1AWEA

Human sos1 pleckstrin homology (ph) domain, nmr, 20 structures
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
130
structure length
130
Chain Sequence
MNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains.
pubmed doi rcsb
molecule tags Signal transduction
source organism Homo sapiens
molecule keywords SOS1
total genus 17
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 1997-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1aweA00
4ZRKA 2P8VA 2MWNB 4KHAA 2W2XD 4MK0A 2DKPA 2HE7A 2YT0A 2GJYA 2Z0PA 4GMXB 2DA0A 2VRWB 4IOYX 2K2UA 4A6FB 3SUZA 3HW2B 1FB8A 1I2HA 3PVUA 1FGZA 1XD4A 4HB3B 2DKQA 1EGXA 3FSSA 3PSCA 5L81A 2QKLA 3X23A 3VOQA 4K17A 5JHHA 4A6HA 4EMOA 5DIFB 4HAYB 5JP4A 1OMWA 3ODXA 2J0JA 2Y8GA 2RLOA 2LYDA 2D11A 2N0YA 1TQZA 2MDXA 2LOZA 1MKEA 1WVHA 2P0FA 5J3TA 1WGUA 1KI1B 1K5DB 3GYPA 2G35A 4D0NB 1MIXA 2D10A 3KZ1A 4ZRIA 4GMVA 4CHJA 3TW1A 2D2QA 3TCAA 1FHXA 1FAOA 1W1HA 1X1FA 1UNQA 1DDWA 1XR0B 3ML4A 3U8ZA 1RJ2A 4DX90 2D9XA 3BINA 4Z2MB 2R0DA 3GYOA 1V89A 5JHGA 1ZM0A 4KVGB 1EF1A 3ULBA 4K81A 2Z0OA 5CLLB 4CYEA 4HAZB 1QQGA 3KSYA 2LKOA 2DHJA 4F7HA 1GC7A 1WJMA 5LOPB 3ZVRA 5DH9B 4TKNA 1OY2A 2UVMA 2LULA 2COCA 4K2OA 1UNRA 1H4RA 4GZUA 1XX0A 1BTKA 2ROVA 1BTNA 2JP2A 2J0MA 1LB1A 3AJ4A 5KQ1A 1B55A 2GS0A 2FJLA 4K2PA 1MAIA 1LW3A 4MT7A 2GCLA 4DXAB 1WJ1A 3SNHA 1MK9B 2NMBA 3D8DA 3A8QA 2DYNA 3QWMA 2LG1A 4L6EA 2UZRA 2DFKA 1PLSA 2CY5A 5C5BA 3F5RA 4HB0B 4CHMA 2DHKA 4YL8A 2YT1A 2P0DA 1V5MA 2Y8FA 1IRSA 4HDQA 1AWEA 3QBVB 3V5WA 2XQNM 2MFQA 3ZDTA 1DBHA 2ZPYA 4B6HA 2UZSA 3U7DA 2ELAA 4NY0A 2DN6A 5D27A 4PQ0A 3D8FA 1ZVRA 3WA0A 1TXDA 1FGYA 1BAKA 3T06A 5C79A 3PP2A 1SGHA 1DDVA 4Z2NA 5FI1A 5EFXA 1E5WA 2RNRB 4HAVB 3PG7A 1UEFA 3HQCA 2ROZB 3ODWA 1X05A 2CODA 4F7UP 3DXCA 2ELBA 5JLJB 1M7RA 2COAA 1U27A 2CRFA 4H8SA 3TVVA 2AL6A 1P3RA 4BBKA 1PFJA 2X18A 2YS1A 1W1DA 1AQCA 1MIZB 4A6KA 1Y19B 2KCJA 4PNKA 3MDBC 3SYXA 1EVHA 2AEHA 3MPXA 2H7EA 1NTYA 1WG7A 3ODOA 3AU4A 4A6FA 3F0WA 1X1GA 1Y5OA 2ADZA 1PMSA 5DHAB 4IFSA 1WGQA 5J3QA 2LOXA 1XKEA 2YS3A 5DI9B 2K2JA 2OQBA 5KQ4A 3RCPA 1H10A 3A8PA 2L2IA 2M38A 4HATB 2IFSA 2K00A 2J0KA 1OQNA 1MPHA 3IVFA 1FOEA 1X11A 4WVFB 1KZGA 1QC6A 1DYNA 1X86A 3ULCA 5HE3A 3KRWA 4IAPA 1KZ7A 2EMSA 3TFMA 3DXEA 2L1CA 1EAZA 2DYQA 3PVWA 1TJ6A 2M14A 2H7DA 2Y7BA 2IYBA 1K5GB 1U2BA 4KHOA 1U29A 5HE1A 2DTCA 4HB4B 3LJUX 1V61A 1GG3A 4KHBB 2KGXB 3M1IB 2RSGA 2I1JA 3VIAA 5D3VA 1U5EA 2VSZA 4C0AA 4ZRJA 4YONA 2V76A 2PZ1A 2COFA 1MK7B 5FI0A 3QIJA 3WYFB 2D9ZA 2GCJA 1NTVA 4TYZA 2EJ8A 3D8EA 3P6AA 2J59M 5C16A 3HK0A 4DBBA 2BCJA 1W1GA 2NZ8B 2RGNB 1NI2A 1U5GA 3NSUA 2DX5A 2W2WA 4EJNA 1WI1A 3P7ZA 3OANA 1FHOA 1SHCA 1U5DA 1UPRA 5D3XA 1DROA 1DDMA 4GN1A 3PVLA 1V5UA 3CIKA 3PEGA 2Z0QA 3A98B 5CLQB 2EC1A 4WJ7A 2HTHB 4HAUB 2DX1A 2D9VA 1U5FA 1J19A 3N7CA 1Z87A 3SV1A 2QKMA 5C6RA 3SO6A 2DLWA 1FHWA 5HE0A 2P0HA 3G9WA 4MY6A 4P7IA 2YRYA 4XWXA 2OTXA 5D3YA 4GXBA 4Y94A 2CAYA 2Q13A 5GOWB 1XODA 5C5BB 1BWNA 