1K2MA

Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide derived from rad9
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Protein Kinase SPK1
total genus 24
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1k2mA00
2JKDA 3I6WA 1FHRA 2FF4A 2KB4A 1R21A 1UHTA 3VA4A 3UOTA 4G2SA 2PIEA 2BRFA 1FHQA 1K2MA 3KT9A 2EH0A 2AFFA 1J4LA 2KFUA 3PO8A 3UNNA 2JQJA 4EJQA 3OUNA 4EGXA 3ELSA 1UJXA 2FEZA 1QU5A 3I0NA 2W3OA 2CSWA 2KB3A 1J4PA 5E50A 1J4OA 3UNMA 1GXCA 3I6UA 1K3QA 3VPYA 1LGPA 3HUEA 1G3GA 4A0EA 1YJ5C 3ELVA 3UV0A 3UN0A 1WLNA 3GQSA 5A8IA 2XT9B 2JQLA 3VA1A 2LC1A 2A0TA 1G6GA 3UMZA 2G1LA 1WV3A 2KKLA 2JQIA 1YJMA 4JONA 1DMZA 3MDBA 5DJOA 4QCJA 3FM8A 2JPEA 1K2NA 1LGQA 3HUFA 3POAA 1K3NA 1K3JA 3HX1A 3I0MA 4H87A 1J4KA 1J4QA 4D9VA 1MZKA
chains in the Genus database with same CATH superfamily
2JKDA 2XXSA 2AN1A 2I2AA 3I6WA 1FHRA 2FF4A 2KB4A 1KHXA 5C4VA 5JEOA 1R21A 1Y3HA 3V8PA 1UHTA 3VA4A 3UOTA 1MJSA 4G2SA 1U7FB 2PIEA 2BONA 2QVLA 2BRFA 1FHQA 1U0RA 3KT9A 1K2MA 1Z0ZA 1Z0SA 3PFNA 2EH0A 2AFFA 3DSHA 1J4LA 5DHQA 2KFUA 3PO8A 4L02A 3UNNA 2JQJA 4R9PA 3V7UA 4EJQA 3OUNA 4EGXA 1U0TA 3V8RA 3T5PA 3ELSA 5EJHA 1UJXA 2FEZA 4HAOA 5EJGA 5JEMA 2I1WA 1MK2A 1QU5A 2JGRA 3A77A 1ZOQA 3I0NA 2I2CA 3VZCA 4JIWD 3V8QA 2W3OA 2CSWA 2KB3A 1J4PA 4KU0D 5BVIA 5DHTA 5EJFA 5E50A 1J4OA 2I2BA 3UNMA 1GXCA 3V7WA 3I6UA 3V8NA 1U7VA 1Z0UA 5DHUA 3DITA 1LGPA 3HUEA 3VPYA 3V7YA 1K3QA 1G3GA 4A0EA 1YJ5C 3VZBA 3ELVA 3UV0A 4WERA 4WRRA 3UN0A 1WLNA 3GQSA 5A8IA 3AFOA 1U7FA 2Q5FA 2XT9B 2JQLA 4JIVD 3VA1A 2LC1A 1Y3IA 4V24A 2A0TA 5EJIA 5JEJA 2I2DA 1G6GA 1YT5A 3UMZA 2I2FA 5DHSA 5JERA 3GMJA 2G1LA 1WV3A 2KKLA 2JQIA 1SUWA 1YJMA 1MR1A 3V8MA 4JONA 5JELA 1DMZA 3MDBA 5DJOA 4QCJA 3FM8A 2JPEA 3V80A 1K2NA 1J2FA 5JEKA 1LGQA 3HUFA 3POAA 1K3NA 1K3JA 1KHUA 2QV7A 3HX1A 3S40A 3VZDA 2I29A 5DHPA 2P1RA 5DHRA 1QWTA 3I0MA 4H87A 1J4KA 1J4QA 4A4YA 1DD1A 1YGSA 4D9VA 1MZKA 4DY6A 1G88A 1U7VB 1DEVA
chains in the Genus database with same CATH topology
