1T8MB

Crystal structure of the p1 his bpti mutant- bovine chymotrypsin complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCHARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords Chymotrypsin A
total genus 11
structure length 58
sequence length 58
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1t8mB00
1DEMA 4Y10I 1AAPA 3AUGA 4BQDA 2FTLI 3L33E 4NTYB 5JB6A 1JV9A 3BTEI 1YLDB 4U30W 1OA65 1BPIA 3AUEA 8PTIA 2KCRA 1SHPA 4TPII 1T8MB 4NTXB 4ISOB 4Y0YI 5C67C 3LDIA 1T8LB 1DENA 1T8NB 3AUIA 4DTGK 1BRBI 1CBWD 1BPTA 3AUBA 1FY8I 1IRHA 1MTND 1KUNA 1ZR0B 2DDIA 7PTIA 1DTXA 3U1JE 4BNRI 4U32X 2PTCI 3LDMA 1P2OB 1P2NB 2TPII 5JB7A 3OTJI 4ISNB 2ODYE 3AUHA 2LFKA 3BTTI 4ISLB 1QLQA 3BTKI 1ADZA 3BTFI 1P2MB 1TCPA 1G6XA 1BIKA 3WNYA 1KTHA 3TGJI 2J6DA 2KAII 3LDJA 1BZXI 2FI4I 1CO7I 1JC6A 2UUXA 2CA7A 4NTWB 1TOCR 1K6UA 3FP6I 1B0CA 1KNTA 1TFXC 2M01A 1OA55 2ZJXA 2TGPI 1TPAI 1YKTB 3D65I 4Y11I 1JV8A 1F7ZI 3TGKI 1P2II 1EAWB 1NAGA 3AUCA 4PTIA 1TAPA 2RA3C 1FAKI 1BF0A 1AALA 5JB4A 2HEXA 1ZJDB 5PTIA 1KIGI 1T8OB 2ZVXA 1P2JI 1TAWB 4BD9B 3BTWI 3CI7A 5JB5A 1Y62A 3FP7J 2DDJA 4Y0ZI 1T7CB 3TPII 1EJMB 1YC0I 2LFLA 3GYMI 1PITA 6PTIA 3BTGI 2KNTA 1P2QB 1FANA 3OFWA 3BTMI 1BHCA 2FTMB 1DTKA 1YLCB 4WXVC 2UUYB 3P92E 1BTHP 1P2KI 3BYBA 3UIRC 1BUNB 3BTQI 1BTIA 1LD5A 2FI3I 9PTIA 1D0DB 1LD6A 1F5RI 3AUDA 2W8XA 1CA0D 1BRCI 2JOTA 4DG4C 2FI5I 2IJOI 3T62D 4WWYC 3TGII 1D0DA 3P95E 3BTHI 1UUAA 1UUBA 3UOUB 2M99A 3L3TE 3BTDI 3M7QB 3FP8I 1BZ5A 2R9PE
chains in the Genus database with same CATH superfamily
1DEMA 4Y10I 1AAPA 3AUGA 4BQDA 2FTLI 3L33E 4NTYB 5JB6A 1JV9A 3BTEI 1YLDB 4U30W 1OA65 1BPIA 3AUEA 8PTIA 2KCRA 1SHPA 4TPII 1T8MB 4NTXB 4ISOB 4Y0YI 5C67C 3LDIA 1T8LB 1DENA 1T8NB 3AUIA 4DTGK 1BRBI 1CBWD 1BPTA 3AUBA 1FY8I 1IRHA 1MTND 1KUNA 1ZR0B 2DDIA 7PTIA 1DTXA 3U1JE 4BNRI 4U32X 2PTCI 3LDMA 1P2OB 1P2NB 2TPII 5JB7A 3OTJI 4ISNB 2ODYE 3AUHA 2LFKA 3BTTI 4ISLB 1QLQA 3BTKI 1ADZA 3BTFI 1P2MB 1TCPA 1G6XA 1BIKA 3WNYA 1KTHA 3TGJI 2J6DA 2KAII 3LDJA 1BZXI 2FI4I 1CO7I 1JC6A 2UUXA 2CA7A 4NTWB 1TOCR 1K6UA 3FP6I 1B0CA 1KNTA 1TFXC 2M01A 1OA55 2ZJXA 2TGPI 1TPAI 1YKTB 3D65I 4Y11I 1JV8A 1F7ZI 3TGKI 1P2II 1EAWB 1NAGA 3AUCA 4PTIA 1TAPA 2RA3C 1FAKI 1BF0A 1AALA 5JB4A 2HEXA 1ZJDB 5PTIA 1KIGI 1T8OB 2ZVXA 1P2JI 1TAWB 4BD9B 3BTWI 3CI7A 5JB5A 1Y62A 3FP7J 2DDJA 4Y0ZI 1T7CB 