1HICA

The nmr solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
51
structure length
51
Chain Sequence
VVYTDCTESGQNLCLCEGSNVCGQGNKCILGSDGEKNQCVTGEGTPKPQSH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hirudin
molecule keywords HIRUDIN VARIANT
publication title Nuclear magnetic resonance solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain.
pubmed doi rcsb
source organism Hirudo medicinalis
total genus 6
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 1992-04-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.10.10 Mainly Beta Distorted Sandwich Thrombin Inhibitor (Hirudin); Chain I Thrombin Inhibitor (Hirudin), subunit I 1hicA00
4MLFD 5HIRA 1HICA 4HTCI 6HIRA 4HIRA 1E0FI 1HRTI 2PW8I 2JOOA 2HIRA
chains in the Genus database with same CATH superfamily
4MLFD 5HIRA 1HICA 4HTCI 6HIRA 4HIRA 1E0FI 1HRTI 2PW8I 2JOOA 2HIRA
chains in the Genus database with same CATH topology
4MLFD 5HIRA 1HICA 4HTCI 6HIRA 4HIRA 1E0FI 1HRTI 2PW8I 2JOOA 2HIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MLF D;  5HIR A;  1HIC A;  4HTC I;  6HIR A;  4HIR A;  1E0F I;  1HRT I;  2PW8 I;  2JOO A;  2HIR A; 
#chains in the Genus database with same CATH topology
 4MLF D;  5HIR A;  1HIC A;  4HTC I;  6HIR A;  4HIR A;  1E0F I;  1HRT I;  2PW8 I;  2JOO A;  2HIR A; 
#chains in the Genus database with same CATH homology
 4MLF D;  5HIR A;  1HIC A;  4HTC I;  6HIR A;  4HIR A;  1E0F I;  1HRT I;  2PW8 I;  2JOO A;  2HIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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