1PEXA

Collagenase-3 (mmp-13) c-terminal hemopexin-like domain
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
192
structure length
192
Chain Sequence
TPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Metalloprotease
molecule keywords COLLAGENASE-3
publication title The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 32
structure length 192
sequence length 192
ec nomenclature ec 3.4.24.-:
pdb deposition date 1996-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 1pexA00
1ITVA 4OEIA 1HXNA 4RT6B 2JXYA 4FU4A 3C7XA 4LL2A 1QJSA 1PEXA 2CLTA 3LP9A 1GENA 1FBLA 3OYOA 4YEHA 1GXDA 4AUOA 1CK7A 1QHUA 1RTGA 1SU3A 4HSDA 3V6NA 3BA0A 2MQSA 3S18A 4FVLA 4G0DA
chains in the Genus database with same CATH superfamily
1ITVA 4OEIA 1HXNA 4RT6B 2JXYA 4FU4A 3C7XA 4LL2A 1QJSA 1PEXA 2CLTA 3LP9A 1GENA 1FBLA 3OYOA 4YEHA 1GXDA 4AUOA 1CK7A 1QHUA 1RTGA 1SU3A 4HSDA 3V6NA 3BA0A 2MQSA 3S18A 4FVLA 4G0DA
chains in the Genus database with same CATH topology
1ITVA 4OEIA 1HXNA 4RT6B 2JXYA 4FU4A 3C7XA 4LL2A 1QJSA 1PEXA 2CLTA 3LP9A 1GENA 1FBLA 3OYOA 4YEHA 1GXDA 4AUOA 1CK7A 1QHUA 1RTGA 1SU3A 4HSDA 3V6NA 3BA0A 2MQSA 3S18A 4FVLA 4G0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ITV A;  4OEI A;  1HXN A;  4RT6 B;  2JXY A;  4FU4 A;  3C7X A;  4LL2 A;  1QJS A;  1PEX A;  2CLT A;  3LP9 A;  1GEN A;  1FBL A;  3OYO A;  4YEH A;  1GXD A;  4AUO A;  1CK7 A;  1QHU A;  1RTG A;  1SU3 A;  4HSD A;  3V6N A;  3BA0 A;  2MQS A;  3S18 A;  4FVL A;  4G0D A; 
#chains in the Genus database with same CATH topology
 1ITV A;  4OEI A;  1HXN A;  4RT6 B;  2JXY A;  4FU4 A;  3C7X A;  4LL2 A;  1QJS A;  1PEX A;  2CLT A;  3LP9 A;  1GEN A;  1FBL A;  3OYO A;  4YEH A;  1GXD A;  4AUO A;  1CK7 A;  1QHU A;  1RTG A;  1SU3 A;  4HSD A;  3V6N A;  3BA0 A;  2MQS A;  3S18 A;  4FVL A;  4G0D A; 
#chains in the Genus database with same CATH homology
 1ITV A;  4OEI A;  1HXN A;  4RT6 B;  2JXY A;  4FU4 A;  3C7X A;  4LL2 A;  1QJS A;  1PEX A;  2CLT A;  3LP9 A;  1GEN A;  1FBL A;  3OYO A;  4YEH A;  1GXD A;  4AUO A;  1CK7 A;  1QHU A;  1RTG A;  1SU3 A;  4HSD A;  3V6N A;  3BA0 A;  2MQS A;  3S18 A;  4FVL A;  4G0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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