1T8NB

Crystal structure of the p1 thr bpti mutant- bovine chymotrypsin complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCTARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords Chymotrypsin A
total genus 11
structure length 58
sequence length 58
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1t8nB00
5JB6A 1LD6A 1FAKI 1B0CA 3LDIA 1AALA 1SHPA 1TCPA 1F5RI 1YLCB 3U1JE 3LDJA 2TPII 5JB4A 4Y0ZI 2DDJA 2LFKA 3AUIA 5C67C 1YLDB 1DENA 2FI3I 1P2NB 3BTQI 3OFWA 4WXVC 1BF0A 1KNTA 4Y10I 2RA3C 4NTXB 2HEXA 1AAPA 3AUCA 1CBWD 3D65I 1EAWB 4NTWB 1BUNB 1TAPA 3L33E 2J6DA 3P92E 7PTIA 1D0DA 8PTIA 3BTKI 4Y0YI 1ADZA 3BTWI 2UUXA 1D0DB 3BTFI 3BYBA 4DTGK 2KNTA 3FP7J 4NTYB 1F7ZI 2CA7A 3CI7A 1T7CB 3T62D 6PTIA 1TFXC 4WWYC 2M99A 3UIRC 4U30W 2DDIA 1KTHA 1P2JI 1P2KI 1MTND 1YKTB 3WNYA 1DTKA 4PTIA 3BTDI 1NAGA 3BTMI 1T8MB 3BTHI 3AUEA 1YC0I 1KUNA 1CO7I 2FTMB 4TPII 3BTGI 4ISLB 3TPII 2ZVXA 1KIGI 2FTLI 3OTJI 3TGJI 3BTTI 3FP6I 2KCRA 1JC6A 1G6XA 2KAII 1BZXI 1DTXA 1P2QB 1DEMA 1BPTA 4U32X 3BTEI 2ZJXA 1ZJDB 4BD9B 2JOTA 1K6UA 1Y62A 9PTIA 3M7QB 5JB5A 1BTIA 3AUDA 2UUYB 3AUBA 1T8LB 3FP8I 3UOUB 4BNRI 1EJMB 1P2OB 2LFLA 4ISOB 3GYMI 2FI5I 1IRHA 5JB7A 4DG4C 1BPIA 1CA0D 3L3TE 2TGPI 1BTHP 1BHCA 5PTIA 4ISNB 3LDMA 1JV8A 1BRBI 2ODYE 2R9PE 1OA55 2FI4I 3P95E 1OA65 1ZR0B 2IJOI 1T8OB 1TAWB 4BQDA 1UUAA 1TOCR 2M01A 1P2MB 1TPAI 3AUHA 3TGKI 1LD5A 1P2II 2PTCI 1T8NB 4Y11I 1FY8I 1BRCI 1JV9A 1BZ5A 2W8XA 1PITA 1BIKA 3AUGA 3TGII 1FANA 1QLQA 1UUBA
chains in the Genus database with same CATH superfamily
5JB6A 1LD6A 1FAKI 1B0CA 3LDIA 1AALA 1SHPA 1TCPA 1F5RI 1YLCB 3U1JE 3LDJA 2TPII 5JB4A 4Y0ZI 2DDJA 2LFKA 3AUIA 5C67C 1YLDB 1DENA 2FI3I 1P2NB 3BTQI 3OFWA 4WXVC 1BF0A 1KNTA 4Y10I 2RA3C 4NTXB 2HEXA 1AAPA 3AUCA 1CBWD 3D65I 1EAWB 4NTWB 1BUNB 1TAPA 3L33E 2J6DA 3P92E 7PTIA 1D0DA 8PTIA 3BTKI 4Y0YI 1ADZA 3BTWI 2UUXA 1D0DB 3BTFI 3BYBA 4DTGK 2KNTA 3FP7J 4NTYB 1F7ZI 2CA7A 3CI7A 1T7CB 3T62D 6PTIA 1TFXC 4WWYC 2M99A 3UIRC 4U30W 2DDIA 1KTHA 1P2JI 1P2KI 1MTND 1YKTB 3WNYA 1DTKA 4PTIA 3BTDI 1NAGA 3BTMI 1T8MB 3BTHI 3AUEA 1YC0I 1KUNA 1CO7I 2FTMB 4TPII 3BTGI 4ISLB 3TPII 2ZVXA 1KIGI 2FTLI 3OTJI 3TGJI 3BTTI 3FP6I 2KCRA 1JC6A 1G6XA 2KAII 1BZXI 1DTXA 1P2QB 1DEMA 1BPTA 4U32X 3BTEI 2ZJXA 1ZJDB 4BD9B 2JOTA 1K6UA 1Y62A 9PTIA 3M7QB 5JB5A 1BTIA 3AUDA 2UUYB 3AUBA 1T8LB 3FP8I 