2D9WA 3FM8C 1RRPB 1M7EA 3O96A 2E2XA 4WSFA 5DHFB 3UZTA 4HB2B 4HAXB 1GC6A 3BJIA 4KAXB 4DX8A 1ZSQA 1P6SA 3FEHA 1I7AA 2I5FA 2YSZA 3CXBB 3AU5A 2W2XC 3TO1A 5KCVA 4GPTB 2YVCA 5LONB 5J3YA 1J0WA 3KY9A 1ISNA 1N3HA 3KRXA 1V5PA 1ZC3B 2I1KA 2N23A 2EMTA 2D9YA 2VKIA 2RUKB 1Q67A 3PZDA 4F7GA 2CY4A 2YF0A 1NU2A 4HDOA 5HE2A 2KUPA 1P5TA 2RVBB 2D4QA 2R09A 2MKRA 5D3WA 1UPQA 4HHVA 2YS5A 1XCGA 4EKUA 2DHIA 4NSWA 1UNPA 4A5KA 1V88A 2I5CA 1ZC4B 4HAWB 3DXDA
chains in the Genus database with same CATH superfamily
4ZRKA 2P8VA 2MWNB 2Z14A 4KHAA 2W2XD 4MK0A 2DKPA 3NWDA 2HE7A 2YT0A 2GJYA 2Z0PA 4GMXB 2DA0A 2VRWB 1ZYIA 4IOYX 2K2UA 4A6FB 3SUZA 3HW2B 1FB8A 1I2HA 3PVUA 1FGZA 5IRSA 1XD4A 4HB3B 2DKQA 1EGXA 3A58A 3FSSA 3PSCA 5L81A 2QKLA 3X23A 3VOQA 4K17A 5JHHA 4A6HA 4EMOA 5DIFB 4HAYB 5JP4A 1OMWA 3ODXA 4GNKB 2J0JA 2Y8GA 2RLOA 2LYDA 2D11A 2N0YA 1TQZA 2MDXA 2LOZA 1MKEA 1WVHA 2P0FA 5J3TA 1WGUA 1KI1B 1K5DB 3GYPA 2G35A 4D0NB 1MIXA 2D10A 3KZ1A 4ZRIA 4GMVA 4CHJA 3TW1A 2D2QA 3TCAA 1FHXA 1FAOA 1W1HA 1X1FA 1UNQA 1DDWA 1XR0B 3ML4A 3U8ZA 1RJ2A 4DX90 2D9XA 3BINA 4Z2MB 2R0DA 3GYOA 1V89A 5JHGA 1ZM0A 3U12A 4KVGB 1EF1A 3ULBA 4K81A 2Z0OA 5CLLB 4CYEA 4HAZB 1QQGA 3KSYA 2LKOA 2DHJA 4F7HA 1GC7A 1WJMA 5LOPB 2KIEA 3ZVRA 5DH9B 4TKNA 1OY2A 2UVMA 2LULA 2COCA 4K2OA 1UNRA 1H4RA 4GZUA 1XX0A 1BTKA 2ROVA 1BTNA 2JP2A 2J0MA 1LB1A 3AJ4A 5KQ1A 1B55A 4QXAB 2GS0A 2FJLA 4K2PA 1MAIA 1LW3A 4MT7A 2GCLA 4DXAB 1WJ1A 3SNHA 1MK9B 2NMBA 3D8DA 3A8QA 3NWAA 2DYNA 3QWMA 2KR0A 2LG1A 2FJUB 4L6EA 5I2MA 2UZRA 2YT2A 2DFKA 1PLSA 2CY5A 3DCXA 5C5BA 3F5RA 4HB0B 4CHMA 2DHKA 4YL8A 2K8EA 2YT1A 2P0DA 2RRFA 1V5MA 2Y8FA 1IRSA 4HDQA 1AWEA 3QBVB 3V5WA 4QJ4B 2XQNM 2MFQA 3ZDTA 1DBHA 2ZPYA 4B6HA 2UZSA 2KIGA 3U7DA 2ELAA 4NY0A 5LG4B 2DN6A 5D27A 4PQ0A 3D8FA 1ZVRA 3WA0A 1TXDA 1FGYA 1BAKA 3T06A 5C79A 3PP2A 1SGHA 1DDVA 4Z2NA 5FI1A 5EFXA 1E5WA 2RNRB 4HAVB 3PG7A 1UEFA 3HQCA 2ROZB 3ODWA 1X05A 2CODA 4F7UP 2Z4DA 3DXCA 2ELBA 5JLJB 1M7RA 2COAA 1U27A 2CRFA 4DIXA 4H8SA 3TVVA 2AL6A 1P3RA 4BBKA 1PFJA 4L1RA 4HSIA 2X18A 2YS1A 1W1DA 1AQCA 2NBVA 1MIZB 4A6KA 1Y19B 2KCJA 4PNKA 3MDBC 3SYXA 1EVHA 2AEHA 3MPXA 2H7EA 1NTYA 1WG7A 3ODOA 3AU4A 4A6FA 3F0WA 1X1GA 1Y5OA 2ADZA 1PMSA 5DHAB 3HSAA 4IFSA 1WGQA 5J3QA 2LOXA 1XKEA 2YS3A 5DI9B 2K2JA 2OQBA 5KQ4A 3RCPA 1H10A 3A8PA 2L2IA 2M38A 4HATB 2IFSA 2K00A 2J0KA 1OQNA 1MPHA 3IVFA 1FOEA 1X11A 4WVFB 1KZGA 5I2SA 1QC6A 1DYNA 1X86A 3ULCA 5HE3A 3KRWA 4IAPA 1KZ7A 2EMSA 3TFMA 3DXEA 2L1CA 4CSQA 1EAZA 4OT1A 1MI1A 2DYQA 3PVWA 1TJ6A 2M14A 2H7DA 2Y7BA 2IYBA 1K5GB 1U2BA 4KHOA 1U29A 5HE1A 2DTCA 4HB4B 3LJUX 1V61A 1GG3A 2Z59A 4QJ3B 4KHBB 2KGXB 3M1IB 2RSGA 2I1JA 2ZKMX 3VIAA 5D3VA 1U5EA 2VSZA 4C0AA 4ZRJA 4YONA 5M4YB 2V76A 2PZ1A 2COFA 1MK7B 5FI0A 3QIJA 3WYFB 2D9ZA 2GCJA 1NTVA 2R2YA 4TYZA 4QJ5B 2EJ8A 3D8EA 3P6AA 2J59M 2GUMA 5C16A 3HK0A 4DBBA 2BCJA 1W1GA 2NZ8B 2RGNB 1NI2A 1U5GA 2DX5A 2W2WA 3NSUA 3NW8A 4EJNA 1WI1A 3P7ZA 3OANA 1FHOA 1SHCA 1U5DA 1UPRA 5D3XA 