1IGLA

Solution structure of human insulin-like growth factor ii relationship to receptor and binding protein interactions
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR II
publication title Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
pubmed rcsb
source organism Homo sapiens
total genus 11
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 1994-12-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1iglA00
2KJIA 1TGRA 1H02B 2JZQA 1GZYB 3KR3D 1ZEIA 2L29B 3LRIA 2DSRI 1WQJI 5L3LA 1BQTA 2DSPI 1B9GA 5L3NA 6INSE 5L3MA 1H59A 2KQPA 1GZRB 2DSQC 1GZZB 1PMXA 1SJUA 4XSSB 2LWZA 1IGLA 2GF1A 1EFEA 1IMXA 3GF1A
chains in the Genus database with same CATH superfamily
2KJIA 1TGRA 2L14B 1H02B 2JZQA 1GZYB 3KR3D 1ZEIA 2L29B 3LRIA 2DSRI 3F2DA 1WQJI 5L3LA 1BQTA 2DSPI 1B9GA 5L3NA 6INSE 5L3MA 3F2CA 1H59A 2KQPA 1GZRB 2DSQC 1GZZB 1PMXA 1SJUA 3F2BA 4XSSB 2LWZA 1IGLA 2GF1A 1EFEA 1IMXA 3GF1A
chains in the Genus database with same CATH topology
2KJIA 1TGRA 1H02B 2JZQA 1GZYB 3KR3D 1ZEIA 2L29B 3LRIA 2DSRI 1WQJI 5L3LA 1BQTA 2DSPI 1B9GA 5L3NA 6INSE 5L3MA 1H59A 2KQPA 1GZRB 2DSQC 1GZZB 1PMXA 1SJUA 4XSSB 2LWZA 1IGLA 2GF1A 1EFEA 1IMXA 3GF1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KJI A;  1TGR A;  1H02 B;  2JZQ A;  1GZY B;  3KR3 D;  1ZEI A;  2L29 B;  3LRI A;  2DSR I;  1WQJ I;  5L3L A;  1BQT A;  2DSP I;  1B9G A;  5L3N A;  6INS E;  5L3M A;  1H59 A;  2KQP A;  1GZR B;  2DSQ C;  1GZZ B;  1PMX A;  1SJU A;  4XSS B;  2LWZ A;  1IGL A;  2GF1 A;  1EFE A;  1IMX A;  3GF1 A; 
#chains in the Genus database with same CATH topology
 2KJI A;  1TGR A;  2L14 B;  1H02 B;  2JZQ A;  1GZY B;  3KR3 D;  1ZEI A;  2L29 B;  3LRI A;  2DSR I;  3F2D A;  1WQJ I;  5L3L A;  1BQT A;  2DSP I;  1B9G A;  5L3N A;  6INS E;  5L3M A;  3F2C A;  1H59 A;  2KQP A;  1GZR B;  2DSQ C;  1GZZ B;  1PMX A;  1SJU A;  3F2B A;  4XSS B;  2LWZ A;  1IGL A;  2GF1 A;  1EFE A;  1IMX A;  3GF1 A; 
#chains in the Genus database with same CATH homology
 2KJI A;  1TGR A;  1H02 B;  2JZQ A;  1GZY B;  3KR3 D;  1ZEI A;  2L29 B;  3LRI A;  2DSR I;  1WQJ I;  5L3L A;  1BQT A;  2DSP I;  1B9G A;  5L3N A;  6INS E;  5L3M A;  1H59 A;  2KQP A;  1GZR B;  2DSQ C;  1GZZ B;  1PMX A;  1SJU A;  4XSS B;  2LWZ A;  1IGL A;  2GF1 A;  1EFE A;  1IMX A;  3GF1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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