1DHJA

Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPASLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVSSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords DIHYDROFOLATE REDUCTASE
total genus 44
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1993-10-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1dhjA00
3ZPCA 3QLRA 1HFRA 1AOEA 4ELEA 3TQBA 3TQ8A 3UM6A 4FGGA 3F8ZA 3GHVA 1DR2A 1DAJA 2HM9A 2O7PA 1RD7A 4OR7A 5HSUA 3SRSX 3FY9X 3FYVX 3QLXA 3F0BX 3LG4A 3NZBX 4KJLA 4PSSA 3SRRX 1J3IA 1DRBA 1U71A 1DDRA 1RX3A 2BL9A 3SR5X 4DFRA 4PTJA 1RX4A 4M6LA 3L3RA 4H97A 4Q67A 1HFPA 4M2XA 4NX7A 3SA2A 1RX5A 2HXVA 3M08A 4KJKA 3DATA 1KMSA 4XT8A 2CIGA 3I8AX 2H2QA 4DPHA 3FRDX 2INQA 4Q0DA 4DDRA 1MVTA 1KMVA 7DFRA 1DYIA 3IX9A 3GI2A 3HJ3A 1DG5A 1S3VA 1RA1A 4FGHA 1RG7A 1DYJA 4KEBA 5HVBA 2FZJA 4P3QA 1IA2A 4XT5A 1VDRA 3OCHA 3FQZA 1RX7A 1U72A 3JW5A 4KYAA 2ANOA 3F0XX 4M6JA 8DFRA 3OAFA 4X5GA 4LEKX 4XT7A 4ELHA 1SEJA 5HPBA 2FZIA 2W3VA 3RO9A 4KAKA 3QG2A 3DL5A 3S9UA 1J3JA 3F0VX 3QGTA 1RB3A 4P66A 3D84X 4XT6A 5EAJA 4HOEA 5U26A 4Q6AA 3NXVA 3QLWA 4ELFA 3GHCA 4X5HA 2XW7A 1VJ3A 1DHFA 3EX8A 3JW3A 2OBCA 3FL8A 4M7VA 2L28A 3FQVA 3NZ9X 3JWCA 3TQ9A 2HQPA 4KL9A 3IROA 1DHIA 4X5IA 1HFQA 4EIGA 2FZHA 2BLAA 4EIZA 3NXOA 5DFRA 3I3RA 2QK8A 2W9TA 2ANQA 4ELBA 3F0SX 1DDSA 3GHWA 1DRAA 3K45A 3ROAA 1M78A 3JSUA 3F91A 1MVSA 1YHOA 4Q0EA 4QLGA 3NXXA 3DAUA 3QL3A 4KJJA 1LY3A 4G3MA 3SRQX 3K47A 6DFRA 4HA7A 4KM2A 4IXED 3NXYA 3EEKA 1OHKA 4P3RA 3FQ0A 1BOZA 3SGYA 2W9HA 2B3ZA 3NU0A 3D80A 4QJCA 1KLKA 2LF1A 1DF7A 3ZPGA 5HF0X 3FQCA 1DHJA 1CZ3A 1LY4A 3TQAA 5DXVA 1RA3A 4QLFA 3VCOA 3GYFA 2JYBA 3CD2A 4QJZD 5HUIA 5CC9A 4PSTA 1IA1A 3F0QX 1DYHA 4QLEA 3FRBX 5JA3A 1RX6A 5ECCA 3CLBA 5HI6A 1TDRA 3N0HA 3QLSA 5FDAA 2D0KA 3UM5A 4I1NA 4LAGX 4XE6X 4FHBA 5ECXA 2W3AA 1E26A 1S3YA 4ECKA 1DIUA 3UM8A 3KGYA 1DR6A 3EEJA 1RA2A 1DRHA 3NZCX 2C2TA 2KGKA 4GH8A 1DRFA 3EELA 3EIGA 4KD7A 3E0BA 5HF2X 4CD2A 1RA9A 1RE7A 2ITHA 4IXFX 4NX6A 3SH2A 1CD2A 2C2SA 4LAEX 4DPDA 5E8QA 1DISA 3QL0A 4PTHA 3M09A 4EILA 4KNEA 3SA1A 3NZAX 2AZNA 2W3MA 3RG9A 1M79A 1RB2A 4P68A 3S7AA 4HA9A 4IXGX 3K2HA 4M6KA 4KBNA 1IA3A 3FRFX 3JWKA 4ELGA 1DLSA 2DHFA 3JTWA 5JG0X 4G8ZX 3Q1HA 4X5FA 4X5JA 3FY8X 3JWFA 5HVEA 3NZ6X 5HQZA 1DREA 3NZDA 3S3VA 3NXTA 4QHVA 1RX1A 3FS6A 1RA8A 1RX2A 3F0UX 4G95A 1D1GA 1ZDRA 3QFXA 1J3KA 4KY4A 3NTZA 2BLBA 3FQFA 4M7UA 2G6VA 4DP3A 1OHJA 5HQYA 1JOLA 4KM0A 2BLCA 1QZFA 3FYWX 1DR5A 3QYOA 4EJ1A 4LAHX 4KY8A 1DR3A 3NXRA 2W3BA 3FQOA 3KFYA 3QLZA 5U27A 3EEMA 2W9SA 1AO8A 2W9GA 1U70A 3DG8A 3HBBA 3SRUX 5HSRA 4KFJA 3SQYX 4XRBA 1PD9A 1DYRA 4H95A 1RX9A 3IRNA 4HOFA 2ZZAA 3QLYA 1PD8A 