1NAGA

Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of f22a, y23a, n43g, and f45a
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
56
structure length
56
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRGNFKSAEDCMRTCG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
pubmed rcsb
molecule tags Serine protease inhibitor
source organism Bos taurus
molecule keywords BOVINE PANCREATIC TRYPSIN INHIBITOR
total genus 7
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1992-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1nagA00
2ZVXA 1P2OB 2LFKA 1LD6A 3BTTI 3BTEI 1AAPA 4U32X 1OA55 3L3TE 5PTIA 4DG4C 9PTIA 1KTHA 3LDIA 4WWYC 2PTCI 3TGJI 1TPAI 4NTWB 1TAPA 2TPII 2FTMB 3TGKI 4DTGK 1Y62A 2J6DA 1P2MB 3BTWI 1BPTA 3UIRC 3AUDA 1B0CA 4WXVC 1DENA 1OA65 1BTHP 2FI5I 1BIKA 1CO7I 4U30W 3TPII 3WNYA 3T62D 1YC0I 5C67C 3OFWA 4NTXB 1TCPA 1P2KI 1BUNB 2KCRA 2M99A 5JB6A 3UOUB 1P2JI 3BYBA 1D0DA 2FI3I 1G6XA 2ZJXA 1NAGA 1BTIA 3P92E 2IJOI 1KIGI 4BD9B 1PITA 3D65I 1SHPA 3BTKI 2FTLI 2LFLA 5JB5A 1JV8A 3BTGI 1BHCA 3FP6I 2FI4I 1BF0A 1QLQA 2CA7A 5JB4A 7PTIA 8PTIA 2TGPI 3TGII 1P2NB 2UUXA 3P95E 2R9PE 1BRCI 1FY8I 4Y0ZI 1MTND 3AUCA 3GYMI 1D0DB 1UUBA 2ODYE 4ISNB 1FANA 1K6UA 3BTFI 2UUYB 1TAWB 2RA3C 1P2II 1CBWD 1LD5A 1UUAA 2DDIA 1ZR0B 4PTIA 3U1JE 1ADZA 1F7ZI 3AUBA 3AUGA 1CA0D 4ISOB 1BZXI 1IRHA 1BPIA 3LDMA 4BQDA 2HEXA 1KNTA 1T7CB 2JOTA 4TPII 1F5RI 4ISLB 1KUNA 1YLCB 2M01A 3AUHA 1EAWB 1DTKA 3OTJI 1DTXA 1TFXC 3L33E 3M7QB 1DEMA 1ZJDB 2W8XA 6PTIA 3BTHI 3FP7J 4NTYB 3AUIA 1AALA 1EJMB 1T8MB 3FP8I 5JB7A 3BTDI 1FAKI 1YKTB 4BNRI 1YLDB 3BTQI 1TOCR 2KNTA 4Y10I 1BRBI 1T8OB 1JV9A 3CI7A 3LDJA 1BZ5A 2KAII 4Y11I 1T8LB 1JC6A 1T8NB 2DDJA 3AUEA 1P2QB 3BTMI 4Y0YI
chains in the Genus database with same CATH superfamily
2ZVXA 1P2OB 2LFKA 1LD6A 3BTTI 3BTEI 1AAPA 4U32X 1OA55 3L3TE 5PTIA 4DG4C 9PTIA 1KTHA 3LDIA 4WWYC 2PTCI 3TGJI 1TPAI 4NTWB 1TAPA 2TPII 2FTMB 3TGKI 4DTGK 1Y62A 2J6DA 1P2MB 3BTWI 1BPTA 3UIRC 3AUDA 1B0CA 4WXVC 1DENA 1OA65 1BTHP 2FI5I 1BIKA 1CO7I 4U30W 3TPII 3WNYA 3T62D 1YC0I 5C67C 3OFWA 4NTXB 1TCPA 1P2KI 1BUNB 2KCRA 2M99A 5JB6A 3UOUB 1P2JI 3BYBA 1D0DA 2FI3I 1G6XA 2ZJXA 1NAGA 1BTIA 3P92E 2IJOI 1KIGI 4BD9B 1PITA 3D65I 1SHPA 3BTKI 2FTLI 2LFLA 5JB5A 1JV8A 3BTGI 1BHCA 3FP6I 2FI4I 1BF0A 1QLQA 2CA7A 5JB4A 7PTIA 8PTIA 2TGPI 3TGII 1P2NB 2UUXA 3P95E 2R9PE 1BRCI 1FY8I 4Y0ZI 