1QLQA

Bovine pancreatic trypsin inhibitor (bpti) mutant with altered binding loop sequence
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYAGACRARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence
pubmed doi rcsb
molecule tags Serine protease inhibitor
source organism Bos taurus
molecule keywords PANCREATIC TRYPSIN INHIBITOR
total genus 8
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 1999-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1qlqA00
4ISNB 1DENA 1PITA 3GYMI 3T62D 1BF0A 1BZXI 4Y10I 1BRBI 1AALA 2RA3C 3LDIA 3TPII 4DG4C 1UUAA 3BTEI 1K6UA 3FP6I 1YKTB 3TGJI 4ISLB 4WWYC 3BTTI 1TAWB 1BTHP 1TAPA 1P2JI 1BTIA 3AUGA 4NTYB 2KNTA 3WNYA 1T7CB 3U1JE 4DTGK 1CO7I 2UUXA 1KNTA 3BTWI 2KCRA 1OA65 2FTMB 3UIRC 4BQDA 2R9PE 1BHCA 3AUCA 2M01A 1F5RI 3TGII 1MTND 1D0DB 3OFWA 2FI4I 1T8NB 1BRCI 1G6XA 1DTXA 3AUIA 1P2II 1P2MB 3P92E 3AUHA 3BTDI 1IRHA 2LFKA 1T8OB 5JB6A 5JB4A 3M7QB 4NTXB 1P2OB 4ISOB 4BD9B 1EAWB 3BYBA 4NTWB 3CI7A 1JC6A 1F7ZI 1OA55 2FI5I 2ZJXA 8PTIA 4Y11I 1AAPA 1BPIA 1T8MB 1JV8A 1KTHA 4Y0YI 1LD6A 3FP8I 3BTMI 1FAKI 1SHPA 2FTLI 1CBWD 1B0CA 2CA7A 4Y0ZI 2J6DA 1DTKA 3UOUB 2W8XA 1QLQA 1P2QB 2FI3I 3LDJA 1P2KI 6PTIA 5JB7A 3AUDA 2HEXA 3OTJI 1CA0D 1KIGI 4PTIA 4BNRI 1FY8I 1YC0I 2DDJA 2IJOI 2PTCI 2TPII 3BTGI 3BTQI 4U30W 3BTKI 3BTHI 2TGPI 1BZ5A 5JB5A 1T8LB 1ZJDB 1ADZA 2ODYE 3L3TE 1BPTA 2KAII 1ZR0B 5PTIA 1YLCB 1NAGA 3FP7J 1UUBA 3BTFI 4WXVC 2UUYB 4TPII 3D65I 2DDIA 3AUEA 1BUNB 1YLDB 1D0DA 1Y62A 3LDMA 3P95E 1TOCR 5C67C 7PTIA 9PTIA 1KUNA 1BIKA 3AUBA 1TPAI 1EJMB 3TGKI 1TFXC 1JV9A 1P2NB 2ZVXA 1FANA 2JOTA 4U32X 3L33E 1DEMA 2LFLA 1LD5A 1TCPA 2M99A
chains in the Genus database with same CATH superfamily
4ISNB 1DENA 1PITA 3GYMI 3T62D 1BF0A 1BZXI 4Y10I 1BRBI 1AALA 2RA3C 3LDIA 3TPII 4DG4C 1UUAA 3BTEI 1K6UA 3FP6I 1YKTB 3TGJI 4ISLB 4WWYC 3BTTI 1TAWB 1BTHP 1TAPA 1P2JI 1BTIA 3AUGA 4NTYB 2KNTA 3WNYA 1T7CB 3U1JE 4DTGK 1CO7I 2UUXA 1KNTA 3BTWI 2KCRA 1OA65 2FTMB 3UIRC 4BQDA 2R9PE 1BHCA 3AUCA 2M01A 1F5RI 3TGII 1MTND 1D0DB 3OFWA 2FI4I 1T8NB 1BRCI 1G6XA 1DTXA 3AUIA 1P2II 1P2MB 3P92E 3AUHA 3BTDI 1IRHA 2LFKA 1T8OB 5JB6A 5JB4A 3M7QB 4NTXB 1P2OB 4ISOB 4BD9B 1EAWB 3BYBA 4NTWB 3CI7A 1JC6A 1F7ZI 1OA55 2FI5I 2ZJXA 8PTIA 4Y11I 1AAPA 1BPIA 1T8MB 1JV8A 1KTHA 4Y0YI 1LD6A 3FP8I 3BTMI 1FAKI 1SHPA 2FTLI 1CBWD 1B0CA 2CA7A 4Y0ZI 2J6DA 1DTKA 3UOUB 2W8XA 1QLQA 