1RE3B

Crystal structure of fragment d of bbetad398a fibrinogen with the peptide ligand gly-his-arg-pro-amide
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
294
structure length
294
Chain Sequence
LRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEAGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Fibrinogen alpha/alpha-E chain
total genus 87
structure length 294
sequence length 294
chains with identical sequence E
ec nomenclature
pdb deposition date 2003-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1re3B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1re3B02
1RE4B 1Z3SA 2FFDB 1FZFC 2J0GA 2HPCB 2HLOC 2Q9IB 1LTJC 4M7HA 1Z3UA 2JHKF 2J0HA 1RE3B 1M1JB 2J3FD 1FZEB 2GY7A 2OYIB 1RF0C 1N86B 2J0YA 3GHGC 2J61B 2J3UA 1RF1B 2J60A 4M7FA 4ZFGA 1N73B 4R9TA 3BVHC 2OYHC 2J3OA 1FZFB 3E1IB 2H43C 2HLOB 1LTJB 3H32B 1LWUC 1FZBC 2J3FA 1FIDA 1FZCC 1RE4C 4R9JA 1FZAC 1FICA 4JZCA 2FFDC 2FIBA 2XNXB 2JHHC 1LT9C 2Q9IC 1FZGC 3HUSB 2HODC 2JHLF 4NYTA 2Z4EB 1M1JC 2JHIF 1FZEC 1FIBA 4EPUA 2J2PA 1FZDA 2J3GA 2D39A 1RF1C 2J61A 1N73C 2WNPF 1FZCB 2HPCC 1JC9A 1RF0B 3FIBA 1FZAB 2J5ZA 4JYOX 3E1IC 1RE3C 1LT9B 1FZGB 3H32C 2J64A 2HODB 2OYIC 2J1GA 1N86C 3BVHB 2OYHB 2XNXC 2JHMF 3HUSC 2H43B 1LWUB 2Z4EC 1FZBB
chains in the Genus database with same CATH superfamily
1RE4B 1Z3SA 2FFDB 1FZFC 2J0GA 2HPCB 2HLOC 2Q9IB 1LTJC 4M7HA 1Z3UA 2JHKF 2J0HA 1RE3B 1M1JB 2J3FD 1FZEB 2GY7A 2OYIB 1RF0C 1N86B 2J0YA 3GHGC 2J61B 2J3UA 1RF1B 2J60A 4M7FA 4ZFGA 1N73B 4R9TA 3BVHC 2OYHC 2J3OA 1FZFB 3E1IB 2H43C 2HLOB 1LTJB 3H32B 1LWUC 1FZBC 2J3FA 1FIDA 1FZCC 1RE4C 4R9JA 1FZAC 1FICA 4JZCA 2FFDC 2FIBA 2XNXB 2JHHC 1LT9C 2Q9IC 1FZGC 3HUSB 2HODC 2JHLF 3GHGB 4NYTA 2Z4EB 1M1JC 2JHIF 1FZEC 1FIBA 4EPUA 2J2PA 1FZDA 2J3GA 2D39A 1RF1C 2J61A 1N73C 2WNPF 1FZCB 2HPCC 1JC9A 1RF0B 3FIBA 1FZAB 2J5ZA 4JYOX 3E1IC 1RE3C 1LT9B 1FZGB 3H32C 2J64A 2HODB 2OYIC 2J1GA 1N86C 3BVHB 2OYHB 2XNXC 2JHMF 3HUSC 2H43B 1LWUB 2Z4EC 1FZBB
chains in the Genus database with same CATH topology
1RE4B 1Z3SA 2FFDB 1FZFC 2J0GA 2HPCB 2HLOC 2Q9IB 1LTJC 4M7HA 1Z3UA 2JHKF 2J0HA 1RE3B 1M1JB 2J3FD 1FZEB 2GY7A 2OYIB 1RF0C 1N86B 2J0YA 3GHGC 2J61B 2J3UA 1RF1B 2J60A 4M7FA 4ZFGA 1N73B 4R9TA 3BVHC 2OYHC 2J3OA 1FZFB 3E1IB 2H43C 2HLOB 1LTJB 3H32B 1LWUC 1FZBC 2J3FA 1FIDA 1FZCC 1RE4C 4R9JA 1FZAC 1FICA 4JZCA 2FFDC 2FIBA 2XNXB 2JHHC 1LT9C 2Q9IC 1FZGC 3HUSB 2HODC 2JHLF 4NYTA 2Z4EB 1M1JC 2JHIF 1FZEC 1FIBA 4EPUA 2J2PA 1FZDA 2J3GA 2D39A 1RF1C 2J61A 1N73C 2WNPF 1FZCB 2HPCC 1JC9A 1RF0B 3FIBA 1FZAB 2J5ZA 4JYOX 3E1IC 1RE3C 1LT9B 1FZGB 3H32C 2J64A 2HODB 2OYIC 2J1GA 1N86C 3BVHB 2OYHB 2XNXC 2JHMF 3HUSC 2H43B 1LWUB 2Z4EC 1FZBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RE4 B;  1Z3S A;  2FFD B;  1FZF C;  2J0G A;  2HPC B;  2HLO C;  2Q9I B;  1LTJ C;  4M7H A;  1Z3U A;  2JHK F;  2J0H A;  1RE3 B;  1M1J B;  2J3F D;  1FZE B;  2GY7 A;  2OYI B;  1RF0 C;  1N86 B;  