1RC4A 2W3WA 3TD8A 4QI9A 2P4GA 3IRMA 2OIPA 3SAIA 4PSYA 1RH3A 1AI9A 3SRWX 3CSEA 2DRCA 4TU5X 3DL6A 3FREX 5HT4A 5CCCA 1IA4A 3FRAX 4H98A 4OSGA 2D5NA 3INVA 4KLXA 1PDBA 3FL9A 3NRRA 3F8YA 1DR7A 3IA4A 1S3UA 3DFRA 1BZFA 3QYLA 1M7AA 5HT5A 3DRCA 3IA5A 3KY8A 4XT4A 4H96A 1DLRA 4XECX 4PDJA 1DR4A 2CD2A 3JWMA 3R33A 1LUDA 3K74A 1DG8A 3DGAA 1DR1A 1JUVA 3JVXA 2GD9A 1S3WA 1RX8A 1JOMA 3KJSA 4HOGA 4RGCA 4I13A 3KJRA 3CL9A 1DG7A 1RF7A
chains in the Genus database with same CATH superfamily
3ZPCA 3QLRA 1HFRA 1AOEA 4ELEA 3TQBA 3TQ8A 3UM6A 4FGGA 3F8ZA 3GHVA 1DR2A 1DAJA 2HM9A 2O7PA 1RD7A 4OR7A 5HSUA 3SRSX 3FY9X 3FYVX 3QLXA 3F0BX 3LG4A 3NZBX 4KJLA 4PSSA 3SRRX 1J3IA 1DRBA 1U71A 1DDRA 1RX3A 2BL9A 3SR5X 4DFRA 4PTJA 1RX4A 4M6LA 3L3RA 4H97A 4Q67A 1HFPA 4M2XA 4NX7A 3SA2A 1RX5A 2HXVA 3M08A 4KJKA 3DATA 1KMSA 4XT8A 2CIGA 3I8AX 2H2QA 4DPHA 3FRDX 2INQA 4Q0DA 4DDRA 1MVTA 1KMVA 7DFRA 1DYIA 3IX9A 3GI2A 3HJ3A 1DG5A 1S3VA 1RA1A 4FGHA 1RG7A 1DYJA 4KEBA 5HVBA 2FZJA 4P3QA 1IA2A 4XT5A 1VDRA 3OCHA 3FQZA 1RX7A 1U72A 3JW5A 4KYAA 2ANOA 3F0XX 4M6JA 8DFRA 3OAFA 4X5GA 4LEKX 4XT7A 4ELHA 1SEJA 5HPBA 2FZIA 2W3VA 3RO9A 4KAKA 3QG2A 3DL5A 3S9UA 1J3JA 3F0VX 3QGTA 1RB3A 4P66A 3D84X 4XT6A 5EAJA 4HOEA 5U26A 4Q6AA 3NXVA 3QLWA 4ELFA 3GHCA 4X5HA 2XW7A 1VJ3A 1DHFA 3EX8A 3JW3A 2OBCA 3FL8A 4M7VA 2L28A 3FQVA 3NZ9X 3JWCA 3TQ9A 2HQPA 4KL9A 3IROA 1DHIA 4X5IA 1HFQA 4EIGA 2FZHA 2BLAA 4EIZA 3NXOA 5DFRA 3I3RA 2QK8A 2W9TA 2ANQA 4ELBA 3F0SX 1DDSA 3GHWA 1DRAA 3K45A 3ROAA 1M78A 3JSUA 3F91A 1MVSA 1YHOA 4Q0EA 4QLGA 3NXXA 3DAUA 3QL3A 4KJJA 1LY3A 4G3MA 3SRQX 3K47A 6DFRA 4HA7A 4KM2A 4IXED 3NXYA 3EEKA 1OHKA 4P3RA 3FQ0A 1BOZA 3SGYA 2W9HA 2B3ZA 3NU0A 3D80A 4QJCA 1KLKA 2LF1A 1DF7A 3ZPGA 5HF0X 3FQCA 1DHJA 1CZ3A 1LY4A 3TQAA 5DXVA 1RA3A 4QLFA 3VCOA 3GYFA 2JYBA 3CD2A 4QJZD 5HUIA 5CC9A 4PSTA 1IA1A 3F0QX 1DYHA 4QLEA 3FRBX 5JA3A 1RX6A 5ECCA 3CLBA 5HI6A 1TDRA 3N0HA 3QLSA 5FDAA 2D0KA 3UM5A 4I1NA 4LAGX 4XE6X 4FHBA 5ECXA 2W3AA 1E26A 1S3YA 4ECKA 1DIUA 3UM8A 3KGYA 1DR6A 3EEJA 1RA2A 1DRHA 3NZCX 2C2TA 2KGKA 4GH8A 1DRFA 3EELA 3EIGA 4KD7A 3E0BA 5HF2X 4CD2A 1RA9A 1RE7A 2ITHA 4IXFX 4NX6A 3SH2A 1CD2A 2C2SA 4LAEX 4DPDA 5E8QA 1DISA 3QL0A 4PTHA 3M09A 4EILA 4KNEA 3SA1A 3NZAX 2AZNA 2W3MA 3RG9A 1M79A 1RB2A 4P68A 3S7AA 4HA9A 4IXGX 3K2HA 4M6KA 4KBNA 1IA3A 3FRFX 3JWKA 4ELGA 1DLSA 2DHFA 3JTWA 5JG0X 4G8ZX 3Q1HA 4X5FA 4X5JA 3FY8X 3JWFA 5HVEA 3NZ6X 5HQZA 1DREA 3NZDA 3S3VA 3NXTA 4QHVA 1RX1A 3FS6A 1RA8A 1RX2A 3F0UX 4G95A 1D1GA 1ZDRA 3QFXA 1J3KA 4KY4A 3NTZA 2BLBA 3FQFA 4M7UA 2G6VA 4DP3A 1OHJA 5HQYA 1JOLA 4KM0A 2BLCA 1QZFA 3FYWX 1DR5A 3QYOA 4EJ1A 4LAHX 4KY8A 1DR3A 3NXRA 2W3BA 3FQOA 3KFYA 3QLZA 5U27A 