3UOUB 4BNRI 1EJMB 1P2OB 2LFLA 4ISOB 3GYMI 2FI5I 1IRHA 5JB7A 4DG4C 1BPIA 1CA0D 3L3TE 2TGPI 1BTHP 1BHCA 5PTIA 4ISNB 3LDMA 1JV8A 1BRBI 2ODYE 2R9PE 1OA55 2FI4I 3P95E 1OA65 1ZR0B 2IJOI 1T8OB 1TAWB 4BQDA 1UUAA 1TOCR 2M01A 1P2MB 1TPAI 3AUHA 3TGKI 1LD5A 1P2II 2PTCI 1T8NB 4Y11I 1FY8I 1BRCI 1JV9A 1BZ5A 2W8XA 1PITA 1BIKA 3AUGA 3TGII 1FANA 1QLQA 1UUBA
chains in the Genus database with same CATH topology
5JB6A 1LD6A 1FAKI 1B0CA 3LDIA 1AALA 1SHPA 1TCPA 1F5RI 1YLCB 3U1JE 3LDJA 2TPII 5JB4A 4Y0ZI 2DDJA 2LFKA 3AUIA 5C67C 1YLDB 1DENA 2FI3I 1P2NB 3BTQI 3OFWA 4WXVC 1BF0A 1KNTA 4Y10I 2RA3C 4NTXB 2HEXA 1AAPA 3AUCA 1CBWD 3D65I 1EAWB 4NTWB 1BUNB 1TAPA 3L33E 2J6DA 3P92E 7PTIA 1D0DA 8PTIA 3BTKI 4Y0YI 1ADZA 3BTWI 2UUXA 1D0DB 3BTFI 3BYBA 4DTGK 2KNTA 3FP7J 4NTYB 1F7ZI 2CA7A 3CI7A 1T7CB 3T62D 6PTIA 1TFXC 4WWYC 2M99A 3UIRC 4U30W 2DDIA 1KTHA 1P2JI 1P2KI 1MTND 1YKTB 3WNYA 1DTKA 4PTIA 3BTDI 1NAGA 3BTMI 1T8MB 3BTHI 3AUEA 1YC0I 1KUNA 1CO7I 2FTMB 4TPII 3BTGI 4ISLB 3TPII 2ZVXA 1KIGI 2FTLI 3OTJI 3TGJI 3BTTI 3FP6I 2KCRA 1JC6A 1G6XA 2KAII 1BZXI 1DTXA 1P2QB 1DEMA 1BPTA 4U32X 3BTEI 2ZJXA 1ZJDB 4BD9B 2JOTA 1K6UA 1Y62A 9PTIA 3M7QB 5JB5A 1BTIA 3AUDA 2UUYB 3AUBA 1T8LB 3FP8I 3UOUB 4BNRI 1EJMB 1P2OB 2LFLA 4ISOB 3GYMI 2FI5I 1IRHA 5JB7A 4DG4C 1BPIA 1CA0D 3L3TE 2TGPI 1BTHP 1BHCA 5PTIA 4ISNB 3LDMA 1JV8A 1BRBI 2ODYE 2R9PE 1OA55 2FI4I 3P95E 1OA65 1ZR0B 2IJOI 1T8OB 1TAWB 4BQDA 1UUAA 1TOCR 2M01A 1P2MB 1TPAI 3AUHA 3TGKI 1LD5A 1P2II 2PTCI 1T8NB 4Y11I 1FY8I 1BRCI 1JV9A 1BZ5A 2W8XA 1PITA 1BIKA 3AUGA 3TGII 1FANA 1QLQA 1UUBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JB6 A;  1LD6 A;  1FAK I;  1B0C A;  3LDI A;  1AAL A;  1SHP A;  1TCP A;  1F5R I;  1YLC B;  3U1J E;  3LDJ A;  2TPI I;  5JB4 A;  4Y0Z I;  2DDJ A;  2LFK A;  3AUI A;  5C67 C;  1YLD B;  1DEN A;  2FI3 I;  1P2N B;  3BTQ I;  3OFW A;  4WXV C;  1BF0 A;  1KNT A;  4Y10 I;  2RA3 C;  4NTX B;  2HEX A;  1AAP A;  3AUC A;  1CBW D;  3D65 I;  1EAW B;  4NTW B;  1BUN B;  1TAP A;  3L33 E;  2J6D A;  3P92 E;  7PTI A;  1D0D A;  8PTI A;  3BTK I;  4Y0Y I;  1ADZ A;  3BTW I;  2UUX A;  1D0D B;  3BTF I;  3BYB A;  4DTG K;  2KNT A;  3FP7 J;  4NTY B;  1F7Z I;  2CA7 A;  3CI7 A;  1T7C B;  3T62 D;  6PTI A;  1TFX C;  4WWY C;  2M99 A;  3UIR C;  4U30 W;  2DDI A;  1KTH A;  1P2J I;  1P2K I;  1MTN D;  1YKT B;  3WNY A;  