2JKDA 2XXSA 3I6WA 1FHRA 2FF4A 2KB4A 1KHXA 5C4VA 5JEOA 1R21A 1UHTA 3VA4A 3UOTA 1MJSA 4G2SA 1U7FB 2PIEA 2BONA 2QVLA 2BRFA 1FHQA 1K2MA 3KT9A 2EH0A 2AFFA 3DSHA 1J4LA 2KFUA 3PO8A 4L02A 3UNNA 2JQJA 4R9PA 4EJQA 3OUNA 4EGXA 3T5PA 3ELSA 1UJXA 2FEZA 5JEMA 1MK2A 1QU5A 2JGRA 3A77A 1ZOQA 3I0NA 3VZCA 4JIWD 2W3OA 2CSWA 2KB3A 1J4PA 4KU0D 5BVIA 5E50A 1J4OA 3UNMA 1GXCA 3I6UA 1U7VA 1K3QA 3DITA 1LGPA 3HUEA 3VPYA 1G3GA 4A0EA 1YJ5C 3VZBA 3ELVA 3UV0A 4WERA 4WRRA 3UN0A 1WLNA 3GQSA 5A8IA 1U7FA 2XT9B 2JQLA 4JIVD 3VA1A 2LC1A 4V24A 2A0TA 5JEJA 1G6GA 3UMZA 5JERA 3GMJA 2G1LA 1WV3A 2KKLA 2JQIA 1YJMA 1MR1A 4JONA 5JELA 1DMZA 3MDBA 5DJOA 4QCJA 3FM8A 2JPEA 1K2NA 1J2FA 5JEKA 1LGQA 3HUFA 3POAA 1K3NA 1K3JA 1KHUA 2QV7A 3HX1A 3S40A 3VZDA 2P1RA 1QWTA 3I0MA 4H87A 1J4KA 1J4QA 4A4YA 1DD1A 1YGSA 4D9VA 1MZKA 1G88A 1U7VB 1DEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JKD A;  3I6W A;  1FHR A;  2FF4 A;  2KB4 A;  1R21 A;  1UHT A;  3VA4 A;  3UOT A;  4G2S A;  2PIE A;  2BRF A;  1FHQ A;  1K2M A;  3KT9 A;  2EH0 A;  2AFF A;  1J4L A;  2KFU A;  3PO8 A;  3UNN A;  2JQJ A;  4EJQ A;  3OUN A;  4EGX A;  3ELS A;  1UJX A;  2FEZ A;  1QU5 A;  3I0N A;  2W3O A;  2CSW A;  2KB3 A;  1J4P A;  5E50 A;  1J4O A;  3UNM A;  1GXC A;  3I6U A;  1K3Q A;  3VPY A;  1LGP A;  3HUE A;  1G3G A;  4A0E A;  1YJ5 C;  3ELV A;  3UV0 A;  3UN0 A;  1WLN A;  3GQS A;  5A8I A;  2XT9 B;  2JQL A;  3VA1 A;  2LC1 A;  2A0T A;  1G6G A;  3UMZ A;  2G1L A;  1WV3 A;  2KKL A;  2JQI A;  1YJM A;  4JON A;  1DMZ A;  3MDB A;  5DJO A;  4QCJ A;  3FM8 A;  2JPE A;  1K2N A;  1LGQ A;  3HUF A;  3POA A;  1K3N A;  1K3J A;  3HX1 A;  3I0M A;  4H87 A;  1J4K A;  1J4Q A;  4D9V A;  1MZK A; 
#chains in the Genus database with same CATH topology
 2JKD A;  2XXS A;  2AN1 A;  2I2A A;  3I6W A;  1FHR A;  2FF4 A;  2KB4 A;  1KHX A;  5C4V A;  5JEO A;  1R21 A;  1Y3H A;  3V8P A;  1UHT A;  3VA4 A;  3UOT A;  1MJS A;  4G2S A;  1U7F B;  2PIE A;  2BON A;  2QVL A;  2BRF A;  1FHQ A;  1U0R A;  3KT9 A;  1K2M A;  1Z0Z A;  1Z0S A;  3PFN A;  2EH0 A;  2AFF A;  3DSH A;  1J4L A;  5DHQ A;  2KFU A;  3PO8 A;  4L02 A;  3UNN A;  2JQJ A;  4R9P A;  3V7U A;  4EJQ A;  3OUN A;  4EGX A;  1U0T A;  3V8R A;  3T5P A;  3ELS A;  5EJH A;  1UJX A;  2FEZ A;  4HAO A;  5EJG A;  5JEM A;  2I1W A;  1MK2 A;  1QU5 A;  2JGR A;  3A77 A;  1ZOQ A;  3I0N A;  2I2C A;  3VZC A;  4JIW D;  3V8Q A;  2W3O A;  2CSW A;  2KB3 A;  1J4P A;  4KU0 D;  5BVI A;  5DHT A;  5EJF A;  5E50 A;  1J4O A;  2I2B A;  3UNM A;  1GXC A;  3V7W A;  3I6U A;  3V8N A;  1U7V A;  