1T8LB

Crystal structure of the p1 met bpti mutant- bovine chymotrypsin complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
59
structure length
59
Chain Sequence
MRPDFCLEPPYTGPCMARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords Chymotrypsin A
total genus 11
structure length 59
sequence length 59
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1t8lB00
2HEXA 3L33E 1P2OB 3AUBA 1BIKA 3FP8I 3WNYA 4DTGK 1OA65 1KUNA 4Y0YI 1TAWB 5JB7A 3LDMA 3BTGI 2ZVXA 3BTMI 3TPII 1T8OB 3LDJA 1UUBA 2DDIA 1BRBI 1MTND 2CA7A 1YLCB 3FP7J 5JB6A 2IJOI 6PTIA 3UOUB 1CO7I 2TGPI 3BTDI 3AUGA 1ADZA 1D0DB 4Y11I 8PTIA 2UUYB 2W8XA 3BYBA 1BF0A 2FI4I 3OFWA 1ZR0B 4PTIA 1DTXA 3FP6I 1KNTA 2M01A 3P95E 2FI3I 2TPII 3D65I 4WXVC 2R9PE 3L3TE 1T8LB 5C67C 2FI5I 1Y62A 2M99A 3TGII 3UIRC 1P2II 1TOCR 3OTJI 1LD5A 5PTIA 1DEMA 3T62D 2UUXA 1AAPA 1T8NB 1DENA 1TCPA 4Y0ZI 1T7CB 1K6UA 4U30W 4DG4C 3BTKI 1P2JI 3LDIA 7PTIA 1P2MB 2ZJXA 1F7ZI 3GYMI 3BTWI 4BD9B 4BNRI 1UUAA 3CI7A 1KTHA 2J6DA 1TAPA 3AUIA 2ODYE 1BTHP 3P92E 1P2NB 1ZJDB 4ISLB 1LD6A 3BTFI 1TPAI 1EAWB 1YC0I 1FANA 1BHCA 1YKTB 4TPII 1P2QB 1BUNB 1AALA 1F5RI 3BTQI 2LFKA 4NTWB 1BRCI 4ISOB 3U1JE 3BTEI 1SHPA 2KCRA 1FAKI 1BZ5A 1QLQA 1BPTA 1FY8I 1KIGI 2JOTA 2RA3C 3AUDA 2DDJA 2FTLI 1DTKA 1JC6A 3M7QB 1CA0D 3TGJI 1PITA 2KAII 9PTIA 4BQDA 4NTXB 1BPIA 5JB5A 1T8MB 4U32X 3AUEA 1B0CA 1P2KI 3AUCA 2LFLA 1EJMB 2FTMB 2KNTA 4ISNB 4Y10I 1CBWD 3AUHA 1TFXC 1YLDB 3TGKI 1OA55 4WWYC 2PTCI 5JB4A 4NTYB 1BZXI 1NAGA 3BTTI 3BTHI 1IRHA 1D0DA 1JV9A 1BTIA 1JV8A 1G6XA
chains in the Genus database with same CATH superfamily
2HEXA 3L33E 1P2OB 3AUBA 1BIKA 3FP8I 3WNYA 4DTGK 1OA65 1KUNA 4Y0YI 1TAWB 5JB7A 3LDMA 3BTGI 2ZVXA 3BTMI 3TPII 1T8OB 3LDJA 1UUBA 2DDIA 1BRBI 1MTND 2CA7A 1YLCB 3FP7J 5JB6A 2IJOI 6PTIA 3UOUB 1CO7I 2TGPI 3BTDI 3AUGA 1ADZA 1D0DB 4Y11I 8PTIA 2UUYB 2W8XA 3BYBA 1BF0A 2FI4I 3OFWA 1ZR0B 4PTIA 1DTXA 3FP6I 1KNTA 2M01A 3P95E 2FI3I 2TPII 3D65I 4WXVC 2R9PE 3L3TE 1T8LB 5C67C 2FI5I 1Y62A 2M99A 3TGII 3UIRC 1P2II 1TOCR 3OTJI 1LD5A 5PTIA 1DEMA 3T62D 2UUXA 1AAPA 1T8NB 1DENA 1TCPA 4Y0ZI 1T7CB 1K6UA 4U30W 4DG4C 3BTKI 1P2JI 3LDIA 7PTIA 1P2MB 2ZJXA 1F7ZI 3GYMI 3BTWI 4BD9B 4BNRI 1UUAA 3CI7A 1KTHA 2J6DA 1TAPA 3AUIA 2ODYE 1BTHP 3P92E 1P2NB 1ZJDB 4ISLB 1LD6A 3BTFI 1TPAI 1EAWB 1YC0I 1FANA 1BHCA 1YKTB 4TPII 1P2QB 1BUNB 1AALA 1F5RI 