1AESA

Specificity of ligand binding to a buried polar cavity at the active site of cytochrome c peroxidase (imidazole)
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
291
structure length
291
Chain Sequence
LVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPGGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLEDGITFPKDAPSPFIFKTLEEQGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Saccharomyces cerevisiae
molecule keywords CYTOCHROME C PEROXIDASE
total genus 99
structure length 291
sequence length 291
ec nomenclature ec 1.11.1.5: Cytochrome-c peroxidase.
pdb deposition date 1997-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00141 peroxidase Peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.420.10 Mainly Alpha Orthogonal Bundle Peroxidase; domain 2 Peroxidase, domain 2 1aesA02
1.10.520.10 Mainly Alpha Orthogonal Bundle Peroxidase; domain 1 Peroxidase; domain 1 1aesA01
4XV4A 4CZOA 1U2KA 2EUSA 1H5EA 1CCBA 1U2LA 4JMBA 1AEBA 2CL4X 1DJ5A 5KQKA 6CCPA 1CCLA 5SYJA 5L05A 2RC1X 2E3AA 4NVBA 2XIFA 4NVLA 3M23A 5SXXA 4PAEA 5KQ0A 2B0ZA 2RC2X 4JQMA 4CZPA 1LY9A 1ARYA 3E2OA 1A2FA 5SX6A 4CVIA 1ZBZA 1H5MA 5ABNA 2EUOA 1CCEA 3WNUA 1B85A 5SYKA 1YYGA 4FCSA 1DCCA 1AEFA 1DSPA 4NVGB 1ARWA 1AEUA 4JQKA 5JPRA 1BEPA 1HCHA 3ZCHA 4JMVA 2RBUX 5JQRA 4XV7A 5KQ3A 1ARVA 2EUUA 3M27A 5AMMA 4JM8A 4FEFA 4CCPA 4NVCA 1QGJA 1AEDA 2Y6BA 2AS4A 4NVKB 1H58A 1BEMA 1BEJA 1MN2A 4BLLA 4BM0A 3M2DA 1W4WA 7CCPA 1AEEA 3ZCYA 4XV5A 5SX0B 5JHYA 4A7MA 1BVAA 4XVAA 1YYDA 1H5IA 1CCGA 2GHDX 1ARPA 2EURA 1H5FA 5KQ6A 3RIVA 1KRJA 1BEQA 4G05A 3VLIA 4CUOA 5KSKA 1CCAA 2WD4A 3FJWA 3M2AA 4NVAA 5SW6A 1ARXA 4A78A 1BJ9A 2IA8A 2V2EA 2EUNA 1C8IA 3FM4A 4CVJA 4NVNB 1HSRA 1H55A 4CCXA 1KOKA 2BCNA 5L86A 5SYLA 4NVHB 1MNPA 2RBWX 2B12A 4P4QA 1LYKA 4GEDA 1CMUA 1H5KA 5SX2A 5CIFA 2XJ6A 1BESA 2VCSA 4JMTA 1GWOA 1AEOA 2XILA 1CPFA 2N18A 5SYHA 1KXMA 5SXQA 3FMUA 1JDRA 4NFGA 3FM1A 2VO2X 1AA4A 1AEJA 4NVJB 1AEKA 1AESA 1CK6A 5SX0A 5SX1A 5ALAA 1AEGA 5SXSA 4JQNA 3UW8A 1OAGA 1CMTA 1BGPA 5ABOA 4BLXA 1H3JA 5CIEA 4USCA 4JM5A 3VLJA 2CCAA 3ZCGA 1AC4A 3FKGA 1MKRA 5ABQA 2E3BA 1APXA 5SYXA 5SYYA 3M25A 1CCKA 1LGAA 4NVOB 1CPEA 4NVFA 2JTIA 7ATJA 5KQ2A 1ATJA 4NVDA 4JPUA 2YCGA 1H5AA 5KSFA 2VKAA 4ATJA 2AS1A 2CEPA 4JMAA 1ARUA 4JB4A 6ATJA 2ATJA 2XI6A 5CJHA 1LY8A 1GW2A 4XV8A 4NVMB 1ML2A 5FNBA 5KQHA 2XJ8A 5SX3A 5L02A 1CMQA 4BM3A 1QO4A 1GZBA 2B10A 3VLLA 3EXBA 1H5JA 1KZMA 4C51A 5D6MA 1IYNA 3M5QA 1B80A 1CCCA 3RIWA 2XJ5A 5JHZA 2YLJA 2GGNX 1MKQA 1H5DA 2Y5AA 4FCNA 1LLPA 2GB8A 3R98A 4C50A 5SXRA 2GHKX 3UT2A 1A2GA 3HDLA 4JMSA 5SX7A 2PCBA 3M2FA 4A71A 2RBYX 3CCPA 1AC8A 5SXTA 3M2EA 2VNXX 1ZBYA 5CIBA 2RBTX 2W23A 4CZRA 1STQA 5EJXA 4NVIB 2XIHA 4JMWA 5AOGA 4BLZA 3M2BA 5CIGA 1EBEA 