1Z0U A;  5DHU A;  3DIT A;  1LGP A;  3HUE A;  3VPY A;  3V7Y A;  1K3Q A;  1G3G A;  4A0E A;  1YJ5 C;  3VZB A;  3ELV A;  3UV0 A;  4WER A;  4WRR A;  3UN0 A;  1WLN A;  3GQS A;  5A8I A;  3AFO A;  1U7F A;  2Q5F A;  2XT9 B;  2JQL A;  4JIV D;  3VA1 A;  2LC1 A;  1Y3I A;  4V24 A;  2A0T A;  5EJI A;  5JEJ A;  2I2D A;  1G6G A;  1YT5 A;  3UMZ A;  2I2F A;  5DHS A;  5JER A;  3GMJ A;  2G1L A;  1WV3 A;  2KKL A;  2JQI A;  1SUW A;  1YJM A;  1MR1 A;  3V8M A;  4JON A;  5JEL A;  1DMZ A;  3MDB A;  5DJO A;  4QCJ A;  3FM8 A;  2JPE A;  3V80 A;  1K2N A;  1J2F A;  5JEK A;  1LGQ A;  3HUF A;  3POA A;  1K3N A;  1K3J A;  1KHU A;  2QV7 A;  3HX1 A;  3S40 A;  3VZD A;  2I29 A;  5DHP A;  2P1R A;  5DHR A;  1QWT A;  3I0M A;  4H87 A;  1J4K A;  1J4Q A;  4A4Y A;  1DD1 A;  1YGS A;  4D9V A;  1MZK A;  4DY6 A;  1G88 A;  1U7V B;  1DEV A; 
#chains in the Genus database with same CATH homology
 2JKD A;  2XXS A;  3I6W A;  1FHR A;  2FF4 A;  2KB4 A;  1KHX A;  5C4V A;  5JEO A;  1R21 A;  1UHT A;  3VA4 A;  3UOT A;  1MJS A;  4G2S A;  1U7F B;  2PIE A;  2BON A;  2QVL A;  2BRF A;  1FHQ A;  1K2M A;  3KT9 A;  2EH0 A;  2AFF A;  3DSH A;  1J4L A;  2KFU A;  3PO8 A;  4L02 A;  3UNN A;  2JQJ A;  4R9P A;  4EJQ A;  3OUN A;  4EGX A;  3T5P A;  3ELS A;  1UJX A;  2FEZ A;  5JEM A;  1MK2 A;  1QU5 A;  2JGR A;  3A77 A;  1ZOQ A;  3I0N A;  3VZC A;  4JIW D;  2W3O A;  2CSW A;  2KB3 A;  1J4P A;  4KU0 D;  5BVI A;  5E50 A;  1J4O A;  3UNM A;  1GXC A;  3I6U A;  1U7V A;  1K3Q A;  3DIT A;  1LGP A;  3HUE A;  3VPY A;  1G3G A;  4A0E A;  1YJ5 C;  3VZB A;  3ELV A;  3UV0 A;  4WER A;  4WRR A;  3UN0 A;  1WLN A;  3GQS A;  5A8I A;  1U7F A;  2XT9 B;  2JQL A;  4JIV D;  3VA1 A;  2LC1 A;  4V24 A;  2A0T A;  5JEJ A;  1G6G A;  3UMZ A;  5JER A;  3GMJ A;  2G1L A;  1WV3 A;  2KKL A;  2JQI A;  1YJM A;  1MR1 A;  4JON A;  5JEL A;  1DMZ A;  3MDB A;  5DJO A;  4QCJ A;  3FM8 A;  2JPE A;  1K2N A;  1J2F A;  5JEK A;  1LGQ A;  3HUF A;  3POA A;  1K3N A;  1K3J A;  1KHU A;  2QV7 A;  3HX1 A;  3S40 A;  3VZD A;  2P1R A;  1QWT A;  3I0M A;  4H87 A;  1J4K A;  1J4Q A;  4A4Y A;  1DD1 A;  1YGS A;  4D9V A;  1MZK A;  1G88 A;  1U7V B;  1DEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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