3BTQI 2LFKA 4NTWB 1BRCI 4ISOB 3U1JE 3BTEI 1SHPA 2KCRA 1FAKI 1BZ5A 1QLQA 1BPTA 1FY8I 1KIGI 2JOTA 2RA3C 3AUDA 2DDJA 2FTLI 1DTKA 1JC6A 3M7QB 1CA0D 3TGJI 1PITA 2KAII 9PTIA 4BQDA 4NTXB 1BPIA 5JB5A 1T8MB 4U32X 3AUEA 1B0CA 1P2KI 3AUCA 2LFLA 1EJMB 2FTMB 2KNTA 4ISNB 4Y10I 1CBWD 3AUHA 1TFXC 1YLDB 3TGKI 1OA55 4WWYC 2PTCI 5JB4A 4NTYB 1BZXI 1NAGA 3BTTI 3BTHI 1IRHA 1D0DA 1JV9A 1BTIA 1JV8A 1G6XA
chains in the Genus database with same CATH topology
2HEXA 3L33E 1P2OB 3AUBA 1BIKA 3FP8I 3WNYA 4DTGK 1OA65 1KUNA 4Y0YI 1TAWB 5JB7A 3LDMA 3BTGI 2ZVXA 3BTMI 3TPII 1T8OB 3LDJA 1UUBA 2DDIA 1BRBI 1MTND 2CA7A 1YLCB 3FP7J 5JB6A 2IJOI 6PTIA 3UOUB 1CO7I 2TGPI 3BTDI 3AUGA 1ADZA 1D0DB 4Y11I 8PTIA 2UUYB 2W8XA 3BYBA 1BF0A 2FI4I 3OFWA 1ZR0B 4PTIA 1DTXA 3FP6I 1KNTA 2M01A 3P95E 2FI3I 2TPII 3D65I 4WXVC 2R9PE 3L3TE 1T8LB 5C67C 2FI5I 1Y62A 2M99A 3TGII 3UIRC 1P2II 1TOCR 3OTJI 1LD5A 5PTIA 1DEMA 3T62D 2UUXA 1AAPA 1T8NB 1DENA 1TCPA 4Y0ZI 1T7CB 1K6UA 4U30W 4DG4C 3BTKI 1P2JI 3LDIA 7PTIA 1P2MB 2ZJXA 1F7ZI 3GYMI 3BTWI 4BD9B 4BNRI 1UUAA 3CI7A 1KTHA 2J6DA 1TAPA 3AUIA 2ODYE 1BTHP 3P92E 1P2NB 1ZJDB 4ISLB 1LD6A 3BTFI 1TPAI 1EAWB 1YC0I 1FANA 1BHCA 1YKTB 4TPII 1P2QB 1BUNB 1AALA 1F5RI 3BTQI 2LFKA 4NTWB 1BRCI 4ISOB 3U1JE 3BTEI 1SHPA 2KCRA 1FAKI 1BZ5A 1QLQA 1BPTA 1FY8I 1KIGI 2JOTA 2RA3C 3AUDA 2DDJA 2FTLI 1DTKA 1JC6A 3M7QB 1CA0D 3TGJI 1PITA 2KAII 9PTIA 4BQDA 4NTXB 1BPIA 5JB5A 1T8MB 4U32X 3AUEA 1B0CA 1P2KI 3AUCA 2LFLA 1EJMB 2FTMB 2KNTA 4ISNB 4Y10I 1CBWD 3AUHA 1TFXC 1YLDB 3TGKI 1OA55 4WWYC 2PTCI 5JB4A 4NTYB 1BZXI 1NAGA 3BTTI 3BTHI 1IRHA 1D0DA 1JV9A 1BTIA 1JV8A 1G6XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HEX A;  3L33 E;  1P2O B;  3AUB A;  1BIK A;  3FP8 I;  3WNY A;  4DTG K;  1OA6 5;  1KUN A;  4Y0Y I;  1TAW B;  5JB7 A;  3LDM A;  3BTG I;  2ZVX A;  3BTM I;  3TPI I;  1T8O B;  3LDJ A;  1UUB A;  2DDI A;  1BRB I;  1MTN D;  2CA7 A;  1YLC B;  3FP7 J;  5JB6 A;  2IJO I;  6PTI A;  3UOU B;  1CO7 I;  2TGP I;  3BTD I;  3AUG A;  1ADZ A;  1D0D B;  4Y11 I;  8PTI A;  2UUY B;  2W8X A;  3BYB A;  1BF0 A;  2FI4 I;  3OFW A;  1ZR0 B;  4PTI A;  1DTX A;  3FP6 I;  1KNT A;  2M01 A;  3P95 E;  2FI3 I;  2TPI I;  3D65 I;  4WXV C;  2R9P E;  3L3T E;  1T8L B;  5C67 C;  2FI5 I;  1Y62 A;  2M99 A;  3TGI I;  3UIR C;  1P2I I;  1TOC R;  3OTJ I;  1LD5 A;  5PTI A;  1DEM A;  3T62 D;  2UUX A;  