1T8OB

Crystal structure of the p1 trp bpti mutant- bovine chymotrypsin complex
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCWARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCLRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords Chymotrypsin A
total genus 11
structure length 58
sequence length 58
chains with identical sequence D
ec nomenclature
pdb deposition date 2004-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 1t8oB00
1KUNA 4WWYC 3AUDA 4ISLB 5JB6A 1F5RI 2LFLA 3GYMI 4DG4C 2FI3I 6PTIA 3TGJI 5PTIA 3BTHI 3TGKI 1BHCA 1YLDB 1P2II 2HEXA 3LDIA 4Y10I 3BYBA 1BTHP 4Y11I 2DDIA 1BRBI 1DTXA 1P2NB 2LFKA 2KAII 1D0DA 4Y0YI 1ZJDB 1KNTA 1NAGA 3P95E 4TPII 4Y0ZI 2UUXA 1YKTB 4ISNB 1ADZA 1LD5A 1F7ZI 1T8OB 4PTIA 8PTIA 3AUEA 1P2KI 1FANA 2ZVXA 1BF0A 1BIKA 1TOCR 1BPIA 3TGII 1MTND 1IRHA 1G6XA 3AUHA 3D65I 4BQDA 1ZR0B 2KNTA 4U30W 4NTYB 1UUBA 1P2OB 3BTWI 1CA0D 1BZXI 1SHPA 3BTDI 1LD6A 1TPAI 1JV8A 1T8NB 2CA7A 3U1JE 1TAPA 1QLQA 3BTKI 1KIGI 3CI7A 1T8LB 3AUIA 3BTTI 1P2JI 2PTCI 1BRCI 1YC0I 1T7CB 3TPII 1FAKI 4BD9B 5JB4A 4U32X 7PTIA 3BTQI 3L3TE 1PITA 2ODYE 1AALA 3AUBA 1JV9A 3L33E 2ZJXA 1P2MB 1DTKA 1TAWB 1BPTA 2J6DA 4BNRI 3T62D 1AAPA 1JC6A 2UUYB 1B0CA 9PTIA 1UUAA 1DENA 1BTIA 2M99A 3LDJA 3WNYA 1KTHA 2FTLI 1EJMB 3UIRC 2FTMB 1D0DB 2DDJA 1P2QB 3FP7J 1CO7I 3BTEI 2TGPI 1BUNB 4WXVC 5C67C 1OA65 5JB7A 2KCRA 2JOTA 4ISOB 3OFWA 2FI5I 2FI4I 1DEMA 3M7QB 1Y62A 2R9PE 3FP6I 3UOUB 1K6UA 2IJOI 3P92E 3BTMI 2M01A 4NTWB 1FY8I 3LDMA 4DTGK 3FP8I 1OA55 3BTFI 2W8XA 3AUGA 5JB5A 4NTXB 1YLCB 2RA3C 1TFXC 2TPII 3AUCA 1CBWD 1BZ5A 3OTJI 3BTGI 1T8MB 1EAWB 1TCPA
chains in the Genus database with same CATH superfamily
1KUNA 4WWYC 3AUDA 4ISLB 5JB6A 1F5RI 2LFLA 3GYMI 4DG4C 2FI3I 6PTIA 3TGJI 5PTIA 3BTHI 3TGKI 1BHCA 1YLDB 1P2II 2HEXA 3LDIA 4Y10I 3BYBA 1BTHP 4Y11I 2DDIA 1BRBI 1DTXA 1P2NB 2LFKA 2KAII 1D0DA 4Y0YI 1ZJDB 1KNTA 1NAGA 3P95E 4TPII 4Y0ZI 2UUXA 1YKTB 4ISNB 1ADZA 1LD5A 1F7ZI 1T8OB 4PTIA 8PTIA 3AUEA 1P2KI 1FANA 2ZVXA 1BF0A 1BIKA 1TOCR 1BPIA 3TGII 1MTND 1IRHA 1G6XA 3AUHA 3D65I 4BQDA 1ZR0B 2KNTA 4U30W 4NTYB 1UUBA 1P2OB 3BTWI 1CA0D 1BZXI 1SHPA 3BTDI 1LD6A 1TPAI 1JV8A 1T8NB 2CA7A 3U1JE 1TAPA 1QLQA 3BTKI 1KIGI 3CI7A 1T8LB 3AUIA 3BTTI 1P2JI 2PTCI 1BRCI 1YC0I 1T7CB 3TPII 1FAKI 4BD9B 5JB4A 4U32X 7PTIA 3BTQI 3L3TE 1PITA 2ODYE 1AALA 3AUBA 1JV9A 3L33E 2ZJXA 1P2MB 