1FHFA 1AEVA 1DJ1A 1S6VA 1YZPA 4CZNA 4BM2A 1W4YA 2RBVX 5FNEA 2EUPA 4BLNA 4JPLA 4JM6A 2E39A 4XV6A 4FDQA 1CPGA 1LYCA 1YZRA 2EUQA 4BM1A 4CZQA 2RC0X 3Q3UA 1PA2A 2ICVA 3VLKA 4JMZA 5SXWA 3X16A 1MK8A 4A5GA 4A6ZA 1GZAA 5AL9A 1AENA 3M2IA 3CCXA 1BEKA 2GHHX 1RYCA 2EUTA 1CCIA 1S73A 4JPTA 5SYWA 3R99A 4BM4A 2RBZX 4BLYA 2VCNA 1H5HA 1U2JA 1DSEA 2ANZA 1V0HX 4JN0A 1H57A 1AEHA 1CYFA 2B11A 1H5CA 1GWTA 5SYIA 1GWUA 1JCIA 1SDQA 2CYPA 2PCCA 3FM6A 1SJ2A 5CCPA 1QPAA 3ATJA 3M26A 5JHXA 1DSGA 3M2CA 5SW5A 1CMPA 3VLMA 3M8MA 5SW4A 2GHCX 3RRWA 1H5LA 5SYUA 2AS3A 1KXNA 4OQ7A 2GHEX 5EJTA 2X07A 2AS6A 5CICA 1GX2A 1B82A 3M2HA 2CCPA 1AEQA 1U74A 3M28A 4BLKA 1AEMA 5CIHA 3M29A 1CCJA 2VCFX 1UB2A 3VLHA 1U75A 1CPDA 2CCDA 3WXOA 1DS4A 2Y6AA 1SOGA 1Z53A 5SYVA 1DSOA 3M2GA 2X08A 1H5GA 2RBXX 3E2NA 1MN1A 2AQDA 2AS2A 2V23A 2BOQA 4JM9A 1AETA 5CIDA 5KQIA 4NVEA 1OAFA 1CCPA 1ITKA 2VNZX 1SCHA 4JQJA 1SBMA
chains in the Genus database with same CATH superfamily
4XV4A 2ZOPA 4CZOA 1U2KA 2EUSA 1H5EA 1CCBA 1U2LA 4JMBA 1AEBA 2CL4X 1DJ5A 5KQKA 6CCPA 1CCLA 5SYJA 5L05A 2RC1X 2E3AA 4NVBA 2XIFA 4NVLA 3M23A 5SXXA 4PAEA 5KQ0A 2B0ZA 2RC2X 4JQMA 4CZPA 1LY9A 1ARYA 3E2OA 1A2FA 5SX6A 4CVIA 1ZBZA 1H5MA 5ABNA 2EUOA 1CCEA 3WNUA 1B85A 5SYKA 1YYGA 4FCSA 2ZCAA 1DCCA 1AEFA 1DSPA 4NVGB 1ARWA 1AEUA 4JQKA 5JPRA 1BEPA 1HCHA 3ZCHA 4JMVA 2RBUX 5JQRA 4XV7A 5KQ3A 1ARVA 2EUUA 3M27A 5AMMA 4JM8A 4FEFA 4CCPA 4NVCA 1QGJA 1AEDA 4U7UB 2Y6BA 2AS4A 4NVKB 1H58A 1BEMA 1BEJA 1MN2A 4BLLA 4BM0A 3M2DA 1W4WA 7CCPA 1AEEA 3ZCYA 4XV5A 5SX0B 5JHYA 4A7MA 1BVAA 4XVAA 1YYDA 1H5IA 1CCGA 2GHDX 1ARPA 2EURA 1H5FA 5KQ6A 3RIVA 4H79A 1KRJA 1BEQA 4G05A 3VLIA 4CUOA 5KSKA 1CCAA 2WD4A 3FJWA 3M2AA 4NVAA 5SW6A 1ARXA 4A78A 1BJ9A 2IA8A 2V2EA 2EUNA 1C8IA 3FM4A 4CVJA 4NVNB 1HSRA 1H55A 4CCXA 1KOKA 2BCNA 5CD4J 5L86A 5SYLA 4NVHB 1MNPA 2RBWX 2B12A 4P4QA 2JMXA 1LYKA 4GEDA 1CMUA 1H5KA 5SX2A 5CIFA 2XJ6A 2OEBA 1BESA 2VCSA 4JMTA 1GWOA 1AEOA 2XILA 1CPFA 2N18A 5SYHA 1KXMA 5SXQA 3FMUA 1JDRA 4NFGA 3FM1A 2VO2X 1AA4A 1AEJA 4NVJB 1AEKA 1AESA 1CK6A 5SX0A 5SX1A 5ALAA 1AEGA 4H7AA 5SXSA 4JQNA 3UW8A 1OAGA 1CMTA 1BGPA 5ABOA 4BLXA 1H3JA 5CIEA 4USCA 4JM5A 3VLJA 2CCAA 3ZCGA 1AC4A 3FKGA 1MKRA 5ABQA 2E3BA 1APXA 5SYXA 5SYYA 3M25A 1CCKA 1LGAA 4NVOB 1CPEA 4NVFA 2JTIA 7ATJA 5KQ2A 1ATJA 4NVDA 4QYZB 4JPUA 2YCGA 1H5AA 5KSFA 2VKAA 4ATJA 2AS1A 2CEPA 4JMAA 1ARUA 4JB4A 6ATJA 2ATJA 2XI6A 5CJHA 1LY8A 1GW2A 4XV8A 4NVMB 1ML2A 5FNBA 5KQHA 2XJ8A 5SX3A 5L02A 2A7UB 1CMQA 4BM3A 1QO4A 1GZBA 2B10A 3VLLA 3EXBA 1H5JA 1KZMA 4C51A 5D6MA 1IYNA 3M5QA 1B80A 1CCCA 3RIWA 2XJ5A 5JHZA 2YLJA 2GGNX 1MKQA 1H5DA 2Y5AA 4FCNA 1LLPA 2GB8A 3R98A 4C50A 5SXRA 2GHKX 3UT2A 1A2GA 3HDLA 4JMSA 5SX7A 2PCBA 3M2FA 4A71A 2RBYX 3CCPA 1AC8A 5SXTA 3M2EA 2VNXX 1ZBYA 5CIBA 4JZAA 2RBTX 2W23A 