1DROA 1DDMA 4GN1A 3PVLA 1V5UA 3CIKA 3PEGA 2Z0QA 3A98B 5CLQB 2EC1A 4WJ7A 2HTHB 4HAUB 2DX1A 2D9VA 1U5FA 1J19A 3N7CA 1Z87A 3SV1A 2QKMA 5C6RA 3HIEA 3SO6A 2DLWA 1FHWA 5HE0A 2P0HA 3G9WA 4MY6A 4P7IA 2YRYA 4XWXA 2KUQA 2OTXA 5D3YA 4GXBA 4Y94A 2CAYA 2Q13A 5GOWB 1XODA 5C5BB 1BWNA 2D9WA 3FM8C 1RRPB 1M7EA 3O96A 2E2XA 4WSFA 5DHFB 3UZTA 4HB2B 4HAXB 2Z13A 1GC6A 1T77A 3BJIA 4KAXB 4OSNA 4KHBA 4DX8A 1ZSQA 1P6SA 3FEHA 1I7AA 2I5FA 2YSZA 3CXBB 3AU5A 2W2XC 3TO1A 2K49A 5KCVA 4GPTB 2YVCA 4D6WA 5LONB 5J3YA 1J0WA 3KY9A 1ISNA 1N3HA 3KRXA 1V5PA 1ZC3B 2I1KA 2N23A 2EMTA 2D9YA 2VKIA 3FVCA 2RUKB 1Q67A 3PZDA 4F7GA 2CY4A 4GOUA 2YF0A 1NU2A 4HDOA 5HE2A 2KUPA 3NWFA 3OHMB 1P5TA 2RVBB 3B77A 2D4QA 2R09A 2MKRA 5D3WA 1UPQA 4HHVA 2YS5A 1XCGA 4EKUA 2DHIA 4NSWA 1UNPA 4A5KA 1V88A 2I5CA 1ZC4B 4HAWB 3DXDA
chains in the Genus database with same CATH topology
4ZRKA 2P8VA 2MWNB 4KHAA 2W2XD 4MK0A 2DKPA 2HE7A 2YT0A 2GJYA 2Z0PA 4GMXB 2DA0A 2VRWB 4IOYX 2K2UA 4A6FB 3SUZA 3HW2B 1FB8A 1I2HA 3PVUA 1FGZA 1XD4A 4HB3B 2DKQA 1EGXA 3FSSA 3PSCA 5L81A 2QKLA 3X23A 3VOQA 4K17A 5JHHA 4A6HA 4EMOA 5DIFB 4HAYB 5JP4A 1OMWA 3ODXA 2J0JA 2Y8GA 2RLOA 2LYDA 2D11A 2N0YA 1TQZA 2MDXA 2LOZA 1MKEA 1WVHA 2P0FA 5J3TA 1WGUA 1KI1B 1K5DB 3GYPA 2G35A 4D0NB 1MIXA 2D10A 3KZ1A 4ZRIA 4GMVA 4CHJA 3TW1A 2D2QA 3TCAA 1FHXA 1FAOA 1W1HA 1X1FA 1UNQA 1DDWA 1XR0B 3ML4A 3U8ZA 1RJ2A 4DX90 2D9XA 3BINA 4Z2MB 2R0DA 3GYOA 1V89A 5JHGA 1ZM0A 4KVGB 1EF1A 3ULBA 4K81A 2Z0OA 5CLLB 4CYEA 4HAZB 1QQGA 3KSYA 2LKOA 2DHJA 4F7HA 1GC7A 1WJMA 5LOPB 3ZVRA 5DH9B 4TKNA 1OY2A 2UVMA 2LULA 2COCA 4K2OA 1UNRA 1H4RA 4GZUA 1XX0A 1BTKA 2ROVA 1BTNA 2JP2A 2J0MA 1LB1A 3AJ4A 5KQ1A 1B55A 2GS0A 2FJLA 4K2PA 1MAIA 1LW3A 4MT7A 2GCLA 4DXAB 1WJ1A 3SNHA 1MK9B 2NMBA 3D8DA 3A8QA 2DYNA 3QWMA 2LG1A 4L6EA 2UZRA 2DFKA 1PLSA 2CY5A 5C5BA 3F5RA 4HB0B 4CHMA 2DHKA 4YL8A 2YT1A 2P0DA 1V5MA 2Y8FA 1IRSA 4HDQA 1AWEA 3QBVB 3V5WA 2XQNM 2MFQA 3ZDTA 1DBHA 2ZPYA 4B6HA 2UZSA 3U7DA 2ELAA 4NY0A 2DN6A 5D27A 4PQ0A 3D8FA 1ZVRA 3WA0A 1TXDA 1FGYA 1BAKA 3T06A 5C79A 3PP2A 1SGHA 1DDVA 4Z2NA 5FI1A 5EFXA 1E5WA 2RNRB 4HAVB 3PG7A 1UEFA 3HQCA 2ROZB 3ODWA 1X05A 2CODA 4F7UP 3DXCA 2ELBA 5JLJB 1M7RA 2COAA 1U27A 2CRFA 4H8SA 3TVVA 2AL6A 1P3RA 4BBKA 1PFJA 2X18A 2YS1A 1W1DA 1AQCA 1MIZB 4A6KA 1Y19B 2KCJA 4PNKA 3MDBC 3SYXA 1EVHA 2AEHA 3MPXA 2H7EA 1NTYA 1WG7A 3ODOA 3AU4A 4A6FA 3F0WA 1X1GA 1Y5OA 2ADZA 1PMSA 5DHAB 4IFSA 1WGQA 5J3QA 2LOXA 1XKEA 2YS3A 5DI9B 2K2JA 2OQBA 5KQ4A 3RCPA 1H10A 3A8PA 2L2IA 2M38A 4HATB 2IFSA 2K00A 2J0KA 1OQNA 1MPHA 3IVFA 1FOEA 1X11A 4WVFB 1KZGA 1QC6A 1DYNA 1X86A 3ULCA 5HE3A 3KRWA 4IAPA 1KZ7A 2EMSA 3TFMA 3DXEA 2L1CA 1EAZA 2DYQA 3PVWA 1TJ6A 2M14A 2H7DA 2Y7BA 2IYBA 1K5GB 1U2BA 4KHOA 1U29A 5HE1A 2DTCA 4HB4B 3LJUX 1V61A 1GG3A 4KHBB 2KGXB 3M1IB 2RSGA 2I1JA 3VIAA 5D3VA 1U5EA 2VSZA 4C0AA 4ZRJA 4YONA 2V76A 2PZ1A 2COFA 1MK7B 5FI0A 3QIJA 3WYFB 2D9ZA 2GCJA 1NTVA 4TYZA 2EJ8A 3D8EA 3P6AA 2J59M 5C16A 3HK0A 4DBBA 2BCJA 