3EEMA 2W9SA 1AO8A 2W9GA 1U70A 3DG8A 3HBBA 3SRUX 5HSRA 4KFJA 3SQYX 4XRBA 1PD9A 1DYRA 4H95A 1RX9A 3IRNA 4HOFA 2ZZAA 3QLYA 1PD8A 1RC4A 2W3WA 3TD8A 4QI9A 2P4GA 3IRMA 2OIPA 3SAIA 4PSYA 1RH3A 1AI9A 3SRWX 3CSEA 2DRCA 4TU5X 3DL6A 3FREX 5HT4A 5CCCA 1IA4A 3FRAX 4H98A 4OSGA 2D5NA 3INVA 4KLXA 1PDBA 3FL9A 3NRRA 3F8YA 1DR7A 3IA4A 1S3UA 3DFRA 1BZFA 3QYLA 1M7AA 5HT5A 3DRCA 3IA5A 3KY8A 4XT4A 4H96A 1DLRA 4XECX 4PDJA 1DR4A 2CD2A 3JWMA 3R33A 1LUDA 3K74A 1DG8A 3DGAA 1DR1A 1JUVA 3JVXA 2GD9A 1S3WA 1RX8A 1JOMA 3KJSA 4HOGA 4RGCA 4I13A 3KJRA 3CL9A 1DG7A 1RF7A
chains in the Genus database with same CATH topology
3ZPCA 3QLRA 1HFRA 1AOEA 4ELEA 3TQBA 3TQ8A 3UM6A 4FGGA 3F8ZA 3GHVA 1DR2A 1DAJA 2HM9A 2O7PA 1RD7A 4OR7A 5HSUA 3SRSX 3FY9X 3FYVX 3QLXA 3F0BX 3LG4A 3NZBX 4KJLA 4PSSA 3SRRX 1J3IA 1DRBA 1U71A 1DDRA 1RX3A 2BL9A 3SR5X 4DFRA 4PTJA 1RX4A 4M6LA 3L3RA 4H97A 4Q67A 1HFPA 4M2XA 4NX7A 3SA2A 1RX5A 2HXVA 3M08A 4KJKA 3DATA 1KMSA 4XT8A 2CIGA 3I8AX 2H2QA 4DPHA 3FRDX 2INQA 4Q0DA 4DDRA 1MVTA 1KMVA 7DFRA 1DYIA 3IX9A 3GI2A 3HJ3A 1DG5A 1S3VA 1RA1A 4FGHA 1RG7A 1DYJA 4KEBA 5HVBA 2FZJA 4P3QA 1IA2A 4XT5A 1VDRA 3OCHA 3FQZA 1RX7A 1U72A 3JW5A 4KYAA 2ANOA 3F0XX 4M6JA 8DFRA 3OAFA 4X5GA 4LEKX 4XT7A 4ELHA 1SEJA 5HPBA 2FZIA 2W3VA 3RO9A 4KAKA 3QG2A 3DL5A 3S9UA 1J3JA 3F0VX 3QGTA 1RB3A 4P66A 3D84X 4XT6A 5EAJA 4HOEA 5U26A 4Q6AA 3NXVA 3QLWA 4ELFA 3GHCA 4X5HA 2XW7A 1VJ3A 1DHFA 3EX8A 3JW3A 2OBCA 3FL8A 4M7VA 2L28A 3FQVA 3NZ9X 3JWCA 3TQ9A 2HQPA 4KL9A 3IROA 1DHIA 4X5IA 1HFQA 4EIGA 2FZHA 2BLAA 4EIZA 3NXOA 5DFRA 3I3RA 2QK8A 2W9TA 2ANQA 4ELBA 3F0SX 1DDSA 3GHWA 1DRAA 3K45A 3ROAA 1M78A 3JSUA 3F91A 1MVSA 1YHOA 4Q0EA 4QLGA 3NXXA 3DAUA 3QL3A 4KJJA 1LY3A 4G3MA 3SRQX 3K47A 6DFRA 4HA7A 4KM2A 4IXED 3NXYA 3EEKA 1OHKA 4P3RA 3FQ0A 1BOZA 3SGYA 2W9HA 2B3ZA 3NU0A 3D80A 4QJCA 1KLKA 2LF1A 1DF7A 3ZPGA 5HF0X 3FQCA 1DHJA 1CZ3A 1LY4A 3TQAA 5DXVA 1RA3A 4QLFA 3VCOA 3GYFA 2JYBA 3CD2A 4QJZD 5HUIA 5CC9A 4PSTA 1IA1A 3F0QX 1DYHA 4QLEA 3FRBX 5JA3A 1RX6A 5ECCA 3CLBA 5HI6A 1TDRA 3N0HA 3QLSA 5FDAA 2D0KA 3UM5A 4I1NA 4LAGX 4XE6X 4FHBA 5ECXA 2W3AA 1E26A 1S3YA 4ECKA 1DIUA 3UM8A 3KGYA 1DR6A 3EEJA 1RA2A 1DRHA 3NZCX 2C2TA 2KGKA 4GH8A 1DRFA 3EELA 3EIGA 4KD7A 3E0BA 5HF2X 4CD2A 1RA9A 1RE7A 2ITHA 4IXFX 4NX6A 3SH2A 1CD2A 2C2SA 4LAEX 4DPDA 5E8QA 1DISA 3QL0A 4PTHA 3M09A 4EILA 4KNEA 3SA1A 3NZAX 2AZNA 2W3MA 3RG9A 1M79A 1RB2A 4P68A 3S7AA 4HA9A 4IXGX 3K2HA 4M6KA 4KBNA 1IA3A 3FRFX 3JWKA 4ELGA 1DLSA 2DHFA 3JTWA 5JG0X 4G8ZX 3Q1HA 4X5FA 4X5JA 3FY8X 3JWFA 5HVEA 3NZ6X 5HQZA 1DREA 3NZDA 3S3VA 3NXTA 4QHVA 1RX1A 3FS6A 1RA8A 1RX2A 3F0UX 4G95A 1D1GA 1ZDRA 3QFXA 1J3KA 4KY4A 3NTZA 2BLBA 3FQFA 4M7UA 