1P2QB 2FI3I 3LDJA 1P2KI 6PTIA 5JB7A 3AUDA 2HEXA 3OTJI 1CA0D 1KIGI 4PTIA 4BNRI 1FY8I 1YC0I 2DDJA 2IJOI 2PTCI 2TPII 3BTGI 3BTQI 4U30W 3BTKI 3BTHI 2TGPI 1BZ5A 5JB5A 1T8LB 1ZJDB 1ADZA 2ODYE 3L3TE 1BPTA 2KAII 1ZR0B 5PTIA 1YLCB 1NAGA 3FP7J 1UUBA 3BTFI 4WXVC 2UUYB 4TPII 3D65I 2DDIA 3AUEA 1BUNB 1YLDB 1D0DA 1Y62A 3LDMA 3P95E 1TOCR 5C67C 7PTIA 9PTIA 1KUNA 1BIKA 3AUBA 1TPAI 1EJMB 3TGKI 1TFXC 1JV9A 1P2NB 2ZVXA 1FANA 2JOTA 4U32X 3L33E 1DEMA 2LFLA 1LD5A 1TCPA 2M99A
chains in the Genus database with same CATH topology
4ISNB 1DENA 1PITA 3GYMI 3T62D 1BF0A 1BZXI 4Y10I 1BRBI 1AALA 2RA3C 3LDIA 3TPII 4DG4C 1UUAA 3BTEI 1K6UA 3FP6I 1YKTB 3TGJI 4ISLB 4WWYC 3BTTI 1TAWB 1BTHP 1TAPA 1P2JI 1BTIA 3AUGA 4NTYB 2KNTA 3WNYA 1T7CB 3U1JE 4DTGK 1CO7I 2UUXA 1KNTA 3BTWI 2KCRA 1OA65 2FTMB 3UIRC 4BQDA 2R9PE 1BHCA 3AUCA 2M01A 1F5RI 3TGII 1MTND 1D0DB 3OFWA 2FI4I 1T8NB 1BRCI 1G6XA 1DTXA 3AUIA 1P2II 1P2MB 3P92E 3AUHA 3BTDI 1IRHA 2LFKA 1T8OB 5JB6A 5JB4A 3M7QB 4NTXB 1P2OB 4ISOB 4BD9B 1EAWB 3BYBA 4NTWB 3CI7A 1JC6A 1F7ZI 1OA55 2FI5I 2ZJXA 8PTIA 4Y11I 1AAPA 1BPIA 1T8MB 1JV8A 1KTHA 4Y0YI 1LD6A 3FP8I 3BTMI 1FAKI 1SHPA 2FTLI 1CBWD 1B0CA 2CA7A 4Y0ZI 2J6DA 1DTKA 3UOUB 2W8XA 1QLQA 1P2QB 2FI3I 3LDJA 1P2KI 6PTIA 5JB7A 3AUDA 2HEXA 3OTJI 1CA0D 1KIGI 4PTIA 4BNRI 1FY8I 1YC0I 2DDJA 2IJOI 2PTCI 2TPII 3BTGI 3BTQI 4U30W 3BTKI 3BTHI 2TGPI 1BZ5A 5JB5A 1T8LB 1ZJDB 1ADZA 2ODYE 3L3TE 1BPTA 2KAII 1ZR0B 5PTIA 1YLCB 1NAGA 3FP7J 1UUBA 3BTFI 4WXVC 2UUYB 4TPII 3D65I 2DDIA 3AUEA 1BUNB 1YLDB 1D0DA 1Y62A 3LDMA 3P95E 1TOCR 5C67C 7PTIA 9PTIA 1KUNA 1BIKA 3AUBA 1TPAI 1EJMB 3TGKI 1TFXC 1JV9A 1P2NB 2ZVXA 1FANA 2JOTA 4U32X 3L33E 1DEMA 2LFLA 1LD5A 1TCPA 2M99A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ISN B;  1DEN A;  1PIT A;  3GYM I;  3T62 D;  1BF0 A;  1BZX I;  4Y10 I;  1BRB I;  1AAL A;  2RA3 C;  3LDI A;  3TPI I;  4DG4 C;  1UUA A;  3BTE I;  1K6U A;  3FP6 I;  1YKT B;  3TGJ I;  4ISL B;  4WWY C;  3BTT I;  1TAW B;  1BTH P;  1TAP A;  1P2J I;  1BTI A;  3AUG A;  4NTY B;  2KNT A;  3WNY A;  1T7C B;  3U1J E;  4DTG K;  1CO7 I;  2UUX A;  1KNT A;  3BTW I;  2KCR A;  1OA6 5;  2FTM B;  3UIR C;  4BQD A;  2R9P E;  1BHC A;  3AUC A;  2M01 A;  1F5R I;  3TGI I;  1MTN D;  1D0D B;  3OFW A;  2FI4 I;  1T8N B;  1BRC I;  1G6X A;  1DTX A;  3AUI A;  1P2I I;  1P2M B;  3P92 E;  3AUH A;  3BTD I;  1IRH A;  2LFK A;  1T8O B;  5JB6 