1PBWA

Structure of bcr-homology (bh) domain
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
184
structure length
184
Chain Sequence
LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Phosphotransferase
molecule keywords PHOSPHATIDYLINOSITOL 3-KINASE
publication title Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
pubmed doi rcsb
source organism Homo sapiens
total genus 67
structure length 184
sequence length 184
chains with identical sequence B
ec nomenclature
pdb deposition date 1996-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 1pbwA00
1OW3A 5IRCA 5C5SA 3BYIA 3KUQA 3IUGA 1AM4A 2QV2A 3CXLA 3WPQA 5JD0A 2OSAA 2EE4A 1RGPA 3WPSA 2OVJA 2EE5A 1GRNB 3MSXB 2XS6A 2NGRB 3EAPA 3FK2A 1PBWA 5C2JA 1XA6A 2MBGA 3W6RA 3QISA 1TX4A 5HPYA 5JCPA 1F7CA
chains in the Genus database with same CATH superfamily
1OW3A 5IRCA 5C5SA 3BYIA 3KUQA 3IUGA 1AM4A 2QV2A 3CXLA 3WPQA 5JD0A 2OSAA 2EE4A 1RGPA 3WPSA 2OVJA 2EE5A 1GRNB 3MSXB 2XS6A 2NGRB 3EAPA 3FK2A 1PBWA 5C2JA 1XA6A 2MBGA 3W6RA 3QISA 1TX4A 5HPYA 5JCPA 1F7CA
chains in the Genus database with same CATH topology
1OW3A 5IRCA 5C5SA 3BYIA 3KUQA 3IUGA 1AM4A 2QV2A 3CXLA 3WPQA 5JD0A 2OSAA 2EE4A 1RGPA 3WPSA 2OVJA 2EE5A 1GRNB 3MSXB 2XS6A 2NGRB 3EAPA 3FK2A 1PBWA 5C2JA 1XA6A 2MBGA 3W6RA 3QISA 1TX4A 5HPYA 5JCPA 1F7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OW3 A;  5IRC A;  5C5S A;  3BYI A;  3KUQ A;  3IUG A;  1AM4 A;  2QV2 A;  3CXL A;  3WPQ A;  5JD0 A;  2OSA A;  2EE4 A;  1RGP A;  3WPS A;  2OVJ A;  2EE5 A;  1GRN B;  3MSX B;  2XS6 A;  2NGR B;  3EAP A;  3FK2 A;  1PBW A;  5C2J A;  1XA6 A;  2MBG A;  3W6R A;  3QIS A;  1TX4 A;  5HPY A;  5JCP A;  1F7C A; 
#chains in the Genus database with same CATH topology
 1OW3 A;  5IRC A;  5C5S A;  3BYI A;  3KUQ A;  3IUG A;  1AM4 A;  2QV2 A;  3CXL A;  3WPQ A;  5JD0 A;  2OSA A;  2EE4 A;  1RGP A;  3WPS A;  2OVJ A;  2EE5 A;  1GRN B;  3MSX B;  2XS6 A;  2NGR B;  3EAP A;  3FK2 A;  1PBW A;  5C2J A;  1XA6 A;  2MBG A;  3W6R A;  3QIS A;  1TX4 A;  5HPY A;  5JCP A;  1F7C A; 
#chains in the Genus database with same CATH homology
 1OW3 A;  5IRC A;  5C5S A;  3BYI A;  3KUQ A;  3IUG A;  1AM4 A;  2QV2 A;  3CXL A;  3WPQ A;  5JD0 A;  2OSA A;  2EE4 A;  1RGP A;  3WPS A;  2OVJ A;  2EE5 A;  1GRN B;  3MSX B;  2XS6 A;  2NGR B;  3EAP A;  3FK2 A;  1PBW A;  5C2J A;  1XA6 A;  2MBG A;  3W6R A;  3QIS A;  1TX4 A;  5HPY A;  5JCP A;  1F7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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