1DTKA 1TAWB 1BPTA 2J6DA 4BNRI 3T62D 1AAPA 1JC6A 2UUYB 1B0CA 9PTIA 1UUAA 1DENA 1BTIA 2M99A 3LDJA 3WNYA 1KTHA 2FTLI 1EJMB 3UIRC 2FTMB 1D0DB 2DDJA 1P2QB 3FP7J 1CO7I 3BTEI 2TGPI 1BUNB 4WXVC 5C67C 1OA65 5JB7A 2KCRA 2JOTA 4ISOB 3OFWA 2FI5I 2FI4I 1DEMA 3M7QB 1Y62A 2R9PE 3FP6I 3UOUB 1K6UA 2IJOI 3P92E 3BTMI 2M01A 4NTWB 1FY8I 3LDMA 4DTGK 3FP8I 1OA55 3BTFI 2W8XA 3AUGA 5JB5A 4NTXB 1YLCB 2RA3C 1TFXC 2TPII 3AUCA 1CBWD 1BZ5A 3OTJI 3BTGI 1T8MB 1EAWB 1TCPA
chains in the Genus database with same CATH topology
1KUNA 4WWYC 3AUDA 4ISLB 5JB6A 1F5RI 2LFLA 3GYMI 4DG4C 2FI3I 6PTIA 3TGJI 5PTIA 3BTHI 3TGKI 1BHCA 1YLDB 1P2II 2HEXA 3LDIA 4Y10I 3BYBA 1BTHP 4Y11I 2DDIA 1BRBI 1DTXA 1P2NB 2LFKA 2KAII 1D0DA 4Y0YI 1ZJDB 1KNTA 1NAGA 3P95E 4TPII 4Y0ZI 2UUXA 1YKTB 4ISNB 1ADZA 1LD5A 1F7ZI 1T8OB 4PTIA 8PTIA 3AUEA 1P2KI 1FANA 2ZVXA 1BF0A 1BIKA 1TOCR 1BPIA 3TGII 1MTND 1IRHA 1G6XA 3AUHA 3D65I 4BQDA 1ZR0B 2KNTA 4U30W 4NTYB 1UUBA 1P2OB 3BTWI 1CA0D 1BZXI 1SHPA 3BTDI 1LD6A 1TPAI 1JV8A 1T8NB 2CA7A 3U1JE 1TAPA 1QLQA 3BTKI 1KIGI 3CI7A 1T8LB 3AUIA 3BTTI 1P2JI 2PTCI 1BRCI 1YC0I 1T7CB 3TPII 1FAKI 4BD9B 5JB4A 4U32X 7PTIA 3BTQI 3L3TE 1PITA 2ODYE 1AALA 3AUBA 1JV9A 3L33E 2ZJXA 1P2MB 1DTKA 1TAWB 1BPTA 2J6DA 4BNRI 3T62D 1AAPA 1JC6A 2UUYB 1B0CA 9PTIA 1UUAA 1DENA 1BTIA 2M99A 3LDJA 3WNYA 1KTHA 2FTLI 1EJMB 3UIRC 2FTMB 1D0DB 2DDJA 1P2QB 3FP7J 1CO7I 3BTEI 2TGPI 1BUNB 4WXVC 5C67C 1OA65 5JB7A 2KCRA 2JOTA 4ISOB 3OFWA 2FI5I 2FI4I 1DEMA 3M7QB 1Y62A 2R9PE 3FP6I 3UOUB 1K6UA 2IJOI 3P92E 3BTMI 2M01A 4NTWB 1FY8I 3LDMA 4DTGK 3FP8I 1OA55 3BTFI 2W8XA 3AUGA 5JB5A 4NTXB 1YLCB 2RA3C 1TFXC 2TPII 3AUCA 1CBWD 1BZ5A 3OTJI 3BTGI 1T8MB 1EAWB 1TCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KUN A;  4WWY C;  3AUD A;  4ISL B;  5JB6 A;  1F5R I;  2LFL A;  3GYM I;  4DG4 C;  2FI3 I;  6PTI A;  3TGJ I;  5PTI A;  3BTH I;  3TGK I;  1BHC A;  1YLD B;  1P2I I;  2HEX A;  3LDI A;  4Y10 I;  3BYB A;  1BTH P;  4Y11 I;  2DDI A;  1BRB I;  1DTX A;  1P2N B;  2LFK A;  2KAI I;  1D0D A;  4Y0Y I;  1ZJD B;  1KNT A;  1NAG A;  3P95 E;  4TPI I;  4Y0Z I;  2UUX A;  1YKT B;  4ISN B;  1ADZ A;  1LD5 A;  1F7Z I;  1T8O B;  4PTI A;  8PTI A;  3AUE A;  1P2K I;  1FAN A;  2ZVX A;  1BF0 A;  1BIK A;  1TOC R;  1BPI A;  3TGI I;  1MTN D;  1IRH A;  1G6X A;  3AUH A;  3D65 I;  4BQD A;  1ZR0 B;  2KNT A;  4U30 W;  4NTY B;  1UUB A;  1P2O B;  3BTW