVA A;  4BM0 A;  1BEQ A;  2GHE X;  1H5A A;  2GB8 A;  4JM9 A;  1JDR A;  2V23 A;  5SW6 A;  5KSF A;  1AEG A;  1ARX A;  3M27 A;  1PA2 A;  1H5C A;  2XJ5 A;  4H79 A;  1CMT A;  5JHX A;  2CL4 X;  4FCN A;  4JZA A;  4PAE A;  3CCP A;  2Y5A A;  4NVE A;  2RBY X;  1A2F A;  4A5G A;  6ATJ A;  5ABN A;  5KQ0 A;  1QO4 A;  3Q3U A;  1FHF A;  1CYF A;  4XV8 A;  5JQR A;  4C51 A;  5KQ3 A;  4JQK A;  1MK8 A;  1CCB A;  4BM4 A;  2VCN A;  1S73 A;  2RBT X;  5CD4 J;  1CMU A;  4CVJ A;  1CCC A;  5ABO A;  1AED A;  2WD4 A;  2GHK X;  4NVG B;  4GED A;  3VLK A;  1APX A;  4BM1 A;  1SBM A;  1ZBY A;  2GHH X;  5SYW A;  2RC0 X;  1A2G A;  1IYN A;  5FNE A;  2IA8 A;  2CEP A;  5SXX A;  2GGN X;  1ARW A;  1KXM A;  1H58 A;  1JCI A;  3FM6 A;  2VCS A;  3M23 A;  2XIL A;  4JMV A;  1YYG A;  3M25 A;  2AQD A;  1MN1 A;  1ITK A;  5SX7 A;  5SYK A;  5H9E B;  5SX1 A;  1AET A;  5SXT A;  1AEB A;  5H9F B;  3E2N A;  5CIH A;  3E2O A;  1AC4 A;  5KQ6 A;  3M2D A;  2B10 A;  4QYZ B;  1ML2 A;  1DCC A;  5CCP A;  1MKR A;  1AEK A;  4FDQ A;  2EUR A;  4CZR A;  2Y6B A;  5SXQ A;  1KZM A;  2E39 A;  1LYK A;  4P4Q A;  5L02 A;  1AA4 A;  1AEN A;  1BES A;  1BEP A;  1DJ5 A;  1B85 A;  1AEQ A;  1H57 A;  3ZCH A;  2RC1 X;  1BJ9 A;  3VLM A;  5JPR A;  1H55 A;  1OAG A;  3M2G A;  4JPL A;  2XIH A;  5KQK A;  2PCC A;  1YZR A;  2Y6A A;  1CPG A;  1H5K A;  4JQN A;  1V0H X;  2E3A A;  7ATJ A;  3M2C A;  1LYC A;  3VLL A;  5SXR A;  5SX6 A;  1H5E A;  5D6M A;  2AS3 A;  1ARV A;  1LLP A;  1BEJ A;  4CUO A;  4CVI A;  5KQI A;  6CCP A;  4XV7 A;  3FKG A;  2BOQ A;  4NVD A;  4XVA A;  4CZP A;  2CCD A;  1KXN A;  4NVM B;  3M26 A;  4XV6 A;  3ZCG A;  1AEO A;  1ARY A;  5KQH A;  4CCP A;  2AS4 A;  1U2J A;  1DSE A;  3R98 A;  4JMA A;  1HCH A;  5SX3 A;  1UB2 A;  1GWU A;  5SXS A;  1YYD A;  3RRW A;  4A78 A;  5SYY A;  2B0Z A;  4A6Z A;  1CPE A;  4JN0 A;  1GW2 A;  1AEJ A;  4FEF A;  1QGJ A;  3M2H A;  5CJH A;  5SYL A;  3EXB A;  4USC A;  1CPD A;  4NVA A;  3UW8 A;  1ARP A;  5JHY A;  1BGP A;  1H5L A;  3FM4 A;  3X16 A;  1H5D A;  1CCP A;  4NVK B;  1CCL A;  4NVN B;  1DSP A;  3M5Q A;  2VKA A;  3RIW A;  5SXW A;  1B80 A;  2PCB A;  2VNX X;  4A71 A;  2ICV A;  1GZB A;  4A7M A;  4BM2 A;  4JM5 A;  2VO2 X;  3HDL A;  1KOK A;  2RBV X;  1H5M A;  2EUP A;  5SX2 A;  1CK6 A;  1CCJ A;  2YCG A;  2CCP A;  2VNZ X;  1AES A;  3M28 A;  3FJW A;  3M2A A;  4JB4 A;  4JM8 A;  3WA8 A;  5AOG A;  4NVO B;  1H5J A;  4NFG A;  4OQ7 A;  2EUN A;  1AEF A;  4JMS A;  2GHC X;  4C50 A;  1CCG A;  4ATJ A;  2ANZ A;  2W23 A;  1DS4 A;  5AL9 A;  1DSG A;  4BLL A;  1SJ2 A;  2RBX X;  1ATJ A;  3FM1 A;  4JM6 A;  4JPU A;  4U7U B;  2CCA A;  4CZN A;  2AS2 A;  3R99 A;  5EJT A;  1AEU A;  4NVH B;  4JQM A;  4XV4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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