1N86C

Crystal structure of human d-dimer from cross-linked fibrin complexed with gpr and ghrpldk peptide ligands.
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
295
structure length
295
Chain Sequence
EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords Fibrin alpha/alpha-E chain
total genus 76
structure length 295
sequence length 295
chains with identical sequence F
ec nomenclature
pdb deposition date 2002-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1n86C01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1n86C02
3H32B 1FZDA 1Z3SA 2HODC 2OYIB 1N86B 2J2PA 4ZFGA 3BVHB 2H43B 2J3UA 1FZEB 4NYTA 2J1GA 1RF0B 1RF1C 1FZBC 2OYHB 2HLOB 3E1IB 1JC9A 1FZCC 2HPCC 2Q9IB 4R9TA 2J3OA 2J61A 1RE3B 2J0HA 2FFDB 2JHIF 1LT9C 4R9JA 1LTJC 1RE4B 2JHKF 1N73B 3HUSB 4JYOX 4JZCA 1FZFC 2XNXC 1FZGB 1FIBA 1FZAB 3H32C 2OYIC 1N86C 2J61B 1M1JB 2J60A 3BVHC 2H43C 2J0YA 4M7HA 2HODB 2J3FD 1FZEC 1LWUC 2HLOC 3E1IC 2J64A 2JHMF 1RF1B 1FZBB 2Q9IC 3GHGC 2FIBA 1FZCB 2HPCB 2J3FA 2Z4EC 2J5ZA 1FIDA 1RE3C 2FFDC 1FICA 4EPUA 1RE4C 2J0GA 3FIBA 1Z3UA 1LT9B 1N73C 2D39A 3HUSC 1LTJB 1RF0C 1LWUB 2OYHC 2J3GA 4M7FA 1FZGC 1FZAC 2GY7A 1FZFB 2XNXB 2JHHC 2WNPF 2JHLF 2Z4EB 1M1JC
chains in the Genus database with same CATH superfamily
3H32B 1FZDA 1Z3SA 2HODC 2OYIB 1N86B 2J2PA 4ZFGA 3BVHB 2H43B 2J3UA 1FZEB 4NYTA 2J1GA 1RF0B 1RF1C 1FZBC 2OYHB 2HLOB 3E1IB 1JC9A 1FZCC 2HPCC 2Q9IB 4R9TA 3GHGB 2J3OA 2J61A 1RE3B 2J0HA 2FFDB 2JHIF 1LT9C 4R9JA 1LTJC 1RE4B 2JHKF 1N73B 3HUSB 4JYOX 4JZCA 1FZFC 2XNXC 1FZGB 1FIBA 1FZAB 3H32C 2OYIC 1N86C 2J61B 1M1JB 2J60A 3BVHC 2H43C 2J0YA 4M7HA 2HODB 2J3FD 1FZEC 1LWUC 2HLOC 3E1IC 2J64A 2JHMF 1RF1B 1FZBB 2Q9IC 3GHGC 2FIBA 1FZCB 2HPCB 2J3FA 2Z4EC 2J5ZA 1FIDA 1RE3C 2FFDC 1FICA 4EPUA 1RE4C 2J0GA 3FIBA 1Z3UA 1LT9B 1N73C 2D39A 3HUSC 1LTJB 1RF0C 1LWUB 2OYHC 2J3GA 4M7FA 1FZGC 1FZAC 2GY7A 1FZFB 2XNXB 2JHHC 2WNPF 2JHLF 2Z4EB 1M1JC
chains in the Genus database with same CATH topology
3H32B 1FZDA 1Z3SA 2HODC 2OYIB 1N86B 2J2PA 4ZFGA 3BVHB 2H43B 2J3UA 1FZEB 4NYTA 2J1GA 1RF0B 1RF1C 1FZBC 2OYHB 2HLOB 3E1IB 1JC9A 1FZCC 2HPCC 2Q9IB 4R9TA 2J3OA 2J61A 1RE3B 2J0HA 2FFDB 2JHIF 1LT9C 4R9JA 1LTJC 1RE4B 2JHKF 1N73B 3HUSB 4JYOX 4JZCA 1FZFC 2XNXC 1FZGB 1FIBA 1FZAB 3H32C 2OYIC 1N86C 2J61B 1M1JB 2J60A 3BVHC 2H43C 2J0YA 4M7HA 2HODB 2J3FD 1FZEC 1LWUC 2HLOC 3E1IC 2J64A 2JHMF 1RF1B 1FZBB 2Q9IC 3GHGC 2FIBA 1FZCB 2HPCB 2J3FA 2Z4EC 2J5ZA 1FIDA 1RE3C 2FFDC 1FICA 4EPUA 1RE4C 2J0GA 3FIBA 1Z3UA 1LT9B 1N73C 2D39A 3HUSC 1LTJB 1RF0C 1LWUB 2OYHC 2J3GA 4M7FA 1FZGC 1FZAC 2GY7A 1FZFB 2XNXB 2JHHC 2WNPF 2JHLF 2Z4EB 1M1JC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H32 B;  1FZD A;  1Z3S A;  2HOD C;  2OYI B;  1N86 B;  2J2P A;  4ZFG A;  3BVH B;  2H43 B;  2J3U A;  1FZE B;  4NYT A;  2J1G A;  1RF0 B;  1RF1 C;  1FZB C;  2OYH B;  2HLO B;  3E1I B;  1JC9 A;  1FZC C;  2HPC C;  2Q9I