2G6VA 4DP3A 1OHJA 5HQYA 1JOLA 4KM0A 2BLCA 1QZFA 3FYWX 1DR5A 3QYOA 4EJ1A 4LAHX 4KY8A 1DR3A 3NXRA 2W3BA 3FQOA 3KFYA 3QLZA 5U27A 3EEMA 2W9SA 1AO8A 2W9GA 1U70A 3DG8A 3HBBA 3SRUX 5HSRA 4KFJA 3SQYX 4XRBA 1PD9A 1DYRA 4H95A 1RX9A 3IRNA 4HOFA 2ZZAA 3QLYA 1PD8A 1RC4A 2W3WA 3TD8A 4QI9A 2P4GA 3IRMA 2OIPA 3SAIA 4PSYA 1RH3A 1AI9A 3SRWX 3CSEA 2DRCA 4TU5X 3DL6A 3FREX 5HT4A 5CCCA 1IA4A 3FRAX 4H98A 4OSGA 2D5NA 3INVA 4KLXA 1PDBA 3FL9A 3NRRA 3F8YA 1DR7A 3IA4A 1S3UA 3DFRA 1BZFA 3QYLA 1M7AA 5HT5A 3DRCA 3IA5A 3KY8A 4XT4A 4H96A 1DLRA 4XECX 4PDJA 1DR4A 2CD2A 3JWMA 3R33A 1LUDA 3K74A 1DG8A 3DGAA 1DR1A 1JUVA 3JVXA 2GD9A 1S3WA 1RX8A 1JOMA 3KJSA 4HOGA 4RGCA 4I13A 3KJRA 3CL9A 1DG7A 1RF7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZPC A;  3QLR A;  1HFR A;  1AOE A;  4ELE A;  3TQB A;  3TQ8 A;  3UM6 A;  4FGG A;  3F8Z A;  3GHV A;  1DR2 A;  1DAJ A;  2HM9 A;  2O7P A;  1RD7 A;  4OR7 A;  5HSU A;  3SRS X;  3FY9 X;  3FYV X;  3QLX A;  3F0B X;  3LG4 A;  3NZB X;  4KJL A;  4PSS A;  3SRR X;  1J3I A;  1DRB A;  1U71 A;  1DDR A;  1RX3 A;  2BL9 A;  3SR5 X;  4DFR A;  4PTJ A;  1RX4 A;  4M6L A;  3L3R A;  4H97 A;  4Q67 A;  1HFP A;  4M2X A;  4NX7 A;  3SA2 A;  1RX5 A;  2HXV A;  3M08 A;  4KJK A;  3DAT A;  1KMS A;  4XT8 A;  2CIG A;  3I8A X;  2H2Q A;  4DPH A;  3FRD X;  2INQ A;  4Q0D A;  4DDR A;  1MVT A;  1KMV A;  7DFR A;  1DYI A;  3IX9 A;  3GI2 A;  3HJ3 A;  1DG5 A;  1S3V A;  1RA1 A;  4FGH A;  1RG7 A;  1DYJ A;  4KEB A;  5HVB A;  2FZJ A;  4P3Q A;  1IA2 A;  4XT5 A;  1VDR A;  3OCH A;  3FQZ A;  1RX7 A;  1U72 A;  3JW5 A;  4KYA A;  2ANO A;  3F0X X;  4M6J A;  8DFR A;  3OAF A;  4X5G A;  4LEK X;  4XT7 A;  4ELH A;  1SEJ A;  5HPB A;  2FZI A;  2W3V A;  3RO9 A;  4KAK A;  3QG2 A;  3DL5 A;  3S9U A;  1J3J A;  3F0V X;  3QGT A;  1RB3 A;  4P66 A;  3D84 X;  4XT6 A;  5EAJ A;  4HOE A;  5U26 A;  4Q6A A;  3NXV A;  3QLW A;  4ELF A;  3GHC A;  4X5H A;  2XW7 A;  1VJ3 A;  1DHF A;  3EX8 A;  3JW3 A;  2OBC A;  3FL8 A;  4M7V A;  2L28 A;  3FQV A;  3NZ9 X;  3JWC A;  3TQ9 A;  2HQP A;  4KL9 A;  3IRO A;  1DHI A;  4X5I A;  1HFQ A;  4EIG A;  2FZH A;  2BLA A;  4EIZ A;  3NXO A;  5DFR A;  3I3R A;  2QK8 A;  2W9T A;  2ANQ A;  4ELB A;  3F0S X;  1DDS A;  3GHW A;  1DRA A;  3K45 A;  3ROA A;  1M78 A;  3JSU A;  3F91 A;  1MVS A;  1YHO A;  4Q0E A;  4QLG A;  3NXX A;  3DAU A;  3QL3 A;  4KJJ A;  1LY3 A;  4G3M A;  3SRQ X;  3K47 A;  6DFR A;  4HA7 A;  4KM2 A;  4IXE D;  3NXY A;  3EEK A;  1OHK A;  4P3R A;  3FQ0 A;  1BOZ A;  3SGY A;  2W9H A;  2B3Z A;  3NU0 A;  3D80 A;  4QJC A;  1KLK A;  2LF1 A;  1DF7 A;  3ZPG A;  5HF0 X;  3FQC A;  1DHJ A;  1CZ3 A;  1LY4 A;  3TQA A;  5DXV A;  1RA3 