1RE4B

Crystal structure of fragment d of bbetad398a fibrinogen
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
306
structure length
306
Chain Sequence
DETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEAGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Fibrinogen alpha/alpha-E chain
total genus 89
structure length 306
sequence length 306
chains with identical sequence E
ec nomenclature
pdb deposition date 2003-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1re4B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1re4B02
2J61B 1LWUC 1FZCB 1M1JB 1FZAC 2XNXC 1N86C 2J61A 2J0YA 2J0GA 2OYIB 1FIDA 2J2PA 3H32B 1FZFC 1FICA 1RE4C 1LT9C 2Q9IC 2JHLF 1LWUB 4JYOX 2XNXB 2J3UA 2JHKF 2J3GA 2OYHC 4M7HA 2HODC 3HUSC 1FZBC 3E1IC 2J3FD 1FZFB 2GY7A 2HLOC 4M7FA 1N73B 2J3OA 1LT9B 2Q9IB 2H43C 1RE3B 1RF0C 2J0HA 2HPCC 3BVHC 1FZEC 2J1GA 2FFDC 1FZAB 1N86B 2HODB 1M1JC 2JHMF 1JC9A 3HUSB 4R9JA 1Z3SA 1FZGC 2OYIC 1FIBA 2JHHC 2FIBA 2WNPF 2HLOB 2H43B 1RF0B 1RE4B 2HPCB 1RF1C 2J3FA 3BVHB 1FZEB 2Z4EC 2FFDB 4NYTA 2J60A 1LTJC 2OYHB 1FZCC 3GHGC 3FIBA 1FZDA 1FZGB 1Z3UA 1FZBB 2J64A 3E1IB 4EPUA 2JHIF 4ZFGA 1RF1B 3H32C 2D39A 4JZCA 1N73C 1RE3C 2Z4EB 2J5ZA 4R9TA 1LTJB
chains in the Genus database with same CATH superfamily
2J61B 1LWUC 1FZCB 1M1JB 1FZAC 2XNXC 1N86C 3GHGB 2J61A 2J0YA 2J0GA 2OYIB 1FIDA 2J2PA 3H32B 1FZFC 1FICA 1RE4C 1LT9C 2Q9IC 2JHLF 1LWUB 4JYOX 2XNXB 2J3UA 2JHKF 2J3GA 2OYHC 4M7HA 2HODC 3HUSC 1FZBC 3E1IC 2J3FD 1FZFB 2GY7A 2HLOC 4M7FA 1N73B 2J3OA 1LT9B 2Q9IB 2H43C 1RE3B 1RF0C 2J0HA 2HPCC 3BVHC 1FZEC 2J1GA 2FFDC 1FZAB 1N86B 2HODB 1M1JC 2JHMF 1JC9A 3HUSB 4R9JA 1Z3SA 1FZGC 2OYIC 1FIBA 2JHHC 2FIBA 2WNPF 2HLOB 2H43B 1RF0B 1RE4B 2HPCB 1RF1C 2J3FA 3BVHB 1FZEB 2Z4EC 2FFDB 4NYTA 2J60A 1LTJC 2OYHB 1FZCC 3GHGC 3FIBA 1FZDA 1FZGB 1Z3UA 1FZBB 2J64A 3E1IB 4EPUA 2JHIF 4ZFGA 1RF1B 3H32C 2D39A 4JZCA 1N73C 1RE3C 2Z4EB 2J5ZA 4R9TA 1LTJB
chains in the Genus database with same CATH topology
2J61B 1LWUC 1FZCB 1M1JB 1FZAC 2XNXC 1N86C 2J61A 2J0YA 2J0GA 2OYIB 1FIDA 2J2PA 3H32B 1FZFC 1FICA 1RE4C 1LT9C 2Q9IC 2JHLF 1LWUB 4JYOX 2XNXB 2J3UA 2JHKF 2J3GA 2OYHC 4M7HA 2HODC 3HUSC 1FZBC 3E1IC 2J3FD 1FZFB 2GY7A 2HLOC 4M7FA 1N73B 2J3OA 1LT9B 2Q9IB 2H43C 1RE3B 1RF0C 2J0HA 2HPCC 3BVHC 1FZEC 2J1GA 2FFDC 1FZAB 1N86B 2HODB 1M1JC 2JHMF 1JC9A 3HUSB 4R9JA 1Z3SA 1FZGC 2OYIC 1FIBA 2JHHC 2FIBA 2WNPF 2HLOB 2H43B 1RF0B 1RE4B 2HPCB 1RF1C 2J3FA 3BVHB 1FZEB 2Z4EC 2FFDB 4NYTA 2J60A 1LTJC 2OYHB 1FZCC 3GHGC 3FIBA 1FZDA 1FZGB 1Z3UA 1FZBB 2J64A 3E1IB 4EPUA 2JHIF 4ZFGA 1RF1B 3H32C 2D39A 4JZCA 1N73C 1RE3C 2Z4EB 2J5ZA 4R9TA 1LTJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J61 B;  1LWU C;  1FZC B;  1M1J B;  1FZA C;  2XNX C;  1N86 C;  2J61 A;  2J0Y A;  2J0G A;  2OYI B;  1FID A;  2J2P A;  3H32 B;  1FZF C;  1FIC A;  1RE4 C;  1LT9 C;  2Q9I C;  2JHL F;  1LWU B;  4JYO X;  2XNX B;  2J3U