B;  4R9T A;  2J3O A;  2J61 A;  1RE3 B;  2J0H A;  2FFD B;  2JHI F;  1LT9 C;  4R9J A;  1LTJ C;  1RE4 B;  2JHK F;  1N73 B;  3HUS B;  4JYO X;  4JZC A;  1FZF C;  2XNX C;  1FZG B;  1FIB A;  1FZA B;  3H32 C;  2OYI C;  1N86 C;  2J61 B;  1M1J B;  2J60 A;  3BVH C;  2H43 C;  2J0Y A;  4M7H A;  2HOD B;  2J3F D;  1FZE C;  1LWU C;  2HLO C;  3E1I C;  2J64 A;  2JHM F;  1RF1 B;  1FZB B;  2Q9I C;  3GHG C;  2FIB A;  1FZC B;  2HPC B;  2J3F A;  2Z4E C;  2J5Z A;  1FID A;  1RE3 C;  2FFD C;  1FIC A;  4EPU A;  1RE4 C;  2J0G A;  3FIB A;  1Z3U A;  1LT9 B;  1N73 C;  2D39 A;  3HUS C;  1LTJ B;  1RF0 C;  1LWU B;  2OYH C;  2J3G A;  4M7F A;  1FZG C;  1FZA C;  2GY7 A;  1FZF B;  2XNX B;  2JHH C;  2WNP F;  2JHL F;  2Z4E B;  1M1J C; 
#chains in the Genus database with same CATH topology
 3H32 B;  1FZD A;  1Z3S A;  2HOD C;  2OYI B;  1N86 B;  2J2P A;  4ZFG A;  3BVH B;  2H43 B;  2J3U A;  1FZE B;  4NYT A;  2J1G A;  1RF0 B;  1RF1 C;  1FZB C;  2OYH B;  2HLO B;  3E1I B;  1JC9 A;  1FZC C;  2HPC C;  2Q9I B;  4R9T A;  3GHG B;  2J3O A;  2J61 A;  1RE3 B;  2J0H A;  2FFD B;  2JHI F;  1LT9 C;  4R9J A;  1LTJ C;  1RE4 B;  2JHK F;  1N73 B;  3HUS B;  4JYO X;  4JZC A;  1FZF C;  2XNX C;  1FZG B;  1FIB A;  1FZA B;  3H32 C;  2OYI C;  1N86 C;  2J61 B;  1M1J B;  2J60 A;  3BVH C;  2H43 C;  2J0Y A;  4M7H A;  2HOD B;  2J3F D;  1FZE C;  1LWU C;  2HLO C;  3E1I C;  2J64 A;  2JHM F;  1RF1 B;  1FZB B;  2Q9I C;  3GHG C;  2FIB A;  1FZC B;  2HPC B;  2J3F A;  2Z4E C;  2J5Z A;  1FID A;  1RE3 C;  2FFD C;  1FIC A;  4EPU A;  1RE4 C;  2J0G A;  3FIB A;  1Z3U A;  1LT9 B;  1N73 C;  2D39 A;  3HUS C;  1LTJ B;  1RF0 C;  1LWU B;  2OYH C;  2J3G A;  4M7F A;  1FZG C;  1FZA C;  2GY7 A;  1FZF B;  2XNX B;  2JHH C;  2WNP F;  2JHL F;  2Z4E B;  1M1J C; 
#chains in the Genus database with same CATH homology
 3H32 B;  1FZD A;  1Z3S A;  2HOD C;  2OYI B;  1N86 B;  2J2P A;  4ZFG A;  3BVH B;  2H43 B;  2J3U A;  1FZE B;  4NYT A;  2J1G A;  1RF0 B;  1RF1 C;  1FZB C;  2OYH B;  2HLO B;  3E1I B;  1JC9 A;  1FZC C;  2HPC C;  2Q9I B;  4R9T A;  2J3O A;  2J61 A;  1RE3 B;  2J0H A;  2FFD B;  2JHI F;  1LT9 C;  4R9J A;  1LTJ C;  1RE4 B;  2JHK F;  1N73 B;  3HUS B;  4JYO X;  4JZC A;  1FZF C;  2XNX C;  1FZG B;  1FIB A;  1FZA B;  3H32 C;  2OYI C;  1N86 C;  2J61 B;  1M1J B;  2J60 A;  3BVH C;  2H43 C;  2J0Y A;  4M7H A;  2HOD B;  2J3F D;  1FZE C;  1LWU C;  2HLO C;  3E1I C;  2J64 A;  2JHM F;  1RF1 B;  1FZB B;  2Q9I C;  3GHG C;  2FIB A;  1FZC B;  2HPC B;  2J3F A;  2Z4E C;  2J5Z A;  1FID A;  1RE3 C;  2FFD C;  1FIC A;  4EPU A;  1RE4 C;  2J0G A;  3FIB A;  1Z3U A;  1LT9 B;  1N73 C;  2D39 A;  3HUS C;  1LTJ B;  1RF0 C;  1LWU B;  2OYH C;  2J3G A;  4M7F A;  1FZG C;  1FZA C;  2GY7 A;  1FZF B;  2XNX B;  2JHH C;  2WNP F;  2JHL F;  2Z4E B;  1M1J C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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