A;  4QLF A;  3VCO A;  3GYF A;  2JYB A;  3CD2 A;  4QJZ D;  5HUI A;  5CC9 A;  4PST A;  1IA1 A;  3F0Q X;  1DYH A;  4QLE A;  3FRB X;  5JA3 A;  1RX6 A;  5ECC A;  3CLB A;  5HI6 A;  1TDR A;  3N0H A;  3QLS A;  5FDA A;  2D0K A;  3UM5 A;  4I1N A;  4LAG X;  4XE6 X;  4FHB A;  5ECX A;  2W3A A;  1E26 A;  1S3Y A;  4ECK A;  1DIU A;  3UM8 A;  3KGY A;  1DR6 A;  3EEJ A;  1RA2 A;  1DRH A;  3NZC X;  2C2T A;  2KGK A;  4GH8 A;  1DRF A;  3EEL A;  3EIG A;  4KD7 A;  3E0B A;  5HF2 X;  4CD2 A;  1RA9 A;  1RE7 A;  2ITH A;  4IXF X;  4NX6 A;  3SH2 A;  1CD2 A;  2C2S A;  4LAE X;  4DPD A;  5E8Q A;  1DIS A;  3QL0 A;  4PTH A;  3M09 A;  4EIL A;  4KNE A;  3SA1 A;  3NZA X;  2AZN A;  2W3M A;  3RG9 A;  1M79 A;  1RB2 A;  4P68 A;  3S7A A;  4HA9 A;  4IXG X;  3K2H A;  4M6K A;  4KBN A;  1IA3 A;  3FRF X;  3JWK A;  4ELG A;  1DLS A;  2DHF A;  3JTW A;  5JG0 X;  4G8Z X;  3Q1H A;  4X5F A;  4X5J A;  3FY8 X;  3JWF A;  5HVE A;  3NZ6 X;  5HQZ A;  1DRE A;  3NZD A;  3S3V A;  3NXT A;  4QHV A;  1RX1 A;  3FS6 A;  1RA8 A;  1RX2 A;  3F0U X;  4G95 A;  1D1G A;  1ZDR A;  3QFX A;  1J3K A;  4KY4 A;  3NTZ A;  2BLB A;  3FQF A;  4M7U A;  2G6V A;  4DP3 A;  1OHJ A;  5HQY A;  1JOL A;  4KM0 A;  2BLC A;  1QZF A;  3FYW X;  1DR5 A;  3QYO A;  4EJ1 A;  4LAH X;  4KY8 A;  1DR3 A;  3NXR A;  2W3B A;  3FQO A;  3KFY A;  3QLZ A;  5U27 A;  3EEM A;  2W9S A;  1AO8 A;  2W9G A;  1U70 A;  3DG8 A;  3HBB A;  3SRU X;  5HSR A;  4KFJ A;  3SQY X;  4XRB A;  1PD9 A;  1DYR A;  4H95 A;  1RX9 A;  3IRN A;  4HOF A;  2ZZA A;  3QLY A;  1PD8 A;  1RC4 A;  2W3W A;  3TD8 A;  4QI9 A;  2P4G A;  3IRM A;  2OIP A;  3SAI A;  4PSY A;  1RH3 A;  1AI9 A;  3SRW X;  3CSE A;  2DRC A;  4TU5 X;  3DL6 A;  3FRE X;  5HT4 A;  5CCC A;  1IA4 A;  3FRA X;  4H98 A;  4OSG A;  2D5N A;  3INV A;  4KLX A;  1PDB A;  3FL9 A;  3NRR A;  3F8Y A;  1DR7 A;  3IA4 A;  1S3U A;  3DFR A;  1BZF A;  3QYL A;  1M7A A;  5HT5 A;  3DRC A;  3IA5 A;  3KY8 A;  4XT4 A;  4H96 A;  1DLR A;  4XEC X;  4PDJ A;  1DR4 A;  2CD2 A;  3JWM A;  3R33 A;  1LUD A;  3K74 A;  1DG8 A;  3DGA A;  1DR1 A;  1JUV A;  3JVX A;  2GD9 A;  1S3W A;  1RX8 A;  1JOM A;  3KJS A;  4HOG A;  4RGC A;  4I13 A;  3KJR A;  3CL9 A;  1DG7 A;  1RF7 A; 
#chains in the Genus database with same CATH topology
