1ITVA

Dimeric form of the haemopexin domain of mmp9
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
195
structure length
195
Chain Sequence
DDACNVNIFDAIAEIGNQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEEPLSKKLFFFSGRQVWVYTGASVLGPRRLDKLGLGADVAQVTGALRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGVPLDTHDVFQFREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDILQCPED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords MMP9
publication title Structural basis of the adaptive molecular recognition by MMP9.
pubmed doi rcsb
source organism Homo sapiens
total genus 31
structure length 195
sequence length 195
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2002-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 1itvA00
1ITVA 4RT6B 4OEIA 4AUOA 3BA0A 1GENA 2MQSA 1PEXA 4YEHA 1CK7A 2CLTA 1FBLA 3C7XA 1HXNA 4FVLA 2JXYA 3OYOA 4G0DA 4HSDA 1QJSA 4FU4A 1SU3A 3LP9A 4LL2A 3V6NA 1QHUA 1GXDA 3S18A 1RTGA
chains in the Genus database with same CATH superfamily
1ITVA 4RT6B 4OEIA 4AUOA 3BA0A 1GENA 2MQSA 1PEXA 4YEHA 1CK7A 2CLTA 1FBLA 3C7XA 1HXNA 4FVLA 2JXYA 3OYOA 4G0DA 4HSDA 1QJSA 4FU4A 1SU3A 3LP9A 4LL2A 3V6NA 1QHUA 1GXDA 3S18A 1RTGA
chains in the Genus database with same CATH topology
1ITVA 4RT6B 4OEIA 4AUOA 3BA0A 1GENA 2MQSA 1PEXA 4YEHA 1CK7A 2CLTA 1FBLA 3C7XA 1HXNA 4FVLA 2JXYA 3OYOA 4G0DA 4HSDA 1QJSA 4FU4A 1SU3A 3LP9A 4LL2A 3V6NA 1QHUA 1GXDA 3S18A 1RTGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ITV A;  4RT6 B;  4OEI A;  4AUO A;  3BA0 A;  1GEN A;  2MQS A;  1PEX A;  4YEH A;  1CK7 A;  2CLT A;  1FBL A;  3C7X A;  1HXN A;  4FVL A;  2JXY A;  3OYO A;  4G0D A;  4HSD A;  1QJS A;  4FU4 A;  1SU3 A;  3LP9 A;  4LL2 A;  3V6N A;  1QHU A;  1GXD A;  3S18 A;  1RTG A; 
#chains in the Genus database with same CATH topology
 1ITV A;  4RT6 B;  4OEI A;  4AUO A;  3BA0 A;  1GEN A;  2MQS A;  1PEX A;  4YEH A;  1CK7 A;  2CLT A;  1FBL A;  3C7X A;  1HXN A;  4FVL A;  2JXY A;  3OYO A;  4G0D A;  4HSD A;  1QJS A;  4FU4 A;  1SU3 A;  3LP9 A;  4LL2 A;  3V6N A;  1QHU A;  1GXD A;  3S18 A;  1RTG A; 
#chains in the Genus database with same CATH homology
 1ITV A;  4RT6 B;  4OEI A;  4AUO A;  3BA0 A;  1GEN A;  2MQS A;  1PEX A;  4YEH A;  1CK7 A;  2CLT A;  1FBL A;  3C7X A;  1HXN A;  4FVL A;  2JXY A;  3OYO A;  4G0D A;  4HSD A;  1QJS A;  4FU4 A;  1SU3 A;  3LP9 A;  4LL2 A;  3V6N A;  1QHU A;  1GXD A;  3S18 A;  1RTG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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