1N86B

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
307
structure length
307
Chain Sequence
LYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrin alpha/alpha-E chain
total genus 84
structure length 307
sequence length 307
chains with identical sequence E
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86B02
2Q9IC 2JHKF 1Z3UA 2HLOC 4M7HA 1LWUC 3GHGC 2HODB 2H43C 2GY7A 1FZFC 1FZBB 2HPCB 1N86B 2J3OA 2XNXB 1LTJB 2HODC 3E1IC 4NYTA 2D39A 1N73B 2OYHC 1FICA 2HPCC 2FFDB 1N86C 2H43B 1FZFB 2JHLF 2J61B 1LT9C 2JHHC 2J3UA 1FZAB 2XNXC 1RE3B 1LTJC 2J1GA 1N73C 3E1IB 2FFDC 4R9TA 2OYHB 1FZCB 3H32C 1LT9B 1FZAC 1RE3C 1FZGB 3BVHC 2J5ZA 4R9JA 3FIBA 2J61A 4JZCA 1FZCC 2OYIB 1FIBA 1RF1C 4M7FA 2J60A 3H32B 1FZGC 2Z4EB 1JC9A 3BVHB 3HUSB 1RF0B 2OYIC 2J2PA 2Z4EC 1RF1B 2J0GA 1FZDA 3HUSC 1RF0C 2J3FA 2JHIF 4ZFGA 1FZEB 2J0YA 1FIDA 1RE4B 2J64A 2JHMF 1Z3SA 2FIBA 1M1JB 1FZEC 2Q9IB 1RE4C 2HLOB 1LWUB 2J3FD 2WNPF 1FZBC 4EPUA 2J0HA 2J3GA 4JYOX 1M1JC
chains in the Genus database with same CATH superfamily
2Q9IC 2JHKF 1Z3UA 2HLOC 4M7HA 1LWUC 3GHGC 2HODB 2H43C 2GY7A 1FZFC 1FZBB 2HPCB 1N86B 2J3OA 2XNXB 1LTJB 2HODC 3E1IC 4NYTA 3GHGB 2D39A 1N73B 2OYHC 1FICA 2HPCC 2FFDB 1N86C 2H43B 1FZFB 2JHLF 2J61B 1LT9C 2JHHC 2J3UA 1FZAB 2XNXC 1RE3B 1LTJC 2J1GA 1N73C 3E1IB 2FFDC 4R9TA 2OYHB 1FZCB 3H32C 1LT9B 1FZAC 1RE3C 1FZGB 3BVHC 2J5ZA 4R9JA 3FIBA 2J61A 4JZCA 1FZCC 2OYIB 1FIBA 1RF1C 4M7FA 2J60A 3H32B 1FZGC 2Z4EB 1JC9A 3BVHB 3HUSB 1RF0B 2OYIC 2J2PA 2Z4EC 1RF1B 2J0GA 1FZDA 3HUSC 1RF0C 2J3FA 2JHIF 4ZFGA 1FZEB 2J0YA 1FIDA 1RE4B 2J64A 2JHMF 1Z3SA 2FIBA 1M1JB 1FZEC 2Q9IB 1RE4C 2HLOB 1LWUB 2J3FD 2WNPF 1FZBC 4EPUA 2J0HA 2J3GA 4JYOX 1M1JC
chains in the Genus database with same CATH topology
2Q9IC 2JHKF 1Z3UA 2HLOC 4M7HA 1LWUC 3GHGC 2HODB 2H43C 2GY7A 1FZFC 1FZBB 2HPCB 1N86B 2J3OA 2XNXB 1LTJB 2HODC 3E1IC 4NYTA 2D39A 1N73B 2OYHC 1FICA 2HPCC 2FFDB 1N86C 2H43B 1FZFB 2JHLF 2J61B 1LT9C 2JHHC 2J3UA 1FZAB 2XNXC 1RE3B 1LTJC 2J1GA 1N73C 3E1IB 2FFDC 4R9TA 2OYHB 1FZCB 3H32C 1LT9B 1FZAC 1RE3C 1FZGB 3BVHC 2J5ZA 4R9JA 3FIBA 2J61A 4JZCA 1FZCC 2OYIB 1FIBA 1RF1C 4M7FA 2J60A 3H32B 1FZGC 2Z4EB 1JC9A 3BVHB 3HUSB 1RF0B 2OYIC 2J2PA 2Z4EC 1RF1B 2J0GA 1FZDA 3HUSC 1RF0C 2J3FA 2JHIF 4ZFGA 1FZEB 2J0YA 1FIDA 1RE4B 2J64A 2JHMF 1Z3SA 2FIBA 1M1JB 1FZEC 2Q9IB 1RE4C 2HLOB 1LWUB 2J3FD 2WNPF 1FZBC 4EPUA 2J0HA 2J3GA 4JYOX 1M1JC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q9I C;  2JHK F;  1Z3U A;  2HLO C;  4M7H A;  1LWU C;  3GHG C;  2HOD B;  2H43 C;  2GY7 A;  1FZF C;  1FZB B;  2HPC B;  1N86 B;  2J3O A;  2XNX B;  1LTJ B;  2HOD C;  3E1I C;  4NYT A;  2D39 A;  1N73 B;  2OYH C;  1FIC A;  2HPC C;  2FFD B;  1N86 C;  2H43 B;  1FZF B;  2JHL F;  2J61 B;  1LT9 C;  2JHH C;  2J3U A;  1FZA B;  2XNX C;  