1W1GA 2NZ8B 2RGNB 1NI2A 1U5GA 3NSUA 2DX5A 2W2WA 4EJNA 1WI1A 3P7ZA 3OANA 1FHOA 1SHCA 1U5DA 1UPRA 5D3XA 1DROA 1DDMA 4GN1A 3PVLA 1V5UA 3CIKA 3PEGA 2Z0QA 3A98B 5CLQB 2EC1A 4WJ7A 2HTHB 4HAUB 2DX1A 2D9VA 1U5FA 1J19A 3N7CA 1Z87A 3SV1A 2QKMA 5C6RA 3SO6A 2DLWA 1FHWA 5HE0A 2P0HA 3G9WA 4MY6A 4P7IA 2YRYA 4XWXA 2OTXA 5D3YA 4GXBA 4Y94A 2CAYA 2Q13A 5GOWB 1XODA 5C5BB 1BWNA 2D9WA 3FM8C 1RRPB 1M7EA 3O96A 2E2XA 4WSFA 5DHFB 3UZTA 4HB2B 4HAXB 1GC6A 3BJIA 4KAXB 4DX8A 1ZSQA 1P6SA 3FEHA 1I7AA 2I5FA 2YSZA 3CXBB 3AU5A 2W2XC 3TO1A 5KCVA 4GPTB 2YVCA 5LONB 5J3YA 1J0WA 3KY9A 1ISNA 1N3HA 3KRXA 1V5PA 1ZC3B 2I1KA 2N23A 2EMTA 2D9YA 2VKIA 2RUKB 1Q67A 3PZDA 4F7GA 2CY4A 2YF0A 1NU2A 4HDOA 5HE2A 2KUPA 1P5TA 2RVBB 2D4QA 2R09A 2MKRA 5D3WA 1UPQA 4HHVA 2YS5A 1XCGA 4EKUA 2DHIA 4NSWA 1UNPA 4A5KA 1V88A 2I5CA 1ZC4B 4HAWB 3DXDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZRK A;  2P8V A;  2MWN B;  4KHA A;  2W2X D;  4MK0 A;  2DKP A;  2HE7 A;  2YT0 A;  2GJY A;  2Z0P A;  4GMX B;  2DA0 A;  2VRW B;  4IOY X;  2K2U A;  4A6F B;  3SUZ A;  3HW2 B;  1FB8 A;  1I2H A;  3PVU A;  1FGZ A;  1XD4 A;  4HB3 B;  2DKQ A;  1EGX A;  3FSS A;  3PSC A;  5L81 A;  2QKL A;  3X23 A;  3VOQ A;  4K17 A;  5JHH A;  4A6H A;  4EMO A;  5DIF B;  4HAY B;  5JP4 A;  1OMW A;  3ODX A;  2J0J A;  2Y8G A;  2RLO A;  2LYD A;  2D11 A;  2N0Y A;  1TQZ A;  2MDX A;  2LOZ A;  1MKE A;  1WVH A;  2P0F A;  5J3T A;  1WGU A;  1KI1 B;  1K5D B;  3GYP A;  2G35 A;  4D0N B;  1MIX A;  2D10 A;  3KZ1 A;  4ZRI A;  4GMV A;  4CHJ A;  3TW1 A;  2D2Q A;  3TCA A;  1FHX A;  1FAO A;  1W1H A;  1X1F A;  1UNQ A;  1DDW A;  1XR0 B;  3ML4 A;  3U8Z A;  1RJ2 A;  4DX9 0;  2D9X A;  3BIN A;  4Z2M B;  2R0D A;  3GYO A;  1V89 A;  5JHG A;  1ZM0 A;  4KVG B;  1EF1 A;  3ULB A;  4K81 A;  2Z0O A;  5CLL B;  4CYE A;  4HAZ B;  1QQG A;  3KSY A;  2LKO A;  2DHJ A;  4F7H A;  1GC7 A;  1WJM A;  5LOP B;  3ZVR A;  5DH9 B;  4TKN A;  1OY2 A;  2UVM A;  2LUL A;  2COC A;  4K2O A;  1UNR A;  1H4R A;  4GZU A;  1XX0 A;  1BTK A;  2ROV A;  1BTN A;  2JP2 A;  2J0M A;  1LB1 A;  3AJ4 A;  5KQ1 A;  1B55 A;  2GS0 A;  2FJL A;  4K2P A;  1MAI A;  1LW3 A;  4MT7 A;  2GCL A;  4DXA B;  1WJ1 A;  3SNH A;  1MK9 B;  2NMB A;  3D8D A;  3A8Q A;  2DYN A;  3QWM A;  2LG1 A;  4L6E A;  2UZR A;  2DFK A;  1PLS A;  2CY5 A;  5C5B A;  3F5R A;  4HB0 B;  4CHM A;  2DHK A;  4YL8 A;  2YT1 A;  2P0D A;  1V5M A;  2Y8F A;  1IRS A;  4HDQ A;  1AWE A;  3QBV B;  3V5W A;  2XQN M;  2MFQ A;  3ZDT A;  1DBH A;  2ZPY A;  4B6H A;  2UZS A;  3U7D A;  2ELA A;  4NY0 A;  2DN6 A;  5D27 A;  4PQ0 A;  3D8F A;  1ZVR A;  3WA0 A;  1TXD A;  1FGY A;  1BAK A;  3T06 A;  5C79 A;  3PP2 A;  1SGH A;  1DDV A;  4Z2N A;  5FI1 A;  5EFX A;  1E5W A;  2RNR B;  4HAV B;  3PG7 A;  1UEF A;  3HQC A;  2ROZ B;  3ODW A;  1X05 A;  2COD A;  4F7U P;  3DXC A;  2ELB A;  5JLJ B;  1M7R A;  2COA A;  1U27 A;  2CRF A;  4H8S A;  3TVV A;  2AL6 A;  1P3R A;  4BBK A;  1PFJ A;  2X18 A;  