1MTND 3AUCA 3GYMI 1D0DB 1UUBA 2ODYE 4ISNB 1FANA 1K6UA 3BTFI 2UUYB 1TAWB 2RA3C 1P2II 1CBWD 1LD5A 1UUAA 2DDIA 1ZR0B 4PTIA 3U1JE 1ADZA 1F7ZI 3AUBA 3AUGA 1CA0D 4ISOB 1BZXI 1IRHA 1BPIA 3LDMA 4BQDA 2HEXA 1KNTA 1T7CB 2JOTA 4TPII 1F5RI 4ISLB 1KUNA 1YLCB 2M01A 3AUHA 1EAWB 1DTKA 3OTJI 1DTXA 1TFXC 3L33E 3M7QB 1DEMA 1ZJDB 2W8XA 6PTIA 3BTHI 3FP7J 4NTYB 3AUIA 1AALA 1EJMB 1T8MB 3FP8I 5JB7A 3BTDI 1FAKI 1YKTB 4BNRI 1YLDB 3BTQI 1TOCR 2KNTA 4Y10I 1BRBI 1T8OB 1JV9A 3CI7A 3LDJA 1BZ5A 2KAII 4Y11I 1T8LB 1JC6A 1T8NB 2DDJA 3AUEA 1P2QB 3BTMI 4Y0YI
chains in the Genus database with same CATH topology
2ZVXA 1P2OB 2LFKA 1LD6A 3BTTI 3BTEI 1AAPA 4U32X 1OA55 3L3TE 5PTIA 4DG4C 9PTIA 1KTHA 3LDIA 4WWYC 2PTCI 3TGJI 1TPAI 4NTWB 1TAPA 2TPII 2FTMB 3TGKI 4DTGK 1Y62A 2J6DA 1P2MB 3BTWI 1BPTA 3UIRC 3AUDA 1B0CA 4WXVC 1DENA 1OA65 1BTHP 2FI5I 1BIKA 1CO7I 4U30W 3TPII 3WNYA 3T62D 1YC0I 5C67C 3OFWA 4NTXB 1TCPA 1P2KI 1BUNB 2KCRA 2M99A 5JB6A 3UOUB 1P2JI 3BYBA 1D0DA 2FI3I 1G6XA 2ZJXA 1NAGA 1BTIA 3P92E 2IJOI 1KIGI 4BD9B 1PITA 3D65I 1SHPA 3BTKI 2FTLI 2LFLA 5JB5A 1JV8A 3BTGI 1BHCA 3FP6I 2FI4I 1BF0A 1QLQA 2CA7A 5JB4A 7PTIA 8PTIA 2TGPI 3TGII 1P2NB 2UUXA 3P95E 2R9PE 1BRCI 1FY8I 4Y0ZI 1MTND 3AUCA 3GYMI 1D0DB 1UUBA 2ODYE 4ISNB 1FANA 1K6UA 3BTFI 2UUYB 1TAWB 2RA3C 1P2II 1CBWD 1LD5A 1UUAA 2DDIA 1ZR0B 4PTIA 3U1JE 1ADZA 1F7ZI 3AUBA 3AUGA 1CA0D 4ISOB 1BZXI 1IRHA 1BPIA 3LDMA 4BQDA 2HEXA 1KNTA 1T7CB 2JOTA 4TPII 1F5RI 4ISLB 1KUNA 1YLCB 2M01A 3AUHA 1EAWB 1DTKA 3OTJI 1DTXA 1TFXC 3L33E 3M7QB 1DEMA 1ZJDB 2W8XA 6PTIA 3BTHI 3FP7J 4NTYB 3AUIA 1AALA 1EJMB 1T8MB 3FP8I 5JB7A 3BTDI 1FAKI 1YKTB 4BNRI 1YLDB 3BTQI 1TOCR 2KNTA 4Y10I 1BRBI 1T8OB 1JV9A 3CI7A 3LDJA 1BZ5A 2KAII 4Y11I 1T8LB 1JC6A 1T8NB 2DDJA 3AUEA 1P2QB 3BTMI 4Y0YI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVX A;  1P2O B;  2LFK A;  1LD6 A;  3BTT I;  3BTE I;  1AAP A;  4U32 X;  1OA5 5;  3L3T E;  5PTI A;  4DG4 C;  9PTI A;  1KTH A;  3LDI A;  4WWY C;  2PTC I;  3TGJ I;  1TPA I;  4NTW B;  1TAP A;  2TPI I;  2FTM B;  3TGK I;  4DTG K;  1Y62 A;  2J6D A;  1P2M B;  3BTW I;  1BPT A;  3UIR C;  3AUD A;  1B0C A;  4WXV C;  1DEN A;  1OA6 5;  1BTH P;  2FI5 I;  1BIK A;  1CO7 I;  4U30 W;  3TPI I;  3WNY A;  3T62 D;  1YC0 I;  5C67 C;  3OFW A;  4NTX B;  1TCP A;  1P2K I;  1BUN B;  2KCR A;  2M99 A;  5JB6 A;  3UOU B;  1P2J I;  3BYB A;  1D0D A;  2FI3 I;  1G6X A;  2ZJX