1U7BA

Crystal structure of hpcna bound to residues 331-350 of the flap endonuclease-1 (fen1)
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
255
structure length
251
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
pubmed doi rcsb
molecule tags Replication
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 59
structure length 251
sequence length 255
ec nomenclature
pdb deposition date 2004-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 1u7bA00
4YHRA 3IFVA 1RXZA 2HIIC 2OD8A 3V62B 1PLRA 5DAIA 4CS5A 4HK1A 5DA7A 5A6DA 3V61B 5IXAA 3FDSC 3F1WA 4RJFA 1VYJA 1RXMA 1IZ4A 2IZOC 4ZTDA 3U5ZF 2ZVVA 3P83A 2NTIB 3TBLA 5IY4A 1UL1A 1UD9A 2NTIA 1B8HA 3HSLX 5CFKA 5E0TA 1CZDA 1B77A 3GPMA 1AXCA 2ZVLA 1PLQA 1VYMA 1YYPA 5E0VA 2NTIC 3G65B 4D2GA 1IZ5A 2IO4B 3G65A 4L6PA 5AUJA 3AIXA 2AVTA 3A1JA 2Z0LA 2IO4A 1T6LA 3G65C 5HACA 1U76A 3A2FB 1GE8A 2ZVMA 1U7BA 3A1JC 3I2MX 2HIIA 3U60F 2AWAA 3P91A 2HIKB 3AIXB 4L60A 3GGRB 1DMLA 3AIZA 3A1JB 3LX1A 2IJXA 3WGWA 2HIKA 5JNED 3GGRA 2IX2B 3AIZC 3GPNA 3U61F 2HIIB 3V60B 1ISQA 2HIKC 3P87A 5IWDA 2IX2A 1RWZA 3VKXA 5E0UA 2ZVWA 3HI8A 3GGRC 5B7OA 4TR6A 2IZOB 1SXJF 2ZVKA 1W60A 2IX2C 5H0TA 3K4XA 3FDSD 3LX2A
chains in the Genus database with same CATH superfamily
4YHRA 3IFVA 1RXZA 2HIIC 2OD8A 3V62B 1PLRA 5DAIA 4CS5A 4HK1A 5DA7A 5A6DA 3V61B 5IXAA 3FDSC 3F1WA 4RJFA 1VYJA 1RXMA 1IZ4A 2IZOC 4ZTDA 3U5ZF 2ZVVA 3P83A 2NTIB 3TBLA 5IY4A 1UL1A 1UD9A 2NTIA 1B8HA 3HSLX 5CFKA 5E0TA 1CZDA 1B77A 3GPMA 1AXCA 2ZVLA 1PLQA 1VYMA 1YYPA 5E0VA 2NTIC 3G65B 4D2GA 1IZ5A 2IO4B 3G65A 4L6PA 5AUJA 3AIXA 2AVTA 3A1JA 2Z0LA 2IO4A 1T6LA 3G65C 5HACA 1U76A 3A2FB 1GE8A 2ZVMA 1U7BA 3A1JC 3I2MX 2HIIA 3U60F 2AWAA 3P91A 2HIKB 3AIXB 4L60A 3GGRB 1DMLA 3AIZA 3A1JB 3LX1A 2IJXA 3WGWA 2HIKA 5JNED 3GGRA 2IX2B 3AIZC 3GPNA 3U61F 2HIIB 3V60B 1ISQA 2HIKC 3P87A 5IWDA 2IX2A 1RWZA 3VKXA 5E0UA 2ZVWA 3HI8A 3GGRC 5B7OA 4TR6A 2IZOB 1SXJF 2ZVKA 1W60A 2IX2C 5H0TA 3K4XA 3FDSD 3LX2A
chains in the Genus database with same CATH topology