3TPII 1EJMB 1YC0I 2LFLA 3GYMI 1PITA 6PTIA 3BTGI 2KNTA 1P2QB 1FANA 3OFWA 3BTMI 1BHCA 2FTMB 1DTKA 1YLCB 4WXVC 2UUYB 3P92E 1BTHP 1P2KI 3BYBA 3UIRC 1BUNB 3BTQI 1BTIA 1LD5A 2FI3I 9PTIA 1D0DB 1LD6A 1F5RI 3AUDA 2W8XA 1CA0D 1BRCI 2JOTA 4DG4C 2FI5I 2IJOI 3T62D 4WWYC 3TGII 1D0DA 3P95E 3BTHI 1UUAA 1UUBA 3UOUB 2M99A 3L3TE 3BTDI 3M7QB 3FP8I 1BZ5A 2R9PE
chains in the Genus database with same CATH topology
1DEMA 4Y10I 1AAPA 3AUGA 4BQDA 2FTLI 3L33E 4NTYB 5JB6A 1JV9A 3BTEI 1YLDB 4U30W 1OA65 1BPIA 3AUEA 8PTIA 2KCRA 1SHPA 4TPII 1T8MB 4NTXB 4ISOB 4Y0YI 5C67C 3LDIA 1T8LB 1DENA 1T8NB 3AUIA 4DTGK 1BRBI 1CBWD 1BPTA 3AUBA 1FY8I 1IRHA 1MTND 1KUNA 1ZR0B 2DDIA 7PTIA 1DTXA 3U1JE 4BNRI 4U32X 2PTCI 3LDMA 1P2OB 1P2NB 2TPII 5JB7A 3OTJI 4ISNB 2ODYE 3AUHA 2LFKA 3BTTI 4ISLB 1QLQA 3BTKI 1ADZA 3BTFI 1P2MB 1TCPA 1G6XA 1BIKA 3WNYA 1KTHA 3TGJI 2J6DA 2KAII 3LDJA 1BZXI 2FI4I 1CO7I 1JC6A 2UUXA 2CA7A 4NTWB 1TOCR 1K6UA 3FP6I 1B0CA 1KNTA 1TFXC 2M01A 1OA55 2ZJXA 2TGPI 1TPAI 1YKTB 3D65I 4Y11I 1JV8A 1F7ZI 3TGKI 1P2II 1EAWB 1NAGA 3AUCA 4PTIA 1TAPA 2RA3C 1FAKI 1BF0A 1AALA 5JB4A 2HEXA 1ZJDB 5PTIA 1KIGI 1T8OB 2ZVXA 1P2JI 1TAWB 4BD9B 3BTWI 3CI7A 5JB5A 1Y62A 3FP7J 2DDJA 4Y0ZI 1T7CB 3TPII 1EJMB 1YC0I 2LFLA 3GYMI 1PITA 6PTIA 3BTGI 2KNTA 1P2QB 1FANA 3OFWA 3BTMI 1BHCA 2FTMB 1DTKA 1YLCB 4WXVC 2UUYB 3P92E 1BTHP 1P2KI 3BYBA 3UIRC 1BUNB 3BTQI 1BTIA 1LD5A 2FI3I 9PTIA 1D0DB 1LD6A 1F5RI 3AUDA 2W8XA 1CA0D 1BRCI 2JOTA 4DG4C 2FI5I 2IJOI 3T62D 4WWYC 3TGII 1D0DA 3P95E 3BTHI 1UUAA 1UUBA 3UOUB 2M99A 3L3TE 3BTDI 3M7QB 3FP8I 1BZ5A 2R9PE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DEM A;  4Y10 I;  1AAP A;  3AUG A;  4BQD A;  2FTL I;  3L33 E;  4NTY B;  5JB6 A;  1JV9 A;  3BTE I;  1YLD B;  4U30 W;  1OA6 5;  1BPI A;  3AUE A;  8PTI A;  2KCR A;  1SHP A;  4TPI I;  1T8M B;  4NTX B;  4ISO B;  4Y0Y I;  5C67 C;  3LDI A;  1T8L B;  1DEN A;  1T8N B;  3AUI A;  4DTG K;  1BRB I;  1CBW D;  1BPT A;  3AUB A;  1FY8 I;  1IRH A;  1MTN D;  1KUN A;  1ZR0 B;  2DDI A;  7PTI A;  1DTX A;  3U1J E;  4BNR I;  4U32 X;  2PTC I;  3LDM A;  1P2O B;  1P2N B;  2TPI I;  5JB7 A;  3OTJ I;  4ISN B;  2ODY E;  3AUH A;  2LFK A;  3BTT I;  4ISL B;  1QLQ A;  3BTK I;  1ADZ A;  3BTF I;  1P2M B;  1TCP A;  1G6X A;  1BIK A;  3WNY A;  1KTH A;  3TGJ I;  2J6D A;  2KAI I;  3LDJ A;  1BZX I;  2FI4 I;  1CO7 I;  