 3ZPC A;  3QLR A;  1HFR A;  1AOE A;  4ELE A;  3TQB A;  3TQ8 A;  3UM6 A;  4FGG A;  3F8Z A;  3GHV A;  1DR2 A;  1DAJ A;  2HM9 A;  2O7P A;  1RD7 A;  4OR7 A;  5HSU A;  3SRS X;  3FY9 X;  3FYV X;  3QLX A;  3F0B X;  3LG4 A;  3NZB X;  4KJL A;  4PSS A;  3SRR X;  1J3I A;  1DRB A;  1U71 A;  1DDR A;  1RX3 A;  2BL9 A;  3SR5 X;  4DFR A;  4PTJ A;  1RX4 A;  4M6L A;  3L3R A;  4H97 A;  4Q67 A;  1HFP A;  4M2X A;  4NX7 A;  3SA2 A;  1RX5 A;  2HXV A;  3M08 A;  4KJK A;  3DAT A;  1KMS A;  4XT8 A;  2CIG A;  3I8A X;  2H2Q A;  4DPH A;  3FRD X;  2INQ A;  4Q0D A;  4DDR A;  1MVT A;  1KMV A;  7DFR A;  1DYI A;  3IX9 A;  3GI2 A;  3HJ3 A;  1DG5 A;  1S3V A;  1RA1 A;  4FGH A;  1RG7 A;  1DYJ A;  4KEB A;  5HVB A;  2FZJ A;  4P3Q A;  1IA2 A;  4XT5 A;  1VDR A;  3OCH A;  3FQZ A;  1RX7 A;  1U72 A;  3JW5 A;  4KYA A;  2ANO A;  3F0X X;  4M6J A;  8DFR A;  3OAF A;  4X5G A;  4LEK X;  4XT7 A;  4ELH A;  1SEJ A;  5HPB A;  2FZI A;  2W3V A;  3RO9 A;  4KAK A;  3QG2 A;  3DL5 A;  3S9U A;  1J3J A;  3F0V X;  3QGT A;  1RB3 A;  4P66 A;  3D84 X;  4XT6 A;  5EAJ A;  4HOE A;  5U26 A;  4Q6A A;  3NXV A;  3QLW A;  4ELF A;  3GHC A;  4X5H A;  2XW7 A;  1VJ3 A;  1DHF A;  3EX8 A;  3JW3 A;  2OBC A;  3FL8 A;  4M7V A;  2L28 A;  3FQV A;  3NZ9 X;  3JWC A;  3TQ9 A;  2HQP A;  4KL9 A;  3IRO A;  1DHI A;  4X5I A;  1HFQ A;  4EIG A;  2FZH A;  2BLA A;  4EIZ A;  3NXO A;  5DFR A;  3I3R A;  2QK8 A;  2W9T A;  2ANQ A;  4ELB A;  3F0S X;  1DDS A;  3GHW A;  1DRA A;  3K45 A;  3ROA A;  1M78 A;  3JSU A;  3F91 A;  1MVS A;  1YHO A;  4Q0E A;  4QLG A;  3NXX A;  3DAU A;  3QL3 A;  4KJJ A;  1LY3 A;  4G3M A;  3SRQ X;  3K47 A;  6DFR A;  4HA7 A;  4KM2 A;  4IXE D;  3NXY A;  3EEK A;  1OHK A;  4P3R A;  3FQ0 A;  1BOZ A;  3SGY A;  2W9H A;  2B3Z A;  3NU0 A;  3D80 A;  4QJC A;  1KLK A;  2LF1 A;  1DF7 A;  3ZPG A;  5HF0 X;  3FQC A;  1DHJ A;  1CZ3 A;  1LY4 A;  3TQA A;  5DXV A;  1RA3 A;  4QLF A;  3VCO A;  3GYF A;  2JYB A;  3CD2 A;  4QJZ D;  5HUI A;  5CC9 A;  4PST A;  1IA1 A;  3F0Q X;  1DYH A;  4QLE A;  3FRB X;  5JA3 A;  1RX6 A;  5ECC A;  3CLB A;  5HI6 A;  1TDR A;  3N0H A;  3QLS A;  5FDA A;  2D0K A;  3UM5 A;  4I1N A;  4LAG X;  4XE6 X;  4FHB A;  5ECX A;  2W3A A;  1E26 A;  1S3Y A;  4ECK A;  1DIU A;  3UM8 A;  3KGY A;  1DR6 A;  3EEJ A;  1RA2 A;  1DRH A;  3NZC X;  2C2T A;  2KGK A;  4GH8 A;  1DRF A;  3EEL A;  3EIG A;  4KD7 A;  3E0B A;  5HF2 X;  4CD2 A;  1RA9 A;  1RE7 A;  2ITH A;  4IXF X;  4NX6 A;  3SH2 A;  1CD2 A;  2C2S A;  4LAE X;  4DPD A;  5E8Q A;  1DIS A;  3QL0 A;  4PTH A;  3M09 A;  4EIL A;  4KNE A;  3SA1 A;  3NZA X;  2AZN A;  2W3M A;  3RG9 A;  1M79 A;  1RB2 A;  4P68 A;  3S7A A;  4HA9 A;  4IXG X;  3K2H A;  4M6K A;  4KBN A;  1IA3 A;  3FRF X;  3JWK A;  4ELG A;  1DLS A;  2DHF A;  3JTW A;  5JG0 X;  4G8Z X;  3Q1H A;  4X5F A;  4X5J A;  3FY8 X;  3JWF A;  5HVE A;  3NZ6 X;  5HQZ A;  1DRE A;  3NZD A;  3S3V A;  3NXT A;  4QHV A;  1RX1 A;  3FS6 A;  1RA8 A;  1RX2 A;  3F0U X;  4G95 A;  1D1G A;  1ZDR A;  3QFX A;  1J3K A;  4KY4 A;  3NTZ A;  2BLB A;  3FQF A;  4M7U A;  2G6V A;  