4CZRA 1STQA 5EJXA 4NVIB 2XIHA 4JMWA 5AOGA 4BLZA 3M2BA 5CIGA 1EBEA 1FHFA 1AEVA 1DJ1A 1S6VA 1YZPA 4CZNA 4BM2A 1W4YA 2RBVX 5FNEA 2EUPA 4BLNA 2BO5A 4JPLA 4JM6A 2E39A 4XV6A 4FDQA 1CPGA 1LYCA 1YZRA 2EUQA 4BM1A 4CZQA 2RC0X 3Q3UA 1PA2A 2ICVA 3VLKA 4JMZA 5SXWA 3X16A 1MK8A 4A5GA 4A6ZA 1GZAA 5AL9A 4GKFA 1AENA 3M2IA 3CCXA 1BEKA 2GHHX 1RYCA 2EUTA 1CCIA 1S73A 4JPTA 5SYWA 3R99A 4BM4A 5H9EB 2RBZX 4BLYA 2VCNA 1H5HA 1U2JA 1DSEA 2ANZA 1V0HX 4JN0A 3WA8A 1H57A 1AEHA 1CYFA 2B11A 1H5CA 1ABVA 1GWTA 5SYIA 1GWUA 1JCIA 1SDQA 2CYPA 2PCCA 3FM6A 1SJ2A 5CCPA 1QPAA 3ATJA 3M26A 5JHXA 1DSGA 3M2CA 5SW5A 1CMPA 3VLMA 3M8MA 5SW4A 2GHCX 3RRWA 1H5LA 5SYUA 2AS3A 1KXNA 4OQ7A 2GHEX 5EJTA 2X07A 2AS6A 5CICA 1GX2A 1B82A 3M2HA 2CCPA 1AEQA 1U74A 3M28A 4BLKA 1AEMA 3X1LF 5CIHA 3M29A 1CCJA 2VCFX 1UB2A 3VLHA 1U75A 1CPDA 2CCDA 3WXOA 1DS4A 2WSSS 2Y6AA 1SOGA 1Z53A 5SYVA 1DSOA 3M2GA 2X08A 1H5GA 2RBXX 3E2NA 1MN1A 2AQDA 2AS2A 2V23A 2BOQA 4JM9A 1AETA 5CIDA 5KQIA 4NVEA 1OAFA 5H9FB 1CCPA 1ITKA 2VNZX 1SCHA 4JQJA 1SBMA
chains in the Genus database with same CATH topology
4XV4A 4CZOA 1U2KA 2EUSA 1H5EA 1CCBA 1U2LA 4JMBA 1AEBA 2CL4X 1DJ5A 5KQKA 6CCPA 1CCLA 5SYJA 5L05A 2RC1X 2E3AA 4NVBA 2XIFA 4NVLA 3M23A 5SXXA 4PAEA 5KQ0A 2B0ZA 2RC2X 4JQMA 4CZPA 1LY9A 1ARYA 3E2OA 1A2FA 5SX6A 4CVIA 1ZBZA 1H5MA 5ABNA 2EUOA 1CCEA 3WNUA 1B85A 5SYKA 1YYGA 4FCSA 2ZCAA 1DCCA 1AEFA 1DSPA 4NVGB 1ARWA 1AEUA 4JQKA 5JPRA 1BEPA 1HCHA 3ZCHA 4JMVA 2RBUX 5JQRA 4XV7A 5KQ3A 1ARVA 2EUUA 3M27A 5AMMA 4JM8A 4FEFA 4CCPA 4NVCA 1QGJA 1AEDA 4U7UB 2Y6BA 2AS4A 4NVKB 1H58A 1BEMA 1BEJA 1MN2A 4BLLA 4BM0A 3M2DA 1W4WA 7CCPA 1AEEA 3ZCYA 4XV5A 5SX0B 5JHYA 4A7MA 1BVAA 4XVAA 1YYDA 1H5IA 1CCGA 2GHDX 1ARPA 2EURA 1H5FA 5KQ6A 3RIVA 4H79A 1KRJA 1BEQA 4G05A 3VLIA 4CUOA 5KSKA 1CCAA 2WD4A 3FJWA 3M2AA 4NVAA 5SW6A 1ARXA 4A78A 1BJ9A 2IA8A 2V2EA 2EUNA 1C8IA 3FM4A 4CVJA 4NVNB 1HSRA 1H55A 4CCXA 1KOKA 2BCNA 5CD4J 5L86A 5SYLA 4NVHB 1MNPA 2RBWX 2B12A 4P4QA 1LYKA 4GEDA 1CMUA 1H5KA 5SX2A 5CIFA 2XJ6A 1BESA 2VCSA 4JMTA 1GWOA 1AEOA 2XILA 1CPFA 2N18A 5SYHA 1KXMA 5SXQA 3FMUA 1JDRA 4NFGA 3FM1A 2VO2X 1AA4A 1AEJA 4NVJB 1AEKA 1AESA 1CK6A 5SX0A 5SX1A 5ALAA 1AEGA 4H7AA 5SXSA 4JQNA 3UW8A 1OAGA 1CMTA 1BGPA 5ABOA 4BLXA 1H3JA 5CIEA 4USCA 4JM5A 3VLJA 2CCAA 3ZCGA 1AC4A 3FKGA 1MKRA 5ABQA 2E3BA 1APXA 5SYXA 5SYYA 3M25A 1CCKA 1LGAA 4NVOB 1CPEA 4NVFA 2JTIA 7ATJA 5KQ2A 1ATJA 4NVDA 4QYZB 4JPUA 2YCGA 1H5AA 5KSFA 2VKAA 4ATJA 2AS1A 2CEPA 4JMAA 1ARUA 4JB4A 6ATJA 2ATJA 2XI6A 5CJHA 1LY8A 1GW2A 4XV8A 4NVMB 1ML2A 5FNBA 5KQHA 2XJ8A 5SX3A 5L02A 1CMQA 4BM3A 1QO4A 1GZBA 2B10A 3VLLA 3EXBA 1H5JA 1KZMA 4C51A 5D6MA 1IYNA 3M5QA 1B80A 1CCCA 3RIWA 2XJ5A 5JHZA 2YLJA 2GGNX 1MKQA 1H5DA 2Y5AA 4FCNA 1LLPA 2GB8A 3R98A 4C50A 5SXRA 2GHKX 3UT2A 1A2GA 3HDLA 4JMSA 