1JC6 A;  2UUX A;  2CA7 A;  4NTW B;  1TOC R;  1K6U A;  3FP6 I;  1B0C A;  1KNT A;  1TFX C;  2M01 A;  1OA5 5;  2ZJX A;  2TGP I;  1TPA I;  1YKT B;  3D65 I;  4Y11 I;  1JV8 A;  1F7Z I;  3TGK I;  1P2I I;  1EAW B;  1NAG A;  3AUC A;  4PTI A;  1TAP A;  2RA3 C;  1FAK I;  1BF0 A;  1AAL A;  5JB4 A;  2HEX A;  1ZJD B;  5PTI A;  1KIG I;  1T8O B;  2ZVX A;  1P2J I;  1TAW B;  4BD9 B;  3BTW I;  3CI7 A;  5JB5 A;  1Y62 A;  3FP7 J;  2DDJ A;  4Y0Z I;  1T7C B;  3TPI I;  1EJM B;  1YC0 I;  2LFL A;  3GYM I;  1PIT A;  6PTI A;  3BTG I;  2KNT A;  1P2Q B;  1FAN A;  3OFW A;  3BTM I;  1BHC A;  2FTM B;  1DTK A;  1YLC B;  4WXV C;  2UUY B;  3P92 E;  1BTH P;  1P2K I;  3BYB A;  3UIR C;  1BUN B;  3BTQ I;  1BTI A;  1LD5 A;  2FI3 I;  9PTI A;  1D0D B;  1LD6 A;  1F5R I;  3AUD A;  2W8X A;  1CA0 D;  1BRC I;  2JOT A;  4DG4 C;  2FI5 I;  2IJO I;  3T62 D;  4WWY C;  3TGI I;  1D0D A;  3P95 E;  3BTH I;  1UUA A;  1UUB A;  3UOU B;  2M99 A;  3L3T E;  3BTD I;  3M7Q B;  3FP8 I;  1BZ5 A;  2R9P E; 
#chains in the Genus database with same CATH topology
 1DEM A;  4Y10 I;  1AAP A;  3AUG A;  4BQD A;  2FTL I;  3L33 E;  4NTY B;  5JB6 A;  1JV9 A;  3BTE I;  1YLD B;  4U30 W;  1OA6 5;  1BPI A;  3AUE A;  8PTI A;  2KCR A;  1SHP A;  4TPI I;  1T8M B;  4NTX B;  4ISO B;  4Y0Y I;  5C67 C;  3LDI A;  1T8L B;  1DEN A;  1T8N B;  3AUI A;  4DTG K;  1BRB I;  1CBW D;  1BPT A;  3AUB A;  1FY8 I;  1IRH A;  1MTN D;  1KUN A;  1ZR0 B;  2DDI A;  7PTI A;  1DTX A;  3U1J E;  4BNR I;  4U32 X;  2PTC I;  3LDM A;  1P2O B;  1P2N B;  2TPI I;  5JB7 A;  3OTJ I;  4ISN B;  2ODY E;  3AUH A;  2LFK A;  3BTT I;  4ISL B;  1QLQ A;  3BTK I;  1ADZ A;  3BTF I;  1P2M B;  1TCP A;  1G6X A;  1BIK A;  3WNY A;  1KTH A;  3TGJ I;  2J6D A;  2KAI I;  3LDJ A;  1BZX I;  2FI4 I;  1CO7 I;  1JC6 A;  2UUX A;  2CA7 A;  4NTW B;  1TOC R;  1K6U A;  3FP6 I;  1B0C A;  1KNT A;  1TFX C;  2M01 A;  1OA5 5;  2ZJX A;  2TGP I;  1TPA I;  1YKT B;  3D65 I;  4Y11 I;  1JV8 A;  1F7Z I;  3TGK I;  1P2I I;  1EAW B;  1NAG A;  3AUC A;  4PTI A;  1TAP A;  2RA3 C;  1FAK I;  1BF0 A;  1AAL A;  5JB4 A;  2HEX A;  1ZJD B;  5PTI A;  1KIG I;  1T8O B;  2ZVX A;  1P2J I;  1TAW B;  4BD9 B;  3BTW I;  3CI7 A;  5JB5 A;  1Y62 A;  3FP7 J;  2DDJ A;  4Y0Z I;  1T7C B;  3TPI I;  1EJM B;  1YC0 I;  2LFL A;  3GYM I;  1PIT A;  6PTI A;  3BTG I;  2KNT A;  1P2Q