1BQTA

Three-dimensional structure of human insulin-like growth factor-i (igf-i) determined by 1h-nmr and distance geometry, 6 structures
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR-I
publication title Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
pubmed rcsb
source organism Homo sapiens
total genus 3
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1998-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1bqtA00
2KQPA 1H02B 1B9GA 1TGRA 5L3MA 3KR3D 3GF1A 2DSQC 2GF1A 1BQTA 1GZZB 1IMXA 5L3NA 1H59A 1PMXA 2DSPI 1WQJI 1SJUA 2JZQA 1ZEIA 5L3LA 2DSRI 1GZYB 6INSE 2L29B 2LWZA 4XSSB 1IGLA 2KJIA 3LRIA 1EFEA 1GZRB
chains in the Genus database with same CATH superfamily
2KQPA 1H02B 1B9GA 1TGRA 5L3MA 3KR3D 3GF1A 2DSQC 2GF1A 1BQTA 1GZZB 1IMXA 5L3NA 3F2BA 1H59A 1PMXA 2DSPI 1WQJI 1SJUA 2JZQA 1ZEIA 5L3LA 2L14B 2DSRI 1GZYB 6INSE 2L29B 2LWZA 4XSSB 1IGLA 2KJIA 3LRIA 3F2CA 3F2DA 1EFEA 1GZRB
chains in the Genus database with same CATH topology
2KQPA 1H02B 1B9GA 1TGRA 5L3MA 3KR3D 3GF1A 2DSQC 2GF1A 1BQTA 1GZZB 1IMXA 5L3NA 1H59A 1PMXA 2DSPI 1WQJI 1SJUA 2JZQA 1ZEIA 5L3LA 2DSRI 1GZYB 6INSE 2L29B 2LWZA 4XSSB 1IGLA 2KJIA 3LRIA 1EFEA 1GZRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KQP A;  1H02 B;  1B9G A;  1TGR A;  5L3M A;  3KR3 D;  3GF1 A;  2DSQ C;  2GF1 A;  1BQT A;  1GZZ B;  1IMX A;  5L3N A;  1H59 A;  1PMX A;  2DSP I;  1WQJ I;  1SJU A;  2JZQ A;  1ZEI A;  5L3L A;  2DSR I;  1GZY B;  6INS E;  2L29 B;  2LWZ A;  4XSS B;  1IGL A;  2KJI A;  3LRI A;  1EFE A;  1GZR B; 
#chains in the Genus database with same CATH topology
 2KQP A;  1H02 B;  1B9G A;  1TGR A;  5L3M A;  3KR3 D;  3GF1 A;  2DSQ C;  2GF1 A;  1BQT A;  1GZZ B;  1IMX A;  5L3N A;  3F2B A;  1H59 A;  1PMX A;  2DSP I;  1WQJ I;  1SJU A;  2JZQ A;  1ZEI A;  5L3L A;  2L14 B;  2DSR I;  1GZY B;  6INS E;  2L29 B;  2LWZ A;  4XSS B;  1IGL A;  2KJI A;  3LRI A;  3F2C A;  3F2D A;  1EFE A;  1GZR B; 
#chains in the Genus database with same CATH homology
 2KQP A;  1H02 B;  1B9G A;  1TGR A;  5L3M A;  3KR3 D;  3GF1 A;  2DSQ C;  2GF1 A;  1BQT A;  1GZZ B;  1IMX A;  5L3N A;  1H59 A;  1PMX A;  2DSP I;  1WQJ I;  1SJU A;  2JZQ A;  1ZEI A;  5L3L A;  2DSR I;  1GZY B;  6INS E;  2L29 B;  2LWZ A;  4XSS B;  1IGL A;  2KJI A;  3LRI A;  1EFE A;  1GZR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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