5SX7A 2PCBA 3M2FA 4A71A 2RBYX 3CCPA 1AC8A 5SXTA 3M2EA 2VNXX 1ZBYA 5CIBA 4JZAA 2RBTX 2W23A 4CZRA 1STQA 5EJXA 4NVIB 2XIHA 4JMWA 5AOGA 4BLZA 3M2BA 5CIGA 1EBEA 1FHFA 1AEVA 1DJ1A 1S6VA 1YZPA 4CZNA 4BM2A 1W4YA 2RBVX 5FNEA 2EUPA 4BLNA 4JPLA 4JM6A 2E39A 4XV6A 4FDQA 1CPGA 1LYCA 1YZRA 2EUQA 4BM1A 4CZQA 2RC0X 3Q3UA 1PA2A 2ICVA 3VLKA 4JMZA 5SXWA 3X16A 1MK8A 4A5GA 4A6ZA 1GZAA 5AL9A 1AENA 3M2IA 3CCXA 1BEKA 2GHHX 1RYCA 2EUTA 1CCIA 1S73A 4JPTA 5SYWA 3R99A 4BM4A 5H9EB 2RBZX 4BLYA 2VCNA 1H5HA 1U2JA 1DSEA 2ANZA 1V0HX 4JN0A 3WA8A 1H57A 1AEHA 1CYFA 2B11A 1H5CA 1GWTA 5SYIA 1GWUA 1JCIA 1SDQA 2CYPA 2PCCA 3FM6A 1SJ2A 5CCPA 1QPAA 3ATJA 3M26A 5JHXA 1DSGA 3M2CA 5SW5A 1CMPA 3VLMA 3M8MA 5SW4A 2GHCX 3RRWA 1H5LA 5SYUA 2AS3A 1KXNA 4OQ7A 2GHEX 5EJTA 2X07A 2AS6A 5CICA 1GX2A 1B82A 3M2HA 2CCPA 1AEQA 1U74A 3M28A 4BLKA 1AEMA 5CIHA 3M29A 1CCJA 2VCFX 1UB2A 3VLHA 1U75A 1CPDA 2CCDA 3WXOA 1DS4A 2Y6AA 1SOGA 1Z53A 5SYVA 1DSOA 3M2GA 2X08A 1H5GA 2RBXX 3E2NA 1MN1A 2AQDA 2AS2A 2V23A 2BOQA 4JM9A 1AETA 5CIDA 5KQIA 4NVEA 1OAFA 5H9FB 1CCPA 1ITKA 2VNZX 1SCHA 4JQJA 1SBMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XV4 A;  4CZO A;  1U2K A;  2EUS A;  1H5E A;  1CCB A;  1U2L A;  4JMB A;  1AEB A;  2CL4 X;  1DJ5 A;  5KQK A;  6CCP A;  1CCL A;  5SYJ A;  5L05 A;  2RC1 X;  2E3A A;  4NVB A;  2XIF A;  4NVL A;  3M23 A;  5SXX A;  4PAE A;  5KQ0 A;  2B0Z A;  2RC2 X;  4JQM A;  4CZP A;  1LY9 A;  1ARY A;  3E2O A;  1A2F A;  5SX6 A;  4CVI A;  1ZBZ A;  1H5M A;  5ABN A;  2EUO A;  1CCE A;  3WNU A;  1B85 A;  5SYK A;  1YYG A;  4FCS A;  1DCC A;  1AEF A;  1DSP A;  4NVG B;  1ARW A;  1AEU A;  4JQK A;  5JPR A;  1BEP A;  1HCH A;  3ZCH A;  4JMV A;  2RBU X;  5JQR A;  4XV7 A;  5KQ3 A;  1ARV A;  2EUU A;  3M27 A;  5AMM A;  4JM8 A;  4FEF A;  4CCP A;  4NVC A;  1QGJ A;  1AED A;  2Y6B A;  2AS4 A;  4NVK B;  1H58 A;  1BEM A;  1BEJ A;  1MN2 A;  4BLL A;  4BM0 A;  3M2D A;  1W4W A;  7CCP A;  1AEE A;  3ZCY A;  4XV5 A;  5SX0 B;  5JHY A;  4A7M A;  1BVA A;  4XVA A;  1YYD A;  1H5I A;  1CCG A;  2GHD X;  1ARP A;  2EUR A;  1H5F A;  5KQ6 A;  3RIV A;  1KRJ A;  1BEQ A;  4G05 A;  3VLI A;  4CUO A;  5KSK A;  1CCA A;  2WD4 A;  3FJW A;  3M2A A;  4NVA A;  5SW6 A;  1ARX A;  4A78 A;  1BJ9 A;  2IA8 A;  2V2E A;  2EUN A;  1C8I A;  3FM4 A;  4CVJ A;  4NVN B;  1HSR A;  1H55 A;  4CCX A;  1KOK A;  2BCN A;  5L86 A;  5SYL A;  4NVH B;  1MNP A;  2RBW X;  2B12 A;  4P4Q A;  1LYK A;  4GED A;  1CMU A;  1H5K A;  5SX2 A;  5CIF A;  2XJ6 A;  1BES A;  2VCS A;  4JMT A;  1GWO A;  1AEO A;  2XIL A;  1CPF A;  2N18 A;  5SYH A;  1KXM A;  5SXQ A;  3FMU A;  1JDR A;  4NFG A;  3FM1 A;  2VO2 X;  1AA4 A;  1AEJ A;  4NVJ B;  1AEK A;  1AES A;  1CK6 A;  5SX0 A;  5SX1 A;  5ALA A;  1AEG A;  5SXS A;  4JQN A;  3UW8 A;  1OAG A;  