B;  1FAN A;  3OFW A;  3BTM I;  1BHC A;  2FTM B;  1DTK A;  1YLC B;  4WXV C;  2UUY B;  3P92 E;  1BTH P;  1P2K I;  3BYB A;  3UIR C;  1BUN B;  3BTQ I;  1BTI A;  1LD5 A;  2FI3 I;  9PTI A;  1D0D B;  1LD6 A;  1F5R I;  3AUD A;  2W8X A;  1CA0 D;  1BRC I;  2JOT A;  4DG4 C;  2FI5 I;  2IJO I;  3T62 D;  4WWY C;  3TGI I;  1D0D A;  3P95 E;  3BTH I;  1UUA A;  1UUB A;  3UOU B;  2M99 A;  3L3T E;  3BTD I;  3M7Q B;  3FP8 I;  1BZ5 A;  2R9P E; 
#chains in the Genus database with same CATH homology
 1DEM A;  4Y10 I;  1AAP A;  3AUG A;  4BQD A;  2FTL I;  3L33 E;  4NTY B;  5JB6 A;  1JV9 A;  3BTE I;  1YLD B;  4U30 W;  1OA6 5;  1BPI A;  3AUE A;  8PTI A;  2KCR A;  1SHP A;  4TPI I;  1T8M B;  4NTX B;  4ISO B;  4Y0Y I;  5C67 C;  3LDI A;  1T8L B;  1DEN A;  1T8N B;  3AUI A;  4DTG K;  1BRB I;  1CBW D;  1BPT A;  3AUB A;  1FY8 I;  1IRH A;  1MTN D;  1KUN A;  1ZR0 B;  2DDI A;  7PTI A;  1DTX A;  3U1J E;  4BNR I;  4U32 X;  2PTC I;  3LDM A;  1P2O B;  1P2N B;  2TPI I;  5JB7 A;  3OTJ I;  4ISN B;  2ODY E;  3AUH A;  2LFK A;  3BTT I;  4ISL B;  1QLQ A;  3BTK I;  1ADZ A;  3BTF I;  1P2M B;  1TCP A;  1G6X A;  1BIK A;  3WNY A;  1KTH A;  3TGJ I;  2J6D A;  2KAI I;  3LDJ A;  1BZX I;  2FI4 I;  1CO7 I;  1JC6 A;  2UUX A;  2CA7 A;  4NTW B;  1TOC R;  1K6U A;  3FP6 I;  1B0C A;  1KNT A;  1TFX C;  2M01 A;  1OA5 5;  2ZJX A;  2TGP I;  1TPA I;  1YKT B;  3D65 I;  4Y11 I;  1JV8 A;  1F7Z I;  3TGK I;  1P2I I;  1EAW B;  1NAG A;  3AUC A;  4PTI A;  1TAP A;  2RA3 C;  1FAK I;  1BF0 A;  1AAL A;  5JB4 A;  2HEX A;  1ZJD B;  5PTI A;  1KIG I;  1T8O B;  2ZVX A;  1P2J I;  1TAW B;  4BD9 B;  3BTW I;  3CI7 A;  5JB5 A;  1Y62 A;  3FP7 J;  2DDJ A;  4Y0Z I;  1T7C B;  3TPI I;  1EJM B;  1YC0 I;  2LFL A;  3GYM I;  1PIT A;  6PTI A;  3BTG I;  2KNT A;  1P2Q B;  1FAN A;  3OFW A;  3BTM I;  1BHC A;  2FTM B;  1DTK A;  1YLC B;  4WXV C;  2UUY B;  3P92 E;  1BTH P;  1P2K I;  3BYB A;  3UIR C;  1BUN B;  3BTQ I;  1BTI A;  1LD5 A;  2FI3 I;  9PTI A;  1D0D B;  1LD6 A;  1F5R I;  3AUD A;  2W8X A;  1CA0 D;  1BRC I;  2JOT A;  4DG4 C;  2FI5 I;  2IJO I;  3T62 D;  4WWY C;  3TGI I;  1D0D A;  3P95 E;  3BTH I;  1UUA A;  1UUB A;  3UOU B;  2M99 A;  3L3T E;  3BTD I;  3M7Q B;  3FP8 I;  1BZ5 A;  2R9P E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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