1AAP A;  1T8N B;  1DEN A;  1TCP A;  4Y0Z I;  1T7C B;  1K6U A;  4U30 W;  4DG4 C;  3BTK I;  1P2J I;  3LDI A;  7PTI A;  1P2M B;  2ZJX A;  1F7Z I;  3GYM I;  3BTW I;  4BD9 B;  4BNR I;  1UUA A;  3CI7 A;  1KTH A;  2J6D A;  1TAP A;  3AUI A;  2ODY E;  1BTH P;  3P92 E;  1P2N B;  1ZJD B;  4ISL B;  1LD6 A;  3BTF I;  1TPA I;  1EAW B;  1YC0 I;  1FAN A;  1BHC A;  1YKT B;  4TPI I;  1P2Q B;  1BUN B;  1AAL A;  1F5R I;  3BTQ I;  2LFK A;  4NTW B;  1BRC I;  4ISO B;  3U1J E;  3BTE I;  1SHP A;  2KCR A;  1FAK I;  1BZ5 A;  1QLQ A;  1BPT A;  1FY8 I;  1KIG I;  2JOT A;  2RA3 C;  3AUD A;  2DDJ A;  2FTL I;  1DTK A;  1JC6 A;  3M7Q B;  1CA0 D;  3TGJ I;  1PIT A;  2KAI I;  9PTI A;  4BQD A;  4NTX B;  1BPI A;  5JB5 A;  1T8M B;  4U32 X;  3AUE A;  1B0C A;  1P2K I;  3AUC A;  2LFL A;  1EJM B;  2FTM B;  2KNT A;  4ISN B;  4Y10 I;  1CBW D;  3AUH A;  1TFX C;  1YLD B;  3TGK I;  1OA5 5;  4WWY C;  2PTC I;  5JB4 A;  4NTY B;  1BZX I;  1NAG A;  3BTT I;  3BTH I;  1IRH A;  1D0D A;  1JV9 A;  1BTI A;  1JV8 A;  1G6X A; 
#chains in the Genus database with same CATH topology
 2HEX A;  3L33 E;  1P2O B;  3AUB A;  1BIK A;  3FP8 I;  3WNY A;  4DTG K;  1OA6 5;  1KUN A;  4Y0Y I;  1TAW B;  5JB7 A;  3LDM A;  3BTG I;  2ZVX A;  3BTM I;  3TPI I;  1T8O B;  3LDJ A;  1UUB A;  2DDI A;  1BRB I;  1MTN D;  2CA7 A;  1YLC B;  3FP7 J;  5JB6 A;  2IJO I;  6PTI A;  3UOU B;  1CO7 I;  2TGP I;  3BTD I;  3AUG A;  1ADZ A;  1D0D B;  4Y11 I;  8PTI A;  2UUY B;  2W8X A;  3BYB A;  1BF0 A;  2FI4 I;  3OFW A;  1ZR0 B;  4PTI A;  1DTX A;  3FP6 I;  1KNT A;  2M01 A;  3P95 E;  2FI3 I;  2TPI I;  3D65 I;  4WXV C;  2R9P E;  3L3T E;  1T8L B;  5C67 C;  2FI5 I;  1Y62 A;  2M99 A;  3TGI I;  3UIR C;  1P2I I;  1TOC R;  3OTJ I;  1LD5 A;  5PTI A;  1DEM A;  3T62 D;  2UUX A;  1AAP A;  1T8N B;  1DEN A;  1TCP A;  4Y0Z I;  1T7C B;  1K6U A;  4U30 W;  4DG4 C;  3BTK I;  1P2J I;  3LDI A;  7PTI A;  1P2M B;  2ZJX A;  1F7Z I;  3GYM I;  3BTW I;  4BD9 B;  4BNR I;  1UUA A;  3CI7 A;  1KTH A;  2J6D A;  1TAP A;  3AUI A;  2ODY E;  1BTH P;  3P92 E;  1P2N B;  1ZJD B;  4ISL B;  1LD6 A;  3BTF I;  1TPA I;  1EAW B;  1YC0 I;  1FAN A;  1BHC A;  1YKT B;  4TPI I;  1P2Q B;  1BUN B;  1AAL A;  1F5R I;  3BTQ I;  2LFK A;  4NTW B;  1BRC I;  4ISO B;  3U1J E;  3BTE I;  1SHP A;  2KCR A;  1FAK I;  1BZ5 A;  1QLQ A;  1BPT A;  1FY8 I;  1KIG I;  