A;  1NAG A;  1BTI A;  3P92 E;  2IJO I;  1KIG I;  4BD9 B;  1PIT A;  3D65 I;  1SHP A;  3BTK I;  2FTL I;  2LFL A;  5JB5 A;  1JV8 A;  3BTG I;  1BHC A;  3FP6 I;  2FI4 I;  1BF0 A;  1QLQ A;  2CA7 A;  5JB4 A;  7PTI A;  8PTI A;  2TGP I;  3TGI I;  1P2N B;  2UUX A;  3P95 E;  2R9P E;  1BRC I;  1FY8 I;  4Y0Z I;  1MTN D;  3AUC A;  3GYM I;  1D0D B;  1UUB A;  2ODY E;  4ISN B;  1FAN A;  1K6U A;  3BTF I;  2UUY B;  1TAW B;  2RA3 C;  1P2I I;  1CBW D;  1LD5 A;  1UUA A;  2DDI A;  1ZR0 B;  4PTI A;  3U1J E;  1ADZ A;  1F7Z I;  3AUB A;  3AUG A;  1CA0 D;  4ISO B;  1BZX I;  1IRH A;  1BPI A;  3LDM A;  4BQD A;  2HEX A;  1KNT A;  1T7C B;  2JOT A;  4TPI I;  1F5R I;  4ISL B;  1KUN A;  1YLC B;  2M01 A;  3AUH A;  1EAW B;  1DTK A;  3OTJ I;  1DTX A;  1TFX C;  3L33 E;  3M7Q B;  1DEM A;  1ZJD B;  2W8X A;  6PTI A;  3BTH I;  3FP7 J;  4NTY B;  3AUI A;  1AAL A;  1EJM B;  1T8M B;  3FP8 I;  5JB7 A;  3BTD I;  1FAK I;  1YKT B;  4BNR I;  1YLD B;  3BTQ I;  1TOC R;  2KNT A;  4Y10 I;  1BRB I;  1T8O B;  1JV9 A;  3CI7 A;  3LDJ A;  1BZ5 A;  2KAI I;  4Y11 I;  1T8L B;  1JC6 A;  1T8N B;  2DDJ A;  3AUE A;  1P2Q B;  3BTM I;  4Y0Y I; 
#chains in the Genus database with same CATH topology
 2ZVX A;  1P2O B;  2LFK A;  1LD6 A;  3BTT I;  3BTE I;  1AAP A;  4U32 X;  1OA5 5;  3L3T E;  5PTI A;  4DG4 C;  9PTI A;  1KTH A;  3LDI A;  4WWY C;  2PTC I;  3TGJ I;  1TPA I;  4NTW B;  1TAP A;  2TPI I;  2FTM B;  3TGK I;  4DTG K;  1Y62 A;  2J6D A;  1P2M B;  3BTW I;  1BPT A;  3UIR C;  3AUD A;  1B0C A;  4WXV C;  1DEN A;  1OA6 5;  1BTH P;  2FI5 I;  1BIK A;  1CO7 I;  4U30 W;  3TPI I;  3WNY A;  3T62 D;  1YC0 I;  5C67 C;  3OFW A;  4NTX B;  1TCP A;  1P2K I;  1BUN B;  2KCR A;  2M99 A;  5JB6 A;  3UOU B;  1P2J I;  3BYB A;  1D0D A;  2FI3 I;  1G6X A;  2ZJX A;  1NAG A;  1BTI A;  3P92 E;  2IJO I;  1KIG I;  4BD9 B;  1PIT A;  3D65 I;  1SHP A;  3BTK I;  2FTL I;  2LFL A;  5JB5 A;  1JV8 A;  3BTG I;  1BHC A;  3FP6 I;  2FI4 I;  1BF0 A;  1QLQ A;  2CA7 A;  5JB4 A;  7PTI A;  8PTI A;  2TGP I;  3TGI I;  1P2N B;  2UUX A;  3P95 E;  2R9P E;  1BRC I;  1FY8 I;  4Y0Z I;  1MTN D;  3AUC A;  3GYM I;  1D0D B;  1UUB A;  2ODY E;  4ISN B;  1FAN A;  1K6U A;  3BTF I;  2UUY B;  1TAW B;  2RA3 C;  1P2I I;  1CBW D;  1LD5 A;  1UUA A;  2DDI A;  1ZR0 B;  4PTI A;  3U1J E;  1ADZ A;  1F7Z I;  3AUB A;  3AUG A;  1CA0 D;  4ISO B;  1BZX I;  1IRH A;  1BPI A;  