4DP3 A;  1OHJ A;  5HQY A;  1JOL A;  4KM0 A;  2BLC A;  1QZF A;  3FYW X;  1DR5 A;  3QYO A;  4EJ1 A;  4LAH X;  4KY8 A;  1DR3 A;  3NXR A;  2W3B A;  3FQO A;  3KFY A;  3QLZ A;  5U27 A;  3EEM A;  2W9S A;  1AO8 A;  2W9G A;  1U70 A;  3DG8 A;  3HBB A;  3SRU X;  5HSR A;  4KFJ A;  3SQY X;  4XRB A;  1PD9 A;  1DYR A;  4H95 A;  1RX9 A;  3IRN A;  4HOF A;  2ZZA A;  3QLY A;  1PD8 A;  1RC4 A;  2W3W A;  3TD8 A;  4QI9 A;  2P4G A;  3IRM A;  2OIP A;  3SAI A;  4PSY A;  1RH3 A;  1AI9 A;  3SRW X;  3CSE A;  2DRC A;  4TU5 X;  3DL6 A;  3FRE X;  5HT4 A;  5CCC A;  1IA4 A;  3FRA X;  4H98 A;  4OSG A;  2D5N A;  3INV A;  4KLX A;  1PDB A;  3FL9 A;  3NRR A;  3F8Y A;  1DR7 A;  3IA4 A;  1S3U A;  3DFR A;  1BZF A;  3QYL A;  1M7A A;  5HT5 A;  3DRC A;  3IA5 A;  3KY8 A;  4XT4 A;  4H96 A;  1DLR A;  4XEC X;  4PDJ A;  1DR4 A;  2CD2 A;  3JWM A;  3R33 A;  1LUD A;  3K74 A;  1DG8 A;  3DGA A;  1DR1 A;  1JUV A;  3JVX A;  2GD9 A;  1S3W A;  1RX8 A;  1JOM A;  3KJS A;  4HOG A;  4RGC A;  4I13 A;  3KJR A;  3CL9 A;  1DG7 A;  1RF7 A; 
#chains in the Genus database with same CATH homology
 3ZPC A;  3QLR A;  1HFR A;  1AOE A;  4ELE A;  3TQB A;  3TQ8 A;  3UM6 A;  4FGG A;  3F8Z A;  3GHV A;  1DR2 A;  1DAJ A;  2HM9 A;  2O7P A;  1RD7 A;  4OR7 A;  5HSU A;  3SRS X;  3FY9 X;  3FYV X;  3QLX A;  3F0B X;  3LG4 A;  3NZB X;  4KJL A;  4PSS A;  3SRR X;  1J3I A;  1DRB A;  1U71 A;  1DDR A;  1RX3 A;  2BL9 A;  3SR5 X;  4DFR A;  4PTJ A;  1RX4 A;  4M6L A;  3L3R A;  4H97 A;  4Q67 A;  1HFP A;  4M2X A;  4NX7 A;  3SA2 A;  1RX5 A;  2HXV A;  3M08 A;  4KJK A;  3DAT A;  1KMS A;  4XT8 A;  2CIG A;  3I8A X;  2H2Q A;  4DPH A;  3FRD X;  2INQ A;  4Q0D A;  4DDR A;  1MVT A;  1KMV A;  7DFR A;  1DYI A;  3IX9 A;  3GI2 A;  3HJ3 A;  1DG5 A;  1S3V A;  1RA1 A;  4FGH A;  1RG7 A;  1DYJ A;  4KEB A;  5HVB A;  2FZJ A;  4P3Q A;  1IA2 A;  4XT5 A;  1VDR A;  3OCH A;  3FQZ A;  1RX7 A;  1U72 A;  3JW5 A;  4KYA A;  2ANO A;  3F0X X;  4M6J A;  8DFR A;  3OAF A;  4X5G A;  4LEK X;  4XT7 A;  4ELH A;  1SEJ A;  5HPB A;  2FZI A;  2W3V A;  3RO9 A;  4KAK A;  3QG2 A;  3DL5 A;  3S9U A;  1J3J A;  3F0V X;  3QGT A;  1RB3 A;  4P66 A;  3D84 X;  4XT6 A;  5EAJ A;  4HOE A;  5U26 A;  4Q6A A;  3NXV A;  3QLW A;  4ELF A;  3GHC A;  4X5H A;  2XW7 A;  1VJ3 A;  1DHF A;  3EX8 A;  3JW3 A;  2OBC A;  3FL8 A;  4M7V A;  2L28 A;  3FQV A;  3NZ9 X;  3JWC A;  3TQ9 A;  2HQP A;  4KL9 A;  3IRO A;  1DHI A;  4X5I A;  1HFQ A;  4EIG A;  2FZH A;  2BLA A;  4EIZ A;  3NXO A;  5DFR A;  3I3R A;  2QK8 A;  2W9T A;  2ANQ A;  4ELB A;  3F0S X;  1DDS A;  3GHW A;  1DRA A;  3K45 A;  3ROA A;  1M78 A;  3JSU A;  3F91 A;  1MVS A;  1YHO A;  4Q0E A;  