1RE3 B;  1LTJ C;  2J1G A;  1N73 C;  3E1I B;  2FFD C;  4R9T A;  2OYH B;  1FZC B;  3H32 C;  1LT9 B;  1FZA C;  1RE3 C;  1FZG B;  3BVH C;  2J5Z A;  4R9J A;  3FIB A;  2J61 A;  4JZC A;  1FZC C;  2OYI B;  1FIB A;  1RF1 C;  4M7F A;  2J60 A;  3H32 B;  1FZG C;  2Z4E B;  1JC9 A;  3BVH B;  3HUS B;  1RF0 B;  2OYI C;  2J2P A;  2Z4E C;  1RF1 B;  2J0G A;  1FZD A;  3HUS C;  1RF0 C;  2J3F A;  2JHI F;  4ZFG A;  1FZE B;  2J0Y A;  1FID A;  1RE4 B;  2J64 A;  2JHM F;  1Z3S A;  2FIB A;  1M1J B;  1FZE C;  2Q9I B;  1RE4 C;  2HLO B;  1LWU B;  2J3F D;  2WNP F;  1FZB C;  4EPU A;  2J0H A;  2J3G A;  4JYO X;  1M1J C; 
#chains in the Genus database with same CATH topology
 2Q9I C;  2JHK F;  1Z3U A;  2HLO C;  4M7H A;  1LWU C;  3GHG C;  2HOD B;  2H43 C;  2GY7 A;  1FZF C;  1FZB B;  2HPC B;  1N86 B;  2J3O A;  2XNX B;  1LTJ B;  2HOD C;  3E1I C;  4NYT A;  3GHG B;  2D39 A;  1N73 B;  2OYH C;  1FIC A;  2HPC C;  2FFD B;  1N86 C;  2H43 B;  1FZF B;  2JHL F;  2J61 B;  1LT9 C;  2JHH C;  2J3U A;  1FZA B;  2XNX C;  1RE3 B;  1LTJ C;  2J1G A;  1N73 C;  3E1I B;  2FFD C;  4R9T A;  2OYH B;  1FZC B;  3H32 C;  1LT9 B;  1FZA C;  1RE3 C;  1FZG B;  3BVH C;  2J5Z A;  4R9J A;  3FIB A;  2J61 A;  4JZC A;  1FZC C;  2OYI B;  1FIB A;  1RF1 C;  4M7F A;  2J60 A;  3H32 B;  1FZG C;  2Z4E B;  1JC9 A;  3BVH B;  3HUS B;  1RF0 B;  2OYI C;  2J2P A;  2Z4E C;  1RF1 B;  2J0G A;  1FZD A;  3HUS C;  1RF0 C;  2J3F A;  2JHI F;  4ZFG A;  1FZE B;  2J0Y A;  1FID A;  1RE4 B;  2J64 A;  2JHM F;  1Z3S A;  2FIB A;  1M1J B;  1FZE C;  2Q9I B;  1RE4 C;  2HLO B;  1LWU B;  2J3F D;  2WNP F;  1FZB C;  4EPU A;  2J0H A;  2J3G A;  4JYO X;  1M1J C; 
#chains in the Genus database with same CATH homology
 2Q9I C;  2JHK F;  1Z3U A;  2HLO C;  4M7H A;  1LWU C;  3GHG C;  2HOD B;  2H43 C;  2GY7 A;  1FZF C;  1FZB B;  2HPC B;  1N86 B;  2J3O A;  2XNX B;  1LTJ B;  2HOD C;  3E1I C;  4NYT A;  2D39 A;  1N73 B;  2OYH C;  1FIC A;  2HPC C;  2FFD B;  1N86 C;  2H43 B;  1FZF B;  2JHL F;  2J61 B;  1LT9 C;  2JHH C;  2J3U A;  1FZA B;  2XNX C;  1RE3 B;  1LTJ C;  2J1G A;  1N73 C;  3E1I B;  2FFD C;  4R9T A;  2OYH B;  1FZC B;  3H32 C;  1LT9 B;  1FZA C;  1RE3 C;  1FZG B;  3BVH C;  2J5Z A;  4R9J A;  3FIB A;  2J61 A;  4JZC A;  1FZC C;  2OYI B;  1FIB A;  1RF1 C;  4M7F A;  2J60 A;  3H32 B;  1FZG C;  2Z4E B;  1JC9 A;  3BVH B;  3HUS B;  1RF0 B;  2OYI C;  2J2P A;  2Z4E C;  1RF1 B;  2J0G A;  1FZD A;  3HUS C;  1RF0 C;  2J3F A;  2JHI F;  4ZFG A;  1FZE B;  2J0Y A;  1FID A;  1RE4 B;  2J64 A;  2JHM F;  1Z3S A;  2FIB A;  1M1J B;  1FZE C;  2Q9I B;  1RE4 C;  2HLO B;  1LWU B;  2J3F D;  2WNP F;  1FZB C;  4EPU A;  2J0H A;  2J3G A;  4JYO X;  1M1J C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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