I;  1CA0 D;  1BZX I;  1SHP A;  3BTD I;  1LD6 A;  1TPA I;  1JV8 A;  1T8N B;  2CA7 A;  3U1J E;  1TAP A;  1QLQ A;  3BTK I;  1KIG I;  3CI7 A;  1T8L B;  3AUI A;  3BTT I;  1P2J I;  2PTC I;  1BRC I;  1YC0 I;  1T7C B;  3TPI I;  1FAK I;  4BD9 B;  5JB4 A;  4U32 X;  7PTI A;  3BTQ I;  3L3T E;  1PIT A;  2ODY E;  1AAL A;  3AUB A;  1JV9 A;  3L33 E;  2ZJX A;  1P2M B;  1DTK A;  1TAW B;  1BPT A;  2J6D A;  4BNR I;  3T62 D;  1AAP A;  1JC6 A;  2UUY B;  1B0C A;  9PTI A;  1UUA A;  1DEN A;  1BTI A;  2M99 A;  3LDJ A;  3WNY A;  1KTH A;  2FTL I;  1EJM B;  3UIR C;  2FTM B;  1D0D B;  2DDJ A;  1P2Q B;  3FP7 J;  1CO7 I;  3BTE I;  2TGP I;  1BUN B;  4WXV C;  5C67 C;  1OA6 5;  5JB7 A;  2KCR A;  2JOT A;  4ISO B;  3OFW A;  2FI5 I;  2FI4 I;  1DEM A;  3M7Q B;  1Y62 A;  2R9P E;  3FP6 I;  3UOU B;  1K6U A;  2IJO I;  3P92 E;  3BTM I;  2M01 A;  4NTW B;  1FY8 I;  3LDM A;  4DTG K;  3FP8 I;  1OA5 5;  3BTF I;  2W8X A;  3AUG A;  5JB5 A;  4NTX B;  1YLC B;  2RA3 C;  1TFX C;  2TPI I;  3AUC A;  1CBW D;  1BZ5 A;  3OTJ I;  3BTG I;  1T8M B;  1EAW B;  1TCP A; 
#chains in the Genus database with same CATH topology
 1KUN A;  4WWY C;  3AUD A;  4ISL B;  5JB6 A;  1F5R I;  2LFL A;  3GYM I;  4DG4 C;  2FI3 I;  6PTI A;  3TGJ I;  5PTI A;  3BTH I;  3TGK I;  1BHC A;  1YLD B;  1P2I I;  2HEX A;  3LDI A;  4Y10 I;  3BYB A;  1BTH P;  4Y11 I;  2DDI A;  1BRB I;  1DTX A;  1P2N B;  2LFK A;  2KAI I;  1D0D A;  4Y0Y I;  1ZJD B;  1KNT A;  1NAG A;  3P95 E;  4TPI I;  4Y0Z I;  2UUX A;  1YKT B;  4ISN B;  1ADZ A;  1LD5 A;  1F7Z I;  1T8O B;  4PTI A;  8PTI A;  3AUE A;  1P2K I;  1FAN A;  2ZVX A;  1BF0 A;  1BIK A;  1TOC R;  1BPI A;  3TGI I;  1MTN D;  1IRH A;  1G6X A;  3AUH A;  3D65 I;  4BQD A;  1ZR0 B;  2KNT A;  4U30 W;  4NTY B;  1UUB A;  1P2O B;  3BTW I;  1CA0 D;  1BZX I;  1SHP A;  3BTD I;  1LD6 A;  1TPA I;  1JV8 A;  1T8N B;  2CA7 A;  3U1J E;  1TAP A;  1QLQ A;  3BTK I;  1KIG I;  3CI7 A;  1T8L B;  3AUI A;  3BTT I;  1P2J I;  2PTC I;  1BRC I;  1YC0 I;  1T7C B;  3TPI I;  1FAK I;  4BD9 B;  5JB4 A;  4U32 X;  7PTI A;  3BTQ I;  3L3T E;  1PIT A;  2ODY E;  1AAL A;  3AUB A;  1JV9 A;  3L33 E;  2ZJX A;  1P2M B;  1DTK A;  1TAW B;  1BPT A;  2J6D A;  4BNR I;  3T62 D;  1AAP A;  1JC6 A;  2UUY B;  1B0C A;  9PTI A;  1UUA A;  1DEN A;  1BTI A;  2M99 A;  3LDJ A;  3WNY A;  1KTH A;  2FTL I;  1EJM B;  3UIR C;  2FTM B;  1D0D B;  