A;  5JB4 A;  3M7Q B;  4NTX B;  1P2O B;  4ISO B;  4BD9 B;  1EAW B;  3BYB A;  4NTW B;  3CI7 A;  1JC6 A;  1F7Z I;  1OA5 5;  2FI5 I;  2ZJX A;  8PTI A;  4Y11 I;  1AAP A;  1BPI A;  1T8M B;  1JV8 A;  1KTH A;  4Y0Y I;  1LD6 A;  3FP8 I;  3BTM I;  1FAK I;  1SHP A;  2FTL I;  1CBW D;  1B0C A;  2CA7 A;  4Y0Z I;  2J6D A;  1DTK A;  3UOU B;  2W8X A;  1QLQ A;  1P2Q B;  2FI3 I;  3LDJ A;  1P2K I;  6PTI A;  5JB7 A;  3AUD A;  2HEX A;  3OTJ I;  1CA0 D;  1KIG I;  4PTI A;  4BNR I;  1FY8 I;  1YC0 I;  2DDJ A;  2IJO I;  2PTC I;  2TPI I;  3BTG I;  3BTQ I;  4U30 W;  3BTK I;  3BTH I;  2TGP I;  1BZ5 A;  5JB5 A;  1T8L B;  1ZJD B;  1ADZ A;  2ODY E;  3L3T E;  1BPT A;  2KAI I;  1ZR0 B;  5PTI A;  1YLC B;  1NAG A;  3FP7 J;  1UUB A;  3BTF I;  4WXV C;  2UUY B;  4TPI I;  3D65 I;  2DDI A;  3AUE A;  1BUN B;  1YLD B;  1D0D A;  1Y62 A;  3LDM A;  3P95 E;  1TOC R;  5C67 C;  7PTI A;  9PTI A;  1KUN A;  1BIK A;  3AUB A;  1TPA I;  1EJM B;  3TGK I;  1TFX C;  1JV9 A;  1P2N B;  2ZVX A;  1FAN A;  2JOT A;  4U32 X;  3L33 E;  1DEM A;  2LFL A;  1LD5 A;  1TCP A;  2M99 A; 
#chains in the Genus database with same CATH topology
 4ISN B;  1DEN A;  1PIT A;  3GYM I;  3T62 D;  1BF0 A;  1BZX I;  4Y10 I;  1BRB I;  1AAL A;  2RA3 C;  3LDI A;  3TPI I;  4DG4 C;  1UUA A;  3BTE I;  1K6U A;  3FP6 I;  1YKT B;  3TGJ I;  4ISL B;  4WWY C;  3BTT I;  1TAW B;  1BTH P;  1TAP A;  1P2J I;  1BTI A;  3AUG A;  4NTY B;  2KNT A;  3WNY A;  1T7C B;  3U1J E;  4DTG K;  1CO7 I;  2UUX A;  1KNT A;  3BTW I;  2KCR A;  1OA6 5;  2FTM B;  3UIR C;  4BQD A;  2R9P E;  1BHC A;  3AUC A;  2M01 A;  1F5R I;  3TGI I;  1MTN D;  1D0D B;  3OFW A;  2FI4 I;  1T8N B;  1BRC I;  1G6X A;  1DTX A;  3AUI A;  1P2I I;  1P2M B;  3P92 E;  3AUH A;  3BTD I;  1IRH A;  2LFK A;  1T8O B;  5JB6 A;  5JB4 A;  3M7Q B;  4NTX B;  1P2O B;  4ISO B;  4BD9 B;  1EAW B;  3BYB A;  4NTW B;  3CI7 A;  1JC6 A;  1F7Z I;  1OA5 5;  2FI5 I;  2ZJX A;  8PTI A;  4Y11 I;  1AAP A;  1BPI A;  1T8M B;  1JV8 A;  1KTH A;  4Y0Y I;  1LD6 A;  3FP8 I;  3BTM I;  1FAK I;  1SHP A;  2FTL I;  1CBW D;  1B0C A;  2CA7 A;  4Y0Z I;  2J6D A;  1DTK A;  3UOU B;  2W8X A;  1QLQ A;  1P2Q B;  2FI3 I;  3LDJ A;  1P2K I;  6PTI A;  5JB7 A;  3AUD A;  2HEX A;  3OTJ I;  1CA0 D;  1KIG I;  4PTI A;  4BNR I;  1FY8 I;  1YC0 I;  2DDJ A;  2IJO I;  2PTC I;  2TPI I;  3BTG I;  3BTQ I;  4U30 W;  3BTK I;  3BTH I;  2TGP