2JOT A;  2RA3 C;  3AUD A;  2DDJ A;  2FTL I;  1DTK A;  1JC6 A;  3M7Q B;  1CA0 D;  3TGJ I;  1PIT A;  2KAI I;  9PTI A;  4BQD A;  4NTX B;  1BPI A;  5JB5 A;  1T8M B;  4U32 X;  3AUE A;  1B0C A;  1P2K I;  3AUC A;  2LFL A;  1EJM B;  2FTM B;  2KNT A;  4ISN B;  4Y10 I;  1CBW D;  3AUH A;  1TFX C;  1YLD B;  3TGK I;  1OA5 5;  4WWY C;  2PTC I;  5JB4 A;  4NTY B;  1BZX I;  1NAG A;  3BTT I;  3BTH I;  1IRH A;  1D0D A;  1JV9 A;  1BTI A;  1JV8 A;  1G6X A; 
#chains in the Genus database with same CATH homology
 2HEX A;  3L33 E;  1P2O B;  3AUB A;  1BIK A;  3FP8 I;  3WNY A;  4DTG K;  1OA6 5;  1KUN A;  4Y0Y I;  1TAW B;  5JB7 A;  3LDM A;  3BTG I;  2ZVX A;  3BTM I;  3TPI I;  1T8O B;  3LDJ A;  1UUB A;  2DDI A;  1BRB I;  1MTN D;  2CA7 A;  1YLC B;  3FP7 J;  5JB6 A;  2IJO I;  6PTI A;  3UOU B;  1CO7 I;  2TGP I;  3BTD I;  3AUG A;  1ADZ A;  1D0D B;  4Y11 I;  8PTI A;  2UUY B;  2W8X A;  3BYB A;  1BF0 A;  2FI4 I;  3OFW A;  1ZR0 B;  4PTI A;  1DTX A;  3FP6 I;  1KNT A;  2M01 A;  3P95 E;  2FI3 I;  2TPI I;  3D65 I;  4WXV C;  2R9P E;  3L3T E;  1T8L B;  5C67 C;  2FI5 I;  1Y62 A;  2M99 A;  3TGI I;  3UIR C;  1P2I I;  1TOC R;  3OTJ I;  1LD5 A;  5PTI A;  1DEM A;  3T62 D;  2UUX A;  1AAP A;  1T8N B;  1DEN A;  1TCP A;  4Y0Z I;  1T7C B;  1K6U A;  4U30 W;  4DG4 C;  3BTK I;  1P2J I;  3LDI A;  7PTI A;  1P2M B;  2ZJX A;  1F7Z I;  3GYM I;  3BTW I;  4BD9 B;  4BNR I;  1UUA A;  3CI7 A;  1KTH A;  2J6D A;  1TAP A;  3AUI A;  2ODY E;  1BTH P;  3P92 E;  1P2N B;  1ZJD B;  4ISL B;  1LD6 A;  3BTF I;  1TPA I;  1EAW B;  1YC0 I;  1FAN A;  1BHC A;  1YKT B;  4TPI I;  1P2Q B;  1BUN B;  1AAL A;  1F5R I;  3BTQ I;  2LFK A;  4NTW B;  1BRC I;  4ISO B;  3U1J E;  3BTE I;  1SHP A;  2KCR A;  1FAK I;  1BZ5 A;  1QLQ A;  1BPT A;  1FY8 I;  1KIG I;  2JOT A;  2RA3 C;  3AUD A;  2DDJ A;  2FTL I;  1DTK A;  1JC6 A;  3M7Q B;  1CA0 D;  3TGJ I;  1PIT A;  2KAI I;  9PTI A;  4BQD A;  4NTX B;  1BPI A;  5JB5 A;  1T8M B;  4U32 X;  3AUE A;  1B0C A;  1P2K I;  3AUC A;  2LFL A;  1EJM B;  2FTM B;  2KNT A;  4ISN B;  4Y10 I;  1CBW D;  3AUH A;  1TFX C;  1YLD B;  3TGK I;  1OA5 5;  4WWY C;  2PTC I;  5JB4 A;  4NTY B;  1BZX I;  1NAG A;  3BTT I;  3BTH I;  1IRH A;  1D0D A;  1JV9 A;  1BTI A;  1JV8 A;  1G6X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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