2DDJ A;  1P2Q B;  3FP7 J;  1CO7 I;  3BTE I;  2TGP I;  1BUN B;  4WXV C;  5C67 C;  1OA6 5;  5JB7 A;  2KCR A;  2JOT A;  4ISO B;  3OFW A;  2FI5 I;  2FI4 I;  1DEM A;  3M7Q B;  1Y62 A;  2R9P E;  3FP6 I;  3UOU B;  1K6U A;  2IJO I;  3P92 E;  3BTM I;  2M01 A;  4NTW B;  1FY8 I;  3LDM A;  4DTG K;  3FP8 I;  1OA5 5;  3BTF I;  2W8X A;  3AUG A;  5JB5 A;  4NTX B;  1YLC B;  2RA3 C;  1TFX C;  2TPI I;  3AUC A;  1CBW D;  1BZ5 A;  3OTJ I;  3BTG I;  1T8M B;  1EAW B;  1TCP A; 
#chains in the Genus database with same CATH homology
 1KUN A;  4WWY C;  3AUD A;  4ISL B;  5JB6 A;  1F5R I;  2LFL A;  3GYM I;  4DG4 C;  2FI3 I;  6PTI A;  3TGJ I;  5PTI A;  3BTH I;  3TGK I;  1BHC A;  1YLD B;  1P2I I;  2HEX A;  3LDI A;  4Y10 I;  3BYB A;  1BTH P;  4Y11 I;  2DDI A;  1BRB I;  1DTX A;  1P2N B;  2LFK A;  2KAI I;  1D0D A;  4Y0Y I;  1ZJD B;  1KNT A;  1NAG A;  3P95 E;  4TPI I;  4Y0Z I;  2UUX A;  1YKT B;  4ISN B;  1ADZ A;  1LD5 A;  1F7Z I;  1T8O B;  4PTI A;  8PTI A;  3AUE A;  1P2K I;  1FAN A;  2ZVX A;  1BF0 A;  1BIK A;  1TOC R;  1BPI A;  3TGI I;  1MTN D;  1IRH A;  1G6X A;  3AUH A;  3D65 I;  4BQD A;  1ZR0 B;  2KNT A;  4U30 W;  4NTY B;  1UUB A;  1P2O B;  3BTW I;  1CA0 D;  1BZX I;  1SHP A;  3BTD I;  1LD6 A;  1TPA I;  1JV8 A;  1T8N B;  2CA7 A;  3U1J E;  1TAP A;  1QLQ A;  3BTK I;  1KIG I;  3CI7 A;  1T8L B;  3AUI A;  3BTT I;  1P2J I;  2PTC I;  1BRC I;  1YC0 I;  1T7C B;  3TPI I;  1FAK I;  4BD9 B;  5JB4 A;  4U32 X;  7PTI A;  3BTQ I;  3L3T E;  1PIT A;  2ODY E;  1AAL A;  3AUB A;  1JV9 A;  3L33 E;  2ZJX A;  1P2M B;  1DTK A;  1TAW B;  1BPT A;  2J6D A;  4BNR I;  3T62 D;  1AAP A;  1JC6 A;  2UUY B;  1B0C A;  9PTI A;  1UUA A;  1DEN A;  1BTI A;  2M99 A;  3LDJ A;  3WNY A;  1KTH A;  2FTL I;  1EJM B;  3UIR C;  2FTM B;  1D0D B;  2DDJ A;  1P2Q B;  3FP7 J;  1CO7 I;  3BTE I;  2TGP I;  1BUN B;  4WXV C;  5C67 C;  1OA6 5;  5JB7 A;  2KCR A;  2JOT A;  4ISO B;  3OFW A;  2FI5 I;  2FI4 I;  1DEM A;  3M7Q B;  1Y62 A;  2R9P E;  3FP6 I;  3UOU B;  1K6U A;  2IJO I;  3P92 E;  3BTM I;  2M01 A;  4NTW B;  1FY8 I;  3LDM A;  4DTG K;  3FP8 I;  1OA5 5;  3BTF I;  2W8X A;  3AUG A;  5JB5 A;  4NTX B;  1YLC B;  2RA3 C;  1TFX C;  2TPI I;  3AUC A;  1CBW D;  1BZ5 A;  3OTJ I;  3BTG I;  1T8M B;  1EAW B;  1TCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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