4YHRA 3IFVA 1RXZA 2HIIC 2OD8A 3V62B 1PLRA 5DAIA 4CS5A 4HK1A 5DA7A 5A6DA 3V61B 5IXAA 3FDSC 3F1WA 4RJFA 1VYJA 1RXMA 1IZ4A 2IZOC 4ZTDA 3U5ZF 2ZVVA 3P83A 2NTIB 3TBLA 5IY4A 1UL1A 1UD9A 2NTIA 1B8HA 3HSLX 5CFKA 5E0TA 1CZDA 1B77A 3GPMA 1AXCA 2ZVLA 1PLQA 1VYMA 1YYPA 5E0VA 2NTIC 3G65B 4D2GA 1IZ5A 2IO4B 3G65A 4L6PA 5AUJA 3AIXA 2AVTA 3A1JA 2Z0LA 2IO4A 1T6LA 3G65C 5HACA 1U76A 3A2FB 1GE8A 2ZVMA 1U7BA 3A1JC 3I2MX 2HIIA 3U60F 2AWAA 3P91A 2HIKB 3AIXB 4L60A 3GGRB 1DMLA 3AIZA 3A1JB 3LX1A 2IJXA 3WGWA 2HIKA 5JNED 3GGRA 2IX2B 3AIZC 3GPNA 3U61F 2HIIB 3V60B 1ISQA 2HIKC 3P87A 5IWDA 2IX2A 1RWZA 3VKXA 5E0UA 2ZVWA 3HI8A 3GGRC 5B7OA 4TR6A 2IZOB 1SXJF 2ZVKA 1W60A 2IX2C 5H0TA 3K4XA 3FDSD 3LX2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YHR A;  3IFV A;  1RXZ A;  2HII C;  2OD8 A;  3V62 B;  1PLR A;  5DAI A;  4CS5 A;  4HK1 A;  5DA7 A;  5A6D A;  3V61 B;  5IXA A;  3FDS C;  3F1W A;  4RJF A;  1VYJ A;  1RXM A;  1IZ4 A;  2IZO C;  4ZTD A;  3U5Z F;  2ZVV A;  3P83 A;  2NTI B;  3TBL A;  5IY4 A;  1UL1 A;  1UD9 A;  2NTI A;  1B8H A;  3HSL X;  5CFK A;  5E0T A;  1CZD A;  1B77 A;  3GPM A;  1AXC A;  2ZVL A;  1PLQ A;  1VYM A;  1YYP A;  5E0V A;  2NTI C;  3G65 B;  4D2G A;  1IZ5 A;  2IO4 B;  3G65 A;  4L6P A;  5AUJ A;  3AIX A;  2AVT A;  3A1J A;  2Z0L A;  2IO4 A;  1T6L A;  3G65 C;  5HAC A;  1U76 A;  3A2F B;  1GE8 A;  2ZVM A;  1U7B A;  3A1J C;  3I2M X;  2HII A;  3U60 F;  2AWA A;  3P91 A;  2HIK B;  3AIX B;  4L60 A;  3GGR B;  1DML A;  3AIZ A;  3A1J B;  3LX1 A;  2IJX A;  3WGW A;  2HIK A;  5JNE D;  3GGR A;  2IX2 B;  3AIZ C;  3GPN A;  3U61 F;  2HII B;  3V60 B;  1ISQ A;  2HIK C;  3P87 A;  5IWD A;  2IX2 A;  1RWZ A;  3VKX A;  5E0U A;  2ZVW A;  3HI8 A;  3GGR C;  5B7O A;  4TR6 A;  2IZO B;  1SXJ F;  2ZVK A;  1W60 A;  2IX2 C;  5H0T A;  3K4X A;  3FDS D;  3LX2 A; 
#chains in the Genus database with same CATH topology