4QLG A;  3NXX A;  3DAU A;  3QL3 A;  4KJJ A;  1LY3 A;  4G3M A;  3SRQ X;  3K47 A;  6DFR A;  4HA7 A;  4KM2 A;  4IXE D;  3NXY A;  3EEK A;  1OHK A;  4P3R A;  3FQ0 A;  1BOZ A;  3SGY A;  2W9H A;  2B3Z A;  3NU0 A;  3D80 A;  4QJC A;  1KLK A;  2LF1 A;  1DF7 A;  3ZPG A;  5HF0 X;  3FQC A;  1DHJ A;  1CZ3 A;  1LY4 A;  3TQA A;  5DXV A;  1RA3 A;  4QLF A;  3VCO A;  3GYF A;  2JYB A;  3CD2 A;  4QJZ D;  5HUI A;  5CC9 A;  4PST A;  1IA1 A;  3F0Q X;  1DYH A;  4QLE A;  3FRB X;  5JA3 A;  1RX6 A;  5ECC A;  3CLB A;  5HI6 A;  1TDR A;  3N0H A;  3QLS A;  5FDA A;  2D0K A;  3UM5 A;  4I1N A;  4LAG X;  4XE6 X;  4FHB A;  5ECX A;  2W3A A;  1E26 A;  1S3Y A;  4ECK A;  1DIU A;  3UM8 A;  3KGY A;  1DR6 A;  3EEJ A;  1RA2 A;  1DRH A;  3NZC X;  2C2T A;  2KGK A;  4GH8 A;  1DRF A;  3EEL A;  3EIG A;  4KD7 A;  3E0B A;  5HF2 X;  4CD2 A;  1RA9 A;  1RE7 A;  2ITH A;  4IXF X;  4NX6 A;  3SH2 A;  1CD2 A;  2C2S A;  4LAE X;  4DPD A;  5E8Q A;  1DIS A;  3QL0 A;  4PTH A;  3M09 A;  4EIL A;  4KNE A;  3SA1 A;  3NZA X;  2AZN A;  2W3M A;  3RG9 A;  1M79 A;  1RB2 A;  4P68 A;  3S7A A;  4HA9 A;  4IXG X;  3K2H A;  4M6K A;  4KBN A;  1IA3 A;  3FRF X;  3JWK A;  4ELG A;  1DLS A;  2DHF A;  3JTW A;  5JG0 X;  4G8Z X;  3Q1H A;  4X5F A;  4X5J A;  3FY8 X;  3JWF A;  5HVE A;  3NZ6 X;  5HQZ A;  1DRE A;  3NZD A;  3S3V A;  3NXT A;  4QHV A;  1RX1 A;  3FS6 A;  1RA8 A;  1RX2 A;  3F0U X;  4G95 A;  1D1G A;  1ZDR A;  3QFX A;  1J3K A;  4KY4 A;  3NTZ A;  2BLB A;  3FQF A;  4M7U A;  2G6V A;  4DP3 A;  1OHJ A;  5HQY A;  1JOL A;  4KM0 A;  2BLC A;  1QZF A;  3FYW X;  1DR5 A;  3QYO A;  4EJ1 A;  4LAH X;  4KY8 A;  1DR3 A;  3NXR A;  2W3B A;  3FQO A;  3KFY A;  3QLZ A;  5U27 A;  3EEM A;  2W9S A;  1AO8 A;  2W9G A;  1U70 A;  3DG8 A;  3HBB A;  3SRU X;  5HSR A;  4KFJ A;  3SQY X;  4XRB A;  1PD9 A;  1DYR A;  4H95 A;  1RX9 A;  3IRN A;  4HOF A;  2ZZA A;  3QLY A;  1PD8 A;  1RC4 A;  2W3W A;  3TD8 A;  4QI9 A;  2P4G A;  3IRM A;  2OIP A;  3SAI A;  4PSY A;  1RH3 A;  1AI9 A;  3SRW X;  3CSE A;  2DRC A;  4TU5 X;  3DL6 A;  3FRE X;  5HT4 A;  5CCC A;  1IA4 A;  3FRA X;  4H98 A;  4OSG A;  2D5N A;  3INV A;  4KLX A;  1PDB A;  3FL9 A;  3NRR A;  3F8Y A;  1DR7 A;  3IA4 A;  1S3U A;  3DFR A;  1BZF A;  3QYL A;  1M7A A;  5HT5 A;  3DRC A;  3IA5 A;  3KY8 A;  4XT4 A;  4H96 A;  1DLR A;  4XEC X;  4PDJ A;  1DR4 A;  2CD2 A;  3JWM A;  3R33 A;  1LUD A;  3K74 A;  1DG8 A;  3DGA A;  1DR1 A;  1JUV A;  3JVX A;  2GD9 A;  1S3W A;  1RX8 A;  1JOM A;  3KJS A;  4HOG A;  4RGC A;  4I13 A;  3KJR A;  3CL9 A;  1DG7 A;  1RF7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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