1RF0B

Crystal structure of fragment d of gammae132a fibrinogen
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
306
structure length
306
Chain Sequence
DETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calcium-Binding Site beta2, Adjacent to the "b" Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization.
pubmed doi rcsb
molecule tags Blood clotting
source organism Homo sapiens
molecule keywords Fibrinogen alpha/alpha-E chain
total genus 100
structure length 306
sequence length 306
chains with identical sequence E
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00147 Fibrinogen_C Fibrinogen beta and gamma chains, C-terminal globular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.215.10 Alpha Beta Alpha-Beta Complex Gamma Fibrinogen; Chain A, domain 1 Gamma Fibrinogen, chain A, domain 1 1rf0B01
4.10.530.10 Few Secondary Structures Irregular Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2 Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 1rf0B02
2OYHC 3H32C 1FZBC 2HLOB 3BVHC 2J1GA 2J2PA 1FZEC 2HODC 1FZFC 2Z4EB 1RF0B 2J61B 3HUSB 2J61A 1FIBA 1FZGB 4JZCA 1Z3UA 1RE3C 2FFDC 1FZAB 1LWUC 2JHMF 2GY7A 2J3UA 3GHGC 2H43B 1RF1C 1LTJB 1FICA 1JC9A 2WNPF 4JYOX 1LT9B 2J5ZA 2OYHB 3H32B 1M1JC 1FZCC 1N86C 1FZBB 3BVHB 1FZEB 2HODB 1FZFB 4ZFGA 2OYIC 2HPCC 1Z3SA 2J3GA 2Q9IC 1N73C 1RE3B 2J3FD 2JHHC 1RE4C 4NYTA 4EPUA 2XNXC 4R9JA 2FFDB 1LWUB 1RF1B 3E1IC 2D39A 2FIBA 2J64A 2J0YA 1M1JB 1FZCB 2HLOC 1N86B 2J0HA 4R9TA 2JHLF 2Z4EC 1RF0C 3HUSC 1FIDA 2J3FA 1FZGC 3FIBA 2OYIB 2HPCB 2Q9IB 1N73B 2J3OA 1RE4B 2JHIF 1FZDA 1FZAC 2J0GA 2XNXB 4M7FA 4M7HA 2H43C 1LTJC 2JHKF 3E1IB 2J60A 1LT9C
chains in the Genus database with same CATH superfamily
2OYHC 3H32C 1FZBC 2HLOB 3BVHC 2J1GA 2J2PA 1FZEC 2HODC 1FZFC 2Z4EB 1RF0B 2J61B 3HUSB 2J61A 1FIBA 1FZGB 4JZCA 1Z3UA 1RE3C 2FFDC 1FZAB 1LWUC 2JHMF 2GY7A 2J3UA 3GHGC 2H43B 1RF1C 1LTJB 1FICA 1JC9A 2WNPF 4JYOX 1LT9B 2J5ZA 2OYHB 3H32B 1M1JC 1FZCC 1N86C 1FZBB 3BVHB 1FZEB 2HODB 1FZFB 4ZFGA 2OYIC 1Z3SA 2J3GA 2HPCC 2Q9IC 1N73C 1RE3B 2J3FD 2JHHC 1RE4C 4NYTA 4EPUA 2XNXC 4R9JA 2FFDB 1LWUB 3GHGB 1RF1B 3E1IC 2D39A 2FIBA 2J64A 2J0YA 1M1JB 1FZCB 2HLOC 1N86B 2J0HA 4R9TA 2JHLF 2Z4EC 1RF0C 3HUSC 1FIDA 2J3FA 1FZGC 3FIBA 2OYIB 2HPCB 2Q9IB 1N73B 2J3OA 1RE4B 2JHIF 1FZDA 1FZAC 2J0GA 2XNXB 4M7FA 4M7HA 2H43C 1LTJC 2JHKF 3E1IB 2J60A 1LT9C
chains in the Genus database with same CATH topology
2OYHC 3H32C 1FZBC 2HLOB 3BVHC 2J1GA 2J2PA 1FZEC 2HODC 1FZFC 2Z4EB 1RF0B 2J61B 3HUSB 2J61A 1FIBA 1FZGB 4JZCA 1Z3UA 1RE3C 2FFDC 1FZAB 1LWUC 2JHMF 2GY7A 2J3UA 3GHGC 2H43B 1RF1C 1LTJB 1FICA 1JC9A 2WNPF 4JYOX 1LT9B 2J5ZA 2OYHB 3H32B 1M1JC 1FZCC 1N86C 1FZBB 3BVHB 1FZEB 2HODB 1FZFB 4ZFGA 2OYIC 2HPCC 1Z3SA 2J3GA 2Q9IC 1N73C 1RE3B 2J3FD 2JHHC 1RE4C 4NYTA 4EPUA 2XNXC 4R9JA 2FFDB 1LWUB 1RF1B 3E1IC 2D39A 2FIBA 2J64A 2J0YA 1M1JB 1FZCB 2HLOC 1N86B 2J0HA 4R9TA 2JHLF 2Z4EC 1RF0C 3HUSC 1FIDA 2J3FA 1FZGC 3FIBA 2OYIB 2HPCB 2Q9IB 1N73B 2J3OA 1RE4B 2JHIF 1FZDA 1FZAC 2J0GA 2XNXB 4M7FA 4M7HA 2H43C 1LTJC 2JHKF 3E1IB 2J60A 1LT9C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OYH