I;  1BZ5 A;  5JB5 A;  1T8L B;  1ZJD B;  1ADZ A;  2ODY E;  3L3T E;  1BPT A;  2KAI I;  1ZR0 B;  5PTI A;  1YLC B;  1NAG A;  3FP7 J;  1UUB A;  3BTF I;  4WXV C;  2UUY B;  4TPI I;  3D65 I;  2DDI A;  3AUE A;  1BUN B;  1YLD B;  1D0D A;  1Y62 A;  3LDM A;  3P95 E;  1TOC R;  5C67 C;  7PTI A;  9PTI A;  1KUN A;  1BIK A;  3AUB A;  1TPA I;  1EJM B;  3TGK I;  1TFX C;  1JV9 A;  1P2N B;  2ZVX A;  1FAN A;  2JOT A;  4U32 X;  3L33 E;  1DEM A;  2LFL A;  1LD5 A;  1TCP A;  2M99 A; 
#chains in the Genus database with same CATH homology
 4ISN B;  1DEN A;  1PIT A;  3GYM I;  3T62 D;  1BF0 A;  1BZX I;  4Y10 I;  1BRB I;  1AAL A;  2RA3 C;  3LDI A;  3TPI I;  4DG4 C;  1UUA A;  3BTE I;  1K6U A;  3FP6 I;  1YKT B;  3TGJ I;  4ISL B;  4WWY C;  3BTT I;  1TAW B;  1BTH P;  1TAP A;  1P2J I;  1BTI A;  3AUG A;  4NTY B;  2KNT A;  3WNY A;  1T7C B;  3U1J E;  4DTG K;  1CO7 I;  2UUX A;  1KNT A;  3BTW I;  2KCR A;  1OA6 5;  2FTM B;  3UIR C;  4BQD A;  2R9P E;  1BHC A;  3AUC A;  2M01 A;  1F5R I;  3TGI I;  1MTN D;  1D0D B;  3OFW A;  2FI4 I;  1T8N B;  1BRC I;  1G6X A;  1DTX A;  3AUI A;  1P2I I;  1P2M B;  3P92 E;  3AUH A;  3BTD I;  1IRH A;  2LFK A;  1T8O B;  5JB6 A;  5JB4 A;  3M7Q B;  4NTX B;  1P2O B;  4ISO B;  4BD9 B;  1EAW B;  3BYB A;  4NTW B;  3CI7 A;  1JC6 A;  1F7Z I;  1OA5 5;  2FI5 I;  2ZJX A;  8PTI A;  4Y11 I;  1AAP A;  1BPI A;  1T8M B;  1JV8 A;  1KTH A;  4Y0Y I;  1LD6 A;  3FP8 I;  3BTM I;  1FAK I;  1SHP A;  2FTL I;  1CBW D;  1B0C A;  2CA7 A;  4Y0Z I;  2J6D A;  1DTK A;  3UOU B;  2W8X A;  1QLQ A;  1P2Q B;  2FI3 I;  3LDJ A;  1P2K I;  6PTI A;  5JB7 A;  3AUD A;  2HEX A;  3OTJ I;  1CA0 D;  1KIG I;  4PTI A;  4BNR I;  1FY8 I;  1YC0 I;  2DDJ A;  2IJO I;  2PTC I;  2TPI I;  3BTG I;  3BTQ I;  4U30 W;  3BTK I;  3BTH I;  2TGP I;  1BZ5 A;  5JB5 A;  1T8L B;  1ZJD B;  1ADZ A;  2ODY E;  3L3T E;  1BPT A;  2KAI I;  1ZR0 B;  5PTI A;  1YLC B;  1NAG A;  3FP7 J;  1UUB A;  3BTF I;  4WXV C;  2UUY B;  4TPI I;  3D65 I;  2DDI A;  3AUE A;  1BUN B;  1YLD B;  1D0D A;  1Y62 A;  3LDM A;  3P95 E;  1TOC R;  5C67 C;  7PTI A;  9PTI A;  1KUN A;  1BIK A;  3AUB A;  1TPA I;  1EJM B;  3TGK I;  1TFX C;  1JV9 A;  1P2N B;  2ZVX A;  1FAN A;  2JOT A;  4U32 X;  3L33 E;  1DEM A;  2LFL A;  1LD5 A;  1TCP A;  2M99 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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