2J0Y A;  3GHG C;  2J61 B;  2J3U A;  1RF1 B;  2J60 A;  4M7F A;  4ZFG A;  1N73 B;  4R9T A;  3BVH C;  2OYH C;  2J3O A;  1FZF B;  3E1I B;  2H43 C;  2HLO B;  1LTJ B;  3H32 B;  1LWU C;  1FZB C;  2J3F A;  1FID A;  1FZC C;  1RE4 C;  4R9J A;  1FZA C;  1FIC A;  4JZC A;  2FFD C;  2FIB A;  2XNX B;  2JHH C;  1LT9 C;  2Q9I C;  1FZG C;  3HUS B;  2HOD C;  2JHL F;  4NYT A;  2Z4E B;  1M1J C;  2JHI F;  1FZE C;  1FIB A;  4EPU A;  2J2P A;  1FZD A;  2J3G A;  2D39 A;  1RF1 C;  2J61 A;  1N73 C;  2WNP F;  1FZC B;  2HPC C;  1JC9 A;  1RF0 B;  3FIB A;  1FZA B;  2J5Z A;  4JYO X;  3E1I C;  1RE3 C;  1LT9 B;  1FZG B;  3H32 C;  2J64 A;  2HOD B;  2OYI C;  2J1G A;  1N86 C;  3BVH B;  2OYH B;  2XNX C;  2JHM F;  3HUS C;  2H43 B;  1LWU B;  2Z4E C;  1FZB B; 
#chains in the Genus database with same CATH topology
 1RE4 B;  1Z3S A;  2FFD B;  1FZF C;  2J0G A;  2HPC B;  2HLO C;  2Q9I B;  1LTJ C;  4M7H A;  1Z3U A;  2JHK F;  2J0H A;  1RE3 B;  1M1J B;  2J3F D;  1FZE B;  2GY7 A;  2OYI B;  1RF0 C;  1N86 B;  2J0Y A;  3GHG C;  2J61 B;  2J3U A;  1RF1 B;  2J60 A;  4M7F A;  4ZFG A;  1N73 B;  4R9T A;  3BVH C;  2OYH C;  2J3O A;  1FZF B;  3E1I B;  2H43 C;  2HLO B;  1LTJ B;  3H32 B;  1LWU C;  1FZB C;  2J3F A;  1FID A;  1FZC C;  1RE4 C;  4R9J A;  1FZA C;  1FIC A;  4JZC A;  2FFD C;  2FIB A;  2XNX B;  2JHH C;  1LT9 C;  2Q9I C;  1FZG C;  3HUS B;  2HOD C;  2JHL F;  3GHG B;  4NYT A;  2Z4E B;  1M1J C;  2JHI F;  1FZE C;  1FIB A;  4EPU A;  2J2P A;  1FZD A;  2J3G A;  2D39 A;  1RF1 C;  2J61 A;  1N73 C;  2WNP F;  1FZC B;  2HPC C;  1JC9 A;  1RF0 B;  3FIB A;  1FZA B;  2J5Z A;  4JYO X;  3E1I C;  1RE3 C;  1LT9 B;  1FZG B;  3H32 C;  2J64 A;  2HOD B;  2OYI C;  2J1G A;  1N86 C;  3BVH B;  2OYH B;  2XNX C;  2JHM F;  3HUS C;  2H43 B;  1LWU B;  2Z4E C;  1FZB B; 
#chains in the Genus database with same CATH homology
 1RE4 B;  1Z3S A;  2FFD B;  1FZF C;  2J0G A;  2HPC B;  2HLO C;  2Q9I B;  1LTJ C;  4M7H A;  1Z3U A;  2JHK F;  2J0H A;  1RE3 B;  1M1J B;  2J3F D;  1FZE B;  2GY7 A;  2OYI B;  1RF0 C;  1N86 B;  2J0Y A;  3GHG C;  2J61 B;  2J3U A;  1RF1 B;  2J60 A;  4M7F A;  4ZFG A;  1N73 B;  4R9T A;  3BVH C;  2OYH C;  2J3O A;  1FZF B;  3E1I B;  2H43 C;  2HLO B;  1LTJ B;  3H32 B;  1LWU C;  1FZB C;  2J3F A;  1FID A;  1FZC C;  1RE4 C;  4R9J A;  1FZA C;  1FIC A;  4JZC A;  2FFD C;  2FIB A;  2XNX B;  2JHH C;  1LT9 C;  2Q9I C;  1FZG C;  3HUS B;  2HOD C;  2JHL F;  4NYT A;  2Z4E B;  1M1J C;  2JHI F;  1FZE C;  1FIB A;  4EPU A;  2J2P A;  1FZD A;  2J3G A;  2D39 A;  1RF1 C;  2J61 A;  1N73 C;  2WNP F;  1FZC B;  2HPC C;  1JC9 A;  1RF0 B;  3FIB A;  1FZA B;  2J5Z A;  4JYO X;  3E1I C;  1RE3 C;  1LT9 B;  1FZG B;  3H32 C;  2J64 A;  2HOD B;  2OYI C;  2J1G A;  1N86 C;  3BVH B;  2OYH B;  2XNX C;  2JHM F;  3HUS C;  2H43 B;  1LWU B;  2Z4E C;  1FZB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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