C;  3H32 C;  1FZB C;  2HLO B;  3BVH C;  2J1G A;  2J2P A;  1FZE C;  2HOD C;  1FZF C;  2Z4E B;  1RF0 B;  2J61 B;  3HUS B;  2J61 A;  1FIB A;  1FZG B;  4JZC A;  1Z3U A;  1RE3 C;  2FFD C;  1FZA B;  1LWU C;  2JHM F;  2GY7 A;  2J3U A;  3GHG C;  2H43 B;  1RF1 C;  1LTJ B;  1FIC A;  1JC9 A;  2WNP F;  4JYO X;  1LT9 B;  2J5Z A;  2OYH B;  3H32 B;  1M1J C;  1FZC C;  1N86 C;  1FZB B;  3BVH B;  1FZE B;  2HOD B;  1FZF B;  4ZFG A;  2OYI C;  2HPC C;  1Z3S A;  2J3G A;  2Q9I C;  1N73 C;  1RE3 B;  2J3F D;  2JHH C;  1RE4 C;  4NYT A;  4EPU A;  2XNX C;  4R9J A;  2FFD B;  1LWU B;  1RF1 B;  3E1I C;  2D39 A;  2FIB A;  2J64 A;  2J0Y A;  1M1J B;  1FZC B;  2HLO C;  1N86 B;  2J0H A;  4R9T A;  2JHL F;  2Z4E C;  1RF0 C;  3HUS C;  1FID A;  2J3F A;  1FZG C;  3FIB A;  2OYI B;  2HPC B;  2Q9I B;  1N73 B;  2J3O A;  1RE4 B;  2JHI F;  1FZD A;  1FZA C;  2J0G A;  2XNX B;  4M7F A;  4M7H A;  2H43 C;  1LTJ C;  2JHK F;  3E1I B;  2J60 A;  1LT9 C; 
#chains in the Genus database with same CATH topology
 2OYH C;  3H32 C;  1FZB C;  2HLO B;  3BVH C;  2J1G A;  2J2P A;  1FZE C;  2HOD C;  1FZF C;  2Z4E B;  1RF0 B;  2J61 B;  3HUS B;  2J61 A;  1FIB A;  1FZG B;  4JZC A;  1Z3U A;  1RE3 C;  2FFD C;  1FZA B;  1LWU C;  2JHM F;  2GY7 A;  2J3U A;  3GHG C;  2H43 B;  1RF1 C;  1LTJ B;  1FIC A;  1JC9 A;  2WNP F;  4JYO X;  1LT9 B;  2J5Z A;  2OYH B;  3H32 B;  1M1J C;  1FZC C;  1N86 C;  1FZB B;  3BVH B;  1FZE B;  2HOD B;  1FZF B;  4ZFG A;  2OYI C;  1Z3S A;  2J3G A;  2HPC C;  2Q9I C;  1N73 C;  1RE3 B;  2J3F D;  2JHH C;  1RE4 C;  4NYT A;  4EPU A;  2XNX C;  4R9J A;  2FFD B;  1LWU B;  3GHG B;  1RF1 B;  3E1I C;  2D39 A;  2FIB A;  2J64 A;  2J0Y A;  1M1J B;  1FZC B;  2HLO C;  1N86 B;  2J0H A;  4R9T A;  2JHL F;  2Z4E C;  1RF0 C;  3HUS C;  1FID A;  2J3F A;  1FZG C;  3FIB A;  2OYI B;  2HPC B;  2Q9I B;  1N73 B;  2J3O A;  1RE4 B;  2JHI F;  1FZD A;  1FZA C;  2J0G A;  2XNX B;  4M7F A;  4M7H A;  2H43 C;  1LTJ C;  2JHK F;  3E1I B;  2J60 A;  1LT9 C; 
#chains in the Genus database with same CATH homology
 2OYH C;  3H32 C;  1FZB C;  2HLO B;  3BVH C;  2J1G A;  2J2P A;  1FZE C;  2HOD C;  1FZF C;  2Z4E B;  1RF0 B;  2J61 B;  3HUS B;  2J61 A;  1FIB A;  1FZG B;  4JZC A;  1Z3U A;  1RE3 C;  2FFD C;  1FZA B;  1LWU C;  2JHM F;  2GY7 A;  2J3U A;  3GHG C;  2H43 B;  1RF1 C;  1LTJ B;  1FIC A;  1JC9 A;  2WNP F;  4JYO X;  1LT9 B;  2J5Z A;  2OYH B;  3H32 B;  1M1J C;  1FZC C;  1N86 C;  1FZB B;  3BVH B;  1FZE B;  2HOD B;  1FZF B;  4ZFG A;  2OYI C;  2HPC C;  1Z3S A;  2J3G A;  2Q9I C;  1N73 C;  1RE3 B;  2J3F D;  2JHH C;  1RE4 C;  4NYT A;  4EPU A;  2XNX C;  4R9J A;  2FFD B;  1LWU B;  1RF1 B;  3E1I C;  2D39 A;  2FIB A;  2J64 A;  2J0Y A;  1M1J B;  1FZC B;  2HLO C;  1N86 B;  2J0H A;  4R9T A;  2JHL F;  2Z4E C;  1RF0 C;  3HUS C;  1FID A;  2J3F A;  1FZG C;  3FIB A;  2OYI B;  2HPC B;  2Q9I B;  1N73 B;  2J3O A;  1RE4 B;  2JHI F;  1FZD A;  1FZA C;  2J0G A;  2XNX B;  4M7F A;  4M7H A;  2H43 C;  1LTJ C;  2JHK F;  3E1I B;  2J60 A;  1LT9 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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