1CMT A;  1BGP A;  5ABO A;  4BLX A;  1H3J A;  5CIE A;  4USC A;  4JM5 A;  3VLJ A;  2CCA A;  3ZCG A;  1AC4 A;  3FKG A;  1MKR A;  5ABQ A;  2E3B A;  1APX A;  5SYX A;  5SYY A;  3M25 A;  1CCK A;  1LGA A;  4NVO B;  1CPE A;  4NVF A;  2JTI A;  7ATJ A;  5KQ2 A;  1ATJ A;  4NVD A;  4JPU A;  2YCG A;  1H5A A;  5KSF A;  2VKA A;  4ATJ A;  2AS1 A;  2CEP A;  4JMA A;  1ARU A;  4JB4 A;  6ATJ A;  2ATJ A;  2XI6 A;  5CJH A;  1LY8 A;  1GW2 A;  4XV8 A;  4NVM B;  1ML2 A;  5FNB A;  5KQH A;  2XJ8 A;  5SX3 A;  5L02 A;  1CMQ A;  4BM3 A;  1QO4 A;  1GZB A;  2B10 A;  3VLL A;  3EXB A;  1H5J A;  1KZM A;  4C51 A;  5D6M A;  1IYN A;  3M5Q A;  1B80 A;  1CCC A;  3RIW A;  2XJ5 A;  5JHZ A;  2YLJ A;  2GGN X;  1MKQ A;  1H5D A;  2Y5A A;  4FCN A;  1LLP A;  2GB8 A;  3R98 A;  4C50 A;  5SXR A;  2GHK X;  3UT2 A;  1A2G A;  3HDL A;  4JMS A;  5SX7 A;  2PCB A;  3M2F A;  4A71 A;  2RBY X;  3CCP A;  1AC8 A;  5SXT A;  3M2E A;  2VNX X;  1ZBY A;  5CIB A;  2RBT X;  2W23 A;  4CZR A;  1STQ A;  5EJX A;  4NVI B;  2XIH A;  4JMW A;  5AOG A;  4BLZ A;  3M2B A;  5CIG A;  1EBE A;  1FHF A;  1AEV A;  1DJ1 A;  1S6V A;  1YZP A;  4CZN A;  4BM2 A;  1W4Y A;  2RBV X;  5FNE A;  2EUP A;  4BLN A;  4JPL A;  4JM6 A;  2E39 A;  4XV6 A;  4FDQ A;  1CPG A;  1LYC A;  1YZR A;  2EUQ A;  4BM1 A;  4CZQ A;  2RC0 X;  3Q3U A;  1PA2 A;  2ICV A;  3VLK A;  4JMZ A;  5SXW A;  3X16 A;  1MK8 A;  4A5G A;  4A6Z A;  1GZA A;  5AL9 A;  1AEN A;  3M2I A;  3CCX A;  1BEK A;  2GHH X;  1RYC A;  2EUT A;  1CCI A;  1S73 A;  4JPT A;  5SYW A;  3R99 A;  4BM4 A;  2RBZ X;  4BLY A;  2VCN A;  1H5H A;  1U2J A;  1DSE A;  2ANZ A;  1V0H X;  4JN0 A;  1H57 A;  1AEH A;  1CYF A;  2B11 A;  1H5C A;  1GWT A;  5SYI A;  1GWU A;  1JCI A;  1SDQ A;  2CYP A;  2PCC A;  3FM6 A;  1SJ2 A;  5CCP A;  1QPA A;  3ATJ A;  3M26 A;  5JHX A;  1DSG A;  3M2C A;  5SW5 A;  1CMP A;  3VLM A;  3M8M A;  5SW4 A;  2GHC X;  3RRW A;  1H5L A;  5SYU A;  2AS3 A;  1KXN A;  4OQ7 A;  2GHE X;  5EJT A;  2X07 A;  2AS6 A;  5CIC A;  1GX2 A;  1B82 A;  3M2H A;  2CCP A;  1AEQ A;  1U74 A;  3M28 A;  4BLK A;  1AEM A;  5CIH A;  3M29 A;  1CCJ A;  2VCF X;  1UB2 A;  3VLH A;  1U75 A;  1CPD A;  2CCD A;  3WXO A;  1DS4 A;  2Y6A A;  1SOG A;  1Z53 A;  5SYV A;  1DSO A;  3M2G A;  2X08 A;  1H5G A;  2RBX X;  3E2N A;  1MN1 A;  2AQD A;  2AS2 A;  2V23 A;  2BOQ A;  4JM9 A;  1AET A;  5CID A;  5KQI A;  4NVE A;  1OAF A;  1CCP A;  1ITK A;  2VNZ X;  1SCH A;  4JQJ A;  1SBM A; 
#chains in the Genus database with same CATH topology