A;  2JHK F;  2J3G A;  2OYH C;  4M7H A;  2HOD C;  3HUS C;  1FZB C;  3E1I C;  2J3F D;  1FZF B;  2GY7 A;  2HLO C;  4M7F A;  1N73 B;  2J3O A;  1LT9 B;  2Q9I B;  2H43 C;  1RE3 B;  1RF0 C;  2J0H A;  2HPC C;  3BVH C;  1FZE C;  2J1G A;  2FFD C;  1FZA B;  1N86 B;  2HOD B;  1M1J C;  2JHM F;  1JC9 A;  3HUS B;  4R9J A;  1Z3S A;  1FZG C;  2OYI C;  1FIB A;  2JHH C;  2FIB A;  2WNP F;  2HLO B;  2H43 B;  1RF0 B;  1RE4 B;  2HPC B;  1RF1 C;  2J3F A;  3BVH B;  1FZE B;  2Z4E C;  2FFD B;  4NYT A;  2J60 A;  1LTJ C;  2OYH B;  1FZC C;  3GHG C;  3FIB A;  1FZD A;  1FZG B;  1Z3U A;  1FZB B;  2J64 A;  3E1I B;  4EPU A;  2JHI F;  4ZFG A;  1RF1 B;  3H32 C;  2D39 A;  4JZC A;  1N73 C;  1RE3 C;  2Z4E B;  2J5Z A;  4R9T A;  1LTJ B; 
#chains in the Genus database with same CATH topology
 2J61 B;  1LWU C;  1FZC B;  1M1J B;  1FZA C;  2XNX C;  1N86 C;  3GHG B;  2J61 A;  2J0Y A;  2J0G A;  2OYI B;  1FID A;  2J2P A;  3H32 B;  1FZF C;  1FIC A;  1RE4 C;  1LT9 C;  2Q9I C;  2JHL F;  1LWU B;  4JYO X;  2XNX B;  2J3U A;  2JHK F;  2J3G A;  2OYH C;  4M7H A;  2HOD C;  3HUS C;  1FZB C;  3E1I C;  2J3F D;  1FZF B;  2GY7 A;  2HLO C;  4M7F A;  1N73 B;  2J3O A;  1LT9 B;  2Q9I B;  2H43 C;  1RE3 B;  1RF0 C;  2J0H A;  2HPC C;  3BVH C;  1FZE C;  2J1G A;  2FFD C;  1FZA B;  1N86 B;  2HOD B;  1M1J C;  2JHM F;  1JC9 A;  3HUS B;  4R9J A;  1Z3S A;  1FZG C;  2OYI C;  1FIB A;  2JHH C;  2FIB A;  2WNP F;  2HLO B;  2H43 B;  1RF0 B;  1RE4 B;  2HPC B;  1RF1 C;  2J3F A;  3BVH B;  1FZE B;  2Z4E C;  2FFD B;  4NYT A;  2J60 A;  1LTJ C;  2OYH B;  1FZC C;  3GHG C;  3FIB A;  1FZD A;  1FZG B;  1Z3U A;  1FZB B;  2J64 A;  3E1I B;  4EPU A;  2JHI F;  4ZFG A;  1RF1 B;  3H32 C;  2D39 A;  4JZC A;  1N73 C;  1RE3 C;  2Z4E B;  2J5Z A;  4R9T A;  1LTJ B; 
#chains in the Genus database with same CATH homology
 2J61 B;  1LWU C;  1FZC B;  1M1J B;  1FZA C;  2XNX C;  1N86 C;  2J61 A;  2J0Y A;  2J0G A;  2OYI B;  1FID A;  2J2P A;  3H32 B;  1FZF C;  1FIC A;  1RE4 C;  1LT9 C;  2Q9I C;  2JHL F;  1LWU B;  4JYO X;  2XNX B;  2J3U A;  2JHK F;  2J3G A;  2OYH C;  4M7H A;  2HOD C;  3HUS C;  1FZB C;  3E1I C;  2J3F D;  1FZF B;  2GY7 A;  2HLO C;  4M7F A;  1N73 B;  2J3O A;  1LT9 B;  2Q9I B;  2H43 C;  1RE3 B;  1RF0 C;  2J0H A;  2HPC C;  3BVH C;  1FZE C;  2J1G A;  2FFD C;  1FZA B;  1N86 B;  2HOD B;  1M1J C;  2JHM F;  1JC9 A;  3HUS B;  4R9J A;  1Z3S A;  1FZG C;  2OYI C;  1FIB A;  2JHH C;  2FIB A;  2WNP F;  2HLO B;  2H43 B;  1RF0 B;  1RE4 B;  2HPC B;  1RF1 C;  2J3F A;  3BVH B;  1FZE B;  2Z4E C;  2FFD B;  4NYT A;  2J60 A;  1LTJ C;  2OYH B;  1FZC C;  3GHG C;  3FIB A;  1FZD A;  1FZG B;  1Z3U A;  1FZB B;  2J64 A;  3E1I B;  4EPU A;  2JHI F;  4ZFG A;  1RF1 B;  3H32 C;  2D39 A;  4JZC A;  1N73 C;  1RE3 C;  2Z4E B;  2J5Z A;  4R9T A;  1LTJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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