2YS1 A;  1W1D A;  1AQC A;  1MIZ B;  4A6K A;  1Y19 B;  2KCJ A;  4PNK A;  3MDB C;  3SYX A;  1EVH A;  2AEH A;  3MPX A;  2H7E A;  1NTY A;  1WG7 A;  3ODO A;  3AU4 A;  4A6F A;  3F0W A;  1X1G A;  1Y5O A;  2ADZ A;  1PMS A;  5DHA B;  4IFS A;  1WGQ A;  5J3Q A;  2LOX A;  1XKE A;  2YS3 A;  5DI9 B;  2K2J A;  2OQB A;  5KQ4 A;  3RCP A;  1H10 A;  3A8P A;  2L2I A;  2M38 A;  4HAT B;  2IFS A;  2K00 A;  2J0K A;  1OQN A;  1MPH A;  3IVF A;  1FOE A;  1X11 A;  4WVF B;  1KZG A;  1QC6 A;  1DYN A;  1X86 A;  3ULC A;  5HE3 A;  3KRW A;  4IAP A;  1KZ7 A;  2EMS A;  3TFM A;  3DXE A;  2L1C A;  1EAZ A;  2DYQ A;  3PVW A;  1TJ6 A;  2M14 A;  2H7D A;  2Y7B A;  2IYB A;  1K5G B;  1U2B A;  4KHO A;  1U29 A;  5HE1 A;  2DTC A;  4HB4 B;  3LJU X;  1V61 A;  1GG3 A;  4KHB B;  2KGX B;  3M1I B;  2RSG A;  2I1J A;  3VIA A;  5D3V A;  1U5E A;  2VSZ A;  4C0A A;  4ZRJ A;  4YON A;  2V76 A;  2PZ1 A;  2COF A;  1MK7 B;  5FI0 A;  3QIJ A;  3WYF B;  2D9Z A;  2GCJ A;  1NTV A;  4TYZ A;  2EJ8 A;  3D8E A;  3P6A A;  2J59 M;  5C16 A;  3HK0 A;  4DBB A;  2BCJ A;  1W1G A;  2NZ8 B;  2RGN B;  1NI2 A;  1U5G A;  3NSU A;  2DX5 A;  2W2W A;  4EJN A;  1WI1 A;  3P7Z A;  3OAN A;  1FHO A;  1SHC A;  1U5D A;  1UPR A;  5D3X A;  1DRO A;  1DDM A;  4GN1 A;  3PVL A;  1V5U A;  3CIK A;  3PEG A;  2Z0Q A;  3A98 B;  5CLQ B;  2EC1 A;  4WJ7 A;  2HTH B;  4HAU B;  2DX1 A;  2D9V A;  1U5F A;  1J19 A;  3N7C A;  1Z87 A;  3SV1 A;  2QKM A;  5C6R A;  3SO6 A;  2DLW A;  1FHW A;  5HE0 A;  2P0H A;  3G9W A;  4MY6 A;  4P7I A;  2YRY A;  4XWX A;  2OTX A;  5D3Y A;  4GXB A;  4Y94 A;  2CAY A;  2Q13 A;  5GOW B;  1XOD A;  5C5B B;  1BWN A;  2D9W A;  3FM8 C;  1RRP B;  1M7E A;  3O96 A;  2E2X A;  4WSF A;  5DHF B;  3UZT A;  4HB2 B;  4HAX B;  1GC6 A;  3BJI A;  4KAX B;  4DX8 A;  1ZSQ A;  1P6S A;  3FEH A;  1I7A A;  2I5F A;  2YSZ A;  3CXB B;  3AU5 A;  2W2X C;  3TO1 A;  5KCV A;  4GPT B;  2YVC A;  5LON B;  5J3Y A;  1J0W A;  3KY9 A;  1ISN A;  1N3H A;  3KRX A;  1V5P A;  1ZC3 B;  2I1K A;  2N23 A;  2EMT A;  2D9Y A;  2VKI A;  2RUK B;  1Q67 A;  3PZD A;  4F7G A;  2CY4 A;  2YF0 A;  1NU2 A;  4HDO A;  5HE2 A;  2KUP A;  1P5T A;  2RVB B;  2D4Q A;  2R09 A;  2MKR A;  5D3W A;  1UPQ A;  4HHV A;  2YS5 A;  1XCG A;  4EKU A;  2DHI A;  4NSW A;  1UNP A;  4A5K A;  1V88 A;  2I5C A;  1ZC4 B;  4HAW B;  3DXD A; 
#chains in the Genus database with same CATH topology
 4ZRK A;  2P8V A;  2MWN B;  2Z14 A;  4KHA A;  2W2X D;  4MK0 A;  2DKP A;  3NWD A;  2HE7 A;  2YT0 A;  2GJY A;  2Z0P A;  4GMX B;  2DA0 A;  2VRW B;  1ZYI A;  4IOY X;  2K2U A;  4A6F B;  3SUZ A;  3HW2 B;  1FB8 A;  1I2H A;  3PVU A;  1FGZ A;  5IRS A;  1XD4 A;  4HB3 B;  2DKQ A;  1EGX A;  3A58 A;  3FSS A;  3PSC A;  5L81 A;  2QKL A;  3X23 A;  3VOQ A;  4K17 A;  5JHH A;  4A6H A;  4EMO A;  5DIF B;  4HAY B;  5JP4 A;  1OMW A;  3ODX A;  4GNK B;  2J0J A;  2Y8G A;  2RLO A;  2LYD A;  2D11 A;  2N0Y A;  1TQZ A;  2MDX A;  2LOZ A;  1MKE A;  1WVH A;  