 4XV4 A;  2ZOP A;  4CZO A;  1U2K A;  2EUS A;  1H5E A;  1CCB A;  1U2L A;  4JMB A;  1AEB A;  2CL4 X;  1DJ5 A;  5KQK A;  6CCP A;  1CCL A;  5SYJ A;  5L05 A;  2RC1 X;  2E3A A;  4NVB A;  2XIF A;  4NVL A;  3M23 A;  5SXX A;  4PAE A;  5KQ0 A;  2B0Z A;  2RC2 X;  4JQM A;  4CZP A;  1LY9 A;  1ARY A;  3E2O A;  1A2F A;  5SX6 A;  4CVI A;  1ZBZ A;  1H5M A;  5ABN A;  2EUO A;  1CCE A;  3WNU A;  1B85 A;  5SYK A;  1YYG A;  4FCS A;  2ZCA A;  1DCC A;  1AEF A;  1DSP A;  4NVG B;  1ARW A;  1AEU A;  4JQK A;  5JPR A;  1BEP A;  1HCH A;  3ZCH A;  4JMV A;  2RBU X;  5JQR A;  4XV7 A;  5KQ3 A;  1ARV A;  2EUU A;  3M27 A;  5AMM A;  4JM8 A;  4FEF A;  4CCP A;  4NVC A;  1QGJ A;  1AED A;  4U7U B;  2Y6B A;  2AS4 A;  4NVK B;  1H58 A;  1BEM A;  1BEJ A;  1MN2 A;  4BLL A;  4BM0 A;  3M2D A;  1W4W A;  7CCP A;  1AEE A;  3ZCY A;  4XV5 A;  5SX0 B;  5JHY A;  4A7M A;  1BVA A;  4XVA A;  1YYD A;  1H5I A;  1CCG A;  2GHD X;  1ARP A;  2EUR A;  1H5F A;  5KQ6 A;  3RIV A;  4H79 A;  1KRJ A;  1BEQ A;  4G05 A;  3VLI A;  4CUO A;  5KSK A;  1CCA A;  2WD4 A;  3FJW A;  3M2A A;  4NVA A;  5SW6 A;  1ARX A;  4A78 A;  1BJ9 A;  2IA8 A;  2V2E A;  2EUN A;  1C8I A;  3FM4 A;  4CVJ A;  4NVN B;  1HSR A;  1H55 A;  4CCX A;  1KOK A;  2BCN A;  5CD4 J;  5L86 A;  5SYL A;  4NVH B;  1MNP A;  2RBW X;  2B12 A;  4P4Q A;  2JMX A;  1LYK A;  4GED A;  1CMU A;  1H5K A;  5SX2 A;  5CIF A;  2XJ6 A;  2OEB A;  1BES A;  2VCS A;  4JMT A;  1GWO A;  1AEO A;  2XIL A;  1CPF A;  2N18 A;  5SYH A;  1KXM A;  5SXQ A;  3FMU A;  1JDR A;  4NFG A;  3FM1 A;  2VO2 X;  1AA4 A;  1AEJ A;  4NVJ B;  1AEK A;  1AES A;  1CK6 A;  5SX0 A;  5SX1 A;  5ALA A;  1AEG A;  4H7A A;  5SXS A;  4JQN A;  3UW8 A;  1OAG A;  1CMT A;  1BGP A;  5ABO A;  4BLX A;  1H3J A;  5CIE A;  4USC A;  4JM5 A;  3VLJ A;  2CCA A;  3ZCG A;  1AC4 A;  3FKG A;  1MKR A;  5ABQ A;  2E3B A;  1APX A;  5SYX A;  5SYY A;  3M25 A;  1CCK A;  1LGA A;  4NVO B;  1CPE A;  4NVF A;  2JTI A;  7ATJ A;  5KQ2 A;  1ATJ A;  4NVD A;  4QYZ B;  4JPU A;  2YCG A;  1H5A A;  5KSF A;  2VKA A;  4ATJ A;  2AS1 A;  2CEP A;  4JMA A;  1ARU A;  4JB4 A;  6ATJ A;  2ATJ A;  2XI6 A;  5CJH A;  1LY8 A;  1GW2 A;  4XV8 A;  4NVM B;  1ML2 A;  5FNB A;  5KQH A;  2XJ8 A;  5SX3 A;  5L02 A;  2A7U B;  1CMQ A;  4BM3 A;  1QO4 A;  1GZB A;  2B10 A;  3VLL A;  3EXB A;  1H5J A;  1KZM A;  4C51 A;  5D6M A;  1IYN A;  3M5Q A;  1B80 A;  1CCC A;  3RIW A;  2XJ5 A;  5JHZ A;  2YLJ A;  2GGN X;  1MKQ A;  1H5D A;  2Y5A A;  4FCN A;  1LLP A;  2GB8 A;  3R98 A;  4C50 A;  5SXR A;  2GHK X;  3UT2 A;  1A2G A;  3HDL A;  4JMS A;  5SX7 A;  2PCB A;  3M2F A;  4A71 A;  2RBY X;  3CCP A;  1AC8 A;  5SXT A;  3M2E A;  2VNX X;  1ZBY A;  5CIB A;  4JZA A;  2RBT X;  2W23 A;  4CZR A;  1STQ A;  5EJX A;  4NVI B;  2XIH A;  4JMW A;  5AOG A;  4BLZ A;  3M2B A;  5CIG A;  1EBE A;  1FHF A;  1AEV A;  1DJ1 A;  1S6V A;  1YZP A;  4CZN A;  4BM2 A;  1W4Y A;  2RBV X;  5FNE A;  2EUP A;  4BLN A;  2BO5 A;  4JPL A;  4JM6 A;  2E39 A;  4XV6 A;  4FDQ A;  1CPG A;  1LYC A;  1YZR A;  2EUQ A;  4BM1 A;  4CZQ A;  2RC0 X;  3Q3U A;  1PA2 A;  2ICV A;  3VLK A;  4JMZ A;  5SXW A;  3X16 A;  1MK8 A;  4A5G A;  4A6Z A;  1GZA A;  5AL9 A;  4GKF A;  1AEN A;  3M2I A;  3CCX A;  1BEK A;  2GHH X;  1RYC A;  2EUT A;  1CCI A;  1S73 A;  4JPT A;  5SYW A;  3R99 A;  4BM4 A;  5H9E B;  2RBZ X;  4BLY A;  2VCN A;  1H5H A;  1U2J A;  1DSE A;  2ANZ A;  1V0H X;  4JN0 A;  3WA8 A;  1H57 A;  1AEH A;  1CYF A;  2B11 A;  1H5C A;  1ABV A;  1GWT A;  5SYI A;  1GWU A;  1JCI A;  1SDQ A;  2CYP A;  2PCC A;  3FM6 A;  1SJ2 A;  5CCP A;  1QPA A;  3ATJ A;  3M26 A;  5JHX A;  1DSG A;  3M2C A;  5SW5 A;  1CMP A;  3VLM A;  3M8M A;  5SW4 A;  2GHC X;  3RRW A;  1H5L A;  5SYU A;  2AS3 A;  1KXN A;  4OQ7 A;  2GHE X;  5EJT A;  2X07 A;  2AS6 A;  5CIC A;  1GX2 A;  1B82 A;  3M2H A;  2CCP A;  1AEQ A;  1U74 A;  3M28 A;  4BLK A;  1AEM A;  3X1L F;  5CIH A;  3M29 A;  1CCJ A;  2VCF X;  1UB2 A;  3VLH A;  1U75 A;  1CPD A;  2CCD A;  3WXO A;  1DS4 A;  2WSS S;  2Y6A A;  1SOG A;  1Z53 A;  5SYV A;  1DSO A;  3M2G A;  2X08 A;  1H5G A;  2RBX X;  3E2N A;  1MN1 A;  2AQD A;  2AS2 A;  2V23 A;  2BOQ A;  4JM9 A;  1AET A;  5CID A;  5KQI A;  4NVE A;  1OAF A;  5H9F B;  1CCP A;  1ITK A;  2VNZ X;  1SCH A;  4JQJ A;  1SBM A; 
#chains in the Genus database with same CATH homology
 4XV4 A;  4CZO A;  1U2K A;  2EUS A;  1H5E A;  1CCB A;  1U2L A;  4JMB A;  1AEB A;  2CL4 X;  1DJ5 A;  5KQK A;  6CCP A;  1CCL A;  5SYJ A;  5L05 A;  2RC1 X;  2E3A A;  4NVB A;  2XIF A;  4NVL A;  3M23 A;  5SXX A;  4PAE A;  5KQ0 A;  2B0Z A;  2RC2 X;  4JQM A;  4CZP A;  1LY9 A;  1ARY A;  3E2O A;  1A2F A;  5SX6 A;  4CVI A;  1ZBZ A;  1H5M A;  5ABN A;  2EUO A;  1CCE A;  3WNU A;  1B85 A;  5SYK A;  1YYG A;  4FCS A;  2ZCA A;  1DCC A;  1AEF A;  1DSP A;  4NVG B;  1ARW A;  1AEU A;  4JQK A;  5JPR A;  1BEP A;  1HCH A;  3ZCH A;  4JMV A;  2RBU X;  5JQR A;  4XV7 A;  5KQ3 A;  1ARV A;  2EUU A;  3M27 A;  5AMM A;  4JM8 A;  4FEF A;  4CCP A;  4NVC A;  1QGJ A;  1AED A;  4U7U B;  2Y6B A;  2AS4 A;  4NVK B;  1H58 A;  1BEM A;  1BEJ A;  1MN2 A;  4BLL A;  4BM0 A;  3M2D A;  1W4W A;  7CCP A;  1AEE A;  3ZCY A;  4XV5 A;  5SX0 B;  5JHY A;  4A7M A;  1BVA A;  4XVA A;  1YYD A;  1H5I A;  1CCG A;  2GHD X;  1ARP A;  2EUR A;  1H5F A;  5KQ6 A;  3RIV A;  4H79 A;  1KRJ A;  1BEQ A;  4G05 A;  3VLI A;  4CUO A;  5KSK A;  1CCA A;  2WD4 A;  3FJW A;  3M2A A;  4NVA A;  5SW6 A;  1ARX A;  4A78 A;  1BJ9 A;  2IA8 A;  2V2E A;  2EUN A;  1C8I A;  3FM4 A;  4CVJ A;  4NVN B;  1HSR A;  1H55 A;  4CCX A;  1KOK A;  2BCN A;  5CD4 J;  5L86 A;  5SYL A;  4NVH B;  1MNP A;  2RBW X;  2B12 A;  4P4Q A;  1LYK A;  4GED A;  1CMU A;  1H5K A;  5SX2 A;  5CIF A;  2XJ6 A;  1BES A;  2VCS A;  4JMT A;  1GWO A;  1AEO A;  2XIL A;  1CPF A;  2N18 A;  5SYH A;  1KXM A;  5SXQ A;  3FMU A;  1JDR A;  