3LDM A;  4BQD A;  2HEX A;  1KNT A;  1T7C B;  2JOT A;  4TPI I;  1F5R I;  4ISL B;  1KUN A;  1YLC B;  2M01 A;  3AUH A;  1EAW B;  1DTK A;  3OTJ I;  1DTX A;  1TFX C;  3L33 E;  3M7Q B;  1DEM A;  1ZJD B;  2W8X A;  6PTI A;  3BTH I;  3FP7 J;  4NTY B;  3AUI A;  1AAL A;  1EJM B;  1T8M B;  3FP8 I;  5JB7 A;  3BTD I;  1FAK I;  1YKT B;  4BNR I;  1YLD B;  3BTQ I;  1TOC R;  2KNT A;  4Y10 I;  1BRB I;  1T8O B;  1JV9 A;  3CI7 A;  3LDJ A;  1BZ5 A;  2KAI I;  4Y11 I;  1T8L B;  1JC6 A;  1T8N B;  2DDJ A;  3AUE A;  1P2Q B;  3BTM I;  4Y0Y I; 
#chains in the Genus database with same CATH homology
 2ZVX A;  1P2O B;  2LFK A;  1LD6 A;  3BTT I;  3BTE I;  1AAP A;  4U32 X;  1OA5 5;  3L3T E;  5PTI A;  4DG4 C;  9PTI A;  1KTH A;  3LDI A;  4WWY C;  2PTC I;  3TGJ I;  1TPA I;  4NTW B;  1TAP A;  2TPI I;  2FTM B;  3TGK I;  4DTG K;  1Y62 A;  2J6D A;  1P2M B;  3BTW I;  1BPT A;  3UIR C;  3AUD A;  1B0C A;  4WXV C;  1DEN A;  1OA6 5;  1BTH P;  2FI5 I;  1BIK A;  1CO7 I;  4U30 W;  3TPI I;  3WNY A;  3T62 D;  1YC0 I;  5C67 C;  3OFW A;  4NTX B;  1TCP A;  1P2K I;  1BUN B;  2KCR A;  2M99 A;  5JB6 A;  3UOU B;  1P2J I;  3BYB A;  1D0D A;  2FI3 I;  1G6X A;  2ZJX A;  1NAG A;  1BTI A;  3P92 E;  2IJO I;  1KIG I;  4BD9 B;  1PIT A;  3D65 I;  1SHP A;  3BTK I;  2FTL I;  2LFL A;  5JB5 A;  1JV8 A;  3BTG I;  1BHC A;  3FP6 I;  2FI4 I;  1BF0 A;  1QLQ A;  2CA7 A;  5JB4 A;  7PTI A;  8PTI A;  2TGP I;  3TGI I;  1P2N B;  2UUX A;  3P95 E;  2R9P E;  1BRC I;  1FY8 I;  4Y0Z I;  1MTN D;  3AUC A;  3GYM I;  1D0D B;  1UUB A;  2ODY E;  4ISN B;  1FAN A;  1K6U A;  3BTF I;  2UUY B;  1TAW B;  2RA3 C;  1P2I I;  1CBW D;  1LD5 A;  1UUA A;  2DDI A;  1ZR0 B;  4PTI A;  3U1J E;  1ADZ A;  1F7Z I;  3AUB A;  3AUG A;  1CA0 D;  4ISO B;  1BZX I;  1IRH A;  1BPI A;  3LDM A;  4BQD A;  2HEX A;  1KNT A;  1T7C B;  2JOT A;  4TPI I;  1F5R I;  4ISL B;  1KUN A;  1YLC B;  2M01 A;  3AUH A;  1EAW B;  1DTK A;  3OTJ I;  1DTX A;  1TFX C;  3L33 E;  3M7Q B;  1DEM A;  1ZJD B;  2W8X A;  6PTI A;  3BTH I;  3FP7 J;  4NTY B;  3AUI A;  1AAL A;  1EJM B;  1T8M B;  3FP8 I;  5JB7 A;  3BTD I;  1FAK I;  1YKT B;  4BNR I;  1YLD B;  3BTQ I;  1TOC R;  2KNT A;  4Y10 I;  1BRB I;  1T8O B;  1JV9 A;  3CI7 A;  3LDJ A;  1BZ5 A;  2KAI I;  4Y11 I;  1T8L B;  1JC6 A;  1T8N B;  2DDJ A;  3AUE A;  1P2Q B;  3BTM I;  4Y0Y I; 
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