1DTK A;  4PTI A;  3BTD I;  1NAG A;  3BTM I;  1T8M B;  3BTH I;  3AUE A;  1YC0 I;  1KUN A;  1CO7 I;  2FTM B;  4TPI I;  3BTG I;  4ISL B;  3TPI I;  2ZVX A;  1KIG I;  2FTL I;  3OTJ I;  3TGJ I;  3BTT I;  3FP6 I;  2KCR A;  1JC6 A;  1G6X A;  2KAI I;  1BZX I;  1DTX A;  1P2Q B;  1DEM A;  1BPT A;  4U32 X;  3BTE I;  2ZJX A;  1ZJD B;  4BD9 B;  2JOT A;  1K6U A;  1Y62 A;  9PTI A;  3M7Q B;  5JB5 A;  1BTI A;  3AUD A;  2UUY B;  3AUB A;  1T8L B;  3FP8 I;  3UOU B;  4BNR I;  1EJM B;  1P2O B;  2LFL A;  4ISO B;  3GYM I;  2FI5 I;  1IRH A;  5JB7 A;  4DG4 C;  1BPI A;  1CA0 D;  3L3T E;  2TGP I;  1BTH P;  1BHC A;  5PTI A;  4ISN B;  3LDM A;  1JV8 A;  1BRB I;  2ODY E;  2R9P E;  1OA5 5;  2FI4 I;  3P95 E;  1OA6 5;  1ZR0 B;  2IJO I;  1T8O B;  1TAW B;  4BQD A;  1UUA A;  1TOC R;  2M01 A;  1P2M B;  1TPA I;  3AUH A;  3TGK I;  1LD5 A;  1P2I I;  2PTC I;  1T8N B;  4Y11 I;  1FY8 I;  1BRC I;  1JV9 A;  1BZ5 A;  2W8X A;  1PIT A;  1BIK A;  3AUG A;  3TGI I;  1FAN A;  1QLQ A;  1UUB A; 
#chains in the Genus database with same CATH topology
 5JB6 A;  1LD6 A;  1FAK I;  1B0C A;  3LDI A;  1AAL A;  1SHP A;  1TCP A;  1F5R I;  1YLC B;  3U1J E;  3LDJ A;  2TPI I;  5JB4 A;  4Y0Z I;  2DDJ A;  2LFK A;  3AUI A;  5C67 C;  1YLD B;  1DEN A;  2FI3 I;  1P2N B;  3BTQ I;  3OFW A;  4WXV C;  1BF0 A;  1KNT A;  4Y10 I;  2RA3 C;  4NTX B;  2HEX A;  1AAP A;  3AUC A;  1CBW D;  3D65 I;  1EAW B;  4NTW B;  1BUN B;  1TAP A;  3L33 E;  2J6D A;  3P92 E;  7PTI A;  1D0D A;  8PTI A;  3BTK I;  4Y0Y I;  1ADZ A;  3BTW I;  2UUX A;  1D0D B;  3BTF I;  3BYB A;  4DTG K;  2KNT A;  3FP7 J;  4NTY B;  1F7Z I;  2CA7 A;  3CI7 A;  1T7C B;  3T62 D;  6PTI A;  1TFX C;  4WWY C;  2M99 A;  3UIR C;  4U30 W;  2DDI A;  1KTH A;  1P2J I;  1P2K I;  1MTN D;  1YKT B;  3WNY A;  1DTK A;  4PTI A;  3BTD I;  1NAG A;  3BTM I;  1T8M B;  3BTH I;  3AUE A;  1YC0 I;  1KUN A;  1CO7 I;  2FTM B;  4TPI I;  3BTG I;  4ISL B;  3TPI I;  2ZVX A;  1KIG I;  2FTL I;  3OTJ I;  3TGJ I;  3BTT I;  3FP6 I;  2KCR A;  1JC6 A;  1G6X A;  2KAI I;  1BZX I;  1DTX A;  1P2Q B;  1DEM A;  1BPT A;  4U32 X;  3BTE I;  2ZJX A;  1ZJD B;  4BD9 B;  2JOT A;  1K6U A;  1Y62 A;  9PTI A;  3M7Q B;  5JB5 A;  1BTI A;  3AUD A;  2UUY B;  3AUB A;  1T8L B;  3FP8 I;  3UOU B;  4BNR I;  1EJM B;  1P2O B;  2LFL A;  4ISO B;  3GYM I;  2FI5 I;  1IRH A;  5JB7 