4NFG A;  3FM1 A;  2VO2 X;  1AA4 A;  1AEJ A;  4NVJ B;  1AEK A;  1AES A;  1CK6 A;  5SX0 A;  5SX1 A;  5ALA A;  1AEG A;  4H7A A;  5SXS A;  4JQN A;  3UW8 A;  1OAG A;  1CMT A;  1BGP A;  5ABO A;  4BLX A;  1H3J A;  5CIE A;  4USC A;  4JM5 A;  3VLJ A;  2CCA A;  3ZCG A;  1AC4 A;  3FKG A;  1MKR A;  5ABQ A;  2E3B A;  1APX A;  5SYX A;  5SYY A;  3M25 A;  1CCK A;  1LGA A;  4NVO B;  1CPE A;  4NVF A;  2JTI A;  7ATJ A;  5KQ2 A;  1ATJ A;  4NVD A;  4QYZ B;  4JPU A;  2YCG A;  1H5A A;  5KSF A;  2VKA A;  4ATJ A;  2AS1 A;  2CEP A;  4JMA A;  1ARU A;  4JB4 A;  6ATJ A;  2ATJ A;  2XI6 A;  5CJH A;  1LY8 A;  1GW2 A;  4XV8 A;  4NVM B;  1ML2 A;  5FNB A;  5KQH A;  2XJ8 A;  5SX3 A;  5L02 A;  1CMQ A;  4BM3 A;  1QO4 A;  1GZB A;  2B10 A;  3VLL A;  3EXB A;  1H5J A;  1KZM A;  4C51 A;  5D6M A;  1IYN A;  3M5Q A;  1B80 A;  1CCC A;  3RIW A;  2XJ5 A;  5JHZ A;  2YLJ A;  2GGN X;  1MKQ A;  1H5D A;  2Y5A A;  4FCN A;  1LLP A;  2GB8 A;  3R98 A;  4C50 A;  5SXR A;  2GHK X;  3UT2 A;  1A2G A;  3HDL A;  4JMS A;  5SX7 A;  2PCB A;  3M2F A;  4A71 A;  2RBY X;  3CCP A;  1AC8 A;  5SXT A;  3M2E A;  2VNX X;  1ZBY A;  5CIB A;  4JZA A;  2RBT X;  2W23 A;  4CZR A;  1STQ A;  5EJX A;  4NVI B;  2XIH A;  4JMW A;  5AOG A;  4BLZ A;  3M2B A;  5CIG A;  1EBE A;  1FHF A;  1AEV A;  1DJ1 A;  1S6V A;  1YZP A;  4CZN A;  4BM2 A;  1W4Y A;  2RBV X;  5FNE A;  2EUP A;  4BLN A;  4JPL A;  4JM6 A;  2E39 A;  4XV6 A;  4FDQ A;  1CPG A;  1LYC A;  1YZR A;  2EUQ A;  4BM1 A;  4CZQ A;  2RC0 X;  3Q3U A;  1PA2 A;  2ICV A;  3VLK A;  4JMZ A;  5SXW A;  3X16 A;  1MK8 A;  4A5G A;  4A6Z A;  1GZA A;  5AL9 A;  1AEN A;  3M2I A;  3CCX A;  1BEK A;  2GHH X;  1RYC A;  2EUT A;  1CCI A;  1S73 A;  4JPT A;  5SYW A;  3R99 A;  4BM4 A;  5H9E B;  2RBZ X;  4BLY A;  2VCN A;  1H5H A;  1U2J A;  1DSE A;  2ANZ A;  1V0H X;  4JN0 A;  3WA8 A;  1H57 A;  1AEH A;  1CYF A;  2B11 A;  1H5C A;  1GWT A;  5SYI A;  1GWU A;  1JCI A;  1SDQ A;  2CYP A;  2PCC A;  3FM6 A;  1SJ2 A;  5CCP A;  1QPA A;  3ATJ A;  3M26 A;  5JHX A;  1DSG A;  3M2C A;  5SW5 A;  1CMP A;  3VLM A;  3M8M A;  5SW4 A;  2GHC X;  3RRW A;  1H5L A;  5SYU A;  2AS3 A;  1KXN A;  4OQ7 A;  2GHE X;  5EJT A;  2X07 A;  2AS6 A;  5CIC A;  1GX2 A;  1B82 A;  3M2H A;  2CCP A;  1AEQ A;  1U74 A;  3M28 A;  4BLK A;  1AEM A;  5CIH A;  3M29 A;  1CCJ A;  2VCF X;  1UB2 A;  3VLH A;  1U75 A;  1CPD A;  2CCD A;  3WXO A;  1DS4 A;  2Y6A A;  1SOG A;  1Z53 A;  5SYV A;  1DSO A;  3M2G A;  2X08 A;  1H5G A;  2RBX X;  3E2N A;  1MN1 A;  2AQD A;  2AS2 A;  2V23 A;  2BOQ A;  4JM9 A;  1AET A;  5CID A;  5KQI A;  4NVE A;  1OAF A;  5H9F B;  1CCP A;  1ITK A;  2VNZ X;  1SCH A;  4JQJ A;  1SBM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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