2P0F A;  5J3T A;  1WGU A;  1KI1 B;  1K5D B;  3GYP A;  2G35 A;  4D0N B;  1MIX A;  2D10 A;  3KZ1 A;  4ZRI A;  4GMV A;  4CHJ A;  3TW1 A;  2D2Q A;  3TCA A;  1FHX A;  1FAO A;  1W1H A;  1X1F A;  1UNQ A;  1DDW A;  1XR0 B;  3ML4 A;  3U8Z A;  1RJ2 A;  4DX9 0;  2D9X A;  3BIN A;  4Z2M B;  2R0D A;  3GYO A;  1V89 A;  5JHG A;  1ZM0 A;  3U12 A;  4KVG B;  1EF1 A;  3ULB A;  4K81 A;  2Z0O A;  5CLL B;  4CYE A;  4HAZ B;  1QQG A;  3KSY A;  2LKO A;  2DHJ A;  4F7H A;  1GC7 A;  1WJM A;  5LOP B;  2KIE A;  3ZVR A;  5DH9 B;  4TKN A;  1OY2 A;  2UVM A;  2LUL A;  2COC A;  4K2O A;  1UNR A;  1H4R A;  4GZU A;  1XX0 A;  1BTK A;  2ROV A;  1BTN A;  2JP2 A;  2J0M A;  1LB1 A;  3AJ4 A;  5KQ1 A;  1B55 A;  4QXA B;  2GS0 A;  2FJL A;  4K2P A;  1MAI A;  1LW3 A;  4MT7 A;  2GCL A;  4DXA B;  1WJ1 A;  3SNH A;  1MK9 B;  2NMB A;  3D8D A;  3A8Q A;  3NWA A;  2DYN A;  3QWM A;  2KR0 A;  2LG1 A;  2FJU B;  4L6E A;  5I2M A;  2UZR A;  2YT2 A;  2DFK A;  1PLS A;  2CY5 A;  3DCX A;  5C5B A;  3F5R A;  4HB0 B;  4CHM A;  2DHK A;  4YL8 A;  2K8E A;  2YT1 A;  2P0D A;  2RRF A;  1V5M A;  2Y8F A;  1IRS A;  4HDQ A;  1AWE A;  3QBV B;  3V5W A;  4QJ4 B;  2XQN M;  2MFQ A;  3ZDT A;  1DBH A;  2ZPY A;  4B6H A;  2UZS A;  2KIG A;  3U7D A;  2ELA A;  4NY0 A;  5LG4 B;  2DN6 A;  5D27 A;  4PQ0 A;  3D8F A;  1ZVR A;  3WA0 A;  1TXD A;  1FGY A;  1BAK A;  3T06 A;  5C79 A;  3PP2 A;  1SGH A;  1DDV A;  4Z2N A;  5FI1 A;  5EFX A;  1E5W A;  2RNR B;  4HAV B;  3PG7 A;  1UEF A;  3HQC A;  2ROZ B;  3ODW A;  1X05 A;  2COD A;  4F7U P;  2Z4D A;  3DXC A;  2ELB A;  5JLJ B;  1M7R A;  2COA A;  1U27 A;  2CRF A;  4DIX A;  4H8S A;  3TVV A;  2AL6 A;  1P3R A;  4BBK A;  1PFJ A;  4L1R A;  4HSI A;  2X18 A;  2YS1 A;  1W1D A;  1AQC A;  2NBV A;  1MIZ B;  4A6K A;  1Y19 B;  2KCJ A;  4PNK A;  3MDB C;  3SYX A;  1EVH A;  2AEH A;  3MPX A;  2H7E A;  1NTY A;  1WG7 A;  3ODO A;  3AU4 A;  4A6F A;  3F0W A;  1X1G A;  1Y5O A;  2ADZ A;  1PMS A;  5DHA B;  3HSA A;  4IFS A;  1WGQ A;  5J3Q A;  2LOX A;  1XKE A;  2YS3 A;  5DI9 B;  2K2J A;  2OQB A;  5KQ4 A;  3RCP A;  1H10 A;  3A8P A;  2L2I A;  2M38 A;  4HAT B;  2IFS A;  2K00 A;  2J0K A;  1OQN A;  1MPH A;  3IVF A;  1FOE A;  1X11 A;  4WVF B;  1KZG A;  5I2S A;  1QC6 A;  1DYN A;  1X86 A;  3ULC A;  5HE3 A;  3KRW A;  4IAP A;  1KZ7 A;  2EMS A;  3TFM A;  3DXE A;  2L1C A;  4CSQ A;  1EAZ A;  4OT1 A;  1MI1 A;  2DYQ A;  3PVW A;  1TJ6 A;  2M14 A;  2H7D A;  2Y7B A;  2IYB A;  1K5G B;  1U2B A;  4KHO A;  1U29 A;  5HE1 A;  2DTC A;  4HB4 B;  3LJU X;  1V61 A;  1GG3 A;  2Z59 A;  4QJ3 B;  4KHB B;  2KGX B;  3M1I B;  2RSG A;  2I1J A;  2ZKM X;  3VIA A;  5D3V A;  1U5E A;  2VSZ A;  4C0A A;  4ZRJ A;  4YON A;  5M4Y B;  2V76 A;  2PZ1 A;  2COF A;  1MK7 B;  5FI0 A;  3QIJ A;  3WYF B;  2D9Z A;  2GCJ A;  1NTV A;  2R2Y A;  4TYZ A;  4QJ5 B;  2EJ8 A;  3D8E A;  3P6A A;  2J59 M;  2GUM A;  5C16 A;  3HK0 A;  4DBB A;  2BCJ A;  1W1G A;  2NZ8 B;  2RGN B;  1NI2 A;  