 4YHR A;  3IFV A;  1RXZ A;  2HII C;  2OD8 A;  3V62 B;  1PLR A;  5DAI A;  4CS5 A;  4HK1 A;  5DA7 A;  5A6D A;  3V61 B;  5IXA A;  3FDS C;  3F1W A;  4RJF A;  1VYJ A;  1RXM A;  1IZ4 A;  2IZO C;  4ZTD A;  3U5Z F;  2ZVV A;  3P83 A;  2NTI B;  3TBL A;  5IY4 A;  1UL1 A;  1UD9 A;  2NTI A;  1B8H A;  3HSL X;  5CFK A;  5E0T A;  1CZD A;  1B77 A;  3GPM A;  1AXC A;  2ZVL A;  1PLQ A;  1VYM A;  1YYP A;  5E0V A;  2NTI C;  3G65 B;  4D2G A;  1IZ5 A;  2IO4 B;  3G65 A;  4L6P A;  5AUJ A;  3AIX A;  2AVT A;  3A1J A;  2Z0L A;  2IO4 A;  1T6L A;  3G65 C;  5HAC A;  1U76 A;  3A2F B;  1GE8 A;  2ZVM A;  1U7B A;  3A1J C;  3I2M X;  2HII A;  3U60 F;  2AWA A;  3P91 A;  2HIK B;  3AIX B;  4L60 A;  3GGR B;  1DML A;  3AIZ A;  3A1J B;  3LX1 A;  2IJX A;  3WGW A;  2HIK A;  5JNE D;  3GGR A;  2IX2 B;  3AIZ C;  3GPN A;  3U61 F;  2HII B;  3V60 B;  1ISQ A;  2HIK C;  3P87 A;  5IWD A;  2IX2 A;  1RWZ A;  3VKX A;  5E0U A;  2ZVW A;  3HI8 A;  3GGR C;  5B7O A;  4TR6 A;  2IZO B;  1SXJ F;  2ZVK A;  1W60 A;  2IX2 C;  5H0T A;  3K4X A;  3FDS D;  3LX2 A; 
#chains in the Genus database with same CATH homology
 4YHR A;  3IFV A;  1RXZ A;  2HII C;  2OD8 A;  3V62 B;  1PLR A;  5DAI A;  4CS5 A;  4HK1 A;  5DA7 A;  5A6D A;  3V61 B;  5IXA A;  3FDS C;  3F1W A;  4RJF A;  1VYJ A;  1RXM A;  1IZ4 A;  2IZO C;  4ZTD A;  3U5Z F;  2ZVV A;  3P83 A;  2NTI B;  3TBL A;  5IY4 A;  1UL1 A;  1UD9 A;  2NTI A;  1B8H A;  3HSL X;  5CFK A;  5E0T A;  1CZD A;  1B77 A;  3GPM A;  1AXC A;  2ZVL A;  1PLQ A;  1VYM A;  1YYP A;  5E0V A;  2NTI C;  3G65 B;  4D2G A;  1IZ5 A;  2IO4 B;  3G65 A;  4L6P A;  5AUJ A;  3AIX A;  2AVT A;  3A1J A;  2Z0L A;  2IO4 A;  1T6L A;  3G65 C;  5HAC A;  1U76 A;  3A2F B;  1GE8 A;  2ZVM A;  1U7B A;  3A1J C;  3I2M X;  2HII A;  3U60 F;  2AWA A;  3P91 A;  2HIK B;  3AIX B;  4L60 A;  3GGR B;  1DML A;  3AIZ A;  3A1J B;  3LX1 A;  2IJX A;  3WGW A;  2HIK A;  5JNE D;  3GGR A;  2IX2 B;  3AIZ C;  3GPN A;  3U61 F;  2HII B;  3V60 B;  1ISQ A;  2HIK C;  3P87 A;  5IWD A;  2IX2 A;  1RWZ A;  3VKX A;  5E0U A;  2ZVW A;  3HI8 A;  3GGR C;  5B7O A;  4TR6 A;  2IZO B;  1SXJ F;  2ZVK A;  1W60 A;  2IX2 C;  5H0T A;  3K4X A;  3FDS D;  3LX2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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