A;  4DG4 C;  1BPI A;  1CA0 D;  3L3T E;  2TGP I;  1BTH P;  1BHC A;  5PTI A;  4ISN B;  3LDM A;  1JV8 A;  1BRB I;  2ODY E;  2R9P E;  1OA5 5;  2FI4 I;  3P95 E;  1OA6 5;  1ZR0 B;  2IJO I;  1T8O B;  1TAW B;  4BQD A;  1UUA A;  1TOC R;  2M01 A;  1P2M B;  1TPA I;  3AUH A;  3TGK I;  1LD5 A;  1P2I I;  2PTC I;  1T8N B;  4Y11 I;  1FY8 I;  1BRC I;  1JV9 A;  1BZ5 A;  2W8X A;  1PIT A;  1BIK A;  3AUG A;  3TGI I;  1FAN A;  1QLQ A;  1UUB A; 
#chains in the Genus database with same CATH homology
 5JB6 A;  1LD6 A;  1FAK I;  1B0C A;  3LDI A;  1AAL A;  1SHP A;  1TCP A;  1F5R I;  1YLC B;  3U1J E;  3LDJ A;  2TPI I;  5JB4 A;  4Y0Z I;  2DDJ A;  2LFK A;  3AUI A;  5C67 C;  1YLD B;  1DEN A;  2FI3 I;  1P2N B;  3BTQ I;  3OFW A;  4WXV C;  1BF0 A;  1KNT A;  4Y10 I;  2RA3 C;  4NTX B;  2HEX A;  1AAP A;  3AUC A;  1CBW D;  3D65 I;  1EAW B;  4NTW B;  1BUN B;  1TAP A;  3L33 E;  2J6D A;  3P92 E;  7PTI A;  1D0D A;  8PTI A;  3BTK I;  4Y0Y I;  1ADZ A;  3BTW I;  2UUX A;  1D0D B;  3BTF I;  3BYB A;  4DTG K;  2KNT A;  3FP7 J;  4NTY B;  1F7Z I;  2CA7 A;  3CI7 A;  1T7C B;  3T62 D;  6PTI A;  1TFX C;  4WWY C;  2M99 A;  3UIR C;  4U30 W;  2DDI A;  1KTH A;  1P2J I;  1P2K I;  1MTN D;  1YKT B;  3WNY A;  1DTK A;  4PTI A;  3BTD I;  1NAG A;  3BTM I;  1T8M B;  3BTH I;  3AUE A;  1YC0 I;  1KUN A;  1CO7 I;  2FTM B;  4TPI I;  3BTG I;  4ISL B;  3TPI I;  2ZVX A;  1KIG I;  2FTL I;  3OTJ I;  3TGJ I;  3BTT I;  3FP6 I;  2KCR A;  1JC6 A;  1G6X A;  2KAI I;  1BZX I;  1DTX A;  1P2Q B;  1DEM A;  1BPT A;  4U32 X;  3BTE I;  2ZJX A;  1ZJD B;  4BD9 B;  2JOT A;  1K6U A;  1Y62 A;  9PTI A;  3M7Q B;  5JB5 A;  1BTI A;  3AUD A;  2UUY B;  3AUB A;  1T8L B;  3FP8 I;  3UOU B;  4BNR I;  1EJM B;  1P2O B;  2LFL A;  4ISO B;  3GYM I;  2FI5 I;  1IRH A;  5JB7 A;  4DG4 C;  1BPI A;  1CA0 D;  3L3T E;  2TGP I;  1BTH P;  1BHC A;  5PTI A;  4ISN B;  3LDM A;  1JV8 A;  1BRB I;  2ODY E;  2R9P E;  1OA5 5;  2FI4 I;  3P95 E;  1OA6 5;  1ZR0 B;  2IJO I;  1T8O B;  1TAW B;  4BQD A;  1UUA A;  1TOC R;  2M01 A;  1P2M B;  1TPA I;  3AUH A;  3TGK I;  1LD5 A;  1P2I I;  2PTC I;  1T8N B;  4Y11 I;  1FY8 I;  1BRC I;  1JV9 A;  1BZ5 A;  2W8X A;  1PIT A;  1BIK A;  3AUG A;  3TGI I;  1FAN A;  1QLQ A;  1UUB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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