1U5G A;  2DX5 A;  2W2W A;  3NSU A;  3NW8 A;  4EJN A;  1WI1 A;  3P7Z A;  3OAN A;  1FHO A;  1SHC A;  1U5D A;  1UPR A;  5D3X A;  1DRO A;  1DDM A;  4GN1 A;  3PVL A;  1V5U A;  3CIK A;  3PEG A;  2Z0Q A;  3A98 B;  5CLQ B;  2EC1 A;  4WJ7 A;  2HTH B;  4HAU B;  2DX1 A;  2D9V A;  1U5F A;  1J19 A;  3N7C A;  1Z87 A;  3SV1 A;  2QKM A;  5C6R A;  3HIE A;  3SO6 A;  2DLW A;  1FHW A;  5HE0 A;  2P0H A;  3G9W A;  4MY6 A;  4P7I A;  2YRY A;  4XWX A;  2KUQ A;  2OTX A;  5D3Y A;  4GXB A;  4Y94 A;  2CAY A;  2Q13 A;  5GOW B;  1XOD A;  5C5B B;  1BWN A;  2D9W A;  3FM8 C;  1RRP B;  1M7E A;  3O96 A;  2E2X A;  4WSF A;  5DHF B;  3UZT A;  4HB2 B;  4HAX B;  2Z13 A;  1GC6 A;  1T77 A;  3BJI A;  4KAX B;  4OSN A;  4KHB A;  4DX8 A;  1ZSQ A;  1P6S A;  3FEH A;  1I7A A;  2I5F A;  2YSZ A;  3CXB B;  3AU5 A;  2W2X C;  3TO1 A;  2K49 A;  5KCV A;  4GPT B;  2YVC A;  4D6W A;  5LON B;  5J3Y A;  1J0W A;  3KY9 A;  1ISN A;  1N3H A;  3KRX A;  1V5P A;  1ZC3 B;  2I1K A;  2N23 A;  2EMT A;  2D9Y A;  2VKI A;  3FVC A;  2RUK B;  1Q67 A;  3PZD A;  4F7G A;  2CY4 A;  4GOU A;  2YF0 A;  1NU2 A;  4HDO A;  5HE2 A;  2KUP A;  3NWF A;  3OHM B;  1P5T A;  2RVB B;  3B77 A;  2D4Q A;  2R09 A;  2MKR A;  5D3W A;  1UPQ A;  4HHV A;  2YS5 A;  1XCG A;  4EKU A;  2DHI A;  4NSW A;  1UNP A;  4A5K A;  1V88 A;  2I5C A;  1ZC4 B;  4HAW B;  3DXD A; 
#chains in the Genus database with same CATH homology
 4ZRK A;  2P8V A;  2MWN B;  4KHA A;  2W2X D;  4MK0 A;  2DKP A;  2HE7 A;  2YT0 A;  2GJY A;  2Z0P A;  4GMX B;  2DA0 A;  2VRW B;  4IOY X;  2K2U A;  4A6F B;  3SUZ A;  3HW2 B;  1FB8 A;  1I2H A;  3PVU A;  1FGZ A;  1XD4 A;  4HB3 B;  2DKQ A;  1EGX A;  3FSS A;  3PSC A;  5L81 A;  2QKL A;  3X23 A;  3VOQ A;  4K17 A;  5JHH A;  4A6H A;  4EMO A;  5DIF B;  4HAY B;  5JP4 A;  1OMW A;  3ODX A;  2J0J A;  2Y8G A;  2RLO A;  2LYD A;  2D11 A;  2N0Y A;  1TQZ A;  2MDX A;  2LOZ A;  1MKE A;  1WVH A;  2P0F A;  5J3T A;  1WGU A;  1KI1 B;  1K5D B;  3GYP A;  2G35 A;  4D0N B;  1MIX A;  2D10 A;  3KZ1 A;  4ZRI A;  4GMV A;  4CHJ A;  3TW1 A;  2D2Q A;  3TCA A;  1FHX A;  1FAO A;  1W1H A;  1X1F A;  1UNQ A;  1DDW A;  1XR0 B;  3ML4 A;  3U8Z A;  1RJ2 A;  4DX9 0;  2D9X A;  3BIN A;  4Z2M B;  2R0D A;  3GYO A;  1V89 A;  5JHG A;  1ZM0 A;  4KVG B;  1EF1 A;  3ULB A;  4K81 A;  2Z0O A;  5CLL B;  4CYE A;  4HAZ B;  1QQG A;  3KSY A;  2LKO A;  2DHJ A;  4F7H A;  1GC7 A;  1WJM A;  5LOP B;  3ZVR A;  5DH9 B;  4TKN A;  1OY2 A;  2UVM A;  2LUL A;  2COC A;  4K2O A;  1UNR A;  1H4R A;  4GZU A;  1XX0 A;  1BTK A;  2ROV A;  1BTN A;  2JP2 A;  2J0M A;  1LB1 A;  3AJ4 A;  5KQ1 A;  1B55 A;  2GS0 A;  2FJL A;  4K2P A;  1MAI A;  1LW3 A;  4MT7 A;  2GCL A;  4DXA B;  1WJ1 A;  3SNH A;  1MK9 B;  2NMB A;  3D8D A;  3A8Q A;  2DYN A;  3QWM A;  2LG1 A;  4L6E A;  2UZR A;  2DFK A;  1PLS A;  2CY5 A;  5C5B A;  3F5R A;  4HB0 B;  4CHM A;  2DHK A;  4YL8 A;  2YT1 A;  2P0D A;  1V5M A;  2Y8F A;  1IRS A;  4HDQ A;  1AWE A;  3QBV B;  3V5W A;  2XQN M;  2MFQ A;  3ZDT A;  1DBH A;  2ZPY A;  4B6H A;  2UZS A;  3U7D A;  2ELA A;  4NY0 A;  2DN6 A;  5D27 A;  4PQ0 A;  3D8F A;  1ZVR A;  3WA0 A;  1TXD A;  1FGY A;  1BAK A;  3T06 A;  5C79 A;  3PP2 A;  1SGH A;  1DDV A;  4Z2N A;  5FI1 A;  5EFX A;  1E5W A;  2RNR B;  4HAV B;  3PG7 A;  1UEF A;  3HQC A;  2ROZ B;  3ODW A;  1X05 A;  2COD A;  4F7U P;  3DXC A;  2ELB A;  5JLJ B;  1M7R A;  2COA A;  1U27 A;  2CRF A;  4H8S A;  3TVV A;  2AL6 A;  1P3R A;  4BBK A;  1PFJ A;  2X18 A;  2YS1 A;  1W1D A;  1AQC A;  1MIZ B;  4A6K A;  1Y19 B;  2KCJ A;  4PNK A;  3MDB C;  3SYX A;  1EVH A;  2AEH A;  3MPX A;  2H7E A;  1NTY A;  1WG7 A;  3ODO A;  3AU4 A;  4A6F A;  3F0W A;  1X1G A;  1Y5O A;  2ADZ A;  1PMS A;  5DHA B;  4IFS A;  1WGQ A;  5J3Q A;  2LOX A;  1XKE A;  2YS3 A;  5DI9 B;  2K2J A;  2OQB A;  5KQ4 A;  3RCP A;  1H10 A;  3A8P A;  2L2I A;  2M38 A;  4HAT B;  2IFS A;  2K00 A;  2J0K A;  1OQN A;  1MPH A;  3IVF A;  1FOE A;  1X11 A;  4WVF B;  1KZG A;  1QC6 A;  1DYN A;  1X86 A;  3ULC A;  5HE3 A;  3KRW A;  4IAP A;  1KZ7 A;  2EMS A;  3TFM A;  3DXE A;  2L1C A;  1EAZ A;  2DYQ A;  3PVW A;  1TJ6 A;  2M14 A;  2H7D A;  2Y7B A;  2IYB A;  1K5G B;  1U2B A;  4KHO A;  1U29 A;  5HE1 A;  2DTC A;  4HB4 B;  3LJU X;  1V61 A;  1GG3 A;  4KHB B;  2KGX B;  3M1I B;  2RSG A;  2I1J A;  3VIA A;  5D3V A;  1U5E A;  2VSZ A;  4C0A A;  4ZRJ A;  4YON A;  2V76 A;  2PZ1 A;  2COF A;  1MK7 B;  5FI0 A;  3QIJ A;  3WYF B;  2D9Z A;  2GCJ A;  1NTV A;  4TYZ A;  2EJ8 A;  3D8E A;  3P6A A;  2J59 M;  5C16 A;  3HK0 A;  4DBB A;  2BCJ A;  1W1G A;  2NZ8 B;  2RGN B;  1NI2 A;  1U5G A;  3NSU A;  2DX5 A;  2W2W A;  4EJN A;  1WI1 A;  3P7Z A;  3OAN A;  1FHO A;  1SHC A;  1U5D A;  1UPR A;  5D3X A;  1DRO A;  1DDM A;  4GN1 A;  3PVL A;  1V5U A;  3CIK A;  3PEG A;  2Z0Q A;  3A98 B;  5CLQ B;  2EC1 A;  4WJ7 A;  2HTH B;  4HAU B;  2DX1 A;  2D9V A;  1U5F A;  1J19 A;  3N7C A;  1Z87 A;  3SV1 A;  2QKM A;  5C6R A;  3SO6 A;  2DLW A;  1FHW A;  5HE0 A;  2P0H A;  3G9W A;  4MY6 A;  4P7I A;  2YRY A;  4XWX A;  2OTX A;  5D3Y A;  4GXB A;  4Y94 A;  2CAY A;  2Q13 A;  5GOW B;  1XOD A;  5C5B B;  1BWN A;  2D9W A;  3FM8 C;  1RRP B;  1M7E A;  3O96 A;  2E2X A;  4WSF A;  5DHF B;  3UZT A;  4HB2 B;  4HAX B;  1GC6 A;  3BJI A;  4KAX B;  4DX8 A;  1ZSQ A;  1P6S A;  3FEH A;  1I7A A;  2I5F A;  2YSZ A;  3CXB B;  3AU5 A;  2W2X C;  3TO1 A;  5KCV A;  4GPT B;  2YVC A;  5LON B;  5J3Y A;  1J0W A;  3KY9 A;  1ISN A;  1N3H A;  3KRX A;  1V5P A;  1ZC3 B;  2I1K A;  2N23 A;  2EMT A;  2D9Y A;  2VKI A;  2RUK B;  1Q67 A;  3PZD A;  4F7G A;  2CY4 A;  2YF0 A;  1NU2 A;  4HDO A;  5HE2 A;  2KUP A;  1P5T A;  2RVB B;  2D4Q A;  2R09 A;  2MKR A;  5D3W A;  1UPQ A;  4HHV A;  2YS5 A;  1XCG A;  4EKU A;  2DHI A;  4NSW A;  1UNP A;  4A5K A;  1V88 A;  2I5C A;  1ZC4 B;  4HAW B;  3DXD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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